CN100536906C - Application for combination for preparing Chinese medicinal preduct for preventing and treating dizziness flowery vission - Google Patents

Application for combination for preparing Chinese medicinal preduct for preventing and treating dizziness flowery vission Download PDF

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CN100536906C
CN100536906C CNB200510136435XA CN200510136435A CN100536906C CN 100536906 C CN100536906 C CN 100536906C CN B200510136435X A CNB200510136435X A CN B200510136435XA CN 200510136435 A CN200510136435 A CN 200510136435A CN 100536906 C CN100536906 C CN 100536906C
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medicinal residues
liquid
medicinal
chinese medicine
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CN1824282A (en
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颜怀伟
颜怀玮
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Abstract

A Chinese medicine used as both medicine and food for preventing and treating dizziness and blurred vision is prepared from 6 Chinese-medicinal materials including wolfberry fruit, mulberry leaf, mulberry fruit, lotus seed, etc. Its preparing process is also disclosed.

Description

The application of a kind of compositions in Chinese medicine product is felt dizzy in the preparation control
Chinese medicine and western modern medicine disease preventing and treating theory one significantly difference be that the former does not rest on analysis to the concrete cause of disease to pathological knowledge, show the nonantagonistic latter and then be antagonism, that is the former emphasizes is human body integral and the ability that how improves the antagonism disease from integral body, the latter then is that " sitting in the right seat " is as what microorganism, nutrient, poisonous and harmful substance (comprising medicine) and effect etc. cause any disease, though theoretic dispute is very big, even opposition and antagonism, whom shows under a lot of situations whom does not persuade, mutual contradiction or do not have public opinion even, undisputable fact really but they can both be cured the disease and/or reach a cure, this also proved human to medicine especially in, cognitive level and ability between western modern medicine is mutual are also very limited, and arbitrarily in the dogmatize about, the western modern medicine theory who to whose mistake, can not declare that more which is right and which is wrong, because both sides do not have enough conclusive evidences to prove that the other side is wrong, so do not meet the view of science, so should advocate the pardon scientific research of promptly taking facts as the basis and deepen continuously progressively gets and improves relevant theoretical dispute clear with practice and argue, thereby in constantly enriching, the theoretical treasure-house of western modern medicine, make the two can both more effectively be human good health and a long life service, but not argue for arguement, even be negative arbitrarily even attack the other side, not science and responsible attitude and behavior because do like this by lack of evidence ground to argue, all be unfavorable for the guarantee and the development of human medical and health care system; Chinese medicine is that with another remarkable difference of western modern medicine disease preventing and treating the cycle of the former general treatment disease is generally good than the latter than the long prognosis slow but after curing of promptly producing effects of the latter, this and its integrity attribute is closely related so do not have contradiction in itself and can yet be regarded as a good explanation with aforesaid first difference, therefore often to be used to prevent and treat many chronic disease western modern medicines then often opposite for Chinese medicine, and the present invention then can yet be regarded as and belongs to one of case of utilizing this generic attribute of Chinese medicine and characteristics.
Feel dizzy is person in middle and old age's commonly encountered diseases and frequently-occurring disease, particularly the China and even the whole world have faced aging society, and along with modern society's work and the quickening of rhythm of life and the increasing of pressure, many adolescent also too greatly obviously present the situation that becomes younger because of physical and energy overdraw, the lighter that feels dizzy can recover and recover very fast voluntarily, but this is a transient phenomenon, do not influence ill and character, because of Here it is the early warning of body and the beginning of disease, weight person's symptom is more serious, just dizzy immediately as standing slightly soon from low position such as squat position even clinostatism etc., even seriously arrive unexpected dark and dim eyesight, the cold cardiopalmus of face, walk with difficulty or be difficult to stand firm at all and must reduce the stage of position at once, otherwise the danger that falls down to the ground is arranged all whenever and wherever possible, very big to healthy even life and security threat, therefore be worth providing for a rainy day, must take seriously and conscientiously control, can't be because of being that the careless or self-confident youth of chronic disease is not cared about in the least.
At present this class disease of control in, Western medicine product substantially all are to lay particular stress on to treat and function singleness, some Chinese medicines also use the animality medical material, well-known be so that many animality herb resources are few very expensive and unfavorable rare precious animal protection and ecological balance construction, and these products also often contain various hormones and relevant various side effect because of the reason of animality medical material etc., make its service group limited; It is just more common that Western medicine contains hormone, and what have is exactly single or the combination hormone purely, and not only side effect is big and very easy formation dependency; No matter, the all rarer officinal food dual purpose product of Western medicine, this is to forbid unauthorized medicine to use food (comprising health product) in any form because consider all to make laws from drug safety in China and a lot of countries and regions, otherwise investigate civil and even criminal responsibility in accordance with the law, and that disease reaches the degree of essential treatment is very serious, say on the clinical meaning often to have missed the optimal treatment period and often be difficult to and cure or increase greatly treatment and cure difficulty, medical expense is also very high, many patients and family are difficult to bear, especially developing country is even more serious, the ratio that accounts for total population as China peasant is up to there not being medical care insurance more than 70% substantially, also has the expensive medical fee of same very important laid-off worker and indigent family's financial insolvency, let alone puted prevention first, even if also just can sell medicine as the U.S. because of the prescription drugs pharmacy that must the doctor prescribes in developed country and area, otherwise it is illegal, consumer then must pay expenses such as high prescription takes and surpass medicine valency itself outward, and nonprescription drugs, health food is that the dietotherapeutic product then need not prescription and expensive expense thereof, has alleviated consumer's financial burden greatly and made to buy to consume simple and direct and increase purchasing power, fulfill thereby making puts prevention first.Therefore unique legal effectively, economically feasible, to put prevention first, prevent and treat the scheme of taking into account just can only be screening, combination and design relevant new departure and new product in view of the above in legal dietotherapeutic medicine scope, because of such product could really accomplish good and cheap and meet the inveteracy consumption habit of consumer's " Diet cures more than the doctors ", consumer channel is unblocked, service group is extensive, its disease preventing and treating function and curative effect, safety and crowd's general applicability could also must gain public acceptance and serial relevant law such as state food health legislation is approved and protect.Total be exactly the present invention at prior art not enough, for one for solve an above-mentioned serial difficult problem the control that designs of inventive concept feel dizzy medicinal and edible Chinese medicine goods and manufacture method, main Chinese medicine principle and function, advantage that its health that adopts officinal promulgated by the ministries or commissions of the Central Government is eaten dual-purpose raw material of Chinese medicine and the property of medicine and foundation are described below:
The sweet temperature of Fructus Lycii, add the smart marrow, the wind that makes eye bright, cloudy emerging sun mended and rise.Fructus Lycii sweet in the mouth, warm in nature has nourishing kidney to mend bone marrow, nourishing the liver to improve visual acuity and goes the wind effect, and it can yin nourishing, again can be supporing yang, so disease such as clinical impotence and seminal emission, the Yao Xi Acid that is usually used in insufficiency of kidney-YANG be soft also is used for the prosperous disease such as have a dizzy spell of deficiency of the kidney yin, liver-yang.
Folium Mori are cold in nature, the kind wind heat of loosing, the liver heat removing that makes eye bright, the removing heat from blood of holding concurrently again.Folium Mori sweet-bitter flavor, cold in nature, light weight is kind can dispelling wind and heat pathogens, cold in nature again can liver heat removing and eyesight improving, so diseases such as having a dizzy spell of can controlling that fever and cough, headache conjunctival congestion and the liver-yang of affection due to external wind and heat rise, this product also has the effect of lung moistening removing heat from blood concurrently in addition, can control dryness-heat impairing the lung, hemoptysis pharyngalgia etc.
Folium Camelliae sinensis bitter in the mouth cold nature, resolving heat and reducing pathogenic fire are controlled diseases such as the vertigo, mental weariness.
Rhizoma Zingiberis Recens gods warm in nature, unobstructed, phlegmatic cough vomiting, extremely spirit of appetizing.Rhizoma Zingiberis Recens acrid in the mouth, slightly warm in nature have refreshment, preventing or arresting vomiting, dispersing wind and cold effect, and the soldier of bad odor so faints and the vomiting of cold syndrome of the stomach in can controlling, and lung has cold-evil's abundant expectoration cough.In addition can also appetite stimulator, the effect of appetizing is good.
Milk powder sweet in the mouth saltiness is flat, nourishing YIN Yiyang, please that face makes eye bright, vigorate qi and replenish the blood, controls the red and swollen puckery pain of binocular, makes eye bright, and curative effect is very good, and what can also promote important antioxidant glutathione synthesizes, is beneficial to the ability of improving body opposing aging and disease.Glutathion be one natural in the destructive antioxidant of opposing free radical, help the liver protecting to avoid the infringement of poisonous substance and some drugs.Yet directly take glutathion is not a wise move because its to belong to peptide class be the protein amino acid substance, most ofly during through digestive tract can seldom can be entered blood by gastric acid and digestive tract proteolytic enzyme digest.Therefore pharmacy seldom has the glutathion tonic to sell, but as taking the effect that the tonic that can make body produce more glutathion then can reach the compensation glutathion equally and remove free radical.Therefore the method for best raising body glutathion inside level is to take in the raw material of enough synthesizing glutathions, taking lactalbumin is to increase the synthetic effective ways of body glutathion inside: scientist has compared the influence to glutathion inside of 20 gram lactalbumins, placebo and 20 gram caseins in 20 health volunteers, found that lactalbumin can make glutathione level rising 20% in the blood, shows and can improve antioxidant status.One of them explanation is because contain a kind of sulfur-containing amino acid---cysteine in the milk surum, replenishes the glutathione level that nitrogen acetylcysteine (NAC) can improve human body.But the nitrogen acetylcysteine of long-term overdose might bring side effect, shows that because of experiment is arranged exacting practice (producing a large amount of free radicals) back takes the nitrogen acetylcysteine in conjunction with vitamin C and can make on the contrary that the interior free yl level raises, and the remarkable infringement degree of increase muscle! So the effect about it is also not too clear and definite, does not recommend to be used for improving glutathione level.Therefore, lactalbumin is taken in recommendation rather than the nitrogen acetylcysteine stimulates body glutathion inside level, and that milk powder contains abundant lactalbumin, other nutrient substance is also very abundant, is undoubtedly superior choosing, adopts one of milk powder major reason so this also is the present invention.
Herba Moslae acrid in the mouth, Sunstroke are just puckery, the random edema of the leaves of pulse plants, relieving restlessness are analgesic.Herba Moslae acrid in the mouth, slightly warm in nature have that diaphoresis is driven away summer heat, an effect of tonneau urine, can control diseases such as experiencing hot urination that heat-damp in summer causes and vomiting and diarrhoea summer, also control because of the wet edema disease that occurs of water, have again that the summer-heat of releasing is evil to be tired of effect.
Fructus Mori sweet in the mouth, cold in nature, the effect that nourishing YIN to relieve dryness is arranged and enrich blood, the dry property and the treatment deficiency of YIN that can remove mineral metal and stone medicine have the thirsty of heat, but and external hair dyeing, also can control early whitening of hair.The clinical withered constipation of lassitude, dizzy insomnia and blood deficiency intestinal juice etc. that are used for of this product more.
Semen Nelumbinis sweet in the mouth, spleen invigorating are managed stomach, antidiarrheal arresting seminal emission, are cleared away heart-fire and foster the spirit of nobility.Semen Nelumbinis sweet in the mouth, property are flat, have that tonifying the spleen and stomach, stopping leak rush down, an effect of kidney tonifying arresting seminal emission and benefiting heart-QI, are applicable to insufficiency of the spleen chronic dysentery of having loose bowels, the emission of suffering from a deficiency of the kidney and diseases such as women's leukorrhagia and palpitation and insomnia.Plumula Nelumbinis is embryo tooth, the bitter in the mouth, cold in nature of this product, and the effect of the heat that clears away heart-fire is arranged, and can control the epidemic febrile disease pathogenic heat pericardium that caves in, and the coma of appearance, says paste etc.
Herba Portulacae is cold, optic atrohic blindness nebula, salty the controlling of convenient parasite killing, Disorder carbuncle.The Herba Portulacae sour in the mouth is cold in nature, and the loose effect of blood of heat clearing away, detoxifcation, parasite killing is arranged, and can control the blurring of vision that pyretic toxicity causes or gives birth to the nebula film and swell and ache and toxic-heat and blood stasis.In addition, can loose blood so all can treat because of this product to not all right De mass in the abdomen of blood stasis and carbuncle.
Pericarpium Zanthoxyli is hot, uncharm by the parasite killing of trembling with fear, make eye bright, temperature and not violent.The Pericarpium Zanthoxyli acrid in the mouth is warm in nature, the warming the spleen stomach is arranged, by cold-damp, parasiticidal effect, be applicable to diseases such as breast abdomen cold type of pain or dysentery stomachache and vomiting ascarid, fiercely can also not make eye bright so it is warm in nature.
Fructus Gardeniae is cold in nature, removing stagnation to relieve restlessness, tell nosebleed stomachache, and urine falls in fire.Fructus Gardeniae bitter in the mouth, cold in nature has the heat clearing away effect, can remove hot and suffocating vexed uneasiness, and can the removing heat from blood hemorrhoidal bleeding.Control hemorrhages such as haematemesis, nose bleeding.In addition, also can control the stomach burning pain.This product can make heat discharge from urine.This product is also controlled disease such as the hemorrhage and pyretic toxicity carbuncle of jaundice disease, the defecation of hot and suffocating conjunctival congestion and swelling pain, whole body jaundice.Give birth to heat clearing away, fry black hemostasis, Sucus Zingberis fry control tiredly vomit, exterior heat or loose stool be with skin, interior-heat core.
