Summary of the invention
The purpose of this invention is to provide a kind of Chinese medicine composition with nourishing health function, another object of the present invention provides the preparation method of this product.
For achieving the above object, we have adopted following technical scheme:
Chinese medicine composition of the present invention is that the feedstock production by the following weight ratio forms:
Radix Adenophorae (Radix Glehniae) 2-30 part Semen Ziziphi Spinosae 2-30 part Ganoderma 2-30 part Fructus Jujubae 2-30 part medicine fennel 4-40 part Pericarpium Citri Reticulatae 4-40 part
Radix Rehmanniae Preparata 4-40 part Radix Paeoniae Alba 4-40 part Rhizoma Chuanxiong 2-30 part Radix Saposhnikoviae 2-30 part Radix Gentianae Macrophyllae 2-30 part Radix Clematidis 2-30 part
Fructus Chaenomelis 2-30 part Cortex Eucommiae 2-30 part Radix Peucedani 2-30 part Rhizoma Polygonati Odorati 2-30 part Radix Achyranthis Bidentatae 2-30 part Cortex cinnamomi japonici (Ramulus Cinnamomi) 2-30 part
Massa Medicata Fermentata 2-30 part Radix Glycyrrhizae 2-30 part Fructus Lycii 2-30 part Rhizoma Et Radix Notopterygii 2-30 part.
The weight ratio of the raw material of preparation Chinese medicine composition of the present invention can be preferably:
Radix Adenophorae (Radix Glehniae) 5-15 part Semen Ziziphi Spinosae 5-15 part Ganoderma 5-15 part Fructus Jujubae 5-15 part medicine fennel 8-25 part Pericarpium Citri Reticulatae 8-25 part
Radix Rehmanniae Preparata 8-25 part Radix Paeoniae Alba 8-25 part Rhizoma Chuanxiong 5-15 part Radix Saposhnikoviae 5-15 part Radix Gentianae Macrophyllae 5-15 part Radix Clematidis 5-15 part
Fructus Chaenomelis 5-15 part Cortex Eucommiae 5-15 part Radix Peucedani 5-15 part Rhizoma Polygonati Odorati 5-15 part Radix Achyranthis Bidentatae 5-15 part Cortex cinnamomi japonici (Ramulus Cinnamomi) 5-15 part
Massa Medicata Fermentata 5-15 part Radix Glycyrrhizae 5-15 part Fructus Lycii 5-15 part Rhizoma Et Radix Notopterygii 5-15 part.
The weight ratio of the raw material of preparation Chinese medicine composition of the present invention can be preferably:
15 parts of 15 parts of Pericarpium Citri Reticulataes of 10 parts of medicine fennels of 10 portions of Fructus Jujubaes of 10 portions of Ganodermas of 10 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
10 parts of 10 parts of Radix Clematidis of 10 portions of Radix Gentianae Macrophyllae of 10 parts of Radix Saposhnikoviaes of 15 parts of Rhizoma Chuanxiongs of 15 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
10 parts on 10 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 10 parts of Radix Achyranthis Bidentataes of 10 portions of Rhizoma Polygonati Odorati of 10 parts of Radix Peucedanis of 10 parts of Cortexs Eucommiae of Fructus Chaenomelis
10 parts of 10 portions of Rhizoma Et Radix Notopterygiis of 10 portions of Fructus Lyciis of 10 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata.
Chinese medicine composition of the present invention, the various dosage forms of the clinical acceptance of preparation process preparation becoming that can be by routine are as: granule, tablet, pill, capsule, oral liquid, tincture, medicated wine, mixture, powder with for medicated wine etc.
Medicated wine preparation technology of the present invention is:
Get each medical material in the Chinese medicine composition, processes is concocted routinely, puts in airtight the porcelain altar or other appropriate vessel, add Chinese liquor or wine base 4-20 and doubly measure, airtight dipping 30-200 day, take out immersion, the squeezing medicinal residues, press liquor and immersion merge, with sucrose or sweeting agent stirring and dissolving, adding water prepares in right amount, airtight, leave standstill a couple of days, filter, fill, promptly.
Medicated wine preparation technology of the present invention also can be:
Get each medical material in the Chinese medicine composition, processes is concocted routinely, puts in the close container that lid arranged, add Chinese liquor or wine base 4-20 and doubly measure, heating is after treating that wine is little and boiling, soak 30-200 day, take out immersion, the squeezing medicinal residues, press liquor and immersion merge, and with sucrose or sweeting agent stirring and dissolving, add water and prepare in right amount, airtight, leave standstill a couple of days, filter, fill, promptly.
Pharmaceutical composition of the present invention, good effect, toxic and side effects are few.Be the therapeutical effect and the toxic and side effects that show medicine of the present invention, we have done a large amount of experimentatioies, below experimental example be used to further specify the present invention.
Preparation of the present invention is to effect of immunologic function
Test objective: observe immunoregulation effect of the present invention.
Group and dosage:
Tried thing preparation of the present invention (test specimen is 10 times of concentrated solutions), 50% ethanol, southern Shandong pharmacy group provides.To be tried thing with distilled water and ethanol during test and be mixed with variable concentrations.
