CN1788761A - Body-building weight-reducing capsule and its preparation process - Google Patents
Body-building weight-reducing capsule and its preparation process Download PDFInfo
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- CN1788761A CN1788761A CNA2004100470713A CN200410047071A CN1788761A CN 1788761 A CN1788761 A CN 1788761A CN A2004100470713 A CNA2004100470713 A CN A2004100470713A CN 200410047071 A CN200410047071 A CN 200410047071A CN 1788761 A CN1788761 A CN 1788761A
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- herb gynostemmae
- gynostemmae pentaphylli
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Abstract
The present invention discloses beautifying and slimming capsule and its preparation process. The capsule contains the active components of the medicine materials, including gynostemma pentaphylla extractum 8-10 weight portions, levo-kreotoxin 5-6 weight portions, abalone shell 4-5 weight portions, immature bitter orange 5-6 weight portions,magnolia bark 4-5 weight portions, hemp seed 4-5 weight portions and honeysuckle 4-5 weight portions. Its preparation process includes extracting gynostemma pentaphylla to obtain extractum, mixing with fine powder of the other components, sterilizing and encapsulating. Clinical application shows that the capsule of the present invention has obvious weight reducing effect.
Description
Technical field
The present invention relates to a kind of fat-reducing Chinese patent medicine preparation and preparation method thereof, particularly vigorous and graceful weight reducing capsule and preparation method thereof.
Background technology
At present diet tea, diet food, the appetrol of selling on the market have a variety of, as being the Kang Er longevity slimming capsule of primary raw material with Herb Gynostemmae Pentaphylli, the Cortex Eucommiae, Ganoderma, Cordyceps, Poria; With Fructus Crataegi, green tea, Citrus aurantium L. var. amara Engl., Folium Nelumbinis, gypenoside is the strong cypress hall slimming capsule of primary raw material; With Fructus Crataegi, Fructus Lycii, Poria, Rhizoma Alismatis, Herb Gynostemmae Pentaphylli, Semen Cassiae, Semen sojae atricolor is board diet teas on the five of primary raw material; With L-carnitine and tea polyphenols is the excellent board slimming capsule of primary raw material; With soybean polypeptide, L-carnitine-L-tartrate, vitamin B1, vitamin B2 is the profit bodyguard board Mai Tai sheet of primary raw material; With Sargassum, Fructus Cannabis, the Rhizoma Atractylodis Macrocephalae, Radix Glycyrrhizae, Semen Cassiae, Radix Ginseng, the Radix Paeoniae Alba, Rhizoma Zingiberis, Fructus Aurantii is the digital board slimming capsule of primary raw material; With Fructus Crataegi, Folium Nelumbinis, Semen Cassiae, Flos Lonicerae, Semen Armeniacae Amarum, green tea is the capital diet tea of primary raw material; With Folium Nelumbinis, Endothelium Corneum Gigeriae Galli, Fructus Lycii, Radix Ginseng is the thin precious draft capsule of primary raw material; With Lentinus Edodes, Fructus Crataegi, wheat flour, black tea, Rhizomadioscoreae, Thallus Laminariae (Thallus Eckloniae) powder, Rhizoma amorphophalli, spirulina, L-carnitine be primary raw material to repair appearance happy; With Semen Cassiae, Fructus Cannabis, Folium Nelumbinis, Fructus Crataegi is the blue or green slender waist skin care of the willow capsule of primary raw material.Also have some Chinese patent application also to disclose the technical scheme of some fat-reducing aspects, as notification number is CN1235051 disclosed " Puzhi defatting health-care products ", it comprises Furctus Aurantii Immaturus extract and Folium camelliae assamicae or Pu'er tea, by improving digestive function, strengthen the body metabolism effect, the principle that increases consumption realizes preventing and treating fat purpose.Notification number is CN1404848 disclosed " fat-reducing Chinese medicine and preparation method thereof ", and it is made up of sulfur, Mirabilitum, Cortex Magnoliae Officinalis, Fructus Aurantii Immaturus, Gypsum Fibrosum.Notification number is CN1166296 disclosed " a kind of high-efficient health-care food ", and it is made up of raw materials such as Semen sojae atricolor, Semen Sesami Nigrum, Fructus Cannabis, Fructus Jujubaes, and it reduces the purpose that the intake of food is reached fat-reducing under the prerequisite that guarantees nutrition.Notification number is CN1257719 disclosed " medicinal pill for eliminating fat and beautifying face ", it is made up of Radix Arnebiae (Radix Lithospermi), Concha Haliotidis, Radix Scutellariae, Cortex Phellodendri, Flos Lonicerae, Herba Taraxaci, Radix Isatidis, Cortex Mori, Folium Eriobotryae, Rhizoma Smilacis Glabrae, Semen Arecae Prepareta, living germanite, and it reaches the effect of fat-reducing by the dissipating depression of QI of invigorating blood circulation, heat-clearing and toxic substances removing, capable the stagnating of removing food stagnancy.Notification number is CN1097628 disclosed " fast fat reducing capsule and a manufacture method thereof ", it by Herb Gynostemmae Pentaphylli, the Radix Astragali, gold carp root, Semen Pharbitidis, the Fructus Sophorae, Fructus Crataegi, Fructus Gleditsiae Abnormalis, Alumen, Semen Raphani, Semen Cassiae, fluoridize the first element, Celluloasun Microcrystallisatum is formed, it reaches the purpose of rapid fat-reducing and blood fat reducing by the form that fat is converted into energy.
Summary of the invention
One of purpose of the present invention provides the significantly vigorous and graceful weight reducing capsule of a kind of fat-reducing effect, to solve the some shortcomings part that existing diet products exist.
Two of purpose of the present invention provides the capsular preparation method of above-mentioned vigorous and graceful weight reducing.
In order to realize the foregoing invention purpose, the technical solution used in the present invention is: vigorous and graceful weight reducing capsule, its feature includes following bulk drugs active component: Herb Gynostemmae Pentaphylli dry extract 8-10 part, L-carnitine 5-6 part, Concha Haliotidis 4-5 part, Fructus Aurantii Immaturus 5-6 part, Cortex Magnoliae Officinalis 4-5 part, Fructus Cannabis 4-5 part, Flos Lonicerae 4-5 part.
The capsular preparation method of above-mentioned vigorous and graceful weight reducing may further comprise the steps:
1, pretreatment: the above-mentioned raw materials medicine is carried out pretreatment, eliminate silt and impurity, standby behind cleaning, the airing;
2, extract: Herb Gynostemmae Pentaphylli is decocted with water twice in proportion, each 2-2.5 hour, filter, filtrate is through vacuum concentration, solution concentration is carried out spray drying during to certain weight proportion, the Herb Gynostemmae Pentaphylli dry extract;
3, drying and crushing: with L-carnitine, Concha Haliotidis, Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis, Fructus Cannabis, Flos Lonicerae, soak into, sterilized 15-20 minute with 75% ethanol, place then in the drying baker, under 65 ± 2 ℃, carry out drying, moisture content in the crude drug is dropped to below 5%, and it is standby to be ground into fine powder more separately;
4, mix: Herb Gynostemmae Pentaphylli dry extract 8-10 part, L-carnitine 5-6 part, Concha Haliotidis 4-5 part, Fructus Aurantii Immaturus 5-6 part, Cortex Magnoliae Officinalis 4-5 part, Fructus Cannabis 4-5 part, Flos Lonicerae 4-5 part of taking by weighing batch volume of production are according to the above ratio put in the mixing drum and are mixed, make each component mix homogeneously, the color and luster unanimity;
5, sterilization: get the mix homogeneously powder and put in the square plate, thickness is no more than 1cm, with 100 ℃ of flowing steam sterilizations, and oven dry again after 1 hour;
6, the disinfectant mixing fine powders is packed into the good capsule of pretreatment, and load onto outer package and get final product.
