CN201049109Y - Remifentanil intelligent infusion/injection control device - Google Patents
Remifentanil intelligent infusion/injection control device Download PDFInfo
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- CN201049109Y CN201049109Y CNU2007200510724U CN200720051072U CN201049109Y CN 201049109 Y CN201049109 Y CN 201049109Y CN U2007200510724 U CNU2007200510724 U CN U2007200510724U CN 200720051072 U CN200720051072 U CN 200720051072U CN 201049109 Y CN201049109 Y CN 201049109Y
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Abstract
An infusion control device used in remifentanil feedback control administration comprises an electric source (3), an infusion actuator (1) and a control device (2), wherein, the control device consists of an electric source management module, a control module of the infusion actuator, a central control singlechip with a built-in control program, an electrocardiogram (ECG) monitoring module with ECG electrodes, a display device and an input device; the electric source realizes power supply for each device through the electric source management module; the singlechip is in electrical connection with the electric source management module, the control module of the infusion actuator, the display device and the input device through data lines; the output signal of the electrocardiogram monitoring module is transmitted to the signal input end of the singlechip through a network interface. The patent realizes obvious reduction in arrhythmia and increases medication safety; the control device is convenient for use and can complete automatic administration and other operations after the basic heart rate of a patient and a heart rate control range are input, thereby realizing programmed and sequential administration for intravenous anesthesia.
Description
Technical field
It is the infusion control device of index feedback control intravenous anesthesia medicine remifentanil with the changes in heart rate that this utility model relates to a kind of.
Background technology
Because intravenous anesthesia is applicable to the patient that all can vein open, is more and more accepted by vast anesthesia doctor.But there is certain shortcoming in intravenous anesthesia medication commonly used at present, and can make as the gradation intravenously administrable needs concentration to produce bigger fluctuation, and the constant speed intravenous drip needed for four and half above half-life anti-near stable state, and blood drug level is difficult to control.
Along with development of computer, according to the principle administration of pharmacokinetics, controlled by single chip microprocessor infusion pump, i.e. target controlled infusion (Target Controlled Infusion, TCI) can be based on pharmacokinetics and pharmacodynamics, by regulating drug target concentration control depth of anesthesia.
Existing intravenous anesthesia infusion control device comprises power supply, infusion actuator and control device, and the infusion actuator is made of the motor, driving member and the infusion device that connect successively; Control device is made of central control single chip computer, liquid crystal indicator and the input equipment of power management module, infusion actuating mechanism controls module, built-in control sequence, to each device power supply, single-chip microcomputer has data wire to be electrically connected with power management module, liquid crystal indicator and input equipment respectively to power supply by power management module.The plug-in of central authorities' control single chip computer is controlled blood drug level according to the universal law of summing up, studying, extract by patient parameter setting and target from a large amount of practices.Further research and development direction can be sought and be established the pharmacodynamic index of reliable intravenous anesthetic sensitivity and develop corresponding feedback device to the reaction of certain anesthetics when anaesthetizing infusion according to each patient exactly, and this becomes inevitable trend.
Intelligent infusion control system is meant by the self-regulating drug-supplying system of certain feedback signal, it presses compatriots' intravenous anesthetic for the calmness of mathematic(al) parameter infusion, analgesia and muscle relaxant with the Single-chip Controlling injection device, and be that feedback parameter realizes that closed loop controls administration automatically, regulates patient's depth of anesthesia with the pharmacodynamic index of sensitivity, safe and reliable, anesthesia steady and easy to operate, it has solved the wayward and many shortcomings of anthropic factor influence of previously intravenous anesthesia, realizes intravenous anesthesia sequencing, the administration of sequential property.The feedback index that adopts has BIS value (brain electricity bispectral index at present, prevent to know in the art), HRVI (heart rate variability, prevent excessive stress) and blood pressure and heart rate etc., but still do not have definite and ideal index, be impossible with all medicines of single control indexes.Therefore, seek the relevant pharmacodynamic index of different pharmaceutical and be used to feed back imperative.
Pharmacodynamic index should be able to quantitative parameter be described preferably, drug level is changed responsive relatively, and good repeatability, reliable and clinical meaning arranged is arranged.Remifentanil is the μ receptor stimulating agent, and analgesic effect is good, action time is short and controllability is good, is ideal intravenous anesthesia target controlled infusion medicine; But clinical research finds that remifentanil has side effect such as respiration inhibition, muscle rigidity, hypopiesia, bradycardia, and injection speed and blood drug level control have a significant effect to its anesthesia usefulness and side effect.The remifentanil pharmacodynamic index can be used marginal frequency, respiration inhibition or clinical sign etc.The index of correlation is 0.930 when having confirmed that HR is the remifentanil pharmacodynamics index, can quantize the drug effect of remifentanil well as pharmacodynamic index.
The utility model content
The purpose of this utility model, just provide a kind of possess intelligence, serve as feedback control indexes remifentanil injection speed with real-time heart rate, and then the intelligent infusion control device of remifentanil of control remifentanil blood drug level.
The purpose of this utility model is to realize by following technical scheme: the intelligent infusion control device of a kind of remifentanil, comprise power supply, infusion actuator and control device, control device is made of central control single chip computer, display device and the input equipment of power management module, the control module of infusion actuator, built-in control sequence, power supply is subjected to power management module control to each device power supply, and central control single chip computer has data wire to be electrically connected with control module, display device and the input equipment of power management module, infusion actuator respectively; It is characterized in that: described control device also comprises the cardiac monitoring module of being with electrocardioelectrode, and its output signal is connected to the signal input part of central control single chip computer by network interface.
Described infusion actuator is the controlled syringe pump that remifentanil is housed; Or by controllable motor, turn-screw guide rail, be placed in the syringe that remifentanil is housed on the fixed mount and constitute, the output of controllable motor drives the turn-screw pushing syringe.
Described display device is a LCDs.
Described input equipment is keyboard or touch screen.
On the basis of the above, this utility model can be done following improvement:
Described infusion actuator also comprises infusion ultimate position pick off.
Described power supply also comprises backup battery, and it is connected with power management module by data wire.
The beneficial effects of the utility model are:
1. the basic research of this patent has confirmed that heart rate is the effective pharmacodynamic index of remifentanil, and remifentanil blood drug level and changes in heart rate have good dependency, but by changes in heart rate feedback control remifentanil blood drug level, and then the control depth of anesthesia.
2. heart rate is a physiological parameters of patients, is monitoring index the most frequently used in the clinical operation process, does not influence the enforcement of operation and anesthesia, easily obtains, and does not increase patient trauma and financial burden.
3. remifentanil is potent μ receptor agonism medicine, and to the heart rate influence obviously, heart rate obviously slowed down even danger when injection speed was excessive.The unlikely obvious reduction of this patent control heart rate has increased the safety of medication.
4. the intelligent infusion control device of remifentanil is easy to use, LCDs shows multinomial data such as needing concentration in injection process, have good real time performance, as long as input patient's basal heart rate and heart rate span of control, this device gets final product automatic chemical feeding, and all are finished automatically by device.As adjusting concentration range, reconfigurable new heart rate span of control gets final product.
Description of drawings
Accompanying drawing is a principle assumption diagram of the present utility model.
The specific embodiment
As shown in drawings, the intelligent infusion control device of this novel remifentanil embodiment, comprise infusion actuator 1, control device 2 and power supply 3, the infusion actuator by controllable motor, turn-screw guide rail, be placed in syringe and position sensor that remifentanil is housed on the fixed mount and constitute, the output of controllable motor drives the turn-screw pushing syringe; Control device is made of central control single chip computer, LCDs and the finger-impu system of power management module, the control module of infusion actuator, built-in control sequence, AC-DC Switching Power Supply and the backup battery of power supply for having control line to be connected with power management module respectively, power supply are powered to each device by power management module control; Single-chip microcomputer has data wire to be electrically connected with control module, position sensor, LCDs and the keyboard of power management module, infusion actuator respectively, the output control controllable motor of control module, control device also includes electrocardiogram monitor, it includes the electrocardioelectrode that can be placed in patient's chest, and the outfan of electrocardiogram monitor is connected to the input of single-chip microcomputer by the networking interface.
The electrocardioelectrode of electrocardiogram monitor is placed in patient's chest collection, the monitoring patient rhythm of the heart, and patient's real-time heart rate is sent in the single-chip microcomputer as the feedback index by the networking interface, single-chip microcomputer calculates relatively patient's heart rate value and conduct feedback index heart rate value at this moment according to plug-in, and transmit control signal and be sent to the control module of infusion actuator, then, the control module drive motors of infusion actuator drive turn-screw pushing syringe carries out infusion to the patient.Along with the increase of remifentanil injection speed and blood drug level, patient heart rate slows down, the reduction of remifentanil injection speed and blood drug level, and heart rate increases.
This device is by being benchmark with the patient base heart rate, the remifentanil administration is controlled on the pharmacodynamic index feedback ground that is changed to heart rate, be equipped with tranquilizer and muscle relaxant and anesthetic machine control breathing again, can guarantee safety in patient's art, provide condition smoothly for performing the operation.
Infusion ultimate position pick off sends the single-chip microcomputer output alarm that signal is given control device after infused.
Characteristics of the present utility model are: can control the Remifentanil blood concentration by changes in heart rate, and then control anesthesia The degree of depth; Heart rate is physiological parameters of patients, is monitoring index the most frequently used in the clinical operation process, does not affect operation and fiber crops Liquor-saturated enforcement does not increase patient trauma and financial burden; Remifentanil is obvious to the heart rate impact, when injection speed is excessive Heart rate obviously slows down even is dangerous. The unlikely obvious reduction of this patent control heart rate has increased the security of medication; And make With convenient, as long as input patient's basal heart rate and Rate control scope, this device gets final product automatic chemical feeding, and all are by device Automatically finish, realized Intravenous Anesthesia sequencing, sequential administration.
Claims (4)
1. the intelligent infusion control device of a remifentanil, comprise power supply (3), infusion actuator (1) and control device (2), control device is made of central control single chip computer, display device and the input equipment of power management module, the control module of infusion actuator, built-in control sequence, power supply is subjected to power management module control to each device power supply, and central control single chip computer has data wire to be electrically connected with control module, display device and the input equipment of power management module, infusion actuator respectively; It is characterized in that: described control device also comprises the cardiac monitoring module of being with electrocardioelectrode, and its output signal is connected to the signal input part of central control single chip computer by network interface.
2. the intelligent infusion control device of remifentanil according to claim 1 is characterized in that: described infusion actuator (1) is for being equipped with the controlled syringe pump of remifentanil; Or by controllable motor, turn-screw guide rail, be placed in the syringe that remifentanil is housed on the fixed mount and constitute, the output of controllable motor drives the turn-screw pushing syringe.
3. the intelligent infusion control device of remifentanil according to claim 1 and 2, it is characterized in that: described infusion actuator (1) also comprises infusion ultimate position pick off, it exports the central control single chip computer of control device to.
4. the intelligent infusion control device of remifentanil according to claim 3, it is characterized in that: described display device is a LCDs, and described input equipment is keyboard or touch screen, and described power supply also comprises backup battery.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2007200510724U CN201049109Y (en) | 2007-04-30 | 2007-04-30 | Remifentanil intelligent infusion/injection control device |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNU2007200510724U CN201049109Y (en) | 2007-04-30 | 2007-04-30 | Remifentanil intelligent infusion/injection control device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN201049109Y true CN201049109Y (en) | 2008-04-23 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNU2007200510724U Expired - Fee Related CN201049109Y (en) | 2007-04-30 | 2007-04-30 | Remifentanil intelligent infusion/injection control device |
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| Country | Link |
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| CN (1) | CN201049109Y (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4138952A1 (en) * | 2020-04-20 | 2023-03-01 | Fresenius Kabi USA, LLC | Fluid pump notification and control based on monitored feedback |
-
2007
- 2007-04-30 CN CNU2007200510724U patent/CN201049109Y/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4138952A1 (en) * | 2020-04-20 | 2023-03-01 | Fresenius Kabi USA, LLC | Fluid pump notification and control based on monitored feedback |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20080423 Termination date: 20110430 |