CN1857410A - Chinese medicine for treating neuorsis and its preparing method - Google Patents
Chinese medicine for treating neuorsis and its preparing method Download PDFInfo
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- CN1857410A CN1857410A CN 200610046033 CN200610046033A CN1857410A CN 1857410 A CN1857410 A CN 1857410A CN 200610046033 CN200610046033 CN 200610046033 CN 200610046033 A CN200610046033 A CN 200610046033A CN 1857410 A CN1857410 A CN 1857410A
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Abstract
The present invention relates to neurosis treating Chinese medicine and its preparation process. The medicine is prepared with four kinds of Chinese medicinal materials, including total ginseng stem and leaf saponin, Tenghehuan, schisandra and glossy ganoderma and supplementary material. The preparation process includes grinding schisandra into meal, twice alcohol solution reflux, filterng and concentrating to obtain extractum; twice decoction Tenghehuan and glossy ganoderma, filterng and concentrating to obtain extractum; merging extractum, drying and crushing into fine powder; adding total ginseng stem and leaf saponin and supplementary material, pelletizing, encapsulating or bagging to obtain the medicine. The medicine may be prepared into various preparation form, and has accurate dosage, fast acting and other advantages. It has the functions of invigorating Qi, promoting secretion and tranquilizing.
Description
(1) technical field
The present invention relates to Chinese patent medicine, particularly relate to a kind ofly treat cardiopalmus, be insomnia, the Chinese medicine and the preparation method of neurasthenia such as forgetful.
(2) background technology
Current, reach operating pressure with the quickening pace of modern life, suffer from patient neurasthenia and get more and more, this disease morbidity crowd mostly is cadre and workman.The cause of disease, pathology: cardiopalmus, be insomnia, the forgetful category that all belongs to modern neurasthenia.The cardiopalmus of the traditional Chinese medical science, be insomnia, though the pathogeny reason of strongly fragrant disease is many, but the three all has something in common, and just the primary symptom of clinical manifestation is different to some extent, therefore in clinical diagnosis had palpitation, be insomnia, forgetful not, it is main that the clinical observation pathomechanism belongs to the deficiency of both the heart and spleen type, and caused by hepatic stagnation qi stagnation takes second place.The pathogeny of deficiency of both the heart and spleen type is that overstrain is pondered over too, damage heart spleen is hindered in heart hematozemia then, and deficiency of both the heart and spleen then god is become homeless foster, hinder in then fortune imbalance of spleen, change source deficiency, nutrient blood thanks to is full of, then can not on grow in the heart, it is foster also to cause god to become homeless, so the performance dizziness and tinnitus, shortness of breath and palpitation etc. (symptom of blood deficiency), insomnia and dreamful sleep etc. (god become homeless foster symptom).Adopt the Yixinningshen Chinese medicine preparation of stem and leaf of Radix Ginseng total saponins, Fructus Schisandrae Chinensis, TENGHEHUAN, the preparation of Ganoderma Chinese medicine, but tonifying QI to produce body fluid, tranquilizing by nourishing the heart; Be used for shortness of breath and palpitation, dreaminess insomnia, neurasthenia's disease of hypomnesis.The Chinese medicine of the treatment neurasthenia that the our factory has produced, trade name are Yixinningshen, though this medicine to treatment cardiopalmus, be insomnia, neurasthenia such as forgetful has good curative effect, has only the single dosage form of tablet, can't adapt to the selection of patient to dosage form.
(3) summary of the invention
The objective of the invention is provides a kind of Chinese medicinal capsule agent and granule for the treatment of neurasthenia at the problems referred to above, further improves the quality of products and technology content, satisfies needs of patients.This Chinese medicinal capsule agent and granule name are called Yixinningshen.
The technical scheme that adopts is:
A kind of Chinese medicine for the treatment of neurasthenia, containing medicine components is stem and leaf of Radix Ginseng total saponins, TENGHEHUAN, Fructus Schisandrae Chinensis, Ganoderma, and its compatibility is stem and leaf of Radix Ginseng total saponins 10g, TENGHEHUAN 1000g, Fructus Schisandrae Chinensis 500g, Ganoderma 500g, and dosage form is capsule or granule.
A kind of preparation method for the treatment of the Chinese medicine (capsule) of neurasthenia, get stem and leaf of Radix Ginseng total saponins 10g, TENGHEHUAN 1000g, Fructus Schisandrae Chinensis 500g, Ganoderma 500g are standby, get Fructus Schisandrae Chinensis powder and be broken into coarse powder, add 75% ethanol warm macerating 30 minutes, the reflux, extract, secondary, 2.5 hours for the first time, 2 hours for the second time, merge extractive liquid, reclaimed ethanol, be concentrated into the thick paste shape, its relative density 1.34-1.37 (70-80 ℃ of survey).Get TENGHEHUAN and Ganoderma two flavors, decoct with water secondary, 2 hours for the first time, 1.5 hours for the second time, filter; Merging filtrate is concentrated into the thick paste shape, its relative density 1.34-1.37 (70-80 ℃ of survey).Get above-mentioned thick paste, merge, drying is ground into fine powder, adds stem and leaf of Radix Ginseng total saponins and starch 80-100g, mixing is made granule, drying, magnesium stearate or the Pulvis Talci of adding grain amount 0.5-1% behind the granulate, mixing incapsulates, and every capsules dress 0.3g makes 1000 altogether.
Above-mentioned every capsules also can be adorned 0.25g, makes 1200 altogether.
A kind of preparation method for the treatment of the Chinese medicine (granule) of neurasthenia, get stem and leaf of Radix Ginseng total saponins 10g, TENGHEHUAN 1000g, Fructus Schisandrae Chinensis 500g, Ganoderma 500g, cane sugar powder 2200g is standby, get Fructus Schisandrae Chinensis powder and be broken into coarse powder, add 75% ethanol warm macerating 30 minutes, the reflux, extract, secondary, 2.5 hours for the first time, 2 hours for the second time, merge extractive liquid, reclaimed ethanol, be concentrated into the thick paste shape, its relative density 1.34-1.37 (70-80 ℃ of survey).Get TENGHEHUAN and Ganoderma two flavors, decoct with water secondary, 2 hours for the first time, 1.5 hours for the second time, filter; Merging filtrate is concentrated into the thick paste shape, and its relative density 1.34-1.37 (70-80 ℃ of survey) merges with the preceding paragraph thick paste, and stem and leaf of Radix Ginseng total saponins is added mixing in the thick paste with 2-8ml ethanol or 10-25ml hot water (70-80 ℃) dissolving back.Get 1 part of thick paste and cane sugar powder 4.2-4.4 part mixing, make granule, drying is made granule 2400g altogether, is distributed into bag, every packed 12g.
Above-mentioned stem and leaf of Radix Ginseng total saponins also can directly add mixing in the cane sugar powder, gets 1 part of thick paste and above-mentioned cane sugar powder 4.2-4.4 part mixing again, makes granule, and drying is made granule 2400g altogether, is distributed into bag, every packed 12g.
Above-mentioned a kind of Chinese medicine (granule) for the treatment of neurasthenia also can be made into the granule of no sucrose, and its preparation method is got stem and leaf of Radix Ginseng total saponins 10g, TENGHEHUAN 1000g, Fructus Schisandrae Chinensis 500g, Ganoderma 500g, and adjuvant soluble starch 386g, steviosin 4g are standby.Get Fructus Schisandrae Chinensis powder and be broken into coarse powder, add 75% ethanol warm macerating 30 minutes, the reflux, extract, secondary, 2.5 hours for the first time, 2 hours for the second time, merge extractive liquid, reclaimed ethanol, is concentrated into the thick paste shape, its relative density 1.34-1.37 (70-80 ℃ of survey).Get TENGHEHUAN and Ganoderma two flavors, decoct with water secondary, 2 hours for the first time, 1.5 hours for the second time, filter; Merging filtrate is concentrated into the thick paste shape, and its relative density 1.34-1.37 (70-80 ℃ of survey) merges with the preceding paragraph thick paste, add stem and leaf of Radix Ginseng total saponins, soluble starch, steviosin, mixing is made granule, drying, make granule 600g altogether, be distributed into bag, every packed 3g.
Above-mentioned adjuvant also can be soluble starch 236g, dextrin 150g, steviosin 4g.
A kind of Chinese medicine for the treatment of neurasthenia of the present invention has increased dosage form, and the preparation reasonable mixture ratio has convenient drug administration, and is rapid-action, drug utilization degree height, and constant product quality is fit to the advantage that patient's selection is taken.Tonifying QI to produce body fluid, tranquilizing by nourishing the heart is a shortness of breath and palpitation, dreaminess insomnia, hypomnesis, the first-selected Chinese medicine of neurastheniac.
(4) specific embodiment
Embodiment one
A kind of preparation method for the treatment of the Chinese medicine (capsule) of neurasthenia, get stem and leaf of Radix Ginseng total saponins 10g, TENGHEHUAN 1000g, Fructus Schisandrae Chinensis 500g, Ganoderma 500g are standby, get Fructus Schisandrae Chinensis powder and be broken into coarse powder, add 75% ethanol warm macerating 30 minutes, the reflux, extract, secondary, 2.5 hours for the first time, 2 hours for the second time, merge extractive liquid, reclaimed ethanol, be concentrated into the thick paste shape, its relative density 1.35 (75 ℃ of surveys).Get TENGHEHUAN and Ganoderma two flavors, decoct with water secondary, 2 hours for the first time, 1.5 hours for the second time, filter; Merging filtrate is concentrated into the thick paste shape, its relative density 1.36 (80 ℃ of surveys).Get above-mentioned thick paste, merge, drying is ground into fine powder, adds stem and leaf of Radix Ginseng total saponins and starch 90g, mixing is made granule, drying, the magnesium stearate or the Pulvis Talci of adding grain amount 0.8% behind the granulate, mixing incapsulates, and every capsules dress 0.3g makes 1000 altogether.
Usage and consumption: oral, one time 5,3 times on the one.
Embodiment two
The capsular preparation method of Yixinningshen
Embodiment two is identical with embodiment one, and every capsules dress 0.25g makes 1200 altogether.
Usage and consumption: oral, one time 6,3 times on the one.
Embodiment three
A kind of preparation method for the treatment of the Chinese medicine (granule contains sugar) of neurasthenia, get stem and leaf of Radix Ginseng total saponins 10g, TENGHEHUAN 1000g, Fructus Schisandrae Chinensis 500g, Ganoderma 500g, cane sugar powder 2200g is standby, get Fructus Schisandrae Chinensis powder and be broken into coarse powder, add 75% ethanol warm macerating 30 minutes, the reflux, extract, secondary, 2.5 hours for the first time, 2 hours for the second time, merge extractive liquid, reclaimed ethanol, be concentrated into the thick paste shape, its relative density 1.35 (75 ℃ of surveys).Get TENGHEHUAN and Ganoderma two flavors, decoct with water secondary, 2 hours for the first time, 1.5 hours for the second time, filter; Merging filtrate is concentrated into the thick paste shape, and its relative density 1.36 (75 ℃ of surveys) merges with the preceding paragraph thick paste, and stem and leaf of Radix Ginseng total saponins is added mixing in the thick paste with 5ml ethanol or 18ml hot water (75 ℃) dissolving back.Get 1 part of thick paste and 4.3 parts of mixings of cane sugar powder, make granule, drying is made granule 2400g altogether, is distributed into bag, every packed 12g.
Usage and consumption: oral, a 12g, 3 times on the one.
Embodiment four
A kind of preparation method for the treatment of the Chinese medicine (granule contains sugar) of neurasthenia, embodiment four and embodiment three are basic identical, difference is that stem and leaf of Radix Ginseng total saponins is directly added mixing in the cane sugar powder, get 1 part of thick paste and 4.3 parts of mixings of above-mentioned cane sugar powder, make granule, drying is made granule 2400g altogether, be distributed into bag, every packed 12g.
