CN1973872A - Medicine for nourishing Yin, invigorating kidney, strengthening physique and nourishing brain and its prepn - Google Patents
Medicine for nourishing Yin, invigorating kidney, strengthening physique and nourishing brain and its prepn Download PDFInfo
- Publication number
- CN1973872A CN1973872A CNA2006101298102A CN200610129810A CN1973872A CN 1973872 A CN1973872 A CN 1973872A CN A2006101298102 A CNA2006101298102 A CN A2006101298102A CN 200610129810 A CN200610129810 A CN 200610129810A CN 1973872 A CN1973872 A CN 1973872A
- Authority
- CN
- China
- Prior art keywords
- parts
- processed
- radix
- fructus
- medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Medicines Containing Plant Substances (AREA)
Abstract
The present invention discloses one kind of medicine for nourishing Yin, invigorating kidney, strengthening physique and nourishing brain and its preparation process. The medicine is prepared with ten kinds of Chinese medicinal materials, including dog kidney, deer's sinew, sparrow meat, donkey kidney, pilose antler, etc. It is developed based on Chinese medicine theory about the functions of kidney. It has high curative effect on various diseases caused by kidney hypofunction, such as climacteric syndrome, prostatic hypertrophy, sexual hypofunction, etc.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition and preparation method, particularly relate to and a kind ofly have enriching yin and nourishing kidney and keep fit the pharmaceutical composition and the preparation method of brain-strengthening.
Background technology
" Hippocampus the kidney invigorating ball " is the ancient doctor's of China prescription, according to the history in surplus the present existing 200 year, in this prescription, only discloses the composition of various medicines and do not have ratio between each composition.We are according to medical practice, and the content of each composition of this prescription is screened, and develop a kind of enriching yin and nourishing kidney and keep fit the medicine of brain-strengthening.
Summary of the invention
The medicine that purpose of the present invention provides a kind of enriching yin and nourishing kidney to keep fit brain-strengthening.
Second purpose of the present invention provides a kind of enriching yin and nourishing kidney and keeps fit the preparation method of medicine of brain-strengthening.
Technical scheme of the present invention is summarized as follows:
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, comprises following component by weight:
Testis et Pentis Canis 1500-2500 part, Ligamentum cervi 20-80 part is taken the lead mouth to go pawl sparrow meat 5500-9500 part, Testis Et penis Equi 750-1100 part, dried shrimps 300-900 part, Cornu Cervi Pantotrichum 500-1200 part, Hippocampus 100-1500 part, HAIQU 200-1000 part, system Os pardi 10-100 part, Gecko 100-850 part, preferably described Testis et Pentis Canis is 1875 parts, described Ligamentum cervi is 40 parts, describedly take the lead mouth to remove the pawl sparrow meat be 7500 parts, described Testis Et penis Equi is 930 parts, and described dried shrimps is 500 parts, and described Cornu Cervi Pantotrichum is 750 parts, described Hippocampus is 375 parts, described HAIQU is 375 parts, and described system Os pardi is 40 parts, and described Gecko is 240 parts.
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, can also comprise by weight: Radix Ginseng 300-1200 part, Radix Astragali 100-1200 part, Radix Angelicae Sinensis 300-1500 part, Radix Rehmanniae Preparata 3000-6000 part, Radix Aconiti Lateralis Preparata 3500-7000 part, Cortex Cinnamomi 200-750 part, Fructus Caryophylli 1500-4500 part, processed with salt Fructus Foeniculi 950-1800 part, Radix Achyranthis Bidentatae 300-1200 part, processed with salt Fructus Psoraleae 700-1700 part, preferably described Radix Ginseng is 750 parts, the described Radix Astragali is 625 parts, and described when being classified as 1000 parts, described Radix Rehmanniae Preparata is 5000 parts, described Radix Aconiti Lateralis Preparata is 5000 parts, described Cortex Cinnamomi is 375 parts, and described Fructus Caryophylli is 2500 parts, and described processed with salt Fructus Foeniculi is 1250 parts, described Radix Achyranthis Bidentatae is 750 parts, and described processed with salt Fructus Psoraleae is 1250 parts.
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, can also comprise by weight: Radix Codonopsis 1200-3000 part, Poria 500-1500 part, Rhizoma Dioscoreae 950-2500 part, charred Cortex Eucommiae 300-1200 part, Rhizoma Cibotii 100-1500 part, processed with wine Herba Cistanches 3000-6500 part, Semen Juglandis 900-1700 part, Herba Epimedii (processed) 900-3500 part, salt is fried Semen Astragali Complanati 900-1700 part.Preferably described Radix Codonopsis is 1875 parts, and described Poria is 750 parts, and described Rhizoma Dioscoreae is 1500 parts, described charred Cortex Eucommiae is 750 parts, and described Rhizoma Cibotii is 375 parts, and described processed with wine Herba Cistanches is 5000 parts, described Semen Juglandis is 1250 parts, and described Herba Epimedii (processed) is 2000 parts, and it is 1250 parts that described salt is fried Semen Astragali Complanati.
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, can also comprise by weight: Fructus Rubi 1000-3000 part, Fructus Lycii 500-1500 part, processed with wine Fructus Schisandrae Chinensis 300-1200 part, Semen Cuscutae 600-1700 part, processed with wine Fructus Corni 500-1800 part, Os Draconis (calcined) 250-1500 part, Radix Glycyrrhizae 100-900 part, preferably described Fructus Rubi is 2000 parts, described Fructus Lycii is 750 parts, described processed with wine Fructus Schisandrae Chinensis is 750 parts, and described Semen Cuscutae is 1250 parts, and described processed with wine Fructus Corni is 750 parts, described Os Draconis (calcined) is 625 parts, and described Radix Glycyrrhizae is 375 parts.
The preparation method of medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, comprises the steps:
(1) takes by weighing Testis et Pentis Canis 1500-2500 part, Ligamentum cervi 20-80 part, take the lead mouth and go pawl sparrow meat 5500-9500 part, Testis Et penis Equi 750-1100 part, dried shrimps 300-900 part, Cornu Cervi Pantotrichum 500-1200 part, Hippocampus 100-1500 part, HAIQU 200-1000 part, system Os pardi 10-100 part, Gecko 100-850 part, Radix Ginseng 300-1200 part, Radix Astragali 100-1200 part, Radix Angelicae Sinensis 300-1500 part, Radix Rehmanniae Preparata 3000-6000 part, Radix Aconiti Lateralis Preparata 3500-7000 part, Cortex Cinnamomi 200-750 part, Fructus Caryophylli 1500-4500 part, processed with salt Fructus Foeniculi 950-1800 part, Radix Achyranthis Bidentatae 300-1200 part, processed with salt Fructus Psoraleae 700-1700 part, Radix Codonopsis 1200-3000 part, Poria 500-1500 part, Rhizoma Dioscoreae 950-2500 part, charred Cortex Eucommiae 300-1200 part, Rhizoma Cibotii 100-1500 part, processed with wine Herba Cistanches 3000-6500 part, Semen Juglandis 900-1700 part, Herba Epimedii (processed) 900-3500 part, salt is fried Semen Astragali Complanati 900-1700 part, Fructus Rubi 1000-3000 part, Fructus Lycii 500-1500 part, processed with wine Fructus Schisandrae Chinensis 300-1200 part, Semen Cuscutae 600-1700 part, processed with wine Fructus Corni 500-1800 part, Os Draconis (calcined) 250-1500 part, Radix Glycyrrhizae 100-900 part;
(2) described charred Cortex Eucommiae is ground into powder, it is standby to cross 120 mesh sieves;
(3) with described Radix Rehmanniae Preparata, take the lead to boil 2-3 time before mouth goes the pawl sparrow meat to add the water of 5-10 times of weight, boiled 2-5 hour at every turn, merge decocting liquid, filter the condensed cream that it is 1.1-1.5 that filtrate is condensed into 45-55 ℃ of relative density;
(4) described Testis Et penis Equi, Testis et Pentis Canis, Ligamentum cervi, dried shrimps are added 3000-5000 times of weight yellow wine and put in the container, sealing, steam exhausted by medical material to yellow wine till, take out drying, crushing screening;
(5) with all the other described 29 flavor decoction pieces crushing screenings; Add the powder that described step (4) makes, add the condensed cream that described step (3) makes, add proper honey and water, pill is rushed circle, and drying is with described Cortex Eucommiae powdered carbon coating, polishing, drying, promptly.
A kind of enriching yin and nourishing kidney of the present invention are kept fit the medicine of brain-strengthening and are had following characteristics:
1. prescription of the present invention meets the argumentation of Chinese medicine to the kidney function.The traditional Chinese medical science is thought kidney controlling essence storage.Kidney governing bones, bone is given birth to marrow, the brain being the reservoir of the marrow, the kidney being the origin of congenital constitution waits argumentation.Generally speaking, the traditional Chinese medical science thinks that kidney plays crucial effects to people's such as aging of human body growth promoter and intelligence advance and retreat life overall process.The present invention instructs to select for use authentic medicinal herbs through the selected concentrated pill of being processed into.Concentrated pill has that dosage is little, effect is high, the mild and persistent characteristics of the property of medicine.
2. to select Hippocampus for use be principal agent in the present invention, and Hippocampus has the effect of the kidney invigorating regulating qi and activating blood, and Compendium of Material Medica thinks that Hippocampus has the merit in " warm water channel, tonifying YANG road "." book on Chinese herbal medicine meets former " says Hippocampus " yang deficiency is used more ", and " South Sea is situated between and speaks " thinks that the Hippocampus master loses night.The present invention also concentrates to have selected for use to have and fills blood, kidney-Yang invigorating, beneficial marrow, bone and muscle strengthening, controls the rare medicinal herbs of dyspnea due to deficiency and have the Gecko of invigorating the lung and the kidney Dingchuan antitussive.Compendium of Material Medica is thought Gecko " tonifying the lung gas, benefiting essence-blood, the supporing yang road of Dingchuan antitussive "." book on Chinese herbal medicine is new again " thinks that Gecko " warming middle-JIAO kidney tonifying, controlling nocturnal emission with astringent drugs is supporing yang " is the treatment sexual impotence and suffers from a deficiency of the kidney and make to breathe heavily indispensable treasure.Assistant is with Semen Juglandis: the strong waist knee joint of tonifying the kidney to consolidate the essence; Fructus Psoraleae: supporing yang the kidney invigorating; Fructus Caryophylli: warming the kidney is supporing yang; Fructus Corni, Fructus Lycii, dried shrimps: invigorating the liver and kidney, benefiting essence-blood; Radix Ginseng, the Radix Astragali: QI invigorating; Radix Angelicae Sinensis, Radix Rehmanniae Preparata: nourish blood, make QI and blood plentifully to consolidate; Poria, Os Draconis: tranquillizing the mind by relieving convulsion nourishes heart.Above medical material selects YAOJING good, and compatibility is proper, for the caused various hypofunction of suffering from a deficiency of the kidney better curative effect is arranged all.
We keep fit the drug nomenclature of brain-strengthening for " Hippocampus the kidney invigorating ball " with a kind of enriching yin and nourishing kidney of the present invention.
The specific embodiment
The present invention is further illustrated below in conjunction with specific embodiment.
Embodiment 1
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, comprises following component by weight: 1875 parts of Testis et Pentis Canis, and 40 parts of Ligamentum cervis take the lead mouth to remove 7500 parts of pawl sparrow meats, 930 parts of Testis Et penis Equi, 500 parts of dried shrimps, 750 parts in Cornu Cervi Pantotrichum, 75 parts of hippocampus 3s, 375 parts of HAIQU, 40 parts of system Os pardis, 240 parts of Geckos.
Embodiment 2
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, comprises following component by weight: 1500 parts of Testis et Pentis Canis, and 50 parts of Ligamentum cervis take the lead mouth to remove 9500 parts of pawl sparrow meats, 750 parts of Testis Et penis Equi, 300 parts of dried shrimps, 800 parts in Cornu Cervi Pantotrichum, 800 parts of Hippocampus, 500 parts of HAIQU, 50 parts of system Os pardis, 300 parts of Geckos.
Embodiment 3
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, comprises following component by weight:
2500 parts of Testis et Pentis Canis, 20 parts of Ligamentum cervis take the lead mouth to remove 6000 parts of pawl sparrow meats, 1000 parts of Testis Et penis Equi, 900 parts of dried shrimps, 500 parts in Cornu Cervi Pantotrichum, 1500 parts of Hippocampus, 1000 parts of HAIQU, 100 parts of system Os pardis, 100 parts of Geckos.
Embodiment 4
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, comprises following component by weight:
1000 parts of Testis et Pentis Canis, 80 parts of Ligamentum cervis take the lead mouth to remove 5500 parts of pawl sparrow meats, 1100 parts of Testis Et penis Equi, 700 parts of dried shrimps, 1200 parts in Cornu Cervi Pantotrichum, 100 parts of Hippocampus, 200 parts of HAIQU, 10 parts of system Os pardis, 850 parts of Geckos.
Embodiment 5
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, add the following component that comprises by weight with each component shown in the embodiment 1: 750 parts of Radix Ginsengs, 625 parts of the Radixs Astragali, 1000 parts of Radix Angelicae Sinensis, 5000 parts of Radix Rehmanniae Preparata, 5000 parts of Radix Aconiti Lateralis Preparata, 375 parts of Cortex Cinnamomis, 2500 parts of Fructus Caryophyllis, 1250 parts in processed with salt Fructus Foeniculi, 750 parts of Radix Achyranthis Bidentataes, 1250 parts of processed with salt Fructus Psoraleaes.
Embodiment 6
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, add the following component that comprises by weight with each component shown in the embodiment 2: 300 parts of Radix Ginsengs, 600 parts of the Radixs Astragali, 300 parts of Radix Angelicae Sinensis, 4000 parts of Radix Rehmanniae Preparata, 7000 parts of Radix Aconiti Lateralis Preparata, 200 parts of Cortex Cinnamomis, 4500 parts of Fructus Caryophyllis, 1800 parts in processed with salt Fructus Foeniculi, 6000 parts of Radix Achyranthis Bidentataes, 700 parts of processed with salt Fructus Psoraleaes.
Embodiment 7
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, add the following component that comprises by weight with each component shown in the embodiment 3: 1200 parts of Radix Ginsengs, 1200 parts of the Radixs Astragali, 700 parts of Radix Angelicae Sinensis, 6000 parts of Radix Rehmanniae Preparata, 3500 parts of Radix Aconiti Lateralis Preparata, 450 parts of Cortex Cinnamomis, 1500 parts of Fructus Caryophyllis, 1000 parts in processed with salt Fructus Foeniculi, 300 parts of Radix Achyranthis Bidentataes, 1700 parts of processed with salt Fructus Psoraleaes.
Embodiment 8
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, add the following component that comprises by weight with each component shown in the embodiment 4: 800 parts of Radix Ginsengs, 100 parts of the Radixs Astragali, 1500 parts of Radix Angelicae Sinensis, 3000 parts of Radix Rehmanniae Preparata, 6000 parts of Radix Aconiti Lateralis Preparata, 750 parts of Cortex Cinnamomis, 3000 parts of Fructus Caryophyllis, 950 parts in processed with salt Fructus Foeniculi, 1200 parts of Radix Achyranthis Bidentataes, 1200 parts of processed with salt Fructus Psoraleaes.
Embodiment 9
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, add the following component that comprises by weight with each component shown in the embodiment 1: 1875 parts of Radix Codonopsis, 750 parts in Poria, 1500 parts of Rhizoma Dioscoreaes, 750 parts of charred Cortex Eucommiaes, 375 parts of Rhizoma Cibotii, 5000 parts of processed with wine Herba Cistanches, 1250 parts of Semen Juglandis, 2000 parts of Herba Epimedii (processed), salt is fried 1250 parts of Semen Astragali Complanatis.
Embodiment 10
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, add the following component that comprises by weight with each component shown in the embodiment 2: 1200 parts of Radix Codonopsis, 1500 parts in Poria, 1500 parts of Rhizoma Dioscoreaes, 300 parts of charred Cortex Eucommiaes, 900 parts of Rhizoma Cibotii, 6500 parts of processed with wine Herba Cistanches, 900 parts of Semen Juglandis, 3500 parts of Herba Epimedii (processed), salt is fried 1200 parts of Semen Astragali Complanatis.
Embodiment 11
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, add the following component that comprises by weight with each component shown in the embodiment 3: 3000 parts of Radix Codonopsis, 1000 parts in Poria, 950 parts of Rhizoma Dioscoreaes, 1200 parts of charred Cortex Eucommiaes, 100 parts of Rhizoma Cibotii, 4500 parts of processed with wine Herba Cistanches, 1700 parts of Semen Juglandis, 2000 parts of Herba Epimedii (processed), salt is fried 900 parts of Semen Astragali Complanatis.
Embodiment 12
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, add the following component that comprises by weight with each component shown in the embodiment 4: 1500 parts of Radix Codonopsis, 500 parts in Poria, 2500 parts of Rhizoma Dioscoreaes, 800 parts of charred Cortex Eucommiaes, 1500 parts of Rhizoma Cibotii, 3000 parts of processed with wine Herba Cistanches, 1200 parts of Semen Juglandis, 900 parts of Herba Epimedii (processed), salt is fried 1700 parts of Semen Astragali Complanatis.
Embodiment 13
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, add the following component that comprises by weight with each component shown in the embodiment 5: 1875 parts of Radix Codonopsis, 750 parts in Poria, 1500 parts of Rhizoma Dioscoreaes, 750 parts of charred Cortex Eucommiaes, 375 parts of Rhizoma Cibotii, 5000 parts of processed with wine Herba Cistanches, 1250 parts of Semen Juglandis, 2000 parts of Herba Epimedii (processed), salt is fried 1250 parts of Semen Astragali Complanatis.
Embodiment 14
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, add the following component that comprises by weight with each component shown in the embodiment 6: 1200 parts of Radix Codonopsis, 1500 parts in Poria, 1500 parts of Rhizoma Dioscoreaes, 300 parts of charred Cortex Eucommiaes, 900 parts of Rhizoma Cibotii, 6500 parts of processed with wine Herba Cistanches, 900 parts of Semen Juglandis, 3500 parts of Herba Epimedii (processed), salt is fried 1200 parts of Semen Astragali Complanatis.
Embodiment 15
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, add the following component that comprises by weight with each component shown in the embodiment 7: 3000 parts of Radix Codonopsis, 1000 parts in Poria, 950 parts of Rhizoma Dioscoreaes, 1200 parts of charred Cortex Eucommiaes, 100 parts of Rhizoma Cibotii, 4500 parts of processed with wine Herba Cistanches, 1700 parts of Semen Juglandis, 2000 parts of Herba Epimedii (processed), salt is fried 900 parts of Semen Astragali Complanatis.
Embodiment 16
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, add the following component that comprises by weight with each component shown in the embodiment 8: 1500 parts of Radix Codonopsis, 500 parts in Poria, 2500 parts of Rhizoma Dioscoreaes, 800 parts of charred Cortex Eucommiaes, 1500 parts of Rhizoma Cibotii, 3000 parts of processed with wine Herba Cistanches, 1200 parts of Semen Juglandis, 900 parts of Herba Epimedii (processed), salt is fried 1700 parts of Semen Astragali Complanatis.
Embodiment 17
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, adds the following component that comprises by weight with each component shown in the embodiment 1: 2000 parts of Fructus Rubies, 750 parts of Fructus Lycii, 750 parts of processed with wine Fructus Schisandrae Chinensis, 1250 parts of Semen Cuscutae, 750 parts of processed with wine Fructus Corni, 625 parts of Os Draconis (calcined)s, 375 parts in Radix Glycyrrhizae.
Embodiment 18
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, adds the following component that comprises by weight with each component shown in the embodiment 2: 3000 parts of Fructus Rubies, 1000 parts of Fructus Lycii, 300 parts of processed with wine Fructus Schisandrae Chinensis, 600 parts of Semen Cuscutae, 1200 parts of processed with wine Fructus Corni, 500 parts of Os Draconis (calcined)s, 900 parts in Radix Glycyrrhizae.
Embodiment 19
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, adds the following component that comprises by weight with each component shown in the embodiment 3: 2000 parts of Fructus Rubies, 500 parts of Fructus Lycii, 800 parts of processed with wine Fructus Schisandrae Chinensis, 1700 parts of Semen Cuscutae, 500 parts of processed with wine Fructus Corni, 250 parts of Os Draconis (calcined)s, 500 parts in Radix Glycyrrhizae.
Embodiment 20
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, adds the following component that comprises by weight with each component shown in the embodiment 4: 1000 parts of Fructus Rubies, 1500 parts of Fructus Lycii, 1200 parts of processed with wine Fructus Schisandrae Chinensis, 1200 parts of Semen Cuscutae, 1800 parts of processed with wine Fructus Corni, 1500 parts of Os Draconis (calcined)s, 100 parts in Radix Glycyrrhizae.
Embodiment 21
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, adds the following component that comprises by weight with each component shown in the embodiment 5: 2000 parts of Fructus Rubies, 750 parts of Fructus Lycii, 750 parts of processed with wine Fructus Schisandrae Chinensis, 1250 parts of Semen Cuscutae, 750 parts of processed with wine Fructus Corni, 625 parts of Os Draconis (calcined)s, 375 parts in Radix Glycyrrhizae.
Embodiment 22
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, adds the following component that comprises by weight with each component shown in the embodiment 6: 3000 parts of Fructus Rubies, 1000 parts of Fructus Lycii, 300 parts of processed with wine Fructus Schisandrae Chinensis, 600 parts of Semen Cuscutae, 1200 parts of processed with wine Fructus Corni, 500 parts of Os Draconis (calcined)s, 900 parts in Radix Glycyrrhizae.
Embodiment 23
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, adds the following component that comprises by weight with each component shown in the embodiment 7: 2000 parts of Fructus Rubies, 500 parts of Fructus Lycii, 800 parts of processed with wine Fructus Schisandrae Chinensis, 1700 parts of Semen Cuscutae, 500 parts of processed with wine Fructus Corni, 250 parts of Os Draconis (calcined)s, 500 parts in Radix Glycyrrhizae.
Embodiment 24
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, adds the following component that comprises by weight with each component shown in the embodiment 8: 1000 parts of Fructus Rubies, 1500 parts of Fructus Lycii, 1200 parts of processed with wine Fructus Schisandrae Chinensis, 1200 parts of Semen Cuscutae, 1800 parts of processed with wine Fructus Corni, 1500 parts of Os Draconis (calcined)s, 100 parts in Radix Glycyrrhizae.
Embodiment 25
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, adds the following component that comprises by weight with each component shown in the embodiment 9: 2000 parts of Fructus Rubies, 750 parts of Fructus Lycii, 750 parts of processed with wine Fructus Schisandrae Chinensis, 1250 parts of Semen Cuscutae, 750 parts of processed with wine Fructus Corni, 625 parts of Os Draconis (calcined)s, 375 parts in Radix Glycyrrhizae.
Embodiment 26
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, adds the following component that comprises by weight with each component shown in the embodiment 10: 3000 parts of Fructus Rubies, 1000 parts of Fructus Lycii, 300 parts of processed with wine Fructus Schisandrae Chinensis, 600 parts of Semen Cuscutae, 1200 parts of processed with wine Fructus Corni, 500 parts of Os Draconis (calcined)s, 900 parts in Radix Glycyrrhizae.
Embodiment 27
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, adds the following component that comprises by weight with each component shown in the embodiment 11: 2000 parts of Fructus Rubies, 500 parts of Fructus Lycii, 800 parts of processed with wine Fructus Schisandrae Chinensis, 1700 parts of Semen Cuscutae, 500 parts of processed with wine Fructus Corni, 250 parts of Os Draconis (calcined)s, 500 parts in Radix Glycyrrhizae.
Embodiment 28
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, adds the following component that comprises by weight with each component shown in the embodiment 12: 1000 parts of Fructus Rubies, 1500 parts of Fructus Lycii, 1200 parts of processed with wine Fructus Schisandrae Chinensis, 1200 parts of Semen Cuscutae, 1800 parts of processed with wine Fructus Corni, 1500 parts of Os Draconis (calcined)s, 100 parts in Radix Glycyrrhizae.
Embodiment 29
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, adds the following component that comprises by weight with each component shown in the embodiment 13: 2000 parts of Fructus Rubies, 750 parts of Fructus Lycii, 750 parts of processed with wine Fructus Schisandrae Chinensis, 1250 parts of Semen Cuscutae, 750 parts of processed with wine Fructus Corni, 625 parts of Os Draconis (calcined)s, 375 parts in Radix Glycyrrhizae.
Embodiment 30
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, adds the following component that comprises by weight with each component shown in the embodiment 14: 3000 parts of Fructus Rubies, 1000 parts of Fructus Lycii, 300 parts of processed with wine Fructus Schisandrae Chinensis, 600 parts of Semen Cuscutae, 1200 parts of processed with wine Fructus Corni, 500 parts of Os Draconis (calcined)s, 900 parts in Radix Glycyrrhizae.
Embodiment 31
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, adds the following component that comprises by weight with each component shown in the embodiment 15: 2000 parts of Fructus Rubies, 500 parts of Fructus Lycii, 800 parts of processed with wine Fructus Schisandrae Chinensis, 1700 parts of Semen Cuscutae, 500 parts of processed with wine Fructus Corni, 250 parts of Os Draconis (calcined)s, 500 parts in Radix Glycyrrhizae.
Embodiment 32
The medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, adds the following component that comprises by weight with each component shown in the embodiment 16: 1000 parts of Fructus Rubies, 1500 parts of Fructus Lycii, 1200 parts of processed with wine Fructus Schisandrae Chinensis, 1200 parts of Semen Cuscutae, 1800 parts of processed with wine Fructus Corni, 1500 parts of Os Draconis (calcined)s, 100 parts in Radix Glycyrrhizae.
Embodiment 33
A kind of enriching yin and nourishing kidney of embodiment 1-embodiment 33 are kept fit the medicine of brain-strengthening and can be made tablet, capsule, powder, pill, drop pill etc. according to a conventional method.
The preparation method of medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, comprises the steps:
(1) take by weighing 1875 parts of Testis et Pentis Canis, 40 parts of Ligamentum cervis take the lead mouth to remove 7500 parts of pawl sparrow meats, 930 parts of Testis Et penis Equi, 500 parts of dried shrimps, 750 parts in Cornu Cervi Pantotrichum, 75 parts of hippocampus 3s, 375 parts of HAIQU, 40 parts of system Os pardis, 240 parts of Geckos, 750 parts of Radix Ginsengs, 625 parts of the Radixs Astragali, 1000 parts of Radix Angelicae Sinensis, 5000 parts of Radix Rehmanniae Preparata, 5000 parts of Radix Aconiti Lateralis Preparata, 375 parts of Cortex Cinnamomis, 2500 parts of Fructus Caryophyllis, 1250 parts in processed with salt Fructus Foeniculi, 750 parts of Radix Achyranthis Bidentataes, 1250 parts of processed with salt Fructus Psoraleaes, 1875 parts of Radix Codonopsis, 750 parts in Poria, 1500 parts of Rhizoma Dioscoreaes, 750 parts of charred Cortex Eucommiaes, 375 parts of Rhizoma Cibotii, 5000 parts of processed with wine Herba Cistanches, 1250 parts of Semen Juglandis, 2000 parts of Herba Epimedii (processed), salt is fried 1250 parts of Semen Astragali Complanatis, 2000 parts of Fructus Rubies, 750 parts of Fructus Lycii, 750 parts of processed with wine Fructus Schisandrae Chinensis, 1250 parts of Semen Cuscutae, 750 parts of processed with wine Fructus Corni, 625 parts of Os Draconis (calcined)s, 375 parts in Radix Glycyrrhizae;
(2) described charred Cortex Eucommiae is ground into powder, it is standby to cross 120 mesh sieves;
(3) with described Radix Rehmanniae Preparata, take the lead to boil 8 times before mouth goes the pawl sparrow meat to add the water of 8 times of weight, boiled 3 hours at every turn, merge decocting liquid, filter, it is 1.5 condensed cream that filtrate is condensed into 50 ℃ of relative densities;
(4) described Testis Et penis Equi, Testis et Pentis Canis, Ligamentum cervi, dried shrimps are added 4000 times of weight yellow wine and put in the container, sealing, steam exhausted by medical material to yellow wine till, take out drying, crushing screening;
(5) with all the other described 29 flavor decoction pieces crushing screenings; Add the powder that described step (4) makes, add the condensed cream that described step (3) makes, add proper honey and water, pill is rushed circle, and drying is with described Cortex Eucommiae powdered carbon coating, polishing, drying, promptly.
Embodiment 34
The preparation method of medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, comprises the steps:
(1) take by weighing 1500 parts of Testis et Pentis Canis, 50 parts of Ligamentum cervis take the lead mouth to remove 9500 parts of pawl sparrow meats, 750 parts of Testis Et penis Equi, 600 parts of dried shrimps, 1200 parts in Cornu Cervi Pantotrichum, 100 parts of Hippocampus, 800 parts of HAIQU, 100 parts of system Os pardis, 100 parts of Geckos, 800 parts of Radix Ginsengs, 1200 parts of the Radixs Astragali, 300 parts of Radix Angelicae Sinensis, 4500 parts of Radix Rehmanniae Preparata, 7000 parts of Radix Aconiti Lateralis Preparata, 200 parts of Cortex Cinnamomis, 3000 parts of Fructus Caryophyllis, 1800 parts in processed with salt Fructus Foeniculi, 300 parts of Radix Achyranthis Bidentataes, 1000 parts of processed with salt Fructus Psoraleaes, 3000 parts of Radix Codonopsis, 500 parts in Poria, 2000 parts of Rhizoma Dioscoreaes, 1200 parts of charred Cortex Eucommiaes, 100 parts of Rhizoma Cibotii, 4500 parts of processed with wine Herba Cistanches, 1700 parts of Semen Juglandis, 900 parts of Herba Epimedii (processed), salt is fried 1200 parts of Semen Astragali Complanatis, 3000 parts of Fructus Rubies, 500 parts of Fructus Lycii, 1000 parts of processed with wine Fructus Schisandrae Chinensis, 1700 parts of Semen Cuscutae, 500 parts of processed with wine Fructus Corni, 1200 parts of Os Draconis (calcined)s, 900 parts in Radix Glycyrrhizae;
(2) described charred Cortex Eucommiae is ground into powder, it is standby to cross 120 mesh sieves;
(3) with described Radix Rehmanniae Preparata, take the lead to boil 3 times before mouth goes the pawl sparrow meat to add the water of 8 times of weight, boiled 2 hours at every turn, merge decocting liquid, filter, it is 1.2 condensed cream that filtrate is condensed into 45 ℃ of relative densities;
(4) described Testis Et penis Equi, Testis et Pentis Canis, Ligamentum cervi, dried shrimps are added 3000 times of weight yellow wine and put in the container, sealing, steam exhausted by medical material to yellow wine till, take out drying, crushing screening;
(5) with all the other described 29 flavor decoction pieces crushing screenings; Add the powder that described step (4) makes, add described step
(3) condensed cream that makes adds proper honey and water, and pill is rushed circle, and drying is with described Cortex Eucommiae powdered carbon coating, polishing, drying, promptly.
Embodiment 35
The preparation method of medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, comprises the steps:
(1) take by weighing 2500 parts of Testis et Pentis Canis, 20 parts of Ligamentum cervis take the lead mouth to remove 6000 parts of pawl sparrow meats, 1100 parts of Testis Et penis Equi, 300 parts of dried shrimps, 8200 parts in Cornu Cervi Pantotrichum, 1500 parts of Hippocampus, 200 parts of HAIQU, 50 parts of system Os pardis, 850 parts of Geckos, 300 parts of Radix Ginsengs, 800 parts of the Radixs Astragali, 1500 parts of Radix Angelicae Sinensis, 3000 parts of Radix Rehmanniae Preparata, 6000 parts of Radix Aconiti Lateralis Preparata, 750 parts of Cortex Cinnamomis, 1500 parts of Fructus Caryophyllis, 1200 parts in processed with salt Fructus Foeniculi, 1200 parts of Radix Achyranthis Bidentataes, 700 parts of processed with salt Fructus Psoraleaes, 2000 parts of Radix Codonopsis, 1500 parts in Poria, 950 parts of Rhizoma Dioscoreaes, 800 parts of charred Cortex Eucommiaes, 1500 parts of Rhizoma Cibotii, 3000 parts of processed with wine Herba Cistanches, 1200 parts of Semen Juglandis, 3500 parts of Herba Epimedii (processed), salt is fried 900 parts of Semen Astragali Complanatis, 2000 parts of Fructus Rubies, 1500 parts of Fructus Lycii, 300 parts of processed with wine Fructus Schisandrae Chinensis, 1200 parts of Semen Cuscutae, 1800 parts of processed with wine Fructus Corni, 250 parts of Os Draconis (calcined)s, 400 parts in Radix Glycyrrhizae;
(2) described charred Cortex Eucommiae is ground into powder, it is standby to cross 120 mesh sieves;
(3) with described Radix Rehmanniae Preparata, take the lead to boil 3 times before mouth goes the pawl sparrow meat to add the water of 5 times of weight, boiled 3 hours at every turn, merge decocting liquid, filter, it is 1.5 condensed cream that filtrate is condensed into 55 ℃ of relative densities;
(4) described Testis Et penis Equi, Testis et Pentis Canis, Ligamentum cervi, dried shrimps are added 5000 times of weight yellow wine and put in the container, sealing, steam exhausted by medical material to yellow wine till, take out drying, crushing screening;
(5) with all the other described 29 flavor decoction pieces crushing screenings; Add the powder that described step (4) makes, add the condensed cream that described step (3) makes, add proper honey and water, pill is rushed circle, and drying is with described Cortex Eucommiae powdered carbon coating, polishing, drying, promptly.
Embodiment 36
The preparation method of medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney, comprises the steps:
(1) take by weighing 2000 parts of Testis et Pentis Canis, 80 parts of Ligamentum cervis take the lead mouth to remove 5500 parts of pawl sparrow meats, 800 parts of Testis Et penis Equi, 900 parts of dried shrimps, 500 parts in Cornu Cervi Pantotrichum, 800 parts of Hippocampus, 1000 parts of HAIQU, 10 parts of system Os pardis, 500 parts of Geckos, 1200 parts of Radix Ginsengs, 100 parts of the Radixs Astragali, 1000 parts of Radix Angelicae Sinensis, 6000 parts of Radix Rehmanniae Preparata, 3500 parts of Radix Aconiti Lateralis Preparata, 500 parts of Cortex Cinnamomis, 4500 parts of Fructus Caryophyllis, 950 parts in processed with salt Fructus Foeniculi, 800 parts of Radix Achyranthis Bidentataes, 1700 parts of processed with salt Fructus Psoraleaes, 3000 parts of Radix Codonopsis, 1100 parts in Poria, 2500 parts of Rhizoma Dioscoreaes, 300 parts of charred Cortex Eucommiaes, 1200 parts of Rhizoma Cibotii, 6500 parts of processed with wine Herba Cistanches, 900 parts of Semen Juglandis, 2000 parts of Herba Epimedii (processed), salt is fried 1700 parts of Semen Astragali Complanatis, 1000 parts of Fructus Rubies, 800 parts of Fructus Lycii, 1200 parts of processed with wine Fructus Schisandrae Chinensis, 600 parts of Semen Cuscutae, 1200 parts of processed with wine Fructus Corni, 1500 parts of Os Draconis (calcined)s, 100 parts in Radix Glycyrrhizae;
(2) described charred Cortex Eucommiae is ground into powder, it is standby to cross 120 mesh sieves;
(3) with described Radix Rehmanniae Preparata, take the lead to boil 2 times before mouth goes the pawl sparrow meat to add the water of 10 times of weight, boiled 5 hours at every turn, merge decocting liquid, filter, it is 1.1 condensed cream that filtrate is condensed into 50 ℃ of relative densities;
(4) described Testis Et penis Equi, Testis et Pentis Canis, Ligamentum cervi, dried shrimps are added 4000 times of weight yellow wine and put in the container, sealing, steam exhausted by medical material to yellow wine till, take out drying, crushing screening;
(5) with all the other described 29 flavor decoction pieces crushing screenings; Add the powder that described step (4) makes, add described step
(3) condensed cream that makes adds proper honey and water, and pill is rushed circle, and drying is with described Cortex Eucommiae powdered carbon coating, polishing, drying, promptly.
Embodiment 37
A kind of enriching yin and nourishing kidney of the embodiment of the invention 33 preparation are kept fit the medicine (concentrated watered pill, the heavily about 270mg of every ball) of brain-strengthening and are pulverized back abundant porphyrize in mortar, add normal saline and are mixed with uniform suspension for irritating stomach usefulness.Laboratory animal mice and rat provide by medical experiment animal development centre, Tianjin.
One. anti-fatigue test
Adopt mice swimming method, use Male Kunming strain mice, body weight 20-22g, be divided into three groups at random, every group of 20 animals, two groups of administration gavage 1g/kg and 2g/kg medicine of the present invention respectively, and matched group gavages the equivalent normal saline, be administered once every day, continuous 21 days, mice put into diameter 15cm, depth of water 20cm in 2 hours after the last administration, in the glass jar that water temperature is 27 ± 1 ℃, every Mus is all at the bear a heavy burden iron hoop of 1/7 body weight of afterbody.Record mice swimming continuance time (from put into the water beginning to unable float till), relatively administration group and right difference the results are shown in Table 1.
Table 1 enriching yin and nourishing kidney are kept fit the medicine of brain-strengthening to the influence of mice swimming time
| Group | Dosage g/kg | Number of animals (only) | Swimming continuance time (branch) X ± SD |
| Small dose group of the present invention | 1 | 20 | 4.38±1.51* |
| The heavy dose of group of the present invention | 2 | 20 | 5.07±1.86* |
| Matched group | 0 | 20 | 2.43±1.15 |
* compare P＜0.05 (down together) with matched group
By finding out that two dosage groups of medicine of the present invention all can obviously improve the swimming ability of mice in the table, point out it can strengthen mice muscle power, antifatigue effect is arranged.
Two. hypoxia endurance test
Get 80 of male mices, body weight 18-22g, be divided into three groups at random, every group of 20 animals, the administration group gavages 1g/kg and 2g/kg medicine of the present invention, and matched group gavaged the normal saline of equivalent after 30 minutes, and mice is put into the airtight wide mouthed bottle of the 125ml that fills sodica calx respectively, the record mouse diing time the results are shown in Table 2.
Table 2 medicine of the present invention is to the influence of anoxia mice life span
| Group | Dosage g/kg | Number of animals (only) | Swimming continuance time (branch) X ± SD |
| Small dose group of the present invention | 1 | 20 | 24.53±2.71* |
| The heavy dose of group of the present invention | 2 | 20 | 26.34±2.55* |
| Matched group | 0 | 20 | 17.50±2.87 |
The result shows that under condition of normal pressure medicine of the present invention can significantly prolong the time-to-live of mice under anoxia condition, with matched group comparing difference remarkable (P＜0.05)
Three. cold test
Get 60 of male mices, body weight 18-22g, be divided into three groups at random, every group of 20 animals gavage 1g/kg and 2g/kg medicine of the present invention two groups of every days of administration, matched group gavages the normal saline of equivalent, continuous 10 days, half an hour after the last administration, put into-4-5 ℃ refrigerator, observed once every 15 minutes, to its death.Calculate the mean survival time of animal, the results are shown in Table 3.Table 3 medicine of the present invention is to the influence of mice life span under the cryogenic conditions
| Group | Dosage g/kg | Number of animals (only) | Swimming continuance time (branch) X ± SD |
| Small dose group of the present invention | 1 | 20 | 3.89±1.18* |
| The heavy dose of group of the present invention | 2 | 20 | 4.67±1.17* |
| Matched group | 0 | 20 | 2.82±0.67 |
The result shows and gavages medicine of the present invention, can prolong the time-to-live of mice under cold environment, illustrates that it has cold-resistant anti-effect of freezing.
Four. high temperature resistant test
Get 45 of male rats, body weight 120-150g is divided into three groups at random, and every group of 15 animals are measured normal rat body temperature earlier before the medication.Two groups of administration gavage pill 0.5g/kg of the present invention and 1g/kg respectively, and matched group gavages the equivalent normal saline.After 30 minutes animal put into 45 ± 2 ℃ calorstat, takes out after 20 minutes, again thermometric once, the record temperature difference the results are shown in Table 4.
Table 4 pill of the present invention is to the influence of rat life span under the hot conditions
| Group | Dosage g/kg | Number of animals (only) | (17 ℃ of room temperatures) body temperature X ± SD before the medication | Incubator (45 ± 2 ℃) baking body temperature X ± SD after 20 minutes | Difference |
| Small dose group of the present invention | 0.5 | 15 | 38.47±0.33 | 40.33±1.90 | 1.86 |
| The heavy dose of group of the present invention | 1 | 15 | 38.21±0,56 | 39.29±0.65 | 1.08 |
| Matched group | 0 | 15 | 37.60±0.60 | 40.51±0.50 | 2.91 |
The result shows that the rat temperature lift-off value that gavages pill of the present invention is lower than matched group, and the heat-resisting ability of rat strengthens behind the display application pill of the present invention.
Five. to the therapeutical effect of " yang deficiency " animal:
The manufacturing of " yang deficiency " animal model, reference literature method (Liu Fuchun etc.: Journal of Traditional Chinese Medicine 16 (2); 66,1985) get 60 of Male Kunming strain mice, body weight 22-25g is divided into four groups at random, every group of 15 animals." yang deficiency " is organized and is gavaged the 375mg/kg hydroxyurea every day, two groups except that giving every day the hydroxyurea, add 1g/kg, 2g/kg pill of the present invention respectively, the normal control group gives the normal saline of equivalent, every day gastric infusion once, amount to 14 days, observe the animal dead situation, body weight change, and after getting mouse spleen, testis and washing repeatedly, blot with filter paper, wet tissue weighs.Compare each group difference.The results are shown in Table 5.
Table 5 pill of the present invention is to the influence of " yang deficiency " mice body weight, spleen, testicular weight
| Group | Dead animal number (only) | Body weight (g) X ± SD before the moulding | Body weight after the moulding (g) X ± SD | Heavy (mg) X ± SD of spleen | Heavy (mg) X ± SD of testis |
| " yang deficiency " group | 2 | 23.3±1.1 | 21.8±0.8* | 93.1±6.9* | 80.9±4.2* |
| Small dose group of the present invention | 0 | 23.9±1.4 | 29.0±0.9△ | 113.2±3.8 △ | 98.4±4.6△ |
| The heavy dose of group of the present invention | 0 | 24.2±1.6 | 29.7±1.1△ | 116.3±6.1 △ | 101.4±6.3 △ |
| Matched group | 0 | 23.5±1.8 | 30.5±1.3 | 118.2±3.8 | 107.7±6.1 |
* compare P＜0.01 with the normal control group; △ compares P＜0.05 with " yang deficiency " group
The result shows in 15 animals of " yang deficiency " group 2 death, the weight saving of body weight and spleen testis, with normal control group comparing difference highly significant P＜0.01, give pill of the present invention none death of animal in 14 days, and the weight of the weight of animals and spleen, testis is close with the normal control group, with the remarkable P of " yang deficiency " group comparing difference＜0.05, illustrate that pill of the present invention has tangible antagonism to " yang deficiency " that hydroxyurea caused.
Brief summary and discussion
More than we have studied the pharmacological action of pill of the present invention, the result shows that it has obvious anti-fatigue, anoxia enduring, low temperature resistant, resistant to elevated temperatures effect, also has the obvious treatment effect to " yang deficiency " animal.The pharmacological action of Yang-strengthening drug is very extensive, the pharmacology of single medicinal materials such as Radix Ginseng, Fructus Lycii, Herba Epimedii has had a large amount of research and argumentation in this medicine prescription, the pharmacological action of compound recipe is similar substantially to the pharmacology of unit medicine, but because the compatibility conspiracy relation between each medicine, the effect of compound recipe should be total embodiment that each drug effect is answered, so make its pharmacologically active more apparent extensively, act on also more obviously, this point also has been described in this experiment.
The traditional Chinese medical science thinks that the essence of " yang deficiency " is deficiency and coldness, main clinic symptoms is an aversion to cold and preference for warmth, extremity are not warm or faint contrary; clear urine in large amounts; thready pulse; light red tongue is fat etc.; the gruel that occurs withering behind the animal applications hydroxyurea is crispaturaed; movable slow these " yang deficiency " performance that waits; particularly immunosuppressant phenomenon and " yang deficiency clinically " the immunologic hypofunction basically identical of patient's performance, there is the people also to find this performance and the nucleic acid metabolism of " yang deficiency " animal simultaneously, especially relevant with the DNA poor metabolism, therefore we think and use hydroxyurea manufacturing " yang deficiency " model that can obviously influence nucleic acid metabolism, and we think and comparatively suit clinical practice.
Our experimental result is consistent with clinical practice, thus for clinical more reasonable, use this medicine safely and effectively foundation be provided.
Embodiment 38
A kind of enriching yin and nourishing kidney of embodiments of the invention 33 preparation are kept fit medicine (concentrated watered pill, the heavily about 270mg of every ball) clinical observation 300 examples of brain-strengthening and are reported (Tianjin hospital combination of Chinese and Western medicine digestive disease researchs department)
One, clinical data: male's 136 examples, women's 164 examples, the oldest 69 years old, minimum 22 years old, 46 years old mean age.
Age cohorts
| Age | 21-30 | 31-40 | 41-50 | 51-60 | More than 60 |
| The example number | 17 | 34 | 126 | 59 | 64 |
Two. the case choice criteria
(1) case source: combination of Chinese and Western medicine outpatient service 203 examples, Integrated TCM ﹠ Western Medicine Dept. ward 97 examples.
