CN1751751A - Immediate dispensing infusion - Google Patents

Immediate dispensing infusion Download PDF

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Publication number
CN1751751A
CN1751751A CN 200510012790 CN200510012790A CN1751751A CN 1751751 A CN1751751 A CN 1751751A CN 200510012790 CN200510012790 CN 200510012790 CN 200510012790 A CN200510012790 A CN 200510012790A CN 1751751 A CN1751751 A CN 1751751A
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China
Prior art keywords
sodium
bag
chambers
liquid pipe
dress
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CN 200510012790
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Chinese (zh)
Inventor
郝瑞霞
吴金波
刘浩
王德胜
张颜会
王志良
杨士宁
刘英华
路玉锋
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HUABEI PHARMACEUTICAL GROUP CO Ltd
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HUABEI PHARMACEUTICAL GROUP CO Ltd
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Priority to CN 200510012790 priority Critical patent/CN1751751A/en
Publication of CN1751751A publication Critical patent/CN1751751A/en
Pending legal-status Critical Current

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Abstract

An in-situ prepared perfusion is prepared instantaneously from liquid bag, liquid filling tube, clinic powder medicine and the solution for injection through making bag, installing the liquid filling tube, filling said solution, thermal sealing, sterilizing, examining by lamp light, filling powder medicine, thermal sealing and examining. Its advantages are low cost and no secondary pollution.

Description

A kind of immediate dispensing infusion
Technical field
The present invention relates to a kind of medicine, specifically a kind of immediate dispensing infusion.
Background technology
Domesticly comprise glucose or normal saline etc. with transfusion at present, it is packed to mainly contain glass bottle and common PVC, and solvent and medicine for treatment thing powder great majority all are packings separately, uses Shi Zaiyou nurse formulated together.The configuration inconvenience expends a large amount of manpowers and time when so not only causing medicine to use, and main is secondary pollution and the preparation mistake that very easily causes medicinal liquid in medicine configuration process for preparation.In addition, the transfusion of using the vial preparation is in patient's instillation process, and glass itself produces absorption to medicine easily, thereby reduces content of drug.Common PVC transfusion package bag contains plasticizer DEHP (phthalic acid two fat), easily medicinal liquid is damaged, and life-time service can cause potential hazard to people's health.Vial still is that these two kinds of packings of PVC bag all must keep internal pressure by in the air admission solution in use, allows drug solution flow down smoothly.The process that this air refluxes can cause drug contamination with having in the ward in the inclusion of air medicine of various pathogenic bacterium.Bibliographical information is arranged, and vial is as hang surpassing 48 hours, has 9% transfusion contaminated.The rubbish that vial and common PVC bag form after use all can pollute environment.
Summary of the invention
The object of the present invention is to provide a kind of transfusion that medicinal liquid is obscured can conveniently dispose and use, reduce the secondary pollution in the layoutprocedure and avoid clinical use the time, the packing charges of also having saved the medicine for treatment product simultaneously.
Process for preparation when drug use has been saved in this invention, avoided medicine extract and process for preparation in be exposed to link in the hospital environment, the medicine outside environment for use contact of getting along well fully, GMP condition when being equivalent to the medicine packing extends in the environment for use of hospital, has guaranteed that really medicine is not subjected to extraneous secondary pollution.
This invents employed soft bag because its softish material has guaranteed the pressure that medicine instils smoothly, has been avoided the air of conventional using method to reflux, and has guaranteed that use is pollution-free.
This invents employed non-PVC-soft-bag originally as the degradable product, and the rubbish after the use can not pollute environment.
Another advantage of instant-matching type venous transfusion provided by the present invention is to be fit to very much first aid and open-air rescue.
The object of the present invention is achieved like this:
1. the non-PVC bag material of the three side sealing mouth through being up to the standards carries out pressing with dress liquid pipe in Bag Making Machine, or cut off in the hot pressing in place, make non-PVC bag become two chambers (accompanying drawing 1) or three chambers (accompanying drawing 2), wherein adorn the liquid pipe and link to each other with the chamber of dress injection liquid, the edge of other chambers carries out hot pressing.
2. pour into the injection solution (5% glucose injection or 10% glucose injection or 0.9% sodium chloride injection) for preparing, gland by dress liquid pipe.
The semi-finished product that 3. injection liquid is housed are placed in the rustless steel unwheeling, with the Water-heating shower sterilization, and cooling naturally then, drying, lamp inspection.
4. qualified semi-finished product of lamp inspection at first cut away the edge of flour bag, pour into medicated powder after, use hot-press sealed.
When non-PVC bag material is made two chambers, be applicable to that medicine powder and non-PVC packaging material have the medicine of excellent compatibility.Only need crowdedly gently rub the separation position during use two zones that are separated are connected, then, mix that medicine powder is dissolved fully, can use after remix is even.
When non-PVC bag material is made three chambers, wherein connect the chamber fill injection liquid of pouring pipe, all the other two chambers one are to be used for fill medicine powder, and another is to be used for the fill cosolvent.This packing is applicable to the fill insoluble drug.Squeeze the separation position of rubbing between medicine powder and the cosolvent during use earlier gently, these two zones that are separated are connected, then, after mixing is dissolved medicine powder fully, squeeze the separation position of rubbing between medicinal liquid and the injection solution more gently, will can use behind the medicinal liquid mix homogeneously at last.
When the bad medicine of fill medicine powder and the long-term contact compatibility of non-PVC packaging material, not hot pressing cuts off on the non-PVC bag that makes, and only has a chamber, is used for the fill injection liquid.Medicine powder is packed in the aseptic compound lid tube cell of having of compression moulding, and grafting easy-to-fold cap (accompanying drawing 3).In aseptic area, the dress liquid pipe on the liquid semi-finished product is cut off,, sealed molding then the downward dress liquid pipe that inserts after cutting of the easy-to-fold cap of medicine tube cell.Be equipped with between region of fluid and the medicated powder pipe and separate, form two zones of a packaging bag by easy-to-fold cap.The easy-to-fold cap that only need fracture gently during use can place injection solution with medicine powder, then, mixes that medicine powder is dissolved fully, and remix can use after evenly.
Three kinds of transfusions shown in accompanying drawing 1, accompanying drawing 2 and accompanying drawing 3 can also be again when press-fiting the liquid pipe and one of the row pressure pipe (accompanying drawing 4) that makes up a prescription, can add other medicines from the pipe that makes up a prescription where necessary.
Employed non-PVC bag material (U.S. Xi Yueer company, model is M312) is the thin film of being made by employing co-extrusion technologies such as polyethylene, ethylene methacrylic acid lipopolymer, multi-ester copolymer and electronic crosslinking technology by 5 layers of structure (about 190 microns of gross thickness) among the present invention.
Medicine powder can be to be used for the medicine of intravenous drip clinically.
When medicine powder is penicillins, can be Amoxicillin Sodium/sulbactam sodium, also can be that piperacillin sodium/tazobactam sodium or avocin/sulbactam sodium or mezlocillin sodium or mezlocillin sodium/sulbactam sodium or ticarcillin sodium/clavulanate potassium or Amoxicillin Sodium/clavulanate potassium or Amoxicillin Sodium/flucloxacillin sodium or ampicillin/cloxacillin sodium or ampicillin/sulbactam sodium or penicillin sodium or amoxicillin are received or azlocillin sodium or avocin etc.
When medicine powder was penicillins, it can be packed into had in the medicated powder pipe that emits easy to break (accompanying drawing 3).
When medicine powder is the cephalo-type medicine, can be Cefuroxime Sodium or cefpirome, also can be ceftazidime or Cefminox sodium or cefoperazone sodium/sulbactam sodium or cefonicid sodium or Cefodizime Sodium or cefoxitin sodium or cefepime or cefotiam or cefmetazole or ceftizoxime or cefotaxime/sulbactam sodium or cefamandole or ceftriaxone sodium or cefoperazone sodium, cefradine or cefazolin sodium etc.
During blue or green non-the similar drug of medicine powder right and wrong; Can be clindamycin phosphate, also can be pefloxacin mesilate or Levofloxacin M. S. A or Pazufloxacin Mesilate or GCV or Fluconazole or gatifloxacin or fleraxacin or UTI or Netilmicin or Lomefloxacin or Ornidazole or Alprostadil or Isosorbide Mononitrate or buflomedil or sodium ozagrel or metoprolol or THP or Coenzyme Complex or tranexamic acid or citicoline or oxaliplatin or glutathione or Granisetron or gemcitabine or Pamidronic Acid disodium or Puerarin or Pantoprazole Sodium or famotidine or Potassium Magnesium Aspartate etc. Need when adorning these medicines non-PVC bag is made two chambers (accompanying drawing 1).
Blue or green non-the quasi drugs of medicine powder right and wrong can be azithromycin, also can be norvancomycin hydrochloride or tiopronin.Need when adorning these medicines non-PVC bag is made three chambers (accompanying drawing 2).
The loading amount of injection solution can be 50 milliliters, also can be 100 milliliters or 250 milliliters etc.
Description of drawings:
Accompanying drawing 1 has the immediate dispensing infusion of two chambers
Accompanying drawing 2 has the immediate dispensing infusion of three chambers
Accompanying drawing 3 has the immediate dispensing infusion of medicated powder pipe
Accompanying drawing 4 has the immediate dispensing infusion of the pipe that makes up a prescription
Below by embodiment the present invention is further described:
Embodiment 1
The non-PVC bag material (U.S. Xi Yueer company of learning from else's experience and being up to the standards, model is M312) last machine (the bag zone is the local laminar flow under ten thousand grades), Bag Making Machine is earlier with three pressings of film material, in position press partition (accompanying drawing 1), the bag material is divided into two chambers, and another open section carries out pressing with dress liquid pipe.The semi-finished product bag of liquid pipe is adorned in pressing well, and is slowly upright under the effect of conveyer belt and mechanical external force, and one section of dress liquid pipe up, enter and irritate the liquid racking machine, 0.9% pre-configured sodium chloride injection through the medicinal liquid racking machine, is injected interior 100 milliliters of bag, gland from dress liquid pipe.Irritate the semi-finished product that liquid finishes, with 105 ℃ of hot water pyretic stranguria sterilization 30min, lower the temperature naturally then, drying, lamp inspection.The semi-finished product that lamp inspection is qualified, enter powder-filling machine fro by conveyer belt, at first cut away the edge of another chamber bag, under the effect of mechanical external force, make sack upright, clindamycin phosphate medicated powder 0.6 gram that is up to the standards is passed through screw type sub packaging machine, pack in the bag, hot-press sealed is sealed up airtight outer bag again, packing is examined warehousing after passing entirely.
Embodiment 2
The non-PVC bag material (U.S. Xi Yueer company of learning from else's experience and being up to the standards, model is M312) last machine (the bag zone is the local laminar flow under ten thousand grades), Bag Making Machine is earlier with three pressings of film material, in position press partition (accompanying drawing 1), the bag material is divided into two chambers, and another open section carries out pressing with dress liquid pipe.The semi-finished product bag of liquid pipe is adorned in pressing well, and is slowly upright under the effect of conveyer belt and mechanical external force, and one section of dress liquid pipe up, enter and irritate the liquid racking machine, 5% pre-configured glucose injection through the medicinal liquid racking machine, is injected interior 100 milliliters of bag, gland from dress liquid pipe.Irritate the semi-finished product that liquid finishes, with 105 ℃ of hot water pyretic stranguria sterilization 30min, lower the temperature naturally then, drying, lamp inspection.The semi-finished product that lamp inspection is qualified, enter powder-filling machine fro by conveyer belt, at first cut away the edge of another chamber bag, under the effect of mechanical external force, make sack upright, puerarin medicated powder 0.2 gram that is up to the standards is passed through screw type sub packaging machine, pack in the bag, hot-press sealed is sealed up airtight outer bag again, packing is examined warehousing after passing entirely.
Embodiment 3
The non-PVC bag material (U.S. Xi Yueer company of learning from else's experience and being up to the standards, model is M312) last machine (the bag zone is the local laminar flow under ten thousand grades), Bag Making Machine is earlier with three pressings of film material, in position press partition (accompanying drawing 1), the bag material is divided into two chambers, and another open section carries out pressing with dress liquid pipe.The semi-finished product bag of liquid pipe is adorned in pressing well, and is slowly upright under the effect of conveyer belt and mechanical external force, and one section of dress liquid pipe up, enter and irritate the liquid racking machine, 0.9% pre-configured sodium chloride injection through the medicinal liquid racking machine, is injected interior 100 milliliters of bag, gland from dress liquid pipe.Irritate the semi-finished product that liquid finishes, with 105 ℃ of hot water pyretic stranguria sterilization 30min, lower the temperature naturally then, drying, lamp inspection.The semi-finished product that lamp inspection is qualified, enter powder-filling machine fro by conveyer belt, at first cut away the edge of another chamber bag, under the effect of mechanical external force, make sack upright, clindamycin phosphate medicated powder 0.3 gram that is up to the standards is passed through screw type sub packaging machine, pack in the bag, hot-press sealed is sealed up airtight outer bag again, packing is examined warehousing after passing entirely.
