CN1361418A - Digital nuclear magnetic resonance control console - Google Patents
Digital nuclear magnetic resonance control console Download PDFInfo
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- CN1361418A CN1361418A CN 00128170 CN00128170A CN1361418A CN 1361418 A CN1361418 A CN 1361418A CN 00128170 CN00128170 CN 00128170 CN 00128170 A CN00128170 A CN 00128170A CN 1361418 A CN1361418 A CN 1361418A
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Abstract
The digital nuclear magnetic resonance control console consists of pulse programmed controller, RF passage and sampling system as main parts. The bus type control makes it possible to set the control module in any position of system bus backboard, to poll the additional module flag and its type automatically. Mid frequency direct sampling technology of multiple mode variable frequency is used. The present invention is suitable for nuclear magnetic resonance imaging instrument and nuclear magnetic resonance spectrometer and may be directly used in high-field structure nuclear magnetic resonance instrument.
Description
The present invention relates to the nuclear magnetic resonance field, relate in particular to the Digital Control table apparatus of NMR imaging instrument and nuclear magnetic resonance spectrometer.
Before the nineties, what adopted the radio-frequency channel of nuclear magnetic resonance control console is Analogical Circuit Technique, the adjustment precision of radiofrequency signal amplitude, frequency and phase place is limited, switch speed is slower, can not satisfy the demand that the special-shaped radio-frequency pulse switches and accurately adjusts for the high speed of amplitude, frequency and phase place in the modern nuclear magnetic resonance experiment.
Adopt two companies that the U.S. and Britain are arranged of digital nuclear magnetic resonance control desk technical scheme at present.The scheme that the Apollo/LF product (1998) that U.S. Tecmag company produces adopts is: total system has adopted the master-slave mode PPG programme pulse generator based on multi-digital signal processor (DSP); Transmitter has used frequency and the continuously adjustable Direct Digital Frequency Synthesizers of phase place; Receiver section is mainly high speed analog/digital converter (14bit/10MHz) and special digital quadrature frequency conversion and decimation filter of digital.There is following defective in this product: 1, owing to the connection between the principal and subordinate's module in the reason PPG programme pulse generator of system design can only be adopted the wire jumper mode, have a strong impact on the reliability of system; 2, each module must be placed on the assigned address of system, influences the extensibility of system; 3, DDS reference frequency lower (50MHz) in the transmitter can't directly be applied in the instrument of High-Field (high workload frequency); Though 4 systems have adopted the if direct sampling technology, the IF-FRE of system and sample frequency are still lower, are respectively 12.5MHz and 10MHz.These factors have determined system can only be operated in the lower frequency ranges, can't satisfy the demand of High-Field, high resolution NMR instrument system.
Another kind is the MARAN DRX product that Britain Resonance Instrument company produces.This product is except having the defective that goes up a kind of scheme, and also exist following point: one is that radio-frequency transmissions and receiving unit are placed in the unit, exists the phase mutual interference owing to transmit and receive between part, has influenced the signal to noise ratio (S/N ratio) of system; Another is only to need the multipath reception passage in the array imaging system, but this product can only provide multichannel emission and multipath reception passage simultaneously, has caused the waste of hardware resource.
The purpose of this invention is to provide a kind of digital nuclear magnetic resonance control console, this device is applicable to NMR imaging instrument and nuclear magnetic resonance spectrometer, and is easy to use, reliability is high, extensibility is strong, can directly apply to the nuclear magnetic resonance apparatus of High-Field.
In order to achieve the above object, the present invention adopts following technical scheme:
Digital nuclear magnetic resonance control console is mainly by principal computer, control and data interface module, system bus backboard, main pulse program controling module, form from pulse protocol control module, gradient control module, satellite interface, transmitter, receiver, gradient-driven and master clock signal generator.The main pulse program controling module adopts bus type to the control from pulse protocol control module and gradient control module, promptly uses identical control signal wire, makes them can be placed on the optional position of system bus backboard; The main pulse program controling module, the sign of add-on modules such as satellite interface, transmitter, receiver and gradient-driven can be inquired about automatically, the type of add-on module can be detected automatically from pulse protocol control and gradient control module; Used the if direct sampling technology of multi-mode variable sampling frequency; High speed Analog-to-Digital Conversion Technology, orthogonal digital down-conversion technique, digital decimation filtering technique, high-speed digital signal treatment technology and orthogonal radio frequency transmitter techniques have been used simultaneously.
With the main pulse program controling module, be connected with principal computer by the system bus backboard by the system control interface module with gradient modules, can realize the high-speed real-time transmission of program and data from the pulse protocol control module.
Main pulse program controling module and 1～30 constitute pulse programming controller from pulse protocol control module and gradient control module, and each module has wherein all been given an address number.Control desk device of the present invention is the automatic checkout system configuration when each the startup, principal computer to main pulse program controling module and 1～30 from pulse protocol control module and gradient control module loading procedure, make their position to change arbitrarily, simplify the debugging of system, made things convenient for the upgrading of system.Radio-frequency channel and other modules adopt the mode of submodule to be attached on pulse protocol control module or the gradient control module by pulse protocol control module or the control of gradient control module.So both designs of simplified system bus backplane help mass production again.
Pulse programming controller can have different configurations.Minimum is configured to: the control desk device uses main pulse program controling module control data acquisition system, and one from pulse protocol control module control radio-frequency pulse (comprising rf frequency, amplitude, phase place and burst length etc.).A nuclear magnetic resonance control console with single transmit and receiving cable has been formed in this configuration, can satisfy the demand (as pulsed nuclear magnetic resonance oilseed oleaginousness analyser) of low-cost instrument.Change the main pulse program controling module into control satellite interface module (as holding circuit), add another, add the gradient pulse control module, can satisfy the demand of conventional NMR imaging instrument from pulse protocol control module control data acquisition system.Native system can be selected 1～30 for use from the pulse protocol module, therefore, emission and/or receiving cable number, satellite interface module how much have a very strong scalability.
The control desk device also comprises rf transmitter unit, radio-frequency transmitter unit, gradient fields unit and security monitoring parts.The reference frequency of the direct synthetic technology of the numerical frequency in the rf transmitter unit (DDS) is 200～300MHz, can produce up to the radiofrequency signal of 80MHz directly to use for High-Field imaging instrument.To being lower than the radiofrequency signal of 40MHz, transmission channel can produce the two paths of signals of quadrature, can directly be exported after filtering by the signal of DDS, is specially adapted to use the NMR imaging instrument device of the dull and stereotyped transmitting coil of open quadrature.When the instrument frequency of operation required to be higher than 80MHz, DDS can produce the radiofrequency signal of 80～500MHz with the frequency synthesizer mixing, but radiofrequency signal has all characteristics of flexible of high stable, low noise, amplitude, phase place and frequency.
Receiver unit adopts the many sample frequency of multi-mode to penetrate/if direct sampling, digital quadrature detection (orthogonal digital down coversion) and digital decimation filtering technique.When frequency of operation is 100kHz～80MHz, use multi-frequency radio frequency Direct Sampling, sample frequency is up to per second and samples 65,000,000 times (65MSPS), uses different sample frequency for different working frequency range, and the assurance system is adjustable continuously from the frequency of operation in 100kHz～80MHz scope.When frequency of operation is higher than 80MHz, convert the signal into Direct Sampling on the intermediate frequency of 37.5MHz through mixing.Digital signal after the sampling is carried out digital quadrature detection and filtering extraction (adopting special-purpose programmable chip) through the orthogonal digital lower frequency changer circuit.Filtered data are sent to the system bus backboard by pulse programming controller, and after the system control interface module arrives principal computer.
The gradient pulse control module has functions such as digital eddy current compensation, is directly inputted to the gradient power amplifier after the digital analog converter conversion of its output by the gradient unit.
The satellite interface module contains the programmable logic array chip, and the user can be according to the needs setting of oneself.
System controlling software can run on several operation systems such as WindowsNT/98/2000 or Linux based on the ActiveX technology of Microsoft.
In sum, the present invention has height scalability, wide operating frequency range, the high digital nuclear magnetic resonance control console that receives bandwidth.This device can be used for High-Field high resolution NMR spectra instrument, nuclear magnetic resonance image-forming apparatus and multiple nuclear magnetic resonance dedicated analysis instrument.
Compared with prior art, the present invention has following advantage:
1, have very wide operating frequency range, can be in the frequency range work of 100KHz-500MHz.
2, multimode, principal and subordinate's parallel type, extendible pulse programming controller flexibly, the conversion arbitrarily of the position of each pulse protocol control module is used simple, easy to operate.
3, each module of control desk device of the present invention is relatively independent, can be upgraded to higher performance separately, for the upgrading of system provides convenience.
4, the present invention has very strong scalability, can be applied in the NMR system of plurality of specifications: as nuclear magnetic resonance oilseed analyser, nuclear magnetic resonance core analysis instrument, nuclear magnetic resonance image-forming apparatus and nuclear magnetic resonance spectrometer etc.
5, the present invention has plug-and-play feature, and the automatic detection module of energy also uses corresponding driving.
Fig. 1 is the digital nuclear magnetic resonance control console block diagram.
The present invention is further illustrated below in conjunction with accompanying drawing.
The present invention is mainly by principal computer, control and data interface module, system bus backboard, main pulse program controling module, form from pulse protocol control module, gradient control module, satellite interface, transmitter, receiver, gradient-driven and major clock module.
Principal computer is delivered to control and data interface module with steering order and data by built-in interface card and stube cable, and receives data and status information.
Control comprises system interface, digital signal processor and control and data-interface with data interface module.It at first transmits next instruction and data buffer-stored to principal computer in the storer of digital signal processor, after format conversion, delivers on corresponding pulse protocol or the gradient control module through the system bus backboard; Simultaneously, it also receives the data that these modules transmit by the system bus backboard, passes back to principal computer then.
The main pulse program controling module, have identical structure from the pulse protocol control module with the gradient control module, it comprises programmable logic controller (PLC), digital signal processor and serial ports, expansion interface, impact damper several sections.The programmable logic controller (PLC) major function is the bidirectional buffering with the Signals ﹠ Systems bus backplane signal of the signal interpretation of system bus backboard and digital signal processor.The main pulse program module is also finished by it the control of other pulse protocol modules and gradient control module.Serial ports, expansion interface and impact damper are mainly realized the data that digital signal processor is passed back the control and the reception external unit of external unit.
Satellite interface comprises programmable logic array interface and level converting section, and its function is to produce the low speed control signal and receives external status signals.
Outer synchronous signal then is used to make the operation of The whole control table apparatus and external signal (after one's own heart electric switch control signal) synchronous.
Transmitter comprises programmable logic array chip interface, Direct Digital Frequency Synthesizers and wave filter.The programmable logic array chip interface is used to control and read the state of Direct Digital Frequency Synthesizers.Pulse programming controller is also directly controlled the switch of Direct Digital Frequency Synthesizers and is produced the noise gate-control signal of other peripheral hardwares of control.Direct Digital Frequency Synthesizers produces all adjustable quadrature radio-frequency signals of frequency, phase place and amplitude and exports through behind the filter filtering.
Receiver comprises programmable logic array interface, digital quadrature frequency conversion and decimation filter and analog-digital converter.The simulating signal of being come by the nuclear magnetic resonance receiving system at first is converted to digital signal by analog/digital converter, again by sending pulse programming controller back to by the programmable logic array interface after digital quadrature frequency conversion and the decimation filter conversion.The latter is also by the quadrature frequency conversion of programmable logic array interface control figure and decimation filter and analog/digital converter, and direct control figure quadrature frequency conversion and decimation filter switch, produces the noise gate-control signal of other peripheral hardwares of control.
Gradient-driven comprises the digital/analog converter of photoisolator and 3 20-24 positions.Photoisolator is used to transmit the gradient control module to digital analog converter, and being electrically connected of two isolated parts.Digital analog converter is converted to digital signal the gradient control signal of simulation.The switch of gradient gate control gradient power amplifier.
Deliver to the each several part of system behind the buffer clock signal that the master clock signal generator produces.
Embodiment 1
The minimum system pattern
Under minimal mode, system comprises: principal computer, control and data interface module master clock generator module, system bus backboard, transmitter module receiver module and two pulse protocol control modules: main pulse program controling module and one are from the pulse protocol control module.
Principal computer is delivered to control and data interface module with steering order and data by interface card and stube cable.Control at first is buffered in the instruction and data that the principal computer transmission comes in the storer of digital signal processor with data interface module, delivers on the corresponding pulse protocol control module through the system bus backboard through after certain format conversion; Simultaneously, it also receives the data that these modules transmit by the system bus backboard, passes back to principal computer then.Main pulse program module receiver control module controls transmitter module from the pulse protocol control module.This minimal configuration has been formed a nuclear magnetic resonance control console with single transmit and receiving cable, can satisfy the demand (as pulsed nuclear magnetic resonance oilseed oleaginousness analyser) of low-cost instrument.Deliver to the each several part of system behind the buffer clock signal that the master clock signal generator produces.
Embodiment 2
Normal mode
Under normal mode, system comprises: principal computer, control and data interface module, system bus backboard, main pulse program controling module, two from pulse protocol module, gradient control module, output interface, transmitter, receiver and gradient-driven module.
Principal computer is delivered to control and data interface module with steering order and data by the interface card and the stube cable of inside installation.Control at first is buffered in the instruction and data that the principal computer transmission comes in the storer of digital signal processor with data interface module, delivers on corresponding pulse protocol control module or the gradient control module through the system bus backboard through after certain format conversion; Simultaneously, it also receives the data that these modules transmit by the system bus backboard, passes back to principal computer then.The main pulse program controling module is controlled the work from pulse protocol control module and gradient control module, and produces the low speed control signal and receive external status signals by satellite interface.Outer synchronous signal then is used to make the operation and the external signal of The whole control table apparatus, after one's own heart electric switch control signal Synchronization.Control transmitter generation frequency, phase place and all adjustable quadrature radio-frequency signals of amplitude from pulse protocol control module 1.The simulating signal of coming by the nuclear magnetic resonance receiving system be converted to digital signal by receiver and handle after send back to from pulse protocol module 2, then through the system bus backboard by control and data interface module with the data back principal computer.Gradient control module control gradient modules produces gradient signal.
Deliver to the each several part of system behind the buffer clock signal that the master clock signal generator produces.
Claims (1)
1, a kind of digital nuclear magnetic resonance control console, this device is mainly by principal computer, control and data interface module, the system bus backboard, the main pulse program controling module, from the pulse protocol control module, the gradient control module, satellite interface, transmitter, receiver, gradient-driven and master clock signal generator are formed, it is characterized in that, (a), the main pulse program controling module adopts bus type to the control from pulse protocol control module and gradient control module, promptly use identical control signal wire, make them can be placed on the optional position of system bus backboard; (b), the main pulse program controling module, can inquire about the sign of add-on modules such as satellite interface, transmitter, receiver and gradient-driven automatically from pulse protocol control module and gradient control module, can detect the type of add-on module automatically; (c), this control desk device has used the if direct sampling technology of multi-mode variable sampling frequency; (d), this control desk device has used high speed Analog-to-Digital Conversion Technology, orthogonal digital down-conversion technique, digital decimation filtering technique, high-speed digital signal treatment technology and orthogonal radio frequency transmitter techniques simultaneously.
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| Application Number | Priority Date | Filing Date | Title |
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| CN 00128170 CN1207559C (en) | 2000-12-28 | 2000-12-28 | Digital nuclear magnetic resonance control console |
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| CN 00128170 CN1207559C (en) | 2000-12-28 | 2000-12-28 | Digital nuclear magnetic resonance control console |
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| CN1361418A true CN1361418A (en) | 2002-07-31 |
| CN1207559C CN1207559C (en) | 2005-06-22 |
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Cited By (8)
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| CN1831552B (en) * | 2006-04-20 | 2010-05-12 | 华东师范大学 | Integral nuclear magnetic resonance spectrometer control stage bused on USB bus |
| CN1871524B (en) * | 2003-10-24 | 2010-10-06 | 皇家飞利浦电子股份有限公司 | Diagnostic imaging system with user interface |
| CN102525470A (en) * | 2012-02-10 | 2012-07-04 | 北京汇影互联科技有限公司 | Compact peripheral component interconnect (cPCI)-based spectrometer for magnetic resonance imaging system and magnetic resonance imaging system |
| CN103309265A (en) * | 2013-05-21 | 2013-09-18 | 北京大学 | Small-sized nuclear magnetic resonance equipment controller used for one-dimensional spectrum analysis |
| CN101427149B (en) * | 2006-04-21 | 2013-09-18 | 皇家飞利浦电子股份有限公司 | Mr involving high speed coil mode switching between i-channel linear, q-channel linear, quadrature and anti-quadrature modes |
| CN105929348A (en) * | 2016-05-05 | 2016-09-07 | 中国科学技术大学 | Magnetic resonance spectrometer and apparatus for controlling magnetic resonance spectrometer based on FPGA |
| CN104303069B (en) * | 2012-05-14 | 2017-08-15 | 皇家飞利浦有限公司 | Feed circuit device for providing from radiofrequency signal to multiple coil parts of magnetic resonance coil system |
| WO2017190307A1 (en) * | 2016-05-05 | 2017-11-09 | 中国科学技术大学 | Magnetic resonance spectrometer and control apparatus for magnetic resonance spectrometer based on fpga |
Families Citing this family (1)
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| CN101413994B (en) * | 2008-11-28 | 2012-10-03 | 中国科学院武汉物理与数学研究所 | Signal receiving and transmitting device of digital magnetic nuclear resonance lock |
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2000
- 2000-12-28 CN CN 00128170 patent/CN1207559C/en not_active Expired - Fee Related
Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1871524B (en) * | 2003-10-24 | 2010-10-06 | 皇家飞利浦电子股份有限公司 | Diagnostic imaging system with user interface |
| CN1831552B (en) * | 2006-04-20 | 2010-05-12 | 华东师范大学 | Integral nuclear magnetic resonance spectrometer control stage bused on USB bus |
| CN101427149B (en) * | 2006-04-21 | 2013-09-18 | 皇家飞利浦电子股份有限公司 | Mr involving high speed coil mode switching between i-channel linear, q-channel linear, quadrature and anti-quadrature modes |
| CN102525470A (en) * | 2012-02-10 | 2012-07-04 | 北京汇影互联科技有限公司 | Compact peripheral component interconnect (cPCI)-based spectrometer for magnetic resonance imaging system and magnetic resonance imaging system |
| CN104303069B (en) * | 2012-05-14 | 2017-08-15 | 皇家飞利浦有限公司 | Feed circuit device for providing from radiofrequency signal to multiple coil parts of magnetic resonance coil system |
| CN103309265A (en) * | 2013-05-21 | 2013-09-18 | 北京大学 | Small-sized nuclear magnetic resonance equipment controller used for one-dimensional spectrum analysis |
| CN105929348A (en) * | 2016-05-05 | 2016-09-07 | 中国科学技术大学 | Magnetic resonance spectrometer and apparatus for controlling magnetic resonance spectrometer based on FPGA |
| WO2017190307A1 (en) * | 2016-05-05 | 2017-11-09 | 中国科学技术大学 | Magnetic resonance spectrometer and control apparatus for magnetic resonance spectrometer based on fpga |
| CN105929348B (en) * | 2016-05-05 | 2018-09-07 | 中国科学技术大学 | A kind of nuclear magnetic resonance spectrometer and the nuclear magnetic resonance spectrometer control device based on FPGA |
| US11002695B2 (en) | 2016-05-05 | 2021-05-11 | University Of Science And Technology Of China | Magnetic resonance spectrometer and control apparatus for magnetic resonance spectrometer based on FPGA |
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| CN1207559C (en) | 2005-06-22 |
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