CN1650953A - Medicine for treating enteritis diarrhea and its preparation method - Google Patents

Medicine for treating enteritis diarrhea and its preparation method Download PDF

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Publication number
CN1650953A
CN1650953A CN 200410079592 CN200410079592A CN1650953A CN 1650953 A CN1650953 A CN 1650953A CN 200410079592 CN200410079592 CN 200410079592 CN 200410079592 A CN200410079592 A CN 200410079592A CN 1650953 A CN1650953 A CN 1650953A
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rhizoma
thick paste
polygoni paleachi
medicine
hours
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CN 200410079592
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Chinese (zh)
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杨本雷
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Individual
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Individual
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Abstract

A Chinese medicine in the form of particles for treating enteritis and diarrhea is prepared from 4 Chinese-medicinal materials including paleaceous knotweed rhizome, featherleaf rodgersflower rhizome, heroubill and atractylodes rhizome. Its preparing process is also disclosed.

Description

A kind of medicine for the treatment of enteritis, diarrhea and preparation method thereof
Technical field
The invention belongs to the prescription and the preparation method technical field of treatment enteritis and diarrhoea medicine.
Background technology
Existing treatment enteritis and diarrheal medicine are many on the market, but many medicines have side effect, seem slow on curative effect, and great majority treatment enteritis and diarrheal medicine production cost cause the medicine valency also high than higher.
Summary of the invention
What purpose of the present invention provided a kind of good effect in order to overcome the weak point that above-mentioned prior art exists just, has no side effect, production cost is low can treat medicine of enteritis, diarrhea and preparation method thereof.
The objective of the invention is to realize by following technical solution.
A kind of medicine for the treatment of enteritis, diarrhea, its component is: Rhizoma Polygoni Paleachi 25~40%, Rhizoma Rodgersiae 20~30%, old Herba Erodii 20~30%, Rhizoma Atractylodis 12~30%.Preparation method is: get Rhizoma Polygoni Paleachi selection, clean, pulverized 80~120 mesh sieves after the oven dry, collect the 75~80% standby of the powder that sieves; Rhizoma Atractylodis, Rhizoma Rodgersiae, Herba Erodii are chosen, clean, dry, pulverize respectively or after mixing, mix with remaining Rhizoma Polygoni Paleachi powder, with concentration is 65~80% soak with ethanol 1.5~2.5 hours, reuse concentration is 65~80% alcohol heating reflux 2~3 times, each 2~3 hours, merge the backflow after-filtration, the thick paste of relative density 〉=1.25 during with 45~55 ℃ of simmer down to temperature behind the filtrate recycling ethanol; Medicinal residues decoct with water 2~3 times, each 1.5~2.5 hours, merge decoction liquor and filtration, the thick paste of relative density 〉=1.25 during with 45~55 ℃ of filtrate simmer down to temperature, with this thick paste with after thick paste behind the alcohol reflux mixes, add standby Rhizoma Polygoni Paleachi fine powder,, make finished product through mixing, granulation, oven dry.
Think that the disease that per os imports human body into is called " noxious dampness " on the Yi nationality doctor, the damp per os is gone into the human body intestine and small intestine and is built up and do not change, and domination of damp pathogen is stranded discord, and then produces enteritis and cause diarrhoea.In the prescription of the present invention, Rhizoma Polygoni Paleachi is a polygonaceae plant Rhizoma Polygoni Paleachi Polygonum paleaceum wall. rhizome, has the alleviating distention in middle-JIAO therapeutic method to keep the adverse QI flowing downwards, dyspepsia disappears, the effect of the mass in the abdomen that disappears, Rhizoma Rodgersiae is the dry rhizome of saxifragaceae plant leatherleaf Rhizoma Rodgersiae Rodgersia pinnata Franch. or Rhizoma Rodgersiae R.sambucifolia Hemsl, can treat enteritis, bacillary dysentery, Herba Erodii is the dry aerial parts of the plant Granesbill Herb Geranium nepalensc sweet. of Mang cattle Seedling section, to escherichia coli, dysentery bacterium and multiple virus are inhibited, can promote the retrostalsis of caecum and antidiarrheal, Rhizoma Atractylodis are the dry rhizome of feverfew Rhizoma Atractylodis Atractylodes lancea (Thnub.) DC., the energy the spleen strengthening and damp drying is to staphylococcus aureus, bacillus pyocyaneus etc. have inhibitory action.The present invention's prescription adopts Rhizoma Polygoni Paleachi to suppress escherichia coli, dysentery bacterium, staphylococcus aureus etc. at the cause of disease, adopts the auxiliary Rhizoma Polygoni Paleachi treatment of Rhizoma Rodgersiae and Herba Erodii enteritis and dysentery, adopts Rhizoma Atractylodis to play the spleen strengthening and damp drying, controls wet sense and is stranded spleen, and gastral cavity abdomen painful abdominal mass expands, and vomits and diarrhoea etc.Have promoting tissue regeneration by removing blood stasis, restrain the function curative effect of astringent or styptic treatment for spontaneous sweating, hemostasis, antidiarrheal dysentery relieving, ascending the clear and descending the turbid invigorating the spleen and regulating the stomach.Because anti-diarrhea effect of the present invention is obvious, cure rate is high, production cost is low, without any side effects, prove suitable human body and take through clinical.Preparation method of the present invention is simple, and cost of manufacture is low.
Medicine of the present invention has carried out the clinical use of 100 examples and has observed in the period of Chuxiong, Yunnan Province state institute of traditional Chinese medicine is from 1989~1998, and wherein acute enteritis 48 examples are cured 37 examples, 9 examples that take a turn for the better, and 2 examples do not heal; Chronic enteritis 32 examples are cured 24 examples, 6 examples that take a turn for the better, and 2 examples do not heal; Acute gastroenteritis 15 examples are cured 10 examples, 4 examples that take a turn for the better, and 1 example does not heal; Anaphylaxis enteritis 5 examples are cured 4 examples, and 1 example takes a turn for the better; Cure rate 75%, total effective rate 95%.Clinical application is not for many years found toxic and side effects.
The specific embodiment
Embodiment one: get Rhizoma Polygoni Paleachi 25%, Rhizoma Rodgersiae 20%, Herba Erodii 25%, Rhizoma Atractylodis 30%.Get Rhizoma Polygoni Paleachi selection, clean, pulverized 120 mesh sieves after the oven dry, collect the 80% standby of the powder that sieves; The back pulverizing is chosen, cleans, dries, mixed to Rhizoma Atractylodis, Rhizoma Rodgersiae, Herba Erodii, mix with remaining Rhizoma Polygoni Paleachi powder, being that 65% ethanol is an amount of with concentration soaked 1.5 hours, reuse concentration is 65% alcohol heating reflux 3 times, each 2 hours, merge the backflow after-filtration, the thick paste of relative density 〉=1.25 during with 45 ℃ of simmer down to temperature behind the filtrate recycling ethanol; Medicinal residues decoct with water 2 times, each 1.5 hours, merge decoction liquor and filtration, the thick paste of relative density 〉=1.25 during with 45 ℃ of filtrate simmer down to temperature with after thick paste behind the alcohol reflux mixes, adds standby Rhizoma Polygoni Paleachi fine powder with this thick paste, through mixing, granulation, oven dry, make finished product.
Embodiment two: get Rhizoma Polygoni Paleachi 40%, Rhizoma Rodgersiae 28%, Herba Erodii 20%, Rhizoma Atractylodis 12%.Get Rhizoma Polygoni Paleachi selection, clean, pulverized 100 mesh sieves after the oven dry, collect the 75% standby of the powder that sieves; With Rhizoma Atractylodis, Rhizoma Rodgersiae, Herba Erodii selection, clean, after the oven dry, pulverize separately, mix with remaining Rhizoma Polygoni Paleachi powder, being that 80% ethanol is an amount of with concentration soaked 2.5 hours, reuse concentration is 80% alcohol heating reflux 2 times, each 3 hours, merge the backflow after-filtration, the thick paste of relative density 〉=1.25 during with 55 ℃ of simmer down to temperature behind the filtrate recycling ethanol; Medicinal residues decoct with water 3 times, each 2.5 hours, merge decoction liquor and filtration, the thick paste of relative density 〉=1.25 during with 55 ℃ of filtrate simmer down to temperature with after thick paste behind the alcohol reflux mixes, adds standby Rhizoma Polygoni Paleachi fine powder with this thick paste, through mixing, granulation, oven dry, make finished product.
Embodiment three: get Rhizoma Polygoni Paleachi 35%, Rhizoma Rodgersiae 25%, Herba Erodii 25%, Rhizoma Atractylodis 15%.Get Rhizoma Polygoni Paleachi selection, clean, pulverized 80 mesh sieves after the oven dry, collect the 78% standby of the powder that sieves; The back pulverizing is chosen, cleans, dries, mixed to Rhizoma Atractylodis, Rhizoma Rodgersiae, Herba Erodii, mix with remaining Rhizoma Polygoni Paleachi powder, being that 70% ethanol is an amount of with concentration soaked 2 hours, reuse concentration is 70% alcohol heating reflux 2 times, each 2 hours, merge the backflow after-filtration, the thick paste of relative density 〉=1.25 during with 50 ℃ of simmer down to temperature behind the filtrate recycling ethanol; Medicinal residues decoct with water 2 times, each 2 hours, merge decoction liquor and filtration, the thick paste of relative density 〉=1.25 during with 50 ℃ of filtrate simmer down to temperature with after thick paste behind the alcohol reflux mixes, adds standby Rhizoma Polygoni Paleachi fine powder with this thick paste, through mixing, granulation, oven dry, make finished product.

Claims (2)

1, a kind of medicine for the treatment of enteritis, diarrhea is characterized in that, its component is: Rhizoma Polygoni Paleachi 25~40%, Rhizoma Rodgersiae 20~30%, Herba Erodii 20~30%, Rhizoma Atractylodis 12~30%.
2, a kind of preparation method of medicine of treatment enteritis, diarrhea as claimed in claim 1 is characterized in that, preparation method is as follows: get Rhizoma Polygoni Paleachi selection, clean, pulverized 80~120 mesh sieves after the oven dry, collect the 75~80% standby of the powder that sieves; With Rhizoma Atractylodis, Rhizoma Rodgersiae, Herba Erodii selection, clean, oven dry, pulverize respectively or after mixing, mix with remaining Rhizoma Polygoni Paleachi powder, with concentration is 65~80% soak with ethanol 1.5~2.5 hours, reuse concentration is 65~80% alcohol heating reflux 2~3 times, each 2~3 hours, merge the backflow after-filtration, the thick paste of relative density 〉=1.25 during with 45~55 ℃ of simmer down to temperature behind the filtrate recycling ethanol; Medicinal residues decoct with water 2~3 times, each 1.5~2.5 hours, merge decoction liquor and filtration, the thick paste of relative density 〉=1.25 during with 45~55 ℃ of filtrate simmer down to temperature, behind the thick paste mixing behind this thick paste and the alcohol reflux, add standby Rhizoma Polygoni Paleachi fine powder,, make finished product through mixing, granulation, oven dry.
CN 200410079592 2004-11-30 2004-11-30 Medicine for treating enteritis diarrhea and its preparation method Pending CN1650953A (en)

Priority Applications (1)

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CN 200410079592 CN1650953A (en) 2004-11-30 2004-11-30 Medicine for treating enteritis diarrhea and its preparation method

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Application Number Priority Date Filing Date Title
CN 200410079592 CN1650953A (en) 2004-11-30 2004-11-30 Medicine for treating enteritis diarrhea and its preparation method

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CN1650953A true CN1650953A (en) 2005-08-10

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1857453B (en) * 2006-03-03 2010-05-12 延边大学 Chinese medicine composition for treating ulcerative colitis and its preparing method
CN101822721B (en) * 2009-08-19 2012-06-27 烟台大洋制药有限公司 Medicament for treating enteritis

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1857453B (en) * 2006-03-03 2010-05-12 延边大学 Chinese medicine composition for treating ulcerative colitis and its preparing method
CN101822721B (en) * 2009-08-19 2012-06-27 烟台大洋制药有限公司 Medicament for treating enteritis

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