CN201058029Y - System for gathering and producing autoserum eye water - Google Patents
System for gathering and producing autoserum eye water Download PDFInfo
- Publication number
- CN201058029Y CN201058029Y CNU2007200137423U CN200720013742U CN201058029Y CN 201058029 Y CN201058029 Y CN 201058029Y CN U2007200137423 U CNU2007200137423 U CN U2007200137423U CN 200720013742 U CN200720013742 U CN 200720013742U CN 201058029 Y CN201058029 Y CN 201058029Y
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- eye water
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Abstract
Disclosed is a self-serum eyedrop collecting and preparing system, belonging to the medicine field and solving the problem that the present self-serum eyedrop preparation needs high demand to the environment. The self-serum eyedrop collecting and preparing system comprises a blood collecting unit, a plasma dilution bottle and a separating unit. The whole system is arranged in a sterile sealed package; a blood inlet tube and a serum outlet tube is inserted in a blood collecting bottle through rubber plugs; the inside cavity of the blood collecting bottle is under subpressure; the other end of the serum outlet tube is inserted into the plasma dilution bottle in which BSS solution is arranged, the orifice of the serum outlet tube is closed and the inside cavity of the tube is under vacuum subpressure; the plasma dilution bottle is communicated with a compressed liquid capsule through a connecting thin tube and the compressed liquid capsule is connected with a separating eyedrop bottle through a guide tube. The whole collecting system is positioned in the sterile sealed package, ensuring the process of extracting and preparing the serum eyedrop is operated under the sterile environment and conforming to the preparation need of the self-serum eyedrop; the whole collecting process ensures the collecting work of the self-serum eyedrop to be simple and practical, convenient for development in the primary hospitals.
Description
Technical field:
This utility model belongs to field of medicaments, is a kind of system that is used to prepare autoserum eye water specifically.
Background technology:
Contain fibronectin, abundant vitamin A and cytokine (as TGF, FGF, EGF, IGF, NGF etc.) in the serum, be used for a regeneration and a reparation that eye drip can quicken eye table epithelium; The excretory lipid of the alternative tarsal glands of oiliness composition in the serum, prealbumin can increase the stability of tear film; Also contain a large amount of aminoacid, peptide class, nucleic acid connection material, sugar and Organic substance in the serum, can improve histotrophic nutrition, irritation cell regeneration, acceleration of tissue repair; Comprise many antimicrobial factorses in the serum, as: IgG, lysozyme and complement have the effect of certain inhibition antibacterial; Autoserum does not have anaphylactogen.Therefore, be made into eye drop and in the clinical treatment of eye surface diseases, obtained using widely, and obtained good and clinical curative effect.The clinical ophthalmology indication mainly contains: serious xerophthalmia; The persistence corneal epithelial defect; The Stevens-Johnson syndrome; Eye spot pemphigoid; Cornea anterior basal membrane malnutrition occurs epithelial erosion repeatedly and strips off; Top limbus of corneae keratoconjunctivitis; The auxiliary treatment of cornea stem cell transplantation art, the operation of eye table amniotic membrane etc.
But, should not add antiseptic in the serum eye water, to avoid the toxic action of corneal epithelial; Extract and the process of configuration serum eye water should guarantee strict aseptic manipulation, and need in superclean bench, carry out, pollute avoiding.Therefore, the application of autoserum eye water is restricted always, is difficult to carry out at basic hospital.
Summary of the invention:
In order to solve the problem of above-mentioned existence, this utility model provides a kind of autoserum eye hydromining collection preparation system easy and simple to handle.Goal of the invention of the present utility model is achieved through the following technical solutions: autoserum eye hydromining collection preparation system, comprise blood-taking device, the diluted plasma bottle, packaging device, whole system places aseptic airtight package, blood-taking device comprises blood vial, advance blood vessel, go out serum tube, packaging device comprises can press sunken liquid capsule, conduit and packing eye water bottle, on the blood vial top plug is housed, on plug, be inserted with breather, advance blood vessel and go out serum tube and pass plug and be inserted in the blood vial, in the blood vial is negative pressure, go out the serum tube other end and insert in the diluted plasma bottle, and detachable, in the diluted plasma bottle balanced salt solution is housed, the mouth of pipe seals with plug, is inserted with breather on plug, negative pressure of vacuum in the pipe, the diluted plasma bottle is communicated with pressing sunken liquid capsule by connecting tubule, can press sunken liquid capsule to be connected with some packing eye water bottles by conduit, the about 0.5～3ml of capacity of packing eye water bottle, each two ends, packing eye water bottle middle and lower part is shaped on opening, be communicated with conduit, be provided with stopper at catheter tip.
Packaging device comprises conduit, packing eye water bottle, packing eye water bottle is to fall into the body that expands that material makes by pressing, the diluted plasma bottle is communicated with by being connected tubule with packing eye water bottle, and it is detachable, about 0.3～the 2ml of capacity of packing eye water bottle, connected by tubule between each packing eye water bottle, integral body is arranged and is " U " shape, the about 0.5～3mm of tubule internal diameter; Attached at packing eye water bottle bottle mouth position with bottle stopper, make the sealing of packing eye water bottle after turning, blood vial and diluted plasma bottle are in sustained height, and packaging device is in it down, or turningly moves to it down.
Can open air valve going out to be provided with on the serum tube.
Between diluted plasma bottle and packing eye water bottle be connected to be provided with on the tubule can be opened air valve.
The using method of autoserum eye hydromining collection preparation system: blood taking needle one end is by the blood vessel that advances of plug insertion system, and the other end communicates with patient's vein, gathers a certain amount of blood and enters blood vial; Room temperature left standstill 2 hours or 4 degree left standstill 48 hours, after the limpid serum to be formed, adjust the height of serum tube, make its lower end just on the sludged blood plane, (leave certain distance), disassemble (or the breather on the unlatching plug) from the packing plug entering blood vessel mouth upper end; Open the air valve (or the going out serum tube that will partly insert before in the plug inserts in the bottle) between blood vial and the diluted plasma bottle, blood vial is communicated with the diluted plasma bottle, mix with wherein balanced salt solution (BSS liquid) at the effect hematochezia clear stream of negative pressure of vacuum to dilution bottle, after the serum for the treatment of appropriate amount (BSS liquid total amount 1/4) flow to dilution bottle, close the valve between two pipes, the jog whole system makes serum and the complete mixing of balanced salt solution; Air valve between unlatching and packing eye water bottle, making serum after the dilution be charged to packing eye water bottle by action of gravity (also can be furnished with and can press the system that falls into the liquid capsule, can press sunken liquid capsule to quicken serum eye water and be filled into packing eye water bottle), treat that last expands part valve-off will be full of the time, with packing eye water bottle be connected tubule and separate, close two bottle stoppers across outer package and make whole packing eye water bottle part complete closed.Take outer package apart, seal tubule between each packing eye water bottle, each packing eye water bottle is isolated mutually with heat sealing machine (or thermal jointing clipper).Packing eye water bottle is put into refrigerator to be preserved.
The beneficial effects of the utility model: this utility model adopts said structure, because whole acquisition system is in the aseptic airtight package, guarantees that the process of extracting and prepare serum eye water operates under aseptic environments, meets the preparation needs of autoserum eye water; And the serum eye water of last encapsulation is fractional pack independently, is convenient to preserve and use; Whole gatherer process makes the collecting work of autoserum eye water simple and easy to do in addition, is convenient to carry out at basic hospital.
Description of drawings:
Fig. 1 is the structural representation of autoserum eye hydromining collection preparation system;
Fig. 2 is the structural representation of the another kind of embodiment of autoserum eye hydromining collection preparation system.
The specific embodiment:
Embodiment 1: autoserum eye hydromining collection preparation system, comprise sterile closed packaging bag 4, blood-taking device, diluted plasma bottle 2, packaging device, whole system places aseptic airtight package bag 4, blood-taking device comprises blood vial 1, advance blood vessel 5, go out serum tube 6, packaging device comprises can press sunken liquid capsule 15, connect tubule 11 and packing eye water bottle 9, on blood vial 1 top plug 7 is housed, on plug 7, be inserted with breather 14, advance blood vessel 5 and go out serum tube 6 and pass plug 7 and be inserted in the blood vial 1, in the blood vial is negative pressure, diluted plasma bottle two ends plug 8,17 sealings, on plug 17, be inserted with breather 19, negative pressure of vacuum in the pipe, going out serum tube 6 other ends passes in the plug 17 insertion diluted plasma bottles 2, and it is detachable, an amount of balanced salt solution (BSS liquid) is housed in the diluted plasma bottle 2, BSS liquid is advisable with 4: 1 with the ratio of gathering serum amount, diluted plasma bottle 2 is communicated with by being connected tubule 11 with pressing sunken air bag 15, can press sunken liquid capsule 15 to be connected with packing eye water bottle 9 by conduit 3, about 0.5～the 3ml of capacity of packing eye water bottle, its quantity can be set as required, as shown in Figure 1, packing eye water bottle is 4, each two ends, packing eye water bottle middle and lower part is shaped on opening, be communicated with conduit, be provided with stopper 18 at conduit 3 ends.
Embodiment 2: autoserum eye hydromining collection preparation system, comprise sterile closed packaging bag 4, blood-taking device, diluted plasma bottle 2, packaging device, whole system places aseptic airtight package bag 4, blood-taking device comprises blood vial 1, advance blood vessel 5, go out serum tube 6, blood vial 1 and diluted plasma bottle 2 are in sustained height, packaging device is in it down, or turning moving under it, packaging device comprises connection tubule 11, packing eye water bottle 9, packing eye water bottle 9 is to fall into material and make and expand body by pressing, and the about 0.3～2ml of capacity of packing eye water bottle 9 is connected by tubule 16 between each packing eye water bottle, integral body is arranged and is " U " shape, the about 0.5～3mm of tubule 16 internal diameters; Attached at packing eye water bottle bottle mouth position with bottle stopper 13, make 9 sealings of packing eye water bottle after turning, blood vial 1 is a vacuum, advancing blood vessel 5 is inserted in the blood vial 1, the bottom is near the plug 7 of blood vial, going out serum tube 6 one ends is inserted in the blood vial 1, the other end is inserted in the diluted plasma bottle 2, it is detachable to go out serum tube 6, can open air valve 10 going out to be provided with on the serum tube 6, balanced salt solution (BSS liquid) is housed in the diluted plasma bottle 2, BSS liquid is advisable with 4: 1 with the ratio of gathering serum amount, the mouth of pipe seals with plug 8, negative pressure of vacuum in the pipe, the mouth of pipe down, diluted plasma bottle 2 and packing eye water bottle 9 are by being connected tubule 11 connections, and detachable, on connection tubule 11, be provided with and can open air valve 12.
Claims (4)
1. autoserum eye hydromining collection preparation system, it is characterized in that: comprise blood-taking device, the diluted plasma bottle, packaging device, whole system places aseptic airtight package, blood-taking device comprises blood vial, advance blood vessel, go out serum tube, packaging device comprises can press sunken liquid capsule, conduit and packing eye water bottle, on the blood vial top plug is housed, on plug, be inserted with breather, advance blood vessel and go out serum tube and pass plug and be inserted in the blood vial, in the blood vial is negative pressure, go out the serum tube other end and insert in the diluted plasma bottle, and detachable, in the diluted plasma bottle balanced salt solution is housed, the mouth of pipe seals with plug, is inserted with breather on plug, negative pressure of vacuum in the pipe, the diluted plasma bottle is communicated with pressing sunken liquid capsule by connecting tubule, can press sunken liquid capsule to be connected with some packing eye water bottles by conduit, the about 0.5～3ml of capacity of packing eye water bottle, each two ends, packing eye water bottle middle and lower part is shaped on opening, be communicated with conduit, be provided with stopper at catheter tip.
2. autoserum eye hydromining collection preparation system according to claim 1, it is characterized in that: described packaging device comprises connection tubule, packing eye water bottle, packing eye water bottle is to fall into the body that expands that material makes by pressing, the diluted plasma bottle is communicated with by being connected tubule with packing eye water bottle, and detachable, the about 0.3～2ml of capacity of packing eye water bottle is connected by tubule between each packing eye water bottle, integral body is arranged and is " U " shape, the about 0.5～3mm of tubule internal diameter; Attached at packing eye water bottle bottle mouth position with bottle stopper, make the sealing of packing eye water bottle after turning, blood vial and diluted plasma bottle are in sustained height, and packaging device is in it down, or turningly moves to it down.
