CN1824219A - Medicine and food dual purpose Chinese medicine for preventing and treating impotence and seminal emission and its manufacturing method - Google Patents

Medicine and food dual purpose Chinese medicine for preventing and treating impotence and seminal emission and its manufacturing method Download PDF

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CN1824219A
CN1824219A CNA2005101364275A CN200510136427A CN1824219A CN 1824219 A CN1824219 A CN 1824219A CN A2005101364275 A CNA2005101364275 A CN A2005101364275A CN 200510136427 A CN200510136427 A CN 200510136427A CN 1824219 A CN1824219 A CN 1824219A
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颜怀伟
颜怀玮
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Abstract

A Chinese medicine used as both medicine and food for preventing and treating impotence and emission by Chinese medicine is prepared from 9 Chinese-medicinal materials including oyster shell, cinnamon bark, yam, wolfberry fruit, etc. Its preparing process is also disclosed.

Description

Control impotence and seminal emission medicinal and edible Chinese medicine and manufacture method
Sexual impotence is meant male genitals's penile erectile function obstacle, mainly show to have suddenly and not and rise, rise and not hard, hard and do not endure, very and soon, in other words be exactly that the male penis anorthosis carries out or continues strong to finishing sexual behaviour, all belong to the sexual impotence category, though it is a lot of to cause the factor of sexual impotence, as smoking be generally acknowledge cause one of main factor of sexual impotence, Australia and Canada in addition straight from the shoulder this information is imprinted on the cigarette case, the medicine of obesity and heart disease and some treatments thereof etc. also is some reasons that cause sexual impotence, even sexual impotence itself just may be the omen of heart disease and other disease, but majority all is a psychology and constitutive, no matter which kind of sexual impotence all is difficult to finish sexual intercourse, cause the unusual and female mental variation of male's sexual excitation, the unavoidable goodwill as between spouses that influences, even fertility relates to legal issue etc., the male of application form express contract 30% has sexual impotence in various degree, and practical situation is more serious than survey data, because investigation shows equally: have only 1 to be ready to seek medical advice in 10 impotent patients, in a single day the male suffers from sexual impotence, the most direct reaction is to negate its existence, be absorbed in anxiety and uneasy emotion, and escape and companion have any intimate behavior, get off for a long time harm two people's relation, even cause broken marriages, even if the most conservative measuring and calculating whole world at least also has 100,000,000 male about 40 to 70 years old influenced by sexual impotence at present, and have obviously and the rejuvenation trend of phenomenal growth speed and amplitude: the incidence rate of sexual impotence increases along with age level, middle age mainly is (to treat diabetes because of medicine to the old people, heart disease etc.) side effect and cause sexual impotence, youngster also have because of performance to be desired, too nervous and form sexual impotence.
The traditional Chinese medical science claims seminal emission or consumption of essence with seminal fluid self discard phenomenon.Dream is arranged and something lost person by name " nocturnal emission ", no dream and losing, even when clear-headed seminal fluid not skid off the person voluntarily be " spermatorrhea ".How by suffer from a deficiency of the kidney smart close solid, or the heart, renal function deficiency, or due to the damp invasion of lower energizer.Doctor trained in Western medicine is found in phimosis, redundant prepuce, urethritis, prostate diseases etc.The initial phase that dream is arranged and lose the spermatorrhea of regaining consciousness often, nocturnal emission, spermatorrhea are two kinds of different diseases of seminal emission weight, do not have essential distinction.Modern medicine thinks that when human body was weaker, unsound state will appear in central nervous system's function, and sexual function also can get muddled, and seminal emission or sexual impotence etc. take place easily.Motherland's medical science thinks that human body is an organic whole, though Each performs its own functions for the vital organs of the human body, they are mutual coordination, complementary on function, also is interactional on pathology.The generation of man semen, operation are relevant with vitals such as the heart, liver, kidneys, if these internal organs are ill or function is not quite desirable, mutual relation will be lacked of proper care, and will inevitably make to have bad physiques, and