CN1415307A - Xiaobiling vaginal suppository - Google Patents
Xiaobiling vaginal suppository Download PDFInfo
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- CN1415307A CN1415307A CN 02137325 CN02137325A CN1415307A CN 1415307 A CN1415307 A CN 1415307A CN 02137325 CN02137325 CN 02137325 CN 02137325 A CN02137325 A CN 02137325A CN 1415307 A CN1415307 A CN 1415307A
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- contraceptive
- xiaobiling
- pessary
- vaginal suppository
- iodine
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Abstract
A vaginal suppository for disinfecting and contraception is prepared from nonoxinol, povidone-iodine, water and polyvinyl alcohol. It features high effect.
Description
Affiliated technical field
'Xiao Biling ' pessary of the present invention relates to a kind of Recipe of external-use medicine and dosage form, belongs to the pharmaceutical technical field.
Background technology
Phenomenon such as reproductive tract infection, condom receptance are undesirable and pregnant before marrige has become current social undisputable fact, seriously influences the numerous common people's healthy reproduction and social stability.A kind of control reproductive tract infection external applied contraceptive that has concurrently of market demand is as alternative.Present both at home and abroad progress is as follows: be the product development of control reproductive tract infection on the one hand; Be the development of spermicide on the other hand; Be the research that has control reproductive tract infection external contraceptive product concurrently in addition.The domestic market, it is a feast for the eyes that the women protects cloudy series of products.As JIEERYIN XIYE, for a long time cleaning/disinfecting washing liquid, clean health (woman woman cleaning solution), protect cloudy sterilization emulsion, Kang Nijie, clean cloudy A number, like to ask the cloudy cleaning solution of board skin, cloudy Thailand of skin, BF women's cleaning solution, beautiful feminine care liquid, the clean health of Lan Zuyin, the clean health lotion of natural the moon, source health hall FUYINJIE washing liquid, the acetic acid chlorine tens kinds of sterile products such as pyridine solution of spoiling.Its effective ingredient is chloride, iodine, ozone, peracetic acid, glutaraldehyde, quaternary ammonium salt and herbaceous plant class disinfectant basically.Their each tool advantages: disinfecting powers such as chlorine-containing disinfectant, ozone, peracetic acid and hydrogen peroxide are stronger; Strand quaternary ammonium salt and draft class are low effect disinfectantses.Play a part aspect healthy positive the human reproduction.Product as for molding on the contraception produce market of family planning mainly concentrates on following several respects: block pregnant path contraceptive method 1.: as various condoms, and contraceptive diaphragm, cervical cap and condom etc.; 2. give the hormone medicine contraceptive method: comprise various long-acting and fugitive contraceptive, fugitive oral contraceptive use is the most extensive in the wherein lady's hormone medicine, long acting injectable contraceptives and subdermal implants are used also more and more extensive, also have products such as pessary in addition, the research of men's hormonal contraceptive is very active, but is applied to clinical needing time; 3. ovulation back fertility adjusting method contraception: this respect intrauterine device is the most outstanding, and 40% is to use intrauterine device in the used contraceptive device of Chinese Mr. and Mrs, and pregnancy vaccine also is the present important research field of contraceptive techniques in the world; 4. sperimicide method: be generally patterns such as cream, jelly, foam, suppository and medicine film.Develop safer, the product of practising contraception is the overall goal of family planning contraception research effectively, easily.The family planner in nearly twenty or thirty year of China has made indelible huge contribution for the population control of China.Along with the progress in epoch, the reach of science, a kind of control reproductive tract infection external contraceptive product that has concurrently of the needs in market.Many domestic and international scientific workers have done bigger effort for this reason, have developed some Related products.As domestic " three-in-one " health and happiness safener, multifunctional collyrium for women and " De Erle " multifunctional antiphlogistic contraception health care liquid.The macromolecular material of professor's exploitations such as the external Zaneveld that California university is arranged is used for the development of this series products.In addition, professor Myhling also utilizes a kind of chemical compound as spermicide and anti-infective composition, is engaged in the research of multifunctional product.It's a pity have two problems perplexing our scientist very much: one is that the sperm kill rate is not ideal enough always; Secondly can kill intravaginal normal bacteria, cause dysbacteriosis, and composition is kept away clever different with disappearing of our development.At above problem, the present invention proposes a kind of new technical scheme.
Summary of the invention
The object of the present invention is to provide a kind of control reproductive tract infection external applied contraceptive that has concurrently.
The object of the invention can be achieved through the following technical solutions: union menthylphenoxypolyethoxy ethanol of the present invention, polyketenes iodine, water and polyvinyl alcohol.
On the technique scheme basis, each composition weight percentage is: nonoxynolum 0.1-0.5%, polyketenes iodine 0.2-1.5%, other are an amount of for water and polyvinyl alcohol.
The present invention can be made into suppository.
The present invention has sterilization concurrently and is the suppository of one with contraception, uses one before men and women's sexual life, has not both had sexually transmitted disease (STD) and has propagated, again can be not conceived.Pathogen to reproductive tract infection such as the gonorrhea of spreading wide, mildews has good bactericidal effect especially, and can reach contraceptive effect.
The specific embodiment
'Xiao Biling ' pessary, each composition weight percentage is: nonoxynolum 0.1-0.5%, polyketenes iodine 0.2-1.5%, other are an amount of for water and polyvinyl alcohol.The present invention is a suppository.
Experimental result: product of the present invention 5 minutes is respectively 99.99,99.90,99.98 and 99.96% to gonococcus, escherichia coli, staphylococcus aureus and mycete (Candida albicans) killing rate; It is qualified that the effect of 500mg/L content destroyed hepatitis B virus surface antigen (HBsAg) in 30 minutes; Product of the present invention was killed mankind spermatozoon in 20 seconds 100%, and contraception efficient is up to 99%; This product safety is reliable, does not find reproductive tract local toxicity (as edema, redness etc.), no local absorption performance, no local damage, non-corrosiveness, and not chafe and mucosa, production process does not cause environmental pollution; In addition, product of the present invention is unlikely to cause dysbacteriosis to the rate of hindering of intravaginal normal bacteria lower (killed lactobacillus and have only 56.13% in 15 minutes).
Claims (3)
1, 'Xiao Biling ' pessary, union menthylphenoxypolyethoxy ethanol, polyketenes iodine, water and polyvinyl alcohol are formed.
2, 'Xiao Biling ' pessary is characterised in that: each composition weight percentage is: nonoxynolum 0.1-0.5%, polyketenes iodine 0.2-1.5%, other are an amount of for water and polyvinyl alcohol.
3, 'Xiao Biling ' pessary is characterised in that: be suppository.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02137325 CN1415307A (en) | 2002-10-08 | 2002-10-08 | Xiaobiling vaginal suppository |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 02137325 CN1415307A (en) | 2002-10-08 | 2002-10-08 | Xiaobiling vaginal suppository |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1415307A true CN1415307A (en) | 2003-05-07 |
Family
ID=4748955
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 02137325 Pending CN1415307A (en) | 2002-10-08 | 2002-10-08 | Xiaobiling vaginal suppository |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1415307A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101327187B (en) * | 2007-12-27 | 2010-11-24 | 刘德胜 | Nonoxynol nonylphenoxy-polyethoxyethanol suppositorium and preparation method thereof |
| CN101361707B (en) * | 2008-05-09 | 2012-06-27 | 孙祖越 | Vaginal suppository for exterminating AIDS virus and sperm |
-
2002
- 2002-10-08 CN CN 02137325 patent/CN1415307A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101327187B (en) * | 2007-12-27 | 2010-11-24 | 刘德胜 | Nonoxynol nonylphenoxy-polyethoxyethanol suppositorium and preparation method thereof |
| CN101361707B (en) * | 2008-05-09 | 2012-06-27 | 孙祖越 | Vaginal suppository for exterminating AIDS virus and sperm |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |