CN1879674A - Soft capsule preparation of angelica and preparation method thereof - Google Patents

Soft capsule preparation of angelica and preparation method thereof Download PDF

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Publication number
CN1879674A
CN1879674A CN 200510035176 CN200510035176A CN1879674A CN 1879674 A CN1879674 A CN 1879674A CN 200510035176 CN200510035176 CN 200510035176 CN 200510035176 A CN200510035176 A CN 200510035176A CN 1879674 A CN1879674 A CN 1879674A
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CN
China
Prior art keywords
soft capsule
preparation
capsule preparation
radix angelicae
angelicae sinensis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN 200510035176
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Chinese (zh)
Inventor
滕厚雷
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Haikou Luke South Drug Research & Development Co Ltd
Original Assignee
Haikou Luke South Drug Research & Development Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haikou Luke South Drug Research & Development Co Ltd filed Critical Haikou Luke South Drug Research & Development Co Ltd
Priority to CN 200510035176 priority Critical patent/CN1879674A/en
Publication of CN1879674A publication Critical patent/CN1879674A/en
Pending legal-status Critical Current

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  • Medicinal Preparation (AREA)

Abstract

The invention provides the process for preparing soft capsule from Chinese angelica root as the raw material through the steps of ultramicro disintegration and alcohol extraction.

Description

Soft capsule preparation of angelica and preparation method thereof
Technical field
The present invention relates to a kind of Chinese medicinal soft capsule preparation and preparation method thereof, said preparation is grouped into by working as.
Background technology
Radix Angelicae Sinensis Tabellae (WS3-B-3819-98) has been applied to clinical, is Chinese medicine preparation, is made by the Radix Angelicae Sinensis Herba indigoferae Pseudotinctoriae, and having enriches blood invigorates blood circulation menstruction regulating and pain relieving.Be used for the shallow complexion that blood deficiency causes, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation.
The Radix Angelicae Sinensis Tabellae disintegration time is long, again because Radix Angelicae Sinensis Tabellae contains the crude drug powder, and absorption difference, bioavailability is low, has influenced the Radix Angelicae Sinensis Tabellae curative effect.
The present invention makes soft Chinese angelica capsule by using ultramicro communication technique and soft capsule preparation Technology exactly, thereby the above defective of Radix Angelicae Sinensis Tabellae is given full play to its therapeutical effect.
Summary of the invention
The object of the present invention is to provide a kind of medicament composing prescription with Radix Angelicae Sinensis Tabellae is the new soft capsule preparation of angelica of foundation, and said preparation is grouped into by working as.
The invention provides a kind of preparation method of the soft capsule preparation of angelica of making by Radix Angelicae Sinensis.
Soft Chinese angelica capsule is characterised in that Radix Angelicae Sinensis earlier through micronizing, and then is used as medicine after alcohol extraction and makes soft capsule preparation.
The preparation method of soft Chinese angelica capsule provided by the invention is: get 1 weight portion active component and add in the 1-5 weight diluent, fully mixing utilizes the rubber compacting to form.
Diluent is to add an amount of suspending agent (Cera Flava, Petiolus Trachycarpi wet goods) in vegetable oil or the vegetable oil to form.The main component of rubber is gelatin, glycerol etc.
Below through detecting explanation beneficial effect of the present invention:
One, detects index and method
Disintegration: inspection technique disintegration (an appendix XII of Chinese Pharmacopoeia version in 2000 A) is checked
Two, commercially available Radix Angelicae Sinensis Tabellae disintegration time testing result: 28 minutes
Three, preparation example 1 sample disintegration time testing result is 12 minutes
The specific embodiment
Preparation example 1
With Radix Angelicae Sinensis 600g micronizing; Extract secondary with 70% alcohol heating reflux that is equivalent to 6 times of medical material amounts, each 2 hours, merge extractive liquid, filtered, and filtrate recycling ethanol also is condensed into thick paste, added in the 300g diluent and (added the 15g Cera Flava in the 285g soybean oil), and mixing is made medicinal liquid.Get the 500g gelatin, 150g glycerol and 500g water are made glue.Utilize pressing, make 1000 of soft capsules, promptly.

Claims (4)

1, a kind of enriching blood invigorated blood circulation, and the soft capsule preparation of menstruction regulating and pain relieving is characterized in that said preparation is to make when being classified as raw material.
2,, it is characterized in that Radix Angelicae Sinensis earlier through micronizing, and then after alcohol extraction, be used as medicine and make soft capsule preparation according to the soft capsule preparation of claim 1.
3, according to the soft capsule preparation of claim 1-2, the activity in the claim 2 is imitated composition, get 1 weight portion active component and add in the 1-5 weight diluent, fully mixing utilizes the rubber compacting to form.
4, according to the soft capsule preparation of claim 3, described diluent is to add an amount of suspending agent (Cera Flava, Petiolus Trachycarpi wet goods) in vegetable oil or the vegetable oil to form.The main component of rubber is gelatin, glycerol etc.
CN 200510035176 2005-06-13 2005-06-13 Soft capsule preparation of angelica and preparation method thereof Pending CN1879674A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 200510035176 CN1879674A (en) 2005-06-13 2005-06-13 Soft capsule preparation of angelica and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 200510035176 CN1879674A (en) 2005-06-13 2005-06-13 Soft capsule preparation of angelica and preparation method thereof

Publications (1)

Publication Number Publication Date
CN1879674A true CN1879674A (en) 2006-12-20

Family

ID=37518175

Family Applications (1)

Application Number Title Priority Date Filing Date
CN 200510035176 Pending CN1879674A (en) 2005-06-13 2005-06-13 Soft capsule preparation of angelica and preparation method thereof

Country Status (1)

Country Link
CN (1) CN1879674A (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102614233A (en) * 2011-01-31 2012-08-01 天明制药股份有限公司 Manufacturing method of microcapsule
CN104857202A (en) * 2015-02-03 2015-08-26 吉林省通化博祥药业股份有限公司 Preparation method of compound anti-cold softgel preparation

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102614233A (en) * 2011-01-31 2012-08-01 天明制药股份有限公司 Manufacturing method of microcapsule
CN102614233B (en) * 2011-01-31 2014-04-02 天明制药股份有限公司 Manufacturing method of microcapsule
CN104857202A (en) * 2015-02-03 2015-08-26 吉林省通化博祥药业股份有限公司 Preparation method of compound anti-cold softgel preparation
CN104857202B (en) * 2015-02-03 2019-09-20 吉林省通化博祥药业股份有限公司 A kind of preparation method of compounded anti-cold soft capsule preparation

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