CN1900680A - Sensing device for micro quanlity split injector - Google Patents
Sensing device for micro quanlity split injector Download PDFInfo
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- CN1900680A CN1900680A CN 200510084329 CN200510084329A CN1900680A CN 1900680 A CN1900680 A CN 1900680A CN 200510084329 CN200510084329 CN 200510084329 CN 200510084329 A CN200510084329 A CN 200510084329A CN 1900680 A CN1900680 A CN 1900680A
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- sensing apparatus
- dispenser
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- piston piece
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Abstract
The sensing device contains a micro distributed injector. The micro distributed injector includes following part: a body, operator part, and tube body with an operation space; a sensing unit setup at proper position of operation space inside tube body. The sensing device includes a micro electromechanic flow sensor. The micro electromechanic flow sensor can sense motion of air inside operation space. The micro distributed injector reaches function of fetching liquid more accurately. Further, integral measurement and analytic result are more accurate.
Description
Technical field
The invention relates to a kind of micro-dispenser, know clearly it, but refer to that especially a kind of sensed flow changes, and can further sensitive information be carried out the feedback correction, to obtain the more accurate micro-dispenser sensing apparatus that moves liquid measure.
Background technology
Generally carry out medical science, biochemical experiment or various detection, when analyzing, often utilize micro-dispenser (PIPETTE) to draw and get liquid sample, because when carrying out the test of this type of medical science, biochemistry, the value of each seed ginseng liquid must be very accurate, when the especially check of complex process, test (as the DNA detection analysis) being engaged in than precision, if the single stage to get value not accurate, often make final result produce huge deviation, or have a strong impact on the correctness of analysiss, detection.
Existing manual operation can be divided into and electronics is operated automatically in order to the micro-dispenser (PIPETTE) that draws or move liquid, and just move the liquid sampling mode and also can be divided into multitube and single hose, multitube trace dispenser 91 as shown in Figure 1 and single hose trace dispenser 92 shown in Figure 2, though aforementioned existing micro-dispenser can reach the purpose of micropipette, but it still has disappearance in the accurate control of micropipette, as shown in Figure 3, one micro-dispenser 93 is to be arranged with a pipetting sleeve pipe (pipette tip) 95 in the bottom of its body 94, the bottom of this pipetting sleeve pipe 95 is to be provided with a port 951, when piston piece 96 in this body 94 during start (as promoted by step motor), can be by liquid drawing being sucked in this pipetting sleeve pipe 95, so, because this pipetting sleeve pipe 95 needs getting the liquid sample and consider it in light of actual conditions and get liquid measure (as 20L-200L) and change at different orders, therefore, the tight ness rating of the fine variation in gap that these body 94 bottoms and the 95 long-term socket frictions of pipetting sleeve pipe are produced and pipetting sleeve pipe 95 and body 94 sockets, therefore airtight problem or other mechanical actuation gap and produce the variation of getting liquid measure and volume, this micro-volume difference is moves liquid error (pipetting error), and this error amount will influence medical science or biochemistry detection, the correctness of test or misleading analysis result.Therefore, how to make micro-dispenser can more accurate control its get the liquid measure value, really be the important directions that industry more should be researched and developed, break through.
Do not attain the desirable fact in view of micro-dispenser on its shortcoming used and the structural design thereof, this case inventor promptly sets about its solution of research and development design, hope can be developed a kind of micro-dispenser sensing apparatus that has more accuracy to promote the development of this industry, and satisfying through for a long time design has generation of the present invention.
Summary of the invention
The object of the present invention is to provide a kind of micro-dispenser sensing apparatus, it can make the liquid of getting of micro-dispenser reach effect more accurately, so make whole measure, analysis result is more accurate.
A further object of the present invention is to provide a kind of micro-dispenser sensing apparatus, and it can make the liquid status information of getting of micro-dispenser give sensing, and is able to by reached the accurate control of enthusiasm by the information feedback operation.
The present invention is that to reach the technological means that above-mentioned purpose adopts be to include a micro-dispenser, and this trace dispenser is to include a body portion, operating portion and body, and this body is to have an operating space; One sensing apparatus, this sensing apparatus are the appropriate locations of being located at this operating space in this body, and this sensing apparatus is to include a micro electronmechanical flow sensor, move but this micro electronmechanical flow sensor is a air in this operating space of sensing.
For making purpose of the present invention, technical characterictic and other effect that further understanding be arranged, cooperate now to be illustrated as follows:
Description of drawings
Fig. 1 is existing multitube trace dispenser synoptic diagram;
Fig. 2 is existing single hose trace dispenser synoptic diagram;
Fig. 3 is existing micro-dispenser body partial schematic sectional view;
Fig. 4 is the present invention's trace dispenser synoptic diagram;
Fig. 5 is the body partial schematic sectional view of piston piece propradation of the present invention;
Fig. 6 is the body partial schematic sectional view of piston piece decline state of the present invention;
Fig. 7 is a body cross-sectional schematic of the present invention;
Fig. 8 is the cross-sectional schematic of the present invention according to the plane body.
[figure number is to as directed]
Multitube trace dispenser 91 single hoses trace dispenser 92
Trace dispenser 93 bodys 94
Pipetting sleeve pipe 95 ports 951
Piston piece 96 micro-dispensers 10
Micro electronmechanical flow sensor 31 caulking grooves 141
Embodiment
See also Fig. 4, Fig. 5, the present invention's trace dispenser sensing apparatus is to include a micro-dispenser 10 and a sensing apparatus 30, this trace dispenser 10 is to include a body portion 11, operating portion 12 and body 13, wherein, this operating portion 12 is to can be the automatic operation of electronics or be manual operation, and this body 13 is to be single hose, if in multitube trace dispenser, then will have a plurality of bodys 13, below describe with single hose now, this body 13 is to include a tube wall 14 and an operating space 15, this operating space 15 is to be provided with a piston piece 16 starts in it, this piston piece 16 is to link a push rod 17 and be subjected to the interlock of a step motor (not shown), and under preferred embodiment, this operating space 15 is to be provided with on one, lower dead center (not shown) is to limit the start scope of this piston piece 16; The below of this body 13 is to be provided with the less socket pipe of a caliber 18, this socket pipe 18 is to be the taper body that down is the caliber convergent, and in addition, a pipetting sleeve pipe 19 is to be sheathed on this socket pipe 18, this pipetting sleeve pipe 19 is to be a taper body, and its bottom is provided with a port 191.
This sensing apparatus 30 is 15 interior appropriate locations, operating space of being located at this body 13, it includes a micro electronmechanical flow sensor 31, this micro electronmechanical flow sensor 31 is to be located on the tube wall 14 of this body 13, and be positioned at this operating space 15 relatively, in the middle of preferable enforcement, this micro electronmechanical flow sensor is the sensing flux chip that can comprise an integrated with CMOS amplifying circuit, its microstructure is by in the dark etched silicon groove (Cavity), deposit spathic silicon on the silicon groove (Polysilicon) forms a traversed by cantilever (Cross Bar), being covered with the thermoelectricity that is combined with silicon by aluminium around the cantilever constitutes array (Thermopiles array), this micro electronmechanical flow sensor 31 can be responded to the air that is caused by the flow field extruding in this operating space 15 and move, and can reach per second and how rise the monitoring of (nano-liter) yardstick air flow rate in normal atmospheric environment.Moreover, this micro electronmechanical flow sensor 31 can be noted down the liquid error amount that moves that senses, and can carry out quantitative test, thereby improve the fiduciary level of DNA quantitative experiment in conjunction with the real-time quantitative polymerization Enzyme interlock reactor (Real TimePCR Machine) of commercialization as DNA.
Aforementioned this sensing apparatus 30 mainly is to be located in the operating space 15 of this body 13, so that this sensing apparatus 30 energy perception gas displacement amount and variations in flow when these piston piece 16 starts, so in other embodiment, this sensing apparatus 30 also can combine with this piston piece 16, or is located at the below of this piston piece 16.
And for example shown in Figure 5, this sensing apparatus 30 is that the lower position of being located at the lower dead center A of relative this piston piece 16 in this operating space 15 (also can be located at other appropriate location, top position as the top dead centre of piston piece 16), when this trace dispenser 10 is operated and made piston piece 16 upwards during start, this sensing apparatus 30 can sense the correct flow of gas, displacement and because of variations in flow information airtight or that other mechanical actuation gap produces, and this information is passed to related receiving apparatus (not icon), get the liquid value in order to precision control, or further revised and take relevant revisal measure, reach the correct liquid value of getting with automatic feedback correcting mode.
Continuing sees also Fig. 6, Fig. 7, is further to be provided with a caulking groove 141 on the tube wall 14 of this body 13, and this caulking groove 141 is to supply being embedded of this sensing apparatus 30, in order to produce preferable sensing effect.
Continue and see also Fig. 8, be to be provided with a plane 142 on the tube wall 14 of this body 13, this plane 142 is the settings for this sensing apparatus 30, in preferable enforcement, this plane 142 is further to be provided with a caulking groove 143, and this caulking groove 143 is can be for the embedding setting of this sensing apparatus 30.
Because of being, the present invention is provided with this sensing apparatus by the appropriate location by the tube wall in the micro-dispenser body, can be by accurate correct flow change in displacement in this sensing apparatus perception trace dispenser, or the variations in flow information that is produced because of airtight problem or other mechanical actuation gap, make that recording correct drawing with the processing by this signal moves liquid measure, and then actively promote the control that degree of accuracy is gone up in micro-dispenser use.
In sum, the present invention's trace dispenser sensing apparatus is by its its specific structure feature, really can reach every requirement of former goal of the invention, and significantly improve the practical effect of existing product, more do not see the open or priority of use of the product that the same structure feature is arranged, the real establishment important document that has met patent of invention of obvious the present invention.The above only is preferred embodiment of the present invention, and the personage who is familiar with this case skill such as helps the equivalence of being done according to invention spirit of the present invention and modifies or variation, all should be encompassed in the application's claim.
Claims (10)
1. a micro-dispenser sensing apparatus is characterized in that, includes:
One micro-dispenser, this trace dispenser are to include a body portion, operating portion and at least one body, and this body is to have an operating space;
One sensing apparatus, this sensing apparatus are the appropriate locations of being located at this operating space in this body, and this sensing apparatus is to include a micro electronmechanical flow sensor, move but this micro electronmechanical flow sensor is a gas in this operating space of sensing.
2. micro-dispenser sensing apparatus as claimed in claim 1 is characterized in that, is to be provided with a piston piece in this operating space of described this body, and this piston piece is to link a push rod and be subjected to interlock.
3. micro-dispenser sensing apparatus as claimed in claim 1 is characterized in that, the below of described this body is to be provided with a socket pipe, and this socket pipe is can a sheathed pipetting sleeve pipe.
4. micro-dispenser sensing apparatus as claimed in claim 1 is characterized in that, described this body is to include in order to the tube wall of this sensing apparatus to be set.
5. micro-dispenser sensing apparatus as claimed in claim 1 is characterized in that, described this operating space is to have a upper and lower stop, and this sensing apparatus is the top position of being located at lower position or this top dead centre of this lower dead center.
6. micro-dispenser sensing apparatus as claimed in claim 4 is characterized in that, described this tube wall is further to be provided with one in order to be embedded the caulking groove of this sensing apparatus.
7. micro-dispenser sensing apparatus as claimed in claim 4 is characterized in that, described this tube wall is further to be provided with one in order to the plane of this sensing apparatus to be set.
8. micro-dispenser sensing apparatus as claimed in claim 7 is characterized in that, described this plane is to be provided with a caulking groove that supplies this sensing apparatus to set.
9. micro-dispenser sensing apparatus as claimed in claim 1, it is characterized in that, described this micro electronmechanical flow sensor is the sensing flux chip that comprises an integrated with CMOS amplifying circuit, its microstructure forms a traversed by cantilever by deposit spathic silicon on the dark etched silicon groove, is covered with the thermoelectricity that is combined with silicon by aluminium around this cantilever array is constituted.
10. micro-dispenser sensing apparatus as claimed in claim 1 is characterized in that, described this sensing apparatus is the below that is incorporated into this piston piece or is located at this piston piece.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510084329 CN1900680A (en) | 2005-07-18 | 2005-07-18 | Sensing device for micro quanlity split injector |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510084329 CN1900680A (en) | 2005-07-18 | 2005-07-18 | Sensing device for micro quanlity split injector |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1900680A true CN1900680A (en) | 2007-01-24 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200510084329 Pending CN1900680A (en) | 2005-07-18 | 2005-07-18 | Sensing device for micro quanlity split injector |
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| CN (1) | CN1900680A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105018343A (en) * | 2015-07-09 | 2015-11-04 | 广州安能特化学科技有限公司 | Automated sample processing unit of original state microbial oil gas and hydrate exploration technology and automation workstation |
| CN105170202A (en) * | 2011-09-23 | 2015-12-23 | 美艾利尔瑞士公司 | System and apparatus for reactions |
| CN106525503A (en) * | 2016-12-01 | 2017-03-22 | 无锡艾科瑞思产品设计与研究有限公司 | Micropipettor for food detection |
-
2005
- 2005-07-18 CN CN 200510084329 patent/CN1900680A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105170202A (en) * | 2011-09-23 | 2015-12-23 | 美艾利尔瑞士公司 | System and apparatus for reactions |
| CN105170202B (en) * | 2011-09-23 | 2017-10-27 | 美艾利尔瑞士公司 | System and device for reaction |
| CN105018343A (en) * | 2015-07-09 | 2015-11-04 | 广州安能特化学科技有限公司 | Automated sample processing unit of original state microbial oil gas and hydrate exploration technology and automation workstation |
| CN106525503A (en) * | 2016-12-01 | 2017-03-22 | 无锡艾科瑞思产品设计与研究有限公司 | Micropipettor for food detection |
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