CN1899512A - Chinese herbal medicine paste for treating hard atrophic type dystrophy of vulva - Google Patents
Chinese herbal medicine paste for treating hard atrophic type dystrophy of vulva Download PDFInfo
- Publication number
- CN1899512A CN1899512A CNA2006100511591A CN200610051159A CN1899512A CN 1899512 A CN1899512 A CN 1899512A CN A2006100511591 A CNA2006100511591 A CN A2006100511591A CN 200610051159 A CN200610051159 A CN 200610051159A CN 1899512 A CN1899512 A CN 1899512A
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- herbal medicine
- chinese herbal
- vulva
- treatment
- dystrophy
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- 241000411851 herbal medicine Species 0.000 title claims abstract description 8
- 201000006669 vulvar dystrophy Diseases 0.000 title claims description 14
- 208000025254 Vulval disease Diseases 0.000 title claims description 7
- 239000002674 ointment Substances 0.000 claims abstract description 13
- DTGKSKDOIYIVQL-WEDXCCLWSA-N (+)-borneol Chemical compound C1C[C@@]2(C)[C@@H](O)C[C@@H]1C2(C)C DTGKSKDOIYIVQL-WEDXCCLWSA-N 0.000 claims description 5
- 241000628997 Flos Species 0.000 claims description 5
- 241000131808 Scolopendra Species 0.000 claims description 5
- 241000522620 Scorpio Species 0.000 claims description 5
- 239000009490 scorpio Substances 0.000 claims description 5
- 230000000694 effects Effects 0.000 abstract description 9
- 231100000331 toxic Toxicity 0.000 abstract description 3
- 230000002588 toxic effect Effects 0.000 abstract description 3
- 230000008901 benefit Effects 0.000 abstract description 2
- 235000013399 edible fruits Nutrition 0.000 abstract 2
- 244000061520 Angelica archangelica Species 0.000 abstract 1
- 244000020518 Carthamus tinctorius Species 0.000 abstract 1
- 235000003255 Carthamus tinctorius Nutrition 0.000 abstract 1
- 244000241463 Cullen corylifolium Species 0.000 abstract 1
- 235000001287 Guettarda speciosa Nutrition 0.000 abstract 1
- 241000735234 Ligustrum Species 0.000 abstract 1
- 240000001341 Reynoutria japonica Species 0.000 abstract 1
- 235000018167 Reynoutria japonica Nutrition 0.000 abstract 1
- 210000004392 genitalia Anatomy 0.000 abstract 1
- 235000012907 honey Nutrition 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 description 9
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 9
- 239000003814 drug Substances 0.000 description 8
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 230000001684 chronic effect Effects 0.000 description 3
- 230000007812 deficiency Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 230000003902 lesion Effects 0.000 description 3
- 206010061218 Inflammation Diseases 0.000 description 2
- 239000002552 dosage form Substances 0.000 description 2
- 230000003203 everyday effect Effects 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000004054 inflammatory process Effects 0.000 description 2
- 208000002741 leukoplakia Diseases 0.000 description 2
- 230000002175 menstrual effect Effects 0.000 description 2
- 230000001575 pathological effect Effects 0.000 description 2
- 229960003604 testosterone Drugs 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 206010020880 Hypertrophy Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 208000032023 Signs and Symptoms Diseases 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000001363 autoimmune Effects 0.000 description 1
- 238000001574 biopsy Methods 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 230000004069 differentiation Effects 0.000 description 1
- 238000011156 evaluation Methods 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 229940088597 hormone Drugs 0.000 description 1
- 239000005556 hormone Substances 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 210000004185 liver Anatomy 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 230000001338 necrotic effect Effects 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 231100000915 pathological change Toxicity 0.000 description 1
- 230000036285 pathological change Effects 0.000 description 1
- 208000037920 primary disease Diseases 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
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- Medicines Containing Plant Substances (AREA)
Abstract
The Chinese herbal medicine ointment for treating hard atrophic genital vulval dystrophy is prepared with safflower, privet fruit, angelica, fleece flower root, malaytea scurfpea fruit and other six kinds of Chinese medicinal materials and honey in certain weight proportion. The present invention has the advantages of determined curative effect, convenient use, no known toxic side effect, etc.
Description
Technical field:
The present invention relates to a kind of Chinese herbal medicine unguentum for the treatment of hard atrophic type dystrophy of vulva, belong to the technical field of herbal pharmaceutical.
Background technology:
Chronic vulvar dystrophy (chronic vulvar dystrophy) has another name called leukoplakia vulvae (leukoplakiavulvae), is gynecological's common disease.Chronic vulvar dystrophy can be divided into three types by histopathology, i.e. hypertrophy type, hard atrophic type and mixed type.At present, underfed treatment lacks special method and medicine to pudendum, is one of difficult point of gynecological clinic treatment.Simultaneously, because companion atypical hyperplasia person has potential canceration possibility, so this disease is regarded as the precancerous lesion of pudendum (referring to 1.Djurdjcvic S always, Segedi D, Vejnovic T, et al.Modern approach to classification of precancerous conditionand vulvar dystrophy.Med pregl.1995; 48 (11-12): 399～404.2.micheletti L, Borgno G, Barbero M, et al.Cellular atypia in vulvar dystrophies.J Rrprod Med.1998, jun; 33 (6): 539～541.).The cause of disease and the pathogeny of vulvar dystrophy it be unclear that so far, doctor trained in Western medicine think with local inflammation or non-inflammation stimulation, inherited genetic factors, autoimmune, whole body and local hormone change relevant (referring to: 1. Le Jie edits. obstetrics and gynecology..People's Health Publisher .1998; Second edition: 243.2. Lian Lijuan chief editor. the skilful young gynecological oncology of woods. People's Health Publisher .1996; 179-182.).The traditional Chinese medical science is with primary disease ownership " pudendal pruritus " category, to this disease the comparatively ripe perfect theory of a cover arranged, with its dialectical for " deficiency of both the liver and kidney, deficiency of spleen-YANG and kidneyYANG, damp-heat accumulation " three card (referring to 1. Liu Lanfang chief editor. the department of obstetrics and gynecology difficult miscellaneous diseases. the medical officer people publishes .1999; 59.2. Liang Yongcai chief editor. gynecology examination and treatment is smart to be wanted. and the medical officer people publishes edition .1999 of society; 244).The treatment aspect lacks ripe effective method so far, thereby makes this disease become one of difficult point of gyniatrics.Doctor trained in Western medicine adopts composite treatment such as medicine, physics and operative treatment, weak curative effect, easily recurrence (referring to: 1. Meng Wei, Liang Xuelin chief editor. the department of obstetrics and gynecology handbook. the .1999 of Liaoning Science Press; 24.2. Mi Ruoran chief editor. the obstetrical and gynecological disease diagnoses and treatment. the Chinese Medicine science and technology .2000 of publishing house; Front page: 619.3.Ayhan A, Tuncer ZS, Kaya H.Vulvardystrophy:an evaluation of 285cases.Eur J Gynaeclo Oncol.1997; 18 (2): 139.).Many methods due to illness people can not be accepted or be difficult to stand the misery of treatment and sew and control.The traditional Chinese medical science adopts determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs, and curative effect varies with each individual, and changes greatlyyer, and will follow principle of individuation, lacks special-purpose patent medicine, has limited it in Clinical Application.
Summary of the invention:
The objective of the invention is: according to Traditional Chinese medical theory, clinical and pathological characteristic according to hard atrophic type dystrophy of vulva, provide a kind of and have curative effect certainly, prescription, dosage form are fixed, easy to use, not needing does not have the Chinese recipe of known toxic and side effects, to overcome the deficiencies in the prior art with characteristics such as disease plus-minuss.
The present invention constitutes like this: it is to use Flos Carthami 10-20g, Fructus Ligustri Lucidi 10-20g, Radix Angelicae Sinensis 10-20g, Radix Polygoni Multiflori 10-20g, Fructus Psoraleae 15-25g, Borneolum Syntheticum 2-4g, Herba speranskiae tuberculatae 15-25g, Rhizoma Polygonati 10-20g, Radix Angelicae Dahuricae 15-25g, 5 of Scolopendras, Scorpio 5-15g adds 150-300g Mel again through mechanical fine grinding and is made into unguentum.
Making a kind of preferred plan for the treatment of the Chinese herbal medicine unguentum of hard atrophic type dystrophy of vulva of the present invention is: it is by Flos Carthami 15g, Fructus Ligustri Lucidi 15g, Radix Angelicae Sinensis 15g, Radix Polygoni Multiflori 15g, Fructus Psoraleae 20g, Borneolum Syntheticum 3g, Herba speranskiae tuberculatae 20g, Rhizoma Polygonati 15g, Radix Angelicae Dahuricae 20g, 5 of Scolopendras, Scorpio 10g adds 200g Mel again through mechanical fine grinding and is made into unguentum.
Owing to adopted technique scheme, the present invention is made through theory of Chinese medical science scientific composition and repetition test by multiple Chinese herbal medicine and Mel, has the effect of " activating blood circulation to dissipate blood stasis, removing the necrotic tissue and promoting granulation ".Clinical research shows, uses through the diseased region external application, and its cure rate is 83.87%, and effective percentage is 12.90%, and total effective rate is 96.77%.And have prescription, dosage form is fixed, and is easy to use, not needing does not have the advantage of known toxic and side effects with characteristics such as disease plus-minuss.
Below two tables be respectively the present invention and treat 80 routine patients' the clinical treatment of leukoplakia vulvae contrast table and 80 routine patients add up to each grade Ridit value computer chart of data as a result, wherein matched group is treated all capable pathological changes vulvar sample pathological biopsy of preceding patient and is confirmed and typing for to use PIKANG SHUANG and 2% testosterone ointment to replace external curing to patient.Clean pudendum with clear water before sleeping and dry, be applied to the pudendum lesion in right amount, remove menstrual phase with the present invention, equal medication every day, 1 month is a course of treatment.
Table 1 80 routine patient are contrast table as a result
| Group | Cure | Effectively | Invalid | Worsen | Total effective rate | Add up to |
| Treatment group matched group * | 52(83.87％) 0(0.00％) | 8(12.90％) 11(61.11％) | 2(3.22％) 4(22.22％) | 0(0.00％) 3(16.67％) | 96.77％ 66.67％ | 62 18 |
* annotate: PIKANG SHUANG and 2% testosterone ointment replace external
Table 2 80 routine patients add up to each grade Ridit value computer chart of data
| Curative effect grade (1) | Treatment group (2) | Matched group (3) | Add up to (4) | (4)/2 (5) | (4) accumulative total moves down lattice (6) | (5)+(6) (7) | R＝(7)/N (8) |
| Worsen invalid effective healing | 0 2 8 52 | 3 4 11 0 | 3 6 19 52 | 1.5 3 9.5 26 | 0 3 9 28 | 1.5 6 16.5 54 | 0.0187 0.0750 0.2063 0.6750 |
| Add up to | 62 | 18 | 80(N) |
R
The treatment group=0.6008 R
Matched group=0.1459 u=5.91 p＜0.01
The specific embodiment:
Embodiments of the invention: get Flos Carthami 15g, Fructus Ligustri Lucidi 15g, Radix Angelicae Sinensis 15g, Radix Polygoni Multiflori 15g, Fructus Psoraleae 20g, Borneolum Syntheticum 3g, Herba speranskiae tuberculatae 20g, Rhizoma Polygonati 15g, Radix Angelicae Dahuricae 20g, 5 of Scolopendras, Scorpio 10g adds 200g Mel again and is made into unguentum earlier through mechanical fine grinding.
The usage of its finished product: clean pudendum with clear water before sleeping and dry, be applied to the pudendum lesion in right amount, remove menstrual phase with the present invention, equal medication every day, 1 month is a course of treatment.
Claims (2)
1, a kind of Chinese herbal medicine unguentum for the treatment of hard atrophic type dystrophy of vulva, it is characterized in that: it is to use Flos Carthami 10-20g, Fructus Ligustri Lucidi 10-20g, Radix Angelicae Sinensis 10-20g, Radix Polygoni Multiflori 10-20g, Fructus Psoraleae 15-25g, Borneolum Syntheticum 2-4g, Herba speranskiae tuberculatae 15-25g, Rhizoma Polygonati 10-20g, Radix Angelicae Dahuricae 15-25g, Scolopendra 3-7 bar, Scorpio 5-15g add 150-300g Mel again through mechanical fine grinding and are made into unguentum.
2, according to a kind of Chinese herbal medicine unguentum for the treatment of hard atrophic type dystrophy of vulva of claim 1, it is characterized in that: it is by Flos Carthami 15g, Fructus Ligustri Lucidi 15g, Radix Angelicae Sinensis 15g, Radix Polygoni Multiflori 15g, Fructus Psoraleae 20g, Borneolum Syntheticum 3g, Herba speranskiae tuberculatae 20g, Rhizoma Polygonati 15g, Radix Angelicae Dahuricae 20g, 5 of Scolopendras, Scorpio 10g adds 200g Mel again through mechanical fine grinding and is made into unguentum.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100511591A CN100534495C (en) | 2006-07-26 | 2006-07-26 | Chinese herbal medicine paste for treating hard atrophic type dystrophy of vulva |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2006100511591A CN100534495C (en) | 2006-07-26 | 2006-07-26 | Chinese herbal medicine paste for treating hard atrophic type dystrophy of vulva |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1899512A true CN1899512A (en) | 2007-01-24 |
| CN100534495C CN100534495C (en) | 2009-09-02 |
Family
ID=37655623
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB2006100511591A Expired - Fee Related CN100534495C (en) | 2006-07-26 | 2006-07-26 | Chinese herbal medicine paste for treating hard atrophic type dystrophy of vulva |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN100534495C (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102895507A (en) * | 2012-10-19 | 2013-01-30 | 高峰 | Chinese medicine for treating leukoplakia vulvae and preparation method thereof |
| CN104398791A (en) * | 2014-09-03 | 2015-03-11 | 遵义市妇女儿童医院 | Medicine for treating vulvar lichen sclerosus and preparation method and application thereof |
| CN112641881A (en) * | 2020-12-24 | 2021-04-13 | 肖雁冰 | Chinese herbal medicine ointment for treating leukoplakia vulvae |
-
2006
- 2006-07-26 CN CNB2006100511591A patent/CN100534495C/en not_active Expired - Fee Related
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102895507A (en) * | 2012-10-19 | 2013-01-30 | 高峰 | Chinese medicine for treating leukoplakia vulvae and preparation method thereof |
| CN104398791A (en) * | 2014-09-03 | 2015-03-11 | 遵义市妇女儿童医院 | Medicine for treating vulvar lichen sclerosus and preparation method and application thereof |
| CN112641881A (en) * | 2020-12-24 | 2021-04-13 | 肖雁冰 | Chinese herbal medicine ointment for treating leukoplakia vulvae |
Also Published As
| Publication number | Publication date |
|---|---|
| CN100534495C (en) | 2009-09-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C41 | Transfer of patent application or patent right or utility model | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20070202 Address after: No. 143, Dalian Road, Zunyi, Guizhou Applicant after: Attached Hospital of Zunyi Medical College Address before: Department of gynaecology, Dalian Road Medical College, Zunyi, Guizhou Applicant before: Xiao Yanbing Co-applicant before: Sun Lijun Co-applicant before: Jiang Changgui Co-applicant before: Yang Bing |
|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20090902 Termination date: 20180726 |
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| CF01 | Termination of patent right due to non-payment of annual fee |