CN1406481A

CN1406481A - Micro-emulsion composition containing bromine pestcide and monuron and preparation thereof

Info

Publication number: CN1406481A
Application number: CN 01128580
Authority: CN
Inventors: 王跃龙; 王霖; 曹永松; 梁骥; 陈九星
Original assignee: Hunan Research Institute of Chemical Industry
Current assignee: Hunan Research Institute of Chemical Industry
Priority date: 2001-09-06
Filing date: 2001-09-06
Publication date: 2003-04-02
Anticipated expiration: 2021-09-06
Also published as: CN1232170C

Abstract

A composite microemulsion as insecticide is prepared from bromothalonil or bromothalonil plus monosultap, cosolvent, deionized water, surfactant, defoaming agent, and anti-freezing agent. Its advantages are broad spectrum, high safety and no environmental pollution.

Description

Contain micro-emulsion composition of insecticide chlorfenapyr or chlorfenapyr+desinsection list and preparation method thereof

The present invention relates to microemulsion that a kind of micro-emulsion composition that contains insecticide chlorfenapyr or chlorfenapyr+desinsection list and preparation method thereof, particularly chlorfenapyr or chlorfenapyr+desinsection list and cosolvent, deionized water, surfactant, defoamer, antifreeze be mixed with and preparation method thereof.

People know, chlorfenapyr: chemical name is 4-bromo-2-rubigan-1-ethoxyl methyl-5-trifluoromethyl pyrpole-3-nitrile, and structural formula is: Outward appearance is a faint yellow solid, it is a kind of Insecticidal and acaricidal agent of efficient, low toxicity, be widely used in various pests and mite class on the crops such as control paddy rice, vegetables, cotton, fruit tree, soybean, as the snout moth's larva of rice, tetranychid, leafhopper, purplish red short hairs mite, colorado potato beetles, noctuid, diamond-back moth, cabbage caterpillar, cotton bollworm, aphid, mythimna separata, miller, caterpillar, leaf moth, codling moth, heart-eating worm, grape borer etc., the just harm of controlled various pests of a dispenser, and, can not produce poisoning to crop safety.American Cyanamid Company has applied for patent (patent No. 88106516.1) on July 28th, 1988 in China, this patent disclosure this compound and some compositions, but do not relate to microemulsion.

The desinsection list: chemical name is 2-N, N dimethylamine base-1-sodium thiosulfate base-3-propane thiosulfate, and structural formula is: , be China's a kind of pesticide species of innovation and creation voluntarily.It is a kind of broad spectrum pesticide, insect had strong stomach toxicity, tag and systemic action, and have concurrently stifling, ovicidal action, be widely used in the control paddy rice, corn, vegetables, fruit tree, the tea soybean, the multiple lepidoptera pest of crops such as sugarcane, to the rice grub pink rice borer, striped rice borer, paddy stem borer, leaf-roller, rice plant skipper, thrips, leafhopper, mythimna separata, scotellaris, plant hopper, the vegetable-crop pest-insect cabbage caterpillar, Oeobia undalis, striped flea-beetle, silver mosquito noctuid, dish leaf insect, the dish caterpillar, educate stinkbug, jassids, tie leaf miner mutually, tens kinds of insects such as rust wall wind have excellent control efficiency, secondly oncomelania and ovum are had special efficacy.The desinsection list has been developed many preparations, but the report with the chlorfenapyr complex preparation is seen at the end.

The purpose of this invention is to provide a kind of micro-emulsion composition that contains insecticide chlorfenapyr or chlorfenapyr+desinsection list.

Composition of the present invention is: chlorfenapyr or chlorfenapyr+desinsection list is active ingredient 1%～50% (w/w), surfactant 6%～15% (w/w), cosolvent 3%～7% (w/w), deionized water 21%～87% (w/w), defoamer 1%～2% (w/w), antifreeze 2%～5% (w/w).Active ingredient among the present invention is chlorfenapyr or chlorfenapyr+desinsection list; The surfactant that uses among the present invention is anionic, nonionic or their mixed type, and DBSA base salt, lauryl sulfate, lignosulfonates NNO, BX, alkyl polyoxyethylene ether phosphate, No. 500, farming breast, agricultural emulsifier NO, No. 100, peaceful breast, NP-10, NP-15, NP-20, BY140, No. 1600, No. 1601, No. 1602, tween, sorbitol polyoxyethylene ether, 0204,0206B etc. are arranged; The selected cosolvent of the present invention is aromatic hydrocarbon, heavy aromatic hydrocarbon, fatty alcohol, and preferred cosolvent is cyclohexanone, dimethyl formamide, acetone, dimethyl sulfoxide (DMSO), ethyl acetate, oxolane, dimethylbenzene etc.; The selected continuous phase of the present invention is deionized water; The selected defoamer of the present invention is n-butanol, n-octyl alcohol, dimethyl-silicon wet goods; The selected optional spent glycol of antifreeze of the present invention, propane diols, glycerine, polyethylene glycol, urea etc.

Preparation method of the present invention is: earlier with chlorfenapyr or the former medicinal cosolvent dissolving of chlorfenapyr+desinsection list, add surfactant then, add the stronger surfactant of hydrophily earlier, add the stronger surfactant of lipophile after stirring again, stir, add defoamer again, stir the oil phase that forms homogeneous, deionized water is added in the above-mentioned oil phase, the limit edged stirs again, and adds antifreeze at last and stirs and form homogeneous, transparent, stable microemulsion agent; The selected mixing speed of the present invention is 60 to change part clock～1700 rev/min, and mixing time is 30 minutes～2 hours, and whipping temp is a normal temperature.

The present invention is mainly used in various pests and mite class on the crops such as paddy rice, vegetables, cotton, fruit tree, soybean, as the snout moth's larva of rice, tetranychid, leafhopper, purplish red short hairs mite, colorado potato beetles, noctuid, diamond-back moth, cabbage caterpillar, cotton bollworm, aphid, mythimna separata, miller, caterpillar, leaf moth, codling moth, heart-eating worm, grape borer etc., the just harm of controlled various pests of a dispenser, and, can not produce poisoning to crop safety.The present invention is owing to being to be continuous phase with the deionized water, and is with low cost, can reduce drug cost.In addition, cosolvent content of the present invention is low, has reduced environmental pollution, belongs to environment-friendly type novel pesticide preparation.

The invention will be further described below in conjunction with embodiment and test of pesticide effectiveness example:

Embodiment 1-3

Chlorfenapyr, cosolvent, water, surfactant, defoamer, antifreeze etc. are mixed with microemulsion, and it is as follows to fill a prescription:

Table 1 Embodiment 4-6

Table 2

Embodiment 7-9

Chlorfenapyr+desinsection list (being designated hereinafter simply as bromine kills), cosolvent, water, surfactant, defoamer, antifreeze etc. are mixed with microemulsion, and it is as follows to fill a prescription:

Table 3

Test example 1:

Giving birth to the survey indoor bioassay result of portion through national agricultural chemicals initiative base, Hunan, center shows, 5% chlorfenapyr microemulsion and 15% bromine kill microemulsion leafhopper, diamond-back moth, cabbage caterpillar, cotton bollworm, aphid, mythimna separata etc. are had good biologically active, and it the results are shown in following table.

Table 4

Test example 2～4:

With cabbage caterpillar and the diamond-back moth on the 5% chlorfenapyr microemulsion control wild cabbage, with 10% chlorfenapyr suspending agent is contrast, and 15% bromine is killed the microemulsion control snout moth's larva of rice, and killing wetting powder with 15 bromines is contrast, through field plot trial, find that control efficiency all is better than contrasting medicine.It the results are shown in following table:

Table 5

	Test example 2		Test example 3		Test example 4
	Test example 2		Test example 3		Test example 4		Investigational agent	The contrast medicine	Investigational agent	The contrast medicine	Investigational agent	The contrast medicine
	5% chlorfenapyr microemulsion	10% chlorfenapyr suspending agent	5% chlorfenapyr microemulsion	10% chlorfenapyr suspending agent	15% bromine kills microemulsion	15% bromine kills wetting powder	Investigational agent	The contrast medicine	Investigational agent	The contrast medicine	Investigational agent	The contrast medicine
	5% chlorfenapyr microemulsion	10% chlorfenapyr suspending agent	5% chlorfenapyr microemulsion	10% chlorfenapyr suspending agent	15% bromine kills microemulsion	15% bromine kills wetting powder	Pest control	The wild cabbage diamond-back moth	The wild cabbage diamond-back moth	Cabbage pieris	Cabbage pieris	The snout moth's larva of rice	The snout moth's larva of rice
Every mu of consumption	40～50ml/ mu	20～25ml/ mu	40～50ml/ mu	20～25ml/ mu	35～45ml/ mu	35～45g/ mu	Pest control	The wild cabbage diamond-back moth	The wild cabbage diamond-back moth	Cabbage pieris	Cabbage pieris	The snout moth's larva of rice	The snout moth's larva of rice
Every mu of consumption	40～50ml/ mu	20～25ml/ mu	40～50ml/ mu	20～25ml/ mu	35～45ml/ mu	35～45g/ mu	Preventive effect	More than 97%	Below 85%	More than 98%	Below 85%	More than 96%	Below 75%
The longevity of residure	2 months		2 months		2 months		Preventive effect	More than 97%	Below 85%	More than 98%	Below 85%	More than 96%	Below 75%

Claims

1, a kind of micro-emulsion composition that contains insecticide chlorfenapyr or chlorfenapyr+desinsection list, it is composed as follows: active ingredient chlorfenapyr or chlorfenapyr+desinsection list is 1%～50% (w/w), surfactant is 6%～15% (w/w), cosolvent is 3%～7% (w/w), deionized water is 21%～87% (w/w), defoamer is 1%～2% (w/w), and antifreeze is 2%～5% (w/w).

2, according to the described a kind of proportioning that contains the micro-emulsion composition active ingredient of bromothalonil and monosultap of claim 1 be: chlorfenapyr: desinsection list=0.2～20: 10～40 (weight ratios).

3, according to the described a kind of micro-emulsion composition that contains insecticide chlorfenapyr or chlorfenapyr+desinsection list of claim 1, it is characterized in that employed surfactant can be an anionic, nonionic or their mixed type, preferred surfactants have DBSA base salt, lauryl sulfate, lignosulfonates NNO, BX, alkyl polyoxyethylene ether phosphate, No. 500, farming breast, agricultural emulsifier NO, No. 100, peaceful breast, NP-10, NP-15, NP-20, BY140, No. 1600, No. 1601, No. 1602, tween, sorbitol polyoxyethylene ether, 0204C, 0206B etc.; Used cosolvent is aromatic hydrocarbon, heavy aromatic hydrocarbon, fatty alcohol, and preferred cosolvent is cyclohexanone, dimethyl formamide, acetone, dimethylbenzene, dimethyl sulfoxide (DMSO), ethyl acetate, oxolane, phenmethylol etc.; Used continuous phase is deionized water; Used defoamer is n-butanol, n-octyl alcohol, dimethyl-silicon wet goods; Used antifreeze is ethylene glycol, propane diols, glycerine, polyethylene glycol, aromatic hydrocarbon, heavy aromatic hydrocarbon etc.

4, a kind of preparation method who contains the micro-emulsion composition of insecticide chlorfenapyr or chlorfenapyr+desinsection list according to claim 1, it is characterized in that: earlier with chlorfenapyr or the former medicinal cosolvent dissolving of chlorfenapyr+desinsection list, add surfactant then, add the stronger surfactant of hydrophily earlier, add the stronger surfactant of lipophile after stirring again, stir, add defoamer again, stir the oil phase that forms homogeneous, deionized water is added in the above-mentioned oil phase again, the limit edged stirs, and adds the antifreeze formation homogeneous that stirs at last, transparent, the stable microemulsion agent; The selected mixing speed of the present invention is 60 to change part clock～1700 rev/min, and mixing time is 30 minutes～2 hours, and whipping temp is a normal temperature.