(2) seven sick kinds of doctor trained in Western medicine: climacteric syndrome, post-operative recovery, prostate hyperplasia wins hypofunction, neurasthenia, coronary heart disease, diabetes.Above sick the kind shows as clinically: asthenia of both the spleen and kidney; Deficient qi and blood, insufficiency of kidney-YANG, the deficiency of the kidney yin syndrome has more than three main disease and can be decided to be the observation case.
The differential diagnosis in tcm standard
1. asthenia of both the spleen and kidney disease: physical weakness, ache of the spinal column, coldness of the body with chills, spiritlessness and sparing of words, fatigue and asthenia, light red tongue, the fat tender indentation that has, deep-slow pulse or thin and unable.
2. deficient qi and blood disease: shallow complexion, have a dizzy spell shortness of breath and palpitation, spiritlessness and sparing of words, deep-slow pulse or imaginary number, the light few tongue of tongue.
3. deficiency of kidney-YANG syndrome: impotence and premature ejaculation, libido is indifferent, soreness of the waist and knees, aversion to cold and preference for warmth, the fat tongue of light red tongue is white, a little less than the deep-thready pulse.
4. kidney yin deficient syndrome: the seminal emission dream is let out, dysphoria with feverish sensation in the chest palms and soles, heel pain, dizziness and tinnitus, night sweat xerostomia, the few tongue of red tongue, thready and rapid pulse.
Seven kinds of disease traditional Chinese medical science typings
| The example number | Asthenia of both the spleen and kidney example % | Deficient qi and blood % | Insufficiency of kidney-YANG example % | Deficiency of the kidney yin example % | |
| Climacteric | 77 | 14(18.18) | 8(10.39) | 15(19.48) | 40(51.95) |
| The post-operative recovery phase | 57 | 20(35.09) | 31(54.38) | 2(3.51) | 4(7.02) |
| Prostate hyperplasia | 44 | 7(15.19) | 5(11.36) | 27(61.36) | 5(11.36) |
| Sexual disorder | 36 | 3(8.33) | 6(16.66) | 22(61.66) | 5(13.89) |
| Coronary heart disease | 37 | 6(16.21) | 5(13.15) | 20(54.05) | 6(16.21) |
| The neurasthenia | 25 | 8(32.00) | 7(28.00) | 6(24.00) | 4(16.00) |
| Diabetes | 24 | 9(37.50) | 4(16.66) | 2(8.33) | 9(37.50) |
| Meter | 300 | 67(22.33) | 66(22.00) | 94(31.33) | 73(24.33) |
Therapeutic Method: this group patient carries out tcm diagnosis and typing by special doctor in outpatient service and ward, filling out patient main suit and clinical examination and laboratory strictly according to the facts by the form requirement reports the result, to meeting the observation case, take concentrated pill of the present invention, each 10, be a course of treatment at twice, three month every day, whenever take medicine two all further consultations once, the doctor that sees patients in time fills in every observation index.Period in a medicine, patient can not take other similar Chinese patent medicine or decoction, and must adhere to taking medicine, and the time of reaching examines, and accurate state of an illness data is provided and accepts relevant biochemical analysis.
Main contents during the doctor must fill up a form strictly according to the facts during further consultation, the imperfect person of acquaintance form's lattice does not do statistics.
Curative effect judging standard
Cure: cardinal symptom all disappears, and it is normal that the tongue arteries and veins recovers, and main related biochemical indicator recovers normal substantially.
Produce effects: cardinal symptom is significantly improved, improvement degree (+++→+) more than secondary, and main related biochemical indicator takes a turn for the better to some extent.
Effectively: cardinal symptom is improved more than one-level (+++→ ++) or (++ →+) main index of correlation and is changed little relatively.
Invalid: each disease does not have improvement, the biochemical indicator no change.
Therapeutic outcome: through nearly one-year age, 374 routine patients are carried out pill clinical observation on the therapeutic effect of the present invention, intact to data
Whole satisfactory 300 routine patients have carried out the curative effect statistics, the results are shown in following table
TCM Syndrome Type and curative effect
Pill of the present invention as can be seen from the above table all has curative effect preferably to above TCM Syndrome Type, and total effective rate reaches 94%.。
| Typing | The example number | Cure rate % | Obvious effective rate % | Effective routine % | Inefficiency % |
| Asthenia of both the spleen and kidney | 67 | 12(17.91) | 24(35.82) | 27(40.29) | 4(5.97) |
| Deficient qi and blood | 66 | 15(22.72) | 26(39.39) | 19(28.79) | 6(9.09) |
| Insufficiency of kidney-YANG | 94 | 37(39.36) | 29(30.85) | 25(26.59) | 3(3.19) |
| Deficiency of the kidney yin | 73 | 21(28.76) | 28(38.35) | 19(26.03) | 5(6.85) |
| Meter | 300 | 85(28.33) | 107(35.67) | 90(30.00) | 18(6.00) |
Its curative effect of statistics saw the following form after seven kinds of diseases of this group were taken pill of the present invention.
| The example number | Cure rate % | Obvious effective rate % | Effective routine % | Inefficiency % | |
| Climacteric | 77 | 25(32.47) | 42(54.55) | 10(12.98) | 0 |
| The post-operative recovery phase | 57 | 15(26.31) | 38(66.67) | 4(7.02) | 0 |
| Prostate hyperplasia | 44 | 18(40.91) | 10(22.72) | 10(22.72) | 6(13.64) |
| Sexual disorder | 36 | 12(33.33) | 9(25.00) | 10(27.78) | 5(13.89) |
| Coronary heart disease | 37 | 6(16.22) | 2(5.40) | 26(70.27) | 3(8.11) |
| The neurasthenia | 25 | 6(24.00) | 4(16.00) | 14(56.00) | 1(4.00) |
| Diabetes | 24 | 3(12.50) | 2(8.33) | 16(66.67) | 3(12.50) |
| Meter | 300 | 85(28.33) | 107(35.67) | 90(30.00) | 18(6.00) |
From last table, add up pill of the present invention as can be seen to climacteric syndrome, prostate hyperplasia, patients such as the patient of various post-operative recoveries and sexual disorder have obvious curative effects, and coronary heart disease, diabetes, patient neurasthenia are also had certain curative effect.
Brief summary: medicine of the present invention has reinforcing the kidney and supporting YANG, YIN nourishing and the production of body fluid promoting, vigorate qi and replenish the blood, the effect of tranquillizing the mind by relieving convulsion, its property of medicine flat as, confirm to deficiency of kidney-QI deficiency of the kidney through clinical observation on the therapeutic effect, deficiency of both QI and blood, diseases such as asthenia of both the spleen and kidney are particularly to insufficiency of kidney-YANG weak person better efficacy.
Motherland's medical science is thought kidney controlling essence storage, and kidney can activating QI, and kidney essense fills that then kidney qi is prosperous, and insufficiency of kidney-YANG then can not be given birth to marrow and be filled bone and support brain, and deficiency of kidney-essence is the bone marrow inanition then, waist is a house of kidney, and soreness of the waist and knees appears in Gu Er, talalgia, damage of kidney-YIN, the disturbance of deficiency-heat inside the body dream of then passing out semen is let out, feverish sensation in the palms and soles, and red tongue with a little fluid is quenched one's thirst.Insufficiency of kidney-YANG then can not replenishing vital QI with drugs of warm nature spleen sun, and indigestion and loss of appetite loose stool appears in dysfunction of the spleen in transportation, and instability of kidney QI is the urinary bladder being out of control then, and envelope is hidden the controlling nocturnal emission with astringent drugs dereliction of duty, clear urine in large amounts occurs, the enuresis, and the spermatorrhea premature ejaculation, deficiency of kidney-QI then sunlight can not reach the flesh table, thereby the loose stool, coldness of the body with chills, lassitude loin and legs.Deficiency of heart-QI is flaccidity of the heart-yang then, agitates unablely, and QI and blood can not normally be moved, deficiency of heart-blood, blood failing to tonify the heart, god becomes homeless to hide and severe palpitation occurs, and is forgetful, and blood deficiency can not be moistened a foster body, upward honor is then had a dizzy spell in face, shallow complexion, deficiency of both QI and blood, the lazy speech of breathing hard, fatigue and weakness.
Motherland's medical science think " nourish heart not from reinforcing the heart, spleen invigorating is from QI invigorating, the QI and blood abundance, ataraxia, spleen must be good for fortune.Analyze Hippocampus the kidney invigorating ball prescription, Fang Zhongyong Hippocampus, Cornu Cervi Pantotrichum. Fructus Psoraleae, Testis et penis callorhini etc. is intended to kidney tonifying, essence replenishing, bone and muscle strengthening, invigorating kidney-YANG is used Radix Ginseng in the side, the Radix Astragali, Arillus Longan, Os Draconis air making-up and spleen enlivening, nourishing blood to tranquillize the mind, to help YIN nourishing such as Radix Rehmanniae Preparata, Radix Angelicae Sinensis, Fructus Lycii and increase liquid. beneficial essence is enriched blood, and is aided with Semen Persicae, Gecko lung benefiting improving inspiration by invigorating kidney-QI Dingchuan again.Note yin yang complementarity, the mutual reason of root in the prescription, noted YIN nourishing, cloudy De Yangsheng in the YANG invigorating, positive cloudy helping, the mutual compatibility of the medicine of negative and positive brings out the best in each other, as seen prescription of the present invention rigorous, medication superior, thus the clinical weakness of the spleen and kidney that is used for, deficiency of both QI and blood, insufficiency of kidney-YANG, the patient of deficiency of the kidney yin often goes smoothly, and effect is remarkable.
Modern medicine study shows, Radix Ginseng in the prescription, and tonics such as the Radix Astragali have the enhancing immune function of human body, comprise cellular immunization and humoral immunization, improve non-specific immunity, and multiple pathogenic bacteria is had inhibitory action.Radix Ginseng, the Radix Astragali, Radix Angelicae Sinensis etc. have the effect that increases cell viability in the experimentation proof side, so can life lengthening, Gecko, Cornu Cervi Pantotrichum, Hippocampus, Testis et penis callorhini also have tangible hormone-like effect and antitumor action in the side, suppress tumour cell division, experimentation also proves, Fructus Psoraleae, Radix Ginseng, the Radix Astragali, Fructus Lycii etc. also have the effect of coronary artery dilator, heart tonifying, diuresis, blood fat reducing, blood sugar lowering, adjusting vegetative nerve function, so the present invention is to climacteric syndrome, the neurasthenia, coronary heart disease, diabetes have better curative effect.
Model case is introduced
Patient male .65 year, teacher, admission number 123482, main cause shortness of breath and palpitation, hypodynamia and amnesia, inappetence, nocturnal emission frequent micturition, the Integrated TCM ﹠ Western Medicine Dept. of being admitted to hospital.
Corpse or other object for laboratory examination and chemical testing shallow complexion, ordinary circumstance is poor, and the rhythm of the heart is neat, and hear sounds is blunt, pulse 90 times/minute, pale tongue with white fur, deep,thready and forceless pulse, diagnosis of coronary heart disease, spleen kidney both deficiency type is given pill of the present invention, each 10, at twice, one month every day, subjective symptoms was clearly better, and appetite heightens, and urine is normal.All diseases disappear substantially after three months, have rosy cheeks, and memory improves, and recovery from illness is left hospital.
Patient women, 51 years old, cadre, admission number 123586, the main cause shortness of breath and palpitation, soreness of the waist and knees, aversion to cold and preference for warmth, unconsciously sweat and tire, the fat tongue of light red tongue is white, deep-thready pulse, and B ultrasonic liver spleen is normal, live Integrated TCM ﹠ Western Medicine Dept., the diagnosis climacteric syndrome, kidney yang deficiency syndrome is given pill of the present invention, each 10, at twice, one month every day, subjective symptoms was clearly better, energy is more preceding abundant, and appetite increases, and the disappearance of all diseases is fully recovered and left hospital after three months.
Embodiment 39
A kind of enriching yin and nourishing kidney of embodiments of the invention 1 preparation are kept fit medicine (concentrated watered pill, the heavily about 270mg of every ball) clinical observation 100 examples of brain-strengthening and are reported (Tianjin hospital combination of Chinese and Western medicine digestive disease researchs department)
Clinical data: male's 50 examples, women's 50 examples, the oldest 61 years old, minimum 23 years old.Case source: combination of Chinese and Western medicine outpatient service 100 examples.Seven sick kinds of doctor trained in Western medicine: climacteric syndrome, post-operative recovery, prostate hyperplasia wins hypofunction, neurasthenia, coronary heart disease, diabetes.Above sick the kind shows as clinically: asthenia of both the spleen and kidney; Deficient qi and blood, insufficiency of kidney-YANG, the deficiency of the kidney yin syndrome has more than three main disease and can be decided to be the observation case.
Seven kinds of disease traditional Chinese medical science typings
| The example number | Asthenia of both the spleen and kidney example % | Deficient qi and blood % | Insufficiency of kidney-YANG example % | Deficiency of the kidney yin example % | |
| Climacteric | 17 | 5(29.41) | 2(11.76) | 6(35.29) | 4(23.54) |
| The post-operative recovery phase | 12 | 2(16.67) | 6(50.00) | 2(16.67) | 2(16.66) |
| Prostate hyperplasia | 14 | 3(15.19) | 2(11.36) | 5(61.36) | 4(11.36) |
| Sexual disorder | 13 | 3(23.08) | 2(15.38) | 3(23.08) | 5(38.46) |
| Coronary heart disease | 16 | 6(37.50) | 2(12.50) | 6(37.50) | 2(12.50) |
| The neurasthenia | 18 | 3(16.67) | 7(38.89) | 4(22.22) | 4(22.22) |
| Diabetes | 10 | 2(20.00) | 4(40.00) | 2(20.00) | 2(20.00) |
| Meter | 100 | 24(22.33) | 25(22.00) | 28(31.33) | 23(24.33) |
Therapeutic Method, curative effect judging standard are with embodiment 38.
Therapeutic outcome:
| Typing | The example number | Cure rate % | Obvious effective rate % | Effective routine % | Inefficiency % |
| Asthenia of both the spleen and kidney | 24 | 4(16.67) | 8(33.33) | 9(37.50) | 3(12.50) |
| Deficient qi and blood | 25 | 5(20.00) | 7(28.00) | 7(28.00) | 6(24.00) |
| Insufficiency of kidney-YANG | 28 | 7(25.00) | 8(28.57) | 8(28.57) | 5(17.86) |
| Deficiency of the kidney yin | 23 | 5(21.74) | 7(30.43) | 6(26.09) | 5(21.74) |
| Meter | 100 | 21(21.00) | 30(30.00) | 30(30.00) | 19(19.00) |
Pill of the present invention as can be seen from the above table all has curative effect preferably to above TCM Syndrome Type
Its curative effect of statistics saw the following form after seven kinds of diseases of this group were taken pill of the present invention.
| The example number | Cure rate % | Obvious effective rate % | Effective routine % | Inefficiency % | |
| Climacteric | 17 | 4(23.53) | 9(52.94) | 3(17.65) | 1(5.88) |
| The post-operative recovery phase | 12 | 3(25.00) | 7(58.33) | 2(16.67) | 0 |
| Prostate hyperplasia | 14 | 3(21.43) | 3(21.43) | 3(21.43) | 5(35.71) |
| Sexual disorder | 13 | 4(30.77) | 3(23.08) | 3(23.08) | 3(23.08) |
| Coronary heart disease | 16 | 2(12.50) | 1(6.25) | 6(37.50) | 7(43.75) |
| The neurasthenia | 18 | 3(16.67) | 2(11.11) | 7(38.89) | 6(33.33) |
| Diabetes | 10 | 2(20.00) | 1(10.00) | 5(50.00) | 2(20.00) |
| Meter | 100 | 21(21.00) | 26(26.00) | 29(29.00) | 24(24.00) |
From last table, add up pill of the present invention as can be seen to climacteric syndrome, prostate hyperplasia, patients such as the patient of various post-operative recoveries and sexual disorder have obvious curative effects, and coronary heart disease, diabetes, patient neurasthenia are also had certain curative effect.
Embodiment 40
A kind of enriching yin and nourishing kidney of embodiments of the invention 5 preparation are kept fit medicine (concentrated watered pill, the heavily about 270mg of every ball) clinical observation 100 examples of brain-strengthening and are reported (Tianjin hospital combination of Chinese and Western medicine digestive disease researchs department)
Clinical data: male's 50 examples, women's 50 examples, the oldest 72 years old, minimum 22 years old.
Case source: combination of Chinese and Western medicine outpatient service 100 examples.
Seven sick kinds of doctor trained in Western medicine: climacteric syndrome, post-operative recovery, prostate hyperplasia wins hypofunction, neurasthenia, coronary heart disease, diabetes.Above sick the kind shows as clinically: asthenia of both the spleen and kidney; Deficient qi and blood, insufficiency of kidney-YANG, the deficiency of the kidney yin syndrome has more than three main disease and can be decided to be the observation case.
Seven kinds of disease traditional Chinese medical science typings
| The example number | Asthenia of both the spleen and kidney example % | Deficient qi and blood % | Insufficiency of kidney-YANG example % | Deficiency of the kidney yin example % | |
| Climacteric | 11 | 5(45.45) | 3(27.27) | 1(9.09) | 2(18.18) |
| The post-operative recovery phase | 36 | 10(27.78) | 13(36.11) | 6(16.67) | 7(19.44) |
| Prostate hyperplasia | 8 | 2(25.00) | 2(25.00) | 2(25.00) | 2(25.00) |
| Sexual disorder | 10 | 3(30.00) | 3(30.00) | 2(20.00) | 2(20.00) |
| Coronary heart disease | 19 | 6(31.58) | 5(26.32) | 5(26.32) | 3(15.79) |
| The neurasthenia | 9 | 3(33.33) | 2(22.22) | 2(22.22) | 2(22.22) |
| Diabetes | 7 | 2(28.57) | 2(28.57) | 1(14.29) | 2(28.57) |
| Meter | 100 | 31(31.00) | 30(30.00) | 19(19.00) | 20(20.00) |
Therapeutic Method, curative effect judging standard are with embodiment 38.
Therapeutic outcome:
| Typing | The example number | Cure rate % | Obvious effective rate % | Effective routine % | Inefficiency % |
| Asthenia of both the spleen and kidney | 31 | 5(16.13) | 11(35.48) | 14(45.16) | 1(3.23) |
| Deficient qi and blood | 30 | 6(20.00) | 12(40.00) | 10(33.33) | 2(6.67) |
| Insufficiency of kidney-YANG | 19 | 4(21.05) | 6(31.58) | 7(36.84) | 2(10.53) |
| Deficiency of the kidney yin | 20 | 4(20.00) | 7(35.00) | 6(30.00) | 3(15.00) |
| Meter | 100 | 19(19.00) | 36(36.00) | 37(37.00) | 8(8.00) |
Pill of the present invention as can be seen from the above table all has curative effect preferably to above TCM Syndrome Type
Its curative effect of statistics saw the following form after seven kinds of diseases of this group were taken pill of the present invention.
| The example number | Cure rate % | Obvious effective rate % | Effective routine % | Inefficiency % | |
| Climacteric | 11 | 3(27.27) | 4(36.36) | 3(27.27) | 1(9.09) |
| The post-operative recovery phase | 36 | 8(22.22) | 25(69.44) | 3(8.33) | 0 |
| Prostate hyperplasia | 8 | 3(37.50) | 2(25.00) | 2(25.00) | 1(12.50) |
| Sexual disorder | 10 | 3(30.00) | 2(20.00) | 3(30.00) | 2(20.00) |
| Coronary heart disease | 19 | 3(15.79) | 1(5.26) | 14(73.68) | 1(5.26) |
| The neurasthenia | 9 | 1(11.11) | 1(11.11) | 5(55.56) | 2(22.22) |
| Diabetes | 7 | 1(14.29) | 1(14.29) | 3(42.86) | 2(28.57) |
| Meter | 100 | 22(22.00) | 36(36.00) | 33(33.00) | 9(9.00) |
From last table, add up pill of the present invention as can be seen to climacteric syndrome, prostate hyperplasia, patients such as the patient of various post-operative recoveries and sexual disorder have obvious curative effects, and coronary heart disease, diabetes, patient neurasthenia are also had certain curative effect.
Embodiment 41
A kind of enriching yin and nourishing kidney of embodiments of the invention 9 preparation are kept fit medicine (concentrated watered pill, the heavily about 270mg of every ball) clinical observation 100 examples of brain-strengthening and are reported (Tianjin hospital combination of Chinese and Western medicine digestive disease researchs department)
Clinical data: male's 50 examples, women surname 50 examples, the oldest 68 years old, minimum 23 years old.
Case source: combination of Chinese and Western medicine outpatient service 100 examples.
Seven sick kinds of doctor trained in Western medicine: climacteric syndrome, post-operative recovery, prostate hyperplasia wins hypofunction, neurasthenia, coronary heart disease, diabetes.Above sick the kind shows as clinically: asthenia of both the spleen and kidney; Deficient qi and blood, insufficiency of kidney-YANG, the deficiency of the kidney yin syndrome has more than three main disease and can be decided to be the observation case.
Seven kinds of disease traditional Chinese medical science typings
| The example number | Asthenia of both the spleen and kidney example % | Deficient qi and blood % | Insufficiency of kidney-YANG example % | Deficiency of the kidney yin example % | |
| Climacteric | 33 | 10(30.30) | 6(18.18) | 11(33.33) | 6(18.18) |
| The post-operative recovery phase | 16 | 5(31.25) | 4(25.00) | 4(25.00) | 3(18.87) |
| Prostate hyperplasia | 6 | 2(33.33) | 1(16.67) | 1(16.67) | 2(33.33) |
| Sexual disorder | 7 | 2(28.57) | 1(14.29) | 2(28.57) | 2(28.57) |
| Coronary heart disease | 22 | 6(27.27) | 4(18.18) | 6(27.27) | 6(27.27) |
| The neurasthenia | 6 | 2(33.33) | 1(16.67) | 1(16.67) | 2(33.33) |
| Diabetes | 10 | 3(30.00) | 2(20.00) | 2(20.00) | 3(30.00) |
| Meter | 100 | 30(30.00) | 19(19.00) | 27(27.00) | 24(24.00) |
Therapeutic Method, curative effect judging standard are with embodiment 38.
