CN1823613A - Controlled slow release type rare-earth feed additive and its preparation and use method - Google Patents
Controlled slow release type rare-earth feed additive and its preparation and use method Download PDFInfo
- Publication number
- CN1823613A CN1823613A CNA2006100500845A CN200610050084A CN1823613A CN 1823613 A CN1823613 A CN 1823613A CN A2006100500845 A CNA2006100500845 A CN A2006100500845A CN 200610050084 A CN200610050084 A CN 200610050084A CN 1823613 A CN1823613 A CN 1823613A
- Authority
- CN
- China
- Prior art keywords
- earth
- rare
- rare earth
- release type
- slow release
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229910052761 rare earth metal Inorganic materials 0.000 title claims description 134
- 150000002910 rare earth metals Chemical class 0.000 title claims description 88
- 238000000034 method Methods 0.000 title claims description 17
- 238000002360 preparation method Methods 0.000 title claims description 12
- 239000003674 animal food additive Substances 0.000 title 1
- 239000010457 zeolite Substances 0.000 claims abstract description 54
- 229910021536 Zeolite Inorganic materials 0.000 claims abstract description 51
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 claims abstract description 51
- 238000006243 chemical reaction Methods 0.000 claims abstract description 12
- 238000005342 ion exchange Methods 0.000 claims abstract description 4
- -1 rare earth salt Chemical class 0.000 claims description 35
- 239000002002 slurry Substances 0.000 claims description 33
- 229910052746 lanthanum Inorganic materials 0.000 claims description 29
- FZLIPJUXYLNCLC-UHFFFAOYSA-N lanthanum atom Chemical compound [La] FZLIPJUXYLNCLC-UHFFFAOYSA-N 0.000 claims description 29
- 241001465754 Metazoa Species 0.000 claims description 21
- 238000003756 stirring Methods 0.000 claims description 16
- 239000000725 suspension Substances 0.000 claims description 16
- KWYUFKZDYYNOTN-UHFFFAOYSA-M Potassium hydroxide Chemical compound [OH-].[K+] KWYUFKZDYYNOTN-UHFFFAOYSA-M 0.000 claims description 14
- 229910052684 Cerium Inorganic materials 0.000 claims description 13
- GWXLDORMOJMVQZ-UHFFFAOYSA-N cerium Chemical compound [Ce] GWXLDORMOJMVQZ-UHFFFAOYSA-N 0.000 claims description 13
- 230000001105 regulatory effect Effects 0.000 claims description 11
- 229910052777 Praseodymium Inorganic materials 0.000 claims description 10
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 claims description 10
- PUDIUYLPXJFUGB-UHFFFAOYSA-N praseodymium atom Chemical compound [Pr] PUDIUYLPXJFUGB-UHFFFAOYSA-N 0.000 claims description 10
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 10
- 230000018044 dehydration Effects 0.000 claims description 9
- 238000006297 dehydration reaction Methods 0.000 claims description 9
- 239000012065 filter cake Substances 0.000 claims description 9
- 238000001514 detection method Methods 0.000 claims description 8
- 229910017604 nitric acid Inorganic materials 0.000 claims description 8
- 238000010521 absorption reaction Methods 0.000 claims description 7
- 229910052779 Neodymium Inorganic materials 0.000 claims description 6
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 6
- 239000007864 aqueous solution Substances 0.000 claims description 6
- QEFYFXOXNSNQGX-UHFFFAOYSA-N neodymium atom Chemical compound [Nd] QEFYFXOXNSNQGX-UHFFFAOYSA-N 0.000 claims description 6
- 229910052727 yttrium Inorganic materials 0.000 claims description 6
- VWQVUPCCIRVNHF-UHFFFAOYSA-N yttrium atom Chemical compound [Y] VWQVUPCCIRVNHF-UHFFFAOYSA-N 0.000 claims description 6
- 229910052691 Erbium Inorganic materials 0.000 claims description 5
- 229910052688 Gadolinium Inorganic materials 0.000 claims description 5
- 229910052771 Terbium Inorganic materials 0.000 claims description 5
- UYAHIZSMUZPPFV-UHFFFAOYSA-N erbium Chemical compound [Er] UYAHIZSMUZPPFV-UHFFFAOYSA-N 0.000 claims description 5
- UIWYJDYFSGRHKR-UHFFFAOYSA-N gadolinium atom Chemical compound [Gd] UIWYJDYFSGRHKR-UHFFFAOYSA-N 0.000 claims description 5
- 244000144972 livestock Species 0.000 claims description 5
- 239000000203 mixture Substances 0.000 claims description 5
- GZCRRIHWUXGPOV-UHFFFAOYSA-N terbium atom Chemical compound [Tb] GZCRRIHWUXGPOV-UHFFFAOYSA-N 0.000 claims description 5
- 229910052772 Samarium Inorganic materials 0.000 claims description 4
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 claims description 4
- 239000012670 alkaline solution Substances 0.000 claims description 4
- KZUNJOHGWZRPMI-UHFFFAOYSA-N samarium atom Chemical compound [Sm] KZUNJOHGWZRPMI-UHFFFAOYSA-N 0.000 claims description 4
- 229910052706 scandium Inorganic materials 0.000 claims description 4
- SIXSYDAISGFNSX-UHFFFAOYSA-N scandium atom Chemical compound [Sc] SIXSYDAISGFNSX-UHFFFAOYSA-N 0.000 claims description 4
- 229910052692 Dysprosium Inorganic materials 0.000 claims description 3
- 229910052693 Europium Inorganic materials 0.000 claims description 3
- 229910052689 Holmium Inorganic materials 0.000 claims description 3
- 229910052765 Lutetium Inorganic materials 0.000 claims description 3
- 241001494479 Pecora Species 0.000 claims description 3
- 229910052773 Promethium Inorganic materials 0.000 claims description 3
- 229910052775 Thulium Inorganic materials 0.000 claims description 3
- 229910052769 Ytterbium Inorganic materials 0.000 claims description 3
- KBQHZAAAGSGFKK-UHFFFAOYSA-N dysprosium atom Chemical compound [Dy] KBQHZAAAGSGFKK-UHFFFAOYSA-N 0.000 claims description 3
- OGPBJKLSAFTDLK-UHFFFAOYSA-N europium atom Chemical compound [Eu] OGPBJKLSAFTDLK-UHFFFAOYSA-N 0.000 claims description 3
- KJZYNXUDTRRSPN-UHFFFAOYSA-N holmium atom Chemical compound [Ho] KJZYNXUDTRRSPN-UHFFFAOYSA-N 0.000 claims description 3