The laboratory animal Kunming mouse, female, body weight 18~22g Shandong Medical University medical experiment animal center provides.
Reagent and instrument: concanavalin A, Con A [CONA] (SIGMA company product), RPMI1640 culture fluid, tetrazolium bromide (MTT) microplate reader, inverted microscope and blood cell automatic counter for counting.
(1) the blank group gives isopyknic distilled water.
(2) the solvent control group gives the ethanol of equal-volume 50%.
(3) positive controls is produced (being equivalent to recommend every day 10 times of consumptions) by CN200410035979 embodiment 1.
(4) low dose group of the present invention: injection preparation of the present invention (being equivalent to recommend every day 5 times of consumptions).
(5) dosage group among the present invention: injection preparation of the present invention (being equivalent to recommend every day 10 times of consumptions).
(6) high dose group of the present invention: injection preparation of the present invention (being equivalent to recommend every day 20 times of consumptions).
Experimental implementation:
Method according to " health food check and technology assessment standard " (2003) regulation is divided into 6 groups with 300 female Kunming mouses by body weight, 50 every group at random.Adopt the per os administration by gavage to be tried thing, irritate stomach, once a day, continuous 30 days, the blank group gives isopyknic distilled water, positive controls 1 gives the ethanol of equal-volume 50%, and positive controls 2 is produced (being equivalent to recommend every day 10 times of consumptions) by CN200410035979 embodiment 1, and the basic, normal, high dosage group of the present invention is measured each experimental index testing index respectively after last is irritated stomach.
Statistical method is used SPSS 11.0forwindows software, adopts the statistical method of one factor analysis of variance and t check.
Experimental result:
1, concanavalin A, Con A [CONA] inducing mouse splenocyte conversion test
MTT is resolved into the crystalline optical density difference of first as criterion.The result shows that the ability that the experimental mice splenocyte changes into blast cell strengthens than blank group mice, and wherein positive controls, height, middle dosage prescription difference statistics have utmost point significant difference (P<0.01), see Table 1.Experimental result shows: suitably the present invention of dosage can the non-conversion capability that strengthens the normal mouse splenocyte specifically.
Table 1 the present invention promotes normal mouse splenocyte transformation experiment
Group | Optical density difference (X ± SD) |
Dosage group high dose group of the present invention among the low dose group the present invention of the present invention of blank group positive controls solvent control group | 0.015±0.006 0.016±0.002 0.030±0.004
** 0.022±0.005 0.031±0.003
** 0.038±0.007
** |
Annotate:
*Expression is compared P<0.01 with the blank group;
*Expression is compared P<0.05 with the blank group
2, the present invention promotes the anti-sheep red blood cell (SRBC) antibody response of normal mouse
The serum hemolysin antibody product of the anti-sheep red blood cell (SRBC) of experimental mice has raising in various degree than blank group mice, and wherein high, middle dosage group mice has utmost point significant difference (P<0.01) than blank group mice; The low dose group mice has notable difference (P<0.05) than blank group mice variance statistics.And dosage group and solvent control group do not have notable difference among the present invention.This explanation the present invention can strengthen the humoral immunization ability of normal mouse to specific antigen specifically.Result such as table 2.
Table 2 the present invention is to the influence of macrophage phagocytosis of mice (x ± s)
Group | Serum hemolysin (X ± SD) |
Dosage group high dose group of the present invention among the low dose group the present invention of the present invention of blank group solvent control group positive controls | 65.4±16.7 54.6±3.4 85.5±7.4
** 77.9±11.1
* 88.3±9.4
** 107.2±8.6
** |
Annotate:
*Expression is compared P<0.01 with the blank group;
*Expression is compared P<0.05 with the blank group
3, the present invention promotes normal mouse to remove the particulate ability of carbon element
The ability that each dosage group of the present invention and positive controls mice are removed a carbon element material than blank group mice strengthens in various degree, be reflected at phagocytic index and compared enhancing in various degree than matched group, wherein high, middle dosage group has significant difference (P<0.05) than the blank group; The low dose group mice sees Table 3 than blank group mice difference not obvious (P>0.05).Endothelial system is one of important indicator of body cell immunologic function to foreign bodies removal speed (phagocytic index).This experimental result shows that the present invention who takes suitable dosage can obviously promote the cellular immune function of normal mouse.
Table 3 the present invention removes the influence of the particulate ability of carbon element to normal mouse
Group | Phagocytic index (X ± SD) |
Dosage group high dose group of the present invention among the low dose group the present invention of the present invention of blank group solvent control group positive controls | 3.52±0.27 3.47±0.46 3.96±0.16 3.67±0.42 4.06±0.35
* 5.69±0.57
* |
Annotate:
*Expression is compared P<0.05 with the blank group
Preparation of the present invention is to the influence of life span of drosophila melanogaster
Method is with reference to " the health food function assessment assessment process and the method for inspection " Ministry of Public Health health supervision department. health food laws and regulations on the management compilation. and the 2nd edition. Changchun: Jilin science tech publishing house, 1998,41 186
Laboratory animal wild type Oregon K strain Drosophila melanogaster (Drosophila melanogaster)
Experimental technique is collected the adult of the not copulation of newly sprouting wings in the 8h, male and female separately, raise with ordinary culture medium standby, raising condition: temperature (25 ± 1) ℃, relative humidity 45%~65%.The standby fruit bat of getting 14 day age in the test is divided into 10 groups at random, give ordinary culture medium (blank group) respectively, contain 50% alcoholic acid solvent culture medium (solvent control group), by low (0.2%), in (1%), high (5%) dosage group in culture medium, add the present invention and positive control respectively and produce by CN200410035979 embodiment 1 and constitute basic, normal, high dosage group of the present invention and positive controls respectively.Every 24h record fruit bat death toll, every 4d changes a subculture, and is all dead until fruit bat, calculates indexs such as fruit bat average life, average maximum life span, half death time respectively.Experimental result shows that middle and high dosage group can prolong median lethal time, average life and the maximum life span of female male drosophila.Middle dosage can obviously prolong the average life of male fruit bat and the maximum life span of female male drosophila, and difference has significance P<0.01), see Table 4.
Table 4 the present invention is to the influence of drosophila survival experiment
Group | The fruit bat sex | The half death time (d) | Maximum life span (d) | Average life (d) |
Dosage group high dose group blank of the present invention group solvent control group among the low dose group the present invention of the present invention of blank group solvent control group positive controls | Robust robust female | 61 59 70 61 71 67 62 61 | 81.4±2.9. 82.4±5.2 89.5±7.2
** 84.8±4.9 90.3±3.4
** 86.9±3.2 80.3±4.7 80.7±7.8
| 61.5±15.4 59.0±14.7 69.9±15.8
** 61.0±14.9 70.9±18.2
** 66.9±15.1
** 62.1±10.5 60.8±17.3
|
Dosage group high dose group of the present invention among positive controls low dose group the present invention of the present invention | Female | 64 59 66 63 | 86.7±4.8
* 78.5±2.8 89.7±1.8
* 81.3±6.4
| 63.8±10.7
** 58.9±4.8 66.1±13.4
** 63.2±8.6
** |
Annotate:
*Expression is compared P<0.01 with the blank group;
*Expression is compared P<0.05 with the blank group
Following embodiment is further openly the present invention, need to prove that these embodiment only for optimal way of the present invention, do not limit the scope of protection of present invention.
The specific embodiment
Embodiment 1
15 parts of 15 parts of Pericarpium Citri Reticulataes of 10 parts of medicine fennels of 10 portions of Fructus Jujubaes of 10 portions of Ganodermas of 10 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
10 parts of 10 parts of Radix Clematidis of 10 portions of Radix Gentianae Macrophyllae of 10 parts of Radix Saposhnikoviaes of 15 parts of Rhizoma Chuanxiongs of 15 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
10 parts on 10 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 10 parts of Radix Achyranthis Bidentataes of 10 portions of Rhizoma Polygonati Odorati of 10 parts of Radix Peucedanis of 10 parts of Cortexs Eucommiae of Fructus Chaenomelis
10 parts of 10 portions of Rhizoma Et Radix Notopterygiis of 10 portions of Fructus Lyciis of 10 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Get each medical material in the compositions, processes is put in the airtight porcelain altar routinely, adds 20 times of amounts of Chinese liquor, airtight dipping 200 days, take out immersion, the squeezing medicinal residues, press liquor and immersion merge, and with an amount of stirring and dissolving of sucrose, add water and prepare in right amount, airtight, left standstill 1 day, filter, fill, promptly.
Embodiment 2
25 parts of 25 parts of Pericarpium Citri Reticulataes of 15 parts of medicine fennels of 15 portions of Fructus Jujubaes of 15 portions of Ganodermas of 5 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
15 parts of 15 parts of Radix Clematidis of 15 portions of Radix Gentianae Macrophyllae of 15 parts of Radix Saposhnikoviaes of 25 parts of Rhizoma Chuanxiongs of 25 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
15 parts on 15 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 15 parts of Radix Achyranthis Bidentataes of 15 portions of Rhizoma Polygonati Odorati of 15 parts of Radix Peucedanis of 15 parts of Cortexs Eucommiae of Fructus Chaenomelis
15 parts of 15 portions of Rhizoma Et Radix Notopterygiis of 15 portions of Fructus Lyciis of 15 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Get each medical material in the compositions, processes is put in the airtight porcelain altar routinely, adds 4 times of amounts of Chinese liquor, airtight dipping 10 days, take out immersion, the squeezing medicinal residues, press liquor and immersion merge, and add the protein sugar stirring and dissolving, add water and prepare in right amount, airtight, left standstill 3 days, filter, fill, promptly.
Embodiment 3
25 parts of 25 parts of Pericarpium Citri Reticulataes of 15 parts of medicine fennels of 15 portions of Fructus Jujubaes of 5 portions of Ganodermas of 15 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
15 parts of 15 parts of Radix Clematidis of 15 portions of Radix Gentianae Macrophyllae of 15 parts of Radix Saposhnikoviaes of 25 parts of Rhizoma Chuanxiongs of 25 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
15 parts on 15 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 15 parts of Radix Achyranthis Bidentataes of 15 portions of Rhizoma Polygonati Odorati of 15 parts of Radix Peucedanis of 15 parts of Cortexs Eucommiae of Fructus Chaenomelis
15 parts of 15 portions of Rhizoma Et Radix Notopterygiis of 15 portions of Fructus Lyciis of 15 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Get each medical material in the compositions, processes is put in the airtight porcelain altar routinely, adds 10 times of amounts of Chinese liquor, airtight dipping 100 days, take out immersion, the squeezing medicinal residues, press liquor and immersion merge, and the sweet an amount of stirring and dissolving of Jia Asiba adds water and prepares in right amount, airtight, left standstill 7 days, filter, fill, promptly.
Embodiment 4
25 parts of 25 parts of Pericarpium Citri Reticulataes of 15 parts of medicine fennels of 5 portions of Fructus Jujubaes of 15 portions of Ganodermas of 15 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
15 parts of 15 parts of Radix Clematidis of 15 portions of Radix Gentianae Macrophyllae of 15 parts of Radix Saposhnikoviaes of 25 parts of Rhizoma Chuanxiongs of 25 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
15 parts on 15 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 15 parts of Radix Achyranthis Bidentataes of 15 portions of Rhizoma Polygonati Odorati of 15 parts of Radix Peucedanis of 15 parts of Cortexs Eucommiae of Fructus Chaenomelis
15 parts of 15 portions of Rhizoma Et Radix Notopterygiis of 15 portions of Fructus Lyciis of 15 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Get each medical material in the compositions, processes is put in the airtight porcelain altar routinely, adds 15 times of amounts of Chinese liquor, airtight dipping 50 days, take out immersion, the squeezing medicinal residues, press liquor and immersion merge, and add an amount of stirring and dissolving of acesulfame potassium, add water and prepare in right amount, airtight, left standstill 5 days, filter, fill, promptly.
Embodiment 5
25 parts of 25 parts of Pericarpium Citri Reticulataes of 5 parts of medicine fennels of 15 portions of Fructus Jujubaes of 15 portions of Ganodermas of 15 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
15 parts of 15 parts of Radix Clematidis of 15 portions of Radix Gentianae Macrophyllae of 15 parts of Radix Saposhnikoviaes of 25 parts of Rhizoma Chuanxiongs of 25 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
15 parts on 15 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 15 parts of Radix Achyranthis Bidentataes of 15 portions of Rhizoma Polygonati Odorati of 15 parts of Radix Peucedanis of 15 parts of Cortexs Eucommiae of Fructus Chaenomelis
15 parts of 15 portions of Rhizoma Et Radix Notopterygiis of 15 portions of Fructus Lyciis of 15 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Get each medical material in the compositions, processes is put in the closed stainless steel jar routinely, adds 4 times of amounts of wine base, airtight dipping 10 days, take out immersion, the squeezing medicinal residues, press liquor and immersion merge, and with an amount of stirring and dissolving of sucrose, add water and prepare in right amount, airtight, left standstill 9 days, filter, fill, promptly.
Embodiment 6
25 parts of 8 parts of Pericarpium Citri Reticulataes of 15 parts of medicine fennels of 15 portions of Fructus Jujubaes of 15 portions of Ganodermas of 15 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
15 parts of 15 parts of Radix Clematidis of 15 portions of Radix Gentianae Macrophyllae of 15 parts of Radix Saposhnikoviaes of 25 parts of Rhizoma Chuanxiongs of 25 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
15 parts on 15 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 15 parts of Radix Achyranthis Bidentataes of 15 portions of Rhizoma Polygonati Odorati of 15 parts of Radix Peucedanis of 15 parts of Cortexs Eucommiae of Fructus Chaenomelis
15 parts of 15 portions of Rhizoma Et Radix Notopterygiis of 15 portions of Fructus Lyciis of 15 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Get each medical material in the compositions, processes is put in the closed stainless steel jar routinely, adds 20 times of amounts of wine base, airtight dipping 200 days, take out immersion, the squeezing medicinal residues, press liquor and immersion merge, and add an amount of stirring and dissolving of stevioside, add water and prepare in right amount, airtight, left standstill 2 days, filter, fill, promptly.
Embodiment 7
8 parts of 25 parts of Pericarpium Citri Reticulataes of 15 parts of medicine fennels of 15 portions of Fructus Jujubaes of 15 portions of Ganodermas of 15 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
15 parts of 15 parts of Radix Clematidis of 15 portions of Radix Gentianae Macrophyllae of 15 parts of Radix Saposhnikoviaes of 25 parts of Rhizoma Chuanxiongs of 25 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
15 parts on 15 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 15 parts of Radix Achyranthis Bidentataes of 15 portions of Rhizoma Polygonati Odorati of 15 parts of Radix Peucedanis of 15 parts of Cortexs Eucommiae of Fructus Chaenomelis
15 parts of 15 portions of Rhizoma Et Radix Notopterygiis of 15 portions of Fructus Lyciis of 15 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Get each medical material in the compositions, processes is put in the closed stainless steel jar routinely, adds 10 times of amounts of wine base, airtight dipping 100 days, take out immersion, the squeezing medicinal residues, press liquor and immersion merge, and with an amount of stirring and dissolving of sucrose, add water and prepare in right amount, airtight, left standstill 4 days, filter, fill, promptly.
