CN1800201A - Polymyxin E separation preparation method - Google Patents
Polymyxin E separation preparation method Download PDFInfo
- Publication number
- CN1800201A CN1800201A CN 200510122187 CN200510122187A CN1800201A CN 1800201 A CN1800201 A CN 1800201A CN 200510122187 CN200510122187 CN 200510122187 CN 200510122187 A CN200510122187 A CN 200510122187A CN 1800201 A CN1800201 A CN 1800201A
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- Prior art keywords
- polymyxin
- foam
- liquid
- fermented liquid
- temperature
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
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Claims (4)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CNB2005101221873A CN100347188C (en) | 2005-12-06 | 2005-12-06 | Polymyxin E separation preparation method |
Applications Claiming Priority (1)
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CNB2005101221873A CN100347188C (en) | 2005-12-06 | 2005-12-06 | Polymyxin E separation preparation method |
Publications (2)
Publication Number | Publication Date |
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CN1800201A true CN1800201A (en) | 2006-07-12 |
CN100347188C CN100347188C (en) | 2007-11-07 |
Family
ID=36810445
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CNB2005101221873A Expired - Fee Related CN100347188C (en) | 2005-12-06 | 2005-12-06 | Polymyxin E separation preparation method |
Country Status (1)
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CN (1) | CN100347188C (en) |
Cited By (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010058427A2 (en) | 2008-11-24 | 2010-05-27 | Reliance Life Sciences Pvt. Ltd. | Process for production and purification of polymyxin b sulfate |
CN101974075A (en) * | 2010-10-12 | 2011-02-16 | 山东鲁抗医药股份有限公司 | Method for extracting polymyxin B and E from fermentation technique culture |
CN102190711A (en) * | 2010-01-22 | 2011-09-21 | 上海医药工业研究院 | Polymyxin E composition and preparation method and application thereof |
CN102250220A (en) * | 2011-07-11 | 2011-11-23 | 浙江升华拜克生物股份有限公司 | Preparation method of colistin sulphate |
CN102718842A (en) * | 2012-07-16 | 2012-10-10 | 河北圣雪大成制药有限责任公司 | Process for extracting colistin sulfate through precipitation method |
CN104327167A (en) * | 2014-09-28 | 2015-02-04 | 河北圣雪大成制药有限责任公司 | Technology for extracting polymyxin B through precipitation method |
CN105543314A (en) * | 2016-03-06 | 2016-05-04 | 河北工业大学 | Method for producing polymyxin E through fermentation and foam separation coupling |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102250219B (en) * | 2011-07-11 | 2013-04-17 | 浙江升华拜克生物股份有限公司 | Method for preparing colistine sulfate B |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3969336A (en) * | 1974-05-22 | 1976-07-13 | Abbott Laboratories | Method of separating and recovering soluble proteins from protein containing solutions employing foam fractionation |
-
2005
- 2005-12-06 CN CNB2005101221873A patent/CN100347188C/en not_active Expired - Fee Related
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010058427A2 (en) | 2008-11-24 | 2010-05-27 | Reliance Life Sciences Pvt. Ltd. | Process for production and purification of polymyxin b sulfate |
CN102190711A (en) * | 2010-01-22 | 2011-09-21 | 上海医药工业研究院 | Polymyxin E composition and preparation method and application thereof |
CN102190710A (en) * | 2010-01-22 | 2011-09-21 | 上海医药工业研究院 | Polymyxin E2 composition, and preparation method and application thereof |
CN101974075A (en) * | 2010-10-12 | 2011-02-16 | 山东鲁抗医药股份有限公司 | Method for extracting polymyxin B and E from fermentation technique culture |
CN102250220A (en) * | 2011-07-11 | 2011-11-23 | 浙江升华拜克生物股份有限公司 | Preparation method of colistin sulphate |
CN102250220B (en) * | 2011-07-11 | 2013-02-13 | 浙江升华拜克生物股份有限公司 | Preparation method of colistin sulphate |
CN102718842A (en) * | 2012-07-16 | 2012-10-10 | 河北圣雪大成制药有限责任公司 | Process for extracting colistin sulfate through precipitation method |
CN104327167A (en) * | 2014-09-28 | 2015-02-04 | 河北圣雪大成制药有限责任公司 | Technology for extracting polymyxin B through precipitation method |
CN105543314A (en) * | 2016-03-06 | 2016-05-04 | 河北工业大学 | Method for producing polymyxin E through fermentation and foam separation coupling |
Also Published As
Publication number | Publication date |
---|---|
CN100347188C (en) | 2007-11-07 |
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Legal Events
Date | Code | Title | Description |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Shijiazhuang No.4 Pharmaceutical Co., Ltd. Assignor: Hebei University of Technology Contract fulfillment period: 2009.7.28 to 2012.7.28 contract change Contract record no.: 2009120000185 Denomination of invention: Polymyxin E separation preparation method Granted publication date: 20071107 License type: Exclusive license Record date: 2009.8.21 |
|
LIC | Patent licence contract for exploitation submitted for record |
Free format text: EXCLUSIVE LICENSE; TIME LIMIT OF IMPLEMENTING CONTACT: 2009.7.28 TO 2012.7.28; CHANGE OF CONTRACT Name of requester: SHIJIAZHUANG SIYAO CO., LTD. Effective date: 20090821 |
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CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20071107 Termination date: 20151206 |
|
EXPY | Termination of patent right or utility model |