CN1893977B - 以ep4激动剂为活性成分的治疗与骨质损失有关的疾病的药物 - Google Patents

以ep4激动剂为活性成分的治疗与骨质损失有关的疾病的药物 Download PDF

Info

Publication number
CN1893977B
CN1893977B CN02816932.8A CN02816932A CN1893977B CN 1893977 B CN1893977 B CN 1893977B CN 02816932 A CN02816932 A CN 02816932A CN 1893977 B CN1893977 B CN 1893977B
Authority
CN
China
Prior art keywords
acid
chemical compound
azepine
hydroxyl
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CN02816932.8A
Other languages
English (en)
Chinese (zh)
Other versions
CN1893977A (zh
Inventor
丸山透
小林馨
神户透
丸山隆幸
吉田秀行
阿部信贵
西浦昭雄
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ono Pharmaceutical Co Ltd
Original Assignee
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ono Pharmaceutical Co Ltd filed Critical Ono Pharmaceutical Co Ltd
Priority claimed from PCT/JP2002/007385 external-priority patent/WO2003009872A1/ja
Publication of CN1893977A publication Critical patent/CN1893977A/zh
Application granted granted Critical
Publication of CN1893977B publication Critical patent/CN1893977B/zh
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Landscapes

  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
CN02816932.8A 2001-07-23 2002-07-22 以ep4激动剂为活性成分的治疗与骨质损失有关的疾病的药物 Expired - Fee Related CN1893977B (zh)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
JP2001222148 2001-07-23
JP222148/2001 2001-07-23
JP239895/2001 2001-08-07
JP2001239895 2001-08-07
JP56449/2002 2002-03-01
JP2002056449 2002-03-01
PCT/JP2002/007385 WO2003009872A1 (en) 2001-07-23 2002-07-22 Remedies for diseases with bone mass loss having ep4 agonist as the active ingredient

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN2010102514340A Division CN101921220B (zh) 2001-07-23 2002-07-22 治疗与骨质损失有关的疾病的含有ep4激动剂作为活性成分的药物组合物

Publications (2)

Publication Number Publication Date
CN1893977A CN1893977A (zh) 2007-01-10
CN1893977B true CN1893977B (zh) 2012-12-05

Family

ID=34587092

Family Applications (1)

Application Number Title Priority Date Filing Date
CN02816932.8A Expired - Fee Related CN1893977B (zh) 2001-07-23 2002-07-22 以ep4激动剂为活性成分的治疗与骨质损失有关的疾病的药物

Country Status (2)

Country Link
CN (1) CN1893977B (es)
ES (1) ES2360604T3 (es)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000003980A1 (fr) * 1998-07-15 2000-01-27 Ono Pharmaceutical Co., Ltd. DERIVES DE PHENYL-POSTAGLANDINE E 5-THIA-φ-SUBSTITUES, PROCEDE DE PRODUCTION DESDITS DERIVES ET MEDICAMENTS CONTENANT LESDITS DERIVES EN TANT QUE PRINCIPE ACTIF
CN1269721A (zh) * 1997-09-09 2000-10-11 普罗特和甘保尔公司 用非天然存在的fp选择性激动剂增加骨容量的方法
WO2001046140A1 (en) * 1999-12-22 2001-06-28 Pfizer Products Inc. Ep4 receptor selective agonists in the treatment of osteoporosis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1269721A (zh) * 1997-09-09 2000-10-11 普罗特和甘保尔公司 用非天然存在的fp选择性激动剂增加骨容量的方法
WO2000003980A1 (fr) * 1998-07-15 2000-01-27 Ono Pharmaceutical Co., Ltd. DERIVES DE PHENYL-POSTAGLANDINE E 5-THIA-φ-SUBSTITUES, PROCEDE DE PRODUCTION DESDITS DERIVES ET MEDICAMENTS CONTENANT LESDITS DERIVES EN TANT QUE PRINCIPE ACTIF
WO2001046140A1 (en) * 1999-12-22 2001-06-28 Pfizer Products Inc. Ep4 receptor selective agonists in the treatment of osteoporosis

Also Published As

Publication number Publication date
CN1893977A (zh) 2007-01-10
ES2360604T3 (es) 2011-06-07

Similar Documents

Publication Publication Date Title
CN101921220B (zh) 治疗与骨质损失有关的疾病的含有ep4激动剂作为活性成分的药物组合物
RU2306309C2 (ru) Производное 8-азапростагландина, фармацевтическая композиция, агент для профилактики заболеваний
JP4582456B2 (ja) 8−アザプロスタグランジン誘導体およびその医薬用途
EP1785421A1 (en) Tropan compound
CN1893977B (zh) 以ep4激动剂为活性成分的治疗与骨质损失有关的疾病的药物
JP2005104836A (ja) プロスタグランジン誘導体

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C14 Grant of patent or utility model
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20121205

Termination date: 20170722

CF01 Termination of patent right due to non-payment of annual fee