CN1733171A - Medicine, food used article for preventing and curing chronic diarrhoea and method for producing the same - Google Patents

Abstract

The invention provides a food product with medicinal effects for preventing and treating chronic diarrhea and its production process, which is prepared from Chinese medicinal herbs including root of pilose asiabell or ginseng, astragalus root, Indian buead as raw material. The production process comprises the preparation, extraction and application of organic and inorganic mixed solvents, normal temperature and high temperature step-by-step abstraction, as a result, the production process has the following advantages: substancially improved medicinal effect, extract quality and content, high extraction rate, short production cycle, less energy and water consumption, low cost of manufacture, no pollution by organic solvent. By using lactose to substitute easily absorbed starch and dextrin as absorbent and bulking agent, the drug release speed can be slowed down substantially, the drug effects can be prolonged, and the possible drug stimulation can be minimized.

Description

Prevent and treat chronic diarrhea dietotherapeutic product and manufacture method

Motherland's medicine and pharmacology, promptly with its good curative effect, low toxic and side effects and far away historical and global well-known Chinese medicine and pharmacy, its representative characteristics are exactly all mainly to take effective " hope, hear, ask, cut " common approach to observe various disease and patient's concrete presentation, with various all kinds of numerous and complicated diseases of correct differentiation, diagnosis and treatment and patient.Because this class understanding disease and patient's method system and comprehensive, thoughtful, diagnosis and treatment various disease and patient's first-hand clinical investigation data is in general just correct and reliable, that carries out on this basis then suits the remedy to the case, just can ensure that debating disease executing controls substantially again, add the fast development and the systemic outstanding achievement of modern Chinese medicine pharmacy, solved in many estrangement, the difficult problem of pharmacy of western medicine theory and practice aspect, reach and promoted many common recognitions, make between the two class medicine and pharmacology complementary; Although different Chinese medicine workers are not the same to same disease and patient's diagnosis and treatment power (time and ability) level, even have than big gap, but also be particular about " art is specialized in " day by day at tcm field, learn today that (specially) section constantly segments, add for a long time and practise medicine, informed experience and constantly accumulation, just can constantly produce distillation by the qualitative leap of quantitative change to qualitative change, even the stage that reaches " high degree " is also done fully and is obtained and be not rare, and except that some " difficult miscellaneous diseases ", numerous diseases and patient generally have the feature of intercommunities such as " things of a kind come together, people of a mind fall into the same group ", make and debate disease executing and control regular following, even if difficult miscellaneous diseases also are comparatively speaking, along with research deeply equally also can have rule to follow, so Chinese medicine can receive that " As the medicine took effect, the symptoms lessened " and toxic and side effects are little, effects such as no Drug resistance have been exactly very natural thing.So Chinese medicine and pharmacy comprises pharmacy of western medicine origin and flourishing countries and regions more and more widely in the whole world, more and more promptly obtain approval and application, it shows more and more outstandingly to contribution of human health life-prolonging and importance, market is also therefore extremely wide, even rising and the Chinese medical theory of China of exporting country of Chinese medicine appear, especially modern Chinese medicine science and technology and product, industry does not catch up with especially many developed countries in the world and geographic development speed, must try hard to catch up and should constantly keep domestic and international leading position and level, should be China's duty-bound corporation responsibility of each Chinese medicine worker and lofty mission.

Chronic diarrhea just has above-mentioned things of a kind come together, people of a mind fall into the same group intercommunity feature, generally all be transformed because of acute gastroenteritis, summer, greedy cool and living, cold, peppery food and beverage stimulated, or summer high temperature microbe easily breed, as equal susceptible disease such as edible microbial infection or rotten food, no matter and for common pilosity also, the usual health status quality of patient's large contingent all can fall ill; Especially colitis, the daily life diet is careless slightly as enjoying the cool summer, have some life a little, cold, the peppery maximum phase of an eclipse is to just having drunk some beverages, sometimes even only be to have drunk some water, or the stimulations such as thing of meeting tension pressure just can be fallen ill, and easily outbreak also very easily transfers chronic colitis to repeatedly, several months, several years, many decades and even cannot be cured all one's life, even even more serious exactissima diligentia daily life, under situation about stimulating without any outside risk factor, the disease still periodically approved for distribution and the state of an illness are not light equally: the abdominal pain diarrhea borborygmus, gas is directly scurried down, every day, defecation 4,5 times even more times, even serious interval is less than a few minutes half an hour, What is more says just outbreak of outbreak, stomachache is just anxious all to be difficult to stand and feel always not draw to seeming a second; Stool is long-term difficult be shaped in addition be water sample fully, more serious defecation is spurting, or dry stool, loose stool become periodically promptly good and then draw several the Heavenly Stems to draw several days loose stool after an action of the bowels again, bad then only draw several times and just draw loose stool several times behind the dry stool, and just the number of times of having loose bowels is far more than the number of times that draws dry stool, when more serious even rare with once also only doing earlier the back in just, or ten days first quarter moons are loose stool entirely, and the isochronous embarrassments such as pollution underwear unexpected out of control that are difficult to take precautions against of aerofluxus often occur.These problems not only cause above-mentioned abdominal pain diarrhea symptom, the more important thing is cause the nutrition of human body famine and easily be infested with all diseases and hydropenia even dehydration (arrange manyly and fast) and dizziness and blurred vision, the whole body so absorb few unable, feel sick, vomiting even bloody purulent stool, the intestinal perforation, the intestinal massive hemorrhage, toxic shock, life danger just easily takes place if fail in time to find with rescuing, as this moment, unfortunately having suffered from coronary heart disease again then very easily brought out myocardial infarction, these have all constituted very big threat and harm to health, should attract great attention and seek active drug and cure.