3. autoserum eye hydromining collection preparation system according to claim 1 and 2 is characterized in that: can open air valve going out to be provided with on the serum tube.
4. autoserum eye hydromining collection preparation system according to claim 2 is characterized in that: between diluted plasma bottle and packing eye water bottle be connected to be provided with on the tubule can be opened air valve.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2007200137423U CN201058029Y (en) | 2007-08-09 | 2007-08-09 | System for gathering and producing autoserum eye water |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2007200137423U CN201058029Y (en) | 2007-08-09 | 2007-08-09 | System for gathering and producing autoserum eye water |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201058029Y true CN201058029Y (en) | 2008-05-14 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNU2007200137423U Expired - Lifetime CN201058029Y (en) | 2007-08-09 | 2007-08-09 | System for gathering and producing autoserum eye water |
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| CN (1) | CN201058029Y (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010136535A1 (en) * | 2009-05-27 | 2010-12-02 | Justus-Liebig-Universität Giessen | Device and method for producing blood products |
| CN104248511A (en) * | 2014-10-21 | 2014-12-31 | 武汉佰美斯医疗科技有限公司 | Blood bag with rhizoma nelumbinis type sample reserving tube and production method of blood bag |
| CN105293415A (en) * | 2008-11-14 | 2016-02-03 | 威尔泰克联合股份有限公司 | Apparatus and method for mixing and dispensing |
| WO2020086106A1 (en) * | 2018-10-25 | 2020-04-30 | Thorne Intellectual Property Holdings, Llc | Methods for preparing autologous blood eye drops |
| WO2022028219A1 (en) * | 2020-08-01 | 2022-02-10 | 河南方舟医疗器械有限公司 | Sterile preparation, packaging, and output system for blood serum, and method |
| KR20230064206A (en) * | 2021-11-03 | 2023-05-10 | 김용현 | Serum distribution apparatus and serum distribution kit including the same |
-
2007
- 2007-08-09 CN CNU2007200137423U patent/CN201058029Y/en not_active Expired - Lifetime
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105293415A (en) * | 2008-11-14 | 2016-02-03 | 威尔泰克联合股份有限公司 | Apparatus and method for mixing and dispensing |
| US10399846B2 (en) | 2008-11-14 | 2019-09-03 | Veltek Associates, Inc. | Apparatus and method for mixing and dispensing |
| WO2010136535A1 (en) * | 2009-05-27 | 2010-12-02 | Justus-Liebig-Universität Giessen | Device and method for producing blood products |
| CN104248511A (en) * | 2014-10-21 | 2014-12-31 | 武汉佰美斯医疗科技有限公司 | Blood bag with rhizoma nelumbinis type sample reserving tube and production method of blood bag |
| WO2020086106A1 (en) * | 2018-10-25 | 2020-04-30 | Thorne Intellectual Property Holdings, Llc | Methods for preparing autologous blood eye drops |
| WO2022028219A1 (en) * | 2020-08-01 | 2022-02-10 | 河南方舟医疗器械有限公司 | Sterile preparation, packaging, and output system for blood serum, and method |
| JP2023519571A (en) * | 2020-08-01 | 2023-05-11 | 河南方舟医療器械有限公司 | Serum sterile preparation subpackage dispensing system and method |
| JP7388783B2 (en) | 2020-08-01 | 2023-11-29 | 河南方舟医療器械有限公司 | Serum sterile preparation subpackage dispensing system and method |
| KR20230064206A (en) * | 2021-11-03 | 2023-05-10 | 김용현 | Serum distribution apparatus and serum distribution kit including the same |
| KR102601884B1 (en) | 2021-11-03 | 2023-11-14 | 김용현 | Serum distribution apparatus and serum distribution kit including the same |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CX01 | Expiry of patent term | ||
| CX01 | Expiry of patent term |
Granted publication date: 20080514 |