CN1879674A - Soft capsule preparation of angelica and preparation method thereof - Google Patents
Soft capsule preparation of angelica and preparation method thereof Download PDFInfo
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- CN1879674A CN1879674A CN 200510035176 CN200510035176A CN1879674A CN 1879674 A CN1879674 A CN 1879674A CN 200510035176 CN200510035176 CN 200510035176 CN 200510035176 A CN200510035176 A CN 200510035176A CN 1879674 A CN1879674 A CN 1879674A
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- Prior art keywords
- soft capsule
- preparation
- capsule preparation
- radix angelicae
- angelicae sinensis
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Abstract
The invention provides the process for preparing soft capsule from Chinese angelica root as the raw material through the steps of ultramicro disintegration and alcohol extraction.
Description
Technical field
The present invention relates to a kind of Chinese medicinal soft capsule preparation and preparation method thereof, said preparation is grouped into by working as.
Background technology
Radix Angelicae Sinensis Tabellae (WS3-B-3819-98) has been applied to clinical, is Chinese medicine preparation, is made by the Radix Angelicae Sinensis Herba indigoferae Pseudotinctoriae, and having enriches blood invigorates blood circulation menstruction regulating and pain relieving.Be used for the shallow complexion that blood deficiency causes, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation.
The Radix Angelicae Sinensis Tabellae disintegration time is long, again because Radix Angelicae Sinensis Tabellae contains the crude drug powder, and absorption difference, bioavailability is low, has influenced the Radix Angelicae Sinensis Tabellae curative effect.
The present invention makes soft Chinese angelica capsule by using ultramicro communication technique and soft capsule preparation Technology exactly, thereby the above defective of Radix Angelicae Sinensis Tabellae is given full play to its therapeutical effect.
Summary of the invention
The object of the present invention is to provide a kind of medicament composing prescription with Radix Angelicae Sinensis Tabellae is the new soft capsule preparation of angelica of foundation, and said preparation is grouped into by working as.
The invention provides a kind of preparation method of the soft capsule preparation of angelica of making by Radix Angelicae Sinensis.
Soft Chinese angelica capsule is characterised in that Radix Angelicae Sinensis earlier through micronizing, and then is used as medicine after alcohol extraction and makes soft capsule preparation.
The preparation method of soft Chinese angelica capsule provided by the invention is: get 1 weight portion active component and add in the 1-5 weight diluent, fully mixing utilizes the rubber compacting to form.
Diluent is to add an amount of suspending agent (Cera Flava, Petiolus Trachycarpi wet goods) in vegetable oil or the vegetable oil to form.The main component of rubber is gelatin, glycerol etc.
Below through detecting explanation beneficial effect of the present invention:
One, detects index and method
Disintegration: inspection technique disintegration (an appendix XII of Chinese Pharmacopoeia version in 2000 A) is checked
Two, commercially available Radix Angelicae Sinensis Tabellae disintegration time testing result: 28 minutes
Three, preparation example 1 sample disintegration time testing result is 12 minutes
The specific embodiment
Preparation example 1
With Radix Angelicae Sinensis 600g micronizing; Extract secondary with 70% alcohol heating reflux that is equivalent to 6 times of medical material amounts, each 2 hours, merge extractive liquid, filtered, and filtrate recycling ethanol also is condensed into thick paste, added in the 300g diluent and (added the 15g Cera Flava in the 285g soybean oil), and mixing is made medicinal liquid.Get the 500g gelatin, 150g glycerol and 500g water are made glue.Utilize pressing, make 1000 of soft capsules, promptly.
Claims (4)
1, a kind of enriching blood invigorated blood circulation, and the soft capsule preparation of menstruction regulating and pain relieving is characterized in that said preparation is to make when being classified as raw material.
2,, it is characterized in that Radix Angelicae Sinensis earlier through micronizing, and then after alcohol extraction, be used as medicine and make soft capsule preparation according to the soft capsule preparation of claim 1.
3, according to the soft capsule preparation of claim 1-2, the activity in the claim 2 is imitated composition, get 1 weight portion active component and add in the 1-5 weight diluent, fully mixing utilizes the rubber compacting to form.
4, according to the soft capsule preparation of claim 3, described diluent is to add an amount of suspending agent (Cera Flava, Petiolus Trachycarpi wet goods) in vegetable oil or the vegetable oil to form.The main component of rubber is gelatin, glycerol etc.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200510035176 CN1879674A (en) | 2005-06-13 | 2005-06-13 | Soft capsule preparation of angelica and preparation method thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 200510035176 CN1879674A (en) | 2005-06-13 | 2005-06-13 | Soft capsule preparation of angelica and preparation method thereof |
Publications (1)
Publication Number | Publication Date |
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CN1879674A true CN1879674A (en) | 2006-12-20 |
Family
ID=37518175
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN 200510035176 Pending CN1879674A (en) | 2005-06-13 | 2005-06-13 | Soft capsule preparation of angelica and preparation method thereof |
Country Status (1)
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CN (1) | CN1879674A (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102614233A (en) * | 2011-01-31 | 2012-08-01 | 天明制药股份有限公司 | Manufacturing method of microcapsule |
CN104857202A (en) * | 2015-02-03 | 2015-08-26 | 吉林省通化博祥药业股份有限公司 | Preparation method of compound anti-cold softgel preparation |
-
2005
- 2005-06-13 CN CN 200510035176 patent/CN1879674A/en active Pending
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102614233A (en) * | 2011-01-31 | 2012-08-01 | 天明制药股份有限公司 | Manufacturing method of microcapsule |
CN102614233B (en) * | 2011-01-31 | 2014-04-02 | 天明制药股份有限公司 | Manufacturing method of microcapsule |
CN104857202A (en) * | 2015-02-03 | 2015-08-26 | 吉林省通化博祥药业股份有限公司 | Preparation method of compound anti-cold softgel preparation |
CN104857202B (en) * | 2015-02-03 | 2019-09-20 | 吉林省通化博祥药业股份有限公司 | A kind of preparation method of compounded anti-cold soft capsule preparation |
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Legal Events
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C06 | Publication | ||
PB01 | Publication | ||
C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
WD01 | Invention patent application deemed withdrawn after publication |