Embodiment 8
25 parts of 25 parts of Pericarpium Citri Reticulataes of 15 parts of medicine fennels of 15 portions of Fructus Jujubaes of 15 portions of Ganodermas of 15 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
15 parts of 15 parts of Radix Clematidis of 15 portions of Radix Gentianae Macrophyllae of 15 parts of Radix Saposhnikoviaes of 25 parts of Rhizoma Chuanxiongs of 8 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
15 parts on 15 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 15 parts of Radix Achyranthis Bidentataes of 15 portions of Rhizoma Polygonati Odorati of 15 parts of Radix Peucedanis of 15 parts of Cortexs Eucommiae of Fructus Chaenomelis
15 parts of 15 portions of Rhizoma Et Radix Notopterygiis of 15 portions of Fructus Lyciis of 15 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Get each medical material in the compositions, processes is put in the closed stainless steel jar routinely, add Chinese liquor or 20 times of amounts of wine base, airtight dipping 90 days takes out immersion, the squeezing medicinal residues, press liquor and immersion merge, with sucrose or sweeting agent stirring and dissolving, adding water prepares in right amount, airtight, left standstill 6 days, filter, fill, promptly.
Embodiment 9
25 parts of 25 parts of Pericarpium Citri Reticulataes of 15 parts of medicine fennels of 15 portions of Fructus Jujubaes of 15 portions of Ganodermas of 15 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
15 parts of 15 parts of Radix Clematidis of 15 portions of Radix Gentianae Macrophyllae of 15 parts of Radix Saposhnikoviaes of 8 parts of Rhizoma Chuanxiongs of 25 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
15 parts on 15 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 15 parts of Radix Achyranthis Bidentataes of 15 portions of Rhizoma Polygonati Odorati of 15 parts of Radix Peucedanis of 15 parts of Cortexs Eucommiae of Fructus Chaenomelis
15 parts of 15 portions of Rhizoma Et Radix Notopterygiis of 15 portions of Fructus Lyciis of 15 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Get each medical material in the Chinese medicine composition, processes is concocted routinely, puts in the close container that lid arranged, add 15 times of amounts of wine base, heating is after treating that wine is little and boiling, soaked 80, and took out immersion, the squeezing medicinal residues, press liquor and immersion merge, and with an amount of stirring and dissolving of sucrose, add water and prepare in right amount, airtight, left standstill 8 days, filter, fill, promptly.
Embodiment 10
25 parts of 25 parts of Pericarpium Citri Reticulataes of 15 parts of medicine fennels of 15 portions of Fructus Jujubaes of 15 portions of Ganodermas of 15 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
15 parts of 15 parts of Radix Clematidis of 15 portions of Radix Gentianae Macrophyllae of 5 parts of Radix Saposhnikoviaes of 25 parts of Rhizoma Chuanxiongs of 25 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
15 parts on 15 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 15 parts of Radix Achyranthis Bidentataes of 15 portions of Rhizoma Polygonati Odorati of 15 parts of Radix Peucedanis of 15 parts of Cortexs Eucommiae of Fructus Chaenomelis
15 parts of 15 portions of Rhizoma Et Radix Notopterygiis of 15 portions of Fructus Lyciis of 15 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Get each medical material in the Chinese medicine composition, processes is concocted routinely, puts in the close container that lid arranged, add 10 times of amounts of wine base, heating is after treating that wine is little and boiling, soaked 70, and took out immersion, the squeezing medicinal residues, press liquor and immersion merge, and with an amount of stirring and dissolving of sucrose, add water and prepare in right amount, airtight, left standstill 8 days, filter, fill, promptly.
Embodiment 11
25 parts of 25 parts of Pericarpium Citri Reticulataes of 15 parts of medicine fennels of 15 portions of Fructus Jujubaes of 15 portions of Ganodermas of 15 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
15 parts of 15 parts of Radix Clematidis of 5 portions of Radix Gentianae Macrophyllae of 15 parts of Radix Saposhnikoviaes of 25 parts of Rhizoma Chuanxiongs of 25 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
15 parts on 15 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 15 parts of Radix Achyranthis Bidentataes of 15 portions of Rhizoma Polygonati Odorati of 15 parts of Radix Peucedanis of 15 parts of Cortexs Eucommiae of Fructus Chaenomelis
15 parts of 15 portions of Rhizoma Et Radix Notopterygiis of 15 portions of Fructus Lyciis of 15 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Get each medical material in the Chinese medicine composition, processes is concocted routinely, puts in the close container that lid arranged, add 6 times of amounts of wine base, heating is after treating that wine is little and boiling, soaked 60, and took out immersion, the squeezing medicinal residues, press liquor and immersion merge, and with an amount of stirring and dissolving of sucrose, add water and prepare in right amount, airtight, left standstill 3 days, filter, fill, promptly.
Embodiment 12
25 parts of 25 parts of Pericarpium Citri Reticulataes of 15 parts of medicine fennels of 15 portions of Fructus Jujubaes of 15 portions of Ganodermas of 15 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
15 parts of 5 parts of Radix Clematidis of 15 portions of Radix Gentianae Macrophyllae of 15 parts of Radix Saposhnikoviaes of 25 parts of Rhizoma Chuanxiongs of 25 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
15 parts on 15 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 15 parts of Radix Achyranthis Bidentataes of 15 portions of Rhizoma Polygonati Odorati of 15 parts of Radix Peucedanis of 15 parts of Cortexs Eucommiae of Fructus Chaenomelis
15 parts of 15 portions of Rhizoma Et Radix Notopterygiis of 15 portions of Fructus Lyciis of 15 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Get each medical material in the Chinese medicine composition, processes is concocted routinely, puts in the close container that lid arranged, add 4 times of amounts of wine base, heating is after treating that wine is little and boiling, soaked 50, and took out immersion, the squeezing medicinal residues, press liquor and immersion merge, and with an amount of stirring and dissolving of sucrose, add water and prepare in right amount, airtight, left standstill 2 days, filter, fill, promptly.
Embodiment 13
25 parts of 25 parts of Pericarpium Citri Reticulataes of 15 parts of medicine fennels of 15 portions of Fructus Jujubaes of 15 portions of Ganodermas of 15 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
5 parts of 15 parts of Radix Clematidis of 15 portions of Radix Gentianae Macrophyllae of 15 parts of Radix Saposhnikoviaes of 25 parts of Rhizoma Chuanxiongs of 25 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
15 parts on 15 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 15 parts of Radix Achyranthis Bidentataes of 15 portions of Rhizoma Polygonati Odorati of 15 parts of Radix Peucedanis of 15 parts of Cortexs Eucommiae of Fructus Chaenomelis
15 parts of 15 portions of Rhizoma Et Radix Notopterygiis of 15 portions of Fructus Lyciis of 15 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Get each medical material in the Chinese medicine composition, processes is concocted routinely, puts in the close container that lid arranged, add 15 times of amounts of wine base, soaked percolation 50, the liquid of filtering is soaked in collection, the squeezing medicinal residues, press liquor with soak the liquid of filtering and merge, with an amount of stirring and dissolving of sucrose, add water and prepare in right amount, airtight, left standstill 2 days, filter, fill, promptly.
Embodiment 14
40 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 2 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Above medicine adds 5 times of water, soaks 0.5 hour, decocts 1 hour, filters, and adds 5 times of water of water again, decocts 1 hour; Merge decoction liquor, filter, be evaporated to medical material: water is about 1: 1, transfers alcohol to 40%, and Cryoprecipitation 48 hours filters, and concentrating under reduced pressure becomes extractum, adds dextrin, Icing Sugar system granule, drying, and the system granule, packing promptly gets granule.
Embodiment 15
40 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 2 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Above medicine is added 10 times of water, soaked 3 hours, decocted again 1 hour; Merge decoction liquor, filter, be evaporated to medical material: water is about 2: 1, transfers alcohol to 85%, and Cryoprecipitation 12 hours filters, and concentrating under reduced pressure becomes extract dry, adds an amount of dextrin, Icing Sugar system soft material, and granulator is granulated, drying, and packing promptly gets granule.
Embodiment 16
40 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 2 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Above medicine is added 8 times of water, soaked 1 hour, decocted 3 hours, filter, medicinal residues add 10 times of water of water again, decoct 2 hours; Merge decoction liquor, filter, be evaporated to every milliliter and contain medical material 3g, add ethanol to containing alcohol 50%, Cryoprecipitation 48 hours filters, and concentrating under reduced pressure becomes extractum, and drying adds the Colla Corii Asini powder and adds appropriate amount of starch system granule, and the fill capsule promptly gets capsule.
Embodiment 17
40 parts of 40 parts of Pericarpium Citri Reticulataes of 2 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Above medicine is added 6 times of water, soaked 2 hours, decocted 2 hours, filter, medicinal residues add 8 times of water of water again, decoct 2 hours; Merge decoction liquor, filter, be evaporated to every milliliter and contain medical material 1g, add ethanol to containing alcohol 60%, Cryoprecipitation 48 hours filters, and concentrating under reduced pressure becomes extractum, drying, and adding Icing Sugar, starch are made granule in right amount, and tabletting promptly gets tablet.
Embodiment 18
40 parts of 4 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Above medicine is added 8 times of water, soaked 1 hour, decocted 1.5 hours, filter, medicinal residues add 8 times of water of water again, decoct 2 hours, filter, and medicinal residues add 8 times of water of water again, decocted 2 hours, and filtered, merge decoction liquor, filter, be evaporated to every milliliter and contain medical material 1.5g, add ethanol to containing alcohol 70%, Cryoprecipitation 24 hours, filter, concentrating under reduced pressure becomes extractum, drying, add appropriate amount of starch, the general ball of making promptly gets pill.
Embodiment 19
4 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Above medicine is added 10 times of water, soaked 1.5 hours, decocted 2 hours, filter, medicinal residues add 8 times of water of water again, decoct 1.5 hours, filter, and medicinal residues add 8 times of water of water again, decocted 1 hour, and filtered, merge decoction liquor, filter, be evaporated to every milliliter and contain medical material 2g, add ethanol to containing alcohol 70%, Cryoprecipitation 24 hours, filter, concentrating under reduced pressure becomes extractum, drying, mixing sieves, and promptly gets powder.
Embodiment 20
40 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 4 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
With above medicine crushing screening, it is an amount of to add binding agent Mel, and pill promptly gets pill.
Embodiment 21
40 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 4 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Above medicine is added 5 times of water, soaked 1.5 hours, decocted 3 hours, filter, medicinal residues add 10 times of water of water again, decoct 2 hours, filter, and medicinal residues add 8 times of water of water again, decocted 1.5 hours, and filtered, medicinal residues add 8 times of water of water again, decoct 1.5 hours, filter, merge decoction liquor, be evaporated to every milliliter and contain medical material 2.5g, add ethanol to containing alcohol 55%, Cryoprecipitation 48 hours filters, and concentrating under reduced pressure becomes extractum to go into the ethanol of normal concentration, stir, filter, promptly get tincture.
Embodiment 22
40 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 2 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Above medicine is added 10 times of water, soaked 0.5 hour, decocted 2.5 hours, filter, medicinal residues add 10 times of water of water again, decoct 2 hours, filter, medicinal residues add 8 times of water of water again, decoct 1.5 hours, filter, merge decoction liquor, filter, be evaporated to every milliliter and contain medical material 2g, add ethanol to containing alcohol 60%, Cryoprecipitation 24 hours, filter, concentrating under reduced pressure becomes extractum, and it is an amount of to add water, filter, other gets sucrose and adds an amount of heated and boiled of water, dissolving, filter, concentrate and make syrup, with above-mentioned concentrated solution mixing, boil, put coldly, add antiseptic and essence, thin up promptly gets syrup.
Embodiment 23
40 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 2 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Above medicine is added 6 times of water, soaked 0.5 hour, decocted 1 hour, filter, medicinal residues add 10 times of water of water again, decoct 1 hour, filter, and medicinal residues add 8 times of water of water again, decocted 0.5 hour, and filtered, merge decoction liquor, filter, be evaporated to every milliliter and contain medical material 1.5g, add ethanol to containing alcohol 50%, Cryoprecipitation 48 hours filters, concentrating under reduced pressure becomes extractum, and it is an amount of to add water, filters, and adds water to full dose, filter, fill, sterilization promptly gets mixture.
Embodiment 24
40 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 2 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Above medicine is added 6 times of water, soaked 0.5 hour, decocted 1 hour, filter; medicinal residues add 10 times of water of water again, decoct 1 hour, filter, and medicinal residues add 8 times of water of water again; decocted 0.5 hour, and filtered, merge decoction liquor, filter; be evaporated to every milliliter and contain medical material 1.5g, add ethanol to containing alcohol 50%, Cryoprecipitation 48 hours; filter, concentrating under reduced pressure becomes extractum, drying and crushing; add an amount of dextrin, magnesium stearate, stevioside, mixing, with dry granulation mechanism grain, promptly.
Embodiment 25
40 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
2 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Above medicine is added 6 times of water, soaked 0.5 hour, decocted 1 hour, filter, medicinal residues add 10 times of water of water again, decoct 1 hour, filter, medicinal residues add 8 times of water of water again, decoct 0.5 hour, filter, merge decoction liquor, filter, be evaporated to every milliliter and contain medical material 1.5g, add ethanol to containing alcohol 50%, Cryoprecipitation 48 hours, filter, concentrating under reduced pressure becomes extractum, and it is an amount of to add water, filter, other gets sucrose and adds an amount of heated and boiled of water, dissolving, filter, concentrate and make syrup, with above-mentioned concentrated solution mixing, boil, put coldly, add antiseptic and essence, thin up promptly gets syrup.
Embodiment 26
40 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 2 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Above medicine is added 4 times of water, soaked 0.5 hour, add water to 10 times of water, decocted 2 hours, filter, medicinal residues add 8 times of water of water again, decoct 1.5 hours, filter, merge decoction liquor, filter, be evaporated to every milliliter and contain medical material 2g, add ethanol to containing alcohol 50%, Cryoprecipitation 12 hours filters, and concentrating under reduced pressure becomes extractum, drying, with Icing Sugar, the system granule, drying, packing promptly gets granule.
Embodiment 27
40 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 2 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Above medicine adds 4 times of water, soaks 0.5 hour, adds water to 8 times of water, decocts 2.5 hours, filter, medicinal residues add 6 times of water of water again, decoct 2 hours, filter, merge decoction liquor, filter, be evaporated to every milliliter and contain medical material 1g, add ethanol to containing alcohol 60%, Cryoprecipitation 24 hours filters, concentrating under reduced pressure becomes extractum, and drying adds lactose, the sweet mixing of A Siba, dry granulation, packing promptly gets granule.
Embodiment 28
40 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 2 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Above medicine adds 5 times of water, soaks 0.5 hour, adds water to 10 times of water, decocts 3 hours, filter, medicinal residues add 8 times of water of water again, decoct 2 hours, filter, merge decoction liquor, filter, be evaporated to every milliliter and contain medical material 3g, add ethanol to containing alcohol 45%, Cryoprecipitation 24 hours filters, concentrating under reduced pressure becomes extractum, and drying adds the starch mixing, dry granulation, encapsulated, promptly get capsule.
Embodiment 29
40 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 2 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Above medicine is with 60% alcohol reflux 2 times, and each 1 hour, merge alcohol reflux liquid, decompression recycling ethanol also concentrates; Medicinal residues add 5 times of water gagings again and decoct 2 times, decoct 2 hours at every turn, merge decoction liquor, concentrate, and medicinal liquid adds ethanol when being cooled to room temperature slightly, make to contain the alcohol amount and reach 60%, and cold preservation 24 hours filters, and decompression filtrate recycling ethanol concentrates drying; Fine powder adds an amount of dextrin, Icing Sugar system soft material, and granulator is granulated, drying, and quality inspection, packing promptly get granule.
Embodiment 30
40 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 2 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Above medicine is with 65% alcohol reflux 3 times, and each 1 hour, merge alcohol reflux liquid, decompression recycling ethanol also concentrates drying; Medicinal residues add 8 times of water gagings again and decoct 2 times, decoct 0.5 hour at every turn, merge decoction liquor, concentrate, and medicinal liquid adds ethanol when being cooled to room temperature slightly, make to contain the alcohol amount and reach 70%, and cold preservation 24 hours filters, and decompression filtrate recycling ethanol concentrates drying; Get alcohol extraction dry powder and water and promote the powder mixing, add right amount of auxiliary materials system granule, tabletting, the enteric coated enteric coated tablet that promptly gets.
Embodiment 31
40 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
2 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Above medicine is with 50% reflux, extract, 3 times, and each 1.5 hours, merge alcohol reflux liquid, decompression recycling ethanol also concentrates; Medicinal residues add 6 times of water gagings again and decoct 52 times, decoct 0.5 hour at every turn, merge decoction liquor, concentrate, medicinal liquid adds ethanol when being cooled to room temperature slightly, makes to contain the alcohol amount and reach 70%, cold preservation 24 hours filters decompression filtrate recycling ethanol, concentrate and the alcohol-extracted extract merging, it is an amount of to add water, filters, filtrate adds the ethanol of normal concentration, stir, filter, promptly get tincture.
Embodiment 32
40 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 2 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Above medicine is with 70% alcohol reflux 3 times, and each 2.5 hours, merge alcohol reflux liquid, decompression recycling ethanol also concentrates, and drying is pulverized, and adds appropriate amount of starch, and the general ball of making promptly gets pill.
Embodiment 33
40 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 2 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Above medicine is with 80% alcohol reflux 2 times, and each 0.5 hour, merge alcohol reflux liquid, decompression recycling ethanol also concentrates; Medicinal residues add 5 times of water gagings again and decoct 1 time, decoct 3 hours at every turn, merge decoction liquor, concentrate, and medicinal liquid adds ethanol when being cooled to room temperature slightly, make to contain the alcohol amount and reach 40%, and cold preservation 24 hours filters, and decompression filtrate recycling ethanol concentrates; Get alcohol-extracted extract and mix with the water extracted immersing paste, other gets sucrose and adds an amount of heated and boiled of water, and dissolving is filtered, and concentrates and makes syrup, with above-mentioned concentrated solution mixing, boils, and puts coldly, adds antiseptic and essence, and thin up promptly gets syrup.
Embodiment 34
40 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
30 parts of 2 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Get above pulverizing medicinal materials, sieve, add appropriate amount of starch, the general ball of making promptly gets pill.
Embodiment 35
40 parts of 40 parts of Pericarpium Citri Reticulataes of 30 parts of medicine fennels of 30 portions of Fructus Jujubaes of 30 portions of Ganodermas of 30 parts of Semen Ziziphi Spinosaes of Radix Adenophorae (Radix Glehniae)
30 parts of 30 parts of Radix Clematidis of 30 portions of Radix Gentianae Macrophyllae of 30 parts of Radix Saposhnikoviaes of 40 parts of Rhizoma Chuanxiongs of 40 portions of Radix Paeoniae Albas of Radix Rehmanniae Preparata
30 parts on 30 parts of Cortex cinnamomi japonici (Ramulus Cinnamomi)s of 30 parts of Radix Achyranthis Bidentataes of 30 portions of Rhizoma Polygonati Odorati of 30 parts of Radix Peucedanis of 30 parts of Cortexs Eucommiae of Fructus Chaenomelis
2 parts of 30 portions of Rhizoma Et Radix Notopterygiis of 30 portions of Fructus Lyciis of 30 portions of Radix Glycyrrhizaes of Massa Medicata Fermentata
Get above medical material with 85% alcohol reflux 3 times, each 1.5 hours, merge alcohol reflux liquid, decompression recycling ethanol also concentrates; Medicinal residues add 7 times of water gagings again and decoct 2 times, decoct 2.5 hours at every turn, merge decoction liquor, concentrate, medicinal liquid adds ethanol when being cooled to room temperature slightly, makes to contain alcohol amount and reach 55%, and cold preservation 24 hours filters, decompression filtrate recycling ethanol concentrates, and gets alcohol-extracted extract and the water extracted immersing paste mixing and water adding is an amount of, precipitation is filtered, and other gets sucrose and makes syrup, merge with above-mentioned medicinal liquid, add water system full dose, filter, fill, sterilization promptly gets mixture.