CN1628755A - Quick effective medicine specified for treating drug resistant tuberculosis - Google Patents

Abstract

The invention provides a quick effective medicine specified for treating drug resistant tuberculosis, which is prepared from traditional medicinal herbs including roor of sessile stemona 10-30 parts, root of red rooted saliva 10-30 parts, donkey-hide gelatin 10-30 parts, radix scrophulariae 25-75 parts.

Description

Treatment Drug resistance tuberculosis quick specific medicine

Technical field

The present invention relates to a kind of treatment Drug resistance tuberculosis quick specific medicine, cure the medicine technical field in belonging to.

Background technology

Tuberculosis is the infectious disease that is caused by tubercule bacillus, and wherein mycobacterium tuberculosis causes pulmonary tuberculosis by droplet transmission; Mycobacterium bovis causes bone tuberculosis by not disinfectant milk propagation.Tuberculosis was once making medical circle feel simply helpless, and Germany scientist Robert on the 24th section conspicuously announced that mankind have found tubercule bacillus up to March in 1882, had just brought hope to controlling tuberculosis worldwide.In order to commemorate this great discovery, simultaneously also for causing the concern of the public to the tuberculosis problem, nineteen eighty-two is under World Health Organization (WHO) and the common proposal of international prevention tuberculosis and pulmonary disease alliance, being decided to be " World Tuberculosis Prevention and Cure Day " annual March 24.

Since the nineties, it is believed that the tuberculosis of effectively controlling and be bordering on disappearance, after quiet decades, staged a comeback again, and wreak havoc the whole world with the very swift and violent impetus in some areas.According to incompletely statistics, in the period of 1993 to 1996, global tuberculosis case increases by 13%.At present have the population that accounts for the world 1/3 to infect tulase approximately, the existing tuberculosis patient in the whole world is about 2,000 ten thousand, and annual neopathy 8,000,000 to 1,000 ten thousand people die from about 3,000,000 people of tuberculosis, and wherein 100,000 people are children.Tuberculosis has become the No.1 killer in the infectious disease.If do not take control measure immediately, estimate that the whole world will have 9,000 ten thousand cases to take place in 10 years, 3,000 ten thousand people's death, 300,000,000 healthy people are subjected to tubercle bacillus affection.

The research worker of Harvard University's medical college is said, after health official announced before 6 years that tuberculosis is global crisis, various medicines has all been produced drug-fast fatal tuberculosis pathogenic bacteria just to exceed the speed propagation that people expect.

In the meeting of " Drug resistance tuberculosis is to the influence in the whole world " held in New York, the medical research personnel are called this phenomenon " artificial problem " in a report, because there was not this problem before 50 years.They say that this " multiple medicine being produced the tuberculosis of drug resistance effect " finds that in 104 countries wherein great majority are developing countries, but nowadays the danger that propagates into West Europe and north america are arranged also.

1993, World Health Organization (WHO) gave the alarm to the whole world, by air borne, the antibacterial of---especially influencing pulmonary---has become a global crisis almost can to influence the various tissues of human body.The whole world has 8,000,000 people to infect tuberculosis every year approximately, and 2,000,000 people die from tuberculosis.

The main author of this report, Borrow doctor Fa Mo of Harvard University's medical college say: " to the rapid spread lungy that multiple medicine develops immunity to drugs, be the airplane crash of public health field maximum.When the patient stopped to treat or do not carry out enough correct Drug therapys, disease will develop immunity to drugs to medicine, and new Drug resistance fungus strain is spread ".

Treated tuberculosis for the domestic past, patient will take 4 kinds of medicines, will take 16 tablets of medicines every day.Take 9 tablets of medicines every day through changing into again after 2 months, obey 4-6 month.The not only loaded down with trivial details and trouble of such result, patient can't adhere to, and makes tulase form Drug resistance, is difficult to cure.

Summary of the invention

Technical assignment of the present invention is at above weak point, and providing a kind of has significant curative effect at each paratuberculosis, and can solve the treatment Drug resistance tuberculosis quick specific medicine of present tuberculosis Drug resistance problem.

The present invention is according to motherland's theory of Chinese medical science, in conjunction with pathogenesis lungy and Therapeutic Principle, based on anti-inflammation and sterilization, nutrition body, select for use the pure natural Chinese herbal medicine by a certain percentage compatibility make.

Medium-height grass prescription used in the present invention is separated as follows:

The Radix Stemonae: nature and flavor sweetness and bitterness, tepor, go into lung meridian.

Function cures mainly: gentle lung qi, cough-relieving, parasite killing.Control the cough due to wind and cold, cough for hundred mouthfuls, pulmonary tuberculosis, old cough with asthma.

Radix Salviae Miltiorrhizae: nature and flavor hardship, tepor, go into the heart, Liver Channel.

Function cures mainly: blood circulation promoting and blood stasis dispelling, calming heart and tranquilizing mind, evacuation of pus pain relieving.

Colla Corii Asini: nature and flavor are sweet, flat, go into lung, liver, kidney channel.

Function cures mainly: control blood deficiency, cough due to consumptive disease.

Radix Scrophulariae: the nature and flavor hardship is salty, cool, goes into lung, kidney channel.

Function cures mainly: YIN nourishing, pathogenic fire reducing, relieving restlessness, detoxifcation.Control the calentura excessive thirst, send out speckle, the hectic fever due to YIN-deficiency consumptive fever, it is not peaceful to sleep night, spontaneous sweating, constipation is hindered in Tianjin, laryngopharynx swelling and pain.

Treatment Drug resistance tuberculosis quick specific medicine, it is to be made by the following weight proportion raw material:

Radix Stemonae 10-30 part, Radix Salviae Miltiorrhizae 10-30 part

Colla Corii Asini 10-30 part, Radix Scrophulariae 25-75 part

A preferential proportioning of the present invention is:

Radix Stemonae 15-25 part, Radix Salviae Miltiorrhizae 15-25 part

Colla Corii Asini 15-25 part, Radix Scrophulariae 40-60 part

Best proportioning of the present invention is:

20 parts of the Radixs Stemonae, 20 parts of Radix Salviae Miltiorrhizaes

20 parts in Colla Corii Asini, 50 parts of Radix Scrophulariae

Treatment Drug resistance tuberculosis quick specific medicine of the present invention is compared with prior art, and its outstanding effect is:

1, drug effect is obvious, and the cure rate height is treated widely, can treat various tuberculosis.

2, curing the back does not have recurrence, and stability is high.

3, at present Drug resistance tuberculosis significant curative effect is arranged.

The specific embodiment

Embodiment 1:

30 parts of the Radixs Stemonae, 20 parts of Radix Salviae Miltiorrhizaes

20 parts in Colla Corii Asini, 60 parts of Radix Scrophulariae

Embodiment 2:

30 parts of the Radixs Stemonae, 10 parts of Radix Salviae Miltiorrhizaes

30 parts in Colla Corii Asini, 40 parts of Radix Scrophulariae

Embodiment 3:

25 parts of the Radixs Stemonae, 25 parts of Radix Salviae Miltiorrhizaes

20 parts in Colla Corii Asini, 40 parts of Radix Scrophulariae

Embodiment 4:

15 parts of the Radixs Stemonae, 25 parts of Radix Salviae Miltiorrhizaes

20 parts in Colla Corii Asini, 50 parts of Radix Scrophulariae

Embodiment 5:

20 parts of the Radixs Stemonae, 20 parts of Radix Salviae Miltiorrhizaes

20 parts in Colla Corii Asini, 50 parts of Radix Scrophulariae

Be suitable for disease: pulmonary tuberculosis, bone tuberculosis, lymphoid tuberculosis and other tuberculosis.

Instructions of taking: oral; Every day, twice usefulness was decocted in water for oral dose.

For showing the therapeutic effect of the present invention, select 100 routine tuberculosis cases to treat observation to tuberculosis disease: male's 68 examples, women's 32 examples, wherein the age minimum is 8 years old, the oldest 72 years old.The course of treatment is the longest 1 year, and is the shortest 23 days, and the patient more than 95% thinks that this medical instrument has unique curative effect.

One, diagnostic criteria:, in all meeting, Western medicine diagnose and Chinese medical discrimination standard, include case in according to " Chinese and western medicine diagnostics " contained clinical symptoms diagnostic criteria lungy.

Two, observational technique: require before taking medicine to fill in case history, so that the clinical symptoms before and after the contrast therapy.

Three, medication: each 125g medicine, twice usefulness is decocted in water for oral dose sooner or later, and 23 days is a course of treatment.

Four, criterion of therapeutical effect

1, cure: the clinical symptoms complete obiteration, main doctor trained in Western medicine physical and chemical index inspection is normal.

2, remarkable: all clinical symptoms is eliminated or the cardinal symptom elimination, and physical and chemical index is normal substantially.

3, invalid: symptom does not have improvement, with the no significant change of comparing before the treatment.

Five, observe conclusion:

The age men and women cures remarkable invalid cure rate

Below 20 years old 53 8--100%

20-30 year 82 10--100%

30-40 year 28 22 50--100%

40-50 year 414 1-80%

50-60 year 10 10 18 2-90%

60-70 year 5-4 1-80%

More than 70 years old 111 1-50%

The result shows, cures 95 examples, 5 examples evident in efficacy, invalid 0 example, cure rate 95%, total effective rate 100%.

Five, typical clinical case:

1, surplus Fushan Mountain village, Mengyin County Gao Dou town, the blue 36 years old Shandong Province of woman of Tang Gui

Suffer from bone tuberculosis for many years, two lower limb disabilities, the therapeutic effect of being in is not obvious.

Patient fell ill in nineteen eighty-two, mainly showed as two lower limb pains, low grade fever, perspired night, and health is day by day become thin, by the injection streptomycin etc. the antituberculosis drugs treat DeGrain, two lower limb became lame to 88 years, distortion, the difficulty of walking, causing lower limb disability then can not stand, and begins to take this prescription at the beginning of 90 to control medicine, restrain every days 125, sooner or later twice usefulness is decocted in water for oral dose, after 65 days, and low grade fever's transference cure of perspiring, two lower limb pains disappear, and former left lower extremity is sent out symptom cool and also disappeared.

Diagnosis: two tuberculosis of bones of lower extremity

2, so-and-so man 13 years old Shandong Zhao Yu village, area just outside a city gate, Mengyin County town of Xue

It is surplus half a year to suffer from lymphoid tuberculosis.

Patient fell ill in 89 years, neck, axil, a plurality of lymphadenectasis in groin many places, and how tame hospital diagnosis is doubtful Hokdkin disease, satisfy hospitalization, nothing is clearly better behind the first quarter moon, takes this prescription and controls medicine, restrain every days 100, and twice usefulness is decocted in water for oral dose sooner or later, after 13 days, body temperature descends, dose is strengthened in the back, and restrain every days 125, and front and back are after totally 23 days, the lymph node of all enlargements all disappears, and the state of an illness does not have recurrence after half a year.

Diagnosis: multiple lymphoid tuberculosis

3, pass controlling county town, great male 38 years old Shandong and close the town

Right cervical lymph node enlargement, summer, ulceration was suppurated.

Patient began right cervical lymph node enlargement in 1963, summer, ulceration was suppurated, and heal all the other seasons voluntarily, used other anti-tuberculosis drugs treatments, and DeGrain is taken this prescription and controlled medicine, and after 24 days, suppurating stops, and observed and did not have recurrence in 1 year.

Diagnosis: lymphoid tuberculosis

4, Huangxian county, the beautiful women 28 years old Shandong of Wang Xiao is all by tile village, town

Suffered from the left neck lymphoid tuberculosis in 98 years, the same year is in the hospital surgical excision of area, Yantai.

Patient excises edge of a knife disunion in back 1 year from suffering from lymphoid tuberculosis at area, Yantai hospital surgical, and it is more than to suppurate, and takes the other treatment means invalid, and rear to be in a bad way is taken this prescription and controlled medicine, and every day is by 125 grams, sooner or later with being decocted in water for oral dose recovery from illness about 70 days.

Diagnosis: lymphoid tuberculosis operation sequela

5, become certain 72 years old Shandong of man Mengyin County hospital

Cough, uncomfortable in chest

Patient was in morbidity in 87 years, and cough was uncomfortable in chest at that time, when serious the haematemesis symptom was arranged, and was diagnosed as pulmonary tuberculosis, used other antituberculosis drugs treat not have obvious improvement, took this prescription in 95 years to control medicine, and gram decoction sooner or later every days 125 was fully recovered after April, did not have recurrence in 6 years.

Diagnosis: pulmonary tuberculosis (8 years)

6,45 years old Shandong of Lu man Mengyin County Commission of Politics and Law

Cough, uncomfortable in chest, the moon of spitting blood is surplus

Patient falls ill at the beginning of 95, and with cough, and symptom uncomfortable in chest, and it is month surplus to spit blood, and cures to county hospital, takes other anti-tuberculosis drugs and does not have positive effect cooperates and takes this prescription and control medicine and fully recover after 50 days.

Diagnosis: pulmonary tuberculosis

7,32 years old people from Datong of Wang woman

Cough is become thin

Patient was in morbidity in 98 years, and cough was uncomfortable in chest at that time, had a low fever, day by day become thin, be pulmonary tuberculosis to hospital diagnosis, can not be restored for a long time with other antituberculosis drugs treat, after take this prescription and control medicine, fully recover after 5 months.(because of in be interrupted medicine about 1 week, the state of an illness has repeatedly, has influenced therapeutic effect)

Diagnosis: pulmonary tuberculosis

8, Huangxian county, Wang 72 years old Shandong of man is all by tile village, town

Cough, uncomfortable in chest, feel suffocated

Patient chest pain occurs in December, 2003, cough, and symptom such as feel suffocated is checked to be diagnosed as tuberculous pleuritis, and is treated, and leaves hospital after drawing water, take other anti-tuberculosis drugs; But after this state of an illness and is in hospital and was begun to take this prescription in 1,2004 year and control medicine repeatedly, every days 125 gram, twice usefulness is decocted in water for oral dose sooner or later, fully recovers after March, does not have recurrence so far.

Diagnosis: tuberculous pleuritis

Claims (3)

1, treatment Drug resistance tuberculosis quick specific medicine is characterized in that it is to be made by the following weight proportion raw material:

Radix Stemonae 10-30 part, Radix Salviae Miltiorrhizae 10-30 part

Colla Corii Asini 10-30 part, Radix Scrophulariae 25-75 part

2, treatment Drug resistance tuberculosis quick specific medicine according to claim 1 is characterized in that it is to be made by the following weight proportion raw material:

Radix Stemonae 15-25 part, Radix Salviae Miltiorrhizae 15-25 part

Colla Corii Asini 15-25 part, Radix Scrophulariae 40-60 part

3, treatment Drug resistance tuberculosis quick specific medicine according to claim 1 is characterized in that it is to be made by the following weight proportion raw material:

20 parts of the Radixs Stemonae, 20 parts of Radix Salviae Miltiorrhizaes

20 parts in Colla Corii Asini, 50 parts of Radix Scrophulariae