CN1939257A - Pure natural plant additive of sunproofing cosmetics - Google Patents

Abstract

A natural vegetative additive of the cosmetic for shielding sunlight and protecting skin is prepared from 11 Chinese-medicinal materials including sophora flower, wild jujube, aloe, liquorice root, etc through extracting in alcohol. Its extracting process is also disclosed.

Description

A kind of pure natural plant additive of sun-proof cosmetic skin care product

Technical field

The present invention relates to sun care preparations, specifically the sun-proof function combinations thing of sun care preparations.

Background technology

Functional cosmetic skin care product have been continued to use for many years, and sun-proof cosmetic skin care product wherein appear on the market in a large number with the needs of tourism development, this be because the people under burning sun, or during seawater bath, skin is often burnt by the sunlight direct projection, produces erythema, twinge, and heavy then decortication is bubbled.The light of infringement skin mainly is the ultraviolet of wavelength 290-390nm in the sunlight, so the sun-proof finger that is to say prevents the ultraviolet infringement of this wavelength.Its sun-proof functional component of present sun care preparations roughly has two big classes, and a class is the physical sunscreen composition, and another kind of is chemical sun-prevention component.Physical sunscreen composition functional component has zinc oxide, ferrum oxide, titanium dioxide etc.Its objective is block, reflected sunlight, but because the solution of the infiltration blending of the interface of these inorganic matter microgranules and other compositions of cosmetics is undesirable all the time, microgranule requires high degree of dispersion in cosmetics in addition, but in fact also cannot say for sure to demonstrate,prove the dispersibility in later stage, so can cause storage period microgranule sinking, cohesion, cause product stability poor, also useful additive method is transformed the microgranule interface, be intended to try to achieve the stability in cosmetics, but the generation that things turn out contrary to one's wishes has also been arranged gelatin phenomenon.Because there are above these problems in the physical sunscreen functional additive, unstable product quality not only, and influenced sun-proof poor performance.The sun-proof functional additive of chemistry is the composition that existing market sun-proof skin care cosmetics generally adopt; this is because chemical sun-proof functional component absorbs harmful light in the sunlight; reach the purpose that protection skin is not burnt; chemical sun-prevention component material is easily produced simultaneously; be easy to cosmetics and merge mutually, and steady quality, the material of sun-proof functional component have now found that and use a lot; such as the derivant of the benzotriazole of using among the CN1425366, the dibenzoyl methane derivant.The tartaric acid dialkyl that uses among the CN1222343, pyrrolotriazine derivatives, the dibenzoyl methane that uses among the CN1274577, Methoxycinnamate.Because chemical substance itself more or less, obvious or concealed formula the people is known from experience of accumulating causes damage, and particularly finding has more irritated medical history to human body, so safety is poor.The shortcoming that exists owing to above two big classes, there is human desires to go development again from new direction, promptly be to find out a kind of new sunscreen, join steady quality in the sun care preparations, can resist the infringement of sunlight on the sun-proof result, and human body is had no side effect, as HK1031081 " a kind of sunscreen and contain as described in the cosmetics of sunscreen " skin, it is to be sun-proof functional additive with plant Stigma Croci extracting solution, and its superior part is arranged.But the croceous main place of production has only a small amount of cultivation in states such as Greece, Spain, Iran in China, and output is extremely low, and the time and effort consuming of gathering is classified rare rare medicinal herbs as in China, that is to say mainly do medicinal.Therefore the sun-proof functional additive of developing new plant becomes the needs in cosmetics market.

Summary of the invention

The plant additive that the purpose of this invention is to provide a kind of sun-proof cosmetic skin care product, it is a raw material with the natural plants, better absorption ultraviolet is arranged and repair the sunburn skin function, the steady quality of terminal cosmetic skin care product, human body is had no side effect, and raw material is easy to get, is easy to produce and store.

Technical solution of the present invention is that this plant additive is the ethanol extract of the solid constituent of following material:

A, vegetable solid composition:

Flos Sophorae 10-18 part

Semen Ziziphi Spinosae 5-13 part

Radix Polygalae 2-7 part

Aloe 10-18 part

Fructus Myricae rubrae 7-12 part

Rhizoma Phragmitis 8-13 part

Flos Matricariae chamomillae 5-9 part

Fructus rhamni (Rhamnus davurica Pall.) 9-14 part

Cortex Fraxini 3-7 part

Herba Menthae 1-5 part

Radix Glycyrrhizae 2-7 part

B, ethanol part:

With A vegetable solid composition gross weight is that 1,70% ethanol is vegetable solid composition gross weight 3-7 times;

C, get A vegetable solid component substances, after cleaning, pulverize, add 70% ethanol, put into the multimode preparing system of microwave sample, controlled pressure heats 60S at 0.1-0.3Mpa, and concentrating under reduced pressure 1 hour is got supernatant and is indication plant additive of the present invention.

The additive of pure natural plant preferably of a kind of sun-proof cosmetic skin care product of the present invention is ethanol extracts of the solid constituent of following material:

A, vegetable solid composition:

Flos Sophorae 10-16 part

Semen Ziziphi Spinosae 5-12 part

Radix Polygalae 2-6 part

Aloe 10-18 part

Fructus Myricae rubrae 7-11 part

Rhizoma Phragmitis 8-12 part

Flos Matricariae chamomillae 5-8 part

Fructus rhamni (Rhamnus davurica Pall.) 9-13 part

Cortex Fraxini 3-6 part

Herba Menthae 1-4 part

Radix Glycyrrhizae 2-6 part

B, ethanol part:

With vegetable solid composition gross weight is that 1,70% alcohol is solid constituent gross weight 4-6 times,

C, get A vegetable solid component substances, after cleaning, pulverize, add 70% ethanol, put into the multimode preparing system of microwave sample, controlled pressure heats 60S at 0.15-0.25Mpa, and concentrating under reduced pressure 1 hour is got supernatant and is indication plant additive of the present invention.

The pure natural plant additive of the best of a kind of sun-proof cosmetic skin care product of the present invention is the ethanol extract of the solid constituent of following material:

A, vegetable solid composition:

15 parts in Flos Sophorae

10 parts of Semen Ziziphi Spinosaes

5 parts of Radix Polygalaes

17 parts of Aloes

10 parts in Fructus Myricae rubrae

11 parts of Rhizoma Phragmitiss

7 parts of Flos Matricariae chamomillaes

12 parts of Fructus rhamni (Rhamnus davurica Pall.)s

5 parts of Cortex Fraxinis

3 parts of Herba Menthaes

5 parts in Radix Glycyrrhizae

B, ethanol part:

With vegetable solid composition gross weight is that 1,70% ethanol is 5 times of solid constituent gross weights;

C, get A vegetable solid component substances, after cleaning, pulverize, add 70% ethanol, put into the multimode preparing system of microwave sample, controlled pressure heats 60S at 0.2Mpa, and concentrating under reduced pressure 1 hour is got supernatant and is indication plant additive of the present invention.

The characteristic functions of each component substances composition of the present invention is:

The Radix Polygalae Main Ingredients and Appearance is a saponin, absorbs ultraviolet between ripple 310-315nm.

Aloe contains multiple barbaloin, can prevent ultraviolet, and can the calm skin of repairing sunburn.

Fructus Myricae rubrae contains myricetin, can both absorb ultraviolet in the very wide scope of wavelength.

Rhizoma Phragmitis contains Coixol, vitamin C etc., and good anti-sunlight function is also arranged.

Flos Matricariae chamomillae contains flavonoid compositions such as globulariacitrin, can absorb ultraviolet.

Fructus rhamni (Rhamnus davurica Pall.) contains emodin, chrysophanol etc., can prevent dermatitis solaris, medicine Exposure to Sunlight disease and X ray, ultraviolet harmful irradiation.

Cortex Fraxini contains esculiw, but the strong absorption ultraviolet.

Herba Menthae is used for skin refrigerant comfort.

Radix Glycyrrhizae has Detoxication, and the title of separating hundred poison is arranged, and can neutralize or remove or reduce the noxious substance of cosmetics.

Manufacture method of the present invention is to get each vegetable solid component substances, after cleaning, pulverizes, and adds 70% alcohol of 3 to 7 times of amounts, put into the multimode preparing system of microwave sample, controlled pressure heats 60S at 0.1-0.3Mpa, concentrating under reduced pressure 1 hour is got supernatant, is plant additive of the present invention.Above manufacture method is to utilize the MPS-100D multimode preparing system of microwave sample of effective high pressure control accuracy, by orthogonal experiment design method, the optimum condition of microwave extraction comprehensively screened draws.Wherein the optimised quantity of alcohol solvent is 5 times.

Each plant component of the present invention is all generally planted in China, and it is many to produce the seedbed, and output is abundant, is easy to buy and inexpensive.

Advantage of the present invention is to be raw material with the natural plants, better absorption ultraviolet is arranged and repair the sunburn skin function, and the steady quality of terminal cosmetic skin care product has no side effect to human body, and raw material is easy to get, and is easy to produce and store.

The specific embodiment

Embodiment one

Plant additive of the present invention is the ethanol extract of the solid constituent of following material:

A, vegetable solid composition:

15 parts in Flos Sophorae

10 parts of Semen Ziziphi Spinosaes

5 parts of Radix Polygalaes

17 parts of Aloes

10 parts in Fructus Myricae rubrae

11 parts of Rhizoma Phragmitiss

7 parts of Flos Matricariae chamomillaes

12 parts of Fructus rhamni (Rhamnus davurica Pall.)s

5 parts of Cortex Fraxinis

3 parts of Herba Menthaes

5 parts in Radix Glycyrrhizae

B, ethanol part

With A vegetable solid composition gross weight is that 1,70% ethanol is 5 times of vegetable solid composition gross weights;

C, get A vegetable solid component substances, after cleaning, pulverize, add 70% alcohol, put into the multimode preparing system of microwave sample, controlled pressure heats 60S at 0.2Mpa, and concentrating under reduced pressure 1 hour is got supernatant and is indication plant additive of the present invention.

Embodiment two

Plant additive of the present invention is the ethanol extract of the solid constituent of following material:

A, vegetable solid composition:

18 parts in Flos Sophorae

5 parts of Semen Ziziphi Spinosaes

2 parts of Radix Polygalaes

18 parts of Aloes

7 parts in Fructus Myricae rubrae

8 parts of Rhizoma Phragmitiss

5 parts of Flos Matricariae chamomillaes

14 parts of Fructus rhamni (Rhamnus davurica Pall.)s

3 parts of Cortex Fraxinis

1 part of Herba Menthae

2 parts in Radix Glycyrrhizae

B, ethanol part

With A vegetable solid composition gross weight is that 1,70% alcohol is 7 times of vegetable solid composition gross weights;

C, get A vegetable solid component substances, after cleaning, pulverize, add 70% alcohol, put into the multimode preparing system of microwave sample, controlled pressure heats 60S at 0.3Mpa, and concentrating under reduced pressure 1 hour is got supernatant and is indication plant additive of the present invention.

Embodiment three

Plant additive of the present invention is the ethanol extract of the solid constituent of following material:

A vegetable solid composition:

10 parts in Flos Sophorae

13 parts of Semen Ziziphi Spinosaes

7 parts of Radix Polygalaes

10 parts of Aloes

11 parts in Fructus Myricae rubrae

13 parts of Rhizoma Phragmitiss

9 parts of Flos Matricariae chamomillaes

9 parts of Fructus rhamni (Rhamnus davurica Pall.)s

7 parts of Cortex Fraxinis

5 parts of Herba Menthaes

7 parts in Radix Glycyrrhizae

B, ethanol part

With A vegetable solid composition gross weight is that 1,70% ethanol is 3 times of vegetable solid composition gross weights;

C, get A vegetable solid component substances, after cleaning, pulverize, add 70% ethanol, put into the multimode preparing system of microwave sample, controlled pressure heats 60S at 0.1Mpa, and concentrating under reduced pressure 1 hour is got supernatant and is indication plant additive of the present invention.

The present invention gets above-mentioned plant extraction liquid and is mixed with sunscreen, and it is as follows to fill a prescription:

A phase: deionized water 72.5%

Propylene glycol 3%

HANSHENGJIAO 0.3%

B phase: white oil 5%

Isopropyl palmitate 3%

Tween-60 2%

This dish-60 1.8%

Hexadeca-octadecyl alcohol 1.5%

Monoglyceride 1.3%

Silicone oil 1%

Methyl hydroxybenzoate 0.2%

Propylparaben 0.1%

C phase: plant extraction liquid 8%

D phase: essence 0.3%

With A heat phase to 80 degree, be incubated 20 minutes; With the dissolving of B heat phase to 80 degree evenly; With A phase suction vacuum emulsifying pot, again with the suction of B phase, stirred 3 minutes, opened homogenizing 5 minutes, be cooled to 40 degree and add C phase, D phase, discharging stirs.

Product is tested by " sun care preparations sun protection coefficient (spf value) body measurements method " in China's Ministry of Public Health " cosmetics health standard " (version in 2002).

In following table, " standard substance " are by " standard substance " of regulation in China's Ministry of Public Health " sun care preparations sun protection coefficient (spf value) human test method ", testing sample one, two, three is respectively the plant extraction liquid of embodiment one, two, three, all join respectively in the above sunscreen prescription, promptly obtain testing sample one, two, three with 8% amount.

Embodiment 1

Select the experimenter: totally 10 people, male 1 people, women 9 people, 31.8 ± 7.9 years old mean age, meet the experimenter and volunteer inclusion criteria age 19-45 year.

Standard reference material and sample spf value measurement result

Experimenter's numbering	Sex	Age	The standard substance spf value	Testing sample one spf value
					01	The woman	30	4	23.24
02	The woman	37	4	16.51
					03	The woman	19	4	18.86
04	The woman	45	4	17.45
					05	The woman	33	4	18.59
06	The man	20	5	21.25

07	The woman	37	4	23.24
					08	The woman	32	3.2	18.59
09	The woman	36	4	16.51
					10	The woman	29	4	16.99
Meansigma methods		31.8	4.02	19.12
					Standard deviation		7.9	0.43	2.58
Standard error			0.14	0.82

Conclusion: human test result shows that the spf value of institute's sample product is 19.12.

Embodiment 2

Select the experimenter: totally 10 people, male 1 people, women 9 people, 35.7 ± 4.3 years old mean age, meet the experimenter and volunteer inclusion criteria age 31-43 year.

Standard reference material and sample spf value measurement result

Experimenter's numbering	Sex	Age	The standard substance spf value	Testing sample two spf values
					01	The woman	31	4	13.96
02	The woman	43	4	17.45
					03	The woman	33	4	17.20
04	The woman	37	4	15.72
					05	The woman	32	4	17.45
06	The woman	34	4	17.71
					07	The woman	42	4	13.96
08	The man	32	3.2	17.45
					09	The woman	39	4	19.65
10	The woman	34	4	19.37
					Meansigma methods		35.7	3.92	16.99
Standard deviation		4.3	0.25	1.94

Standard error

0.08

0.61

Conclusion: human test result shows that the spf value of institute's sample product is 16.99.

Embodiment 3

Select the experimenter: totally 10 people, male 1 people, women 9 people, 33.6 ± 5.54 years old mean age, meet the experimenter and volunteer inclusion criteria age 21-40 year.

Standard reference material and sample spf value measurement result

Experimenter's numbering	Sex	Age	The standard substance spf value	Testing sample Three S's PF value
					01	The woman	21	4	12.34
02	The woman	40	3.4	15.45
					03	The woman	33	4	16.12
04	The woman	35	4	15.75
					05	The woman	31	4	14.45
06	The woman	37	4	16.01
					07	The woman	40	4	13.56
08	The man	30	3.2	14.45
					09	The woman	35	4	15.65
10	The woman	34	4	13.77
					Meansigma methods		33.6	3.86	14.75
Standard deviation		5.54	0.28	1.25
					Standard error			0.09	0.39

Conclusion: human test result shows that the spf value of institute's sample product is 14.75.

Product is carried out repeatedly the skin irritation test, press skin irritation/corrosion test method in the Ministry of Public Health " cosmetics health standard " (version in 2002).

In the following tabulation, " reference substance " is the reference substance of defined in the skin irritation corrosion testing method in the cosmetics health standard, and sample is the testing sample one, two, three described in above SPF measures.

Smear number of times	Number of animals (only)	The irritant reaction integration
								Sample (being testing sample one)			Reference substance
		Erythema	Edema	Total points	Erythema	Edema	Total points
								1	4	0	0	0	0	0	0
2	4	1	0	1	0	0	0
								3	4	2	0	2	0	0	0
4	4	1	0	1	0	0	0
								5	4	1	0	1	0	0	0
6	4	2	0	2	0	0	0
								7	4	3	0	3	0	0	0
8	4	2	0	2	0	0	0
								9	4	1	0	1	0	0	0
10	4	1	0	1	0	0	0
								11	4	0	0	0	0	0	0
12	4	0	0	0	0	0	0
								13	4	0	0	0	0	0	0
14	4	0	0	0	0	0	0
								14 days every animal integral means: 3.50
Every day every animal integral mean value 0.25
								Conclusion: this sunscreen to rabbit repeatedly skin irritation be nonirritant

Embodiment 2 results

Smear number of times	Number of animals (only)	The irritant reaction integration
								Sample (being testing sample two)			Reference substance
		Erythema	Edema	Total points	Erythema	Edema	Total points
								1	4	0	0	0	0	0	0

2	4	1	0	1	0	0	0
								3	4	2	0	2	0	0	0
4	4	2	0	2	0	0	0
								5	4	2	0	2	0	0	0
6	4	2	0	2	0	0	0
								7	4	2	0	2	0	0	0
8	4	2	0	2	0	0	0
								9	4	1	0	1	0	0	0
10	4	1	0	1	0	0	0
								11	4	0	0	0	0	0	0
12	4	0	0	0	0	0	0
								13	4	0	0	0	0	0	0
14	4	0	0	0	0	0	0
								14 days every animal integral means: 3.75
Every day every animal integral mean value 0.27
								Conclusion: this sunscreen to rabbit repeatedly skin irritation be nonirritant

Embodiment 3 results

Smear number of times	Number of animals (only)	The irritant reaction integration
								Sample (being testing sample three)			Reference substance
		Erythema	Edema	Total points	Erythema	Edema	Total points
								1	4	0	0	0	0	0	0
2	4	1	0	1	0	0	0
								3	4	2	0	2	0	0	0
4	4	1	0	1	0	0	0
								5	4	1	0	1	0	0	0

6	4	2	0	2	0	0	0
								7	4	3	0	3	0	0	0
8	4	2	0	2	0	0	0
								9	4	1	0	1	0	0	0
10	4	1	0	1	0	0	0
								11	4	0	0	0	0	0	0
12	4	0	0	0	0	0	0
								13	4	0	0	0	0	0	0
14	4	0	0	0	0	0	0
								14 days every animal integral means: 3.50
Every day every animal integral mean value 0.25
								Conclusion: this sunscreen to rabbit repeatedly skin irritation be nonirritant

The result proves that the sunscreen of making of this plant additive is non-stimulated to skin.

Claims (3)

1, a kind of pure natural plant additive of sun-proof cosmetic skin care product is characterized in that this plant additive is the ethanol extract of the solid constituent of following material:

A, vegetable solid composition:

Flos Sophorae 10-18 part

Semen Ziziphi Spinosae 5-13 part

Radix Polygalae 2-7 part

Aloe 10-18 part

Fructus Myricae rubrae 7-11 part

Rhizoma Phragmitis 8-13 part

Flos Matricariae chamomillae 5-9 part

Fructus rhamni (Rhamnus davurica Pall.) 9-14 part

Cortex Fraxini 3-7 part

Herba Menthae 1-5 part

Radix Glycyrrhizae 2-7 part

B, ethanol part:

With A vegetable solid composition gross weight is that 1,70% ethanol is vegetable solid composition gross weight 3-7 times,

C, get A vegetable solid component substances, after cleaning, pulverize, add 70% ethanol, put into the multimode preparing system of microwave sample, controlled pressure heats 60S at 0.1-0.3Mpa, and concentrating under reduced pressure 1 hour is got supernatant and is indication plant additive of the present invention.

2,, it is characterized in that this plant additive is the ethanol extract of the solid constituent of following material according to a kind of pure natural plant additive of sun-proof cosmetic skin care product:

A, vegetable solid composition:

Flos Sophorae 10-16 part

Semen Ziziphi Spinosae 5-12 part

Radix Polygalae 2-6 part

Aloe 10-18 part

Fructus Myricae rubrae 7-11 part

Rhizoma Phragmitis 8-12 part

Flos Matricariae chamomillae 5-8 part

Fructus rhamni (Rhamnus davurica Pall.) 9-13 part

Cortex Fraxini 3-6 part

Herba Menthae 1-4 part

Radix Glycyrrhizae 2-6 part

B, ethanol part:

With vegetable solid composition gross weight is that 1,70% alcohol is solid constituent gross weight 4-6 times,

C, get A vegetable solid component substances, after cleaning, pulverize, add 70% alcohol, put into the multimode preparing system of microwave sample, controlled pressure heats 60S at 0.15-0.25Mpa, and concentrating under reduced pressure 1 hour is got supernatant and is indication plant additive of the present invention.

3, the pure natural plant additive of a kind of sun-proof cosmetic skin care product according to claim 2 is characterized in that this plant additive is the ethanol extract of the solid constituent of following material:

A, vegetable solid composition:

15 parts in Flos Sophorae

10 parts of Semen Ziziphi Spinosaes

5 parts of Radix Polygalaes

17 parts of Aloes

10 parts in Fructus Myricae rubrae

11 parts of Rhizoma Phragmitiss

7 parts of Flos Matricariae chamomillaes

12 parts of Fructus rhamni (Rhamnus davurica Pall.)s

5 parts of Cortex Fraxinis

3 parts of Herba Menthaes

5 parts in Radix Glycyrrhizae

B, ethanol part:

With vegetable solid composition gross weight is that 1,70% ethanol is 5 times of solid constituent gross weights;

C, get A vegetable solid component substances, after cleaning, pulverize, add 70% ethanol, put into the multimode preparing system of microwave sample, controlled pressure heats 60S at 0.2Mpa, and concentrating under reduced pressure 1 hour is got supernatant and is indication plant additive of the present invention.