CN1925848A - 具有黑色素生物合成抑制活性的土曲霉酮化合物及其制备方法 - Google Patents

具有黑色素生物合成抑制活性的土曲霉酮化合物及其制备方法 Download PDF

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Publication number
CN1925848A
CN1925848A CNA2004800369129A CN200480036912A CN1925848A CN 1925848 A CN1925848 A CN 1925848A CN A2004800369129 A CNA2004800369129 A CN A2004800369129A CN 200480036912 A CN200480036912 A CN 200480036912A CN 1925848 A CN1925848 A CN 1925848A
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CN
China
Prior art keywords
terrein
melanin biosynthesis
chemical compound
compound
biosynthesis inhibitor
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Pending
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CNA2004800369129A
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English (en)
Chinese (zh)
Inventor
俞益东
金元坤
柳仁子
金钟平
李相龟
朴曙亨
金东锡
朴景赞
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Korea Research Institute of Bioscience and Biotechnology KRIBB
WELSKIN CO Ltd
Original Assignee
Korea Research Institute of Bioscience and Biotechnology KRIBB
WELSKIN CO Ltd
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Publication date
Application filed by Korea Research Institute of Bioscience and Biotechnology KRIBB, WELSKIN CO Ltd filed Critical Korea Research Institute of Bioscience and Biotechnology KRIBB
Publication of CN1925848A publication Critical patent/CN1925848A/zh
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/24—Preparation of oxygen-containing organic compounds containing a carbonyl group
    • C12P7/26—Ketones
    • C12P7/38—Cyclopentanone- or cyclopentadione-containing products
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
    • C12R2001/80—Penicillium

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Emergency Medicine (AREA)
  • Birds (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CNA2004800369129A 2003-12-12 2004-10-19 具有黑色素生物合成抑制活性的土曲霉酮化合物及其制备方法 Pending CN1925848A (zh)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020030090611A KR100586814B1 (ko) 2003-12-12 2003-12-12 멜라닌 생합성 저해 활성을 갖는 테레인 화합물 및 그의제조방법
KR1020030090611 2003-12-12

Publications (1)

Publication Number Publication Date
CN1925848A true CN1925848A (zh) 2007-03-07

Family

ID=36676122

Family Applications (1)

Application Number Title Priority Date Filing Date
CNA2004800369129A Pending CN1925848A (zh) 2003-12-12 2004-10-19 具有黑色素生物合成抑制活性的土曲霉酮化合物及其制备方法

Country Status (6)

Country Link
US (1) US20070128136A1 (ko)
EP (1) EP1691796A4 (ko)
JP (1) JP2007513941A (ko)
KR (1) KR100586814B1 (ko)
CN (1) CN1925848A (ko)
WO (1) WO2005055995A1 (ko)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100582235C (zh) * 2007-04-29 2010-01-20 厦门大学 克列维醇在制备酪氨酸酶抑制剂的应用
CN103497975A (zh) * 2013-07-02 2014-01-08 上海交通大学 伏立诺他的用途及促进海绵共生土曲霉合成(+)-Terrein的方法
CN103497976A (zh) * 2013-07-02 2014-01-08 上海交通大学 用于海绵共附生土曲霉发酵生产(+)-Terrein的人工海水及培养基
CN104893986A (zh) * 2015-05-21 2015-09-09 浙江师范大学 蜻蜓肠道菌土曲霉qt122及其代谢产物和应用
CN107281171A (zh) * 2017-06-27 2017-10-24 中国科学院上海有机化学研究所 芳香环类药物在抑制恶性黑色素瘤关键转录因子方面的应用
CN107567329A (zh) * 2015-03-05 2018-01-09 路博润先进材料公司 皮壳正青霉的发酵提取物和其美容用途

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100771523B1 (ko) 2006-04-06 2007-10-30 한국생명공학연구원 테레인을 포함하는 피부 각질 형성세포 증식 억제제
KR100872821B1 (ko) * 2007-08-08 2008-12-09 인하대학교 산학협력단 Ｍｉｔｆ 저해제 및 이를 포함하는 미백용 화장료 조성물
EP2090285A1 (en) 2008-02-18 2009-08-19 B.R.A.I.N. Biotechnology Research and Information Network AG Means and methods for controlling commensales
KR101069907B1 (ko) * 2008-09-04 2011-10-05 재단법인 제주테크노파크 비목나무 유래 추출물, 분획물 또는 화합물을 함유하는 피부 미백용 조성물
CN113846126B (zh) * 2021-10-15 2023-08-04 中国热带农业科学院热带生物技术研究所 一种抗香蕉枯萎病小分子化合物的制备方法及其应用
CN113913315B (zh) * 2021-12-01 2024-01-30 广州暨创生物医药研究院有限公司 一种具有美白祛斑功效的酵母及其应用
CN115281191B (zh) * 2022-07-26 2023-04-25 中国科学院新疆生态与地理研究所 土曲霉酮在农作物抗旱促生中的应用及其处理方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002241269A (ja) * 2001-02-16 2002-08-28 Kaken Pharmaceut Co Ltd テレインを含有する脂肪細胞分化抑制剤

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100582235C (zh) * 2007-04-29 2010-01-20 厦门大学 克列维醇在制备酪氨酸酶抑制剂的应用
CN103497975A (zh) * 2013-07-02 2014-01-08 上海交通大学 伏立诺他的用途及促进海绵共生土曲霉合成(+)-Terrein的方法
CN103497976A (zh) * 2013-07-02 2014-01-08 上海交通大学 用于海绵共附生土曲霉发酵生产(+)-Terrein的人工海水及培养基
CN103497976B (zh) * 2013-07-02 2015-08-19 上海交通大学 用于海绵共附生土曲霉发酵生产(+)-Terrein的人工海水及培养基
CN107567329A (zh) * 2015-03-05 2018-01-09 路博润先进材料公司 皮壳正青霉的发酵提取物和其美容用途
CN107567329B (zh) * 2015-03-05 2022-04-26 路博润先进材料公司 皮壳正青霉的发酵提取物和其美容用途
CN104893986A (zh) * 2015-05-21 2015-09-09 浙江师范大学 蜻蜓肠道菌土曲霉qt122及其代谢产物和应用
CN104893986B (zh) * 2015-05-21 2018-04-27 浙江师范大学 蜻蜓肠道菌土曲霉qt122及其代谢产物和应用
CN107281171A (zh) * 2017-06-27 2017-10-24 中国科学院上海有机化学研究所 芳香环类药物在抑制恶性黑色素瘤关键转录因子方面的应用

Also Published As

Publication number Publication date
KR100586814B1 (ko) 2006-06-08
EP1691796A4 (en) 2006-11-08
WO2005055995A1 (en) 2005-06-23
EP1691796A1 (en) 2006-08-23
KR20050058664A (ko) 2005-06-17
JP2007513941A (ja) 2007-05-31
US20070128136A1 (en) 2007-06-07

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CI01 Correction of invention patent gazette

Correction item: Applicant address

Correct: South Korea field wide area

False: Daejeon

Number: 10

Page: 682

Volume: 23

CI02 Correction of invention patent application

Correction item: Applicant address

Correct: South Korea field wide area

False: Daejeon

Number: 10

Page: The title page

Volume: 23

COR Change of bibliographic data

Free format text: CORRECT: APPLICANT ADDRESS; FROM: GUANGYU CITY, DATIAN COUNTY, HAN TO: GUANGYU CITY, DATIAN,KOREA

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C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication