CN1709846A - Method for producing resveratrol extracted from peanut root - Google Patents
Method for producing resveratrol extracted from peanut root Download PDFInfo
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- CN1709846A CN1709846A CN 200510040625 CN200510040625A CN1709846A CN 1709846 A CN1709846 A CN 1709846A CN 200510040625 CN200510040625 CN 200510040625 CN 200510040625 A CN200510040625 A CN 200510040625A CN 1709846 A CN1709846 A CN 1709846A
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- peanut root
- ethanol
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- resveratrol
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Abstract
This invention has disclosed a kind of producing method to extract resveratrol from peanut root, including such steps as raw materials pretreatment, extract with the solvent, high pressure chromatography elution and polishing. This method is simple and extraction convenient, raw materials getting easy, costs little. It is high in purity and its productivity can be more than 0.88 permillage.
Description
Technical field:
The present invention relates to a kind of extracting method of trans-resveratrol.
Background technology:
Trans-resveratrol is to be used to resist a kind of important hexichol alkene stilbene Polyphenols biochemical substances that pathogeny infects in the plant materials, have significantly antibiotic, anti-oxidant, antitumor, antithrombotic, reducing blood-fat, biological activitys such as strengthening immunity, along with world today's field of biological pharmacy scope constantly enlarges, trans-resveratrol also is one of focus of world today's field of biological pharmacy research, external pharmaceutical products and the functional foodstuff of making by trans-resveratrol, new lover on the world market especially, as important pharmaceutical intermediate and functional foodstuff, be widely used in biochemistry, pharmacy and food service industry.Existing trans-resveratrol product major part is produced from the Chinese medicine giant knotweed, and cost is higher, the technology relative complex.
Summary of the invention:
The object of the present invention is to provide a kind of method simple, it is convenient to extract, and raw material is easy to get, the production method of the resveratrol extracted from peanut root that production cost is low.
Technical solution of the present invention is:
A kind of production method of resveratrol extracted from peanut root is characterized in that: adopting the peanut root is that raw material extracts.
The production method of described resveratrol extracted from peanut root is characterized in that: comprise the following steps: successively
1. raw materials pretreatment: dried flower is taken root with the mixed liquid dipping processing of ethanol and sodium hydroxide;
2. use solvent extraction: the peanut root ethanol that will 1. handle through step is that solvent soaks extraction, gets extracting solution;
3. the extracting solution that 2. step is obtained is through high pressure chromatography wash-out, refining trans-resveratrol product.
The consumption of 1. middle ethanol of step and sodium hydroxide mixed solution is 30～50% of a peanut root by weight, and the weight ratio of ethanol and sodium hydroxide is in the mixed solution: ethanol: sodium hydroxide=10: 0.2～1, the time of immersion treatment is 24～72 hours.
The 2. middle ethanol consumption of step is 20～130% of peanut root raw material by weight, and extraction time is 2～6 hours.
With the peanut root that 2. step is handled through extraction using alcohol, add ethyl acetate again and the alcoholic acid mixed solution extracts, the extracting solution merging that 2. extraction liquid that obtains and step obtain enters step and 3. handles.
The consumption of ethyl acetate and alcohol mixeding liquid is 50～100% of peanut root raw material by weight, and ethyl acetate and alcoholic acid weight ratio are ethyl acetate in the mixed solution: ethanol=0.2～0.5: 1, and the extraction time is 2～6 hours.
The inventive method is simple, and it is convenient to extract, and raw material is easy to get, and production cost is low, the product purity height, and the product yield reaches more than 0.88 ‰.
The invention will be further described below in conjunction with embodiment.
A kind of production method of resveratrol extracted from peanut root comprises the following steps: successively
1. raw materials pretreatment: dried flower is taken root with the mixed liquid dipping processing of ethanol and sodium hydroxide, the consumption of ethanol and sodium hydroxide mixed solution is 30～50% (examples 30%, 40%, 50%) of peanut root by weight, the weight ratio of ethanol and sodium hydroxide is in the mixed solution: ethanol: sodium hydroxide=10: 0.2～1 (example 10: 0.2,10: 0.6,10: 1), the time of immersion treatment is 24～72 hours (example 24 hours, 48 hours, 72 hours).
2. use solvent extraction: the peanut root ethanol that will 1. handle through step is that solvent soaks 2～6 hours (example 2 hours, 4 hours, 6 hours) of extraction, get extracting solution, the ethanol consumption is 20～130% (examples 20%, 80%, 130%) of peanut root raw material by weight.The peanut root that to handle through above-mentioned steps again, adding ethyl acetate and alcoholic acid mixed solution extracts, the consumption of ethyl acetate and alcohol mixeding liquid is 50～100% (50%, 75%, 100%) of peanut root raw material by weight, ethyl acetate and alcoholic acid weight ratio are ethyl acetate in the mixed solution: ethanol=0.2～0.5: 1 (example 0.2: 1,0.35: 1,0.5: 1), the extraction time is 2～6 hours (example 2 hours, 4 hours, 6 hours), extraction liquid that obtains and the above-mentioned extracting solution that obtains through extraction using alcohol merge, and enter step and 3. handle.
3. the liquid that 2. step is obtained is behind high pressure chromatography wash-out, through concentrated, the centrifugal high-purity resveratrol product that obtains.
Claims (6)
1, a kind of production method of resveratrol extracted from peanut root is characterized in that: adopting the peanut root is that raw material extracts.
2, the production method of resveratrol extracted from peanut root according to claim 1 is characterized in that: comprise the following steps: successively
1. raw materials pretreatment: dried flower is taken root with the mixed liquid dipping processing of ethanol and sodium hydroxide;
2. use solvent extraction: the peanut root ethanol that will 1. handle through step is that solvent soaks extraction, gets extracting solution;
3. the extracting solution that 2. step is obtained is through high pressure chromatography wash-out, refining trans-resveratrol product.
3, the production method of resveratrol extracted from peanut root according to claim 2, it is characterized in that: the consumption of 1. middle ethanol of step and sodium hydroxide mixed solution is 30～50% of peanut root by weight, the weight ratio of ethanol and sodium hydroxide is in the mixed solution: ethanol: sodium hydroxide=10: 0.2～1, the time of immersion treatment is 24～72 hours.
4, according to the production method of claim 2 or 3 described resveratrol extracted from peanut root, it is characterized in that: the 2. middle ethanol consumption of step is 20～130% of peanut root raw material by weight, and extraction time is 2～6 hours.
5, according to the production method of claim 2 or 3 described resveratrol extracted from peanut root, it is characterized in that: the peanut root that 2. step is handled through extraction using alcohol, add ethyl acetate again and the alcoholic acid mixed solution extracts, the extracting solution that 2. extraction liquid that obtains and step obtain merges, and enters step and 3. handles.
6, the production method of resveratrol extracted from peanut root according to claim 5, it is characterized in that: the consumption of ethyl acetate and alcohol mixeding liquid is 50～100% of peanut root raw material by weight, ethyl acetate and alcoholic acid weight ratio are ethyl acetate in the mixed solution: ethanol=0.2～0.5: 1, and the extraction time is 2～6 hours.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510040625 CN1709846A (en) | 2005-06-17 | 2005-06-17 | Method for producing resveratrol extracted from peanut root |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200510040625 CN1709846A (en) | 2005-06-17 | 2005-06-17 | Method for producing resveratrol extracted from peanut root |
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| Publication Number | Publication Date |
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| CN1709846A true CN1709846A (en) | 2005-12-21 |
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| CN 200510040625 Pending CN1709846A (en) | 2005-06-17 | 2005-06-17 | Method for producing resveratrol extracted from peanut root |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101215581B (en) * | 2008-01-18 | 2010-12-15 | 山东省花生研究所 | Method for preparing resveratrol by enzymolysis |
| CN101597214B (en) * | 2009-07-10 | 2012-04-25 | 山东省花生研究所 | Method for extracting resveratrol from peanut roots |
| CN103816214A (en) * | 2014-03-17 | 2014-05-28 | 漯河医学高等专科学校 | Application of peanut root extract in preparing medicines or foods for preventing and treating prostatic hyperplasia |
| WO2021004000A1 (en) * | 2019-07-10 | 2021-01-14 | 中国农业科学院农产品加工研究所 | Method for producing peanut oil rich in resveratrol |
-
2005
- 2005-06-17 CN CN 200510040625 patent/CN1709846A/en active Pending
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101215581B (en) * | 2008-01-18 | 2010-12-15 | 山东省花生研究所 | Method for preparing resveratrol by enzymolysis |
| CN101597214B (en) * | 2009-07-10 | 2012-04-25 | 山东省花生研究所 | Method for extracting resveratrol from peanut roots |
| CN103816214A (en) * | 2014-03-17 | 2014-05-28 | 漯河医学高等专科学校 | Application of peanut root extract in preparing medicines or foods for preventing and treating prostatic hyperplasia |
| WO2021004000A1 (en) * | 2019-07-10 | 2021-01-14 | 中国农业科学院农产品加工研究所 | Method for producing peanut oil rich in resveratrol |
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