may bring out seminal emission.At this moment, overwork, factors such as malnutrition, congenital defect, tired mind all can cause the heart, liver, renal function imbalance, cause physical morbid state, thereby bring out seminal emission.Though seminal emission is meant not the disease of releasing voluntarily because of the sexual intercourse seminal fluid and physiological is arranged with pathologic different, but the seminal emission with " epiphora " though different all be to lose the excretory phenomenon of seminal fluid under the automatic control state, but overflow is that seminal fluid accumulates and too much causes seminal emission, belong to the physiological phenomenon, give no cause for anxiety, sexual behaviour is not being met and passes out semen and also can regard epiphora as sometimes.Treatment medical science seminal emission refers generally to the pathologic seminal emission, and smartly closes factors such as not solid or damp and hot, phlegm-fire to cause smart chamber disturbed relevant with suffering from a deficiency of the kidney.One is physiological phenomenon, and one is pathological manifestations.Treat also different with the method for handling.The physiological seminal emission is meant unmarried youth or separation after marriage, the ejaculation of nonaccess.General 2 weeks or longer time pass out semen 1 time, do not cause the health any discomfort, and penile erectile function is normal, can not have dream and loses, and also can dream be arranged and lose.Pathologic seminal emission more complicated, all multi-pathogenesis all can cause, commonly encountered diseases is not hidden because of having instability of kidney QI, deficiency of kidney-essence to cause to suffer from a deficiency of the kidney.The cause of disease can by work with one's mind excessively, vain hope is unsuccessful causes that fire is high partially mutually.Eating and drinking without temperance, pure wine savoury, long-pending humidogene heat, damp invasion of lower energizer also is the important origin cause of formation.
No matter modern society is that development in science and technology or phychology, speed are primary demands, this originally gives no cause for much criticism for the pressure that the growth requirement and the people of society face, but it then is improper that sexual life is applied mechanically also that it makes short work of, and the prerequisite of fine sexual life is that the impression that harmonious emotion is arranged, pay attention to the companion is only the first step of keeping happy sexual life; The present invention be exactly with that in mind, according to traditional Chinese medical science globality pathology Design Theory, all be because due to the body constitution and a high essence and the intercommunity difficult problem of the degree of association each other with better solution sexual impotence, seminal emission, detailed following:
Chinese medicine and western modern medicine disease preventing and treating theory one significantly difference be that the former does not rest on analysis to the concrete cause of disease to pathological knowledge, show the nonantagonistic latter and then be antagonism, that is the former emphasizes is human body integral and the ability that how improves the antagonism disease from integral body, the latter then is that " sitting in the right seat " is as what microorganism, malnutrition or surplus, poisonous and harmful substance (comprising medicine) and effect etc. cause any disease, though theoretic dispute is very big, even opposition and antagonism, whom shows under a lot of situations whom does not persuade, mutual contradiction or do not have public opinion even, undisputable fact really but they can both be cured the disease and/or reach a cure, this also proved human to medicine especially in, cognitive level and ability between western modern medicine is mutual are also very limited, and arbitrarily in the dogmatize about, the western modern medicine theory who to whose mistake, can not declare that more which is right and which is wrong, because both sides do not have enough conclusive evidences to prove that the other side is wrong, so do not meet the view of science, so should advocate the pardon scientific research of promptly taking facts as the basis and deepen continuously progressively gets and improves relevant theoretical dispute clear with practice and argue, thereby in constantly enriching, the theoretical treasure-house of western modern medicine, make the two can both more effectively be human good health and a long life service, but not argue for arguement, even be negative arbitrarily even attack the other side, not science and responsible attitude and behavior because do like this by lack of evidence ground to argue, all be unfavorable for ensureing and developing human medical and health care system.
At present this class disease of control in, Western medicine product substantially all are to lay particular stress on treatment and function singleness, some Chinese medicines use rare or/and contain hormone and the animality medical material of the various toxicity, side effects of being correlated with, and make its resource and service group limited; It is just more common that Western medicine contains hormone, what have is exactly single or the combination hormone purely, not only side effect is big and very easy formation dependency and very expensive, is effective and the safest on the market present Western medicine (Viagra) as " viagra ", and it also promotes exchanging of local patient and doctor.Though they can not tell the doctor that he has suffered from impotence deficiency, but can be direct Xiang doctor's rope prescription purchase medicine, due to illness the people must could buy " viagra " by doctor's dispensing, existing increasing people between 11 to 20 (Australia) units, and has " viagra " to cause heart disease to break out dead case and dispute Xiang doctor's relief, every price; In no matter the more important thing is, the all rarer officinal food dual purpose product of Western medicine, this is to forbid unauthorized medicine to use food (comprising health product) in any form because consider all to make laws from drug safety in China and a lot of countries and regions, otherwise investigate civil and even criminal responsibility in accordance with the law, and that disease reaches the degree of essential treatment is very serious, say on the clinical meaning often to have missed the optimal treatment period and often be difficult to and cure or increase greatly treatment and cure difficulty, medical expense is also very high, many patients and family are difficult to bear, especially developing country is even more serious, the ratio that accounts for total population as China peasant is up to there not being medical care insurance more than 70% substantially, also has the expensive medical fee of same very important laid-off worker and indigent family's financial insolvency, let alone puted prevention first, even if also just can sell medicine as the U.S. because of the prescription drugs pharmacy that must the doctor prescribes in developed country and area, otherwise it is illegal, consumer then must pay expenses such as high prescription takes and surpass medicine valency itself outward, and nonprescription drugs, health food is that the dietotherapeutic product then need not prescription and expensive expense thereof, has alleviated consumer's financial burden greatly and made to buy to consume simple and direct and increase purchasing power, fulfill thereby making puts prevention first.Therefore unique legal effectively, economically feasible, to put prevention first, prevent and treat the scheme of taking into account just can only be screening, combination and design relevant new departure and new product in view of the above in legal dietotherapeutic medicine scope, because of such product could really accomplish good and cheap and meet the inveteracy consumption habit of consumer's " Diet cures more than the doctors ", consumer channel is unblocked, service group is extensive, its disease preventing and treating function and curative effect, safety and crowd's general applicability could also must gain public acceptance and serial relevant law such as state food health legislation is approved and protect.Total be exactly the present invention at prior art not enough, for one for solve an above-mentioned serial difficult problem inventive concept the control impotence and seminal emission medicinal and edible Chinese medicine and the manufacture method that design, main Chinese medicine principle and function, advantage that its health that adopts officinal promulgated by the ministries or commissions of the Central Government is eaten dual-purpose raw material of Chinese medicine and the property of medicine and foundation are described below.
Concha Ostreae is slightly cold, arresting seminal emission hidroschesis, metrorrhagia and leukorrhagia hypochondriac pain, old expectorant go to loose.Concha Ostreae salty in the mouth, cold nature have arresting seminal emission, antisudorific effect, can control emission and spermatorrhea, spontaneous sweating, and control diseases such as women's metrorrhagia and leukorrhagia.Because this product salty in the mouth, again can the old expectorant of softening the hard massization, can control the side of body down heavily fortified point completely have a pain and neck is given birth to sucutaneous nodule, scrofula etc.
Hot, the kind promoting blood circulation of Cortex Cinnamomi, stomachache deficiency and coldness, temperature compensation can get.Cortex Cinnamomi acrid-sweet flavor, extremely hot in nature have the effect of YANG invigorating dispersing cold for relieving pain, are good at warm promoting blood circulation, are applicable to insufficiency of kidney-YANG, aversion to cold and cold limbs, chills and pain of the waist and kness, women's cold in blood amenorrhea, and diseases such as the coldness and pain in the epigastrium of deficiency and coldness, cold diarrhea, all can play the effect of temperature compensation.
Rhizoma Dioscoreae (potato) Gan Wen, reason spleen antidiarrheal, kidney tonifying invigorating middle warmer, all void can be controlled.Potato sweet in the mouth, warm in nature has tonifying the spleen and stomach, stopping leak to rush down effect with nourishing kidney, is applicable to weakness of the spleen and stomach, inappetence, disease such as the chronic dysentery of having loose bowels and emission due to deficiency of the kidney, leukorrhagia, and controls and quench one's thirst, and all can treat the insufficient disease of weakness.
Semen Euryales sweet in the mouth, the beneficial vital essence of energy, Yao Xi Acid pain, all main wet spleen.Semen Euryales sweet-puckery flavor, property are put down, and the effect of the kidney invigorating and essence nourishing is arranged, and can control the Yao Xi Acid pain of suffering from a deficiency of the kidney, and the energy removing dampness, so also effective to arthralgia chiefly caused by damp pathogen arthralgia.This product more has the effect of controlling nocturnal emission with astringent drugs and invigorating the spleen to arrest diarrhea, the seminal emission that can only suffer from a deficiency of the kidney and women's leucorrhea and insufficiency of the spleen chronic dysentery etc. of having loose bowels.This product is the Gorgon fruit.
Semen Nelumbinis sweet in the mouth, spleen invigorating are managed stomach, antidiarrheal arresting seminal emission, are cleared away heart-fire and foster the spirit of nobility.Semen Nelumbinis sweet in the mouth, property are flat, have that tonifying the spleen and stomach, stopping leak rush down, an effect of kidney tonifying arresting seminal emission and benefiting heart-QI, are applicable to insufficiency of the spleen chronic dysentery of having loose bowels, the emission of suffering from a deficiency of the kidney and diseases such as women's leukorrhagia and palpitation and insomnia.Plumula Nelumbinis is embryo tooth, the bitter in the mouth, cold in nature of this product, and the effect of the heat that clears away heart-fire is arranged, and can control the epidemic febrile disease pathogenic heat pericardium that caves in, and the coma of appearance, says paste etc.
The sweet temperature of Fructus Lycii, add the smart marrow, the wind that makes eye bright, cloudy emerging sun mended and rise.Fructus Lycii sweet in the mouth, warm in nature has nourishing kidney to mend bone marrow, nourishing the liver to improve visual acuity and goes the wind effect, and it can yin nourishing, again can be supporing yang, so disease such as clinical impotence and seminal emission, the Yao Xi Acid that is usually used in insufficiency of kidney-YANG be soft also is used for the prosperous disease such as have a dizzy spell of deficiency of the kidney yin, liver-yang.
Endothelium Corneum Gigeriae Galli is cold, the seminal emission of drowning let out, prohibit dysentery leak collapse, heat clearing away and restlessness relieving more.The Endothelium Corneum Gigeriae Galli sweet in the mouth is cold in nature, and the effect of arresting enursis and seminal emission is arranged, and dysentery relieving disease and women's metrorrhagia, can separate heat clearing away and restlessness relieving again.This product mainly contains the long-pending effect that helps digestion, kind control food stagnation stagnate the gastral cavity abdomen that causes full vexed, send out Ai or abdominal distention and have loose bowels etc.
Fructus Rubi is sweet, kidney decreases that essence exhausts, blackly must make eye bright, tonify deficiency is continuous exhausted.The acid of Fructus Rubi sweet in the mouth, property are flat, the liver and the kidney tonifying controlling nocturnal emission with astringent drugs, control suffer from a deficiency of the kidney smart close not solid seminal emission, spermatorrhea, black beard and hair, are the active drugs of the kidney invigorating void.
The hot temperature of Fructus Alpiniae Oxyphyllae, the QI invigorating of calming the nerves, incontinence of urine seminal emission, vomiting are all controlled.The Fructus Alpiniae Oxyphyllae acrid in the mouth is warm in nature, and tranquilizing mind, the kidney invigorating gas are controlled the enuresis or the frequent micturition and the seminal emission of kidney qi deficiency and coldness, again can warming the spleen, control the diseases such as nausea and vomiting of spleen-cold syndrome.
Product of the present invention is by legal dietotherapeutic Chinese crude drug Concha Ostreae 3-10 part, and Cortex Cinnamomi 0.3-1 part, Rhizoma Dioscoreae 3-6 part, Semen Euryales 2-3 part, Semen Nelumbinis 2-4 part, Fructus Lycii 2-4 part, Endothelium Corneum Gigeriae Galli 1.5-3 part, Fructus Rubi 1.5-3 part, Fructus Alpiniae Oxyphyllae 1-3 part are that raw material of Chinese medicine is formed.
The manufacture method of product of the present invention is as follows:
A. decoction pieces type Chinese crude drug Concha Ostreae 3-10 part is on the waiting list in the choosing of raw material Chinese medicine, Cortex Cinnamomi 0.3-1 part, Rhizoma Dioscoreae 3-6 part, Semen Euryales 2-3 part, Semen Nelumbinis 2-4 part, Fructus Lycii 2-4 part, Endothelium Corneum Gigeriae Galli 1.5-3 part, Fructus Rubi 1.5-3 part, Fructus Alpiniae Oxyphyllae 1-3 part joins in the nonmetallic surface such as containers such as fiberglass, enamel of belt stirrer, filter and water bath with thermostatic control heater;
Preparation b. organic and inorganic mixed solvent is got the above ethanol of food stage (solubilized many be insoluble in the material of water and significantly improve drug effect) and adds the dilution of room temperature drinking water that to make ethanol (dense) degree be that alcohol content is the organic mixed solvent (mixed solution for extraction object Chinese medicinal ingredients material different liquids still can be considered solvent) with inorganic two kinds of solvent compositions of the sterilization type of 55-75% (V/V is a volume ratio), and alcoholic strength is lower than 55% or be higher than 75% equal difficulty and reach optimum extraction and sterilization effect;
C. use the described solvent of b to the raw material medicine extract with the described mixed solvent of b join a described added get in the container of whole Chinese crude drugs, addition is advisable for flooding Chinese crude drug fully, hermetic container soaked 20-30 minute, turn on agitator and with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, open filter, 50-100 eye mesh screen isolated by filtration medicinal residues and solution, the centrifugal medicinal residues of 1000-3000 rev/min rotating speed, medicinal liquid is incorporated isolated by filtration solution into, open heating (evaporation) device medicinal residues and medicinal liquid accurately are heated to 78-80 ℃ of ethanol boiling point (to reduce evaporation of water and distillation as far as possible) vaporization ethanol respectively, collect vaporization ethanol and the alcohol gas liquid coolant is changed into liquid ethanol recycling use with in advance online water-cooled condenser with the room temperature cooling water, ensure that extracting solution utmost point low organic solvent is the high-quality of alcohol content, used cooling water extracts water as preheating, these measure and ensures the low energy consumption of production and product, low water consumption, low-cost, and avoided the pollution of organic solvent to environment and product, the airtight f merge extractive liquid, that is equipped with of medicinal liquid is used, medicinal residues add the following d step and proceed to handle;
D. inorganic solvent water to medicinal residues proceed extract at room temperature will the medicinal residues after c handles join in the described empty of a, with the described preheating water of c flood fully, hermetic container room temperature (because of contain the few breeding of bacterium limited guarantee not putrid and deteriorated) soaked Chinese crude drug 20-30 minute, turn on agitator was with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, 150-200 eye mesh screen isolated by filtration medicinal residues and solution add the airtight f merge extractive liquid, that is equipped with of medicinal liquid the following e step with, medicinal residues and proceed processing;
E. inorganic solvent is proceeded to add (height) warm extraction to medicinal residues the medicinal residues after d handles is joined in the described empty of a, flood fully with the described preheating water of c, hermetic container, turn on agitator also stirs with 20-60 rev/min of rotating speed, add simultaneously (height) temperature (so the time contain bacterium may be than d for high) lower the temperature slowly naturally after 3-5 minute to boiling that (summer high temperature was lowered the temperature and can suitably be aided with the room temperature water-cooled too slowly in about 20-30 minute, the same recyclable described preheating water of c of incorporating into of cooling water) continues stripping and energy-saving and water-saving to 60-70 ℃ in order to pharmaceutical compositions, extract and must high temperature could propose and low temperature is not carried most material composition, and make and heat rapidly and evenly, reduce material damage and loss, with further raising drug effect and recovery rate, open filter, 150-200 eye mesh screen isolated by filtration solution and medicinal residues, the medicinal residues that discard behind the centrifugal medicinal residues of 1000-3000 rev/min rotating speed are the acyclic dirts of agricultural soil high-quality fertilizer of returning crop stocks to the field, and medicinal liquid is incorporated isolated by filtration solution into and is equipped with f merge extractive liquid, usefulness;
F. extracting solution merges the medicinal liquid merging with c, d and e extraction, gets Chinese medicine extraction liquid;
G. the preparation of product of the present invention is concentrated to 25-30% weight ratio concentration with Chinese medicine extraction liquid with triple effect or multi-effect evaporator, lactose is added Chinese medicine extraction liquid, is the solution dry matter content that concentration promotes and to be 35-40%, be spray dried into water content and get product below 3%, host or additive as food, nutriment, health product and medicine, consumption is that ordinary production needs an amount of use, no dose limitation by GMP; Any shape such as the sheet of compacting (lactose is compression moulding very easily) one-tenth 0.2-0.4 gram, grain, ball as food, nutriment, health product and medicine, are advised oral every day 2-3 time, each 0.4-0.8 gram, need not the branch of crowd and dosage.