Therapeutic outcome:
| Typing | The example number | Cure rate % | Obvious effective rate % | Effective routine % | Inefficiency % |
| Asthenia of both the spleen and kidney | 30 | 4(13.33) | 10(33.33) | 14(46.67) | 2(6.67) |
| Deficient qi and blood | 19 | 3(15.79) | 9(47.37) | 5(26.32) | 2(10.53) |
| Insufficiency of kidney-YANG | 27 | 5(18.52) | 10(37.04) | 10(37.04) | 2(7.41) |
| Deficiency of the kidney yin | 24 | 7(29.17) | 10(41.67) | 5(20.83) | 2(8.33) |
| Meter | 100 | 19(19.00) | 39(39.00) | 34(34.00) | 8(8.00) |
Pill of the present invention as can be seen from the above table all has curative effect preferably to above TCM Syndrome Type
Its curative effect of statistics saw the following form after seven kinds of diseases of this group were taken pill of the present invention.
| The example number | Cure rate % | Obvious effective rate % | Effective routine % | Inefficiency % | |
| Climacteric | 33 | 8(24.24) | 17(51.52) | 7(21.21) | 1(3.03) |
| The post-operative recovery phase | 16 | 6(37.50) | 8(50.00) | 2(12.50) | 0 |
| Prostate hyperplasia | 6 | 1(16.67) | 2(33.33) | 2(33.33) | 1(16.67) |
| Sexual disorder | 7 | 2(28.57) | 2(28.57) | 2(28.57) | 1(14.29) |
| Coronary heart disease | 22 | 5(22.73) | 3(13.64) | 12(54.55) | 2(9.09) |
| The neurasthenia | 6 | 1(16.67) | 1(16.67) | 3(50.00) | 1(16.67) |
| Diabetes | 10 | 2(20.00) | 1(10.00) | 6(60.00) | 1(10.00) |
| Meter | 100 | 25(25.00) | 34(34.00) | 34(34.00) | 7(7.00) |
From last table, add up pill of the present invention as can be seen to climacteric syndrome, prostate hyperplasia, patients such as the patient of various post-operative recoveries and sexual disorder have obvious curative effects, and coronary heart disease, diabetes, patient neurasthenia are also had certain curative effect.
Embodiment 42
A kind of enriching yin and nourishing kidney of embodiments of the invention 13 preparation are kept fit medicine (concentrated watered pill, the heavily about 270mg of every ball) clinical observation 100 examples of brain-strengthening and are reported (Tianjin hospital combination of Chinese and Western medicine digestive disease researchs department)
Clinical data: male's 50 examples, women surname 50 examples, the oldest 69 years old, minimum 20 years old.
Case source: combination of Chinese and Western medicine outpatient service 100 examples.
Seven sick kinds of doctor trained in Western medicine: climacteric syndrome, post-operative recovery, prostate hyperplasia wins hypofunction, neurasthenia, coronary heart disease, diabetes.Above sick the kind shows as clinically: asthenia of both the spleen and kidney; Deficient qi and blood, insufficiency of kidney-YANG, the deficiency of the kidney yin syndrome has more than three main disease and can be decided to be the observation case.
Seven kinds of disease traditional Chinese medical science typings
| The example number | Asthenia of both the spleen and kidney example % | Deficient qi and blood % | Insufficiency of kidney-YANG example % | Deficiency of the kidney yin example % | |
| Climacteric | 24 | 12(50.00) | 4(17.39) | 4(17.39) | 4(17.39) |
| The post-operative recovery phase | 9 | 3(33.33) | 2(22.22) | 2(22.22) | 2(22.22) |
| Prostate hyperplasia | 27 | 10(37.04) | 7(25.93) | 5(18.52) | 5(18.52) |
| Sexual disorder | 12 | 4(33.33) | 3(25.00) | 2(16.67) | 3(25.00) |
| Coronary heart disease | 10 | 3(30.00) | 2(20.00) | 3(30.00) | 2(20.00) |
| The neurasthenia | 9 | 3(33.33) | 2(22.22) | 2(22.22) | 2(22.22) |
| Diabetes | 9 | 2(22.22) | 2(22.22) | 3(33.33) | 2(22.22) |
| Meter | 100 | 37(37.00) | 22(22.00) | 21(21.00) | 20(20.00) |
Therapeutic Method, curative effect judging standard are with embodiment 38.
Therapeutic outcome:
| Typing | The example number | Cure rate % | Obvious effective rate % 1 | Effective routine % | Inefficiency % |
| Asthenia of both the spleen and kidney | 37 | 9(24.32) | 12(32.43) | 15(40.54) | 1(2.70) |
| Deficient qi and blood | 22 | 5(22.73) | 9(40.91) | 7(31.82) | 1(4.55) |
| Insufficiency of kidney-YANG | 21 | 4(19.05) | 9(42.86) | 7(33.33) | 1(4.76) |
| Deficiency of the kidney yin | 20 | 4(29.17) | 8(40.00) | 6(30.00) | 2(10.00) |
| Meter | 100 | 22(20.00) | 38(38.00) | 35(35.00) | 5(5.00) |
Pill of the present invention as can be seen from the above table all has curative effect preferably to above TCM Syndrome Type
Its curative effect of statistics saw the following form after seven kinds of diseases of this group were taken pill of the present invention.
| The example number | Cure rate % | Obvious effective rate % | Effective routine % | Inefficiency % | |
| Climacteric | 24 | 8(33.33) | 12(50.00) | 4(16.67) | 0(0) |
| The post-operative recovery phase | 9 | 2(22.22) | 5(55.56) | 1(11.11) | 1(11.11) |
| Prostate hyperplasia | 27 | 7(25.93) | 9(33.33) | 9(33.33) | 2(7.41) |
| Sexual disorder | 12 | 2(16.67) | 5(41.67) | 4(33.33) | 1(8.33) |
| Coronary heart disease | 10 | 3(30.00) | 2(20.00) | 4(40.00) | 1(10.00) |
| The neurasthenia | 9 | 3(33.33) | 1(11.11) | 4(44.44) | 1(11.11) |
| Diabetes | 9 | 2(22.22) | 2(22.22) | 4(44.44) | 1(11.11) |
| Meter | 100 | 27(27.00) | 36(34.00) | 30(30.00) | 7(7.00) |
From last table, add up pill of the present invention as can be seen to climacteric syndrome, prostate hyperplasia, patients such as the patient of various post-operative recoveries and sexual disorder have obvious curative effects, and coronary heart disease, diabetes, patient neurasthenia are also had certain curative effect.
Embodiment 43
A kind of enriching yin and nourishing kidney of embodiments of the invention 17 preparation are kept fit medicine (concentrated watered pill, the heavily about 270mg of every ball) clinical observation 100 examples of brain-strengthening and are reported (Tianjin hospital combination of Chinese and Western medicine digestive disease researchs department)
Clinical data: male's 50 examples, women's 50 examples, the oldest 69 years old, minimum 20 years old.
Case source: combination of Chinese and Western medicine outpatient service 100 examples.
Seven sick kinds of doctor trained in Western medicine: climacteric syndrome, post-operative recovery, prostate hyperplasia wins hypofunction, neurasthenia, coronary heart disease, diabetes.Above sick the kind shows as clinically: asthenia of both the spleen and kidney; Deficient qi and blood, insufficiency of kidney-YANG, the deficiency of the kidney yin syndrome has more than three main disease and can be decided to be the observation case.
Seven kinds of disease traditional Chinese medical science typings
| The example number | Asthenia of both the spleen and kidney example % | Deficient qi and blood % | Insufficiency of kidney-YANG example % | Deficiency of the kidney yin example % | |
| Climacteric | 23 | 3(13.04) | 4(17.39) | 10(43.48) | 6(26.09) |
| The post-operative recovery phase | 8 | 2(25.00) | 2(25.00) | 2(25.00) | 2(25.00) |
| Prostate hyperplasia | 21 | 5(23.81) | 5(23.81) | 6(28.57) | 5(23.81) |
| Sexual function is low | 20 | 5(25.00) | 5(25.00) | 6(30.00) | 4(20.00) |
| Coronary heart disease | 12 | 3(25.00) | 3(25.00) | 3(25.00) | 3(25.00) |
| The neurasthenia | 10 | 3(30.00) | 2(20.00) | 3(30.00) | 2(20.00) |
| Diabetes | 6 | 2(33.33) | 1(16.67) | 2(33.33) | 1(16.67) |
| Meter | 100 | 23(23.00) | 22(22.00) | 32(32.00) | 23(23.00) |
Therapeutic Method, curative effect judging standard are with embodiment 38.
Therapeutic outcome:
| Typing | The example number | Cure rate % | Obvious effective rate % | Effective routine % | Inefficiency % |
| Asthenia of both the spleen and kidney | 23 | 5(21.74) | 7(30.43) | 10(43.48) | 1(4.35) |
| Deficient qi and blood | 22 | 5(22.73) | 9(40.91) | 7(31.82) | 1(4.55) |
| Insufficiency of kidney-YANG | 32 | 10(31.25) | 12(37.50) | 9(28.13) | 1(3.13) |
| Deficiency of the kidney yin | 23 | 7(30.43) | 9(39.13) | 5(21.74) | 2(8.70) |
| Meter | 100 | 27(27.00) | 37(37.00) | 31(31.00) | 5(5.00) |
Pill of the present invention as can be seen from the above table all has curative effect preferably to above TCM Syndrome Type
Its curative effect of statistics saw the following form after seven kinds of diseases of this group were taken pill of the present invention.
| The example number | Cure rate % | Obvious effective rate % | Effective routine % | Inefficiency % | |
| Climacteric | 23 | 6(26.09) | 11(47.83) | 5(21.74) | 1(4.35) |
| The post-operative recovery phase | 8 | 1(12.50) | 3(37.50) | 2(25.00) | 2(25.00) |
| Prostate hyperplasia | 21 | 5(23.81) | 7(33.33) | 7(33.33) | 2(9.52) |
| Sexual disorder | 20 | 5(25.00) | 6(30.00) | 8(40.00) | 1(5.00) |
| Coronary heart disease | 12 | 3(25.00) | 2(16.67) | 6(50.00) | 1(8.33) |
| The neurasthenia | 10 | 2(20.00) | 2(20.00) | 5(50.00) | 1(10.00) |
| Diabetes | 6 | 1(16.67) | 1(16.67) | 3(50.00) | 1(16.67) |
| Meter | 100 | 23(23.00) | 32(32.00) | 36(36.00) | 9(9.00) |
From last table, add up pill of the present invention as can be seen to climacteric syndrome, prostate hyperplasia, patients such as the patient of various post-operative recoveries and sexual disorder have obvious curative effects, and coronary heart disease, diabetes, patient neurasthenia are also had certain curative effect.
Embodiment 44
A kind of enriching yin and nourishing kidney of embodiment 1-embodiment 33 are kept fit the medicine of brain-strengthening and can be made tablet, capsule, powder, pill, drop pill etc. according to a conventional method.
Claims (10)
1. the medicine of brain-strengthening is kept fit in enriching yin and nourishing kidney, it is characterized in that comprising by weight following component: Testis et Pentis Canis 1500-2500 part, Ligamentum cervi 20-80 part is taken the lead mouth to go pawl sparrow meat 5500-9500 part, Testis Et penis Equi 750-1100 part, dried shrimps 300-900 part, Cornu Cervi Pantotrichum 500-1200 part, Hippocampus 100-1500 part, HAIQU 200-1000 part, system Os pardi 10-100 part, Gecko 100-850 part.
2. the medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney according to claim 1, it is characterized in that described Testis et Pentis Canis is 1875 parts, described Ligamentum cervi is 40 parts, describedly takes the lead mouth to remove the pawl sparrow meat be 7500 parts, and described Testis Et penis Equi is 930 parts, described dried shrimps is 500 parts, described Cornu Cervi Pantotrichum is 750 parts, and described Hippocampus is 375 parts, and described HAIQU is 375 parts, described system Os pardi is 40 parts, and described Gecko is 240 parts.
3. the medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney according to claim 1, it is characterized in that comprising by weight: Radix Ginseng 300-1200 part, Radix Astragali 100-1200 part, Radix Angelicae Sinensis 300-1500 part, Radix Rehmanniae Preparata 3000-6000 part, Radix Aconiti Lateralis Preparata 3500-7000 part, Cortex Cinnamomi 200-750 part, Fructus Caryophylli 1500-4500 part, processed with salt Fructus Foeniculi 950-1800 part, Radix Achyranthis Bidentatae 300-1200 part, processed with salt Fructus Psoraleae 700-1700 part.
4. the medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney according to claim 3, it is characterized in that described Radix Ginseng is 750 parts, the described Radix Astragali is 625 parts, and described when being classified as 1000 parts, described Radix Rehmanniae Preparata is 5000 parts, described Radix Aconiti Lateralis Preparata is 5000 parts, described Cortex Cinnamomi is 375 parts, and described Fructus Caryophylli is 2500 parts, and described processed with salt Fructus Foeniculi is 1250 parts, described Radix Achyranthis Bidentatae is 750 parts, and described processed with salt Fructus Psoraleae is 1250 parts.
5. the medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney according to claim 1, it is characterized in that comprising by weight: Radix Codonopsis 1200-3000 part, Poria 500-1500 part, Rhizoma Dioscoreae 950-2500 part, charred Cortex Eucommiae 300-1200 part, Rhizoma Cibotii 100-1500 part, processed with wine Herba Cistanches 3000-6500 part, Semen Juglandis 900-1700 part, Herba Epimedii (processed) 900-3500 part, salt is fried Semen Astragali Complanati 900-1700 part.
6. the medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney according to claim 3, it is characterized in that comprising by weight: Radix Codonopsis 1200-3000 part, Poria 500-1500 part, Rhizoma Dioscoreae 950-2500 part, charred Cortex Eucommiae 300-1200 part, Rhizoma Cibotii 100-1500 part, processed with wine Herba Cistanches 3000-6500 part, Semen Juglandis 900-1700 part, Herba Epimedii (processed) 900-3500 part, salt is fried Semen Astragali Complanati 900-1700 part.
7. keep fit the medicine of brain-strengthening according to claim 5 or 6 described a kind of enriching yin and nourishing kidney, it is characterized in that described Radix Codonopsis is 1875 parts, described Poria is 750 parts, described Rhizoma Dioscoreae is 1500 parts, and described charred Cortex Eucommiae is 750 parts, and described Rhizoma Cibotii is 375 parts, described processed with wine Herba Cistanches is 5000 parts, described Semen Juglandis is 1250 parts, and described Herba Epimedii (processed) is 2000 parts, and it is 1250 parts that described salt is fried Semen Astragali Complanati.
8. keep fit the medicine of brain-strengthening according to claim 1 or 3 or 5 or 6 described a kind of enriching yin and nourishing kidney, it is characterized in that comprising by weight: Fructus Rubi 1000-3000 part, Fructus Lycii 500-1500 part, processed with wine Fructus Schisandrae Chinensis 300-1200 part, Semen Cuscutae 600-1700 part, processed with wine Fructus Corni 500-1800 part, Os Draconis (calcined) 250-1500 part, Radix Glycyrrhizae 100-900 part.
9. the medicine of brain-strengthening is kept fit in a kind of enriching yin and nourishing kidney according to claim 8, it is characterized in that described Fructus Rubi is 2000 parts, described Fructus Lycii is 750 parts, described processed with wine Fructus Schisandrae Chinensis is 750 parts, described Semen Cuscutae is 1250 parts, described processed with wine Fructus Corni is 750 parts, and described Os Draconis (calcined) is 625 parts, and described Radix Glycyrrhizae is 375 parts.
10. the preparation method of medicine of brain-strengthening is kept fit in enriching yin and nourishing kidney, it is characterized in that comprising the steps:
(1) takes by weighing Testis et Pentis Canis 1500-2500 part, Ligamentum cervi 20-80 part, take the lead mouth and go pawl sparrow meat 5500-9500 part, Testis Et penis Equi 750-1100 part, dried shrimps 300-900 part, Cornu Cervi Pantotrichum 500-1200 part, Hippocampus 100-1500 part, HAIQU 200-1000 part, system Os pardi 10-100 part, Gecko 100-850 part, Radix Ginseng 300-1200 part, Radix Astragali 100-1200 part, Radix Angelicae Sinensis 300-1500 part, Radix Rehmanniae Preparata 3000-6000 part, Radix Aconiti Lateralis Preparata 3500-7000 part, Cortex Cinnamomi 200-750 part, Fructus Caryophylli 1500-4500 part, processed with salt Fructus Foeniculi 950-1800 part, Radix Achyranthis Bidentatae 300-1200 part, processed with salt Fructus Psoraleae 700-1700 part, Radix Codonopsis 1200-3000 part, Poria 500-1500 part, Rhizoma Dioscoreae 950-2500 part, charred Cortex Eucommiae 300-1200 part, Rhizoma Cibotii 100-1500 part, processed with wine Herba Cistanches 3000-6500 part, Semen Juglandis 900-1700 part, Herba Epimedii (processed) 900-3500 part, salt is fried Semen Astragali Complanati 900-1700 part, Fructus Rubi 1000-3000 part, Fructus Lycii 500-1500 part, processed with wine Fructus Schisandrae Chinensis 300-1200 part, Semen Cuscutae 600-1700 part, processed with wine Fructus Corni 500-1800 part, Os Draconis (calcined) 250-1500 part, Radix Glycyrrhizae 100-900 part;
(2) described charred Cortex Eucommiae is ground into powder, it is standby to cross 120 mesh sieves;
(3) with described Radix Rehmanniae Preparata, take the lead to boil 2-3 time before mouth goes the pawl sparrow meat to add the water of 5-10 times of weight, boiled 2-5 hour at every turn, merge decocting liquid, filter the condensed cream that it is 1.1-1.5 that filtrate is condensed into 45-55 ℃ of relative density;
(4) described Testis Et penis Equi, Testis et Pentis Canis, Ligamentum cervi, dried shrimps are added 3000-5000 times of weight yellow wine and put in the container, sealing, steam exhausted by medical material to yellow wine till, take out drying, crushing screening;
(5) with all the other described 29 flavor decoction pieces crushing screenings; Add the powder that described step (4) makes, add the condensed cream that described step (3) makes, add proper honey and water, pill is rushed circle, and drying is with described Cortex Eucommiae powdered carbon coating, polishing, drying, promptly.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2006101298102A CN1973872B (en) | 2006-12-04 | 2006-12-04 | Medicine for nourishing Yin, invigorating kidney, strengthening physique and nourishing brain and its prepn |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2006101298102A CN1973872B (en) | 2006-12-04 | 2006-12-04 | Medicine for nourishing Yin, invigorating kidney, strengthening physique and nourishing brain and its prepn |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1973872A true CN1973872A (en) | 2007-06-06 |
| CN1973872B CN1973872B (en) | 2010-04-07 |
Family
ID=38124406
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2006101298102A Active CN1973872B (en) | 2006-12-04 | 2006-12-04 | Medicine for nourishing Yin, invigorating kidney, strengthening physique and nourishing brain and its prepn |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1973872B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104721640A (en) * | 2015-02-27 | 2015-06-24 | 周舜宁 | Traditional Chinese medicine composition for tonifying kidney |
| CN109432266A (en) * | 2018-12-14 | 2019-03-08 | 天津中新药业集团股份有限公司乐仁堂制药厂 | Application of the Chinese medicine in preparation anti-hypoxia medicament |
| CN109481558A (en) * | 2018-12-18 | 2019-03-19 | 天津中新药业集团股份有限公司乐仁堂制药厂 | Chinese medicine composition is preparing the application in fatigue proof drug |
| CN109820870A (en) * | 2018-12-17 | 2019-05-31 | 天津中新药业集团股份有限公司乐仁堂制药厂 | Chinese medicine composition improves the application in immune function drug in preparation |
-
2006
- 2006-12-04 CN CN2006101298102A patent/CN1973872B/en active Active
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104721640A (en) * | 2015-02-27 | 2015-06-24 | 周舜宁 | Traditional Chinese medicine composition for tonifying kidney |
| CN109432266A (en) * | 2018-12-14 | 2019-03-08 | 天津中新药业集团股份有限公司乐仁堂制药厂 | Application of the Chinese medicine in preparation anti-hypoxia medicament |
| CN109820870A (en) * | 2018-12-17 | 2019-05-31 | 天津中新药业集团股份有限公司乐仁堂制药厂 | Chinese medicine composition improves the application in immune function drug in preparation |
| CN109481558A (en) * | 2018-12-18 | 2019-03-19 | 天津中新药业集团股份有限公司乐仁堂制药厂 | Chinese medicine composition is preparing the application in fatigue proof drug |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1973872B (en) | 2010-04-07 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100337662C (en) | Medicinal composition for treating hyperlipemia and its preparing method | |
| CN1915399A (en) | Preparation for treating high blood pressure, high blood fat, obesity, and climacteric syndrome, and preparation method | |
| CN1239183C (en) | A pharmaceutical composition made from Chinese traditional medicine and preparation method thereof | |
| CN1973872A (en) | Medicine for nourishing Yin, invigorating kidney, strengthening physique and nourishing brain and its prepn | |
| CN1245189C (en) | Composition for strengthening body resistance and restoring and function, strengthening spleen and kidney, relieving metal stress and promoting blood circulation to remove blood stasis | |
| CN1493319A (en) | Medicine composition for treating neurasthenia | |
| CN1191082C (en) | Chinese medicinal composition for treating fatty liver and its preparation method | |
| CN1813819A (en) | Hedgehog hydnum fruiting body or hyphostroma and culture extract and formulation and preparing method | |
| CN100341555C (en) | Chinese traditional medicine in use for nursing body and regulating feeling and oneself | |
| CN1203872C (en) | Medicine for curing chronic colitis | |
| CN1232267C (en) | Compound plant medicine and its application | |
| CN1559495A (en) | Deer's fetus granular Chinese madicinal preparation and its production technology | |
| CN100344304C (en) | Chinese medicinal preparation for treating consumptive disease and its making method thereof | |
| CN1297290C (en) | Medicinal composition for treating coronary heart disease and stenocardia and its preparation method | |
| CN1264537C (en) | Capsule | |
| CN1314418C (en) | Medicine for clearing away lung-heat, eliminating phaegn, reliveing cough and asthma and its preparing method | |
| CN1207030C (en) | Natural bioreaction regulator with the functions of resisting cancer, resisting free radical damage and regulating immunity | |
| CN1282470C (en) | Traditional Chinese medicine for anti depression | |
| CN1582981A (en) | Chinese medicinal composite preparation against virus | |
| CN1660259A (en) | Chinese traditional medicine for treating imitable bowel syndrome and preparation method | |
| CN1233361C (en) | Traditional Chinese medicine composition for treating cardiovascular disease | |
| CN1857509A (en) | Health composition for strengthening women's immunity and its preparing method | |
| CN1872246A (en) | Capsule of Baji, and preparation method | |
| CN1201797C (en) | Medicine for treating gastritis and preparation process thereof | |
| CN1239170C (en) | Chinese patent drug for treating liver cancer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CP01 | Change in the name or title of a patent holder | ||
| CP01 | Change in the name or title of a patent holder |
Address after: 300380 Yumen Road, Xiqing District, Tianjin Patentee after: Lerentang Pharmaceutical Factory of Jinyao Darentang Group Co.,Ltd. Address before: 300380 Yumen Road, Xiqing District, Tianjin Patentee before: Letrentang pharmaceutical factory of Tianjin Zhongxin Pharmaceutical Group Co.,Ltd. |