CN1970044A

CN1970044A - Medicinal composition for treating rheumatoid arthritis and method for preparing same

Info

Publication number: CN1970044A
Application number: CNA2006100952611A
Authority: CN
Inventors: 杨凤章
Original assignee: Individual
Current assignee: Individual
Priority date: 2006-12-07
Filing date: 2006-12-07
Publication date: 2007-05-30

Abstract

Disclosed is a medicinal combination for treating rheumatoid arthritis which comprises pill preparation and decoction preparation, the raw materials of the pill preparation comprises Chinese herbs of (by weight ratio) vomic nut 90-110 parts, achyranthes and cyathula root, Chinese ephedra, batryticated silkworm, buthus martensi karsch, frankincense, myrrh, gastrodia tuber, licorice root each 10-20 parts, the raw materials of the decoction comprises Chinese herbs of (by weight ratio) aigret mouth grass 100-125 parts, wild vine 35-45 parts, achyranthes and cyathula root, levisticum each 10-25 parts.

Description

A kind of drug regimen for the treatment of rheumatoid arthritis and preparation method thereof

Technical field

The invention belongs to Chinese medicine and preparing technical field thereof, specifically, relate to a kind of drug regimen for the treatment of rheumatoid arthritis and preparation method thereof.

Background technology

Rheumatoid arthritis be a kind of be the chronic symmetry arthritis of feature with the articular synovitis, show as local red and swollen heating, pain, belong to systemic chronic autoimmune disease, be clinical common altauna disease.Traditional medicine think exopathogenic factor be affected by the cold damp and hot evil, live moist, paddle in spite of the rain, unusual weather conditions or cold and hot reason such as staggered so that pathogen invasion muscle joint, meridians and fall ill; The endogenous cause of ill natural endowment is plain loses, deficiency of both the liver and kidney, imbalance of YIN and YANG, the day after tomorrow are taken good care of oneself accidentally, deficiency of qi and blood, lose blood puerperal or work and rest excessively causes liver, kidney, Pi three deficiency of five ZANG-organs damage, and three dirty functions are closely related.When liver, kidney, Pi three deficiency of five ZANG-organs decrease, deterioration, biochemical dereliction of duty, imbalance mutually such as cause internal organs, gas, blood, seek, defend, yin or yang excess, decline partially, thus cause hypoimmunity, be the main root that forms rheumatoid arthritis.Rheumatoid arthritis is because QI and blood is lost fewly, and the stasis circumfluence is not smooth, and phlegm accumulating with stagnant blood is between bone and cause arthroncus, muscle committee contracts, stiff, lopsided, the pain journey heals than long and touching difficulty, and human physical and mental health in serious threat, is one of generally acknowledged in the world at present difficult miscellaneous diseases.

Summary of the invention

The problem to be solved in the present invention provides a kind of drug regimen for the treatment of rheumatoid arthritis, and this drug regimen is used, and to atrophic diseases cure rate height, does not recur after healing, and the invention provides the preparation method of this drug regimen simultaneously.

For this reason, the drug regimen that the present invention is used for treating rheumatoid arthritis by pill and the decoction that is used for taking pill form, wherein:

Pill is by comprising that the Chinese herbal medicine of following weight proportion by part is made: 10～20 parts of Radix Achyranthis Bidentataes, 10～20 parts in Herba Ephedrae, 10～20 parts of Bombyx Batryticatus, 10～20 parts of Scorpios, 10～20 parts of Olibanums, 10～20 parts of Myrrhas, 90～110 parts of vomiting nuts, 10～20 parts in Rhizoma Gastrodiae, 10～20 parts of Geranium carolinianum L.s, 10～20 parts in Radix Glycyrrhizae;

Decoction forms by comprising that following weight proportion boils with wine and water low baking temperature by the Chinese herbal medicine of part: 10～25 parts of Radix Achyranthis Bidentataes, 35～45 parts of Herba Anemones vitifoliaes, 10～25 parts of Radix Angelicae Pubescentiss, parasitic 10～25 parts, 100～125 parts of Geranium carolinianum L.s.