The purposes of product of the present invention, usage and consumption: as food, nutriment, health product and medicine, oral every day 2-3 time, each 0.4-0.8 restrain, and need not the branch of crowd and dosage; As the host or the additive of food, nutriment, health product and medicine, consumption is that ordinary production needs an amount of use, no dose limitation by GMP.
Embodiment:
1, drinks 3 parts of sheet type Chinese crude drug Concha Ostreaes, 0.3 part of Cortex Cinnamomi, 3 parts of Rhizoma Dioscoreaes, 2 parts of Semen Euryaless, 2 parts in Semen Nelumbinis, 2 parts of Fructus Lyciis, 1.5 parts of Endothelium Corneum Gigeriae Galli, 1.5 parts of Fructus Rubies, 1 part of Fructus Alpiniae Oxyphyllae, make compound Chinese medicine by the manufacture method of compound Chinese medicine product of the present invention and get raw produce, product of the present invention is pressed into the Any shape such as sheet, grain, ball of 0.2-0.4 gram, must product.Be mainly used in the daily life health food that puts prevention first.
2, drink 5 parts of sheet type Chinese crude drug Concha Ostreaes, 0.5 part of Cortex Cinnamomi, 4 parts of Rhizoma Dioscoreaes, 3 parts of Semen Euryaless, 3 parts in Semen Nelumbinis, 3 parts of Fructus Lyciis, 2 parts of Endothelium Corneum Gigeriae Galli, 2 parts of Fructus Rubies, 2 parts of Fructus Alpiniae Oxyphyllae, make compound Chinese medicine by the manufacture method of compound Chinese medicine product of the present invention and get raw produce, product of the present invention is pressed into the Any shape such as sheet, grain, ball of 0.2-0.4 gram, must product.Be mainly used in the light patient of the their early stage or the state of an illness.
3, drink 10 parts of sheet type Chinese crude drug Concha Ostreaes, 1 part of Cortex Cinnamomi, 6 parts of Rhizoma Dioscoreaes, 3 parts of Semen Euryaless, 4 parts in Semen Nelumbinis, 4 parts of Fructus Lyciis, 3 parts of Endothelium Corneum Gigeriae Galli, 3 parts of Fructus Rubies, 3 parts of Fructus Alpiniae Oxyphyllae, make compound Chinese medicine by the manufacture method of compound Chinese medicine product of the present invention and get raw produce, the Any shape such as sheet, grain, ball that product of the present invention are pressed into 0.2-0.4 gram get product.Be mainly used in the long or heavier patient of the state of an illness of the course of disease.
Supplementary copy inventive principle and advantage are as follows:
1, having avoided tradition by meat such as a large amount of edible animals such as Canis familiaris L., sheep, cattle, avian and ovum tonifying YANG surplus such as energy, cholesterol to be accumulated causes fat and systemic diseases such as cardiovascular and cerebrovascular vessel such as hypertension, hyperlipidemia; and these diseases are just further impelled increasing the weight of of disease such as sexual impotence; especially the high type premature ejaculation patient of deficiency of YIN fire; the food that inedibility is too hot; as Carnis caprae seu ovis, Carnis Canitis, Passeris montani saturati, cattle and sheep whip etc., in order to avoid increase the weight of the state of an illness.
2, the present invention adopts the low lactose of water absorption to do complexion changed and easy preservation that filler can reduce duration of storage, so storage life is that the commodity shelf life is long, economic worth is high, and constitute most crowds with the little sweet acescency of the little sweet and Fructus Lycii of lactose and like the popular taste products of " acid is sour-sweet sweet " that eat and easily be accepted, so service face and service group are the most extensive, its society and economic benefit are also just apparent naturally.
3; the property of medicine of Chinese prescription medical material is with flat; temperature; cool; it is main and with flat being slightly cold; the temperate zone cold; cold; also take into account simultaneously and liver (gallbladder); relevant other organ of order after one's own heart; lung; spleen; the protection of the function of kidney and coordination; Chinese medicine organic conception and advantage have been demonstrated fully; make drug effect and function more comprehensive and mark; this double controlling; realized that Chinese medicine property of medicine general inclination is in gentle and promote the high boundary of drug effect mutually; and because of the legal dietotherapeutic of all medical materials; effect certainly and do not have a toxic and side effects; be suitable for any crowd and serve wide, these just the present invention to the imbody of the wide main advantages of Chinese medicine adaptive surface.
