CN1745842A

CN1745842A - Chinese medicine for treating acute and chronic hepatitis and hepatocirrhosis, its preparation thereof

Info

Publication number: CN1745842A
Application number: CNA200510094248XA
Authority: CN
Inventors: 金义生; 金琳
Original assignee: Individual
Current assignee: Individual
Priority date: 2005-09-03
Filing date: 2005-09-03
Publication date: 2006-03-15
Anticipated expiration: 2025-09-03
Also published as: CN100396323C

Abstract

An orally taken Chinese medicine for treating acute or chronic hepatitis and hepatocirrhosis is prepared from 7 Chinese-medicinal materials including subprostrate sophora root, astragalus root, human placenta, ground bettle, etc.

Description

Chinese medicine of treatment acute, chronic hepatitis, liver cirrhosis and preparation method thereof

Technical field

The invention belongs to technical field of Chinese medicines.Particularly a kind of Chinese medicine for the treatment of hepatopathys such as acute hepatitis, chronic hepatitis, liver cirrhosis and preparation method thereof.

Background technology

Chronic hepatitis is a kind of common frequently-occurring disease, wherein the hepatitis virus carrier in state-owned people more than 200,000,000, most of hepatic lesions are chronic progressive external development, its main pathological change is that inflammation and hepatic fibrosis exist simultaneously, and latter's direct result is a liver cirrhosis, even develops into hepatocarcinoma.Domestic at present even external all the shortage, effectively reversed the clinical treatment medicine that hepatic fibrosis becomes.Therefore, the ideal treatment medicine that the research and development anti-hepatic fibrosis becomes is the important topic of current medical research.

Summary of the invention

The objective of the invention is to overcome the shortcoming that prior art exists, a kind of hepatopathy symptom and sign that is used to improve is provided, promote liver function recovery, microcirculation improvement improves body's immunological function, the Chinese medicine of prevention, the development of blocking-up liver fiber.Another object of the present invention provides the preparation method of this medicine.

The objective of the invention is to be achieved through the following technical solutions:

Medicament selection Radix Sophorae Tonkinensis of the present invention, the Radix Astragali, Placenta Hominis, Carapax Trionycis, Eupolyphaga Seu Steleophaga, Radix Curcumae and rhizoma sparganic carry out prescription.These medicines are combined to make the merit of the existing blood circulation promoting and blood stasis dispelling of this Chinese medicine, and the merit of nourishing the blood and yin is arranged again, makes it invigorate blood circulation and just do not hinder.Wherein the monarch drug Radix Sophorae Tonkinensis has antiviral, falls the enzyme function, the Radix Astragali can improve body immunity; Carapax Trionycis, Eupolyphaga Seu Steleophaga, rhizoma sparganic, Radix Curcumae have the merit of stronger blood circulation promoting and blood stasis dispelling, can reduce globulin, rise albumin, and the Placenta Hominis vigorate qi and replenish the blood is mended deficiency of both YIN and YANG, and the function of this reduction of returning is arranged.

The consumption of each crude drug of medicine of the present invention is that the inventor gropes to sum up to draw in a large number, all has curative effect preferably in the scope of following weight parts:

Radix Sophorae Tonkinensis 25-30 part

Radix Astragali 20-25 part

Carapax Trionycis 5-15 part

Eupolyphaga Seu Steleophaga 5-10 part

Placenta Hominis 4-10 part

Radix Curcumae 8-15 part

Rhizoma sparganic 7-12 part.

Be preferably:

27 parts of Radix Sophorae Tonkinensiss

23 parts of the Radixs Astragali

8 parts of Carapax Trionycis

5 parts of Eupolyphaga Seu Steleophagas

4 parts of Placenta Hominiss

8 parts of Radix Curcumaes

7 parts of rhizoma sparganic.

Chinese medicine of the present invention can adopt the conventional method of Chinese medicine preparation to be prepared into any conventional oral preparations.For example can be with these crude drug decocting together except that Placenta Hominis, the condensed water decocting liquid is mixed and made into the Placenta Hominis powder more then.But these are not used in restriction protection scope of the present invention.

Preferably, preparation method of the present invention is as follows:

(1) takes by weighing each crude drug, standby in proportion;

(2) with described weight proportion Radix Sophorae Tonkinensis 2/3, the Radix Astragali 5/6 with rhizoma sparganic section after add in the water of 5 times of amounts and soaked about 3 hours;

The medical material that (3) will soak decocted 3 hours; The decocting that medicinal residues is added again 2 times of amounts boiled 2 hours, slagging-off; Merge decocting liquid twice;

(4) medicinal liquid after will merging precipitates about 12 hours, gets its supernatant and gets medicinal liquid;

(5) concentrate: will go up clear liquid medicine and be concentrated into the concentrated solution that relative density is 1.2-1.4;

(6) with described weight proportion Radix Sophorae Tonkinensis 1/3, the Radix Astragali 1/6 and Placenta Hominis, Eupolyphaga Seu Steleophaga, Carapax Trionycis, Radix Curcumae be ground into powder respectively after mix homogeneously get mixed powder;

(7) mixed powder of step (6) is added in step (5) the gained concentrated solution make even soft material, granulate with 22 mesh sieves;

(8) dry, 20 mesh sieve granulate;

(9) incapsulate, get finished medicines.

Medicine of the present invention has the function of blood circulation promoting and blood stasis dispelling, nourishing the blood and yin, and rapid-action, taking convenience, mouthfeel are good.Treatment acute, chronic hepatitis, liver cirrhosis all had better curative effect.

The specific embodiment

Further set forth the present invention and effect with clinical practice by the following examples.

Embodiment 1

Prescription: Radix Sophorae Tonkinensis 270g Radix Astragali 230g Placenta Hominis 40g

Carapax Trionycis 80g Eupolyphaga Seu Steleophaga 50g Radix Curcumae 80g rhizoma sparganic 70g

Method for making:

1, get in proportion Radix Sophorae Tonkinensis, the Radix Astragali, rhizoma sparganic, rinse well, the section; Get the above-mentioned three kinds of medical materials after cleaning, add water 4100g and soaked 3 hours;

2, above-mentioned medical material decocts with water twice, 3 hours for the first time, adds water 1640g for the second time and fries in shallow oil 2 hours; Remove medicinal residues twice medicinal liquid merged, precipitate 12 hours, remove its supernatant liquid filtering, get medicinal liquid; Filtrate concentrates 18 hours, is concentrated into relative density and reaches 1.2-1.4;

3, take by weighing a certain proportion of Placenta Hominis powder, Eupolyph aga sinesis Walker, turmeric powder, turtle ' s carapace powder, Radix Sophorae Tonkinensis powder, astragalus membranaceus powder, mix homogeneously.

4, with concentrated solution mixed material is made soft material, 22 mesh sieves are granulated, 60 ℃ of dryings, and 20 mesh sieve granulate, dry powder mixing incapsulate makes 1000 of capsules (every 0.45g).

Embodiment 2

Prescription: Radix Sophorae Tonkinensis 250g Radix Astragali 240g Placenta Hominis 50g

Carapax Trionycis 70g Eupolyphaga Seu Steleophaga 60g Radix Curcumae 90g rhizoma sparganic 70g

Method for making:

1, get in proportion Radix Sophorae Tonkinensis, the Radix Astragali, rhizoma sparganic, rinse well, the section; Get the above-mentioned three kinds of medical materials after cleaning, soaked 3 hours;

2, above-mentioned medical material decocts with water twice, and 3 hours for the first time, 2 hours for the second time; Remove medicinal residues twice medicinal liquid merged, precipitate 12 hours, remove its supernatant liquid filtering, get medicinal liquid; Filtrate concentrates 18 hours, is concentrated into relative density and reaches 1.2-1.4;

The test example

Below further set forth the beneficial effect of medicine of the present invention by the test example,

1, physical data: clinical hospital: the 97th hospital of Xuzhou City, Jiangsu Province PLA:

Hospitalization 310 examples.

2, diagnostic criteria: press hepatitis diagnostic criteria.

3, criterion of therapeutical effect:

Produce effects: cardinal symptom disappears, liver, the corresponding retraction of splenomegaly, and YB, A, G, ALT recover normal;

Effectively: the cardinal symptom hepatosplenomegaly makes moderate progress, and it is normal that TB, ALT recover, and A raises, and G descends, but does not reach normal;

Invalid: cardinal symptom and hepatosplenomegaly are improved, and A and G do not have improvement, and TB and ALT do not recover normal or raise.

4, instructions of taking: with embodiment 1 medicine, every day 3 times, each 4 (every 0.45 gram).

5, clinical treatment result:

Produce effects: 71 examples are effective: 205 examples are invalid: 34 examples

Total effective rate: 89.03%

Claims

1, a kind of Chinese medicine for the treatment of acute, chronic hepatitis, liver cirrhosis is characterized in that it is made by following bulk drugs: