CN1634939A - Supercritical CO2 extraction process for soya bean lecithin - Google Patents

Abstract

The invention discloses a process for extracting soya bean lecithin by supercritical CO2. It's purity may be 90% above, solvent dosage is small, and the products have high quality. The extracted soya bean lecithin can be applied in medical product development directly.

Description

A kind of supercritical CO 2Extract the method for soybean lecithin

[technical field]

The present invention relates to a kind of supercritical CO ₂Extract the method for soybean lecithin, belong to field of light industry.

[background technology]

Phosphatide is the general name that contains the lipoid of phosphate radical, and main component has compositions such as phosphatidylcholine (Yelkin TTS), phosphatidylethanolamine (kephalin), phosphatidylinositols (lipositol) and phosphatidic acid, phosphatidylserine.Phosphatide is the indispensable moiety of animal vegetable tissue; it is one of biomembranous basic substance; microbial film is not only the protection barrier of cell; also be that living matter is synthetic, the important structure of metabolism, transportation; phosphatide is the basic substance of life with the structure of its rule and the normal configuration and the function of character assurance cell.Phosphatide also is the important substance that nerve information forms and transmits in the brain, accounts for 30% of brain weight.Phosphatide plays emulsifying effect in blood, dissolving cholesterol makes it become suspended state in blood effectively, avoids deposition, guarantees the normal circulation of blood.The phosphatide solubilized is eliminated intravital lipid peroxide, active cells function.Because the above-mentioned functions characteristic of phosphatide, make phosphatide have regulating blood fat, improve effect such as remember, delay senility.Simultaneously without any side effects, be a kind of health care pharmaceuticals that have the exploitation future.

In the phosphatide active function, what play an important role is exactly phosphatidylcholine---Yelkin TTS, its purity is high more, and functional strong more, the researchist is studying its purifying process always, in the hope of obtaining the Yelkin TTS of high quality, high functionality, but traditional method all is to adopt solvent method to extract, production cost height not only, and the solvent usage quantity is big, product purity also can only reach about 70%, can only produce protective foods.Supercritical CO ₂Technology is extracted Yelkin TTS since nineteen eighty-three (Heigel, W.and R.Hueschens.US Patent 1983,4367178).Because the viscosity of phosphatide is big, particularly remove certain gauging after, phosphatide becomes paste substantially, makes that using supercritical technology produces high-purity phospholipid and be restricted (Wang Xingguo etc., Chinese oil, 2000,25:29～31).Method commonly used at present is to add inert matter (crossing the peaceful people in limit etc., clear and 62-179351) to increase CO ₂Perviousness in phosphatide, as edible fibre, or with high temperature (90～100 ℃) and high pressure (80～100Mpa) (Eggors K.and H.Wangner, J.SupercriticalFluids, 1993,6:31) CO under the condition ₂Greasy solubleness increased greatly prepare high-purity phospholipid.But because its use cost height, equipment complexity and High Temperature High Pressure make supercritical CO to shortcomings such as the active certain destructions of phosphatide ₂Technology is used and is restricted.

[summary of the invention]

[technical problem that will solve]

The purpose of this invention is to provide a kind of supercritical CO ₂Technology is extracted the method for soybean lecithin, and its purity can reach more than 90%, and the solvent usage quantity is few, and the quality product height is functional strong.The soybean lecithin that is extracted can directly apply to the exploitation of pharmaceutical prod.

[technical scheme]

Task of the present invention realizes as follows:

A) preheating: powdered soy bean phosphatide is added in the extractor, be preheating to 30～50 ℃;

B) extract: with the CO of 10～25L/h ₂Flow, the ethanol entrainment agent of adding 5～15% (weight ratios), at 30～50 ℃, about 25Mpa pressure extracts 2～3h down;

C) separate: extracting solution separates in separator under 20 ℃～40 ℃ conditions at about 5Mpa, reclaims CO ₂

D) extracting solution adds vacuum tank, and at 40～60 ℃, 0.04～0.1Mpa reclaims ethanol down, obtains containing the high purity lecithin extract.

The present invention can also put into vacuum drying oven with the said extracted thing, and is at 40～60 ℃, dry under 0.02～0.08Mpa condition; Dried extract packing is finished product.

[beneficial effect]

The present invention has following advantage:

1. the product purity height reaches more than 90%, and is functional strong;

2. not only can produce protective foods, also can be applicable to the exploitation of medical supplies;

3. production process CO ₂Nontoxic, recyclable utilization has reduced the use of organic solvent, more Environmental Safety.

Following specific embodiment further specifies the present invention, but does not limit the present invention with this.

[specific embodiment]

Embodiment 1

Get the 100g powder lecithin, add in the extractor, be preheated to 40 ℃, CO ₂Mix with 5% (weight ratio) ethanol entrainment agent and to be forced into about 25Mpa, CO ₂Flow 10L/h, by extractor, extracting solution in separating tank 30 ℃, Separation and Recovery CO under about 5Mpa condition ₂Extract 3h continuously.Extracting solution adds in the vacuum tank, at 40 ℃, reclaims solvent under the 0.04Mpa condition, obtains the Yelkin TTS extract, purity 92%.The said extracted thing is put into vacuum drying oven, and at 40 ℃, 0.02Mpa is dry down, and dried extract packing is finished product.

Embodiment 2

Get the 100g powder lecithin, add in the extractor, be preheated to 50 ℃, CO ₂Mix with 10% (weight ratio) ethanol entrainment agent and to be forced into about 25Mpa, CO ₂Flow 15L/h, by extractor, extracting solution in separating tank 40 ℃, Separation and Recovery CO under about 5Mpa condition ₂Extract 3h continuously.Extracting solution adds in the vacuum tank, at 60 ℃, reclaims solvent under the 0.1Mpa condition, obtains the Yelkin TTS extract, purity 93%.The said extracted thing is put into vacuum drying oven, and at 60 ℃, 0.07Mpa is dry down, and dried extract packing is finished product.

Embodiment 3

Get the 100g powder lecithin, add in the extractor, be preheated to 40 ℃, CO ₂Mix with 15% (weight ratio) ethanol entrainment agent and to be forced into about 25Mpa, CO ₂Flow 25L/h, by extractor, extracting solution in separating tank 30 ℃, Separation and Recovery CO under about 5Mpa condition ₂Extract 3h continuously.Extracting solution adds in the vacuum tank, at 50 ℃, reclaims solvent under the 0.07Mpa condition, obtains the Yelkin TTS extract, purity 92%.The said extracted thing is put into vacuum drying oven, and at 50 ℃, 0.04Mpa is dry down, and dried extract packing is finished product.

Claims (2)

1, a kind of supercritical CO ₂Extract the method for soybean lecithin, it is characterized in that described method comprises following step:

A) preheating: powdered soy bean phosphatide is added in the extractor, be preheating to 30～50 ℃;

B) extract: with the CO of 10～25L/h ₂Flow, the ethanol entrainment agent of adding 5～15% (weight ratios), at 30～50 ℃, about 25Mpa pressure extracts 2～3h down;

C) separate: extracting solution separates in separator under 20 ℃～40 ℃ conditions at about 5Mpa, reclaims CO ₂

D) extracting solution adds vacuum tank, and at 40～60 ℃, 0.04～0.1Mpa reclaims ethanol down, obtains containing the high purity lecithin extract.

2, method according to claim 1 is characterized in that and described extract can be put into vacuum drying oven, and is at 40～60 ℃, dry under 0.02～0.08Mpa condition.