4, medicine variety and function all are legal medicine-food two-purposes and simple and clear and do not have a dispute, and the multiple state of an illness of prescription adaptation versatile and flexible and select medication properer has been opened up out Chinese medicine and debated disease and execute tool body content and range of application.
5, all medical materials all are conventional varieties and do not have hormone and toxic and side effects, so quality, the source is secure and aboundresources is cheap, product of the present invention can be consumed by vast general patient because of no patient crowd's branch event and obtain and afford to consume, and the realization new and high technology is served lofty aim for the most numerous common people.
6, innovate organic and inorganic mixed solvent and extract at room temperature and reclaim organic solvent and recycle molten and water-soluble substances and energy-conservation joint (cooling) water of Extraction oil with being beneficial to synchronously high-quality and high recovery rate, again with inorganic solvent and room temperature and high temperature combined extractive technique, scheme and technology, ensured extraction overall process asepticize, can carry substantially many to the greatest extent be insoluble in water or be insoluble in oil material and significantly improve drug effect and extract quality and content, and extraction ratio height, with short production cycle, energy-saving and water-saving, product cost is low, do not have (organic solvent) and pollute, its serial comprehensive advantage is traditional decocting and single with organic solvent or water or some other is because of expensive, highly difficult, the product of receiving single (fact proved and the generally acknowledged both at home and abroad compound composition extract of Chinese medicine than single composition extract good effect, this was exactly the essence and the inherent feature place of Chinese medicine originally and was determined by it), recovery rate low and short-term even long duration are difficult to that so-called modern Chinese medicine extractive technique that penetration and promotion uses is difficult to mention in the same breath.
7, become the favorable factor of the defective of China and Asia average 80% above population Lactose enzyme indigestibility absorption for want of (as milk) lactose into disease preventing and treating, can significantly slow down the medicine slow release speed and avoid taking the very big and beyond affordability historic difficult problem of traditional decocting Chinese medicine dose because adopt lactose to replace the starch easily digested and assimilated and dextrin to make adsorbent, adhesive and filler, thereby significantly prolong the efficacy of a drug persistent period and improve curative effect and possible medicine irritation is relieved to bottom line.
More than these also are the great novelty and the practicality of the legal approval of Patent Law.
Test method, data and presentation of results and prompting: disease that product of the present invention is controlled belongs to common frdquently encountered disease so tool is extensively representative, experimenter's voluntary participation.Product of the present invention because of good effect and have no side effect and crowd's branch, so treatment cycle is short and cure rate is high, make test be easy to just satisfactorily be finished, now further be explained as follows (only for reference) with allow keeping in Patent Law about situation under the prerequisite of necessary KNOW-HOW and business secret and please understand: it is 2 groups that totally 40 of the test patients at different sexes, age, 20 people are divided into for one group: one group with product of the present invention and usage and dosage prevent and treat, one group of not medication compares; Test number and time on test reach the equal tool statistical significance of 2 first quarter moons, test number and experimental period so suitable representativeness and credibility are arranged.The result is as follows: none the routine state of an illness of test group personnel with product of the present invention is deepened, and 5 people's no changes are arranged, and has 15 people to improve; The state of an illness promptly is significantly improved after one week than the lighter; The matched group experimenter finds the state of an illness person of increasing the weight of 16 people, and 4 people feel no significant change, none state of an illness improver.Prompting: the state of an illness does not deepen just to prove absolutely that the state of an illness is controlled, is that product of the present invention is effective that the direction that the state of an illness improvement explanation state of an illness is become better reverses, is that product efficacy of the present invention is remarkable.To sum up state, raw material of the present invention, product and method belong to a total inventive concept, economic environmental protection good effect, be suitable for the crowd and market is all very wide, helpfulness and the degree of association are also very high.

Claims (3)

1, control impotence and seminal emission medicinal and edible Chinese medicine is by dietotherapeutic Chinese crude drug Concha Ostreae 3-10 part, Cortex Cinnamomi 0.3-1 part, Rhizoma Dioscoreae 3-6 part, Semen Euryales 2-3 part, Semen Nelumbinis 2-4 part, Fructus Lycii 2-4 part, Endothelium Corneum Gigeriae Galli 1.5-3 part, Fructus Rubi 1.5-3 part, Fructus Alpiniae Oxyphyllae 1-3 part are that raw material of Chinese medicine is formed.
2, the manufacture method of control impotence and seminal emission medicinal and edible Chinese medicine is as follows:
A. decoction pieces type Chinese crude drug Concha Ostreae 3-10 part is on the waiting list in the choosing of raw material Chinese medicine, Cortex Cinnamomi 0.3-1 part, Rhizoma Dioscoreae 3-6 part, Semen Euryales 2-3 part, Semen Nelumbinis 2-4 part, Fructus Lycii 2-4 part, Endothelium Corneum Gigeriae Galli 1.5-3 part, Fructus Rubi 1.5-3 part, Fructus Alpiniae Oxyphyllae 1-3 part joins in the nonmetallic surface container of belt stirrer, filter and water bath with thermostatic control heater;
Preparation b. organic and inorganic mixed solvent is got the above ethanol of food stage and is added the dilution of room temperature drinking water and makes the organic and inorganic mixed solvent that alcohol content is 55-75%V/V;
C. use the described solvent of b to the raw material medicine extract with the described mixed solvent of b join a described added get in the container of whole Chinese crude drugs, addition is advisable for flooding Chinese crude drug fully, hermetic container soaked 20-30 minute, turn on agitator and with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, open filter, 50-100 eye mesh screen isolated by filtration medicinal residues and solution, the centrifugal medicinal residues of 1000-3000 rev/min rotating speed, medicinal liquid is incorporated isolated by filtration solution into, heater accurately is heated to 78-80 ℃ of vaporization of ethanol boiling point ethanol respectively with medicinal residues and medicinal liquid, collect vaporization ethanol and the alcohol gas liquid coolant is changed into liquid ethanol recycling use with in advance online water-cooled condenser with the room temperature cooling water, used cooling water extracts water as preheating, and the airtight f merge extractive liquid, that is equipped with of medicinal liquid is used, medicinal residues add the following d step and proceed to handle;
D. inorganic solvent water to medicinal residues proceed extract at room temperature will the medicinal residues after c handles join in the described empty of a, with the described preheating water of c flood fully, hermetic container soak at room temperature Chinese crude drug 20-30 minute, turn on agitator was with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, 150-200 eye mesh screen isolated by filtration medicinal residues and solution add the airtight f merge extractive liquid, that is equipped with of medicinal liquid the following e step with, medicinal residues and proceed processing;
E. inorganic solvent is proceeded high temperature extraction to medicinal residues the medicinal residues after d handles is joined in the described empty of a, flood fully with the described preheating water of c, hermetic container, turn on agitator also stirs with 20-60 rev/min of rotating speed, being warmed to boiling simultaneously slowly lowered the temperature about 20-30 minute to 60-70 ℃ after 3-5 minute naturally, the summer high temperature cooling can suitably be aided with the room temperature water-cooled too slowly, cooling water reclaims incorporates the described preheating water of c into, open filter, 150-200 eye mesh screen isolated by filtration solution and medicinal residues, discard medicinal residues behind the centrifugal medicinal residues of 1000-3000 rev/min rotating speed, medicinal liquid is incorporated isolated by filtration solution into and is equipped with f merge extractive liquid, usefulness;
F. extracting solution merges the medicinal liquid merging with c, d and e extraction, gets Chinese medicine extraction liquid;
G. the preparation that prevents and treats the impotence and seminal emission medicinal and edible Chinese medicine is concentrated to 25-30% weight ratio concentration with Chinese medicine extraction liquid with triple effect or multi-effect evaporator, lactose is added Chinese medicine extraction liquid, is that concentration promotes and to be 35-40% that being spray dried into water content must product of the present invention 3% below to the solution dry matter content.
3, the purposes of control impotence and seminal emission medicinal and edible Chinese medicine: as food, nutriment, health product and medicine, oral every day 2-3 time, each 0.4-0.8 restrain, and need not the branch of crowd and dosage; As the host or the additive of food, nutriment, health product and medicine, consumption is that ordinary production needs an amount of use, no dose limitation by GMP.
CNB2005101364275A 2005-12-29 2005-12-29 Medicine and food dual purpose Chinese medicine for preventing and treating impotence and seminal emission and its manufacturing method Expired - Fee Related CN100421714C (en)

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