CN1712063A - Compound Chinese medicinal preparation for treating chronic effort syndrome - Google Patents

Abstract

A Chinese medicine for treating chronic exhaustion syndrome is prepared from 52 Chinese-medicinal materials including red ginseng, astragalus root, liquorice root, Chinese angelica root, etc.

Description

A kind of Chinese traditional compound medicine for the treatment of chronic fatigue syndrome

One, technical field:

The present invention relates to a kind of compound Chinese medicinal preparation, be specifically related to a kind of Chinese traditional compound medicine and preparation method for the treatment of chronic fatigue syndrome.

Two, background technology:

Chronic fatigue syndrome also claims confirmed fatigue, subhealth state, yuppie flu and immunologic dysfunction syndrome.

The clinical manifestation of chronic fatigue syndrome is mainly inexplicable lasting or in-and-out serious fatigue, and is not that motion causes, can not alleviate by lying up, and cause the obvious decline of work, study and social activity ability and competitiveness; Simultaneously with slight fever; The lymphadenectasis of having sore throat; Muscular tension is low, and muscular flaccidity is ached and be unable; Arthralgia; Headache; Parahypnosis.As drowsiness or insomnia; Dizzy, nauseating; Diarrhea and constipation are alternately; Spirit depressing; Weight increase or alleviate obviously; Night sweat; Anorexia nervosa; Heart beating is overrun; Arrhythmia; Premature beat; Deficiency of QI with disinclination to talk, apathetic expression, absent minded, disturbance in thinking, hypomnesis.Neural mental symptom and immune system abnormality etc.Health check-up and Routine Test Lab inspection do not have great discovery, and increasing with Epstein-Barr virus antibody [EBA] titre often checked in the immunization experiment chamber.This disease was suggested (one piece of report about chronic ebv infection) from 1988, determined the existence of primary disease in 1993 in the world, then the physician of various countries, the whole world has carried out a large amount of research to chronic fatigue syndrome, but does not find to hold the paathogenic factor of the opposite sex so far.Because the etiology unknown of chronic fatigue syndrome, pathogeny is unclear as yet, therefore, modern medicine does not have special Therapeutic Method to chronic fatigue syndrome, mainly is symptomatic treatment, and common drug has Energy mixture (to replenish carnitine, the fatty acid of human body necessity, magnesium ion), vitamins is (as V-B6; V-c; V-E), antiviral drugs, antidepressant and anxiolytic drugs, and analgesic and some antipyretic.Chronic fatigue syndrome has become modern medicine, common property of environmental medicine, multiple disease, and sickness rate increases gradually.Interrelated data shows that the sickness rate of chronic fatigue syndrome all is the trend that rises year by year in worldwide.Britain, the U.S. have 20%, 14% male and 25%, 20% women always to feel tired respectively; In China, among the white collar class more than 40 years old, the overweight person's of health confirmed fatigue situation is especially outstanding.Chronic fatigue syndrome mostly occurs in the higher young crowd of socioeconomic status, and medical worker particularly nurse's incidence rate is higher than general crowd.

Three, summary of the invention:

Technical problem to be solved by this invention is:

At having present situation and problem in the background technology, the inventor is according to the classical Chinese medicine theoretical essence, have on the basis of applied system research of efficacious prescriptions medicine to chronic fatigue syndrome disease, card, the cause of disease, pathogenesis, method of treatment and safely,, use in the sweet temperature compensation, supplementing QI for promoting the production of body fluid, hold up spleen reinforce the kidney, the reduce phlegm stasis of blood, clearing away damp-heat method and Chinese traditional compound medicine treatment chronic fatigue syndrome, with it clinical significant curative effect of having obtained, thus the blank of having filled up this field Basic Theories of Chinese Medicine research and having treated.

The theoretical basis of Chinese traditional treatment chronic fatigue syndrome:

Chronic fatigue syndrome belongs to the category of Chinese medicine " asthenia ", " deficient ", " fever due to internal injury ", " melancholia ", " blood stasis symptom ", " phlegm syndrome ".

Theoretical basis of the present invention and foundation are as follows:

1. chronic fatigue syndrome tcm causa morbi research

Chinese medicine thinks that chronic fatigue syndrome belongs to one of traditional Chinese medical science five kinds of over strain, i.e. will labor, think of labor, the impairment of the heart caused by overstrain, care-laden and overworked and fatigue.(Sui. Chao Yuanfang (550-630 A.D.) " General Treatise on the Cause and Symptoms of Diseases ").All " labor " must be because of in void, and fictitious pole must become " labor "." element is asked. the logical deficiency and excess opinion of commenting " descended a very generalized definition for " void ": " lack of vital essence resulting in deficiency syndrome ", empty person: negative and positive, QI and blood, Ying Wei, spirit, bone marrow, deficiency of body fluid are also; Damage person, outer and skin, arteries and veins, meat, muscle, bone, interior and lung, the heart, spleen, liver, diabetes involving the kidney decreases is also.Become labor person, call with the passing of time deficiently, linger on and do not heal, form five kinds of over strain, six types of severe debility disease, seven kinds of impairments also.(Wu Qian etc. " the full mirror of doctor ancestor. miscellaneous diseases heart method knack ").More than the explanation various symptoms and signs of deficiency is the basic pathogenesis that causes fatigue syndrome.Void, damage, labor, the utmost point are that confirmed fatigue is levied four chronic developmental stage." difficult warp. 14 difficulties " create saying of " five serious conditions of leprosy involving five ZANG-organs ", the light and heavy degree and the nobility that set forth the loss of primary disease interior-deficiency develop: " one decreases in fur, and skin gathers and hair dropped; Two decrease in blood vessels, and blood vessels are empty few, can not be flourish in the vital organs of the human body also; Three decrease in muscle, wasting, and diet can not be skin; Four decrease in muscle, and muscular atonia can not be held from receiving; Five serious conditions of leprosy involving five ZANG-organs decreases in bone, and the atrophic debility of bones can not arise from bed." this patient's condition of in fact having pointed out chronic fatigue syndrome develops, be from top to bottom: lung → heart → spleen → liver → kidney, on down then in contrast.(chronic fatigue syndrome internal organs Damage Evolution), in sum, chronic fatigue syndrome QI and blood, negative and positive, internal organs, as follows along contrary evolution process: gas, blood deficiency → negative and positive void → QI and blood, deficiency in both YIN and YANG → elder generation's one, two deficiency of five ZANG-organs damage → a plurality of internal organs is deficient → the spleen damage of suffering from a deficiency of the kidney.Spleen kidney one loses → and by empty and decrease → caused by damage the generation of chronic fatigue syndrome → by Lao Erji → vigour depletion, cloudy sun to the greatest extent dies → and the gesture difficulty retrieves.The reason that (annotate: symbol → expression causes) causes confirmed fatigue to be levied is most complicated, mainly contains body constitution, life, disease three factors but study carefully its most outstanding factor.

1.1 physical factors: body constitution is exactly the competencies that human body has.Body constitution is determining the tendentiousness of human body to the susceptibility of paathogenic factor and pathogenesis, syndrome.What the quality characteristic that forms the people was played a decisive role then is natural endowment.As: lose to support in father and mother's body void, nausea deficiency or the tire, just before giving birth impaired etc., make internal organs strong, insufficiency of vital energy and blood, life is not prosperous, causes the body constitution of shape gas weakness, is easy to suffer from all diseases and eventually to deficient and cause chronic fatigue syndrome.When emphasizing the decisive action of natural endowment in pathological process in " vigour living or death opinion ", the Xu Ling tire says: " in it is given birth to, existing fixed here the branch ".Gong Juzhong " red stove point snow " also points out: " a little less than the natural endowment element, the kidney of working with one's mind again ", cause tired importance to forming deficient, all be experience have speech.

In addition, the people has bad physiques, have again from decline, senilism with cross decline different, also be the physical factors of easily suffering from confirmed fatigue.Human body is called from declining not because of the process of the influence naturally-aged of objective factors such as disease." element is asked. the big opinion of YIN YANG classification of natural phenomena " and cloud: " ... man-year 40 and half of YIN QI consumed.Nian Liushi, impotence, extreme exhaustion of QI, dysfunction of the nine orifices, deficiency in the lower and excess in the upper, running nose and shedding tears simultaneously." point out the decline naturally with advancing age and gradually of internal organs negative and positive, this is human vital process's a natural phenomena.Because from the appearance that declines, viscera life goes down, the healthy energy interior-deficiency, weakened defensive QI then subjects to the exopathogen invasion.Human body aging course occurred in 40 years old in the past, was called senilism; Its aging degree more very was called and declined after 40 years old." senilism " head see " element is asked. the big opinion of YIN YANG classification of natural phenomena " " can know seven harmful methods and eight favorable techniques in sexual life, then the two is adjustable, does not know to use this, and then early the stages of senility is also ".Senilism, crossing and to decline and decline equally certainly, be the physical factors of formation chronic fatigue syndrome, and the process of human senility is more quickened in the generation of chronic fatigue syndrome.

1.2 life factor: life factor refers to inappropriate life style, and this is a key factor of suffering from chronic fatigue syndrome.

1.2.1 chamber does not save, and consumes Kidney-Yin.The ancient medicine man thinks that excess of sexual intercourse is the major reason that causes fatigue syndrome." Jing Yue's complete work. assorted card plan, deficient " point out: " the excessive person of sexual urge becomes strain more " Zhu Danxi " Further Discourses on the Properties of Things " points out: " it is aroused in interest that then fire is also moving mutually, moving then smart oneself walk, fire is in unison and is risen mutually, though not intersection also undercurrent let out ".Give up completely to natural impulse, consume Kidney-Yinly, long-pending little one-tenth decreases, and long-pending the damage becomes to decline, and forms fatigue syndrome.

1.2.2 overstrain, feelings will internal injury.The uneven allocation of work and damage body.Impairment of blood by looking for a long time, prolonged sitting injuring the muscles, prolonged walking injuring tendons, prolonged standing injuring bones, excessive rest on bed impairing QI." precious family four will " points out: " ' the refreshing machine of bent fortune is then worked with one's mind, and conscientiously considers then impairing the liver, and unexpected the mistake thought the then impairment of the spleen, melancholy labor lung then when anything crops up, sexual urge is the labor kidney excessively then "." element is asked. the big opinion of YIN YANG classification of natural phenomena " and so-called " excessive anger impairing the liver ", " excessive joy impairing the heart ", " melancholy impairing the lung ", " excessive fear impairing the kidney ", " the frightened gallbladder of hindering " can cause the internal organs loss, and manner is crossed consumption and is caused fatigue syndrome.

1.2.3 eating and drinking without temperance, daily life is not normal.Eating and drinking without temperance comprises eating and drinking too much at one meal, long-term hungry and badly has a liking for popular monophagia etc.The eating and drinking too much at one meal impairing the spleen and stomach, then spleen and stomach function is weak day by day for a long time, and the internal organs QI and blood is lost in moistening to support with the passing of time and is decreased by void, satisfies into fatigue syndrome.Long-term hunger, biochemical passive, certainly will cause the health loss, little to nourish by foodstuff essence because of viscera, QI and blood leans on essence of water and grain to change life.As for having a liking for popular monophagia, " element is asked. the five internal organs generate a piece of writing " says in that " institute of the five tastes hinders " time is discussed: " hereat polyphagia is salty, and then arteries and veins is wept and variable color with fixed attention; Polyphagia hardship, then lustreless skin and hair is dialled; Polyphagia suffering, then muscular contracture and paronychia; Polyphagia acid, then meat Zhi And craeked lip; Polyphagia is sweet, then osteodynia and deal with ".Illustrate that monophagia is can damage shape dirty and may cause fatigue syndrome.On the scoop, damage is unit very, and a large amount of smokings consume the impairing the lung gas, all belongs to cause the empty Lao Zhiyin of one-tenth.Aspect daily life, not work and rest rationally, Chang Yi causes the damage of shape gas.As work in long-term late into the night, easily consume body the moon, lying on bed for a long time the is drowsiness also energy loss gas of overtaxing one's nerves causes that internal organs are not flourish, deficiency of qi and blood, weakened defensive QI, the exopathogen invasion gradually becomes deficient and causes fatigue.

1.3 disease factor: all sick mistakes are controlled or wrong treatment, loses after being ill in conditioning, and the internal injury of being overworked for a very long period, body and the spirit is crossed consumption, and essence and blood is empty few, internal organs hypofunction, insufficiency of generating and transforming QI and blood; Phlegm retention, depressed, blood stasis are detained for a long time, and not go also be to cause therefore one of fatigue.

2. the low grade fever etiology and pathogenesis of chronic fatigue syndrome research:

The low grade fever of chronic fatigue syndrome belongs to the category of traditional Chinese medical science fever due to internal injury.The definition of fever due to internal injury: with the internal injury is the cause of disease, visceral dysfunction, and it is the heating of basic pathogenesis that negative and positive of qi and blood loses void, is called fever due to internal injury.Show as low grade fever more clinically, but also can show as hyperpyrexia sometimes.General onset is more slow, and the course of disease is longer.

Fever due to internal injury is different with fever caused by exogenous pathogens, and why fear of cold or heating is caused by the imbalance of YIN and YANG of body." element is asked. the regulating menstruation opinion " in have: the record of " insufficiency of YANG bringing about exterior-cold symptoms, deficiency of YIN bringing about interior heat, yang predomination generating heat, excess of YIN bringing about interior-cold syndrome ".Have again: " is deficiency of YIN given birth to interior-heat how? fork uncle day: " overstrain to some extent, the shape weakness of QI is few, and essence derived from food is not contained, and the part of the body cavity above the diaphragm housing the heart and lungs is not all right, and pylorus is obstructed, gastric qi heat, steam is smoked in the heart, so interior-heat." the said here deficiency of YIN gives birth to interior-heat and be meant that overstrain can consume the moon of feeling frustrated, and influenced the digestive function of taste, causes heat from interior life, illustrated that overstrain can cause imbalance of YIN and YANG and generates heat.

" element is asked. vital QI of the body connecting with natural QI opinion " in also have: " the yang-energy person bothers then and opens, insufficiency of essence ".Point out the yang-energy of the person, if under the situation of excessively bothering, will nervous high Sheng, yang-energy is promptly right, and nervous high Sheng, cloudy essence also can be exhausted, illustrates that bothering equally also is to cause imbalance of YIN and YANG, also can cause certainly generating heat.

Chronic fatigue syndrome patient vim and vigour weakness, deficiency in both YIN and YANG has overstrain slightly, then heatable (a little less than the human blood feeble QI of asthenia, deficiency in both YIN and YANG, Xiao Lao are then given birth to heat, and Re Yinlao and giving birth to is so an exopathogenic heat also " asthenia exopathogenic heat time ").

Li Dongyuan " Treatise on the spleen and stomach " has improper diet and overtiredness to hinder, and begins to be saying of pining for, and thinks: diet, overstrain, seven emotions etc., lose in adjusting, and impairing the spleen and stomach, the vigour of taste is sunk, cause the fire mutually of Liver and kidney to be offed normal, superior taste disturb pericardium, so-called: " YIN-fire ", this fire and vigour incompatibility, YIN-fire are contained then vigour and are weakened, and vigour weakens that then deficiency of spleen-QI and stomach-QI is more obvious, thereby causing fever due to internal injury, this is meant the deficiency of spleen-QI and stomach-QI heating.And treat with the BUZHONG YIQI TANG that embodies this Therapeutic Principle of ascending YANG and invigorating QI, the ascending YANG and invigorating QI method is played an important role in the treatment fever due to internal injury.This is the method (make taste get the power of lifting, then deficiency-heat is not controlled from moving back) of famous relieving high fever with drugs of sweet flavor and warm nature.

Xue Lizhai payes attention to the relation of taste and kidney, thinks: " very essence is closed and life, is that the people also borrows spleen soil with life, the treatment fever due to yin deficiency, and happiness is towards using BUZHONG YIQI TANG, and sunset is used LIUWEI DIHUANG WAN, the internal organs negative and positive during with the conditioning fever due to internal injury.

" Jing Yue's complete work. cold and heat " to the cause of disease of fever due to internal injury, the detailed argumentation of contrasting: the heat of internal injury then has because of the diet person of causing, have because of the overstrain person of causing, have, have because of the seven emotions person of causing because of the wine and women-sensual pursuits person of causing, have because of the pharmaceutical chemistry person of causing, have, have because of the deficiency of YIN person of causing because of crossing the warm person of causing.Some performances are also arranged on pathogenesis, as " Jing Yue's complete work. fire syndrome " say: " yang deficiency person also can generate heat, and loses with this Yuanyang to exhaust, and Gui Yuan is not for fire ", in treatment " Jing Yue's complete work. cold and heat " says: " the hot person of the deficiency of YIN should strengthen water to put down it; The hot person of unrooted should be fiery to train it "

Clearly. Li Yongcui " card is controlled and converge to be mended. heating " think heating except that diseases caused by exogenous pathogenic factor, overstrain, labor color, the stagnation of QI, fire stagnation, get ill from overeating, get sick from drinking too much wine, hold under the arm the stasis of blood, hold up expectorant, sore etc. all can cause heating.And with heating be divided into the deficiency of YIN, yang deficiency, the deficiency of vital energy, blood deficiency, stagnated fire, get ill from overeating, phlegm syndrome, blood stasis, sore etc., help to go deep into dialectical opinion and control.

Fever due to yang insufficiency is mentioned: " water-cooled of suffering from a deficiency of the kidney, fire do not return through, parade in outer and heating person, spontaneous perspiration is not appointed wind and cold ... should use eight flavor ball directing fire to its sources, what is called is crouched its bandits lair and recruited it, and promptly nourishing renal yang to restrict excessive yin is to disappear be shaded or hidden for foliage also.”

Chronic fatigue syndrome is because of overworked, due to the drinking and eating irregularly, causes deficiency of spleen-QI and stomach-QI, thereby causes heating.Its pathogenesis is: or be deficiency of vital energy outward dispersion of deficient YANG, or be deficiency of vital energy YIN-fire upper punch, and or be deficiency of vital energy weakened defensive QI, battalion defends and becomes estranged.As " Jing Yue's complete work. fire syndrome " say: " and this genus of gas sun, YANG QI deficiency, cold originating from the interior then, cold originating from the interior then sun do not have institute and comply with, and floating loose in outside, be the asthenic fire pseudo-heat meaning also.”

" Treatise on the spleen and stomach. improper diet and overtiredness is hindered the beginning for pining for opinion " says: " YIN-fire is taken advantage of its soil for deficiency of spleen-QI and stomach-QI, the then dirty kidney of taking advantage of ", " depletion of YANG is defended with Hu Qiying, does not then appoint wind and cold, is living cold and heat.”

The deficiency of spleen-QI and stomach-QI heating with the passing of time also can cause YANG deficiency of the spleen and stomach, becomes fever due to yang insufficiency.Stagnation of QI heating: depressed emotion, stagnated QI transforming into fire, or angry excessive, liver-fire is interior contains, so that heating, all claims the fire of five will.Jing-Yue Complete Works thinks that stagnation of QI heating is the deficiency of YIN, and " hindering in seven emotions is hot person, always belongs to kidney-YIN being deficient, so pathogenic fire is easily vehement." pent-up of feelings will is proposed, can cause the body deficiency of YIN and cause heating.The smart main pathogenesis that generates heat for the stagnation of QI of strongly fragrant and fire-transformation and consumption impairment of YIN.Fever with blood stasis: blood stasis stops amassing in body, makes QI and blood obstructed, and battalion defends to stop up and holds back, and causes heating.Illustrate that QI and blood is obstructed, it is also therefore not all right and generate heat to defend gas." Principle and Prohibition for Medical profession. the asthenia door. the asthenia opinion " say: " blood stasis is then flourish empty, and flourish void is then generated heat ", point out that fever with blood stasis is also irrelevant with blood deficiency.

Fever due to deficiency of blood: the prolonged illness heart-liver blood deficiency or insufficiency of the spleen can not hemopoietic, or various blood disorder chronic blood loss is too much, so that deficiency of nutrient QI and blood.And its this genus is cloudy, the moon then excess of YANG that declines, thereby cause heating.

Damp-stagnancy heating: about the strongly fragrant and heating due to the heating of damp, interior the wounded is caused by insufficiency of the spleen, the taste YANG QI deficiency, and inability of food and drink to be digested and transported, water-damp retention, then strongly fragrant for a long time and heat-transformation causes the heating of internal injury damp-stagnancy." book on Chinese herbal medicine is stated hook unit ": " it is in the majority that damp and hot disease of the person thought in examination, disobeys suitablely as seven emotions, exhaustion due to sexual indulgence, food and drink, and forced labour is excessive, hinders wherein gas, with tired vigour, causes the cloudy big damage of spleen, can not be stomach Xingqi body fluid person, He Kesheng number.”

From above etiology and pathogenesis as can be seen, the deficient heating that causes of negative and positive of qi and blood is deficiency syndrome, the stagnation of QI, blood stasis, the caused heat of damp-stagnancy are excess syndrome, but these excess syndromes often cause the further imbalance of internal organs yang blood and qi, cause the situation of vital QI being weakened and pathogen being violent, so that the low grade fever of chronic fatigue syndrome is touching, does not heal for a long time.

For its low grade fever, can not see that heat brings down a fever, early throws bitter cold, throws off restraint in sweet cold and damp-stagnancy heating and can not think the deficiency of YIN by mistake, and with soft and moist sticky cloudy medicine, otherwise hold back evilly in interior, love heresy in the lining, cause the gesture of fixed intangibility, often cause the low fever difficulty to be moved back.Will be at the pathogenesis of heating, treating is the cardinal principle of treatment fatigue syndrome fever due to internal injury.Characteristics according to chronic fatigue syndrome card marquis adopt in the sweet temperature compensation, supplementing QI for promoting the production of body fluid, and warming and recuperating the kidney-YANG, dispersing the stagnated live-QI to relieve the stagnation of QI, blood circulation promoting and blood stasis dispelling, the removing dampness heat clearing away is the Therapeutic Principle of treatment chronic fatigue syndrome low grade fever.

3. chronic fatigue syndrome

Depression and mental symptom, the cause of disease, pathogenesis research

Depression is not only the low tide of psychology, disorder especially.Secular low tide depression can cause hydroxytryptophan, adrenaline secretion imbalance, makes brain function generation obstacle, as untimely treatment, just can cause depression.The symptom of depression: lonely, pessimistic, movable minimizing, appetite descend and sleep disorder.It is unhappy often to be nervous, depressed, always suspects and oneself suffers from incurable disease.This moment, people's personality, interest changed, and can't break away from emotion and emotion misery.Digestion and hypersecretion produce to be felt sick, symptoms such as vomiting, stomachache, abdominal distention and diarrhea.

Modern medicine is thought: behind heavy psychological burden or secular psychentonia, the weakening of nervous function occurs, with tangible anxiety reaction and various body sense of discomfort, just become neurosis.Confirm according to the study: disease caused by mental factor with autonomic imbalance and endocrine variation as its physiological foundation.

Depression belongs to Chinese medicine " melancholia ", " phlegm syndrome ", " syndrome of blood stasis " category.Chinese medicine is said strongly fragrant, and two kinds of broad sense and narrow senses are arranged.Generalized strongly fragrant, comprise strongly fragrant due to the factors such as exopathogen, feelings will, before the gold dollar opinion strongly fragrant most genus this.Narrow sense strongly fragrant is meant that not relaxing with feelings will is the cause of disease, is the strongly fragrant of basic lesion with the depression and stagnation of QI, and promptly feelings will is strongly fragrant, after the Ming Dynasty opinion strongly fragrant, be main contents promptly with the strongly fragrant of feelings will.That strongly fragrant word has is long-pending, implication such as stagnate, pent up.Melancholia definition: melancholia is many not to be relaxed by feelings will, depression and stagnation of QI and causing a disease.With feel depressed, full vexed, the distending pain over the hypochondrium of irritable emotion, chest or irritability desire to cry, or disease such as to block if any foreign body in the pharynx be cardinal symptom.

The cause of disease of melancholia is a feelings will internal injury.(bright Xu Chunfu " doctor system at all times. the melancholia door " says: " strongly fragrantly do not relax, satisfy into pent-up, promptly strongly fragrant the sick multiterminal of change for seven emotions).But whether feelings will internal injury causes melancholia, except that also with the situation of body itself extremely close relation being arranged relevant with the intensity of direct stimulation and the time length that continues.As Sun Yikui " pearl in red water. Yu Men. strongly fragrant " say: " people of the void of being always or usually as specified, in case thing do not comply with one's wishes, the vertigo, spirit is deficient, muscle withers out of breath, have like deficiency syndrome, earlier when dissipating depression of QI pleasant, its sick spontaneous recovery." " miscellaneous diseases source and course rhinoceros candle. all strongly fragrant sources and courses " says: " and Zhu Yu, the visceral-qi disease also, its script is dark in pondering over, a little less than the more double visceral-qi, so the diease occurrence of six kinds of stagnation-syndromes is here.The six kinds of stagnation-syndromes person: gas, blood, wet, heat, food, expectorant are also.Illustrate a little less than the body visceral-qi, the plain void of body constitution be strongly fragrant disease morbidity intrinsic factor (shake of the heart resulting from excessive sorrow and melancholy, shake of the heart leading to shakes of all ZANG FU-organs " Ling Shu Miraculous Pivot or Divine Axis. mouthful ask ").

The melancholia pathological change and the heart, liver, spleen have substantial connection (emotional stress, the heart is become homeless foster; Anxiety and rage, depression of liver-QI, sorrow is pondered over, spleen loses and hikes).Melancholia just sick body is real, and pathological changes is based on the stagnation of QI, often hold concurrently blood stasis, fire-transformation, expectorant knot, dyspepsia etc., how true card.Prolongedly do not heal, then Sthenia is transforming into asthenia, with the difference of the internal organs and the loss negative and positive of qi and blood of its influence, and forms the different lesions of the heart, spleen, liver, deficiency of the kidney void.Say as (" Lei Zheng Zhi Cai, melancholia "): " that rises in the seven emotions is strongly fragrant, at first feels frustrated, and continuing to reach blood, is into labor eventually ", chronic fatigue syndrome clinically, simulataneous insufficiency and excessive, and from the beginning of promptly because of QI and blood, the negative and positive that consume impairment of ZANG FU-organs show as deficiency syndrome person, also morely see.

Chronic fatigue syndrome is to be caused " blood stasis symptom " by feelings will internal injury.Since emotional stress, shilling disorder of QI.Exist substantial connection between the QI and blood, so feelings will internal injury causes on the basis of the stagnation of QI or the deficiency of vital energy, can further form qi depression to blood stasis or blood stasis due to qi deficiency, as anger QI rising in reverse order then, the circumfluence that influences QI and blood is passed unimpeded and is formed blood stasis.The Yu Ze stagnation of QI is again just sickly then prolonged and blood system for a long time at edema caused by disorder of QI, forms qi depression to blood stasis, and venation block is so Shi Zhiyan strongly fragrant wound of a specified duration in leaf sky is used " a surname promote blood circulation network method " more." Elementary Medicine. stomachache " says: " pain due to blood stasis has normal place, or is worried against strongly fragrant and get, " and cure thorough. blood-retention " also say: " its people or overstrain, or fall and pounce on, or sprain and contusion, or disgruntled all are enough to hinder its blood and stop holding into the stasis of blood.Saying of the pathogen usually intruding into collateral in protracted disease that Ye Tianshi advocates, the pathogenesis that includes blood stasis due to qi deficiency be interior, as " read to cure random notes. manufacture biochemical opinion " spell out: " deficiency of vital energy is not enough to push away blood, and then blood must have the stasis of blood.

The normal operation of blood except that the promotion that relies gas, the delivery of the body fluid of still needing, Zhou Xuehai likens the road in " reading to cure random notes ": blood still boat also, body fluid water also, water Tianjin is abundant, boat could be gone.

Because the depression qi depression to blood stasis of chronic fatigue syndrome, the pathogenesis of blood stasis due to qi deficiency, thereby influence the absorption distribution, excretory function of human body water and body fluid and cause: phlegm retention syndrome.Song. and Yan Yonghe " Prescriptions for Succouring the Sick. the phlegm retention opinion is controlled " think: people's air flue is expensive suitable, and suitable then free flow of body fluid does not certainly have the trouble of phlegm retention, and it is inappropriate to take good care of oneself, the air flue obturation, water liquid stops diaphragm and forms expectorant.Zhang Zihe " Confucian's Duties to Their Parents. drink aggravates opinion when the temperature compensation of anhydrating " think the origin cause of formation of drink disease have five substantially: have anger strongly fragrant and the person, tired person is arranged, have ponder over and the person, have drink to one's heart content and the person, have hinder when hot cold and the person, though fluid-retention syndrome is many, nothing is for this.

Drink is long-pending can give birth to expectorant, phlegm and blood stasis, and the card feelings are more touching.Phlegm retention stops amassing, and influences ascending or descending movement of vital Qi, but strongly fragrant heat-transformation again for a long time.Gas enclosure stagnates so primary disease has, the difference of folder heat.Phlegm retention is the marquis of overabundant YIN leading to insufficient YANG, deficiency in origin and excess in superficiality in a word, and treatment is a rule of treatment with " warm medicine and it "; Basic to hold up spleen to reinforce the kidney to control.Clearly. and Li Yongcui " card is controlled and converge to be mended. fluid-retention syndrome " point out the treatment order of primary disease: and just should distinguish, inferior should taking good care of, void is invigorating middle warmer then, for a long time suitable warming the kidney.Zhang Zhongjing: " sick phlegm retention person, when with warm medicine and it ".Ye Tianshi: outer drink is controlled spleen, and interior drink is controlled kidney; Zhang Lu " Zhang Shi doctor is logical. phlegm retention ": " phlegm retention becomes and gives birth to all cards generally, and improper holding up for all cards made name, and is elder generation to control drink, drinks all card spontaneous recovery that disappears.”

Depression is except that Drug therapy, spiritual healing is very important, remove pathogenesis, make patient correctly be familiar with and treat the disease of oneself, strengthen the confidence of cure diseases, can promote the improvement and the recovery from illness of depression, say: " melancholia is entirely in patient's easy property of shifting one's love " as " Linzheng Zhinan Yi, melancholia ".Depressed and neural mental symptom Chinese traditional treatment principle is as follows:

" card is controlled to converge and is mended. strongly fragrant disease ": " though strongly fragrant disease is many, all do not circulate because of gas, it is earlier that method is worked as pleasant, and dispersing and elevation is inferior.As for lowering fire and resolving phlegm, removing food stagnancy, still when dividing how much control it ".

Ji Chuchong day: " turbid QI failing to descend also for so-called strongly fragrant person, clear QI failing to ascend.Right pure and impure lifting all goes out lung qi, makes lunar mistake control the order of joint, not only anger do not rise, and getter does not also fall, disharmony of QI of the upper and the lower and strongly fragrant one-tenth.The cloth of right lung qi, the heart is defeated by gastric qi, the fortune of gastric qi, change that must these three warmers; Gastric qi is not declared, due to three warmers are neglected one's duty.

The depression clinical research confirmation: drug for invigorating blood circulation and eliminating stasis can promote organism metabolism, improves the cerebral cortex irritability, cooperates the resolving depression medicine of regulating the flow of vital energy, and can improve depressive state, and prescription is as adding the flavor TAOHONG SIWU TANG.

The cause of disease, the pathogenesis formulation traditional Chinese medical science rule of treatment according to above argumentation and depression are as follows: in the sweet temperature compensation, supplementing QI for promoting the production of body fluid holds up spleen to reinforce the kidney, with the machine lifting of regulating the flow of vital energy; Warming the liver sun, the liver benefiting gas, nourishing the liver blood is changed phlegm and blood stasis, declares the network of promoting blood circulation to treat chronic fatigue syndrome depression and neural mental symptom with the dissipating depression of QI eliminating stagnation.

4. the practical basis that provides of modern medicine study

Chronic fatigue syndrome is to be developed into due to the serious stage by multiple chronic kidney disease.Find from the clinical observation angle: the pathological change of deficiency syndrome; be lowly or too to suppress with function of nervous system; parasympathetic nervous tensity abnormal ascending (non-protection period); myocardial function is reduced; inadequate circulatory blood volume; so that the blood vessel amplitude is dwindled, and basal metabolism decline, and living matter basis deficiency is a feature.Find from the pathological anatomy angle: the dysfunction of a plurality of endocrine body of gland is important step in the pathogenesis its pathogenic process.Find from the immunology angle: the positive weakness of QI of deficiency syndrome patient, consumption of vital essence; Excess syndrome person, though evil the Sheng, healthy energy does not decline, vital essence is not taken by force.Lung is defended insufficiency of function, and lung is defended when being obstructed, and immunologic function all reduces.(kidney-nourishing tcm drug can reach the purpose of enhancing human body immunity function) found from the visceral organ injury aspect: " spleen " of Chinese medicine is a functional unit of many organs, multisystem, and " insufficiency of the spleen " then is that the hypofunction with a plurality of organs, a plurality of systems is a feature.

" insufficiency of the spleen ": patient not only has the reduction of stomach tension force, gastric mucosa to increase thick and the gastric acid high score is secreted tendency, the variation of gastrointestinal tract aspects such as the small intestinal absorption function goes down, colon movement hyperfunctioning; And the vegetative nerve function aspect, it is high partially to show as parasympathetic nervous.Sympathetic tone reduces, thermotaxic centre and vasomotor center imbalance; The E﹠M aspect shows as hypothyroidism, water liquid excretory function obstacle; Immunologic function aspect: the tendency of visible cell immunologic hypofunction.The wriggling function of " deficiency of spleen-YANG " patient stomach descends, and emptying time prolongs and the gastroptosis person sees more.

5. chronic fatigue syndrome pathogenesis research

The different causes of disease acts on different body constitution and forms chronic fatigue syndrome, its pathogenesis character and change of disease trend, though it is complicated unusually, various, but sum up its pathogenesis and change the not outer deficiency of YIN, yang deficiency, the deficiency of vital energy, blood deficiency four ends, and yang-energy, cloudy blood always are the active product of function, thus the loss of yang blood and qi, again often by due to the five internal organs damage." Huatuo's Zhongzang classic " cloud: though illustrate that asthenia can arise from one dirty, the substantial connection owing to existing interpromotion and interrestraint between internal organs interacts " labor arises from one, is together two, two to pass three; threeway is in four; four do in five, five and violate one, one again as for five; heresy is dark Tibetan; vital qi is from losing ", event is the void thanks to of several internal organs of simultaneous, negative and positive, QI and blood often, and this is chronic fatigue syndrome pathogenesis evolution characteristics place.In the pathological process of chronic fatigue syndrome, spleen, kidney, the deficient of liver are the leading links that pathogenesis develops.

6. chronic fatigue syndrome Chinese traditional treatment principle research

According to the traditional Chinese medical science: the diseases caused by exogenous pathogenic factor six climate exopathogens, internal damage by the excessive seven emotions, it is appropriate to the occasion to have some setbacks, do not know to take good care of, long-pending empty one-tenth decreases, and is all the cause that consumption is hindered vital essence, want " diet has joint, and daily life often has, and does not forget to do labor ", grasp: " abnormally climatic pathogens; keep away sometimes, quiet nihility, vital QI in the body flowing normally; keeping a sound mind, sick peace is always " reach " taking food as usual is smart gives birth to " anti-deficient health-preserving method and chronic fatigue syndrome etiology and pathogenesis formulation Therapeutic Principle as follows:

" deficiency syndrome should be treated by tonifying method " (and " element is asked. three ones nine marquis's opinions ") " diseases caused by over-strain should be treated by warming " (" element is asked. the most pure virginity will be discussed greatly ") " decreasing its lung person, its gas of benefit "; Decrease its heart person, transfer its battalion to defend; Decrease its spleen person, transfer its diet, harmonizing the cool with warmth of the body; Decrease its liver person, delay wherein; Decrease its kidney person, its essence of benefit " (" difficult warp. 14 difficulties ") " QI and blood of effecting a permanent cure of the day after tomorrow, congenital method of treatment negative and positive " (" Yizong Jinjian. miscellaneous diseases heart method knack ") and regulating the flow of QI to alleviate depression, the method for phlegm reduction of blood circulation promoting; (" scholar's Lee material cloud: the disease of impairment caused by overstrain, the person that do not have or not the blood stasis is also "); (expectorant be disease, change numerous " disease is controlled because of arteries and veins. phlegm syndrome opinion "); (though strongly fragrant disease is many, all must not circulate because of gas, and it is earlier that method is worked as pleasant, and dispersing and elevation is inferior).

According to above argumentation, determine that chronic fatigue syndrome Chinese traditional treatment rule is: in the sweet temperature compensation, supplementing QI for promoting the production of body fluid holds up spleen to reinforce the kidney, the stasis of blood of reducing phlegm, clearing away damp-heat.

The technical solution used in the present invention is as follows:

A kind of herbal mixture granule for the treatment of chronic fatigue syndrome is the preparations for oral administration that according to dosage is mixed with by plurality of Chinese, and its medicine forms and component content (unit: restrain) is as follows:

Radix Ginseng Rubra (practise and claim Park Ginseng) ₁₀Radix Glehniae ₂₀The Radix Astragali ₁₅Radix Astragali Preparata ₁₅Radix Glycyrrhizae ₅Radix Glycyrrhizae Preparata ₅Rhizoma Polygonati ₁₅Rhizoma Atractylodis Macrocephalae (parched) ₁₀Radix Angelicae Sinensis ₁₀Cortex Magnoliae Officinalis ₁₀Radix Polygoni Multiflori Preparata ₁₀Rhizoma Polygonati Odorati ₁₀

Rhizoma Cimicifugae ₃Radix Bupleuri ₃Folium Nelumbinis ₆Flos Magnoliae ₃Radix Puerariae ₆Radix Saposhnikoviae ₃Herba Schizonepetae ₃Rhizoma Et Radix Notopterygii ₃Radix Angelicae Pubescentis ₃Rhizoma Atractylodis ₁₀Cortex Phellodendri ₃Herba Artemisiae Scopariae ₃Cornu Cervi ₃Carapax Et Plastrum Testudinis ₁₀Rhizoma Cibotii ₃Rhizoma Drynariae ₆Radix Achyranthis Bidentatae ₆The Cortex Eucommiae ₆Radix Dipsaci ₆Cortex Moutan ₁₀

Poria ₁₀Radix Ophiopogonis ₆Rhizoma Zingiberis ₃Pericarpium Citri Reticulatae ₆Rhizoma Pinelliae Preparatum ₃The Radix Aucklandiae ₆Fructus Amomi ₆Radix Paeoniae Alba (parched) ₁₀Fructus Lycii ₆Cortex Lycii ₁₀Rhizoma Cyperi ₁₀Bulbus Fritillariae Cirrhosae ₃Cortex Albiziae ₁₀Fructus Trichosanthis ₆Rhizoma Alismatis ₆Fructus Gardeniae Preparatus ₃Rhizoma Chuanxiong ₃Radix Polygalae ₁₀Flos Lonicerae ₁₅Cortex Cinnamomi ₃(full side is made up of 52 flavor Chinese medicines)

The herbal mixture process for producing granula:

Compound Chinese medicinal preparation of the present invention is a granule, takes by weighing Chinese crude drug (clean medicine) with 52 flavor Chinese medicines by the name of an article and weight ratio, is ground into fine powder, sieves, and fully mixing is made granular formulations and got final product.Granule should meet following pertinent regulations at production and duration of storage:

Can add suitable adjuvant, correctives and aromatic when 1, preparing granule.

2, make fine powder, add an amount of adjuvant, mixing is made granule, drying, and supplementary product consumption be should give control, 5 times of not super clear paste amount.

3, granule should be dry, uniform particles, the color and luster unanimity, the no moisture absorption, soften, phenomenons such as caking, deliquescence.

4, granule should seal storage.

[granularity]: get granule one bag, claim decide weight, put in the medicine sieve and sieve, when sieving, will sieve and keep level, about come and go 3 minutes, can not by sieve with can must not be above 8% by the granule and the powder summation of sieving for No. four.

[moisture]: measure according to aquametry (appendix LXH).

[melting]: get test sample 10 grams, add 20 times of hot water, stirred 5 minutes, observe soluble granule immediately and answer off-bottom, allow slight muddiness.

[device difference]: 6 grams are with ± 5%

[inspection technique]: should meet (appendix XIITC) and check

[microbial limit]: should meet (appendix XIIIC) and check

[specification] every packed 6g-12g

[usage and dosage] is oral, warm boiled water, the 6g-12g that is grown up a time, 3-4 time on the one

[storage] is airtight, protection against the tide

The Chinese traditional compound medicine effect:

In the sweet temperature compensation, supplementing QI for promoting the production of body fluid holds up spleen to reinforce the kidney, the stasis of blood of reducing phlegm, clearing away damp-heat.

The Chinese traditional compound medicine attending scope:

Chronic fatigue syndrome also claims confirmed fatigue, subhealth state, Ya Pishi influenza and immunologic dysfunction syndrome.

The disease performance is as follows:

Inexplicable lasting or in-and-out serious fatigue, and be not that motion causes, can not alleviate by lying up, and cause the obvious decline of work, study and social activity ability and competitiveness; Simultaneously with slight fever; The lymphadenectasis of having sore throat; Muscular tension is low, and muscular flaccidity is ached and be unable; Arthralgia; Headache; Parahypnosis.As drowsiness or insomnia; Dizzy, nauseating; Diarrhea and constipation are alternately; Spirit depressing; Weight increase or alleviate obviously; Night sweat; Anorexia nervosa; Heart beating is overrun; Arrhythmia; Premature beat; Deficiency of QI with disinclination to talk, apathetic expression, absent minded, disturbance in thinking, hypomnesis.Neural mental symptom and immune system abnormality etc.

Chinese traditional compound medicine side separates:

Monarch (master) medicine: the sun of Radix Ginseng Rubra tonifying five ZANG-organs, the moon of Radix Glehniae tonifying five ZANG-organs is given birth to, all void of Radix Astragali Preparata tonifying five ZANG-organs, and Radix Glycyrrhizae (give birth to, process) sugariness is gone into spleen, returns it to like, the machine lifting of regulating the flow of vital energy, coordinating the actions of various ingredients in a prescription and detoxifying.Rhizoma Polygonati is for mending the victory product in yellow palace.The mother of soil person's all things on earth, female that it is supported, then extreme misery promptly helps, and wooden gold is joined, and all heresies are gone certainly, and all kinds of diseases and ailments are not given birth to, Rhizoma Atractylodis Macrocephalae (parched) and middle QI invigorating, and dehumidifying is quenched the thirst, and is antiabortive.Damp must be gone, and is so incensed that circumfluence and Tianjin life.Chinese angelica blood supplementing and blood are controlled all sick nights very.The big tonifying the spleen and stomach of Cortex Magnoliae Officinalis is deficient, warming middle-JIAO to send down the adverse-rising QI, and the card of cold drink, vomiting, diarrhea is removed in the feed of reducing phlegm.Taste gas is strong, then can diet, and diet promptly advances, and then benefit battalion defends, and supports essence and blood, grows bone marrow.(" element is asked " " insufficiency of essence person tonifying with drugs of thick flavor, weakened configuration person benefit with gas ") Radix Polygoni Multiflori Preparata is controlled all chronic diseases of alvus.Invigorate blood circulation and control wind, tonification is arranged greatly, can make QI and blood Taihe county, all diseases are gone.Rhizoma Polygonati Odorati removes headache of Xu Lao Malaria malaria cold and heat and wind heat noxious dampness.

Minister (assisting) medicine: Rhizoma Cimicifugae: the non-Rhizoma Cimicifugae of tonifying the spleen and stomach medicine is quoted and can not be got effect; The non-Rhizoma Cimicifugae of the dysfunction of the spleen can not remove; Disperse positive bright ailment said due to cold or exposure, rise clearing heat in QI system in the stomach, draw sweet using warming therapy medicine again and rise, real its table with loosing of QI invigorating.So the insufficiency of primordial QI person with yang invigorating in this moon, delays the urgency that contracts of dai channel again.Radix Bupleuri draws few positive clearing heat in QI system and rises, and it is up that Rhizoma Cimicifugae draws positive bright clearing heat in QI system.Radix Bupleuri can go internal organs inside and outside all weary, and it is up and along Yang Dao, go into the few sun of foot again to draw clearing heat in QI system.Through main gas, at dirty main blood.The 12 menses stagnation of QI that can loose are poly-, all malarias be monarch,, help and control it through branch with send out place with the medicine of tying-in, simultaneously, Radix Bupleuri is controlled the heat of skin, internal organs, bone marrow.Folium Nelumbinis rises the gas of sending out the few positive first gallbladder of foot, with the few positive three warmers vigour of hands, is all the gas of hair growth promoting, is the root base of a fruit of biochemical all things on earth.The Folium Nelumbinis and the Rhizoma Atractylodis Macrocephalae pull together to nourish, and mend and make the thick unlikely internal injury of stomach.Flos Magnoliae nose gas leads in the sky.It person's head also, lung also, lung opening at nose, and positive bright the stomach pulse ring nose and up, the brain being the house of mentality, and nose is the gate of vitality's a key, QI-insufficiency among the people, clear YANG failing to ascend, then head inclines for it, nine orifices is unfavorable for it.The suffering temperature of Flos Magnoliae is flat and go into lung, and its body is frivolous, and can help on the clear sun of stomach and work in the sky, so, can warming middle-JIAO, control the disease of women's head-ornaments order nose nine orifices.The sweet cold of Radix Puerariae natural disposition, the table that can loose is real, and association's Rhizoma Cimicifugae to be to rise, and makes then clearly that sun reaches, and turbid yin is fallen as can be known.Non-this of Radix Saposhnikoviae tonifying the spleen and stomach is quoted unable to walk.Radix Saposhnikoviae is controlled all over the body to the greatest extent pain, be in the wind medicine the profit agent also.All rachiagia stiffness of the nape can not be looked back, and the severe lumbago as if the lumbar vertebra would break off, like dialling the person is brothers' sun disease, properly use Radix Saposhnikoviae, all skin ulcers more than septum pectorale, energy eliminating stagnation and the top wind of dispelling, patient body is arrested tired person, wind is also.All skin ulcers see that this card also must use it.Radix Saposhnikoviae is separated all poison of drug, and it is bigger that the Radix Astragali gets its merit of Radix Saposhnikoviae.Hot and the temperature of Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis two bitter in the mouth, the thin person of flavor, the yang aspect of yin so can bleed rise, is led to all over the body.And the wind prevailing over dampness that looses, the same usefulness of Rhizoma Et Radix Notopterygii and Rhizoma Chuanxiong is controlled the sun, SHAO YIN headache, closes sharp joint thoroughly, controls governor vessel for sick, back rigidity and faint (product of invigorating middle warmer, the product that must deliver and in from pacifying).Narrow narrow person must use it in the Rhizoma Atractylodis abdomen.Sweet and hot strong, warm in nature and dry, cloudy middle-jiao yang, function of the spleen and stomach also can rise and can fall, and goes into too bright, the hands of the yin, yang warp of bright, the sun of yin, yang too of foot.Diffusing wind QI invigorating is always separated Zhu Yu, control the damp-phlegm prolonged fluid-retention or hold blood stasis under the arm to become the nest capsule, and the wet dirty upper, middle and lower of spleen all has available.Can always separate Zhu Yu again, expectorant, fire, wet, food, gas, blood six kinds of stagnation-syndromes, all not normal because of the development of evil in febrile disease, must not lifting, the disease in middle-JIAO, lifting so medicine must be held concurrently.Desire is risen it, must fall it earlier, will desire to fall it, must rise it earlier.So Rhizoma Atractylodis are sufficient Yangming Channel medicine, the abnormal smells from the patient suffering is strong, and the strong spleen of stomach strengthening is sent out Gu Zhiqi, can directly go into all warps, and the catharsis sun is bright wet, and passing through, it is puckery to hold back.Spleen channel be can't help, and it is more than that urine is leaked turbid pouring, and the back ache should be with Rhizoma Atractylodis to hold back the spleen essence, and so essence is born in paddy also, and Rhizoma Cyperi is the medicine of fast gas in the moon, therapeutic method to keep the adverse QI flowing downwards steepest.So one rise and one drop is strongly fragrant loose and putting down.The Herba Artemisiae Scopariae germinating and sprouting causes newly, the panacea of damp-heat in the spleen and stomach.Treat headache, separate the typhoid fever diaphoresis, the row podomere gas that stagnates, reduce phlegm sharp every, control overstrain and want most.The yang-energy that Cornu Cervi gets the world is the most complete, and kind dredging DU Meridian arteries and veins, foot be in smart person, thus can be how excessive and the longevity, with this thing benefit gate of vitality, the kidney invigorating essence, invigorating primordial QI, all to establish the yang function also; It is the thickest that Carapax Et Plastrum Testudinis gets the cloudy gas in the world, and kind logical conception vessel is sufficient in the gas person, the longevity so lie prostrate breath.With this thing reinforcing the heart, the kidney invigorating, enrich blood all also with yin nourishing.Rhizoma Drynariae, the Cortex Eucommiae, Radix Dipsaci, Cortex Cinnamomi, Rhizoma Cibotii are to help Cornu Cervi the kidney warming sun, and with the dredging DU Meridian arteries and veins, Radix Achyranthis Bidentatae, Cortex Phellodendri are led to conception vessel to help the Carapax Et Plastrum Testudinis nourishing kidney-yin.Cortex Moutan is to let out fire (the congenital QI and blood of effecting a permanent cure, the method for treatment negative and positive of the day after tomorrow) mutually.

Adjuvant drug: Poria draws Radix Ginseng Rubra, mends the vigour of the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels, rushes down the pathogenic fire in the kidney, and the ginseng of helping others Radix Ophiopogonis is to give birth to arteries and veins, and Rhizoma Zingiberis helps the Radix Ginseng Rubra QI invigorating.Pericarpium Citri Reticulatae is in order to the contrary gas of lung gold, and Rhizoma Pinelliae Preparatum is letting out the dampness of spleen soil, and phlegm retention can be removed also.Add the Radix Aucklandiae to go the gas that stagnates of three warmers.Fructus Amomi is with the vigour of logical spleen kidney, and melancholia can be opened also, simultaneously with loose stagnating of all sweet medicines and the turbid descending the moon (agent of QI invigorating, rely the product of clearing heat in QI system and the gas benefit doubly).Radix Paeoniae Alba (parched) acid is received, in order to and flourish, with association Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Saposhnikoviae, Radix Bupleuri, Flos Magnoliae, the hot property of loosing of Rhizoma Cimicifugae.The lid ancients loose with hot, must receive with acid, and institute is in case its high going through, and still military strategist in ancient China's restraining also.Lead the way and can not solely set its merit in ginseng stilbene non-osmanthus, osmanthus must not Radix Glycyrrhizae peace QI and blood, also can not its orderliness of thread, and blood can be controlled in meaning osmanthus, and to promote its poison, the invigorating YANG QI invigorating reaches the whole body to fill.Blood is interior, and that draws goes out table, and then gas is from expelling the toxic substance from the body with tonic, and blood looses outward, and that draws returns root, then gas from outside protect.Rhizoma Zingiberis is with the poison of Rhizoma Pinelliae Preparata, Cortex Magnoliae Officinalis, Rhizoma Polygonati, Fructus Lycii, Cortex Lycii benefit vital essence, reducing the asthenic fever.Always separate Zhu Yu: Rhizoma Atractylodis, Rhizoma Cyperi, Rhizoma Chuanxiong; Internal injury caused by excess of seven emotions is paid no attention to cold and heat and asthenia and sthenia and all can be controlled it: Radix Polygalae.Reason seven emotions QI rising in reverse order: Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, Poria.Pressing down knot does not loose: Carapax Et Plastrum Testudinis, Rhizoma Cyperi.The anger impairing the liver, or strongly fragrant in the melancholy gas, or wind-engaging forms: Herba Schizonepetae.Melancholy is not stretched: Bulbus Fritillariae Cirrhosae.Make us happy carefree: Cortex Albiziae.Fructus Trichosanthis: soothing liver-QI is strongly fragrant, and the profit liver is dry, and suppressing the hyperactive liver is contrary, and slow liver is anxious, function solely arrogate to oneself also.The same tonic of Rhizoma Alismatis can be by the evil dirt of damp-heat in lower-JIAO, and pathogen is promptly gone, and cloudy strong sea is clean.Burnt Fructus Gardeniae is little dry to separate Rhizoma Atractylodis.

Messenger drug: the hot temperature of Rhizoma Chuanxiong, nontoxic.The up head, the descending sea of blood is so clear god and SIWU TANG are all used it.The wind of diffusing Liver Channel is controlled few positive JUE YIN meridian headache, and the panacea of headache due to deficiency of blood.It is with having four: with few positive tying-in; The Zhu Jing headache; Help the gas of sun clearly; Dry gas at head.Strongly fragrant middle Jiao, its gas of palpus Rhizoma Chuanxiong dispersing and elevation is to rise it, and gas lift is then strongly fragrant to fall certainly, so Rhizoma Chuanxiong is always separated Zhu Yu, through three warmers are making of logical yang blood and qi, and adding rhizome of chuanxiong in the medicine is to help, gas promoting the circulation of blood accent, and it is sick only upright, Radix Polygalae: the strong will of energy Fructus Alpiniae Oxyphyllae of these careless clothes, so the title of Radix Polygalae is arranged.All tonics assistant is gone into the heart earlier with tranquilizing the mind with the hardship temperature of Radix Polygalae, makes sweet using warming therapy product, begin redization and be blood, to give living body.Radix Polygalae is gone into kidney meridian, and its merit is specially smart in strong will benefit, controls forgetful.Radix Polygalae wine is controlled all carbuncle outstanding service, covers the Li Er of also the kidney invigorating, if strongly fragrant in the seven emotions, pays no attention to the deficiency and excess cold and heat, and that controls all heals.We are being in harmonious proportion the spleen kidney with the magical effect of Radix Polygalae.The sweet cold of Flos Lonicerae, the Tuoli that relieves internal heat, loose gas and blood, tonify deficiency is treated wind, and it is key medicine that the diffusing poison of detumescence is controlled skin ulcer, and its merit solely wins.Pyretic toxicity migration skin pierces internal organs, every twinge, and change is variable, and attached bone incarnation is attacked the cutter blood vessels, the place of pain is not known at excessive four ends that jump, and every in a trance, and the entanglement internal organs dash and draw the heart side of body, and every strand is cut, meet cold and just do, it is heavy to lift body, and spirit is mixed, and common dusk is useless, and every solar term are your writing extremely then.More than all cards and be that the poison of interior-heat draws and connects exopathogen and all can use Flos Lonicerae and control it.Cortex Cinnamomi Gan Xinre returns Liver and kidney two warps, keeps and does not walk, and goes into blood system, can guiding fire to origin.Simultaneously Cortex Cinnamomi can warm flourish nutrient blood, and help the effect of QI and blood growth.Blood can be controlled in meaning osmanthus, and to promote its poison, the invigorating YANG QI invigorating reaches the whole body to fill.Blood is interior, and that draws goes out to show, and then gas is from expelling the toxic substance from the body with tonic; Blood looses outward, and that draws returns root, then gas from outside protect.Leading the way in ginseng stilbene non-osmanthus, can not solely set its merit, and osmanthus must not Radix Glycyrrhizae peace QI and blood, also can not its orderliness of thread.To be that engaging earlier of all medicines is logical make Shennong's Herbal meaning Cortex Cinnamomi, the gas that lid is scurried because of its perfume (or spice), and interior and internal organs muscles and bones, outer and meridians space between skin and muscles, all medicines part of can not leading to has Cortex Cinnamomi to draw it, then there's no one who doesn't or isn't reaches also (drawing the through sick institute of all medicine persons) thoroughly.

Compatibility of drugs basis and treatment be principle (side's card is analyzed) more:

The lid people is this with the gastric qi all over the body.Gastric qi is prosperous, and then the five internal organs are subjected to shade; Damaged stomach-QI then all kinds of diseases and ailments from life.So all diseases do not heal for a long time, all medicines are effect person not, only stomach reinforcing, the kidney invigorating two ways.So we with decoction of four noble drugs with card plus-minus, no matter cold and heat reinforcing and reducing, soil in the training earlier, messenger drug gas four reaches, then the machine convection on the whole body leads to, the little compress of foodstuff essence, what suffers from its medicine does not imitate! It is auxilliary that four monarchs get (Pericarpium Citri Reticulatae, the Rhizoma Pinelliae, the Radix Aucklandiae, Fructus Amomi) four, the unlikely mud of tonic and not all right then, and four auxilliary four monarchs, and benefit power is doubly declared, four auxilliaryly have four monarchs and vigour is good, mutual reinforcement between and the clear person of benefit!

Soup (Radix Ginseng Rubra, the Radix Astragali, Radix Angelicae Sinensis, Rhizoma Chuanxiong, Radix Rehmanniae Preparata, the Radix Paeoniae Alba) is healed to control diseases such as the deficiency of YIN, blood prostration with the sage in the side.Tangible blood can not speed be given birth to, and invisible gas is worked as anxious solid; See that blood do not control blood, must transfer its gas earlier; Four things must not Qi-tonifying drug, can not become the merit of Yin grows while yang is generating.(deficiency of YIN does not have the method for rapid benefit, and meter is being deposited sun; Blood prostration has the machine of hemopoietic, must first QI invigorating.This Yin grows while yang is generating, blood are with the capable reason of gas also) this Six-element medicine obeys it, and mellow peace and moistening makes QI and blood mediation, interior external harmonics.

It is three strange that the people has.Essence, gas, god give birth to root of life also.

The smart wound is difficult anger, and impairment of QI is difficult to give birth to refreshing, insufficiency of essence person tonifying with drugs of thick flavor.

The side uses: Testudinis deer semifluid extract of ginseng and antler glue (Li Shicai) is mended marrow greatly, and QI invigorating is reposed.The genus of Cornu Cervi, Carapax Et Plastrum Testudinis two thing QI and blood, good fortune is profound little again, and the foreign peoples is in love, and the method for the broken bamboo benefit of bamboo is also.Radix Ginseng Rubra is timid in the positive QI invigorating; Fructus Lycii is cloudy, the fire among the clear god.Monoyin and monoyang does not have the melancholy of Sheng partially; Go into gas and go into blood, have and close flat U.S..Smart giving birth to and gas is prosperous, gas is prosperous then refreshing prosperous.Governor vessel is a sun, and conception vessel be cloudy, positively rise the moon and fall, health always.

All taste:

Happiness: sweet, mend, temperature, logical, liter, dry.

Dislike: bitter, attack, tremble with fear, stagnate, fall, wet.

On the whole after the man-year 50, the person of disappearing is many for its gas, and the elder is many; The person of falling is many, and the person of liter is few, and the order of autumn and winter is many, and making of spring and summer is few." element is asked " cloud: " cloudy smart institute gives its life insurance, and the smart institute of sun falls its people and dies young." " interior warp " in the system person not of pin, medicine institute, transfer with sweet medicine.Among the lid sugariness master, lifting is arranged, up and down, can be outward can in, have and have slow, have to mend and let out, road placed in the middle is to the greatest extent.The day after tomorrow spleen soil, gas that must be congenital is not all right.

This gas is because of the labor kidney liver of sinking, clear YANG failing to ascend, turbid YIN failing to descend.

Draw more than the gastric qi and rise, multiple its one's own department or unit enables to rise floating order with the row growth." interior warp " cloud: " with sweet benefit it, let out it with sweet, with sweet slow it ".The agent of all YANG invigorating can rise, and just rises also with the sun master.Cloud again: " person of exhausting under the negative and positive can not rise.(kidney) "

From BUZHONG YIQI TANG, raising splenoyang to strengthen stomach soup, SHENGMA GEGEN TANG, Pingwei San draws inspiration in the XIAOYAO POWDER:

The side uses: Radix Ginseng Rubra, the Radix Astragali, Radix Glycyrrhizae, Radix Glycyrrhizae Preparata, the Rhizoma Atractylodis Macrocephalae, Radix Angelicae Sinensis, Cortex Magnoliae Officinalis, Rhizoma Atractylodis, Pericarpium Citri Reticulatae, Rhizoma Cimicifugae, Radix Bupleuri, Radix Angelicae Pubescentis, Rhizoma Et Radix Notopterygii, Radix Puerariae, Radix Saposhnikoviae, Poria, Rhizoma Alismatis, Rhizoma Pinelliae Preparatum, Cortex Moutan, Fructus Gardeniae, Radix Paeoniae Alba (parched), Radix Glycyrrhizae.

Add: Radix Adenophorae (Radix Glehniae), Rhizoma Polygonati, Rhizoma Polygonati Odorati, Radix Polygoni Multiflori, Folium Nelumbinis, Flos Magnoliae, Herba Schizonepetae, Cortex Phellodendri, Herba Artemisiae Scopariae.

With the deficiency of YIN, YANG and QI tonifying blood, the loss of the beneficial heart, liver, spleen, lung, kidney, the machine lifting of regulating the flow of vital energy.

The side uses: YUPINGFENG SAN (Radix Saposhnikoviae, the Radix Astragali, the Rhizoma Atractylodis Macrocephalae) is controlled that exopathogen is stayed for a long time and is not loose the person.

The institute of heresy gathers, and its gas must be empty.So the person that controls wind, do not have to suffer from and be difficult to drive it, be difficult to drive it and suffer from, not going of anemophobia not, and the multiple of anemophobia comes.He Ze? disperse too, so Xuan Fu does not close yet.Ignorant person does not know the method for Tuoli consolidating superficial resistance, and driving it, the person of going is from going all over examination wind medicine, the person that has come from the beginning, pathogen is lingered on, and does not have eventually and separates the phase.

Radix Saposhnikoviae claims to control the elixir of wind all over going the whole body, last refresh oneself's seven apertures, and the interior joint paralysis of removing is separated the extremity contraction outward suddenly, is the profit agent of wind medicine, controls wind and solely gets this flavor, and the accepting a heavy burden merit is special.The person that so defends gas, thus warm boundary between muscles and fill skin, fertile space between skin and muscles and take charge of out entirely, only the Radix Astragali can be mended; Three warmers and real defending is the key that Xuan Fu drives wind, and have antiperspirant can send out, lossless energy ends, the same Ramulus Cinnamomi of merit, thus can remove head's wind heat again, strong wind leprosy disease, discharging fresh blood stool, the sub dirty wind of married woman, be the tonic apoplectic also, so Radix Saposhnikoviae gets the Radix Astragali, its merit heals greatly.Rhizoma Atractylodis Macrocephalae strengthening the spleen and stomach, warm boundary between muscles, ridging Ning Fengye.The husband gets the Radix Astragali with consolidating superficial resistance with the kind wind dispelling of Radix Saposhnikoviae, then defends to some extent outward; The Rhizoma Atractylodis Macrocephalae with in solid, then in certificate to some extent, and ailment said due to cold or exposure goes not come again.

Liver is bitter anxious, anxious food sweet flavor has the effect of relaxing.The lid liver is impatient, susceptible to get angry, and its gas is up then suitable, and is descending then strongly fragrant, and Yu Zehuo is moving, and all diease occurrences.And the strongly fragrant person of edema with the liver involved, its said two: one for native void can not litre also; One for insufficiency of blood can not nourishing the liver also.The lid liver is a wood gas, and the full soil that relies is with nourishing, and water is to irrigate, if the middle deficiency of vital energy, then Radix rehmanniae preparata (Radix Rehmanniae preparatum) (temper that refers to dark Tibetans) does not rise, and wood is therefore strongly fragrant, cloudy insufficiency of blood, then wooden anhydrous profit, and liver is then with withered, (people know that Wood restricts earth do not know native litre).

The side uses: the Rhizoma Atractylodis Macrocephalae, Poria person help native moral with litre also; Radix Angelicae Sinensis, Radix Paeoniae person, beneficial flourish blood is with nourishing the liver also; Cortex Moutan analgesic in, grass, the smart fire of Cape jasmine are in down.Solely Radix Bupleuri simply, one makes with the cloudy newspaper of fainting, one with sending up the lucid YANG.Through cloud: wooden Yu Ze soothing the liver, it wants Radix Bupleuri!

Deficiency of YIN person, sun must gather it, so heat.Deficiency of YIN bringing about fever.Yang-energy falls in the moon, must generate heat.YANG pathogen is absorbed in lunar spleen, when invigorating the spleen and replenishing QI with elevate a turnable ladder it, clear sun reset and fire from putting out also; If sink into down cloudy kidney portion, when LIUWEI DIHUANG WAN treating it, strengthening renal yin to inhibit predominant yang and fiery self-balancing are also; The cloudy liver of sinking into to faint, when the Cortex Lycii drink is mended it with cold, blood hide to some extent and fire from peace also.

SIWU TANG is the agent that liver man YIN nourishing is transferred blood, adds fire in the clear will of Cortex Lycii to pacify kidney, mends it not also; Add fire among the clear god of Cortex Moutan with the cool heart, rush down its son also.Two skins are cool and moisten, but clearing away liver-fire not imapirment of the spleen and stomach so XIAOYAO POWDER treating the liver fire strongly fragrant also dirty in this, soothing the stagnant liver, along its property also; What Cortex Lycii drink was controlled YIN pathogen sinks into liver also, diseases with invaded pathogens should be treated by expelling, and vertical bandit is to lose the patient, all man capable agent (treating the liver two methods) of liver of two sides.

Ginseng person ginseng also, with vigour be counsellor person also.Do not hold also usefulness of the deficiency of vital energy, promptly blood deficiency also should be used; The suitable usefulness of internal injury, diseases caused by exogenous pathogenic factor also should be used.Lid is tired to be drunk by pathogenic fire, Radix Ginseng and cloudy Tianjin from long; This gas of swelling is stopped up, Radix Ginseng and painful abdominal mass is vexed disappears entirely.So that food do not desire into, eat anti-expanding, or regurgitation choke every, let out sharp exhaustion of YIN, aversion to cold with a feeling of cold water sprinkling over the body, hyperhidrosis disease such as leak out, do not have good Radix Ginseng energetically, make the hedge of vigour.The injustice of lung gold heat, is not non-ginseng rescued, and is full among insufficiency of the spleen, what strong fortune of non-participation art? so this merit chief group grass also.

The bitter temperature of Cortex Magnoliae Officinalis red complexion can help few fire with anger.Folium Nelumbinis method shake, go into liver man and and the chamber of store blood." the kidney dominating water metabolism, be subjected to the essence of five ZANG-organs and six FU-organs and hide it ", again day: " kidney person master stings, the dominator of storing essence, smart part is also ".The lid kidney is dirty for be short of (shortcoming), and is how empty few real, because of edema with the liver involved is a son, likes the catharsis mother-qi partially, and the fire one of the moon of fainting is moving, and essence is promptly excessive thereupon, and the condition liver is hidden soul again, and the state of mind is not taken the photograph, and the ghost that crouches suitable its night is handed over, and the disease that essence is let out is done.Feng sui micropills is the controlling nocturnal emission with astringent drugs key medicine, with the hard kidney of its bitter cold, the kidney duty gets hard with Cortex Phellodendri in the side, and then unexpected its of YIN edema overflows, cold can be respectful clearly, then imperial fire is unlikely to excite, and combination of essence and spirit is taken the photograph, does essence have uneasy its person? assistant is with Radix Glycyrrhizae, with sweet energy emergency, rush down within all fire and the liver-fire and be tired of, and can make water and soil be combined into a family, with consolidating that wonderful envelope is hidden.If the sand person that contracts is warm in nature with its acrid in the mouth, kindly can go into kidney, evils of kidney be dry, and the person of profit suffering only, and the sand that contracts leads to three warmers, reaches body fluid, can receive the essence of five ZANG-organs and six FU-organs and belongs to kidney, and the gas of kidney man is received, oneself Tibetan of the marrow in the kidney.

Chinese traditional compound medicine curative effect mechanism:

Modern medicine study and long-term clinical treatment practice have confirmed that curative effect mechanism is: the functional activity that improves body internal organs, tissue, organ, enhancing human body immunity power, improve the resistance against diseases of body, keep the balance of body internal and external environment, the recovery of microcirculation improvement, enhancing metabolism, promotion pathological tissues, defying age, resisting fatigue strengthens the living matter basis.

The excellent characteristics introduction of prior art:

This Chinese traditional compound medicine is to research and develop under the instruction of Chinese Medicine theory.The inventor is to the establishment of chronic fatigue syndrome disease, card, the cause of disease, pathogenesis, Therapeutic Method and have on the utilization systematic study basis of efficacious prescriptions medicine, proposition is with in the sweet temperature compensation, supplementing QI for promoting the production of body fluid, hold up spleen to reinforce the kidney, the stasis of blood of reducing phlegm, the clearing away damp-heat method of treatment is treated chronic fatigue syndrome, thereby determined the treatment rule, and with " method " system side, unified and the association of " Fang Yifa goes out " " reason, method, side, medicine, monarch, minister, help, make ", and emphasize dialectical execute to control with debating disease execute to control and combine, promptly meet theory of Chinese medical science, outstanding again Chinese medicine characteristic.

Differential diagnosis of diseases (is used the name of disease of modern medicine: chronic fatigue syndrome) combine with dialectical (Syndrome in TCM name: deficient), improved the accuracy of diagnosis and treatment; Determination of treatment based on pathogenesis obtained through differentiation of symptoms and signs combines with specific prescription and medication, has strengthened the specific aim of medication; The strict chronic fatigue syndrome vital QI being weakened and pathogen being violent of pressing of the composition of prescription of innovation herbal mixture (plan side certainly) and consumption, simulataneous insufficiency and excessive, with void is this, with the domination of pathogen is that target pathogenic characteristic and method of treatment are established, and strict by monarch, minister, help, make medicine combination principle prescription, given prominence to wholistic therapy, the aim of strengthening the body resistance, the high efficiency and the safety that have improved prescription.Preponderating aspect the physiological function of regulating and strengthen internal organs, tissue, organ, defying age, resisting fatigue, the human body immunity improving ability.

Chinese medicine compound multicomponent, many target spots, multipath effect characteristics and a plurality of effective site combine, and promptly meet theory of Chinese medical science, meet the modernization of Chinese medicine again.The Chinese medicinal ingredients complexity is difficult to produce drug resistance, and prescription is established at pathogenesis, belongs to the agent that effects a permanent cure.

The research thinking of innovation, strict compatibility is concocted, and the consumption of making a distinction between the important and the lesser one has been determined the comprehensive and chronicity of medicine for treatment, is applicable to the treatment in each period of different nationalities, age, sex and complication patient thereof.The preparation medicine source is abundant, and preparation technology is simple, and is with low cost, evident in efficacy, and market prospect is wide, has exploitation and is worth.

In the Chinese medicine compound between each single medicinal material, on effect, exist mutually promote, complex relationship such as mutual restriction.They bring out the best in each other, and complement each other, and therapeutic domain are wide, and toxic and side effects is little.Because compound recipe has multifactor, many target spots, dynamic, drug combination, the characteristics of general performance drug effect, so its effect often is the property adjusted, amphicheirality, comprised in the intravital mechanism of people and respectively to have formed between medicine, between each active ingredient, influencing each other, interacting between medicine and body, functional status, between medicine and internal microorganism.

The specific embodiment:

A kind of Chinese traditional compound medicine for the treatment of chronic fatigue syndrome and preparation method thereof, preparation comprise that multiple composition is as follows:

Monarch (master) medicine: Radix Ginseng Rubra (practise and claim Park Ginseng) Radix Glehniae Radix Astragali Radix Astragali Preparata Radix Glycyrrhizae Radix Glycyrrhizae Preparata Rhizoma Polygonati Rhizoma Atractylodis Macrocephalae (parched) Radix Angelicae Sinensis Cortex Magnoliae Officinalis Radix Polygoni Multiflori Preparata Rhizoma Polygonati Odorati

Minister (assisting) medicine: Rhizoma Cimicifugae Radix Bupleuri Folium Nelumbinis Flos Magnoliae Radix Puerariae Radix Saposhnikoviae Herba Schizonepetae Rhizoma Et Radix Notopterygii Radix Angelicae Pubescentis Rhizoma Atractylodis Cortex Phellodendri Herba Artemisiae Scopariae Cornu Cervi Carapax Et Plastrum Testudinis Rhizoma Cibotii Rhizoma Drynariae Radix Achyranthis Bidentatae Cortex Eucommiae Radix Dipsaci Cortex Moutan

Adjuvant drug: Poria Rhizoma Zingiberis Radix Ophiopogonis Pericarpium Citri Reticulatae Rhizoma Pinelliae Preparatum Radix Aucklandiae Fructus Amomi Radix Paeoniae Alba (parched) Fructus Lycii Cortex Lycii Rhizoma Cyperi Bulbus Fritillariae Cirrhosae Cortex Albiziae Fructus Trichosanthis Rhizoma Alismatis Fructus Gardeniae Preparatus

Messenger drug: Rhizoma Chuanxiong Radix Polygalae Flos Lonicerae Cortex Cinnamomi

The concrete consumption of each composition is (a unit: gram) in the preparation

Monarch (master) medicine: Radix Ginseng Rubra (practise and claim Park Ginseng) ₁₀Radix Glehniae ₂₀The Radix Astragali ₁₅Radix Astragali Preparata ₁₅Radix Glycyrrhizae ₅Radix Glycyrrhizae Preparata ₅Rhizoma Polygonati ₁₅Rhizoma Atractylodis Macrocephalae (parched) ₁₀Radix Angelicae Sinensis ₁₀Cortex Magnoliae Officinalis ₁₀Radix Polygoni Multiflori Preparata ₁₀Rhizoma Polygonati Odorati ₁₀

Minister (assisting) medicine: Rhizoma Cimicifugae ₃Radix Bupleuri ₃Folium Nelumbinis ₆Flos Magnoliae ₃Radix Puerariae ₆Radix Saposhnikoviae ₃Herba Schizonepetae ₃Rhizoma Et Radix Notopterygii ₃Radix Angelicae Pubescentis ₃Rhizoma Atractylodis ₁₀Cortex Phellodendri ₃Herba Artemisiae Scopariae ₃Cornu Cervi ₃Carapax Et Plastrum Testudinis ₁₀Rhizoma Cibotii ₃Rhizoma Drynariae ₆Radix Achyranthis Bidentatae ₆The Cortex Eucommiae ₆Radix Dipsaci ₆Cortex Moutan ₁₀

Adjuvant drug: Poria ₁₀Radix Ophiopogonis ₆Rhizoma Zingiberis ₃Pericarpium Citri Reticulatae ₆Rhizoma Pinelliae Preparatum ₃The Radix Aucklandiae ₆Fructus Amomi ₆Radix Paeoniae Alba (parched) ₁₀Fructus Lycii ₆Cortex Lycii ₁₀Rhizoma Cyperi ₁₀Bulbus Fritillariae Cirrhosae ₃Cortex Albiziae ₁₀Fructus Trichosanthis ₆Rhizoma Alismatis ₆Fructus Gardeniae Preparatus ₃(16 flavor)

Messenger drug: Rhizoma Chuanxiong ₃Radix Polygalae ₁₀Flos Lonicerae ₁₅Cortex Cinnamomi ₃

Herbal mixture granule prescription

Radix Ginseng Rubra (practise and claim Park Ginseng) ₁₀Radix Glehniae ₂₀The Radix Astragali ₁₅Radix Astragali Preparata ₁₅Radix Glycyrrhizae ₅Radix Glycyrrhizae Preparata ₅Rhizoma Polygonati ₁₅

Rhizoma Atractylodis Macrocephalae (parched) ₁₀Radix Angelicae Sinensis ₁₀Cortex Magnoliae Officinalis ₁₀Radix Polygoni Multiflori Preparata ₁₀Rhizoma Polygonati Odorati ₁₀Rhizoma Cimicifugae ₃Radix Bupleuri ₃

Folium Nelumbinis ₆Flos Magnoliae ₃Radix Puerariae ₆Radix Saposhnikoviae ₃Herba Schizonepetae ₃Rhizoma Et Radix Notopterygii ₃Radix Angelicae Pubescentis ₃Rhizoma Atractylodis ₁₀Cortex Phellodendri ₃

Herba Artemisiae Scopariae ₃Cornu Cervi ₃Carapax Et Plastrum Testudinis ₁₀Rhizoma Cibotii ₃Rhizoma Drynariae ₆Radix Achyranthis Bidentatae ₆The Cortex Eucommiae ₆Radix Dipsaci ₆

Cortex Moutan ₁₀Poria ₁₀Radix Ophiopogonis ₆Rhizoma Zingiberis ₃Pericarpium Citri Reticulatae ₆Rhizoma Pinelliae Preparatum ₃The Radix Aucklandiae ₆Fructus Amomi ₆

Radix Paeoniae Alba (parched) ₁₀Fructus Lycii ₆Cortex Lycii ₁₀Rhizoma Cyperi ₁₀Bulbus Fritillariae Cirrhosae ₃Cortex Albiziae ₁₀Fructus Trichosanthis ₆

Rhizoma Alismatis ₆Fructus Gardeniae Preparatus ₃Rhizoma Chuanxiong ₃Radix Polygalae ₁₀Flos Lonicerae ₁₅Cortex Cinnamomi ₃

The herbal mixture process for producing granula:

Compound Chinese medicinal preparation of the present invention is a granule, takes by weighing Chinese crude drug (clean medicine) with 52 flavor Chinese medicines by the name of an article and weight ratio, is ground into fine powder, sieves, and fully mixing is made granular formulations and got final product.Granule should meet following pertinent regulations at production and duration of storage:

Can add suitable adjuvant, correctives and aromatic when 1, preparing granule.

2, make fine powder, add an amount of adjuvant, mixing is made granule, drying, and supplementary product consumption be should give control, 5 times of not super clear paste amount.

3, granule should be dry, uniform particles, the color and luster unanimity, the no moisture absorption, soften, phenomenons such as caking, deliquescence.

4, granule should seal storage.

[granularity]: get granule one bag, claim decide weight, put in the medicine sieve and sieve, when sieving, will sieve and keep level, about come and go 3 minutes, can not by sieve with can must not be above 8% by the granule and the powder summation of sieving for No. four.

[moisture]: measure according to aquametry (appendix LXH).

[melting]: get test sample 10 grams, add 20 times of hot water, stirred 5 minutes, observe soluble granule immediately and answer off-bottom, allow slight muddiness.

[device difference]: 6 grams are with ± 5%

[inspection technique]: should meet (appendix XIIIC) and check

[microbial limit]: should meet (appendix XIIIC) and check

[specification] every packed 6g-12g

[usage and dosage] is oral, warm boiled water, the 6g-12g that is grown up a time, 3-4 time on the one

[storage] is airtight, protection against the tide

[function] modern medicine study and long-term clinical treatment practice have confirmed that curative effect mechanism is: the functional activity that improves body internal organs, tissue, organ, enhancing human body immunity power, improve the resistance against diseases of body, keep the balance of body internal and external environment, the recovery of microcirculation improvement, enhancing metabolism, promotion pathological tissues, defying age, resisting fatigue strengthens the living matter basis.

In the sweet temperature compensation, supplementing QI for promoting the production of body fluid, hold up spleen reinforce the kidney, the reduce phlegm stasis of blood, clearing away damp-heat

[attending scope] chronic fatigue syndrome also claims confirmed fatigue, subhealth state, Ya Pishi influenza and immunologic dysfunction syndrome.

[concrete disease performance] inexplicable lasting or in-and-out serious fatigue, and be not that motion causes, can not alleviate by lying up, and cause the obvious decline of work, study and social activity ability and competitiveness; Simultaneously with slight fever; The lymphadenectasis of having sore throat; Muscular tension is low, and muscular flaccidity is ached and be unable; Arthralgia; Headache; Parahypnosis.As drowsiness or insomnia; Dizzy, nauseating; Diarrhea and constipation are alternately; Spirit depressing; Weight increase or alleviate obviously; Night sweat; Anorexia nervosa; Heart beating is overrun; Arrhythmia; Premature beat; Deficiency of QI with disinclination to talk, apathetic expression, absent minded, disturbance in thinking, hypomnesis.Neural mental symptom and immune system abnormality etc.

Claims (1)

1. treat chronic fatigue syndrome disease (names of disease of tcm: herbal mixture granule deficient disease) for one kind, it is the preparations for oral administration that according to dosage is mixed with by plurality of Chinese, it is characterized in that: full side is made up of 52 flavor Chinese medicines, and it respectively forms medicine, and reaching in the gram is that the content of unit is as follows:

Radix Ginseng Rubra (practise and claim Park Ginseng) ₁₀Radix Glehniae ₂₀The Radix Astragali ₁₅Radix Astragali Preparata ₁₅Radix Glycyrrhizae ₅Radix Glycyrrhizae Preparata ₅Rhizoma Polygonati ₁₅Rhizoma Atractylodis Macrocephalae (parched) ₁₀Radix Angelicae Sinensis ₁₀Cortex Magnoliae Officinalis ₁₀Radix Polygoni Multiflori Preparata ₁₀Rhizoma Polygonati Odorati ₁₀

Rhizoma Cimicifugae ₃Radix Bupleuri ₃Folium Nelumbinis ₆Flos Magnoliae ₃Radix Puerariae ₆Radix Saposhnikoviae ₃Herba Schizonepetae ₃Rhizoma Et Radix Notopterygii ₃Radix Angelicae Pubescentis ₃Rhizoma Atractylodis ₁₀Cortex Phellodendri ₃Herba Artemisiae Scopariae ₃Cornu Cervi ₃Carapax Et Plastrum Testudinis ₁₀Rhizoma Cibotii ₃Rhizoma Drynariae ₆Radix Achyranthis Bidentatae ₆The Cortex Eucommiae ₆Radix Dipsaci ₆Cortex Moutan ₁₀

Poria ₁₀Radix Ophiopogonis ₆Rhizoma Zingiberis ₃Pericarpium Citri Reticulatae ₆Rhizoma Pinelliae Preparatum ₃The Radix Aucklandiae ₆Fructus Amomi ₆Radix Paeoniae Alba (parched) ₁₀Fructus Lycii ₆Cortex Lycii ₁₀Rhizoma Cyperi ₁₀Bulbus Fritillariae Cirrhosae ₃Cortex Albiziae ₁₀Fructus Trichosanthis ₆Rhizoma Alismatis ₆Fructus Gardeniae Preparatus ₃Rhizoma Chuanxiong ₃Radix Polygalae ₁₀Flos Lonicerae ₁₅Cortex Cinnamomi ₃