- OHSVLFRHMCKCQY-UHFFFAOYSA-N lutetium atom Chemical compound [Lu] OHSVLFRHMCKCQY-UHFFFAOYSA-N 0.000 claims description 3
- VQMWBBYLQSCNPO-UHFFFAOYSA-N promethium atom Chemical compound [Pm] VQMWBBYLQSCNPO-UHFFFAOYSA-N 0.000 claims description 3
- 229910000029 sodium carbonate Inorganic materials 0.000 claims description 3
- NAWDYIZEMPQZHO-UHFFFAOYSA-N ytterbium Chemical compound [Yb] NAWDYIZEMPQZHO-UHFFFAOYSA-N 0.000 claims description 3
- 229940072033 potash Drugs 0.000 claims description 2
- BWHMMNNQKKPAPP-UHFFFAOYSA-L potassium carbonate Substances [K+].[K+].[O-]C([O-])=O BWHMMNNQKKPAPP-UHFFFAOYSA-L 0.000 claims description 2
- 235000015320 potassium carbonate Nutrition 0.000 claims description 2
- 239000000654 additive Substances 0.000 abstract description 7
- 230000000996 additive effect Effects 0.000 abstract description 6
- 239000004459 forage Substances 0.000 abstract description 6
- 238000001914 filtration Methods 0.000 abstract description 5
- 238000001035 drying Methods 0.000 abstract description 3
- 238000010298 pulverizing process Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 238000001179 sorption measurement Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 description 14
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Natural products OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 12
- 238000013270 controlled release Methods 0.000 description 12
- 210000004369 blood Anatomy 0.000 description 10
- 239000008280 blood Substances 0.000 description 10
- 239000002808 molecular sieve Substances 0.000 description 10
- URGAHOPLAPQHLN-UHFFFAOYSA-N sodium aluminosilicate Chemical compound [Na+].[Al+3].[O-][Si]([O-])=O.[O-][Si]([O-])=O URGAHOPLAPQHLN-UHFFFAOYSA-N 0.000 description 10
- 238000012360 testing method Methods 0.000 description 8
- 241000287828 Gallus gallus Species 0.000 description 7
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical group O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 7
- 238000002474 experimental method Methods 0.000 description 7
- ICAKDTKJOYSXGC-UHFFFAOYSA-K lanthanum(iii) chloride Chemical compound Cl[La](Cl)Cl ICAKDTKJOYSXGC-UHFFFAOYSA-K 0.000 description 7
- 239000000047 product Substances 0.000 description 7
- 102000004190 Enzymes Human genes 0.000 description 6
- 108090000790 Enzymes Proteins 0.000 description 6
- 239000011148 porous material Substances 0.000 description 6
- XEEYBQQBJWHFJM-UHFFFAOYSA-N iron Substances [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 5
- 244000144977 poultry Species 0.000 description 5
- 210000002966 serum Anatomy 0.000 description 5
- 108010051696 Growth Hormone Proteins 0.000 description 4
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 4
- 102100038803 Somatotropin Human genes 0.000 description 4
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 4
- 239000000122 growth hormone Substances 0.000 description 4
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 235000013372 meat Nutrition 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 102000006587 Glutathione peroxidase Human genes 0.000 description 3
- 108700016172 Glutathione peroxidases Proteins 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 230000004913 activation Effects 0.000 description 3
- 230000001580 bacterial effect Effects 0.000 description 3
- HSJPMRKMPBAUAU-UHFFFAOYSA-N cerium(3+);trinitrate Chemical compound [Ce+3].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O HSJPMRKMPBAUAU-UHFFFAOYSA-N 0.000 description 3
- 210000004185 liver Anatomy 0.000 description 3
- 230000004060 metabolic process Effects 0.000 description 3
- 210000003205 muscle Anatomy 0.000 description 3
- 210000000496 pancreas Anatomy 0.000 description 3
- 238000011160 research Methods 0.000 description 3
- 235000011121 sodium hydroxide Nutrition 0.000 description 3
- 241000251468 Actinopterygii Species 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 2
- 241000252233 Cyprinus carpio Species 0.000 description 2
- 102000004877 Insulin Human genes 0.000 description 2
- 108090001061 Insulin Proteins 0.000 description 2
- 108091005804 Peptidases Proteins 0.000 description 2
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 description 2
- 241000282887 Suidae Species 0.000 description 2
- 239000012190 activator Substances 0.000 description 2
- JYIBXUUINYLWLR-UHFFFAOYSA-N aluminum;calcium;potassium;silicon;sodium;trihydrate Chemical compound O.O.O.[Na].[Al].[Si].[K].[Ca] JYIBXUUINYLWLR-UHFFFAOYSA-N 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 230000037396 body weight Effects 0.000 description 2
- 210000004556 brain Anatomy 0.000 description 2
- 150000001768 cations Chemical class 0.000 description 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 2
- 229910001603 clinoptilolite Inorganic materials 0.000 description 2
- 150000001875 compounds Chemical class 0.000 description 2
- 229910052802 copper Inorganic materials 0.000 description 2
- 239000010949 copper Substances 0.000 description 2
- FPAFDBFIGPHWGO-UHFFFAOYSA-N dioxosilane;oxomagnesium;hydrate Chemical compound O.[Mg]=O.[Mg]=O.[Mg]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O.O=[Si]=O FPAFDBFIGPHWGO-UHFFFAOYSA-N 0.000 description 2
- 230000002124 endocrine Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 239000003112 inhibitor Substances 0.000 description 2
- 229940125396 insulin Drugs 0.000 description 2
- 229910052742 iron Inorganic materials 0.000 description 2
- 210000003734 kidney Anatomy 0.000 description 2
- 230000037356 lipid metabolism Effects 0.000 description 2
- 229910052751 metal Inorganic materials 0.000 description 2
- 239000002184 metal Substances 0.000 description 2
- 244000005700 microbiome Species 0.000 description 2
- 102000039446 nucleic acids Human genes 0.000 description 2
- 108020004707 nucleic acids Proteins 0.000 description 2
- 150000007523 nucleic acids Chemical class 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- LHBNLZDGIPPZLL-UHFFFAOYSA-K praseodymium(iii) chloride Chemical compound Cl[Pr](Cl)Cl LHBNLZDGIPPZLL-UHFFFAOYSA-K 0.000 description 2
- 230000008569 process Effects 0.000 description 2
- 238000012827 research and development Methods 0.000 description 2
- 229910052711 selenium Inorganic materials 0.000 description 2
- 239000011669 selenium Substances 0.000 description 2
- 229910052710 silicon Inorganic materials 0.000 description 2
- 210000000952 spleen Anatomy 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000002194 synthesizing effect Effects 0.000 description 2
- OBOSXEWFRARQPU-UHFFFAOYSA-N 2-n,2-n-dimethylpyridine-2,5-diamine Chemical compound CN(C)C1=CC=C(N)C=N1 OBOSXEWFRARQPU-UHFFFAOYSA-N 0.000 description 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
- 239000004382 Amylase Substances 0.000 description 1
- 102000013142 Amylases Human genes 0.000 description 1
- 108010065511 Amylases Proteins 0.000 description 1
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Natural products OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 1
- 241000255789 Bombyx mori Species 0.000 description 1
- 102000016938 Catalase Human genes 0.000 description 1
- 108010053835 Catalase Proteins 0.000 description 1
- 229920002101 Chitin Polymers 0.000 description 1
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 1
- 241000238557 Decapoda Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 description 1
- 102100037852 Insulin-like growth factor I Human genes 0.000 description 1
- 102000004882 Lipase Human genes 0.000 description 1
- 108090001060 Lipase Proteins 0.000 description 1
- 239000004367 Lipase Substances 0.000 description 1
- 241000736262 Microbiota Species 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 241000283973 Oryctolagus cuniculus Species 0.000 description 1
- 102000035195 Peptidases Human genes 0.000 description 1
- 239000004365 Protease Substances 0.000 description 1
- 102100037486 Reverse transcriptase/ribonuclease H Human genes 0.000 description 1
- 241000282849 Ruminantia Species 0.000 description 1
- 101000868144 Sus scrofa Somatotropin Proteins 0.000 description 1
- 229930003268 Vitamin C Natural products 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 102000030621 adenylate cyclase Human genes 0.000 description 1
- 108060000200 adenylate cyclase Proteins 0.000 description 1
- 238000012271 agricultural production Methods 0.000 description 1
- 239000003905 agrochemical Substances 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- PNEYBMLMFCGWSK-UHFFFAOYSA-N aluminium oxide Inorganic materials [O-2].[O-2].[O-2].[Al+3].[Al+3] PNEYBMLMFCGWSK-UHFFFAOYSA-N 0.000 description 1
- 229910000323 aluminium silicate Inorganic materials 0.000 description 1
- 150000001412 amines Chemical class 0.000 description 1
- 235000019418 amylase Nutrition 0.000 description 1
- 230000002547 anomalous effect Effects 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
- 238000010241 blood sampling Methods 0.000 description 1
- 239000007853 buffer solution Substances 0.000 description 1
- 150000001720 carbohydrates Chemical class 0.000 description 1
- 230000003197 catalytic effect Effects 0.000 description 1
- VYLVYHXQOHJDJL-UHFFFAOYSA-K cerium trichloride Chemical compound Cl[Ce](Cl)Cl VYLVYHXQOHJDJL-UHFFFAOYSA-K 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 230000001276 controlling effect Effects 0.000 description 1
- 238000009402 cross-breeding Methods 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 230000002255 enzymatic effect Effects 0.000 description 1
- YBYGDBANBWOYIF-UHFFFAOYSA-N erbium(3+);trinitrate Chemical compound [Er+3].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O YBYGDBANBWOYIF-UHFFFAOYSA-N 0.000 description 1
- 229910052675 erionite Inorganic materials 0.000 description 1
- 238000009313 farming Methods 0.000 description 1
- 210000003746 feather Anatomy 0.000 description 1
- 235000021050 feed intake Nutrition 0.000 description 1
- 239000003337 fertilizer Substances 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- MWFSXYMZCVAQCC-UHFFFAOYSA-N gadolinium(iii) nitrate Chemical compound [Gd+3].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O MWFSXYMZCVAQCC-UHFFFAOYSA-N 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 239000003102 growth factor Substances 0.000 description 1
- 230000009931 harmful effect Effects 0.000 description 1
- 150000002402 hexoses Chemical class 0.000 description 1
- 201000001421 hyperglycemia Diseases 0.000 description 1
- 238000005286 illumination Methods 0.000 description 1
- 229910010272 inorganic material Inorganic materials 0.000 description 1
- 239000011147 inorganic material Substances 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 229910052747 lanthanoid Inorganic materials 0.000 description 1
- 150000002602 lanthanoids Chemical class 0.000 description 1
- FYDKNKUEBJQCCN-UHFFFAOYSA-N lanthanum(3+);trinitrate Chemical compound [La+3].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O FYDKNKUEBJQCCN-UHFFFAOYSA-N 0.000 description 1
- 229910001711 laumontite Inorganic materials 0.000 description 1
- 235000019421 lipase Nutrition 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000013335 mesoporous material Substances 0.000 description 1
- 229910021645 metal ion Inorganic materials 0.000 description 1
- 239000002366 mineral element Substances 0.000 description 1