In order to obtain the described drug regimen that is used for treating rheumatoid arthritis, decoction and pill are made respectively, are used.

The manufacturing process of decoction is: be equipped with earlier good each required Chinese herbal medicine, the per 250 parts of Chinese herbal medicine after preparing of part meter add 2500 parts of Chinese liquor by weight ratio then, and 600 parts in water, low baking temperature are endured to 1250 parts of medicine juice;

The manufacturing process of pill is: vomiting nut is gone into marmite decocting in water detoxification with Semen phaseoli radiati, boil the back peeling, it is thin as a piece of paper to cut into slices, and parching to brown cools off stand-by then; Scorpio and Olibanum are put on the tile roasting, whole oil stains are gone in the tile with low baking temperature; Vomiting nut behind the independent respectively parching to brown of other all components behind the peeling detoxification and Scorpio, the Olibanum after the stain of deoiling all mix, and are ground into smalls, are made into pill again.

Radix Achyranthis Bidentatae bitter in the mouth acid in the drug component of the present invention is flat, has the effect of the diuresis of stimulating the menstrual flow, heat-clearing and toxic substances removing and promoting blood circulation and stopping pain.Herba Ephedrae acrid in the mouth, warm in nature, suffering can be dispersed, but the temperature cold relieving, the effect that has the perspiration of inducing sweat, removes the fever of the body headache and remove wind, dissipating cold.It is hot that Bombyx Batryticatus distinguishes the flavor of, and property is flat, has except that rheumatism, wind heat, and wind, puts out liver-fire and end the effect of twitching, disease such as be commonly used to treat tic of the limbs and headache due to pathogenic wind-heat, toothache, the ophthalmalgia of infantile convulsion and pain disease and have sore throat.The Scorpio acrid in the mouth, poisonous, the effect that has expelling wind and removing dampness and spasmolytic to twitch is commonly used to treat the tic of the limbs that hemiplegia and infantile convulsion pain disease cause.Olibanum acrid in the mouth hardship, warm in nature, the effect of blood circulation promoting regulates qi, pain relieving granulation promoting is arranged, chest and abdomen swelling and pain, the congestion that is commonly used to treat QI and blood retardance disease such as have a pain.The Myrrha bitter in the mouth, property is flat, is commonly used to control the skin ulcer pain relieving, controls traumatic injury, removing blood stasis ventilation etc.The vomiting nut bitter in the mouth, cold in nature, very toxic, detumescence collateral dredging effect is arranged, generally be used for treating sore throat pain infections, diseases such as paralysis muscle arteries and veins contracture numb and that cause because of rheumatism, total numbness paralysis.The Geranium carolinianum L. bitter in the mouth, the little suffering of property has the effect of expelling wind and removing dampness, is used for treating rheumatic arthralgia, numb limbs and tense tendons and articular instability etc.The Herba Anemones vitifoliae sweet in the mouth, property is flat, has inducing diuresis to remove edema, and heat clearing away is quenched one's thirst and the effect of wind-damp dispelling.The Radix Angelicae Pubescentis acrid in the mouth, warm in nature, wind-damp dispelling, analgesic effect are arranged.Parasitic bitter in the mouth, property is flat, and the effect of nourishing blood and preventing abortion, wind-damp dispelling and blood pressure lowering is arranged.The said herbal medicine organic assembling is used for boiling decoction respectively and is made into pill, also pill can be made into capsule with industrial means.Take pill with decoction during use, the wine in the decoction is gone into meridians with guiding drug.Decoction also can be taken separately, the use of decoction one day three times, because spirituosity in the decoction, each consumption should be decided according to patient's capacity for liquor, and decoction also can directly be used for the wiping affected part; Pill once a day, the adult is no more than 2 grams at every turn, physical weakness the person cut down according to the circumstance, and takes before being preferably in evening sleep, sat quietly behind the clothes 10 minutes.Because pill has certain toxicity, thus can not directly take by water, otherwise can alleviate drug effect.If the patient staring spells phenomenon occurs after taking pill, drink cold boiled water immediately and separate.