The Arillus Longan sweet in the mouth, return spleen Fructus Alpiniae Oxyphyllae, forgetful palpitation with a distress feeling, clever wide note.Arillus Longan sweet in the mouth, property are put down, and the master goes into heart spleen two warps, has spleen reinforcing to nourish heart, strengthen the effect of wisdom, can control the palpitation and restlessness and the hypomnesis that cause because of the spleen blood deficiency, and people's intelligence is strengthened.
The Bulbus Lilii sweet in the mouth, feel at ease to decide disappear floating, carbuncle of gallbladder, antitussive and can eat.Bulbus Lilii sweet in the mouth, cold nature have the effect that clears away heart-fire, calms the nerves, calms the frightened, and can control vexed palpitation with fear, mind uneasiness, be that what is called feels at ease to decide gallbladder lung moistening, cough-relieving, diuretic effect are arranged, so control cough due to lung-heat and edema disease again again.In addition, outer disease such as carbuncle also oral administration, can play the effect of heat-clearing and toxic substances removing.
The heat clearing away of chrysanthemum powder forimproving wind, suppressing the hyperactive liver makes eye bright.Be used for anemopyretic cold, it is dizzy to have a headache, conjunctival congestion and swelling pain, and eyes is dim-sighted.
The hot temperature of Fructus Alpiniae Oxyphyllae, the QI invigorating of calming the nerves, incontinence of urine seminal emission, vomiting are all controlled.The Fructus Alpiniae Oxyphyllae acrid in the mouth is warm in nature, and tranquilizing mind, the kidney invigorating gas are controlled the enuresis or the frequent micturition and the seminal emission of kidney qi deficiency and coldness, again can warming the spleen, control diseases such as spleen-cold syndrome nausea and vomiting.
Sweet flat, the cough-relieving pus and blood of Colla Corii Asini, haematemesis tire collapse, empty win can be obeyed.The Colla Corii Asini sweet in the mouth is flat, enriches blood, hemostasis, nourishing YIN and moistening the lung, control cough due to consumptive disease, haematemesis, spit blood, have blood in stool and woman uterine bleeding or pregnant woman uterus hemorrhage etc., the dysphoria with smothery sensation in the heart that the deficiency of YIN also can be taken, also be controlled to body void disease such as must not sleep peacefully.Molten is used as medicine and is taken, goes into soup and fry in shallow oil and must fry use.
The Rhizoma Polygonati sweet in the mouth, can pacify internal organs, five kinds of strain and seven kinds of impairment, the big benefit of this medicine.Rhizoma Polygonati sweet in the mouth, property are flat, the spleen reinforcing lung moistening, and it is sick as weakness of the spleen and stomach, cough due to deficiency of the lung and disease such as quench one's thirst to control the deficient impairment caused by overstrain of internal organs.Five kinds of strain and seven kinds of impairment: hepatic asthenia, the impairment of the heart caused by overstrain, the impairment of the spleen due to overstrain, impairment of the kidney caused by overstrain; The big full impairment of the spleen, rage QI rising in reverse order impairing the liver, powerful weight lifting sitting wetland are impairment of the kidney, cold physique drink cold injury lung, sorrow are pondered over sad, wind and rain abnormal weather changes being apt to injure configuration of the body, big fear does not save the impairment of mentality.
Product of the present invention is made of for raw material in right amount legal dietotherapeutic Chinese medicine Fructus Lycii 2-4 part, Folium Mori 1-3 part, Folium Camelliae sinensis 1-2 part, Rhizoma Zingiberis Recens 1-2 part, Herba Moslae 0-3 part, Fructus Mori 0-5 part, Semen Nelumbinis 0-4 part, Herba Portulacae 0-3 part, Pericarpium Zanthoxyli 0-1 part, Fructus Gardeniae 0-3 part, Arillus Longan 0-3 part, Bulbus Lilii 0-3 part, Flos Chrysanthemi 1-3 part, Fructus Alpiniae Oxyphyllae 1-3 part, Colla Corii Asini 2-4 part, Rhizoma Polygonati 3-5 part and milk powder.
The manufacture method of product of the present invention is as follows:
A. 24 parts of decoction pieces type Chinese crude drug Fructus Lyciis, Folium Mori 1-3 part, Folium Camelliae sinensis 1-2 part, Rhizoma Zingiberis Recens 1-2 part, Herba Moslae 0-3 part, Fructus Mori 0-5 part, Semen Nelumbinis 0-4 part, Herba Portulacae 0-3 part, Pericarpium Zanthoxyli 0-1 part, Fructus Gardeniae 0-3 part, Arillus Longan 0-3 part, Bulbus Lilii 0-3 part, Flos Chrysanthemi 1-3 part, Fructus Alpiniae Oxyphyllae 1-3 part, Colla Corii Asini 2-4 part, Rhizoma Polygonati 3-5 part are on the waiting list in the choosing of raw material Chinese medicine, join in the nonmetallic surface such as containers such as fiberglass, enamel of belt stirrer, filter and water bath with thermostatic control heater;
Preparation b. organic and inorganic mixed solvent is got the above ethanol of food stage (solubilized many be insoluble in the material of water and significantly improve drug effect) and adds the dilution of room temperature drinking water that to make ethanol (dense) degree be that alcohol content is the organic mixed solvent (mixed solution for extraction object Chinese medicinal ingredients material different liquids still can be considered solvent) with inorganic two kinds of solvent compositions of the sterilization type of 55-75% (V/V is a volume ratio), and alcoholic strength is lower than 55% or be higher than 75% equal difficulty and reach optimum extraction and sterilization effect;
C. use the described solvent of b to the raw material medicine extract with the described mixed solvent of b join a described added get in the container of whole Chinese crude drugs, addition is advisable for flooding Chinese crude drug fully, hermetic container soaked 20-30 minute, turn on agitator and with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, open filter, 50-100 eye mesh screen isolated by filtration medicinal residues and solution, the centrifugal medicinal residues of 1000-3000 rev/min rotating speed, medicinal liquid is incorporated isolated by filtration solution into, open heating (evaporation) device medicinal residues and medicinal liquid accurately are heated to 78-80 ℃ of ethanol boiling point (to reduce evaporation of water and distillation as far as possible) vaporization ethanol respectively, collect vaporization ethanol and the alcohol gas liquid coolant is changed into liquid ethanol recycling use with in advance online water-cooled condenser with the room temperature cooling water, ensure that extracting solution utmost point low organic solvent is the high-quality of alcohol content, used cooling water extracts water as preheating, these measure and ensures the low energy consumption of production and product, low water consumption, low-cost, and avoided the pollution of organic solvent to environment and product, the airtight f merge extractive liquid, that is equipped with of medicinal liquid is used, medicinal residues add the following d step and proceed to handle;
D. inorganic solvent water to medicinal residues proceed extract at room temperature will the medicinal residues after c handles join in the described empty of a, with the described preheating water of c flood fully, hermetic container room temperature (because of contain the few breeding of bacterium limited guarantee not putrid and deteriorated) soaked Chinese crude drug 20-30 minute, turn on agitator was with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, 150-200 eye mesh screen isolated by filtration medicinal residues and solution add the airtight f merge extractive liquid, that is equipped with of medicinal liquid the following e step with, medicinal residues and proceed processing;
E. inorganic solvent is proceeded to add (height) warm extraction to medicinal residues the medicinal residues after d handles is joined in the described empty of a, flood fully with the described preheating water of c, hermetic container, turn on agitator also stirs with 20-60 rev/min of rotating speed, add simultaneously (height) temperature (so the time contain bacterium may be than d for high) lower the temperature slowly naturally after 3-5 minute to boiling that (summer high temperature was lowered the temperature and can suitably be aided with the room temperature water-cooled too slowly in about 20-30 minute, the same recyclable described preheating water of c of incorporating into of cooling water) continues stripping and energy-saving and water-saving to 60-70 ℃ in order to pharmaceutical compositions, extract and must high temperature could propose and low temperature is not carried most material composition, and make and heat rapidly and evenly, reduce material damage and loss, with further raising drug effect and recovery rate, open filter, 150-200 eye mesh screen isolated by filtration solution and medicinal residues, the medicinal residues that discard behind the centrifugal medicinal residues of 1000-3000 rev/min rotating speed are the acyclic dirts of agricultural soil high-quality fertilizer of returning crop stocks to the field, and medicinal liquid is incorporated isolated by filtration solution into and is equipped with f merge extractive liquid, usefulness;
F. extracting solution merges the medicinal liquid merging with c, d and e extraction, gets Chinese medicine extraction liquid;
G. the preparation of product of the present invention is concentrated to 25-30% weight ratio concentration with Chinese medicine extraction liquid with triple effect or multi-effect evaporator, add Chinese medicine extraction liquid, be the solution dry matter content that concentration promotes and is 35-40% by milk powder 3-5 part and lactose 1-3 part part by weight, be spray dried into water content and get product below 3%, host or additive as food, nutriment, health product and medicine, consumption is that ordinary production needs an amount of use, no dose limitation by GMP; Compacting (lactose and all very easily compression moulding of milk powder) becomes Any shape such as the sheet, grain, ball of 0.2-0.4 gram, as food, nutriment, health product and medicine, advises oral every day 2-3 time, 0.4-0.8 restrains at every turn, need not the branch of crowd and dosage.
The purposes of product of the present invention, usage and consumption: as food, nutriment, health product and medicine, oral every day 2-3 time, each 0.4-0.8 restrain, and need not the branch of crowd and dosage; As the host or the additive of food, nutriment, health product and medicine, consumption is that ordinary production needs an amount of use, no dose limitation by GMP.
Embodiment:
1, drinks 2 parts of sheet type Chinese crude drug Fructus Lyciis, 1 part on Folium Mori, 1 part of Folium Camelliae sinensis, 1 part in Rhizoma Zingiberis Recens, 1 part of Flos Chrysanthemi, 1 part of Fructus Alpiniae Oxyphyllae, 2 parts in Colla Corii Asini, 3 parts of Rhizoma Polygonatis, make compound Chinese medicine by the manufacture method of compound Chinese medicine product of the present invention and get raw produce, product of the present invention is pressed into the Any shape such as sheet, grain, ball of 0.2-0.4 gram, must product.Be mainly used in the daily life health food that puts prevention first.
2, drink 2 parts of sheet type Chinese crude drug Fructus Lyciis, 2 parts on Folium Mori, 2 parts of Folium Camelliae sinensis, 1 part in Rhizoma Zingiberis Recens, 1 part of Herba Moslae, 1 part in Fructus Mori, 1 part in Semen Nelumbinis, 1 part of Fructus Gardeniae, 1 part of Arillus Longan, 1 part of Flos Chrysanthemi, 1 part of Fructus Alpiniae Oxyphyllae, 2 parts in Colla Corii Asini, 3 parts of Rhizoma Polygonatis, make compound Chinese medicine by the manufacture method of compound Chinese medicine product of the present invention and get raw produce, product of the present invention is pressed into the Any shape such as sheet, grain, ball of 0.2-0.4 gram, must product.Be mainly used in the light patient of the their early stage or the state of an illness.
3, drink 2 parts of sheet type Chinese crude drug Fructus Lyciis, 2 parts on Folium Mori, 2 parts of Folium Camelliae sinensis, 1 part in Rhizoma Zingiberis Recens, 1 part of Herba Moslae, 1 part in Fructus Mori, 1 part in Semen Nelumbinis, Herba Portulacae 1,0.5 part in Pericarpium Zanthoxyli, 1 part of Fructus Gardeniae, 1 part of Arillus Longan, 1 part of Bulbus Lilii, 1 part of Flos Chrysanthemi, 1 part of Fructus Alpiniae Oxyphyllae, 2 parts in Colla Corii Asini, 3 parts of Rhizoma Polygonatis, make compound Chinese medicine by the manufacture method of compound Chinese medicine product of the present invention and get raw produce, the Any shape such as sheet, grain, ball that product of the present invention are pressed into 0.2-0.4 gram get product.Be mainly used in the long or heavier patient of the state of an illness of the course of disease.
4, drink 4 parts of sheet type Chinese crude drug Fructus Lyciis, 3 parts on Folium Mori, 2 parts of Folium Camelliae sinensis, 2 parts in Rhizoma Zingiberis Recens, 3 parts of Herba Moslaes, 5 parts in Fructus Mori, 4 parts in Semen Nelumbinis, 3 parts of Herba Portulacaes, 1 part in Pericarpium Zanthoxyli, 3 parts of Fructus Gardeniaes, 3 parts of Arillus Longans, 3 parts of Bulbus Liliies, 3 parts of Flos Chrysanthemis, 3 parts of Fructus Alpiniae Oxyphyllae, 4 parts in Colla Corii Asini, 5 parts of Rhizoma Polygonatis, make compound Chinese medicine by the manufacture method of compound Chinese medicine product of the present invention and get raw produce, the Any shape such as sheet, grain, ball that product of the present invention are pressed into 0.2-0.4 gram get product.Be used for the patient with severe symptoms.
Supplementary copy inventive principle and advantage are as follows:
1, the present invention adopts the low lactose of water absorption to do complexion changed and easy preservation that filler can reduce duration of storage, so storage life is that the commodity shelf life is long, economic worth is high; And form most crowds jointly with the acescency of little sweet taste of lactose etc. and Fructus Lycii etc. and like the popular taste products of " little sweet little acid " of eating and easily be accepted, so service face and service group are the most extensive, its society and economic benefit are naturally also with regard to obviously.
2; the property of medicine of Chinese prescription medical material is with flat; cool; it is main and cold with the torrid zone being slightly cold; with temperature; flat rubber belting is slightly cold etc.; also take into account simultaneously and liver (gallbladder); relevant other organ of order after one's own heart; lung; spleen; the protection of the function of kidney and coordination; Chinese medicine organic conception and advantage have been demonstrated fully; make drug effect and function more comprehensive and mark; this double controlling; realized that Chinese medicine property of medicine general inclination is in gentle and promote the high boundary of drug effect mutually; especially can regulate application simultaneously with the medicine of Yin Yang balancing strength; thereby make the moon; sun balance of force and mutual regulating power all can reach balance and gentle; all kinds of diseases and ailments are spontaneous recovery; and because of the legal dietotherapeutic of all medical materials; effect certainly and do not have a toxic and side effects; be suitable for any crowd and serve wide, this just the present invention to the imbody of the wide main advantages of Chinese medicine adaptive surface.
3, medicine variety and function all are legal medicine-food two-purposes and simple and clear and do not have a dispute, and the multiple state of an illness of prescription adaptation versatile and flexible and select medication properer has been opened up out Chinese medicine and debated disease and execute tool body content and range of application.
4, all medical materials all are conventional varieties and do not have hormone and toxic and side effects, so quality, the source is secure and aboundresources is cheap, product of the present invention can be consumed by vast general patient because of no patient crowd's branch event and obtain and afford to consume, and the realization new and high technology is served lofty aim for the most numerous common people.
5, innovate organic and inorganic mixed solvent and extract at room temperature and reclaim organic solvent and recycle molten and water-soluble substances and energy-conservation joint (cooling) water of Extraction oil with being beneficial to synchronously high-quality and high recovery rate, again with inorganic solvent and room temperature and high temperature combined extractive technique, scheme and technology, ensured extraction overall process asepticize, can carry substantially many to the greatest extent be insoluble in water or be insoluble in oil material and significantly improve drug effect and extract quality and content, and extraction ratio height, with short production cycle, energy-saving and water-saving, product cost is low, do not have (organic solvent) and pollute, its serial comprehensive advantage is traditional decocting and single with organic solvent or water or some other is because of expensive, highly difficult, the product of receiving single (fact proved and the generally acknowledged both at home and abroad compound composition extract of Chinese medicine than single composition extract good effect, this was exactly the essence and the inherent feature place of Chinese medicine originally and was determined by it), recovery rate low and short-term even long duration are difficult to that so-called modern Chinese medicine extractive technique that penetration and promotion uses is difficult to mention in the same breath.
6, become the favorable factor of the defective of China and Asia average 80% above population Lactose enzyme indigestibility absorption for want of (as milk) lactose into disease preventing and treating, because adopt lactose to replace the starch of easily digesting and assimilating and dextrin is made adsorbent and filler can significantly slow down the medicine slow release speed and avoid taking a very Peter Pans historic difficult problem beyond affordability of traditional decocting Chinese medicine amount, thereby significantly prolong the efficacy of a drug persistent period and improve curative effect and possible medicine irritation is relieved to bottom line.
More than these also are the great novelty and the practicality of the legal approval of Patent Law.
Test method, data and presentation of results and prompting:
Disease that product of the present invention is controlled belongs to common frdquently encountered disease so tool is extensively representative, experimenter's voluntary participation.Product of the present invention because of good effect and have no side effect and crowd's branch, so treatment cycle is short and cure rate is high, make test be easy to just satisfactorily be finished, now further be explained as follows (only for reference) with allow keeping in Patent Law about situation under the prerequisite of necessary KNOW-HOW and business secret and please understand: it is 2 groups that totally 40 of the test patients at different sexes, age, 20 people are divided into for one group: one group with product of the present invention and usage and dosage prevent and treat, one group of not medication compares; Test number and time on test reach the equal tool statistical significance of 2 first quarter moons, test number and experimental period so suitable representativeness and credibility are arranged.The result is as follows: none the routine state of an illness of test group personnel with product of the present invention is deepened, and 5 people's no changes are arranged, and has 15 people to improve; The state of an illness is than the lighter's promptly be significantly improved after one week, not only can stand up rapidly behind the especially dizzy person 2-3 days unlikely astasia and substantially unconsciously pupil is or/and have a dizzy spell, and this also belongs to more rare instant effect, eutherapeutic example in the chronic disease treatment by Chinese herbs; The matched group experimenter finds the state of an illness person of increasing the weight of 16 people, and 4 people feel no significant change, none state of an illness improver.Prompting: the state of an illness does not deepen just to prove absolutely that the state of an illness is controlled, is that product of the present invention is effective that the direction that the state of an illness improvement explanation state of an illness is become better reverses, is that product efficacy of the present invention is remarkable.