- 230000000116 mitigating effect Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- CFYGEIAZMVFFDE-UHFFFAOYSA-N neodymium(3+);trinitrate Chemical compound [Nd+3].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O CFYGEIAZMVFFDE-UHFFFAOYSA-N 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 235000011118 potassium hydroxide Nutrition 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- YWECOPREQNXXBZ-UHFFFAOYSA-N praseodymium(3+);trinitrate Chemical compound [Pr+3].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O YWECOPREQNXXBZ-UHFFFAOYSA-N 0.000 description 1
- 238000004321 preservation Methods 0.000 description 1
- 235000019833 protease Nutrition 0.000 description 1
- 235000019419 proteases Nutrition 0.000 description 1
- 230000022558 protein metabolic process Effects 0.000 description 1
- 238000003127 radioimmunoassay Methods 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 229920002477 rna polymer Polymers 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 239000010703 silicon Substances 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 235000017550 sodium carbonate Nutrition 0.000 description 1
- 235000013599 spices Nutrition 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-N sulfuric acid Substances OS(O)(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-N 0.000 description 1
- 230000004083 survival effect Effects 0.000 description 1
- YJVUGDIORBKPLC-UHFFFAOYSA-N terbium(3+);trinitrate Chemical compound [Tb+3].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O YJVUGDIORBKPLC-UHFFFAOYSA-N 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000004102 tricarboxylic acid cycle Effects 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 235000019154 vitamin C Nutrition 0.000 description 1
- 239000011718 vitamin C Substances 0.000 description 1
Landscapes
- Fodder In General (AREA)
- Feed For Specific Animals (AREA)
Abstract
A RE-complementing forage additive containing the controlled slow releasing RE is an active RE contained zeolite prepared from RE salt and natural or artificial zeolite through adsorption, ion exchange reaction, filtering, drying and pulverizing.
Description
Technical field
The present invention relates to a kind of feed addictive and preparation and using method of controlled slow release type rare-earth.
Background technology
1. kind of rare earth and products thereof
Rare earth element comprises 15 kinds of elements (atomic number from 57 to 71) and the scandium in the lanthanide series, and totally 17 kinds of elements such as yttrium etc.According to they qualitative some differences, be divided into LREE (scandium, lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium) and heavy rare earth element (gadolinium, terbium, dysprosium, holmium, erbium, yttrium, thulium, ytterbium, lutetium).Wherein cerium accounts for 48%, and lanthanum accounts for 25%, and neodymium accounts for 16%, and samarium accounts for 2%, and praseodymium accounts for 5%, and other 12 kinds of elements only account for 4%.There is abundant rare earth resources in China, and commercial reserves reaches more than 3,600 ten thousand tons, accounts for 80% of world's gross reserves.
China also is that first rare earth is used for farming as commodity, and woods is herded, the country of agricultural productions such as fishing, so the research and development rare earth resources is the focus of basic research such as industrial or agricultural always.In recent years, in animal husbandry, widely applied studies show that the effect that rare earth has remarkable promotion growth of animals or poultry, improves efficiency of feed utilization and increase economic efficiency.Therefore the application of rare earth in animal husbandry become a popular research field, caused many scholars' concern.The rare-earth forage additive that uses comprises inorganic rare earth and organic RE, and the inorganic rare earth major product has nitric acid rare earth, sulfuric acid rare earth, carbonated rare earth, rare earth chloride; The organic RE major product has vitamin C rare earth, citric acid rare earth, amino-acid rare earth and chitin rare earth etc.
2. the biological effect of rare earth
2.1 influence the enzyme system activity
Rare earth is a kind of physiology activator, can stimulate the metabolism of animal body, the growth factor in the activation animal body, is the activator or the inhibitor of many enzymes in the animal body, and it can stablize some enzyme, can improve some enzyme activity, promotes growth of animal.Wedler etc. studies show that the reason of rare earth element raising animal weightening finish may be the activity that their promote animal body endoenzyme, the absorption and the utilization that promote to take the photograph nutritional labeling in the human body.Shao's red magnitude adds 100～500mg/kg rare earth in carp feed, measure part enzymatic activity in liver pancreas, the blood, the result shows, adds an amount of rare earth, can improve carp protease, lipase, amylase and catalase activity, promote of the absorption of fish body nutriment.Zhu Jiaqin etc. studies show that, add the proteinase activity that rare earth improves silkworm body hydrogen peroxide enzyme, midgut tissue, promote hydrogen peroxide decomposes, strengthen protein metabolism; And rare earth element can form complex compound with ATP in the animal body, suppresses the catalytic activity of hexose.Yang Zhiqiang has been studied the influence of nitric acid rare earth to fryer whole blood activity of glutathione peroxidase, the result shows, rare earth has in various degree activation to the animal's whole blood activity of glutathione peroxidase, and proper amount of rare-earth makes the activity of glutathione peroxidase of animal be the stable trend that increases.