Drug regimen among the present invention is through the clinical use of last 100 routine patients, and total effective rate reaches more than 95%, and follow up a case by regular visits to after healing and do not have the recurrence sign, the cure rate height, easy to use, cost is low, is worth promoting and commercial application.

The specific embodiment

Below in conjunction with specific embodiment the present invention is described in further detail.

Embodiment 1:

Make pill, vomiting nut 100 grams are gone into marmite decocting in water detoxification with Semen phaseoli radiati, boil the back peeling, and it is thin as a piece of paper to cut into slices, and parching to brown cools off stand-by then; Scorpio, each 15 gram of Olibanum are put on the tile roasting with low baking temperature, and whole oil stains are gone in the tile; Vomiting nut behind Radix Achyranthis Bidentatae, Herba Ephedrae, Bombyx Batryticatus, Myrrha, Rhizoma Gastrodiae, Geranium carolinianum L., the independent respectively parching to brown of each 15 gram of Radix Glycyrrhizae behind the peeling detoxification and Scorpio, the Olibanum after the stain of deoiling all mix, be ground into smalls, be made into pill again, every pill is not more than 2 grams.

Make decoction, with Radix Achyranthis Bidentatae 18 grams, Herba Anemones vitifoliae 28 grams, Radix Angelicae Pubescentis 15 grams, parasitic 13 grams, Geranium carolinianum L. 100 grams, Radix Rubiae 15 grams, Mulberry jealousy 18 grams, Daphne giraldii Nitsche 15 grams, CHENMA 8 grams and Herba Girardinlae Diversifoliae root 20 grams are put into marmite together, add Chinese liquor 2500 grams, water 600 grams, low baking temperature are endured to 1250 gram medicine juice, filter medicinal residues, obtain required decoction.

Take pill with decoction during use, decoction also can be taken separately, the use of decoction limit one day three times, because spirituosity in the decoction, each consumption should be decided according to patient's capacity for liquor, and decoction also can directly be used for the wiping affected part; Pill once a day, the adult is no more than 2 grams at every turn, physical weakness the person cut down according to the circumstance, and takes before being preferably in evening sleep, sat quietly behind the clothes 10 minutes.Because pill has certain toxicity, thus can not directly take by water, otherwise can alleviate drug effect.If the patient staring spells phenomenon occurs after taking pill, drink cold boiled water immediately and separate.

Embodiment 2:

Make pill, vomiting nut 110 grams are gone into marmite decocting in water detoxification with Semen phaseoli radiati, boil the back peeling, and it is thin as a piece of paper to cut into slices, and parching to brown cools off stand-by then; Scorpio, each 18 gram of Olibanum are put on the tile roasting with low baking temperature, and whole oil stains are gone in the tile; Vomiting nut behind Radix Achyranthis Bidentatae, Herba Ephedrae, Bombyx Batryticatus, Myrrha, Rhizoma Gastrodiae, Geranium carolinianum L., the independent respectively parching to brown of each 12 gram of Radix Glycyrrhizae behind the peeling detoxification and Scorpio, the Olibanum after the stain of deoiling all mix, be ground into smalls, be made into pill again, every pill is not more than 2 grams.

Make decoction, with Radix Achyranthis Bidentatae 20 grams, Herba Anemones vitifoliae 26 grams, Radix Angelicae Pubescentis 13 grams, parasitic 15 grams, Geranium carolinianum L. 110 grams, Radix Rubiae 10 grams, Mulberry jealousy 18 grams, Daphne giraldii Nitsche 10 grams, CHENMA 10 grams and Herba Girardinlae Diversifoliae root 18 grams are put into marmite together, add Chinese liquor 2500 grams, water 600 grams, low baking temperature are endured to 1250 gram medicine juice, filter medicinal residues, obtain required decoction.

Using method is with embodiment 1.

Embodiment 3:

Make pill, vomiting nut 100 grams are gone into marmite decocting in water detoxification with Semen phaseoli radiati, boil the back peeling, and it is thin as a piece of paper to cut into slices, and parching to brown cools off stand-by then; Scorpio, each 20 gram of Olibanum are put on the tile roasting with low baking temperature, and whole oil stains are gone in the tile; Vomiting nut behind Radix Achyranthis Bidentatae, Herba Ephedrae, Bombyx Batryticatus, Myrrha, Rhizoma Gastrodiae, Geranium carolinianum L., the independent respectively parching to brown of each 15 gram of Radix Glycyrrhizae behind the peeling detoxification and Scorpio, the Olibanum after the stain of deoiling all mix, be ground into smalls, be made into pill again, every pill is not more than 2 grams.

Make decoction, with Radix Achyranthis Bidentatae 15 grams, Herba Anemones vitifoliae 23 grams, Radix Angelicae Pubescentis 15 grams, parasitic 18 grams, Geranium carolinianum L. 100 grams, Radix Rubiae 12 grams, Mulberry jealousy 16 grams, Daphne giraldii Nitsche 12 grams, CHENMA 12 grams and Herba Girardinlae Diversifoliae root 17 grams are put into marmite together, add Chinese liquor 2500 grams, water 600 grams, low baking temperature are endured to 1250 gram medicine juice, filter medicinal residues, obtain required decoction.

Using method is with embodiment 1.

Claims

1, a kind of drug regimen for the treatment of rheumatoid arthritis is characterized in that the decoction that is taken pill by pill and being used for forms, wherein:

2, a kind of drug regimen for the treatment of rheumatoid arthritis according to claim 1, it is characterized in that described decoction also adds Radix Rubiae, Mulberry jealousy, Daphne giraldii Nitsche, CHENMA and Herba Girardinlae Diversifoliae root are arranged before boiling, its weight proportion by per 100～125 parts Geranium carolinianum L. of part to 10～20 parts of Radix Rubiae, 15～25 parts of Mulberry jealousys, 10～20 parts of Daphne giraldii Nitsche, 5～10 parts of CHENMA, 15～25 parts of Herba Girardinlae Diversifoliae roots should be arranged.

3, according to the described a kind of drug regimen for the treatment of rheumatoid arthritis of claim 2, the weight proportion that it is characterized in that described decoction each Chinese herbal medicine, Chinese liquor and water before boiling is counted by part: 20 parts of Radix Achyranthis Bidentataes, 30 parts of Herba Anemones vitifoliaes, 15 parts of Radix Angelicae Pubescentiss, parasitic 20 parts, 105 parts of Geranium carolinianum L.s, 15 parts of Radix Rubiae, 20 parts of Mulberry jealousys, 15 parts of Daphne giraldii Nitsche, 7 parts of CHENMA, 20 parts of Herba Girardinlae Diversifoliae roots, 2500 parts of Chinese liquor, 1250 parts in water;

The weight proportion of each Chinese herbal medicine is counted by part in the described pill: 15 parts of Radix Achyranthis Bidentataes, 15 parts in Herba Ephedrae, 15 parts of Bombyx Batryticatus, 15 parts of Scorpios, 15 parts of Olibanums, 15 parts of Myrrhas, 100 parts of vomiting nuts, 15 parts in Rhizoma Gastrodiae, 15 parts of Geranium carolinianum L.s, 15 parts in Radix Glycyrrhizae.

4, a kind of preparation method as treatment medicine for treating rheumatoid arthritis combination as described in the claim 3, the manufacturing process that it is characterized in that described decoction is: be equipped with good each required Chinese herbal medicine earlier, by weight ratio part the per 250 parts of Chinese herbal medicine after preparing of meter add 2500 parts of Chinese liquor then, 600 parts in water, low baking temperature are endured to 1250 parts of medicine juice;

The manufacturing process of described pill is: vomiting nut is gone into marmite decocting in water detoxification with Semen phaseoli radiati, boil the back peeling, it is thin as a piece of paper to cut into slices, and parching to brown cools off stand-by then; Scorpio and Olibanum are put on the tile roasting, whole oil stains are gone in the tile with low baking temperature; Vomiting nut behind the independent respectively parching to brown of other all components behind the peeling detoxification and Scorpio, the Olibanum after the stain of deoiling all mix, and are ground into smalls, are made into pill again.