Usage and consumption: oral, a 12g, 3 times on the one.
Embodiment five
A kind of preparation method for the treatment of the Chinese medicine (granule sugar-free) of neurasthenia is got stem and leaf of Radix Ginseng total saponins 10g, TENGHEHUAN 1000g, Fructus Schisandrae Chinensis 500g, Ganoderma 500g, adjuvant soluble starch 386g, steviosin 4g.Get Fructus Schisandrae Chinensis powder and be broken into coarse powder, add 75% ethanol warm macerating 30 minutes, the reflux, extract, secondary, 2.5 hours for the first time, 2 hours for the second time, merge extractive liquid, reclaimed ethanol, is concentrated into the thick paste shape, its relative density 1.35 (75 ℃ of surveys).Get TENGHEHUAN and Ganoderma two flavors, decoct with water secondary, 2 hours for the first time, 1.5 hours for the second time, filter; Merging filtrate is concentrated into the thick paste shape, and its relative density 1.36 (75 ℃ of surveys) is got above-mentioned thick paste and merged drying, be ground into fine powder, add stem and leaf of Radix Ginseng total saponins, soluble starch 386g, steviosin 4g, mixing is made granule, drying is made granule 600g altogether, is distributed into bag, every packed 3g.
Usage and consumption: oral, a 3g, 3 times on the one.
Embodiment six
A kind of preparation method for the treatment of the Chinese medicine (granule sugar-free) of neurasthenia, embodiment six and embodiment five are basic identical, and difference is that adjuvant is soluble starch 236g, dextrin 150g, steviosin 4g.Every packed 3g.
Usage and consumption: oral, a 3g, 3 times on the one.
Claims (7)
1, a kind of Chinese medicine for the treatment of neurasthenia, formulated by Chinese crude drug stem and leaf of Radix Ginseng total saponins 10g, TENGHEHUAN 1000g, Fructus Schisandrae Chinensis 500g, Ganoderma 500g and appropriate amount of auxiliary materials, it is characterized in that this medicine is capsule or granule.
2, a kind of preparation method of Chinese medicine for the treatment of neurasthenia according to claim 1, it is characterized in that getting stem and leaf of Radix Ginseng total saponins 10g, TENGHEHUAN 1000g, Fructus Schisandrae Chinensis 500g, Ganoderma 500g are standby, get Fructus Schisandrae Chinensis powder and be broken into coarse powder, add 75% ethanol warm macerating 30 minutes, the reflux, extract, secondary, 2.5 hours for the first time, 2 hours for the second time, merge extractive liquid,, reclaim ethanol, be concentrated into the thick paste shape, survey its relative density 1.34-1.37, get TENGHEHUAN and Ganoderma two flavors at 70-80 ℃, decoct with water secondary, 2 hours for the first time, 1.5 hours for the second time, filter; Merging filtrate is concentrated into the thick paste shape, surveys its relative density 1.34-1.37 at 70-80 ℃, get above-mentioned thick paste, merge drying, be ground into fine powder, add stem and leaf of Radix Ginseng total saponins and starch 80-100g, mixing, make granule, drying, magnesium stearate or the Pulvis Talci of adding grain amount 0.5-1% behind the granulate, mixing, incapsulate, every capsules dress 0.3g makes 1000 altogether.
3, a kind of preparation method of Chinese medicine for the treatment of neurasthenia according to claim 2 is characterized in that described every capsules also can adorn 0.25g, makes 1200 altogether.
4, a kind of preparation method of Chinese medicine for the treatment of neurasthenia according to claim 1, it is characterized in that getting stem and leaf of Radix Ginseng total saponins 10g, TENGHEHUAN 1000g, Fructus Schisandrae Chinensis 500g, Ganoderma 500g, cane sugar powder 2200g is standby, get Fructus Schisandrae Chinensis powder and be broken into coarse powder, add 75% ethanol warm macerating 30 minutes, the reflux, extract, secondary, 2.5 hours for the first time, 2 hours for the second time, merge extractive liquid,, reclaim ethanol, be concentrated into the thick paste shape, survey its relative density 1.34-1.37, get TENGHEHUAN and Ganoderma two flavors at 70-80 ℃, decoct with water secondary, 2 hours for the first time, 1.5 hours for the second time, filter; Merging filtrate, be concentrated into the thick paste shape, survey its relative density 1.34-1.37 at 70-80 ℃, merge, stem and leaf of Radix Ginseng total saponins is added mixing in the thick paste with the hot water 10-25ml dissolving back of 2-8ml ethanol or 70-80 ℃ with the preceding paragraph thick paste, get 1 part of thick paste and cane sugar powder 4.2-4.4 part mixing, make granule, drying is made granule 2400g altogether, be distributed into bag, every packed 12g.
5, a kind of preparation method of Chinese medicine for the treatment of neurasthenia according to claim 4, it is characterized in that described stem and leaf of Radix Ginseng total saponins also can directly add mixing in the cane sugar powder, get 1 part of thick paste and cane sugar powder 4.2-4.4 part mixing again, make granule, dry, make granule 2400g altogether, be distributed into bag, every packed 12g.
6, according to claim 1 or 4 described a kind of preparation method of Chinese medicine for the treatment of neurasthenia, it is characterized in that getting stem and leaf of Radix Ginseng total saponins 10g, TENGHEHUAN 1000g, Fructus Schisandrae Chinensis 500g, Ganoderma 500g, adjuvant soluble starch 386g, steviosin 4g is standby, get Fructus Schisandrae Chinensis powder and be broken into coarse powder, add 75% ethanol warm macerating 30 minutes, reflux, extract, secondary, 2.5 hours for the first time, 2 hours for the second time, merge extractive liquid, reclaims ethanol, is concentrated into the thick paste shape, survey its relative density 1.34-1.37 at 70-80 ℃, get TENGHEHUAN and Ganoderma two flavors, decoct with water secondary, 2 hours for the first time, 1.5 hours for the second time, filter; Merging filtrate is concentrated into the thick paste shape, surveys its relative density 1.34-1.37 at 70-80 ℃, merges with the preceding paragraph thick paste, add stem and leaf of Radix Ginseng total saponins, soluble starch, steviosin, mixing is made granule, drying, make granule 600g altogether, be distributed into bag, every packed 3g.
7, a kind of preparation method of Chinese medicine for the treatment of neurasthenia according to claim 6 is characterized in that described adjuvant also can be soluble starch 236g, dextrin 150g, steviosin 4g.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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| CN 200610046033 CN1857410A (en) | 2006-03-14 | 2006-03-14 | Chinese medicine for treating neuorsis and its preparing method |
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| CN 200610046033 CN1857410A (en) | 2006-03-14 | 2006-03-14 | Chinese medicine for treating neuorsis and its preparing method |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103039996A (en) * | 2012-12-28 | 2013-04-17 | 杨石 | Health food with function of improving sleep |
| CN106728289A (en) * | 2016-12-30 | 2017-05-31 | 辽宁上药好护士药业（集团）有限公司 | Application of the Yixinningshen tablet in treatment diplocardia medicine is prepared |
-
2006
- 2006-03-14 CN CN 200610046033 patent/CN1857410A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103039996A (en) * | 2012-12-28 | 2013-04-17 | 杨石 | Health food with function of improving sleep |
| CN106728289A (en) * | 2016-12-30 | 2017-05-31 | 辽宁上药好护士药业（集团）有限公司 | Application of the Yixinningshen tablet in treatment diplocardia medicine is prepared |
| CN106728289B (en) * | 2016-12-30 | 2020-04-14 | 辽宁上药好护士药业（集团）有限公司 | Application of heart-benefiting mind-tranquilizing tablet in preparation of medicine for treating diplocardia |
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Open date: 20061108 |