Embodiment 4
The non-PVC bag material (U.S. Xi Yueer company of learning from else's experience and being up to the standards, model is M312) go up machine (the bag zone is the local laminar flow under ten thousand grades), Bag Making Machine in position presses partition (accompanying drawing 2) earlier with three pressings of film material, the bag material is divided into three chambers, and another side carries out pressing with dress liquid pipe.The semi-finished product bag of liquid pipe is adorned in pressing well, and is slowly upright under the effect of conveyer belt and mechanical external force, and one section of dress liquid pipe up, enter and irritate the liquid racking machine, 0.9% pre-configured sodium chloride injection through the medicinal liquid racking machine, is injected interior 100 milliliters of bag, gland from dress liquid pipe.Irritate the semi-finished product that liquid finishes, with 105 ℃ of hot water pyretic stranguria sterilization 30min, lower the temperature naturally then, drying, lamp inspection.The semi-finished product that lamp inspection is qualified enter powder-filling machine fro by conveyer belt, at first cut away the edge of upper left corner chamber bag, under the effect of mechanical external force, make sack upright, and azithromycin medicated powder 0.2 gram that is up to the standards is passed through screw type sub packaging machine, in the bag of packing into, and hot-press sealed.Then, cut away the edge of upper right corner chamber bag again, under the effect of mechanical external force, make sack upright, in 3 milliliters of bags of packing into of cosolvent water for injection, hot-press sealed.At last, seal up airtight outer bag, packing is examined warehousing after passing entirely.
Embodiment 5
The non-PVC bag material (U.S. Xi Yueer company, model is M312) that is up to the standards of learning from else's experience is gone up machine (the bag zone is the local laminar flow under ten thousand grades), and Bag Making Machine presses the dress liquid pipe and the pipe (accompanying drawing 4) that makes up a prescription earlier with three pressings of film material on another side.The semi-finished product bag of liquid pipe is adorned in pressing well, and is slowly upright under the effect of conveyer belt and mechanical external force, and one section of dress liquid pipe up, enter and irritate the liquid racking machine, 0.9% pre-configured sodium chloride injection through the medicinal liquid racking machine, is injected interior 100 milliliters of bag, heat-sealing from dress liquid pipe.Irritate the semi-finished product that liquid finishes, with 105 ℃ of hot water pyretic stranguria sterilization 30min, lower the temperature naturally then, drying, lamp inspection.Amoxicillin Sodium/sulbactam sodium (2: 1) medicated powder of being up to the standards 1.5 grams by screw type sub packaging machine, in the tube cell of packing into, are jumped a queue, gland then.Cut away the heat seal lands of the dress liquid pipe that injection liquid is housed, the tube cell easy-to-fold cap that medicated powder is housed is inserted dress liquid pipe after the shearing downwards, seal molding then.Lamp inspection, packing, examine warehousing after passing entirely.
Embodiment 6
The non-PVC bag material (U.S. Xi Yueer company, model is M312) that is up to the standards of learning from else's experience is gone up machine (the bag zone is the local laminar flow under ten thousand grades), and Bag Making Machine presses dress liquid pipe (accompanying drawing 3) earlier with three pressings of film material on another side.The semi-finished product bag of liquid pipe is adorned in pressing well, and is slowly upright under the effect of conveyer belt and mechanical external force, and one section of dress liquid pipe up, enter and irritate the liquid racking machine, 5% pre-configured glucose injection through the medicinal liquid racking machine, is injected interior 250 milliliters of bag, heat-sealing from dress liquid pipe.Irritate the semi-finished product that liquid finishes, with 105 ℃ of hot water pyretic stranguria sterilization 30min, lower the temperature naturally then, drying, lamp inspection.Piperacillin sodium/tazobactam sodium (8: 1) medicated powder 4.5 grams that are up to the standards are passed through screw type sub packaging machine, and packing into, tube cell interior (accompanying drawing 3) is jumped a queue then, gland.Cut away the heat seal lands of the dress liquid pipe that injection liquid is housed, the tube cell easy-to-fold cap that medicated powder is housed is inserted dress liquid pipe after the shearing downwards, seal molding then.Lamp inspection, packing, examine warehousing after passing entirely.
Embodiment 7
The non-PVC bag material (U.S. Xi Yueer company, model is M312) that is up to the standards of learning from else's experience is gone up machine (the bag zone is the local laminar flow under ten thousand grades), and Bag Making Machine presses dress liquid pipe (accompanying drawing 3) earlier with three pressings of film material on another side.The semi-finished product bag of liquid pipe is adorned in pressing well, and is slowly upright under the effect of conveyer belt and mechanical external force, and one section of dress liquid pipe up, enter and irritate the liquid racking machine, 0.9% pre-configured sodium chloride injection through the medicinal liquid racking machine, is injected interior 50 milliliters of bag, heat-sealing from dress liquid pipe.Irritate the semi-finished product that liquid finishes, with 105 ℃ of hot water pyretic stranguria sterilization 30min, lower the temperature naturally then, drying, lamp inspection.Mezlocillin for inj medicated powder 1.0 grams that are up to the standards are passed through screw type sub packaging machine, and packing into, tube cell interior (accompanying drawing 3) is jumped a queue then, gland.Cut away the heat seal lands of the dress liquid pipe that injection liquid is housed, the tube cell easy-to-fold cap that medicated powder is housed is inserted dress liquid pipe after the shearing downwards, seal molding then.Lamp inspection, packing, examine warehousing after passing entirely.
Embodiment 8
The non-PVC bag material (U.S. Xi Yueer company, model is M312) that is up to the standards of learning from else's experience is gone up machine (the bag zone is the local laminar flow under ten thousand grades), and Bag Making Machine presses dress liquid pipe (accompanying drawing 3) earlier with three pressings of film material on another side.The semi-finished product bag of liquid pipe is adorned in pressing well, and is slowly upright under the effect of conveyer belt and mechanical external force, and one section of dress liquid pipe up, enter and irritate the liquid racking machine, 5% pre-configured glucose injection through the medicinal liquid racking machine, is injected interior 100 milliliters of bag, heat-sealing from dress liquid pipe.Irritate the semi-finished product that liquid finishes, with 105 ℃ of hot water pyretic stranguria sterilization 30min, lower the temperature naturally then, drying, lamp inspection.Azlocillin sodium for injection medicated powder 2.0 grams that are up to the standards are passed through screw type sub packaging machine, and packing into, tube cell interior (accompanying drawing 3) is jumped a queue then, gland.Cut away the heat seal lands of the dress liquid pipe that injection liquid is housed, the tube cell easy-to-fold cap that medicated powder is housed is inserted dress liquid pipe after the shearing downwards, seal molding then.Lamp inspection, packing, examine warehousing after passing entirely.
Embodiment 9
The non-PVC bag material (U.S. Xi Yueer company of learning from else's experience and being up to the standards, model is M312) last machine (the bag zone is the local laminar flow under ten thousand grades), Bag Making Machine is earlier with three pressings of film material, in position press partition (accompanying drawing 1), the bag material is divided into two chambers, and another open section carries out pressing with dress liquid pipe.The semi-finished product bag of liquid pipe is adorned in pressing well, and is slowly upright under the effect of conveyer belt and mechanical external force, and one section of dress liquid pipe up, enter and irritate the liquid racking machine, 0.9% pre-configured sodium chloride injection through the medicinal liquid racking machine, is injected interior 50 milliliters of bag, gland from dress liquid pipe.Irritate the semi-finished product that liquid finishes, with 105 ℃ of hot water pyretic stranguria sterilization 30min, lower the temperature naturally then, drying, lamp inspection.The semi-finished product that lamp inspection is qualified, enter powder-filling machine fro by conveyer belt, at first cut away the edge of another chamber bag, under the effect of mechanical external force, make sack upright, Cefuroxime Sodium medicated powder 1.5 grams that are up to the standards are passed through screw type sub packaging machine, pack in the bag, hot-press sealed is sealed up airtight outer bag again, packing is examined warehousing after passing entirely.
Embodiment 10
The non-PVC bag material (U.S. Xi Yueer company of learning from else's experience and being up to the standards, model is M312) last machine (the bag zone is the local laminar flow under ten thousand grades), Bag Making Machine is earlier with three pressings of film material, in position press partition (accompanying drawing 1), the bag material is divided into two chambers, and another open section carries out pressing with dress liquid pipe.The semi-finished product bag of liquid pipe is adorned in pressing well, and is slowly upright under the effect of conveyer belt and mechanical external force, and one section of dress liquid pipe up, enter and irritate the liquid racking machine, 5% pre-configured glucose injection through the medicinal liquid racking machine, is injected interior 100 milliliters of bag, gland from dress liquid pipe.Irritate the semi-finished product that liquid finishes, with 105 ℃ of hot water pyretic stranguria sterilization 30min, lower the temperature naturally then, drying, lamp inspection.The semi-finished product that lamp inspection is qualified, enter powder-filling machine fro by conveyer belt, at first cut away the edge of another chamber bag, under the effect of mechanical external force, make sack upright, cefpirome medicated powder 1.0 grams that are up to the standards are passed through screw type sub packaging machine, pack in the bag, hot-press sealed is sealed up airtight outer bag again, packing is examined warehousing after passing entirely.
Embodiment 11
The non-PVC bag material (U.S. Xi Yueer company of learning from else's experience and being up to the standards, model is M312) last machine (the bag zone is the local laminar flow under ten thousand grades), Bag Making Machine is earlier with three pressings of film material, in position press partition (accompanying drawing 1), the bag material is divided into two chambers, and another open section carries out pressing with dress liquid pipe.The semi-finished product bag of liquid pipe is adorned in pressing well, and is slowly upright under the effect of conveyer belt and mechanical external force, and one section of dress liquid pipe up, enter and irritate the liquid racking machine, 0.9% pre-configured sodium chloride injection through the medicinal liquid racking machine, is injected interior 200 milliliters of bag, gland from dress liquid pipe.Irritate the semi-finished product that liquid finishes, with 105 ℃ of hot water pyretic stranguria sterilization 30min, lower the temperature naturally then, drying, lamp inspection.The semi-finished product that lamp inspection is qualified, enter powder-filling machine fro by conveyer belt, at first cut away the edge of another chamber bag, under the effect of mechanical external force, make sack upright, send ketone sodium/sulbactam sodium medicated powder 2.0 grams to pass through screw type sub packaging machine the cephalo that is up to the standards, pack in the bag, hot-press sealed is sealed up airtight outer bag again, packing is examined warehousing after passing entirely.
Embodiment 12
The non-PVC bag material (U.S. Xi Yueer company of learning from else's experience and being up to the standards, model is M312) last machine (the bag zone is the local laminar flow under ten thousand grades), Bag Making Machine is earlier with three pressings of film material, in position press partition (accompanying drawing 1), the bag material is divided into two chambers, and another open section carries out pressing with dress liquid pipe.The semi-finished product bag of liquid pipe is adorned in pressing well, and is slowly upright under the effect of conveyer belt and mechanical external force, and one section of dress liquid pipe up, enter and irritate the liquid racking machine, 10% pre-configured glucose injection through the medicinal liquid racking machine, is injected interior 100 milliliters of bag, gland from dress liquid pipe.Irritate the semi-finished product that liquid finishes, with 105 ℃ of hot water pyretic stranguria sterilization 30min, lower the temperature naturally then, drying, lamp inspection.The semi-finished product that lamp inspection is qualified, enter powder-filling machine fro by conveyer belt, at first cut away the edge of another chamber bag, under the effect of mechanical external force, make sack upright, Cefminox sodium medicated powder 1.0 grams that are up to the standards are passed through screw type sub packaging machine, pack in the bag, hot-press sealed is sealed up airtight outer bag again, packing is examined warehousing after passing entirely.

Claims (9)

1, a kind of immediate dispensing infusion, it comprises dress liquid bag, dress liquid pipe, available medicated powder and injection solution clinically, it is characterized in that and dress liquid bag can be divided into a plurality of chambers, is respectively applied for available clinically medicated powder of dress and injection solution.
2, immediate dispensing infusion according to claim 1 is characterized in that adopting hot pressing mode will adorn the liquid bag and is divided into two chambers (accompanying drawing 1) or three chambers (accompanying drawing 2).
3, immediate dispensing infusion according to claim 1 is characterized in that and can make dress liquid bag become two chambers (accompanying drawing 3) at the dress liquid pipe interpolation tube cell that is used as medicine.
