CN1687789A - Common suction nozzle adjustable continuous liquid trasfer device - Google Patents

Common suction nozzle adjustable continuous liquid trasfer device Download PDF

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Publication number
CN1687789A
CN1687789A CN 200510068039 CN200510068039A CN1687789A CN 1687789 A CN1687789 A CN 1687789A CN 200510068039 CN200510068039 CN 200510068039 CN 200510068039 A CN200510068039 A CN 200510068039A CN 1687789 A CN1687789 A CN 1687789A
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China
Prior art keywords
suction nozzle
vent valve
air
valve
liquid
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Pending
Application number
CN 200510068039
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Chinese (zh)
Inventor
宋雪冬
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Individual
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Individual
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Priority to CN 200510068039 priority Critical patent/CN1687789A/en
Publication of CN1687789A publication Critical patent/CN1687789A/en
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Abstract

It is a kind of 'common suction nozzle - adjustable continuous pipette' which can both continuously transfer and conveniently get renewed making use of the simple suction nozzle. It fix the intake value (11) and the air evacuation value (14) into the seal cavity (10) on the base of air substitute axiom. Besides, an air evacuation value ejector pin (19) is set on one side of the main body cavity of the pipette machine; on the bottom of (19) there is an 'O' circle to seal it. After operating the button (1) to choose the transfer quantity, you should press the switch of the air evacuation value (18) to open the air evacuation value (14). Then press the operating button (1) to the second breakpoint, and at this time the solution absorbed reaches the maximum quantity this transfer machine can absorb. Then press the switch of the air evacuation value (18) to eject it and close the air evacuation value (14). After those, you should by steps press the operating button (1) to the first breakpoint, and then you can continually add the samples in the same amount. If the experiment needs different amounts, you can arbitrarily roll the operating button (1) to choose the transfer amount according to the needs to make continuous transfer in different amounts.

Description

The continuous pipettor of common suction nozzle one adjustable type
Technical field
The present invention relates to a kind of being applied in department's biochemical analysises such as hospital, chemical industry, scientific research and the sample survey, to liquid such as serum carry out accurately, the device of microsampling and liquid feeding.Especially, it only needs to use common suction nozzle, can finish and move liquid fast and accurately continuously.
Background technology
Present known pipettor, its principle have two kinds basically: a kind of is the principle of work of utilizing air displacement, makes to decide Cheng Yundong by piston in piston bush, produces negative pressure, and sucks and discharge the common pipettor of quantitative liquid work; Another kind is to utilize special syringe-type suction nozzle, has piston in the pull lever pull-up syringe of draw-in groove and suck liquid in pipettor, and then the journey of deciding by pull lever moves down again, discharges the continuous pipettor of the method work of quantitative liquid.In this pipettor of two types, the former can only carry out single and move liquid (after sucking liquid, disposable with the liquid quantitative discharge), can not move liquid continuously, (sample need be done a plurality of experiments simultaneously at current a large amount of combination experiment for this, for example " five indexes of hepatitis b ") in, then seem not only time-consuming but also require great effort.Though and the latter can move liquid continuously, because it is to utilize special syringe-type suction nozzle, be unfavorable for frequent replacing, only be applicable to the liquid that moves of reagent, and be not suitable for sample.
Summary of the invention
Can not move liquid continuously in order to solve current common pipettor, and the continuous pipettor that utilizes the syringe-type suction nozzle can easily not changed the problem of suction nozzle, the invention provides a kind of pipettor, can move liquid continuously, can can change easily by utilizing common suction nozzle again, to prevent the cross pollution of sample room.What it not only was applicable to the equivalent composite test moves liquid continuously, is applicable to the composite test of inequality too, thereby work efficiency is significantly improved.
The technical solution adopted for the present invention to solve the technical problems is: on the basis that utilizes the air displacement principle of work, in piston bush, install gas admittance valve and vent valve additional, in addition, side at the pipettor main cavity is provided with a vent valve ejector pin, and its below is provided with a round section joint ring to play sealing function.By pressing vent valve ejector pin switch opens vent valve, thereby make the exhaust passage unimpeded, reach the purpose of exhaust and imbibition.During work, earlier action button is pressed to the second halt position, thereby maximum liquid is sucked in the suction nozzle.After imbibition finishes, pressed vent valve ejector pin switch again, vent valve is closed under the effect of exhaust valve spring, makes the interior air of annular seal space and mouth awl isolated.At this moment, push button to the first halt again, the ejection effect of piston makes air in the annular seal space increase the pressure of vent valve, and vent valve is opened, and quantitatively the air of volume is discharged, and waits quantity of fluid in the suction nozzle thereby discharge.At this moment, piston stops to move down, and vent valve both sides air pressure reaches balance, and vent valve is closed under the effect of exhaust valve spring.Then, the unclamp operation button resets at the effect lower piston of back-moving spring.Because this moment, annular seal space was airtight, and its air pressure inside is reduced, extraneous air is pushed gas admittance valve open under the effect of atmospheric pressure, replenishes the air that annular seal space is discharged, and when its inner and outer air pressure equated, gas admittance valve cut out air admission hole under the effect of its spring.So far finish and move liquid for the first time.Repeat to press down action button to the first halt, can finish repeatedly equivalent and move liquid.When Multitest needs the inequality sample, can be at any time rotating operation button easily, select the corresponding stop fulcrum of corresponding accent amount draw-in groove, adjust and move liquid measure, can reach the purpose of moving liquid continuously equally.
The invention has the beneficial effects as follows, when same detected sample carries out multinomial equivalent or non-equivalent detection, all can move liquid continuously.And can change suction nozzle easily, thereby can obviously increase work efficiency by the suction nozzle ejector pin.
Description of drawings
The present invention is further described below in conjunction with drawings and Examples.
Fig. 1 is the longitudinal profile structural map of one embodiment of the present of invention.
Fig. 2 is the stereographic map (for the ease of observing its inner structure, the top is a cross-section structure) that (4) transfer measuring device among Fig. 1.
Fig. 3 is a corresponding part shell of transferring measuring device (4) one sides among this embodiment of Fig. 1, and there is display window its top.
Fig. 4 is the stereographic map of (2 1) stop among Fig. 1.
Among Fig. 1,1. action button, 2. suction nozzle ejector pin button, 3. 1. back-moving spring 4. transfers measuring device, 5. transfers the measuring device draw-in groove, 6. stop fulcrum, 7. back-moving spring 2., 8. annular seal space round section joint ring, 9. piston, 10. annular seal space, 11. gas admittance valves, 12. air admission hole, 13. inlet valve springs, 14. vent valves, 15. the mouth awl, 16. suction nozzle ejector pins, 17. handles, 18. the vent valve switch, 19. vent valve ejector pins, 20. piston ejector pins, 21. stop, 22. vent valve ejector pin spring, 23. vent valve ejector pin round section joint rings, 24. spring guides, 25. the vent valve retracing spring, 26. suction nozzles.
Among Fig. 2, after the numeral rotating operation button on accent measuring device surface makes and transfers measuring device to rotate, can once can move liquid measure by what display window showed.When a certain numeral is presented on the display window, be positioned at same track with its amount corresponding accent amount draw-in groove and stop fulcrum.
Among Fig. 3, when choose required move liquid measure after, transfer the respective digital on measuring device surface to show by the display window on this figure pipettor shell.
Among Fig. 4, the stop below is a right cylinder, and the centre has a hole that the piston ejector pin is passed through.
Embodiment
In Fig. 1, the accent measuring device (4) in action button (1) and the cavity and the piston (9) of below connect as one.By rotating operation button (1) accent measuring device (4) is rotated, thereby can select its 5 grades to transfer measuring device draw-in grooves (5).The degree of depth by draw-in groove can determine the degree of depth that piston moves down, thereby decision moves liquid measure, this pipettor can be made into as required 5 gears (for example 10,20,30,40,50 microlitres) of any 5 adjacent whole ten displacement liquid measures in the 10-1000 microlitre.When any a pair of symmetrical draw-in groove (5) is corresponding with two fulcrums (6) of below stop (21), after action button (1) presses down, transferring measuring device draw-in groove (5) to be displaced downwardly to stop fulcrum (6) is obstructed, loosen action button (1) it is resetted, the amount of liquid that this process can suck/discharge is this set amount.Transfer measuring device (4) when together rotating when rotating operation button (1) makes, the digital (see figure 2) on its five gear surfaces, top can be selected a gear one by one through display window (Fig. 3) demonstration of pipettor shell, and shown numeral is promptly represented the liquid measure of moving once.
Among Fig. 1, transferring the main body of measuring device (4) is a right cylinder (Fig. 2), has 5 pairs of symmetrical draw-in grooves (5), and by rotating operation button (1), it both can rotate in cavity, can move up and down again.
Fig. 4 is the stereographic map of stop among Fig. 1 (21).Its below is a right cylinder, and the centre has a hole that the piston ejector pin is passed through.Two arms are arranged on the right cylinder, and protrude in the right cylinder of below to both sides, stop can be fixed in the track of wall both sides, chamber by this overhang, it can only be moved up and down and can not rotate, contact with stop draw-in groove [among Fig. 1 (5)] by two arms, limit and move liquid measure.
Gas admittance valve among Fig. 1 (11), inlet valve spring (13), air admission hole (12) constitute compensated with air system (gas handling system) jointly, are located at a side of annular seal space bottom.This is one of this pipettor outstanding feature.
Among Fig. 1, vent valve switch (18), vent valve ejector pin (19), vent valve ejector pin spring (22), vent valve (14), vent valve retracing spring (25) and spring guide (24) thereof and below round section joint ring (23) thereof constitute the exhaust system of this pipettor jointly, vent valve (14) is located at the bottom of annular seal space, and its switch (18) is arranged at the below of handle (1 7) for easy to operate.This is another distinguishing feature of this pipettor.
Among Fig. 1, gas admittance valve (11), vent valve (14), annular seal space round section joint ring (8) and piston (9) are formed an annular seal space 10 jointly), this is groundwork of the present invention chamber.
In operating process, with pipettor transfer to required move liquid measure after, press vent valve switch (18) (be a self-locking pushbutton switch, pin voluntarily after pressing), stressed the moving down of vent valve ejector pin (19) again by then upspringing automatically.At this moment, vent valve (14) is opened under the ejection effect of vent valve ejector pin (19), and annular seal space (10) is communicated with mouth awl (15) inner chamber.Then, push button (1) carries out imbibition.Action button (1) is in the process that presses down, and at first compression reseting spring 1. (3) is obstructed when transferring accent amount draw-in groove (5) the contact stop fulcrum (6) of measuring device (4), and action button (1) present position is first halt.When action button continues to press down, 2. after (7), piston ejector pin (19) is obstructed end in contact annular seal space (10) wall upper end down the stressed compression reseting spring of stop (21).At this moment, action button (1) present position is second halt.The suction nozzle mouth is placed under the liquid level, loosen action button (1), liquid is sucked in the suction nozzle (26), at this moment, the maximum that liquid can suck for this pipettor that sucks.Then, keep suction nozzle under liquid level, pressing vent valve switch (18) once more makes it to upspring automatically, vent valve ejector pin (19) moves under vent valve ejector pin spring (22) effect, vent valve (14) resets under the effect of vent valve retracing spring (24), make annular seal space be sealing state, the imbibition process is finished.At this moment, push button to the first halt, the ejection effect of piston (9) makes the interior air of annular seal space (10) increase the pressure of vent valve, and vent valve (14) is opened, and quantitatively the air of volume is discharged, and waits quantity of fluid in the suction nozzle (26) thereby discharge.At this moment, annular seal space (10) internal gas pressure and ambient pressure reach balance, and vent valve (14) is closed under the effect of vent valve retracing spring (24).Then, unclamp operation button (1), back-moving spring 1. the effect lower piston (9) of (3) reset.Because annular seal space this moment (10) is airtight, after piston (9) resets its air pressure inside is reduced, extraneous air is pushed gas admittance valve (11) open under the effect of atmospheric pressure, replenish the air of discharging in the cavity, when its inner and outer air pressure equated, gas admittance valve (11) cut out air admission hole (12) under the effect of its spring (13).So far finish and move liquid for the first time.Repeat down press operation button (1) to first halt, can finish and repeatedly move liquid.
Specific operation process can be summarized as follows: after selecting to move liquid measure by action button (1), press vent valve switch (18), after action button (1) is pressed to the second halt imbibition, keep the suction nozzle mouth under liquid level and press vent valve switch (18) again and makes it to upspring.Then, mention pipettor, can repeat push button (1), carry out the continuous application of sample of equivalent to first halt.(for the test combinations of inequality, can be as required arbitrarily rotating operation button (1) select to move carry out inequality after the liquid measure move liquid continuously.) last, press suction nozzle ejector pin button (2), by the ejection effect of suction nozzle ejector pin (16) suction nozzle (26) is pushed, so far, the liquid that moves continuously of a duplicate samples is finished.

Claims (3)

1. one kind " common suction nozzle adjustable continuous liquid trasfer device " is characterized in that having: an exhaust system of being made up of vent valve, vent valve switch, vent valve ejector pin, vent valve ejector pin spring, exhaust valve spring and guide rod thereof; With a gas handling system of forming by air admission hole, gas admittance valve, inlet valve spring and guide rod thereof (compensated with air system).Method by " air displacement-compensation " is moved liquid.
2. " common suction nozzle adjustable continuous liquid trasfer device " according to claim 1 is characterized in that forming an annular seal space (piston bush) jointly by gas admittance valve, vent valve, annular seal space round section joint ring and piston.
3. according to claims 1 and claims 2 described " common suction nozzle adjustable continuous liquid trasfer device ", its annular seal space is separated by by vent valve and mouth awl inner chamber, is separated by by gas admittance valve and outside air.Constitute the circulation system of " discharging-compensation-discharging again-compensation again ... " of a liquid-to-air equivalent.
CN 200510068039 2005-05-09 2005-05-09 Common suction nozzle adjustable continuous liquid trasfer device Pending CN1687789A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN 200510068039 CN1687789A (en) 2005-05-09 2005-05-09 Common suction nozzle adjustable continuous liquid trasfer device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 200510068039 CN1687789A (en) 2005-05-09 2005-05-09 Common suction nozzle adjustable continuous liquid trasfer device

Publications (1)

Publication Number Publication Date
CN1687789A true CN1687789A (en) 2005-10-26

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Family Applications (1)

Application Number Title Priority Date Filing Date
CN 200510068039 Pending CN1687789A (en) 2005-05-09 2005-05-09 Common suction nozzle adjustable continuous liquid trasfer device

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101441223B (en) * 2008-12-29 2012-06-13 中国科学院长春光学精密机械与物理研究所 Precision trace sampling apparatus with mixing function
CN111589481A (en) * 2020-06-04 2020-08-28 向军 Clinical laboratory uses pipettor
CN111781381A (en) * 2020-07-23 2020-10-16 金华科生物技术河北有限公司 High-sensitivity C-reactive protein detection kit

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101441223B (en) * 2008-12-29 2012-06-13 中国科学院长春光学精密机械与物理研究所 Precision trace sampling apparatus with mixing function
CN111589481A (en) * 2020-06-04 2020-08-28 向军 Clinical laboratory uses pipettor
CN111781381A (en) * 2020-07-23 2020-10-16 金华科生物技术河北有限公司 High-sensitivity C-reactive protein detection kit

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