Crude drug Herb Gynostemmae Pentaphylli used in the present invention is cucurbitaceous plant (GynostemmaPentaphyiium Makino), the main Saponin, flavonoid of containing; Nature and flavor hardship, cold; The function heat-clearing and toxic substances removing cures mainly lowering blood-fat and reducing weight, hyperlipidemia, obesity.Concha Haliotidis is Bao Ke animal Haliotis diversicolor (Haliotisdiversicolor Reeve), and nature and flavor become, tremble with fear; Return Liver Channel.The function suppressing the hyperactive liver and subsiding YANG, liver heat removing and eyesight improving; Cure mainly dizzy, the conjunctival congestion cataracta of headache, blurring of vision is shown blind nyctalopia.Fructus Aurantii Immaturus is the young fruit of rutaceae (Citrusaurantiuml), nature and flavor hardship, suffering, acid, temperature; Return spleen; Function dispelling the stagnated QI disappear trifoliate orange, the diffusing painful abdominal mass of reducing phlegm cure mainly that trifoliate orange stops in stagnating, the feeling of fullness distending pain.Cortex Magnoliae Officinalis is the dried bark of Magnoliacea plant (Magnoliaofficinalis Rehol ee Wlis); Nature and flavor hardship, suffering, temperature; The expectorant of function dampness, the therapeutic method to keep the adverse QI flowing downwards are removed full; Cure mainly that humidity hysteresis damaging the spleen and stomach, gastral cavity painful abdominal mass are vomited and diarrhoea, the food trifoliate orange stagnation of QI, abdominal distention constipation, phlegm dyspnea cough.Fructus Cannabis is the mature fruit of moraceae plants (Cannabis Saeiva L); Nature and flavor are sweet, flat, return spleen; The function loosening bowel to relieve constipation cures mainly blood deficiency and depleted fluid, dryness of the intestine constipation.Flos Lonicerae is for bearing the alabastrum of section plant Radix Ophiopogonis (LoniceraJaponica Thunb); Main contain luteolin, inositol, saponin, tannin etc., sweet in flavor and cold in property, the function heat-clearing and toxic substances removing, nourish blood and quench the thirst; Cure mainly epidemic febrile disease heating, toxic-heat and blood stasis, dysentery infections, toxic swelling, anal fistula.
Capsule of the present invention is through check, and its physical and chemical index sees Table 1
Table 1
| Project | Index |
| Arsenic (in As mg/kg) | ≤1.0 |
| Plumbous (in Pb mg/kg) | ≤1.5 |
| Hydrargyrum (in Hg mg/kg) | ≤0.3 |
| Total Saponin (with Lu Dingji) mg/100g | ≥500 |
| Gamma Hexaochlorocyclohexane mg/kg | ≤0.2 |
| Clofenotane mg/kg | ≤0.2 |
| Ash % | ≤6 |
| Content uniformity (%) | ≤9 |
| Water content (%) | ≤8 |
| Disintegration time (minute) | ≤30 |
Capsule microorganism of the present invention is limited the quantity of and is met the regulation of table 2
Table 2
| Project | Index |
| Total plate count | ≤1000 |
| Escherichia coli | ≤40 |
| Mycete | ≤25 |
| Yeast | ≤25 |
| Pathogenic bacterium (duodenum 12 road pathogenic bacterium and to the characteristic of disease coccus) | Must not detect |
The capsule of the present invention Simple Obesity crowd that suits, eating method and amount are secondary every day, each 4.
Clinical efficacy of the present invention is as follows:
1, fat-reducing effect.Clinical trial shows that capsule of the present invention has significant weight loss effect, generally positive effect occurs after taking for two weeks, six monthly average loss of weight 5kg, and absolute most of slimmers are satisfied to fat-reducing effect.Capsule effect of the present invention mainly is that fat content reduces.The people who takes the capsular slimmer at least 90% of the present invention demonstrates the satisfaction of medium degree (loss of weight 〉=10%) effect.
2, the contrast of loss of weight absolute number (domestic and external), domestic and external similar clinical research is compared, and the two result is closely similar.The Hunan likes that people's institute of Pharmaceutical Research result of the test shows, took in 10mg/ days and took effect in two weeks, eight weeks entered stable curative effect, two monthly average loss of weight 5kg, the treatment initial stage is loss of weight 0.5kg weekly on average, meets international health slimming requirement, and the body weight change situation to the slimmer after the off-test is carried out the follow up survey results suggest, under the prerequisite that changes hyperpyrexia high fat diet and bad life habits, but long term maintenance weight loss effect after most slimmer's drug withdrawal.
