CN1813688A - Wound bandage and plaster - Google Patents

Wound bandage and plaster Download PDF

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Publication number
CN1813688A
CN1813688A CN 200510134587 CN200510134587A CN1813688A CN 1813688 A CN1813688 A CN 1813688A CN 200510134587 CN200510134587 CN 200510134587 CN 200510134587 A CN200510134587 A CN 200510134587A CN 1813688 A CN1813688 A CN 1813688A
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China
Prior art keywords
nexine
adhesive bandage
plaster
poly tetrafluoroethylene
microporous poly
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CN 200510134587
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Chinese (zh)
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CN100493612C (en
Inventor
李强
李耸
江伟
黄西甫
黄宽
李新宇
葛飞
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李强
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Priority to CNB2005101345876A priority Critical patent/CN100493612C/en
Publication of CN1813688A publication Critical patent/CN1813688A/en
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Publication of CN100493612C publication Critical patent/CN100493612C/en
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Abstract

The present invention relates to an adhesive plaster for treating wound. It is characterized by that it includes two layers of inner layer and outer layer, the described inner layer and outer layer are adhered into one whole body, its inner layer is made up by using fabric material containing natural marine high-polymer chitoamine fibre and its outer layer is made up by using microporous teflon film material. Said adhesive plaster has the functions of resisting bacteria, relieving inflammation, arresting bleeding, promoting wound healing and promoting tissue growth, etc.

