CN1882319B - 抗肿瘤萜类化合物 - Google Patents

抗肿瘤萜类化合物 Download PDF

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Publication number
CN1882319B
CN1882319B CN2004800336500A CN200480033650A CN1882319B CN 1882319 B CN1882319 B CN 1882319B CN 2004800336500 A CN2004800336500 A CN 2004800336500A CN 200480033650 A CN200480033650 A CN 200480033650A CN 1882319 B CN1882319 B CN 1882319B
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CN
China
Prior art keywords
cells
cancer
extract
myrrh
ocimene
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
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CN2004800336500A
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English (en)
Chinese (zh)
Other versions
CN1882319A (zh
Inventor
艾弗·德尔姆·鲍恩
艾哈迈德·亚西涅·阿里
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Compton Developments Ltd
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Compton Developments Ltd
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Publication of CN1882319A publication Critical patent/CN1882319A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A61K31/015—Hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
CN2004800336500A 2003-11-13 2004-11-12 抗肿瘤萜类化合物 Expired - Fee Related CN1882319B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GBGB0326518.8A GB0326518D0 (en) 2003-11-13 2003-11-13 Anti-cancer compounds
GB0326518.8 2003-11-13
PCT/GB2004/004769 WO2005049001A1 (en) 2003-11-13 2004-11-12 Anti-tumour terpene compounds

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CN201010205334A Division CN101862365A (zh) 2003-11-13 2004-11-12 抗肿瘤萜类化合物

Publications (2)

Publication Number Publication Date
CN1882319A CN1882319A (zh) 2006-12-20
CN1882319B true CN1882319B (zh) 2010-08-25

Family

ID=29726508

Family Applications (2)

Application Number Title Priority Date Filing Date
CN2004800336500A Expired - Fee Related CN1882319B (zh) 2003-11-13 2004-11-12 抗肿瘤萜类化合物
CN201010205334A Pending CN101862365A (zh) 2003-11-13 2004-11-12 抗肿瘤萜类化合物

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201010205334A Pending CN101862365A (zh) 2003-11-13 2004-11-12 抗肿瘤萜类化合物

Country Status (12)

Country Link
US (1) US20070259056A1 (https=)
EP (1) EP1682107B1 (https=)
JP (1) JP2007511492A (https=)
KR (1) KR20060121177A (https=)
CN (2) CN1882319B (https=)
AT (1) ATE439126T1 (https=)
AU (1) AU2004290946B2 (https=)
CA (1) CA2545717A1 (https=)
DE (1) DE602004022578D1 (https=)
DK (1) DK1682107T3 (https=)
GB (1) GB0326518D0 (https=)
WO (1) WO2005049001A1 (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101849981B (zh) * 2010-06-22 2011-11-23 南京中医药大学 一种具有抗妇科肿瘤作用的没药有效部位及其制备方法和其应用
WO2012033634A2 (en) 2010-09-09 2012-03-15 Mary Kay Inc. Topical skin care formulations comprising plant extracts
WO2018144954A1 (en) * 2017-02-03 2018-08-09 City Of Hope Silica nanoparticle with an insoluble drug
WO2020033567A1 (en) * 2018-08-07 2020-02-13 University Of Florida Research Foundation Methods and compositions for substituted arylcycloheptane analogs
CN110960518B (zh) * 2019-12-31 2022-12-20 河南大学 金丝大菊提取物在制备抗肿瘤药物中的应用

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5190979A (en) * 1988-06-24 1993-03-02 Stephen Herman Ozonides of terpenes and their medical uses
US6350784B1 (en) * 1996-02-12 2002-02-26 Meryl J. Squires Antimicrobial prevention and treatment of human immunedeficiency virus and other infectious diseases
US5602184A (en) * 1993-03-03 1997-02-11 The United States Of America As Represented By Department Of Health And Human Services Monoterpenes, sesquiterpenes and diterpenes as cancer therapy
US5876728A (en) * 1995-02-15 1999-03-02 Howard David Kass Natural composition extracted from plants used in the treatment of cancer
AUPO316796A0 (en) * 1996-10-23 1996-11-14 Hood, John James David Essential oil
US6464839B1 (en) 1997-04-14 2002-10-15 Yuan Da International Group Limited Beta-elemene, method to prepare the same and uses thereof
US6265639B1 (en) * 1998-01-22 2001-07-24 Washington State University Foundation Gymnosperm nucleic acid molecules encoding sesquiterpene synthases and methods of use
FR2808196A1 (fr) 2000-04-27 2001-11-02 Andre Rougereau Nouveaux medicaments a base de melanges de sesquiterpenes
FR2811899B1 (fr) * 2000-07-20 2003-02-07 Anne Marie Pierrette Giraud Association d'huiles essentielles et applications therapeutiques
US6486706B2 (en) 2000-12-06 2002-11-26 Intel Corporation Domino logic with low-threshold NMOS pull-up
EP1351678A2 (en) * 2001-01-02 2003-10-15 Elizabeth Shanahan-Prendergast Treatment for inhibiting neoplastic lesions using incensole and/or furanogermacrens
WO2002080951A1 (en) * 2001-04-06 2002-10-17 Synergistix Biotech, Inc. Herbal extracts for the treatment of cancer
GB0210152D0 (en) * 2002-05-02 2002-06-12 Compton Developments Ltd Use of plant materials
EP1587482A4 (en) * 2003-01-31 2010-08-25 Technion Res & Dev Foundation INFLAMMATORY COMPOSITIONS AND ITS USES
US20050074509A1 (en) * 2003-10-02 2005-04-07 Data Medica Padova S.P.A. Cancer treatment using natural plant products or essential oils extracted from some pistacia species or components

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Dana Tatman,et al.Volatile isoprenoid constituents of fruits，vegetables andherbs cumulatively suppress the proliferation of murine B16melanoma and human HL-60 leukemia cells.Cancer Letters175 2.2002,175(2),129-139. *
Saleh M M,et al.Cytotoxicity and in vitro effects on human cancer cell linesofvolatiles of Apium graveolens var.filicum.Pharmaceutical and Pharmacological Letters8 2.1994,8(2),97-99. *

Also Published As

Publication number Publication date
DE602004022578D1 (de) 2009-09-24
EP1682107B1 (en) 2009-08-12
DK1682107T3 (da) 2009-12-14
AU2004290946B2 (en) 2010-04-22
KR20060121177A (ko) 2006-11-28
WO2005049001A1 (en) 2005-06-02
CN1882319A (zh) 2006-12-20
US20070259056A1 (en) 2007-11-08
CN101862365A (zh) 2010-10-20
JP2007511492A (ja) 2007-05-10
ATE439126T1 (de) 2009-08-15
CA2545717A1 (en) 2005-06-02
AU2004290946A1 (en) 2005-06-02
GB0326518D0 (en) 2003-12-17
EP1682107A1 (en) 2006-07-26

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Granted publication date: 20100825

Termination date: 20101112