To sum up state, raw material of the present invention, product and method belong to a total inventive concept, economic environmental protection good effect, be suitable for the crowd and market is all very wide, helpfulness and the degree of association are also very high.

Claims (1)

1, the application of a kind of compositions in Chinese medicine product is felt dizzy in preparation control is characterized in that it makes by following step:
A. drink sheet type Chinese crude drug Fructus Lycii 2-4 part, Folium Mori 1-3 part, Folium Camelliae sinensis 1-2 part, Rhizoma Zingiberis Recens 1-2 part, Herba Moslae 0-3 part, Fructus Mori 0-5 part, Semen Nelumbinis 0-4 part, Herba Portulacae 0-3 part, Pericarpium Zanthoxyli 0-1 part, Fructus Gardeniae 0-3 part, Arillus Longan 0-3 part, Bulbus Lilii 0-3 part, Flos Chrysanthemi 1-3 part, Fructus Alpiniae Oxyphyllae 1-3 part, Colla Corii Asini 2-4 part, Rhizoma Polygonati 3-5 part, join in the nonmetallic surface container of belt stirrer, filter and water bath with thermostatic control heater;
Preparation b. organic and inorganic mixed solvent is got the above ethanol of food stage and is added the dilution of room temperature drinking water and makes the mixed solvent that alcohol concentration is the organic and inorganic two kinds of solvent compositions of the sterilization type of 55-75%V/V;
C. use the described solvent of b to the raw material medicine extract with the described mixed solvent of b join a described added get in the container of whole Chinese crude drugs, addition is for flooding Chinese crude drug fully, hermetic container soaked 20-30 minute, turn on agitator and with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, open filter, 50-100 eye mesh screen isolated by filtration medicinal residues and solution, the centrifugal medicinal residues of 1000-3000 rev/min rotating speed, medicinal liquid is incorporated isolated by filtration solution into, open heating fumigators medicinal residues and medicinal liquid accurately are heated to 78-80 ℃ of vaporization of ethanol boiling point ethanol respectively, collect vaporization ethanol and the alcohol gas liquid coolant is changed into liquid ethanol recycling use with in advance online water-cooled condenser with the room temperature cooling water, used cooling water extracts water as preheating, and the airtight f merge extractive liquid, that is equipped with of medicinal liquid is used, medicinal residues add the following d step and proceed to handle;
D. water to medicinal residues proceed extract at room temperature will the medicinal residues after c handles join in the described empty of a, with the described preheating water of c flood fully, hermetic container soak at room temperature Chinese crude drug 20-30 minute, turn on agitator was with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, 150-200 eye mesh screen isolated by filtration medicinal residues and solution add the airtight f merge extractive liquid, that is equipped with of medicinal liquid the following e step with, medicinal residues and proceed processing;
E. water is proceeded to heat to extract to medicinal residues the medicinal residues after d handles is joined in the described empty of a, flood fully with the described preheating water of c, hermetic container, turn on agitator also stirs with 20-60 rev/min of rotating speed, being warmed to boiling simultaneously slowly lowered the temperature about 20-30 minute to 60-70 ℃ after 3-5 minute naturally, the summer high temperature cooling suitably is aided with the room temperature water-cooled too slowly, cooling water reclaims incorporates the described preheating water of c into, open filter, 150-200 eye mesh screen isolated by filtration solution and medicinal residues, 1000-3000 rev/min rotating speed is centrifugal, medicinal liquid is incorporated isolated by filtration solution into and is equipped with f merge extractive liquid, usefulness;
F. extracting solution merges the medicinal liquid merging with c, d and e extraction, gets Chinese medicine extraction liquid;
G. the preparation that prevents and treats the Chinese medicine product of feeling dizzy is concentrated to 25-30% weight ratio concentration with Chinese medicine extraction liquid with triple effect or multi-effect evaporator, add Chinese medicine extraction liquid, be the solution dry matter content that concentration promotes and is 35-40% by milk powder 3-5 part and lactose 1-3 part part by weight, be spray dried into water content and get raw material below 3%, the sheet, grain, the ball that are pressed into the 0.2-0.4 gram get product.
CNB200510136435XA 2005-12-29 2005-12-29 Application for combination for preparing Chinese medicinal preduct for preventing and treating dizziness flowery vission Expired - Fee Related CN100536906C (en)

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Address after: No. two, section 17, West Ring Road, Chengdu, Sichuan

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