Description

Adhesive bandage and plaster paste
Technical field
The present invention relates to adhesive bandage and plaster and paste, particularly not only can waterproof but also adhesive bandage and plaster with air permeability and good paste.
Background technology
General adhesive bandage and plaster paste can not waterproof, does not have breathability, seals on skin extremely uncomfortable, particularly occur in when waiting the position that often gets wet on hand at wound, must often change adhesive bandage, or seal to such an extent that wound turns white all around, wound can not be healed for a long time.
Introduce the used raw-material background information of the present invention below.Chitin fiber is from the carapace of shrimp, Eriocheir sinensis and shell-fish, and annual ocean is produced the carapace amount and reached 1,000,000,000 tons, is only second to cellulose in the output of natural polymer.Chitin is a kind of natural polysaccharide material, because it has crystal structure and more hydrogen bond preferably, therefore, its solubility property is very poor.To become its solubility property of chitosan (also claiming chitosan) better than chitin through deacetylated for carapace.Purified chitin or chitosan are dissolved in suitable solvent, are made for chitin fiber or chitosan fiber by wet spinning.Because chitin or chitosan have excellent biological compatibility and adaptability, and have functions such as antibiotic, antibacterial, antiinflammatory, hemostasis, analgesia and the growth of promotion when injected organism tissue, can promote wound healing, therefore be acknowledged as the ideal material of protection wound.
The antifungal mechanism of carapace fiber: (1) macromole chitin (chitosan) is adsorbed on cell surface by the interaction of positive and negative charge, destroys the cell wall original structure, causes the confusion of cellular metabolism, thereby plays the effect of bacteriostasis and sterilization.(2) micromolecule chitin (chitosan), it has anionic biomacromolecule generation " flocculation " effect by penetrating in the cell, upset the normal biological function of cell, changes nucleic acid metabolism, the biosynthesis of blocking dna, thereby the breeding of inhibition antibacterial.(3) chitin can be induced microorganisms chitin enzyme, impels cell to decompose and cell growth inhibiting.Chitin is as the fibre fractionation in the lower animal, have the biological function of cellulose in collagen in the higher mammal tissue and the higher plant fiber concurrently, so biological nature is very excellent, and its principal character is: (1) good biocompatibility.Chitin and derivant thereof are the natural macromolecular materials that has no side effect, and its chemical property and biological property and tissue are close, and therefore, there are not exclusive problem in its goods and human body.(2) biological activity excellence.Chitin and derivant thereof show multiple biological activity because of contained complicated spatial structure itself, and that its goods have is antibiotic, antibacterial, reduce serum and cholesterol level, the inhibition fibroblast growth, directly suppress tumor cell and promote epithelial cell growth, promote effects such as humoral immunization and cellular immunization.Chitin fiber fabric CN1313416 in the early stage patent of applicant is existing open.
The polytetrafluoroethylmaterial material of all size is various apertures for example, all thickness, its total advantage be have good Waterproof Breathable, Radix Saposhnikoviae oxygen flow, warming, intercept multiple functions such as antibacterial, virus, microgranule, micronic dust filtration, antiseep, no water droplet, use very extensive.
Summary of the invention
The object of the present invention is to provide a kind of adhesive bandage and plaster to paste, this adhesive bandage not only can waterproof, and has superpower saturating wet, ventilative a, oxygen permeability, not only can prevent because the wound infection that skin gets wet and causes, and can very strong bacteria resistance function be arranged to escherichia coli, staphylococcus aureus, the Candida albicans of harmful to human, bacteriostasis rate can reach more than 93%.
Adhesive bandage of the present invention comprises nexine and outer two-layer at least, and described nexine and outer the stickup are integral, and it is characterized in that described nexine is made of the textile material that contains natural marine high polymer chitosan fiber; Described skin is made of microporous poly tetrafluoroethylene material (ePTFE).Politef has waterproofing and moisture-penetration performances, and when the micro-pore diameter of politef membrane material was chosen in 0.1~0.5 μ m, this diameter was 1/5000~1/2000 of a drop diameter, is 700 times of water vapour molecule.Because the micro-pore diameter of ePTFE membrane material is 1/5000~1/2000 of a drop diameter, so the moisture of outside can not infiltrate from skin.Simultaneously, because the micro-pore diameter of ePTFE membrane material is 700 times of hydrone, antiperspirant steam is unimpeded to appear so can make, and does not accumulate between body surface and the fabric, and the people is felt comfortably cool, and does not produce stuffy sensation.Adhesive material is general hot melt moisturecuring melten gel, and for example response type polyurethane PUR is not particularly limited for the condition of pasting.
The feature of adhesive bandage of the present invention is that also the thickness of described microporous poly tetrafluoroethylene material is 20~70 μ m.
The feature of adhesive bandage of the present invention is that also the thickness of described microporous poly tetrafluoroethylene material is 30~50 μ m.
The feature of adhesive bandage of the present invention is that also the micro-pore diameter of described microporous poly tetrafluoroethylene material is chosen as 0.1-0.5 μ m.
Plaster of the present invention is labelled to and comprises nexine and outer two-layer less, and described nexine and outer the stickup are integral, and it is characterized in that described nexine is made of the textile material that contains natural marine high polymer chitosan fiber; Described skin is made of microporous poly tetrafluoroethylene material (ePTFE), in addition, and the plaster of the present invention medicament layer that is sticked.Because adhesive bandage of the present invention is established medicament layer, this medicament layer can be the medicine of blood circulation promoting, treatment rheumatism, intervertebral disk hernia, alleviation myalgia, so not only can be used for treating partial scuffing, and can be used for alleviating because the misery that rheumatism, intervertebral disk hernia, myalgia etc. are brought to patient.
Adhesive bandage of the present invention not only can waterproof, and has superpower saturating wet, ventilative a, oxygen permeability, instrument can not prevent because the wound infection that skin gets wet and causes, promote wound healing, and can very strong bacteria resistance function be arranged to escherichia coli, staphylococcus aureus, the Candida albicans of harmful to human, bacteriostasis rate can reach more than 93%.
Description of drawings
Fig. 1 is the sectional structure chart of adhesive bandage of the present invention.
Fig. 2 is the sectional structure chart of another embodiment of adhesive bandage of the present invention.
Fig. 3 is the sectional structure chart that plaster of the present invention pastes.
Fig. 4 is the functional schematic that adhesive bandage of the present invention and plaster paste.
The specific embodiment
Followingly the specific embodiment that adhesive bandage of the present invention and plaster paste is elaborated with reference to accompanying drawing.
Fig. 1 is the structural representation of adhesive bandage of the present invention.Adhesive bandage of the present invention comprise at least outer 1 and nexine 2 two-layer, this skin 1 and nexine 2 are pasted and are integral, wherein, nexine 2 is made of the textile material that contains natural marine high polymer chitosan fiber (hereinafter to be referred as the marine organisms fibrous material); Outer 1 is made of microporous poly tetrafluoroethylene material (to call the ePTFE membrane material in the following text).The thickness of ePTFE membrane material is 20~70 μ m.3 is the top layer, and this top layer can be decorative layer, also can be protective layer, and the ePTFE membrane material of protection inboard is not impaired.The textile material that contains natural marine high polymer chitosan fiber is disclosed among the open source literature CN1313416 narration.Adhesive material is general hot melt moisturecuring melten gel, and for example response type polyurethane PUR is not particularly limited for the condition of pasting.
Fig. 2 is the sectional structure chart of another embodiment of adhesive bandage of the present invention.Also be provided with medicament layer 4 in the nexine of adhesive bandage of the present invention, this medicament layer can be the medicament of hemostasis, antiinflammatory.
Fig. 3 is the sectional structure chart that plaster of the present invention pastes.Plaster of the present invention is labelled to and comprises that less outer 1 ' is two-layer with nexine 2 ', and this skin 1 ' and nexine 2 ' are pasted and be integral, and wherein, nexine 2 ' is made of the textile material that contains natural marine high polymer chitosan fiber (hereinafter to be referred as the marine organisms fibrous material); Outer 1 ' by microporous poly tetrafluoroethylene material (to call the ePTFE membrane material in the following text) formation, in addition, also is provided with medicament layer 4 ' in nexine 2 ', and this medicament layer can be the medicine of blood circulation promoting, treatment rheumatism, intervertebral disk hernia, alleviation myalgia.The thickness of ePTFE membrane material is 20~70 μ m.The textile material that contains natural marine high polymer chitosan fiber is disclosed among the open source literature CN1313416 narration.Adhesive material is general hot melt moisturecuring melten gel, and for example response type polyurethane PUR is not particularly limited for the condition of pasting.
Below action principle that adhesive bandage of the present invention and plaster are pasted describe.
Fig. 4 is the functional schematic that adhesive bandage of the present invention and plaster paste.The nexine 2, outer 1 that antiperspirant gas in arrow 5 expression adhesive bandages and plaster paste can pass adhesive bandage and plaster subsides is dispersed in the air.Arrow 6 expression water droplets are intercepted the inside that externally can not enter adhesive bandage by outer 1.
Because the skin 1 of adhesive bandage is the microporous poly tetrafluoroethylene material, thickness 20~70 μ m of membrane material, the membrane material surface is covered with fibril shape micropore, the cross section of membrane material is a kind of web frame, very complicated structures such as netted connection, hole edge cover, duct bending are arranged on the three dimensional structure in hole, by a plurality of micropores form a passage, a micropore that has links to each other with a plurality of passages.EPTFE membrane material micro-pore diameter excursion is 1/5000~1/2000 of a drop diameter at 0.1~0.5 μ m, is 700 times of water vapour molecule.Because the micro-pore diameter of ePTFE membrane material is 1/5000~1/2000 of a drop diameter, so the water of outside can not infiltrate from skin.
In addition, because the micro-pore diameter of ePTFE membrane material is 700 times of hydrone, antiperspirant steam is unimpeded to appear so can make, and does not accumulate between body surface and the fabric, and the people is felt comfortably cool.
Adhesive bandage of the present invention and plaster paste not only can waterproof, and has superpower saturating wet a, breathability, not only can prevent because the wound infection that skin gets wet and causes, promote wound healing, and can very strong bacteria resistance function be arranged to escherichia coli, staphylococcus aureus, the Candida albicans of harmful to human, bacteriostasis rate can reach more than 93%.

Claims (9)

1, a kind of adhesive bandage is characterized in that, comprises nexine and outer two-layer at least, and described nexine and outer the stickup are integral, and its nexine is made of the textile material that contains natural marine high polymer chitosan fiber; Its skin is made of the microporous poly tetrafluoroethylene material.
2, adhesive bandage as claimed in claim 1 is characterised in that, the thickness of microporous poly tetrafluoroethylene material is 20~70 μ m.
3, adhesive bandage as claimed in claim 1 is characterised in that, the thickness of microporous poly tetrafluoroethylene material is 30~50 μ m.
4, as any described adhesive bandage of claim 1-3, it is characterized in that the micro-pore diameter of described microporous poly tetrafluoroethylene material is chosen as 0.1-0.5 μ m.
5, as any described adhesive bandage of claim 1-3, it is characterized in that, establish medicament layer in the inside of described nexine.
6, a kind of plaster pastes, and it is characterized in that, comprises nexine and outer two-layer at least, and described nexine and outer the stickup are integral, and its nexine is made of the textile material that contains natural marine high polymer chitosan fiber; Its skin is made of the microporous poly tetrafluoroethylene material;
In addition, establish medicament layer in the inside of described nexine.
7, described plaster as claimed in claim 6 pastes, and it is characterized in that the thickness of described microporous poly tetrafluoroethylene material is 20~70 μ m.
8, plaster as claimed in claim 1 pastes, and is characterised in that the thickness of described microporous poly tetrafluoroethylene material is 30~50 μ m.
9, any described plaster as claim 6~8 pastes, and it is characterized in that the micro-pore diameter of described microporous poly tetrafluoroethylene material is chosen as 0.1-0.5 μ m.
CNB2005101345876A 2005-12-22 2005-12-22 Wound bandage and plaster Expired - Fee Related CN100493612C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CNB2005101345876A CN100493612C (en) 2005-12-22 2005-12-22 Wound bandage and plaster

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CNB2005101345876A CN100493612C (en) 2005-12-22 2005-12-22 Wound bandage and plaster

Publications (2)

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CN1813688A true CN1813688A (en) 2006-08-09
CN100493612C CN100493612C (en) 2009-06-03

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Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1270011A (en) * 1999-12-06 2000-10-18 周松亮 Water-proof air-permeable plaster for curing wound and its preparing process
EP1284137B1 (en) * 2000-05-26 2010-12-01 TAKADA, Kanji Nonoral preparation having three-layer structure
CN2689944Y (en) * 2003-12-07 2005-04-06 国家海洋局杭州水处理技术开发中心 Chitosan medical film wound plaster
CN1216593C (en) * 2004-04-13 2005-08-31 李宇光 Liquid wound plaster and its preparing method

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Granted publication date: 20090603

Termination date: 20131222