CN1391901A - Injection for curing hemangioma - Google Patents
Injection for curing hemangioma Download PDFInfo
- Publication number
- CN1391901A CN1391901A CN 01115049 CN01115049A CN1391901A CN 1391901 A CN1391901 A CN 1391901A CN 01115049 CN01115049 CN 01115049 CN 01115049 A CN01115049 A CN 01115049A CN 1391901 A CN1391901 A CN 1391901A
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- China
- Prior art keywords
- injection
- hemangioma
- angiomatous
- dexamethasone
- bleomycin
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The injection for treating hemangioma consists of Pingyangmycin, 0.5% concentration lidocaine and dexamethasone. It has satisfactory treating effect in treating various hemangioma, including strawberry-like hemangioma, cavernous hemangioma, mixed hemangioma, capillary hemangioma, etc.
Description
The invention belongs to pharmaceutical, particularly be angiomatous active drug--treat angiomatous injection.
Congenital hemangioma is more common in infant.Common have a strawberry hemangioma; Mixed type hemangioma; Cavernous hemangioma.Often betide face, extremity, trunk etc. are located, occasionally in internal organs.Can cause bleeding and be suffered from the dysfunction of organ pipe, Therapeutic Method often is principle with the security function, in conjunction with concrete condition, adopt liquid nitrogen or methods such as carbon dioxide is freezing, injection of sclerosing agent, isotope irradiation or operation, the weak curative effect that has easily recurs, advanced hemangioma therapy apparatus expense costliness, patient and his family are difficult to bear.The prescription of treatment by Chinese herbs blood circulation promoting and blood stasis dispelling commonly used, but curative effect is not ideal.The Bleomycin A5 injection is effective in cure to the treatment hemangioma, but easily cause hyperpyrexia, gastrointestinal reaction, dermoreaction (pigmentation, keratinization thicken, dermatitis, erythra etc.), alopecia, acra fiber crops are painful, stomatitis, the pneumonia sample becomes or pulmonary fibrosis etc., and especially children's's nervus centralis is grown unsoundly, easily causes tic, tracheospasm, dyspnea, blood pressure reduces, confusion, untimelyly easily meet accident if rescue, thus careful always be used for clinical.
The objective of the invention is to mix other drug on the basis of Bleomycin A5, a kind of compound preparation that provides can be treated angiomatous injection safely, effectively.
The object of the present invention is achieved like this, and concrete scheme is described as follows:
The angiomatous injection of a kind of treatment, it is the injection of being made by the following weight proportion raw material:
The better scope optimum range of material name effective range
Bleomycin A5 3-10mg 3-7mg 4-5mg
0.5% lignocaine 3-10ml 4-8ml 5-7ml
Dexamethasone 1-5mg 2-4mg 3-4mg
The angiomatous injection of above-mentioned treatment is to be weighed up according to weight proportion by above-mentioned three kinds of raw materials, adds an amount of normal saline dilution, mix homogeneously again, promptly gets standby.
The angiomatous injection of above-mentioned treatment raw material is by weight ratio formed embodiment:
Example 1, Bleomycin A5 3mg, 0.5% lignocaine 3ml, dexamethasone 1mg.
Example 2, Bleomycin A5 4mg, 0.5% lignocaine 5ml, dexamethasone 2mg.
Example 3, Bleomycin A5 5mg, 0.5% lignocaine 8ml, dexamethasone 3mg.
Therapeutic Method: use above-mentioned preparation, look tumor body size and suck basilar part and the tumor body wellability injection of medicinal liquid in pathological changes, concrete injected dose also will take the circumstances into consideration to use according to patient's the year order and the size of diseased region and tumor body.Injection in general 7-10 days is once promptly healed for 1-4 time, seldom above 5 times.
It is satisfactory for result that the present invention treats angiomatous injection, safe and effective, do not have recurrence, makes us very satisfied, and dexamethasone can resist adverse side effects such as the fever, allergy, anorexia of Bleomycin A5, and collaborative its curative effect is arranged; Utilize the direct molten medicine injection of 0.5% lignocaine, deducted the misery of crude drug after the first local anaesthesia, remove from because of making the pain of skin test as local anaesthesia with lignocaine simultaneously.The checking of example surplus clinical 200, use this medicine to avoid causing bad side effect such as heating, guaranteed the safety of medication, exempted patient's misery, good especially to body surface hemangioma curative effect, successively treat strawberry hemangioma 92 examples, cavernous hemangioma 68 examples, mixed type hemangioma 36 examples are not seen recurrence so far.Can cure capillary hemangioma, cavernous hemangioma, mixed type hemangioma, hemangioma racemosum, portwine stain are had certain inhibitory action, also effective to other carcinoma at body surface position, as a breast carcinoma, survived after treating 5 times 7 years, a potential head tumor colli disappears through treatment.
Model case: example 1, the week certain, the man, 57 years old, because of pulmonary carcinoma is admitted to hospital, head is seen the tumor of one 14 * 3 * 3.5cm, cuts evacuation of pus through local hospital, is diagnosed as squamous cell carcinoma, obstinate, stench is unpleasant, through this liquid of local injection 3ml, and the tumor spontaneous recovery that disappears next day, recurrence again.
Example 2, Chen, the man, 65 years old, because of pulmonary carcinoma is admitted to hospital, there was subcutaneous metastasis 7 * a 6 * 2cm at the back, and the previous night is with we treatment, and inferior morning, pain and pressure symptom disappeared, and tumor site and normal skin are as good as.
Example 3 finishes so-and-so, the woman, and 65 years old, left side breast carcinoma, lump 3 * 4cm because of financial difficulties, can not perform the operation, and flows out stench liquid throughout the year, and through this law treatment, 6 years so far are still alive.
Example 4, Ma, the woman, 26 years old, crown occipitalia had the 3 places thing that swells, and is respectively 7 * 6 * 1cm; 3 * 2 * 1cm; 2 * 1 * 1cm, the surface is uneven, and color is scarlet, is diagnosed as head sweat gland sample nevus, and through this law treatment 6 times, swollen thing disappears, not mark.
In addition, to injecting in the neoplasm metastasis lymph node, curative effect is also good, play dwindle, disappearance and dormant effect.
Claims (4)
1, the angiomatous injection of a kind of treatment is characterized in that it is the injection of being made by the following weight proportion raw material:
Bleomycin A5 3-10mg, 0.5% lignocaine 3-10ml, dexamethasone 1-5mg;
Above-mentioned 3 kinds of raw materials are mixed in proportion.
2, the angiomatous injection of treatment according to claim 1 is characterized in that it is the injection of being made by the following weight proportion raw material:
Bleomycin A5 3-7mg, 0.5% lignocaine 4-8ml, dexamethasone 2-4mg.
3, the angiomatous injection of treatment according to claim 1 is characterized in that it is the injection of being made by the following weight proportion raw material:
Bleomycin A5 4-5mg, 0.5% lignocaine 5-7ml, dexamethasone 3-4mg.
4, the angiomatous injection of treatment according to claim 1 is characterized in that it is the injection of being made by the following weight proportion raw material:
Bleomycin A5 4mg, 0.5% lignocaine 5ml, dexamethasone 2mg.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01115049 CN1391901A (en) | 2001-06-18 | 2001-06-18 | Injection for curing hemangioma |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 01115049 CN1391901A (en) | 2001-06-18 | 2001-06-18 | Injection for curing hemangioma |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1391901A true CN1391901A (en) | 2003-01-22 |
Family
ID=4661640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 01115049 Pending CN1391901A (en) | 2001-06-18 | 2001-06-18 | Injection for curing hemangioma |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1391901A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103889416A (en) * | 2011-10-19 | 2014-06-25 | 高德美国际公司 | Method for treating capillary hemangiomas |
| US10206972B2 (en) | 2014-04-03 | 2019-02-19 | Guangzhou Yidai Pharmaceutical Co., Ltd. | Anti-vascular disease and antitumor pharmaceutical composition and use thereof |
-
2001
- 2001-06-18 CN CN 01115049 patent/CN1391901A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103889416A (en) * | 2011-10-19 | 2014-06-25 | 高德美国际公司 | Method for treating capillary hemangiomas |
| US10206972B2 (en) | 2014-04-03 | 2019-02-19 | Guangzhou Yidai Pharmaceutical Co., Ltd. | Anti-vascular disease and antitumor pharmaceutical composition and use thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C57 | Notification of unclear or unknown address | ||
| DD01 | Delivery of document by public notice |
Addressee: Zhao Peiling Document name: Notice of publication of application for patent for invention |
|
| C57 | Notification of unclear or unknown address | ||
| DD01 | Delivery of document by public notice |
Addressee: Zhao Peiling Document name: Notification before expiration of term |
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| C57 | Notification of unclear or unknown address | ||
| DD01 | Delivery of document by public notice |
Addressee: Zhao Peiling Document name: Deemed as a notice of withdrawal |
|
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |