CN1634116A - 司他夫定缓释片剂及其制备方法 - Google Patents
司他夫定缓释片剂及其制备方法 Download PDFInfo
- Publication number
- CN1634116A CN1634116A CN 200410087658 CN200410087658A CN1634116A CN 1634116 A CN1634116 A CN 1634116A CN 200410087658 CN200410087658 CN 200410087658 CN 200410087658 A CN200410087658 A CN 200410087658A CN 1634116 A CN1634116 A CN 1634116A
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- CN
- China
- Prior art keywords
- stavudine
- sustained release
- pharmaceutic adjuvant
- hypromellose
- release tablet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
实施例 | 片芯 | 包衣片释放度% | 稳定性(40℃、75%RH,杂质%) | ||||||
外观 | 脆碎度 | 2H | 4H | 8H | 24H | 1月 | 2月 | 3月 | |
1 | 白色 | 0.23 | 21.36 | 45.23 | 82.96 | 99.05 | 0.26 | 0.31 | 0.32 |
2 | 白色 | 0.31 | 19.25 | 42.36 | 78.36 | 100.01 | 0.28 | 0.30 | 0.33 |
3 | 白色 | 0.25 | 25.36 | 48.57 | 86.42 | 99.65 | 0.24 | 0.29 | 0.32 |
4 | 白色 | 0.22 | 23.16 | 39.89 | 78.96 | 98.24 | 0.27 | 0.31 | 0.35 |
5 | 白色 | 0.24 | 20.35 | 43.28 | 84.16 | 102.31 | 0.22 | 0.29 | 0.34 |
6 | 白色 | 0.35 | 24.82 | 47.53 | 85.24 | 102.29 | 0.29 | 0.30 | 0.34 |
Claims (6)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB2004100876587A CN100548309C (zh) | 2004-11-24 | 2004-11-24 | 司他夫定缓释片剂 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CNB2004100876587A CN100548309C (zh) | 2004-11-24 | 2004-11-24 | 司他夫定缓释片剂 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1634116A true CN1634116A (zh) | 2005-07-06 |
CN100548309C CN100548309C (zh) | 2009-10-14 |
Family
ID=34847479
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CNB2004100876587A Expired - Fee Related CN100548309C (zh) | 2004-11-24 | 2004-11-24 | 司他夫定缓释片剂 |
Country Status (1)
Country | Link |
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CN (1) | CN100548309C (zh) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8603520B2 (en) | 2003-06-26 | 2013-12-10 | Intellipharmaceutics Corp. | Oral multi-functional pharmaceutical capsule preparations of proton pump inhibitors |
CN104306340A (zh) * | 2014-10-27 | 2015-01-28 | 哈尔滨商业大学 | 一种别嘌醇缓控释微粒及其制备方法 |
US9078827B2 (en) | 2006-05-12 | 2015-07-14 | Isa Odidi | Pharmaceutical composition having reduced abuse potential |
US9561188B2 (en) | 2006-04-03 | 2017-02-07 | Intellipharmaceutics Corporation | Controlled release delivery device comprising an organosol coat |
CN107875133A (zh) * | 2017-12-11 | 2018-04-06 | 湖南省湘中制药有限公司 | 一种丙戊酸镁缓释片及其制备工艺 |
US10064828B1 (en) | 2005-12-23 | 2018-09-04 | Intellipharmaceutics Corp. | Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems |
CN109481420A (zh) * | 2018-12-03 | 2019-03-19 | 江苏四环生物制药有限公司 | 一种甲钴胺缓释胶囊 |
US10624858B2 (en) | 2004-08-23 | 2020-04-21 | Intellipharmaceutics Corp | Controlled release composition using transition coating, and method of preparing same |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4892742A (en) * | 1985-11-18 | 1990-01-09 | Hoffmann-La Roche Inc. | Controlled release compositions with zero order release |
GB8616669D0 (en) * | 1986-07-09 | 1986-08-13 | Merk Sharpe & Dohme Ltd | Pharmaceutical compositions |
IT1266565B1 (it) * | 1993-07-22 | 1997-01-09 | Ct Lab Farm Srl | Composizioni farmaceutiche a rilascio controllato a base di uno o piu' sali farmaceuticamente accettabili dell'acido gamma-idrossi-butirrico. |
IL151475A0 (en) * | 2000-03-30 | 2003-04-10 | Bristol Myers Squibb Co | Beadlets containing stavudine |
-
2004
- 2004-11-24 CN CNB2004100876587A patent/CN100548309C/zh not_active Expired - Fee Related
Cited By (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8802139B2 (en) | 2003-06-26 | 2014-08-12 | Intellipharmaceutics Corp. | Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient |
US9636306B2 (en) | 2003-06-26 | 2017-05-02 | Intellipharmaceutics Corp. | Proton pump-inhibitor-containing capsules which comprise subunits differently structured for a delayed release of the active ingredient |
US8603520B2 (en) | 2003-06-26 | 2013-12-10 | Intellipharmaceutics Corp. | Oral multi-functional pharmaceutical capsule preparations of proton pump inhibitors |
US10624858B2 (en) | 2004-08-23 | 2020-04-21 | Intellipharmaceutics Corp | Controlled release composition using transition coating, and method of preparing same |
US10064828B1 (en) | 2005-12-23 | 2018-09-04 | Intellipharmaceutics Corp. | Pulsed extended-pulsed and extended-pulsed pulsed drug delivery systems |
US9561188B2 (en) | 2006-04-03 | 2017-02-07 | Intellipharmaceutics Corporation | Controlled release delivery device comprising an organosol coat |
US10960077B2 (en) | 2006-05-12 | 2021-03-30 | Intellipharmaceutics Corp. | Abuse and alcohol resistant drug composition |
US9078827B2 (en) | 2006-05-12 | 2015-07-14 | Isa Odidi | Pharmaceutical composition having reduced abuse potential |
US10632205B2 (en) | 2006-05-12 | 2020-04-28 | Intellipharmaceutics Corp | Pharmaceutical composition having reduced abuse potential |
CN104306340B (zh) * | 2014-10-27 | 2017-07-04 | 哈尔滨商业大学 | 一种别嘌醇缓控释微粒及其制备方法 |
CN104306340A (zh) * | 2014-10-27 | 2015-01-28 | 哈尔滨商业大学 | 一种别嘌醇缓控释微粒及其制备方法 |
CN107875133A (zh) * | 2017-12-11 | 2018-04-06 | 湖南省湘中制药有限公司 | 一种丙戊酸镁缓释片及其制备工艺 |
CN109481420A (zh) * | 2018-12-03 | 2019-03-19 | 江苏四环生物制药有限公司 | 一种甲钴胺缓释胶囊 |
Also Published As
Publication number | Publication date |
---|---|
CN100548309C (zh) | 2009-10-14 |
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Owner name: NORTHEAST PHARMACEUTICAL GROUP CO., LTD. Free format text: FORMER OWNER: NORTHEAST PHARMACEUTICAL PLANT Effective date: 20100419 |
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Free format text: CORRECT: ADDRESS; FROM: 110026 NO.37, ZHONGGONG NORTH STREET,TIEXI DISTRICT, SHENYANG CITY, LIAONING PROVINCE TO: 110026 NO.37,ZHONGGONG NORTH STREET, TIEXI DISTRICT, SHENYANG CITY |
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Effective date of registration: 20100419 Address after: 110026, No. 37, North Street, heavy industry, Tiexi District, Shenyang Patentee after: Northeast Pharmaceutical Group Co., Ltd. Address before: 110026, No. 37, North Street, heavy industry, Tiexi District, Liaoning, Shenyang Patentee before: Dongbei Pharmaceutical Factory |
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CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20091014 Termination date: 20181124 |
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CF01 | Termination of patent right due to non-payment of annual fee |