CN200977192Y

CN200977192Y - Micro dialysis probe percutaneous implantation positioning puncture guiding needle

Info

Publication number: CN200977192Y
Application number: CN 200620045344
Authority: CN
Inventors: 肖湘生; 安潇; 刘士远; 陶晓峰; 董生; 董伟华; 贾宁阳
Original assignee: Second Military Medical University SMMU
Current assignee: Second Military Medical University SMMU
Priority date: 2006-08-31
Filing date: 2006-08-31
Publication date: 2007-11-21
Anticipated expiration: 2016-08-31

Abstract

The utility model relates to the medical apparatus technical field, and is a stereotactic aspiration guide pin for embedding a microdialysis probe into the target tissue inside the organism through the skin. The utility model comprises a needle sheath (1), a needle tube (2) and a needle core (3); the needle sheath is a flat head soft plastics casing pipe, covered outside the needle tube, and the needle core is inserted into the needle tube. During operation, the needle insertion will be performed accord with the beforehand locating and designed circuit under the monitoring of a photographic equipment; the needle is passing through the target tissue, then go out of the body surface; making the needle sheath exposed for 2cm and fixing the end, then back the needle tube and the need core out of the needle sheath, and then insert the microdialysis probe into the needle sheath; making the semi permeable membrane are of the probe arranged into the target tissue according to the scale on the needle sheath; after the probe has been fixed then back out of the needle sheath, the microdialysis apparatus can be connected normally and begin the sampling. The utility model has a simple structure, and compared with the existing method which the probe is embedded by operation, the utility is safe and convenient; the damage to the organism is also little, the sampling will accord with the actual physiological condition, and is convenient for analytic study or diagnosis therapy.

Description

The microdialysis probe percutaneous is implanted the stereotactic puncture guide pin

Technical field

This utility model relates to technical field of medical instruments, is a kind of stereotactic puncture guide pin that is used for microdialysis probe percutaneous implanting to human body inner target tissue.

Background technology

Microdialysis (microdialysis) is from a kind of micro-biochemistry detection technique at body that last century, the eighties grew up, and is commonly used in the pharmacokinetics experiment.Micro-dialysis device is so that small-molecule substance can macromolecular substances can not be a kind of biological living sampling device of principle design through semipermeable membrane through semipermeable membrane spreads along Concentraton gradient.The line style microdialysis probe of microdialysis sampling usefulness is made of the capillary type dialyzer of a 4-10 millimeters long and quartz or the plastic capillary that links to each other with its two ends usually.During detection, the semipermeable membrane zone of probe is imbedded in the tissue to be measured, the two ends of probe are stretched out external, and an end links to each other with micro-injection pump perfusate is continued the input probe, and the other end is then exported dialysis solution and is used for detecting.Because test substance can diffuse into perfusate and reach dynamic equilibrium along concentration difference through semipermeable membrane in organizing, so, get final product the level and the variation thereof of target substance in research organization's extracellular fluid by measuring the concentration of determinand in the output liquid.Use the microdialysis technology will reach the purpose of accurate sampling, probe must accurately place target region, at present methods that adopt surgical operation under direct-view, probe to be imbedded at the target area more, this is that the service manual of commercially available each company's probe is introduced, and also is the method that bibliographical information adopted of numerous use microdialysis technology.It is big that but wound is implanted in operation, and complication such as pneumothorax, hemothorax appear in complicated operation easily when especially probe is imbedded lungs, the lighter influences the accuracy of testing result, weight person jeopardizes life, causes the zoopery success rate not high, and monitoring exists the problem aspect all ethics especially on human body.So can invent a kind of safe and effective and microdialysis line style probe deep internal organs implanted prosthetics that the high complication of success rate is little, it be significant just to seem.

Summary of the invention

This utility model provides a kind of microdialysis probe percutaneous implantation stereotactic puncture pin easy and simple to handle, little to body injury.It is made up of stylophore, needle tubing and nook closing member.Stylophore is to be placed in the outer tack flexible plastic sleeve of needle tubing, the external diameter of its internal diameter and length and needle tubing needle body and length coupling, and tube wall is provided with scale.Needle tubing is made up of needle stand, needle body and needle point, and needle body is a thin metallic tubd, and its front end is a needle point, and tail end and needle stand join, the external diameter coupling of internal diameter and microdialysis probe, and tube wall is provided with scale, and this scale is corresponding with the scale on the stylophore; Needle stand holds the usefulness that punctures for user, hollow, and end is provided with a groove, the effect of prompting scale and pinpoint inclined plane direction during the existing implantable probe of this groove, fixing nook closing member again.Nook closing member is done by needle core base, pin and syringe needle is formed, the profile of needle core base and size are complementary with the interior spatial structure of needle tubing needle stand, it has a projection can be embedded in the groove of needle stand, pin is dried to be a fine wire, the internal diameter of its external diameter and length and needle tubing needle body and length coupling, the inclined-plane of syringe needle and needle tubing pinpoint inclined plane coupling increase the intensity of needle tubing and prevent that when injected organism tissue from entering needle tubing when the effect of nook closing member is implantable probe.

During use, stylophore is enclosed within outside the needle tubing, scale aligns one by one with the corresponding scale of needle tubing, needle point is exposed to outside the stylophore, nook closing member is inserted needle tubing, make the groove of the projection embedding needle stand of needle core base, this moment, the inclined-plane of needle tubing needle point and nook closing member syringe needle just in time overlapped, according to the circuit inserting needle of prior location and design, under monitoring, image documentation equipment passes the target tissue district, pass body surface again, make stylophore expose 2 centimetres and should hold fix after, needle tubing is withdrawed from stylophore together with nook closing member, and the scale of record stylophore both sides inserts stylophore with microdialysis probe then, make the semipermeable membrane of probe be positioned at the target tissue district according to scale, stationary probe withdraws from stylophore gently, can connect the microdialysis instrument routinely and take a sample.

This utility model is simple in structure, and is safe and convenient to use, and body injury is little, and institute's sample thief more meets the actual physiological situation of body, helps analysis and research or diagnoses and treatment.

Description of drawings

Fig. 1 is an overall structure sketch map of the present utility model

Fig. 2 is a stylophore structural representation of the present utility model

Fig. 3 is a needle tubing structural representation of the present utility model

Fig. 4 is a nook closing member structural representation of the present utility model

Fig. 5 is a needle stand structural representation of the present utility model

Fig. 6 is a needle core base structural representation of the present utility model

The specific embodiment

Now in conjunction with the accompanying drawings and embodiments this utility model is described in detail.

This utility model is made up of stylophore 1, needle tubing 2 and nook closing member 3.Stylophore 1 is for being placed in the tack flexible plastic sleeve outside the needle tubing, and the external diameter of its internal diameter and length and needle tubing needle body and length are mated, and tube wall is provided with scale 1.1.Needle tubing 2 is made up of needle stand 2.1, needle body 2.2 and needle point 2.3, and needle body 2.2 is a thin metallic tubd, and its front end is a needle point 2.3, tail end and needle stand 2.1 join, the external diameter coupling of internal diameter and microdialysis probe, tube wall is provided with scale, and this scale is corresponding with the scale 1.1 on the stylophore; Needle stand 2.1 holds the usefulness that punctures for user, hollow, and end is provided with a groove 2.1.1, the effect of prompting scale and pinpoint inclined plane direction during the existing implantable probe of this groove, fixing nook closing member again.Nook closing member 3 is made up of needle core base 3.1, pin dried 3.2 and syringe needle 3.3, the profile of needle core base 3.1 and size are complementary with the interior spatial structure of needle tubing needle stand 2.1, it has a protruding 3.1.1 can be embedded in the groove 2.1.1 of needle stand, it is a fine wire that pin does 3.2, the internal diameter of its diameter and length and needle tubing needle body 2.2 and length coupling, the inclined-plane coupling of the inclined-plane of syringe needle 3.3 and needle tubing needle point 2.3.

0.6 millimeter of embodiment 1 stylophore 1 external diameter, has scale 1.1 by long 15 centimetres; Needle tubing 2 external diameter 25G, long 19.5 centimetres, wherein needle body 2.2 length are 15 centimetres, and its scale and stylophore scale 1.1 match, and needle tubing needle point 2.3 groove angles are 30 degree; 0.018 inch of nook closing member 3 diameter, long 20 centimetres, syringe needle 3.3 is same inclined-plane with needle tubing needle point 2.3, and groove angle is 30 degree.

This utility model can be made different size according to the difference of probe model and puncture internal organs.

Claims

1, a kind of microdialysis probe percutaneous is implanted the stereotactic puncture guide pin, it is characterized in that being made up of stylophore (1), needle tubing (2) and nook closing member (3); Stylophore (1) is for being placed in the tack flexible plastic sleeve outside the needle tubing, and the external diameter of its internal diameter and length and needle tubing needle body and length are mated, and tube wall is provided with scale (1.1); Needle tubing (2) is made up of needle stand (2.1), needle body (2.2) and needle point (2.3), needle body (2.2) is a thin metallic tubd, its front end is needle point (2.3), tail end and needle stand (2.1) join, the external diameter of internal diameter and microdialysis probe coupling, tube wall is provided with scale, and this scale is corresponding with scale (1.1) on the stylophore, needle stand (2.1) hollow, end is provided with a groove (2.1.1); Nook closing member (3) does (3.2) by needle core base (3.1), pin and syringe needle (3.3) is formed, the profile of needle core base (3.1) and size are complementary with the interior spatial structure of needle tubing needle stand (2.1), it has a projection (3.1.1) can be embedded in the groove (2.1.1) of needle stand, it is a fine wire that pin is done (3.2), the internal diameter of its diameter and length and needle tubing needle body (2.2) and length coupling, the inclined-plane coupling of the inclined-plane of syringe needle (3.3) and needle tubing needle point (2.3).