2.2 influence nucleic acid metabolism
It is generally acknowledged that many large biological molecules have affinity in rare earth and the body.Studies show that the rare earth of 1mg can be in conjunction with 8.03mgDNA.Rare earth element can be regulated nucleic acid metabolism by the influence to ribonucleic acid polymerase.In addition, rare earth element still is the inhibitor of adenyl cyclase.It is synthetic that LREE can suppress RNA, and heavy rare earth element then has slight activation.
2.3 influence carbohydrate, lipid metabolism
Rare earth element can stimulate the pancreatic excreting insulin, thereby reduces blood sugar concentration, and hyperglycaemia is had mitigation.It can also reduce cholesterol level in the blood, influences tricarboxylic acid cycle, regulates lipid metabolism.
2.4 and the relation between mineral element
Between rare earth element and some element confidential relation is arranged, improving some must the disorderly amount retained in animal body of unit, and the dawn has the effect that replaces indispensable element within the specific limits.Guo Baisheng (1999) points out that rare earth may be by rare earth ion to Ca
2+, Mg
2+, Fe
2+Deng the displacement and the competition of metal ion, thereby influenced the physiological function of some biology enzymes, large biological molecule.The Bao Yumin report adds the absorption that rare earth element can significantly improve P elements in bait, improve its utilization rate.Yang Zhiqiang report adds 150,220 and the rare earth nitrades of 250mg/kg in daily ration of broiler, can improve the content of copper, rare earth, iron, selenium in the fryer blood, and keeps and be higher than control level, and raises the most obvious with the 250mg/kg group.The Zhang Yuehong report adds the accumulation not obviously influence of rare earth to 6 kinds of elements such as copper, manganese, rare earth, iron, selenium, iodine in muscle and the chicken feather in daily grain of chicken, do not find that rare earth have antagonism or synergy to above-mentioned several units.
2.5 rare earth is to action of microorganisms
Rare earth can be regulated bacterial growth, has the difference of regulating and controlling effect, rare earth organic double compound fit form that bacterial growth is had not same-action to bacterial growth.Rare earth can improve the ruminant tumor gastric microbiota, make cud keep stable sour environment, various microorganism ratios reach perfect condition, promote the effective utilization of cud to nutriment, but the rare earth of high dose can destroy the buffer system of cud, makes environment generation ANOMALOUS VARIATIONS in the cud.
3. the problem that in application, exists as feed addictive of rare earth
The rare earth adsorptivity is strong, very easily is adsorbed on the feed surface when mixing with feed, is difficult for mixing with feed.Should be earlier before batching with rare earth and the quantitative abundant mixing of talcum powder, make rare earth be rolled into fine particle, and then send into mixer and mix with feed by talcum powder, also available spraying water-solublely sprays in the feed rare earth is first again.
Mostly present feeding experiment is industry or agriculture rare-earth products if adopting, the animal husbandry special use seldom, the composition difference is very big between various additives, thereby the suitable addition in being difficult to determine to produce.Rare earth element shows the best characteristics of the fastest stage effect of growth to the effect of growth of animals or poultry performance, and its consumption is strict, and every kind of livestock and poultry all have the best dosage of feeding, and are below or above optimal dose, not only somatotrophic advantage can not be shown, but also harmful effect might be produced.Therefore, add rare earth and will determine suitable dose according to livestock and poultry species, sex, age, raising condition, daily ration level and rare-earth products quality.
4. control slow release method
The control slow-released system has selectivity and controllability to release position, speed and the mode of medicine, agricultural chemicals, fertilizer, spices, can realize the target transmission and the control slowly-releasing of object, improve its utilization rate and action effect, the research and the application of control slow-releasing system will bring new technological revolution to relevant industries.The control slow release method is also representing great application prospect and theory significance aspect the research and development of feed addictive, it can promote the high performance and the environmental friendlinessization of product, will provide material and technical guarantee for sustainable development of animal husbandry on new level.
The key of control slow release method is the selection of controlled release carrier.Zeolite is natural existence of a class or the artificial synthetic alumino-silicate with regular pore canal structure, and its chemical composition is: M
2/nAl
2O
3XxSiO
2YH
2O, wherein M represents metal cation, and n is the valence state of metal cation, and x is a silica alumina ratio, and y is the saturation moisture subnumber.Natural zeolite is because of minerogentic condition difference complex structure, and artificial synthetic zeolite molecular sieve is simple in structure, controlled.Constitute the most basic construction unit TO of molecular sieve
4(T=Si, Al or other element) tetrahedron not only can be interconnected to quaternary, cell rings such as hexa-atomic via oxo bridge, can also further be unified into dicyclo, the further connection of these single, double rings just forms panoramic porous zeolite material skeleton structures such as cage shape or different dimension pore canal system.For example eight yuan of oxygen member ring systems comprise erionite, chabasie, α-zeolite, and these zeolites are mesoporous material, comprise the supercage that interconnects in the pore canal system; The ten-ring system claims mesopore zeolite again, comprises natural laumontite and a large amount of artificial synthesizing high-silicon zeolites, contains five yuan of oxygen rings in their skeleton structure, and the pore canal system major part is the single hole road of non-intersection; Double hole channel system zeolite has the internal communication duct of ten binary and perforate of eight yuan of oxygen rings or ten yuan and the eight yuan first perforates of oxygen, and as clinoptilolite, modenite, foresite etc., this class zeolite has mesoporous and two kinds of apertures of micropore.Because zeolite has good biocompatibility and gastrointestinal tract mucous compatibility, the intercommunication pore passage structure and the cage shape space of rule, characteristics such as high surface and huge specific area make it very to be suitable as the control slow-released carrier.
Summary of the invention
The feed addictive and preparation and the using method that the purpose of this invention is to provide a kind of controlled slow release type rare-earth.
The feed addictive of controlled slow release type rare-earth is to adopt trivalent rare earth salt and a kind of zeolite that contains active rare earth natural or that the artificial synthetic zeolite is prepared from through absorption, ion-exchange reactions, and by weight percentage, the content of rare earth in zeolite is 0.5～5%.
The preparation method of the feed addictive of controlled slow release type rare-earth may further comprise the steps:
1) zeolite is ground to greater than 300 orders, adds water and stir, make concentration and be 1%～10% suspension slurry;
2) will contain the rare-earth salts that rare earth content is a zeolite weight 0.5～5%, and slowly add in the suspension slurry of step 1) in stirring down, the pH value that detects and regulate ore pulp is 3.0～6.5, room temperature reaction 4～10 hours;
3) detection step 2) the pH value of slurries is regulated with alkaline solution, and making slurry pH value is 7.0～8.5; Wash 2～5 times, filter or centrifugal dehydration;
4) filter cake of step 3) gained is dried, is crushed to greater than 300 orders, obtain the feed addictive of controlled slow release type rare-earth.
The said zeolite of the present invention can be natural or artificial synthetic zeolite.Synthetic zeolite is the commercial goods or adopts known preparation method's preparation that its technology of preparing is well-known.
The said rare earth of the present invention is to comprise in lanthanum, cerium, praseodymium, neodymium, samarium, promethium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, yttrium, the scandium one or more.Rare-earth salts is single rare earth chloride or nitric acid rare earth, can be two or more rare earth chloride or nitric acid rare earth.Also can be two or more the rare earth chloride or the mixture of nitric acid rare earth.Alkaline solution is that concentration is the aqueous solution of NaOH, potassium hydroxide, sodium carbonate, potash, sodium acid carbonate or the saleratus of 0.5～10moL/L.
Preparation method's slurries dewatering process can be suited measures to local conditions, and selects for use centrifugal or method such as filtration is dewatered.The filter cake of dehydration back gained can use conventional drying plant drying.Controlled slow release type rare-earth feed addictive after the oven dry is block, can select for use conventional disintegrating apparatus to be crushed to granularity greater than 300 orders.
The using method of the feed addictive of controlled slow release type rare-earth is: the feed addictive of the controlled slow release type rare-earth dosage by the 50～500mg/kg that accounts for the feed gross weight (in rare earth) is added in aquatic livestock, ox, sheep, the animal and fowl fodder.
The present invention has the following advantages:
(1) because the carrier zeolite has good biocompatibility and gastrointestinal tract mucous compatibility, the intercommunication pore passage structure and the cage shape space of rule, characteristics such as high surface and huge specific area make it that the rare earth of institute's load is had the control slow releasing function, thereby have improved the absorption rate of rare earth greatly.
(2) the present invention adopts trivalent rare earth salt and natural or artificial synthetic zeolite's absorption, ion-exchange reactions, after filtration, dry, pulverize and make the zeolite that contains active rare earth, this method technological process is simple, low production cost is easy to promotion and implementation.
(3) feed addictive of the present invention is easy to mix with feed, forms even disperse system, and is easy to use.
(4) the prepared controlled slow release type rare-earth of the present invention various animals such as livestock and poultry, ox, sheep, rabbit, fish, shrimp that can be used for feeding have the growth of animal of promotion, improve resistance against diseases and survival rate, raising food utilization efficiency, improve function such as animal product quality.
The specific embodiment
The present invention is further described in conjunction with following example.
Embodiment 1
1) commercially available ZSM-5 type zeolite molecular sieve is ground to 300 orders, adds water and stir, make concentration and be 5% suspension slurry;
2) with lanthanum content be the lanthanum chloride of zeolite weight 0.5% in stirring the suspension slurry that slowly adds step 1) down, the pH value that detects and regulate ore pulp is 4.5, room temperature reaction 6 hours;
3) detection step 2) the pH value of slurries is regulated with the sodium hydrate aqueous solution of 10moL/L, and making slurry pH value is 7.5; Wash filtering means dehydration 3 times;
4) filter cake of step 3) gained is dried, is crushed to 300 orders, obtain controlled release type lanthanum feed addictive, by weight percentage, the content of lanthanum in zeolite is 0.5%.
The influence that the controlled release type lanthanum is residual to pig growth performance, growth hormone secretion and lanthanum
Select the DLY tri-crossbreeding of 72 about 50kg of body weight, be divided into 3 groups (every group of 3 repetitions, each repeats 8, male and female half and half) by the feeding experiment requirement: 0, the controlled release type lanthanum of the lanthanum chloride of 50mg/kg lanthanum, 50mg/kg lanthanum.Test pig group feeding powder is freely drunk water, prerun 7d, and normal test schedules to last 60d.After the off-test, stop feeding 24h, weigh.Calculate test pig feed intake, daily gain and material anharmonic ratio.
Continuously blood sampling test: after feeding experiment finishes, select 4 of test pig (male and female half and half) from every group, totally 12, carry out ear vein and take a blood sample continuously, 15min 1 time, the 5mL that at every turn takes a blood sample continues 3h.The blood sample of will taking a blood sample continuously leaves standstill in different test tubes successively, separates out serum ,-80 ℃ of preservations.Adopt measured by radioimmunoassay growth hormone (GH).
Butcher sampling: feeding experiment selects 6 pigs to butcher from every group after finishing, and takes longissimus dorsi muscle, liver,kidney,spleen, pancreas, brain sample, preserves lanthanum residual quantity to be analyzed for-30 ℃.