3, reduce waistline, hip circumference, reduce waist/hip circumference ratio, reducing the randomized, double-blind placebo-controlled trial that type ii diabetes patient of superabundant fats participates in the body shows: capsule 15mg/d of the present invention, took for 12 weeks, and adiposis patient reduces mainly is fat but not muscle.It 70% is fat that X ray absorption apparatus (DEXA) is measured what reduce in the treatment group experimenter soft tissue, and the total body fat tissue has reduced 1.8kg, and placebo only reduces 0.2kg (P＜0.001).Improving blood fat Combined Analysis (11 stuies) of Percentage Change in Serum Lipids result shows: matched group and treatment group are organized comparison entirely, the treatment group has the obvious effect (P＜0.05) that reduces TG, CHOL, LDL and rising HDL, and this effect strengthens with the increase of weight loss effect.
In sum, capsule of the present invention has good fat-reducing effect.
The specific embodiment
Vigorous and graceful weight reducing capsule, its feature includes following bulk drugs active component: 10 parts of Herb Gynostemmae Pentaphylli dry extracts, 6 parts of L-carnitines, 5 parts of Concha Haliotidis, 6 parts of Fructus Aurantii Immaturuss, 5 parts of Cortex Magnoliae Officinalis, 5 parts of Fructus Cannabiss, 5 parts of Flos Loniceraes.
The capsular preparation method of above-mentioned vigorous and graceful weight reducing may further comprise the steps:
1, pretreatment: the above-mentioned raw materials medicine is carried out pretreatment, eliminate silt and impurity, standby behind cleaning, the airing;
2, extract: Herb Gynostemmae Pentaphylli is decocted with water twice in proportion, each 2 hours, filter, filtrate is through vacuum concentration, solution concentration is carried out spray drying during to certain weight proportion, the Herb Gynostemmae Pentaphylli dry extract;
3, drying and crushing: with L-carnitine, Concha Haliotidis, Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis, Fructus Cannabis, Flos Lonicerae, soak into, sterilized 15-20 minute with 75% ethanol, place then in the drying baker, under 65 ± 2 ℃, carry out drying, moisture content in the crude drug is dropped to below 5%, and it is standby to be ground into fine powder more separately;
4, mix: 5 parts of 5 parts of 6 parts of 5 parts of 6 parts of 10 parts of Herb Gynostemmae Pentaphylli dry extracts, L-carnitines, Concha Haliotidis, Fructus Aurantii Immaturuss, Cortex Magnoliae Officinalis, the Fructus Cannabiss, the Flos Lonicerae that take by weighing batch volume of production are according to the above ratio put in the mixing drum for 5 parts and mix, and make each component mix homogeneously, the color and luster unanimity;
5, sterilization: get the mix homogeneously powder and put in the square plate, thickness is no more than 1cm, with 100 ℃ of flowing steam sterilizations, and oven dry again after 1 hour;
6, the disinfectant mixing fine powders is packed into the good capsule of pretreatment, and load onto outer package and get final product.
Claims (2)
1, vigorous and graceful weight reducing capsule, its feature includes following bulk drugs active component: Herb Gynostemmae Pentaphylli dry extract 8-10 part, L-carnitine 5-6 part, Concha Haliotidis 4-5 part, Fructus Aurantii Immaturus 5-6 part, Cortex Magnoliae Officinalis 4-5 part, Fructus Cannabis 4-5 part, Flos Lonicerae 4-5 part.
2, the capsular method of the described vigorous and graceful weight reducing of a kind of preparation claim 1, its feature may further comprise the steps:
[1], pretreatment: the above-mentioned raw materials medicine is carried out pretreatment, eliminate silt and impurity, clean, standby behind the airing;
[2], extract: Herb Gynostemmae Pentaphylli is decocted with water twice in proportion, each 2-2.5 hour, filter, filtrate is through vacuum concentration, solution concentration is carried out spray drying during to certain weight proportion, the Herb Gynostemmae Pentaphylli dry extract;
[3], drying and crushing: with L-carnitine, Concha Haliotidis, Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis, Fructus Cannabis, Flos Lonicerae, soak into, sterilized 15-20 minute with 75% ethanol, place then in the drying baker, under 65 ± 2 ℃, carry out drying, moisture content in the crude drug is dropped to below 5%, and it is standby to be ground into fine powder more separately;
[4], mix: Herb Gynostemmae Pentaphylli dry extract 8-10 part, L-carnitine 5-6 part, Concha Haliotidis 4-5 part, Fructus Aurantii Immaturus 5-6 part, Cortex Magnoliae Officinalis 4-5 part, Fructus Cannabis 4-5 part, Flos Lonicerae 4-5 part of taking by weighing batch volume of production are according to the above ratio put in the mixing drum and are mixed, make each component mix homogeneously, the color and luster unanimity;
[5], sterilization: get the mix homogeneously powder and put in the square plate, thickness is no more than 1cm, with 100 ℃ of flowing steam sterilizations, dries after 1 hour again;
[6], with the disinfectant mixing fine powders good capsule of pretreatment of packing into, and load onto outer package and get final product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100470713A CN100361654C (en) | 2004-12-15 | 2004-12-15 | Body-building weight-reducing capsule and its preparation process |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB2004100470713A CN100361654C (en) | 2004-12-15 | 2004-12-15 | Body-building weight-reducing capsule and its preparation process |
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| Publication Number | Publication Date |
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| CN1788761A true CN1788761A (en) | 2006-06-21 |
| CN100361654C CN100361654C (en) | 2008-01-16 |
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| CNB2004100470713A Expired - Fee Related CN100361654C (en) | 2004-12-15 | 2004-12-15 | Body-building weight-reducing capsule and its preparation process |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103006886A (en) * | 2012-12-19 | 2013-04-03 | 魏秀春 | Chinese medicinal preparation for treating constipation |
| CN103340254A (en) * | 2013-07-06 | 2013-10-09 | 朱玉芳 | Weight reducing tea |
| CN105497620A (en) * | 2015-12-24 | 2016-04-20 | 兰州古驰生物科技有限公司 | Health-care traditional Chinese medicine preparation for weight reduction and body building |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1349795A (en) * | 2000-10-19 | 2002-05-22 | 珠海威尔发展有限公司 | Compound slimming prepn and its application |
| CN1546017A (en) * | 2003-11-30 | 2004-11-17 | 杨喜鸿 | Compostion preparation of orlistat |
-
2004
- 2004-12-15 CN CNB2004100470713A patent/CN100361654C/en not_active Expired - Fee Related
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103006886A (en) * | 2012-12-19 | 2013-04-03 | 魏秀春 | Chinese medicinal preparation for treating constipation |
| CN103006886B (en) * | 2012-12-19 | 2013-12-25 | 魏秀春 | Traditional Chinese medicine preparation for treating constipation |
| CN103340254A (en) * | 2013-07-06 | 2013-10-09 | 朱玉芳 | Weight reducing tea |
| CN103340254B (en) * | 2013-07-06 | 2014-07-16 | 傅小华 | Weight reducing tea |
| CN105497620A (en) * | 2015-12-24 | 2016-04-20 | 兰州古驰生物科技有限公司 | Health-care traditional Chinese medicine preparation for weight reduction and body building |
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| Publication number | Publication date |
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| CN100361654C (en) | 2008-01-16 |
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| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Fang Yunchao Assignor: Hunan Aimin Pharmaceutical Co., Ltd. Contract record no.: 2010430000137 Denomination of invention: Body-building weight-reducing capsule and its preparation process Granted publication date: 20080116 License type: Exclusive License Open date: 20060621 Record date: 20101028 |
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| EE01 | Entry into force of recordation of patent licensing contract |
Assignee: Hunan Aimin Pharmaceutical Co., Ltd. Assignor: Fang Yunchao Contract record no.: 2010430000137 Denomination of invention: Body-building weight-reducing capsule and its preparation process Granted publication date: 20080116 License type: Exclusive License Open date: 20060621 Record date: 20101028 |
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| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20080116 Termination date: 20121215 |