CN1412183A - New preparation method of timixatan - Google Patents
New preparation method of timixatan Download PDFInfo
- Publication number
- CN1412183A CN1412183A CN 01131915 CN01131915A CN1412183A CN 1412183 A CN1412183 A CN 1412183A CN 01131915 CN01131915 CN 01131915 CN 01131915 A CN01131915 A CN 01131915A CN 1412183 A CN1412183 A CN 1412183A
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- Prior art keywords
- synthetic method
- telmisartan
- water
- solvent
- hydrolysis
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- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 01131915 CN1204124C (en) | 2001-10-15 | 2001-10-15 | New preparation method of timixatan |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN 01131915 CN1204124C (en) | 2001-10-15 | 2001-10-15 | New preparation method of timixatan |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1412183A true CN1412183A (en) | 2003-04-23 |
CN1204124C CN1204124C (en) | 2005-06-01 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN 01131915 Expired - Fee Related CN1204124C (en) | 2001-10-15 | 2001-10-15 | New preparation method of timixatan |
Country Status (1)
Country | Link |
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CN (1) | CN1204124C (en) |
Cited By (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2006044648A1 (en) * | 2004-10-15 | 2006-04-27 | Teva Pharmaceutical Industries Ltd. | Process for preparing telmisartan |
CN101172968B (en) * | 2006-11-01 | 2010-05-12 | 浙江天宇药业有限公司 | 2-propyl-4 methyl-6-(tolimidazole-2group) benzoglioxaline salt and method for producing the same |
WO2010146187A2 (en) | 2009-06-19 | 2010-12-23 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Process for the preparation of telmisartan |
CN101550107B (en) * | 2009-04-02 | 2011-01-12 | 宁波九胜创新医药科技有限公司 | Method for preparing telmisartan |
EP2277866A1 (en) | 2009-06-22 | 2011-01-26 | Inke, S.A. | Process for preparing telmisartan |
WO2012028925A2 (en) | 2010-09-03 | 2012-03-08 | Ogene Systems (I) Pvt Ltd | An improved process for the preparation of telmisartan |
CN101743228B (en) * | 2007-07-03 | 2014-01-29 | 新梅斯托克尔卡托瓦纳兹德拉韦尔公司 | Process for preparing telmisartan |
US8691999B2 (en) | 2004-05-11 | 2014-04-08 | Cipla Limited | Process for the preparation of telmisartan |
CN105399627A (en) * | 2015-10-22 | 2016-03-16 | 威特(湖南)药业有限公司 | Synthetic method of 4'-bromomethylbiphenyl-2-carboxylate |
CN109912512A (en) * | 2017-12-13 | 2019-06-21 | 上海科胜药物研发有限公司 | A kind of new Telmisartan impurity compound and its preparation method and application |
-
2001
- 2001-10-15 CN CN 01131915 patent/CN1204124C/en not_active Expired - Fee Related
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8691999B2 (en) | 2004-05-11 | 2014-04-08 | Cipla Limited | Process for the preparation of telmisartan |
WO2006044648A1 (en) * | 2004-10-15 | 2006-04-27 | Teva Pharmaceutical Industries Ltd. | Process for preparing telmisartan |
US7501448B2 (en) | 2004-10-15 | 2009-03-10 | Teva Pharmaceutical Industries, Ltd. | Process for preparing telmisartan |
CN101172968B (en) * | 2006-11-01 | 2010-05-12 | 浙江天宇药业有限公司 | 2-propyl-4 methyl-6-(tolimidazole-2group) benzoglioxaline salt and method for producing the same |
CN101743228B (en) * | 2007-07-03 | 2014-01-29 | 新梅斯托克尔卡托瓦纳兹德拉韦尔公司 | Process for preparing telmisartan |
CN101550107B (en) * | 2009-04-02 | 2011-01-12 | 宁波九胜创新医药科技有限公司 | Method for preparing telmisartan |
WO2010146187A2 (en) | 2009-06-19 | 2010-12-23 | Krka, Tovarna Zdravil, D.D., Novo Mesto | Process for the preparation of telmisartan |
EP2277866A1 (en) | 2009-06-22 | 2011-01-26 | Inke, S.A. | Process for preparing telmisartan |
WO2012028925A2 (en) | 2010-09-03 | 2012-03-08 | Ogene Systems (I) Pvt Ltd | An improved process for the preparation of telmisartan |
CN105399627A (en) * | 2015-10-22 | 2016-03-16 | 威特(湖南)药业有限公司 | Synthetic method of 4'-bromomethylbiphenyl-2-carboxylate |
CN109912512A (en) * | 2017-12-13 | 2019-06-21 | 上海科胜药物研发有限公司 | A kind of new Telmisartan impurity compound and its preparation method and application |
CN109912512B (en) * | 2017-12-13 | 2023-05-30 | 上海科胜药物研发有限公司 | New telmisartan impurity compound and preparation method and application thereof |
Also Published As
Publication number | Publication date |
---|---|
CN1204124C (en) | 2005-06-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C41 | Transfer of patent application or patent right or utility model | ||
C56 | Change in the name or address of the patentee | ||
CP03 | Change of name, title or address |
Address after: 294 Taiyuan Road, Shanghai, zip code: 200031 Co-patentee after: TOPHARMAN SHANGHAI Co.,Ltd. Patentee after: SHANGHAI INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF SCIENCES Address before: 294 Taiyuan Road, Shanghai, zip code: 200031 Co-patentee before: Shanghai Tehua Pharmaceutical and Chemical Co.,Ltd. Patentee before: Shanghai Institute of Materia Medica, Chinese Academy of Sciences |
|
TR01 | Transfer of patent right |
Effective date of registration: 20081212 Address after: The German Ingelheim 55216 accusative Street No. 173 Patentee after: BOEHRINGER INGELHEIM INTERNATIONAL GmbH Address before: 294 Taiyuan Road, Shanghai, zip code: 200031 Co-patentee before: TOPHARMAN SHANGHAI Co.,Ltd. Patentee before: Shanghai Institute of Materia Medica, Chinese Academy of Sciences |
|
ASS | Succession or assignment of patent right |
Owner name: BOEHRINGER INGELHEIM INTERNATIONAL CO., LTD. Free format text: FORMER OWNER: SHANGHAI PHARMACEUTICAL INST., CHINESE ACADEMY OF SCIENCES Effective date: 20081212 |
|
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20050601 Termination date: 20131015 |