Western modern medicine has only the antiphlogistic and bactericidal of employing medicine to treat, but also can seriously kill intestinal beneficial bacterium simultaneously falls, not only very easily cause the function of intestinal canal disorder, deterioration develops, it is difficult to drag for a long time also can to make enteritis show effect further repeatedly, so risk is too big, lose more than gain proverb " what an awful nuisance, have only half-life for diarrhoea " can yet be regarded as its real picture and evaluation.Therefore, Chinese medicine just in time can use with its above-mentioned good drug effect and effect advantages such as toxic and side effects is little, no Drug resistance, thereby the ample scope for abilities has been arranged.

For solving this difficult problem, the present invention prevents and treats chronic diarrhea dietotherapeutic product and manufacture method is promptly arisen at the historic moment, with Radix Ginseng, Radix Codonopsis, the Radix Astragali, Poria, the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Semen Arecae, Fructus Mume, Rhizoma Atractylodis, Cortex Magnoliae Officinalis, Radix Rehmanniae Preparata, Fructus Schisandrae Chinensis Chinese crude drug is raw material, adopt the modern Chinese medicine Technology to process, debate disease executing according to Chinese medicine and control important ultimate principle and the flexible prescription of principle difference.

The Chinese medicine cardinal principle of foundation of the present invention is as follows:

Radix Ginseng sweet and slightly bitter taste, warm in nature; Strongly invigorating primordial QI, slake thirst and help produce saliva, transfer Rong Yangwei: a kind of medicine that is tonification vigour strength maximum.So-called vigour is exactly from congenital (in utero), is hidden in kidney, and the Yuanyang (gas) of circumfluence whole body, the gas of Kidney-Yin (blood, body fluid) can promote the function of all histoorgans of the vital organs of the human body, also are the fundamental driving forces of QI-blood circulation and nutrition whole body.So, every the five internal organs visceral-qi deficiency, the modesty disease such as be insomnia, diarrhea due to hypofunction of the spleen cold extremities, deficiency of the lung asthma breath is short, the deficiency of the liver palpitation with fear is peaceful, the weak bone flaccidity of suffering from a deficiency of the kidney is soft of throbbing with fear after one's own heart, and the collapse (pale complexion, cold extremities hidden pulse etc.) after all weak or big vomiting and diarrhoeas, massive hemorrhage all can use, the implication of Here it is strongly invigorating primordial QI; Because of the effect of promoting the production of body fluid is arranged, can treat the disease of diabetes and febrile disease body fluid being damaged; Generally speaking, Radix Ginseng can be transferred honor (blood) can support again and defend (gas), as long as how the disease of insufficiency of vital energy and blood can use.The Radix Ginseng valency is expensive, general how the replacement with Radix Codonopsis.

Radix Codonopsis is sweet flat; Invigorating the spleen and replenishing QI, slake thirst and help produce saliva: effect is similar to Radix Ginseng, only the efficacy of a drug more weak and can not be lastingly, generally deficient syndrome can be used for Radix Ginseng.Be usually used in that deficiency of both the splenic and pulmonary QI, lazy speech are losed heart, myasthenia of limbs, disease such as be off one's feed,

Radix Astragali sweet in the mouth is warm in nature; Receive the antiperspirant consolidating superficial resistance, ask skin ulcer granulation promoting, the deficiency of vital energy few: the energy invigorating QI to consolidate the body surface resistance has strengthening superficial resistance to stop perspiration, the especially excellence effect of internal injury of holder skin ulcer granulation promoting, so be usually used in the spontaneous perspiration of the deficiency of vital energy; Be the important medicine of QI invigorating, gas fills then hemapodium, thus can treat again because of insufficiency of vital energy and blood can not evacuation of pus or be difficult for the outer diseases such as ulcer sores closed up.Therefore it is the indispensable medicine of the treatment deficiency of vital energy.This product also has gas and diuresis in the elevate a turnable ladder, so can strengthen Radix Ginseng, Radix Codonopsis invigorating primordial QI and following diuretic drug effect, to the bad gastroenteritis of water of the present invention, food metabolism especially colitis and main aqueous thereof have loose bowels good control and and the very important impaired gastrointestinal organ's effect of reparation.Attached: the suitable processed with honey of tonify deficiency, outer disease should be given birth to usefulness.

Poria slightly sweet flavor, property are put down; The sharp key of eliminating dampness by diuresis: can promoting diuresis to eliminate damp pathogen, waterway, it mainly acts on is exactly to make to rest on that intravital water is wet to be drained from urethra, so to the bad gastroenteritis of water metabolism of the present invention especially colitis and main aqueous thereof the good prophylactic-therapeutic effect of having had loose bowels.

Rhizoma Atractylodis Macrocephalae sweet-bitter flavor, slightly warm in nature; Spleen invigorating stomach strengthening, antidiarrheal dehumidifying: the effect that mainly contains tonifying the spleen and stomach dampness.Can control because of having loose bowels that weakness of the spleen and stomach can not transmitting and distributing the fluids causes.Be applied to nausea discord diseases such as especially first anemia of pregnant woman of anemia of pregnant woman and common weakness of the spleen and stomach of pregnancy period, retention of water-damp in the body and general all more serious vomiting just, dizzy and two sufficient edema, so also have good antiabortive function.

Radix Paeoniae Alba sour in the mouth hardship, cold nature; Can receive and can mend, dysentery stomachache: it has the effect of convergence and replenishing YIN and blood, so energy stopping leak dysentery disease stomachache etc.

Semen Arecae acrid in the mouth hardship, warm in nature; The dispelling the stagnated QI parasite killing, eliminate the phlegm and relieve oedema or abdominal distension through diuresis or purgation: its decline circulation of qi promoting strength is bigger, and have pleasant, drive away entero-vioform effect, so be called the dispelling the stagnated QI parasite killing.In addition, distension and fullness of the chest and abdomen, the edema stayed for the expectorant water retention, and wait disease not to the utmost because of do not disappear having loose bowels of causing, dysentery, stomachache, defecation of food stagnation, all can treat.

The Fructus Mume sour in the mouth, warm in nature; The convergence lung qi, slake thirst and help produce saliva, can pacify dysentery: it has the effect of convergence lung qi, promoting the production of body fluid to quench thirst, controls the diabetes of the more than and deficiency of body fluid of the chronic cough of insufficiency of lung-QI, and can astringing intestine to stop diarrhea, control the chronic diarrhea chronic dysentery.

Rhizoma Atractylodis sweet-bitter flavor, warm in nature; The spleen strengthening and damp drying: it has drying damp and strengthening spleen effect.To epigastric distension and distress not easypro vomiting, watery diarrhea, and diseases such as wet heavy sensation of the body pain of outer power and prestige and joint aches are all suitable.

Cortex Magnoliae Officinalis bitter in the mouth, warm in nature; It is full that relieving distension is let out, the mental disorder dysentery, and its merit is slow: the full effect of loosing of therapeutic method to keep the adverse QI flowing downwards dampness is arranged, the asthma and cough that breast abdominal distention stagnates and the abundant expectoration lung qi must not descend that must not circulate to the wet resistance the intestines and stomach stagnation of QI, and the diseases such as dysentery of the damp-stagnancy stagnation of QI, it is rapid to be total to therapeutic efficiency.

The Radix Rehmanniae Preparata sweet in the mouth, slightly warm in nature; Kidney nourishing and blood enriching, beneficial marrow and benefitting semen, pitch-black beard and hair: be nourishing kidney, strengthening and nourishing marrow and essence and the important medicine of enriching blood, can control blood deficiency diseases such as the weak and giddy of the waist knee joint of the weak bone of suffering from a deficiency of the kidney, control early whitening of beard and hair senilism disease and can crow palpus hair color.

The Fructus Schisandrae Chinensis sour in the mouth, warm in nature; Promoting the production of body fluid to quench thirst, Jinsui River exhaustion: the nourishing kidney promoting the production of body fluid to quench thirst is arranged, the effect that treatment is quenched one's thirst.Kidney belongs to water, and the not enough water metabolism of kidney liquid is not normal and have loose bowels, so there is antidiarrheal etc. to restrain effect.

Radix Codonopsis, the Radix Astragali, Poria, the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Semen Arecae is principal agent and basic main formula, comprehensive coordinate is strengthened recovery gas, blood, water, the food metabolism is not normal, solve the dehydration of have loose bowels principal contradiction and generation fast, main harm such as malnutrition, also taken into account simultaneously muscle power, spirit, organ injury with in time repair as because of the powerful protection of tool of the impaired serious even forfeiture of inflammation with absorb the regeneration of gastrointestinal tract surface fine hair of nutrition and moisture content function and the thickening the hemorrhage and treatment of infecting the serious state of an illness of threat to life such as pus and blood of anti-perforation and recovery and (must lean on earlier the solution main body cause of disease promptly to have loose bowels of the gastrointestinal wall of attenuation to prevent and treat its infringement and extension thereof but will fundamentally address these problems, and recover the organ normal function to recover normal nutrition and energy supply level), cure acute onset as quickly as possible and prevent that effectively acute disease from transferring chronic disease to; Radix Ginseng, Fructus Mume, Rhizoma Atractylodis, Cortex Magnoliae Officinalis, Radix Rehmanniae Preparata, Fructus Schisandrae Chinensis is an accessory drugs, further strengthen principal agent and main formula and recover gas, blood, water, food not normal ability of metabolism and speed, being specially Fructus Mume controls the chronic diarrhea chronic dysentery and is beneficial to chronic disease and recovers, Rhizoma Atractylodis are strengthened Rhizoma Atractylodis Macrocephalae spleen invigorating dehumidifying and antidiarrheal efficacy, Cortex Magnoliae Officinalis is mobilized the lung power running stagnation of QI and is strengthened people (party) ginseng, Radix Astragali spleen reinforcing lung qi effect is rushed down to block water, it also is the application specifically and flexibly of Chinese medicine " this (stomach; intestinal; kidney master water metabolism) through disease outside (lung and Radix Ginseng; Radix Codonopsis; the Radix Astragali is to all) through controlling ", the kidney work hardening that Radix Rehmanniae Preparata and Fructus Schisandrae Chinensis are mobilized main water metabolism is antidiarrheal by normal discharge conduit urethra drain function, and Radix Ginseng is then transferred and strengthened all efficacy of drugs and all organ dysfunctions.The visual concrete state of an illness of these accessory drugss and the order of severity (the especially use of Radix Ginseng) be prescription flexibly, debates disease executing with raising and controls ability and therapeutic effect, specifically asks for an interview serial embodiment.

The manufacture method of product of the present invention is as follows:

1. the preparation of Chinese medicine extraction liquid

A. the choosing of raw material Chinese medicine is equipped with the concrete prescription by (patent statute invention protection domain can be not limited to embodiment) such as the different state of an illness such as embodiment, drink sheet type Chinese crude drug Radix Ginseng 1.5-3 part or Radix Codonopsis 3-5 part, Radix Astragali 1.5-3 part, Poria 2-4 part, Rhizoma Atractylodis Macrocephalae 1.5-3 part, Radix Paeoniae Alba 1.5-3 part, Semen Arecae 1.5-3 part, Fructus Mume 1-3 part, Rhizoma Atractylodis 1-3 part, Cortex Magnoliae Officinalis 1-2 part, Radix Rehmanniae Preparata 3-5 part, Fructus Schisandrae Chinensis 0.5-2 part joins in the nonmetallic surface such as containers such as fiberglass, enamel of belt stirrer, filter and water bath with thermostatic control heating (evaporation) device;

Preparation b. organic and inorganic mixed solvent is got the above ethanol of food stage (solubilized many be insoluble in the material of water and significantly improve drug effect) and adds the dilution of room temperature drinking water that to make ethanol (dense) degree be that alcohol content is the organic mixed solvent (mixed solution for extraction object Chinese medicinal ingredients material different liquids still can be considered solvent) with inorganic two kinds of solvent compositions of the sterilization type of 55-75% (V/V is a volume ratio), and alcoholic strength is lower than 55% or be higher than 75% equal difficulty and reach optimum extraction and sterilization effect;

C. use the described solvent of b to the raw material medicine extract with the described mixed solvent of b join a described added get in the container of whole Chinese crude drugs, addition is advisable for flooding Chinese crude drug fully, hermetic container soaked 20-30 minute, turn on agitator and with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, open filter, 50-100 eye mesh screen isolated by filtration medicinal residues and solution, the centrifugal medicinal residues of 1000-3000 rev/min rotating speed, medicinal liquid is incorporated isolated by filtration solution into, open heating (evaporation) device medicinal residues and medicinal liquid accurately are heated to 78-80 ℃ of ethanol boiling point (to reduce evaporation of water and distillation as far as possible) vaporization ethanol respectively, collect vaporization ethanol and the alcohol gas liquid coolant is changed into liquid ethanol recycling use with in advance online water-cooled condenser with the room temperature cooling water, ensure that extracting solution utmost point low organic solvent is the high-quality of alcohol content, used cooling water extracts water as preheating, these measure and ensures the low energy consumption of production and product, low water consumption, low-cost, and avoided the pollution of organic solvent to environment and product, the airtight f merge extractive liquid, that is equipped with of medicinal liquid is used, medicinal residues add the following d step and proceed to handle;

D. inorganic solvent water to medicinal residues proceed extract at room temperature will the medicinal residues after c handles join in the described empty of a, with the described preheating water of c flood fully, hermetic container room temperature (because of contain the few breeding of bacterium limited guarantee not putrid and deteriorated) soaked Chinese crude drug 20-30 minute, turn on agitator was with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, 150-200 eye mesh screen isolated by filtration medicinal residues and solution add the airtight f merge extractive liquid, that is equipped with of medicinal liquid the following e step with, medicinal residues and proceed processing;

E. inorganic solvent is proceeded to add (height) warm extraction to medicinal residues the medicinal residues after d handles is joined in the described empty of a, flood fully with the described preheating water of c, hermetic container, turn on agitator also stirs with 20-60 rev/min of rotating speed, add simultaneously (height) temperature (so the time contain bacterium may be than d for high) lower the temperature slowly naturally after 3-5 minute to boiling that (summer high temperature was lowered the temperature and can suitably be aided with the room temperature water-cooled too slowly in about 20-30 minute, the same recyclable described preheating water of c of incorporating into of cooling water) continues stripping and energy-saving and water-saving to 60-70 ℃ in order to pharmaceutical compositions, extract and must high temperature could propose and low temperature is not carried most material composition, and make and heat rapidly and evenly, reduce material damage and loss, with further raising drug effect and recovery rate, open filter, 150-200 eye mesh screen isolated by filtration solution and medicinal residues, discard medicinal residues behind the centrifugal medicinal residues of 1000-3000 rev/min rotating speed, medicinal liquid is incorporated isolated by filtration solution into and is equipped with f merge extractive liquid, usefulness;

F. extracting solution merges the medicinal liquid merging with c, d and e extraction, gets Chinese medicine extraction liquid.

2, the preparation of product of the present invention

With 1 described Chinese medicine extraction liquid, be concentrated to 25-30% weight ratio concentration with triple effect or multiple-effect vacuum evaporator and technology, adding lactose is the solution dry matter content that the concentration lifting is 35-40%, be spray dried into water content below 3%, products material of the present invention and water absorption is low and reduce fading of duration of storage and preserve easily, so storage life is that the commodity shelf life is long, economic worth is high; It is made type by the compression of Any shape (very easily) such as 0.3-0.5 gram/sheet, grain, ball, and being improved drug effect by the enteric protecting film to prolong slow-release time outward and reducing possible medicine stimulates, gets product.

The usage of product of the present invention, consumption and explanation:

Usage with 3 times for each person every day, preferably ante cibum edible, eat with a small amount of eliminating cold for resuscitation water and to avoid chewing food to improve drug effect but baby children answers porphyrize edible, consumption is advisable with the each 1-2 sheet of baby children, the each 2-3 sheet of child, the each 3-4 sheet of adult, very gentleness is without any side effects again because of belonging to the pure natural and the property of medicine, so need not segment crowd and age again.The lactose yield of taking in by product of the present invention is seldom, again an enteric slow release character, finally be degraded to the simple sugar glucose easily digested and assimilated and galactose, and transform lactose by the intestinal bacterial strain and become lactic acid by the intestinal Lactose enzyme, all can do utilization of energy for human body, so can not cause any lactose intolerance anaphylaxis, can also make human body adapt to lactose gradually on the contrary and reduce its anaphylaxis, these all with drink every day the milk amount big and for the lactose of the dissolved state of no slow release to cause that easily allergy has essential different.Lactic acid also the scalable intestinal microbial population balance and more help the recovery of intestinal beneficial bacterium strain such as bacillus bifidus etc., useful gastrointestinal function and be beneficial to the healing and the rehabilitation of disease.

Major advantage of the present invention is as follows:

1, flat, temperature or tepor of all property of medicine, be slightly cold, there are not heat, cold medicine, having no high fever medicine in Great Cold more, be that the property of medicine is gentle, this with regard to avoided gastrointestinal tract because of long-term chronic inflammatory disease originally very fragile and easily further irriate increase the weight of anaphylactoid function be subjected to again violent property of medicine loss or (with) stimulation, and this just Chinese medicine debate the principle that disease executing control and the imbody of marrow.

2, medicine variety is few and function is simple and clear, and the multiple state of an illness of prescription flexible adaptation and select medication properer has been opened up out Chinese medicine and debated disease and execute tool body content and range of application.

3, the main body common feature of enteritis is no patient crowd's branch, and pathogenic factor loses with state of an illness abdominal pain diarrhea QI and blood, sudden and morbidity is anxious, the state of an illness is heavy and highly consistent suddenly and very serious, controls difficulty for a long time and heals, so must obtain effectively treating as early as possible.Prescription silk silk of the present invention links closely, and the cause of disease, the state of an illness and formation effect promote mutually and reinforcement circulates benignly, and from solving its water, food metabolism not normal phenomenon stomach function regulating, intestinal, spleen, kidney, pulmonary function imbalance and recovering and strengthen their coordination ability system engineering roots between mutual and start with, event takes stopgap measures and effects a permanent cure and curative effect is remarkable fast, the healing cycle is short and cure rate is high (detailed aftermentioned clinical trial and curative effect and data introduction), has fundamentally captured this common frdquently encountered disease difficult medical problem.

4, all medical materials all are conventional varieties and have no side effect, so quality, the source is secure and aboundresources is cheap, product of the present invention can be consumed by vast general patient because of no patient crowd's branch event and obtain and afford to consume, and the realization new and high technology is served lofty aim for the most numerous common people.

5, innovate organic and inorganic mixed solvent and extract at room temperature and reclaim organic solvent and recycle molten and water-soluble substances and energy-conservation joint (cooling) water of Extraction oil with being beneficial to synchronously high-quality and high recovery rate, again with inorganic solvent and room temperature and high temperature combined extractive technique, scheme and technology, ensured extraction overall process asepticize, can carry substantially many to the greatest extent be insoluble in water or be insoluble in oil material and significantly improve drug effect and extract quality and content, and extraction ratio height, with short production cycle, energy-saving and water-saving, product cost is low, do not have (organic solvent) and pollute, its serial comprehensive advantage is traditional decocting and single with organic solvent or water or some other is because of expensive, highly difficult, the product of receiving single (fact proved and the generally acknowledged both at home and abroad compound composition extract of Chinese medicine than single composition extract good effect, this was exactly the essence and the inherent feature place of Chinese medicine originally and was determined by it), recovery rate low and short-term even long duration are difficult to that so-called modern Chinese medicine extractive technique that penetration and promotion uses is difficult to mention in the same breath.

6, become the favorable factor of the defective of China and Asia average 80% above population Lactose enzyme indigestibility absorption for want of (as milk) lactose into disease preventing and treating, the starch and the dextrin that adopt lactose to replace easily digesting and assimilating are made adsorbent and filler, can significantly slow down the medicine slow release speed and avoid taking treatment and the rehabilitation that traditional decocting Chinese medicine amount is very greatly and substantially the primary disease of water and favourable water metabolism imbalance, thereby significantly prolong the efficacy of a drug persistent period and improve curative effect and possible medicine irritation is relieved to bottom line.

Embodiment:

1, drinks sheet type Chinese crude drug Radix Codonopsis 3-5 part, Radix Astragali 1.5-3 part, Poria 2-4 part, Rhizoma Atractylodis Macrocephalae 1.5-3 part, Radix Paeoniae Alba 1.5-3 part, Semen Arecae 1.5-3 part, Fructus Mume 1-3 part, Rhizoma Atractylodis 1-3 part, Cortex Magnoliae Officinalis 1-2 part, by manufacture method of the present invention manufacture product and usage, consumption is edible; Be suitable for that first attack has watery stool but not have injection edible than severe disease feelings or following state of an illness rehabilitation and prevention of recurrence.

2, drink sheet type Chinese crude drug Radix Ginseng 1.5-3 part, Radix Astragali 1.5-3 part, Poria 2-4 part, Rhizoma Atractylodis Macrocephalae 1.5-3 part, Radix Paeoniae Alba 1.5-3 part, Semen Arecae 1.5-3 part, Fructus Mume 1-3 part, Rhizoma Atractylodis 1-3 part, Cortex Magnoliae Officinalis 1-2 part, Radix Rehmanniae Preparata 3-5 part, by manufacture method of the present invention manufacture product and usage, consumption is edible; It is edible to be suitable for first attack and injection watery stool severe disease feelings or following state of an illness rehabilitation and prevention of recurrence.This class patient transfers repeatedly morbidity to by acute, and organ and function have been subjected to comparatively grievous injury, must employ the Radix Ginseng transfer and coordinates all histoorgan potentiality and just can comparatively fast cure rehabilitation and prevention of recurrence.

3, drink sheet type Chinese crude drug Radix Ginseng 1.5-3 part, Radix Astragali 1.5-3 part, Poria 2-4 part, Rhizoma Atractylodis Macrocephalae 1.5-3 part, Radix Paeoniae Alba 1.5-3 part, Semen Arecae 1.5-3 part, Fructus Mume 1-3 part, Rhizoma Atractylodis 1-3 part, Cortex Magnoliae Officinalis 1-2 part, Radix Rehmanniae Preparata 3-5 part, Fructus Schisandrae Chinensis 0.5-2 part, by manufacture method of the present invention manufacture product and usage, consumption is edible; Be suitable for seriously spraying watery stool and food debris seldom or do not have and be that the critical state of an illness and the rehabilitation of water eats with prevention of recurrence substantially.In the most serious and tradition of this class conditions of patients, the general prognosis of western modern medicine is relatively poor as produced obstinate drug-fast bacterial strain and in intestinal very difficult healing such as preponderate, substantially all be to transfer repeatedly morbidity and chronic to by acute, organ and function have been subjected to grievous injury so each course of disease is all long and short at interval, rehabilitation is difficult, must employ Radix Ginseng and full class medical material with power, transfer and comprise that mainly fortune water, food and all histoorgans coordinate mutually, strengthen that potentiality just can be cured and progressively comparatively fast rehabilitation and prevention of recurrence for lung, spleen, kidney.

Test, effect and data and explanation:

Disease that product of the present invention is controlled belongs to common frdquently encountered disease so tool is extensively representative, the test patient especially very easily obtains in the test of torridity summer frequently-occurring disease time voluntary participation, product of the present invention is because of good effect and have no side effect and crowd's branch, so treatment cycle is short and cure rate is high, and make test be easy to just satisfactorily be finished, now further do following explanation (only for reference) under the prerequisite of necessary KNOW-HOW and business secret and please understand: totally 80 of the test patients at different sexes age allow keeping in Patent Law about situation, it is 4 groups that 20 people are divided into for one group, two groups are the treatment of antibiotics (transfusion adds oral) constant with traditional western modern medicine, in addition two groups are with products of the present invention and usages, the consumption treatment, the result is as follows: though the west, Chinese medicine effective percentage and cure rate are 100%, but taking a turn for the better is basic antidiarrheal (not passage of watery stools) onset time Western medicine group 10-24 hour, Chinese drug-treated group 3-5 hour, the defecation natural rate of interest is every day 1-2 time and stool basic forming onset time Western medicine group 1-2 day, Chinese drug-treated group 10 hours-1 day, cure and promptly defecate into Western medicine group 3-5 day finger-like time, Chinese drug-treated group 2-3 day, especially what deserves to be mentioned is that the healing back Western medicine group 15-20 that promptly leaves hospital has 7 people to recur back former prescription on individual diagnosis hospital therapy successively in day, relapse rate is up to nearly 20%, and Chinese drug-treated group is not found a people and is recurred further consultation, prove that product of the present invention only needs promptly short can curing substantially 2-3 day 1 course of treatment, this is that traditional Chinese medicine therapy is difficult to do and obtains, tracing it to its cause, we think and remove product curative effect of the present invention really than in the tradition, the western modern medicine curative effect is rapidly and outside lasting, be the dietotherapeutic product also with product of the present invention, after warning the patient to cure to be discharged from hospitals upon recovery, we should continue it as prevention and health care food and can take substantial connection for a long time, comprise that western modern medicine (12 person-times) cures to be discharged from hospitals upon recovery and in the above-mentioned time period, do not recur personnel because we pay a return visit (totally 28 person-times), majority is all adopted the suggestion of having accepted us, adhere to edible product of the present invention to some extent, and no one continues to take antibiotics, this is also from illustrating that on the one hand Chinese medicine and the prophylactic effect of product of the present invention are comparatively remarkable really, easilier be Chinese's institute's recognition and acceptance and putting into practice than the western modern medicine prevent disease, also be the more importantly concrete manifestation at mission and more bright following place of Chinese medicine, be worth showing great attention to evaluation.

Claims (3)

1, a kind of chronic diarrhea dietotherapeutic product of preventing and treating, it is characterized in that by Chinese crude drug Radix Codonopsis 3-5 part or Radix Ginseng 1.5-3 part, Radix Astragali 1.5-3 part, Poria 2-4 part, Rhizoma Atractylodis Macrocephalae 1.5-3 part, Radix Paeoniae Alba 1.5-3 part, Semen Arecae 1.5-3 part be principal agent, zero kind of optional Fructus Mume 1-3 part, Rhizoma Atractylodis 1-3 part, Cortex Magnoliae Officinalis 1-2 part, Radix Rehmanniae Preparata 3-5 part, Fructus Schisandrae Chinensis 0.5-2 part are to being accessory drugs all.

2, prevent and treat the manufacture method of chronic diarrhea dietotherapeutic product, its feature is as follows:

The preparation of A Chinese medicine extraction liquid

A. decoction pieces type Chinese crude drug Radix Ginseng 1.5-3 part or Radix Codonopsis 3-5 part are on the waiting list in the choosing of raw material Chinese medicine, Radix Astragali 1.5-3 part, Poria 2-4 part, Rhizoma Atractylodis Macrocephalae 1.5-3 part, Radix Paeoniae Alba 1.5-3 part, Semen Arecae 1.5-3 part, Fructus Mume 1-3 part, Rhizoma Atractylodis 1-3 part, Cortex Magnoliae Officinalis 1-2 part, Radix Rehmanniae Preparata 3-5 part, Fructus Schisandrae Chinensis 0.5-2 part joins in the nonmetallic surface such as containers such as fiberglass, enamel of belt stirrer, filter and water bath with thermostatic control heating (evaporation) device;

Preparation b. organic and inorganic mixed solvent is got the above ethanol of food stage and is added the dilution of room temperature drinking water and makes the mixed solvent that alcoholic strength is the organic and inorganic two kinds of solvent compositions of the sterilization type of 55-75%V/V;

C. use the described solvent of b to the raw material medicine extract with the described mixed solvent of b join a described added get in the container of whole Chinese crude drugs, addition is advisable for flooding Chinese crude drug fully, hermetic container soaked 20-30 minute, turn on agitator and with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, open filter, 50-100 eye mesh screen isolated by filtration medicinal residues and solution, the centrifugal medicinal residues of 1000-3000 rev/min rotating speed, medicinal liquid is incorporated isolated by filtration solution into, open heating (evaporation) device medicinal residues and medicinal liquid accurately are heated to 78-80 ℃ of vaporization of ethanol boiling point ethanol respectively, collect vaporization ethanol and the alcohol gas liquid coolant is changed into liquid ethanol recycling use with in advance online water-cooled condenser with the room temperature cooling water, used cooling water extracts water as preheating, and the airtight f merge extractive liquid, that is equipped with of medicinal liquid is used, medicinal residues add the following d step and proceed to handle;

D. inorganic solvent water to medicinal residues proceed extract at room temperature will the medicinal residues after c handles join in the described empty of a, with the described preheating water of c flood fully, hermetic container soak at room temperature Chinese crude drug 20-30 minute, turn on agitator was with 20-60 rev/min of rotating speed agitating solution and Chinese crude drug 20-30 minute, 150-200 eye mesh screen isolated by filtration medicinal residues and solution add the airtight f merge extractive liquid, that is equipped with of medicinal liquid the following e step with, medicinal residues and proceed processing;

E. inorganic solvent is proceeded to heat to extract to medicinal residues the medicinal residues after d handles is joined in the described empty of a, floods fully with the described preheating water of c, hermetic container, turn on agitator also stir, are warmed to simultaneously boiling with 20-60 rev/min of rotating speed and slowly lower the temperature about 20-30 minute to 60-70 ℃ after 3-5 minute naturally in order to pharmaceutical compositions continuation stripping, open filter, 150-200 eye mesh screen isolated by filtration solution and medicinal residues, discard medicinal residues behind the centrifugal medicinal residues of 1000-3000 rev/min rotating speed, medicinal liquid is incorporated isolated by filtration solution into and is equipped with f merge extractive liquid, usefulness;

F. extracting solution merges the medicinal liquid merging with c, d and e extraction, gets Chinese medicine extraction liquid.

The preparation of B product

With the described Chinese medicine extraction liquid of A, be concentrated to 25-30% weight ratio concentration with triple effect or multiple-effect vacuum evaporator and technology, adding lactose is the solution dry matter content that weight ratio concentration promotes and is 35-40%, being spray dried into water content must raw material 3% below; Raw material is pressed 0.3-0.5 gram/sheet, grain, ball compression moulding, got product by the enteric protecting film outward.

3, prevent and treat the purposes of chronic diarrhea dietotherapeutic product, be used for producing control diarrhoea medicine and food host, consumption needs by ordinary production; As control diarrhoea medicine and food, usage for each person every day 3 ante cibum edible, eat with a small amount of eliminating cold for resuscitation water and to avoid chewing food but baby children answers porphyrize edible, the each 1-2 sheet of consumption baby children, the each 2-3 sheet of child, the each 3-4 sheet of adult.