CN1390123A - 使用iNOS抑制剂治疗或预防近视眼 - Google Patents

使用iNOS抑制剂治疗或预防近视眼 Download PDF

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Publication number
CN1390123A
CN1390123A CN00815736.7A CN00815736A CN1390123A CN 1390123 A CN1390123 A CN 1390123A CN 00815736 A CN00815736 A CN 00815736A CN 1390123 A CN1390123 A CN 1390123A
Authority
CN
China
Prior art keywords
myopia
prevention
compound
treatment
treating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN00815736.7A
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English (en)
Inventor
邱春亿
郑天香
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
YONGGUANG PHARMACEUTICAL CO Ltd
Original Assignee
YONGGUANG PHARMACEUTICAL CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by YONGGUANG PHARMACEUTICAL CO Ltd filed Critical YONGGUANG PHARMACEUTICAL CO Ltd
Publication of CN1390123A publication Critical patent/CN1390123A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/513—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim having oxo groups directly attached to the heterocyclic ring, e.g. cytosine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

本发明涉及通式(I)(其中,R1表示氢,任选取代的C1－C6烷基等;m表示0－2的整数,n表示0－5的整数;A表示5－10元含有1－4个选自N、O和S的相同或相异原子的单环或多环杂环,或碳环;B表示芳环;)表示的肼衍生物,其制备方法,含有其作为有效成分的药物组合物,以及其在制备用于治疗或预防近视眼的药物中的应用和近视眼的预防和治疗方法,和一种含有其和相关说明资料的商业药盒。本发明的化合物具有有效的预防或治疗近视眼的效果。

Description

PCT国内申请，说明书已公开。

Claims (1)

  1. PCT国内申请，权利要求书已公开。
CN00815736.7A 2000-09-20 2000-09-20 使用iNOS抑制剂治疗或预防近视眼 Pending CN1390123A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/CN2000/000285 WO2002024188A1 (fr) 2000-09-20 2000-09-20 Inhibiteur de la no synthetase inductible (inos) utilise pour le traitement ou la prevention de la myopie

Publications (1)

Publication Number Publication Date
CN1390123A true CN1390123A (zh) 2003-01-08

Family

ID=4574702

Family Applications (1)

Application Number Title Priority Date Filing Date
CN00815736.7A Pending CN1390123A (zh) 2000-09-20 2000-09-20 使用iNOS抑制剂治疗或预防近视眼

Country Status (3)

Country Link
CN (1) CN1390123A (zh)
AU (1) AU2000275034A1 (zh)
WO (1) WO2002024188A1 (zh)

Also Published As

Publication number Publication date
AU2000275034A1 (en) 2002-04-02
WO2002024188A1 (fr) 2002-03-28

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Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
C02 Deemed withdrawal of patent application after publication (patent law 2001)
WD01 Invention patent application deemed withdrawn after publication