The result shows:
(1) adds the controlled release type lanthanum of 50mg/kg lanthanum and the lanthanum chloride of 50mg/kg lanthanum and make daily gain in pigs improve 11.2% (P＜0.05) and 7.3% (P＞0.05) respectively, make feed efficiency improve 7.4% (P＜0.05) and 4.2% (P＞0.05) respectively;
(2) the controlled release type lanthanum of interpolation 50mg/kg lanthanum makes pig growth hormone of serum peak intensity, baseline values, aggregate level improve 108.2% (P＜0.05), 91.2% (P＜0.05) and 87.6% (P＜0.05) respectively; Though add the lanthanum chloride of 50mg/kg lanthanum the trend that improves growth hormone of serum peak intensity, baseline values, aggregate level is arranged, but difference not significantly (P＞0.05).
(3) the controlled release type lanthanum that adds the lanthanum chloride of 50mg/kg lanthanum and 50mg/kg lanthanum is to longissimus dorsi muscle, liver,kidney,spleen, pancreas, brain lanthanum content all do not make significant difference (P＞0.05).
Embodiment 2
The preparation: according to " modification of mesopore molecular sieve MCM-41 and sign under the temperate condition " (Zheng Shan, high Lian, Guo Jingkun. Journal of Inorganic Materials, 2000,15 (5): method 844-848) prepares mesopore molecular sieve MCM-41.
1) the mesopore molecular sieve MCM-41 that obtains in the preliminary step is ground to 300 orders, adds water and stir, make concentration and be 1% suspension slurry;
2) with cerium content be the cerous nitrate of MCM-41 weight 1.5% in stirring the suspension slurry that slowly adds step 1) down, the pH value that detects and regulate ore pulp is 6.5, room temperature reaction 10 hours;
3) detection step 2) the pH value of slurries is regulated with the potassium hydroxide aqueous solution of 5moL/L, and making slurry pH value is 8.5; Wash centrifugal dehydration 5 times;
4) filter cake of step 3) gained is dried, is crushed to 400 orders, obtain controlled release type and mend the cerium feed addictive, by weight percentage, the content of cerium in MCM-41 is 1.5%.
Embodiment 3
1) clinoptilolite that will originate from Jinyun county, Zhejiang province is ground to 500 orders, adds water and stirs, and makes concentration and be 10% suspension slurry;
2) be that the lanthanum nitrate of zeolite weight 1%, cerium chloride and the praseodymium content that cerium content is zeolite weight 1% are the praseodymium chloride of zeolite weight 0.5% with lanthanum content, slowly add in the suspension slurry of step 1) in stirring down, the pH value that detects and regulate ore pulp is 3.0, room temperature reaction 4 hours;
3) detection step 2) the pH value of slurries is regulated with the aqueous sodium carbonate of 0.5moL/L, and making slurry pH value is 7.0; Wash filtering means dehydration 4 times;
4) filter cake of step 3) gained is dried, is crushed to 600 orders, obtain controlled release type and mend rare-earth forage additive, by weight percentage, the content of rare earth (lanthanum, cerium and praseodymium) in zeolite is 2.5%.
Controlled slow release type rare-earth is to growth of meat chicken and endocrine influence:
Is subjects with the AA commodity for mixing chick, has studied controlled slow release type rare-earth to growth of meat chicken and endocrine influence.Meat chick 240 plumages of 1 age in days that the selective body heavy phase is near are divided into 3 groups (establish 4 repetitions for every group, each repeats 20 plumages) at random, are respectively blank, 100mg/kg citric acid rare earth and 100mg/kg controlled slow release type rare-earth.Under the condition of free choice feeding, drinking-water and illumination in 24 hours, carry out 56 days feeding experiment by a definite date.After feeding experiment finished, every group was selected close test chicken 16 plumages of body weight (male and female half and half), totally 48 plumages, and the not feed that feeds water, fasting 12 hours is butchered, and takes blood serum sample.
Feeding experiment result shows: compare with control group, add controlled slow release type rare-earth and citric acid rare earth and make daily gain improve 12.5% (P＜0.05) and 7.2% (P＜0.05) respectively; Controlled slow release type rare-earth makes material anharmonic ratio 8.5% (P＜0.05) that descended; And the citric acid rare earth does not have obvious influence to the material anharmonic ratio.
Citric acid rare earth and controlled slow release type rare-earth make T in the serum respectively
4Activity has improved 28.7% (P＜0.05) and 68.3% (P＜0.01).Make controlled slow release type rare-earth insulin and insulin-like growth factor I level have improved 31.8% (P＜0.05) and 39.4% (P＜0.01) respectively.
The prompting of this result of study: the action effect of controlled slow release type rare-earth on the raising growth of meat chicken slightly is better than the citric acid rare earth with dosage.
Embodiment 4
1) commercially available 4A type zeolite molecular sieve is ground to 400 orders, adds water and stir, make concentration and be 8% suspension slurry;
2) be that the terbium nitrate and the yttrium content of zeolite weight 1% is the yttrium chloride of zeolite weight 1% with terbium content, in stirring the suspension slurry that slowly adds step 1) down, the pH value that detects and regulate ore pulp is 4.0, room temperature reaction 6 hours;
3) detection step 2) the pH value of slurries is regulated with the wet chemical of 2moL/L, and making slurry pH value is 7.5; Wash centrifugal dehydration 2 times;
4) filter cake of step 3) gained is dried, is crushed to 500 orders, obtain controlled release type and mend rare-earth forage additive, by weight percentage, the content of rare earth (terbium and yttrium) in zeolite is 2.0%.
Embodiment 5
1) epidesmine that will originate from Guangxi is ground to 600 orders, adds water and stirs, and makes concentration and be 4% suspension slurry;
2) be that the lanthanum chloride of zeolite weight 1%, the cerous nitrate that cerium content is zeolite weight 1%, praseodymium chloride and the neodymium content that praseodymium content is zeolite weight 0.5% are the neodymium nitrate of zeolite weight 0.5% with lanthanum content, slowly add in the suspension slurry of step 1) in stirring down, the pH value that detects and regulate ore pulp is 4.5, room temperature reaction 10 hours;
3) detection step 2) the pH value of slurries is regulated with the sodium hydrate aqueous solution of 6moL/L, and making slurry pH value is 7.0; Wash centrifugal dehydration 4 times;
4) filter cake of step 3) gained is dried, is crushed to 600 orders, obtain controlled release type and mend rare-earth forage additive, by weight percentage, the content of rare earth (lanthanum, cerium, praseodymium, neodymium) in zeolite is 3%.
Embodiment 6
The preparation: according to " the ZSM-5 zeolite molecular sieve of non-amine method synthesizing high-silicon aluminum ratio and high-crystallinity " (Xiang Shouhe, Liu Shuquan, Wang Jingzhong, Li He is noisy etc. national inventing patent Granted publication 1046922C) method prepare the ZSM-5 zeolite molecular sieve.
1) the ZSM-5 zeolite molecular sieve that obtains in the preliminary step is ground to 300 orders, adds water and stir, make concentration and be 6% suspension slurry;
2) be that the lanthanum chloride of zeolite weight 1%, the cerous nitrate that cerium content is zeolite weight 1.5%, the praseodymium nitrate that praseodymium content is zeolite weight 1%, erbium nitrate and the gadolinium concentrations that erbium content is zeolite weight 1% are the gadolinium nitrate of zeolite weight 0.5% with lanthanum content, slowly add in the suspension slurry of step 1) in stirring down, the pH value that detects and regulate ore pulp is 4.5, room temperature reaction 4 hours;
3) detection step 2) the pH value of slurries is regulated with the potassium hydroxide aqueous solution of 6moL/L, and making slurry pH value is 8.0; Wash centrifugal dehydration 4 times;
4) filter cake of step 3) gained is dried, is crushed to 400 orders, obtain controlled release type and mend rare-earth forage additive, by weight percentage, the content of rare earth (lanthanum, cerium, praseodymium, erbium, gadolinium) in zeolite is 5%.
Claims (8)
1. the feed addictive of a controlled slow release type rare-earth, it is characterized in that it is to adopt trivalent rare earth salt and a kind of zeolite that contains active rare earth natural or that the artificial synthetic zeolite is prepared from through absorption, ion-exchange reactions, by weight percentage, the content of rare earth in zeolite is 0.5～5%.
2. the feed addictive of a kind of controlled slow release type rare-earth according to claim 1 is characterized in that, said rare earth is to comprise in lanthanum, cerium, praseodymium, neodymium, samarium, promethium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium, yttrium, the scandium one or more.
3. the feed addictive of a kind of controlled slow release type rare-earth according to claim 1 is characterized in that, said rare-earth salts is single rare earth chloride or nitric acid rare earth.
4. the feed addictive of a kind of controlled slow release type rare-earth according to claim 1 is characterized in that, said rare-earth salts is two or more rare earth chloride or nitric acid rare earth.
5. the feed addictive of a kind of controlled slow release type rare-earth according to claim 1 is characterized in that, said rare-earth salts is two or more the rare earth chloride or the mixture of nitric acid rare earth.
6. the preparation method of the feed addictive of an a kind of controlled slow release type rare-earth as claimed in claim 1 is characterized in that the step of method is as follows:
1) zeolite is ground to greater than 300 orders, adds water and stir, make concentration and be 1%～10% suspension slurry;
2) will contain the trivalent rare earth salt that rare earth content is a zeolite weight 0.5～5%, and slowly add in the suspension slurry of step 1) in stirring down, the pH value that detects and regulate ore pulp is 3.0～6.5, room temperature reaction 4～10 hours;
3) detection step 2) the pH value of slurries is regulated with alkaline solution, and making slurry pH value is 7.0～8.5; Wash 2～5 times, filter or centrifugal dehydration;
4) filter cake of step 3) gained is dried, is crushed to greater than 300 orders, obtain the controlled slow release type rare-earth feed addictive.
7. the preparation method of the feed addictive of a kind of controlled slow release type rare-earth according to claim 6 is characterized in that described alkaline solution is that concentration is the aqueous solution of NaOH, potassium hydroxide, sodium carbonate, potash, sodium acid carbonate or the saleratus of 0.5～10moL/L.
8. an a kind of using method of feed addictive of controlled slow release type rare-earth according to claim 1 is characterized in that the feed addictive of controlled slow release type rare-earth is added in aquatic livestock, ox, sheep, the animal and fowl fodder in the dosage of rare earth by the 50～500mg/kg that accounts for the feed gross weight.
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106490375A (en) * | 2016-10-27 | 2017-03-15 | 赵林 | A kind of calf special feed |
| CN110169497A (en) * | 2019-07-04 | 2019-08-27 | 湖南师范大学 | It is a kind of to adjust the feed addictive and its application that livestock and poultry enterocyte falls off |
| CN113317394A (en) * | 2021-06-02 | 2021-08-31 | 湖南农业大学 | Preparation method of rare earth modified attapulgite feed additive |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| JPH01126393A (en) * | 1986-11-10 | 1989-05-18 | Tomoji Tanaka | Soil conditioner and feed additive |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106490375A (en) * | 2016-10-27 | 2017-03-15 | 赵林 | A kind of calf special feed |
| CN110169497A (en) * | 2019-07-04 | 2019-08-27 | 湖南师范大学 | It is a kind of to adjust the feed addictive and its application that livestock and poultry enterocyte falls off |
| CN113317394A (en) * | 2021-06-02 | 2021-08-31 | 湖南农业大学 | Preparation method of rare earth modified attapulgite feed additive |
| CN113317394B (en) * | 2021-06-02 | 2024-07-09 | 湖南农业大学 | Preparation method of rare earth modified attapulgite feed additive |
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