4, immediate dispensing infusion according to claim 2, to adorn the hot pressing in position of liquid bag and be divided into two chambers, it is characterized in that the medicated powder of being adorned is the cephalo-type medicine, can be Cefuroxime Sodium or cefpirome or ceftazidime or Cefminox sodium or cefoperazone sodium/sulbactam sodium or cefonicid sodium or Cefodizime Sodium or cefoxitin sodium or cefepime or cefotiam or cefmetazole or ceftizoxime or cefotaxime/sulbactam sodium or cefamandole or ceftriaxone sodium etc.
5, immediate dispensing infusion according to claim 2, to adorn the hot pressing in position of liquid bag and be divided into two chambers, it is characterized in that the medicated powder of being adorned is non-quasi drugs of non-green grass or young crops, can be pefloxacin mesilate or Levofloxacin M. S. A or Pazufloxacin Mesilate or ganciclovir or fluconazol or Gatifloxacin or fleroxacin or ulinastatin or netilmicin or lomefloxacin or ornidazole or Alprostadil or isosorbide mononitrate or buflomedil or sodium ozagrel or metoprolol or pirarubicin or Coenzyme Complex or tranexamic acid or citicoline or oxaliplatin or glutathion or granisetron or gemcitabine or Pamidronic Acid disodium or puerarin or Pantoprazole Sodium or famotidine or motassium magnessium aspartate etc.
6, immediate dispensing infusion according to claim 2, to adorn the hot pressing in position of liquid bag and be divided into three chambers, it is characterized in that institute's powder charge powder is the slightly solubility medicine, can be azithromycin or norvancomycin hydrochloride or tiopronin, and the 3rd chamber is used to adorn cosolvent.
7, immediate dispensing infusion according to claim 3, it is characterized in that the medicated powder of being adorned is the penicillins medicine, can be Amoxicillin Sodium/sulbactam sodium or piperacillin sodium/tazobactam sodium or avocin/sulbactam sodium or mezlocillin sodium or mezlocillin sodium/sulbactam sodium or ticarcillin sodium/clavulanate potassium or Amoxicillin Sodium/clavulanate potassium or Amoxicillin Sodium/flucloxacillin sodium or ampicillin/cloxacillin sodium or ampicillin/sulbactam sodium or penicillin sodium or the amoxicillin is received or azlocillin sodium or avocin etc.
8,, it is characterized in that injection solution can be 5% glucose injection or 10% glucose injection or 0.9% sodium chloride injection according to the described immediate dispensing infusion of claim 1.
9, immediate dispensing infusion according to claim 1 is characterized in that having the pipe that makes up a prescription with dress liquid tube side-by-side, is used to add other medicines in case of necessity.
CN 200510012790 2005-09-07 2005-09-07 Immediate dispensing infusion Pending CN1751751A (en)

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Cited By (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102100666A (en) * 2011-01-17 2011-06-22 南京新港医药有限公司 New moxifloxacin hydrochloride injection
CN102218029A (en) * 2010-07-29 2011-10-19 吴赣英 Formula, preparation method and use of pefloxacin mesylate liposome combined medicament
CN102406544A (en) * 2011-11-29 2012-04-11 湖南科伦制药有限公司 Azithromycin lactobionateinjection solution packaged by double-cavity bag and preparation method
CN102429860A (en) * 2011-11-29 2012-05-02 湖南科伦制药有限公司 Double-cavity bag packed cefpirome sulfate injection and preparation method thereof
CN102431664A (en) * 2011-08-30 2012-05-02 北京锐业制药有限公司 Production method of cefpirome sulfate/ sodium chloride injection non-PVC (polyvinyl chloride) instant matched injection
CN102429861A (en) * 2011-11-29 2012-05-02 湖南科伦制药有限公司 Cefradine injection packed by double-cavity bag and preparation method thereof
CN102429863A (en) * 2011-11-29 2012-05-02 湖南科伦制药有限公司 Azithromycin injection packed by double-cavity bag and preparation method thereof
CN102600187A (en) * 2011-01-19 2012-07-25 四川科伦药物研究有限公司 Amino acid and glucose injection packaged by dual-chambered bag, and preparation method of the injection
CN104887621A (en) * 2015-05-28 2015-09-09 浙江长典医药有限公司 Children pharmaceutical composition containing ceftriaxone sodium and low-sodium carrier
CN104906034A (en) * 2015-05-28 2015-09-16 浙江长典医药有限公司 Cefuroxime sodium and low-sodium carrier drug composition for children
CN104906033A (en) * 2015-05-28 2015-09-16 浙江长典医药有限公司 Children type cefmetazole sodium and low-sodium carrier medicine composition
CN104922678A (en) * 2015-05-28 2015-09-23 浙江长典医药有限公司 Child-type medicinal composition with ampicillin sulbactam sodium and low-sodium carrier
CN104940130A (en) * 2015-05-28 2015-09-30 浙江长典医药有限公司 Children type azlocillin sodium and low-sodium carrier pharmaceutical composition
CN104958253A (en) * 2015-05-28 2015-10-07 浙江长典医药有限公司 Child type amoxicillin sulbactam sodium and low-sodium carrier medicine composition
CN105267141A (en) * 2015-05-28 2016-01-27 浙江长典医药有限公司 Ceftezole sodium compound entity for children and preparation therefor
CN105395474A (en) * 2015-05-28 2016-03-16 浙江长典医药有限公司 Children type ceftezole sodium and low-sodium carrier pharmaceutical composition
CN108690050A (en) * 2018-06-14 2018-10-23 华北制药河北华民药业有限责任公司 A kind of purification process of sulbactam

Cited By (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102218029A (en) * 2010-07-29 2011-10-19 吴赣英 Formula, preparation method and use of pefloxacin mesylate liposome combined medicament
CN102100666A (en) * 2011-01-17 2011-06-22 南京新港医药有限公司 New moxifloxacin hydrochloride injection
CN102600187B (en) * 2011-01-19 2014-07-02 四川科伦药物研究有限公司 Amino acid and glucose injection packaged by dual-chambered bag, and preparation method of the injection
CN102600187A (en) * 2011-01-19 2012-07-25 四川科伦药物研究有限公司 Amino acid and glucose injection packaged by dual-chambered bag, and preparation method of the injection
CN102431664A (en) * 2011-08-30 2012-05-02 北京锐业制药有限公司 Production method of cefpirome sulfate/ sodium chloride injection non-PVC (polyvinyl chloride) instant matched injection
CN102429861A (en) * 2011-11-29 2012-05-02 湖南科伦制药有限公司 Cefradine injection packed by double-cavity bag and preparation method thereof
CN102429863A (en) * 2011-11-29 2012-05-02 湖南科伦制药有限公司 Azithromycin injection packed by double-cavity bag and preparation method thereof
CN102429860A (en) * 2011-11-29 2012-05-02 湖南科伦制药有限公司 Double-cavity bag packed cefpirome sulfate injection and preparation method thereof
CN102406544A (en) * 2011-11-29 2012-04-11 湖南科伦制药有限公司 Azithromycin lactobionateinjection solution packaged by double-cavity bag and preparation method
CN104906033A (en) * 2015-05-28 2015-09-16 浙江长典医药有限公司 Children type cefmetazole sodium and low-sodium carrier medicine composition
CN104906034A (en) * 2015-05-28 2015-09-16 浙江长典医药有限公司 Cefuroxime sodium and low-sodium carrier drug composition for children
CN104887621A (en) * 2015-05-28 2015-09-09 浙江长典医药有限公司 Children pharmaceutical composition containing ceftriaxone sodium and low-sodium carrier
CN104922678A (en) * 2015-05-28 2015-09-23 浙江长典医药有限公司 Child-type medicinal composition with ampicillin sulbactam sodium and low-sodium carrier
CN104940130A (en) * 2015-05-28 2015-09-30 浙江长典医药有限公司 Children type azlocillin sodium and low-sodium carrier pharmaceutical composition
CN104958253A (en) * 2015-05-28 2015-10-07 浙江长典医药有限公司 Child type amoxicillin sulbactam sodium and low-sodium carrier medicine composition
CN105267141A (en) * 2015-05-28 2016-01-27 浙江长典医药有限公司 Ceftezole sodium compound entity for children and preparation therefor
CN105395474A (en) * 2015-05-28 2016-03-16 浙江长典医药有限公司 Children type ceftezole sodium and low-sodium carrier pharmaceutical composition
CN108690050A (en) * 2018-06-14 2018-10-23 华北制药河北华民药业有限责任公司 A kind of purification process of sulbactam
CN108690050B (en) * 2018-06-14 2019-11-08 华北制药河北华民药业有限责任公司 A kind of purification process of sulbactam

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