CN1342497A - External electromagnetic drive controller of blood pump in artery - Google Patents
External electromagnetic drive controller of blood pump in artery Download PDFInfo
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- CN1342497A CN1342497A CN 00124718 CN00124718A CN1342497A CN 1342497 A CN1342497 A CN 1342497A CN 00124718 CN00124718 CN 00124718 CN 00124718 A CN00124718 A CN 00124718A CN 1342497 A CN1342497 A CN 1342497A
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Abstract
An external electromagnetic drive controller for the blood pump in artery is composed of miniature turbine pump, electromagnetic drive controller, power supply and machine casing. The turbine pump composed of permanent-maget rotor and blade wheel is arranged in the aorta. The electromagnetic drive controller arranged in external machine casing is composed of 1-2 electromagnetic drive coils, driven circuit, pulse distributer and controller. The said turbine pump is driven by the coupling of magnetic field. It can be used as artificial auxiliary heart.
Description
The present invention relates to a kind of external electromagnetic drive controller of blood pump in artery, be specially and drive a kind of super large air gap of control, promptly air gap is the blood pump dispatch from foreign news agency magnetic driving control device of running of the two poles of the earth permanent-magnetic synchronous motor rotor of 80-170mm.
At present, the sickness rate of cardiovascular and cerebrovascular disease becomes the first human killer according to the first place, and wherein, the serious consequence of cardiovascular diseases's development is the depletion of heart pump function.Number has only the only a few people to have an opportunity to do heart transplant operation among the cardiac necessarily every year, is minority and wherein success survives, and most cardiacs have no chance to obtain heart donor.Since nearly half a century, the knowledgeable people is absorbed in the mechanical blood circulation back-up system of exploitation, in the hope of temporary transient or permanent, partially or completely replaces nature heart pump, keeps the body blood circulation or promotes the damage heart to recover.In recent years, embedded type mechanical blood circulation and back-up system thereof has developed into higher stage, the i.e. appearance of implanted prosthetic heart and back-up system device thereof.At present, implanted prosthetic heart mostly is the anatomical replacement and is target, i.e. excision or damage patient's natural heart are analogous in the heart donor body and transplant like that, excise the patient's natural heart, implant and the optimum position that is connected to obtain artificial heart.The nature heart is abandoned in this anatomical replacement, get rid of natural heart up hill and dale and accepted the chance of new treatment, and the recent research result shows, in non-anatomical replacement, be under the support of functional replacement device, suffer the natural heart of the whole ＂ depletion in latter stage of multiple so-called ＂ of various pathological lesions strikes, can obtain the chance of surviving and recovering.The inventor is called ＂ power aortic valve ＂ in name, and application number is in 97104137.7 the application for a patent for invention, to have proposed a kind of functional replacement device, and a kind of ＂ rotor-impeller ＂ structural design has been simplified the structure of implant part greatly.The driving governor of this axial-flow machines blood pump can place in the human body, but its volume is big, and it is difficult to implant, the patient suffering; Also power supply lead wire to be pulled out externally, more increase patient's misery; Its maintenance difficulties is well imagined; If the driving governor of mechanical blood pump places human vitronectin, can overcome above-mentioned drawback,, the type of drive of the external permanent magnet rotation of the many employings of people so far, its mechanical shock is strong, and noise is big, and windage is big, the energy consumption height, air gap is little, less stable, and the control difficulty is bigger.
Purpose of the present invention, just provide the aortal permanent mechanical blood pump of a kind of disposable implantation, its driving governor and power supply all are positioned at external, and by wireless mode, promptly electromagnetic drive mode is controlled a kind of device of stable, the safe handling of mechanical blood pump.
Purpose of the present invention is by being connected with the electromagnetic driver coil of electric impulse signal, making it to produce alternating magnetic field, the two poles of the earth p-m rotor rotation of mechanical blood pump in the push body, and design that the miniature turbine of pump rotates synchronously realizes thereby drive.
External electromagnetic drive controller of blood pump in artery of the present invention comprises the miniature turbine pump, the Electromagnetic Drive controller, and power supply, the power line of band plug, casing and casing are hung and are worn part, and power supply links to each other with casing by power-line plug; Wherein: the miniature turbine pump is planted in aorta, and is made of rotor and impeller, and rotor is made with permanent magnet material, and impeller is made by biocompatible materials; The Electromagnetic Drive controller is located in the external casing, and the Electromagnetic Drive controller is by 1-2 Electromagnetic Drive coil, drive circuit, and pulsqe distributor and controller are formed, and when the Electromagnetic Drive coil was two, the angle between its axis was the 0-90 degree; Controller comprises microprocessor, and memorizer is regulated control circuit, and liquid crystal display and liquid crystal display drive decoder; Microprocessor comprises master clock and pulse generator; Pulsqe distributor links to each other with the pulse generator of the microprocessor of controller; Power supply is made up of control power supply and driving power; The front of casing is provided with panel, and the back side is worn part with the casing extension and linked to each other, and the panel of casing is provided with liquid crystal display, the control on and off switch, select to show the rotating speed button, select display driver voltage button, button resets/starts, select the manual governing button, select the automatic speed regulation button, driving power switch, driving voltage adjusting knob, the rotational speed regulation knob, step-out display lamp and supply socket; Liquid crystal display drives decoder with liquid crystal display and links to each other; The control on and off switch links to each other with supply socket; Select to show the rotating speed button and select display driver voltage button and liquid crystal display driving decoder to link to each other; The button that resets/start is selected the manual governing button, selects the automatic speed regulation button, and the rotational speed regulation knob links to each other with controller with the step-out display lamp; The driving voltage adjusting knob links to each other with the driving power switch; The driving power switch links to each other with supply socket; Distance between the iron core of Electromagnetic Drive coil and the miniature turbine pump is 50-170mm.
As the further improvement of external electromagnetic drive controller of blood pump in artery of the present invention, the rotor of described miniature turbine pump is the two poles of the earth Nd-Fe-B permanent magnet.
As the further improvement of external electromagnetic drive controller of blood pump in artery of the present invention, the impeller of described miniature turbine pump is that titanium alloy or polyformaldehyde are made.
As the further improvement of external electromagnetic drive controller of blood pump in artery of the present invention, the electromagnetic core of described Electromagnetic Drive coil is 0.2 cold-rolled silicon steel tape or permalloy.
As the further improvement of external electromagnetic drive controller of blood pump in artery of the present invention, when described Electromagnetic Drive coil was two, angle therebetween was 90 degree.
External electromagnetic drive controller of blood pump in artery of the present invention, described control power supply is 3-9V.
External electromagnetic drive controller of blood pump in artery of the present invention, described driving power are 48-150V.
External electromagnetic drive controller of blood pump in artery of the present invention, the rotating speed of described rotor are 10-170 revolutions per second.
In external electromagnetic drive controller of blood pump in artery provided by the present invention, the chip microprocessor in the controller can adopt MCS51 series, and storage and I/O control chip can adopt PSD31 series, technology maturation, and price is low, helps applying.
External electromagnetic drive controller of blood pump in artery provided by the present invention, described liquid crystal display is existing mature technology, for example, can adopt to drive coding chip 7211AM integrated package and liquid crystal display (LCD) chip ED-S805.
External electromagnetic drive controller of blood pump in artery of the present invention, described control power supply is fixing dc source, can use battery or city's piezoelectric transformer; Driving power is variable dc source, can utilize set of cells or city's piezoelectric transformer to obtain through variable potentiometer, and the knob of this variable potentiometer is the driving voltage adjusting knob on the machine shell panel.
The present invention transmits the principle of moment of torsion, i.e. torque T according to magnetic field:
T=K α * Kt*1/L*Fa*Ff*Sin (δ) wherein
K α be with two coil axises between the relevant coefficient of angle
Kt is a torque coefficient
L is the distance between magnetic bobbin core and the rotor
Fa is a coil magnetomotive force amplitude
Ff is a rotor magnetomotive force amplitude
δ is the angle between hot-wire coil magnetomotive force and the rotor magnetomotive force.When adopting an electromagnetic driver coil, the rotation direction of rotor is by its inceptive direction decision, and promptly by endarterial blood flow direction decision, therefore, single electromagnetic driver coil is suitable for the patient that heart still has faint function, as artificial accessory heart; When adopting two electromagnetic driver coils, the rotation direction of rotor is by the alive direction decision of institute in one of them electromagnetic driver coil, this sense of current is determined according to endarterial blood flow direction, an electromagnetic driver coil of back work plays booster action, therefore, two electromagnetic driver coils have the self-starting characteristic, are suitable for the patient that heart almost loses function, are used as artificial heart and use; Among the present invention, electric impulse signal is fed the electromagnetic driver coil in an orderly manner, make it produce alternating magnetic field, promote p-m rotor by endarterial blood flow direction rotation, its speed is controlled by pulse frequency, rotor rotation impeller is rotated, make endaortic blood be subjected to enough pressure, thereby promote flowing and circulation of blood, in other words, make the magnetic field coupling of intravital miniature turbine pump and external Electromagnetic Drive controller, produce moment of torsion, the miniature turbine pump rotates synchronously by controlled frequency, realize contactless energy delivery, reach by the intravital artificial heart of external wireless control and promote the purpose of blood flow, thereby can make artificial heart and human heart concurrent working, reach the non-anatomical replacement of heart, i.e. the purpose of functional replacement.To general crowd, the human body thoracic wall is 50-100m apart from the distance of miniature turbine pump, and this distance is big more, and the difficulty of its external driving is big more.
External electromagnetic drive controller of blood pump in artery provided by the present invention, during use, earlier the miniature turbine pump is planted in aorta, postoperative, the Electromagnetic Drive controller iron core in the casing of this device, subtend miniature turbine pump gets final product, and the distance between iron core and the miniature turbine pump is 50-170mm.
The advantage of external electromagnetic drive controller of blood pump in artery provided by the present invention: the permanent miniature blood pump of disposable implantation, it is external to need not to go between, and wound is little, and patient is painful few; Air gap wider range between Electromagnetic Drive controller and miniature turbine pump is 50-170mm; Because of the Electromagnetic Drive control device is placed on externally, be convenient to M R.
Below in conjunction with embodiment,, be described further external electromagnetic drive controller of blood pump in artery of the present invention.
Embodiment.
Fig. 1 is the external electromagnetic drive controller of blood pump in artery operation principle sketch map of present embodiment.
Fig. 2 is the pulsqe distributor circuit diagram of the external electromagnetic drive controller of blood pump in artery of present embodiment.
Fig. 3 is the drive circuit figure of the external electromagnetic drive controller of blood pump in artery of present embodiment.
Fig. 4 be present embodiment external electromagnetic drive controller of blood pump in artery controller pulse signal generator and regulate control circuit figure.
Fig. 5 is the display circuit figure of controller of the external electromagnetic drive controller of blood pump in artery of present embodiment.
Fig. 6 is that the machine shell panel of the external electromagnetic drive controller of blood pump in artery of present embodiment constitutes sketch map.
Fig. 7 is the electromagnetic driver coil drive p-m rotor principle schematic of present embodiment external electromagnetic drive controller of blood pump in artery.
Referring to Fig. 1-Fig. 4, Fig. 6 and Fig. 7.
The external electromagnetic drive controller of blood pump in artery of present embodiment comprises miniature turbine pump 1, the Electromagnetic Drive controller, and power supply, the power line of band plug, casing and casing are hung and are worn part, and power supply links to each other with casing by power-line plug; Wherein: miniature turbine pump 1 is planted in aorta, and is made of rotor and impeller, and rotor is made with permanent magnet material, and impeller is made by biocompatible materials; The Electromagnetic Drive controller is located in the external casing, and the Electromagnetic Drive controller is by 1-2 Electromagnetic Drive coil 2, drive circuit, and pulsqe distributor and controller are formed, and when Electromagnetic Drive coil 2 was two, the angle between its axis was the 0-90 degree; Controller comprises microprocessor, and memorizer is regulated control circuit, and liquid crystal display 9 and liquid crystal display drive decoder; Microprocessor comprises master clock and pulse generator; Pulsqe distributor links to each other with the pulse generator of the microprocessor of controller; Power supply is made up of control power supply and driving power; The front of casing is provided with panel, and the back side is worn part with the casing extension and linked to each other, and the panel of casing is provided with liquid crystal display 9, control on and off switch 10, select to show rotating speed button 11, select display driver voltage button 12, button 13 resets/starts, select manual governing button 14, select automatic speed regulation button 15, driving power switch 16, driving voltage adjusting knob 17, rotational speed regulation knob 18, step-out display lamp 19 and supply socket 20; Liquid crystal display 9 drives decoder with liquid crystal display and links to each other; Control on and off switch 10 links to each other with supply socket 20 with driving power switch 16; Select to show rotating speed button 11 and select display driver voltage button 12 and liquid crystal display driving decoder to link to each other; The button 13 that resets/start is selected manual governing button 14, selects automatic speed regulation button 15, and rotational speed regulation knob 18 links to each other with controller with step-out display lamp 19; Driving voltage adjusting knob 17 links to each other with driving power switch 16; Distance between the iron core of Electromagnetic Drive coil 2 and the miniature turbine pump 1 is 50-170mm.
The external electromagnetic drive controller of blood pump in artery of present embodiment, the rotor of described miniature turbine pump 1 are the two poles of the earth Nd-Fe-B permanent magnet.
The external electromagnetic drive controller of blood pump in artery of present embodiment, the impeller of described miniature turbine pump 1 are that titanium alloy is made.
The external electromagnetic drive controller of blood pump in artery of present embodiment, the electromagnetic core of described Electromagnetic Drive coil 2 are 0.2 cold-rolled silicon steel tape.
The external electromagnetic drive controller of blood pump in artery of present embodiment, when described Electromagnetic Drive coil 2 was two, angle therebetween was 90 degree.
The external electromagnetic drive controller of blood pump in artery of present embodiment, described control power supply is 5V.
The external electromagnetic drive controller of blood pump in artery of present embodiment, described driving power are 100V.
The external electromagnetic drive controller of blood pump in artery of present embodiment, the rotating speed of described rotor are 10-170 revolutions per second.。
The external electromagnetic drive controller of blood pump in artery of present embodiment, mechanical blood pump wherein adopts the miniature turbine pump, and its pump housing external diameter is 22mm, and length is 20mm, and the rotating shaft diameter is 2mm, and is simple in structure and firm; Under 80-100mm super large air gap situation, promptly in the body p-m rotor of pump to the distance of external Electromagnetic Drive controller in the 80-170mm scope, the rotating speed of rotor can 7000 rev/mins, when using water as experiment, can pump play water-column and reach one meter; Noiselessness, Maintenance free, after disposable the implanting, as long as rotor and Electromagnetic Drive controller continue synchronously, rotor just can be in the continuous firing state; This artificial heart can be described as the intra-arterial ahead turbine again, its miniature turbine is a minitype titanium alloy propeller-type impeller, its rotor is the two poles of the earth Nd-Fe-B permanent magnet, by rigid support cage supporting and fixing the implantation in the heart aorta lumen, rotor is with the rotation of certain rotating speed, make impeller produce dynamic pressure, keep or the circulation of auxiliary blood in human body in liquid; Used control power supply is a battery, and driving power is that set of cells obtains through variable potentiometer, and the knob of this variable potentiometer is the driving voltage adjusting knob on the machine shell panel.
The external electromagnetic drive controller of blood pump in artery of present embodiment, its operation principle is described as follows:
Figure 4 shows that the pulse signal generator in the controller, wherein the 80c32 chip is the MCS51 series microprocessor, the PSD311 chip is storage and I/O control integrated circuit, the TLC0831 chip is A/D converter (A/D), between 2 and 3 terminals of TLC0831 A/D converter, insert variable resistance RW3, this variable resistance RW3 is the rotational speed regulation knob that is located on the machine shell panel, terminal 6 output digital speed-control signals are given No. 8 terminals of 80c32 microprocessor, when selecting the manual governing button, terminal 3 ground connection of 80c32, the digital pulse signal (FREQ) of the manual frequency conversion of terminal 2 outputs of 80c32; When selecting the automatic speed regulation button, the terminal 3 of 80c32 is a high potential, promptly connects the control power supply, the digital pulse signal (FREQ) of the terminal 2 output automatic frequency-conversions of 80c32; Manual or automatic speed governing excursion is 10-170 revolutions per second; This pulse signal is by frequency divider U2 (74LS93) frequency division shown in Figure 2, after amplifier U5 (74LS08) amplifies, output to shift unit U1 (74LS164) on the one hand, on the one hand after amplifying once more, form tach signal (TACHO), the selection that outputs to panel shows on the rotating speed button; Through shift unit U1, nor gate U3 (74LS02), the formed pulse train Q1 of not gate U4 (74LS04), Q2, Q3 and Q4 as the input signal of drive circuit shown in Figure 3, make it by pulse sequence Q1, Q2, the sequential of Q3 and Q4 drives Electromagnetic Drive coil L1 and L2; When Q1 is that positive pulse and Q2 are when being low level, audion TR5 (D1138) and TR2 (B861) conducting, and audion TR1 (B861) ends with TR6 (D1138), make the electric current among the Electromagnetic Drive coil L1 flow to the COIL1 end by the COIL2 end, form a N-S polarity at L1 two ends unshakable in one's determination, make the p-m rotor of miniature turbine pump forward the relevant position to, the impeller of its drive is pressed the rotation of intra-arterial blood flow direction; When Q1 is a low level, when Q2 is positive pulse, TR1 and TR6 conducting, and TR5 and TR2 end, make the electric current among the Electromagnetic Drive coil L1 flow to the COIL2 end, form a S-N polarity, make the p-m rotor of miniature turbine pump be rotated further and above-mentioned opposite location at L1 two ends unshakable in one's determination by the COIL1 end; Pulse train Q3 and Q4 drive Electromagnetic Drive coil L2 with same principle, make L2 two ends unshakable in one's determination form N-S and the mutual alternative polarity of S-N, as shown in Figure 7, the axis angle α of Electromagnetic Drive coil L1 and L2, α are that 0-90 is when spending, by pulse sequence Q1, Q2, the sequential of Q3 and Q4, the p-m rotor that can make Electromagnetic Drive coil L1 and L2 drive the miniature turbine pump rotates, thus impeller is pressed the rotation of intra-arterial blood flow direction.
Referring to Fig. 5.
The external electromagnetic drive controller of blood pump in artery of present embodiment, liquid crystal display wherein adopts to drive coding chip 7211AM integrated package and liquid crystal display (LCD) chip ED-S805.
The external electromagnetic drive controller of blood pump in artery of present embodiment has two electromagnetic driver coils, has the self-starting characteristic, is suitable for the patient that heart almost loses function, can be used as artificial heart usefulness to this device, functional replacement nature heart.
Claims (9)
1. an external electromagnetic drive controller of blood pump in artery comprises miniature turbine pump (1), the Electromagnetic Drive controller, and power supply, the power line of band plug, casing and casing are hung and are worn part, and power supply links to each other with casing by power-line plug; It is characterized in that: miniature turbine pump (1) is planted in aorta, and is made of rotor and impeller, and rotor is made with permanent magnet material, and impeller is made by biocompatible materials; The Electromagnetic Drive controller is located in the external casing, and the Electromagnetic Drive controller is by 1-2 Electromagnetic Drive coil (2), drive circuit, and pulsqe distributor and controller are formed, and when Electromagnetic Drive coil (2) was two, the angle between its axis was the 0-90 degree; Controller comprises microprocessor, and memorizer is regulated control circuit, and liquid crystal display (9) and liquid crystal display drive decoder; Microprocessor comprises master clock and pulse generator; Pulsqe distributor links to each other with the pulse generator of the microprocessor of controller; Power supply is made up of control power supply and driving power; The front of casing is provided with panel, and the back side is worn part with the casing extension and linked to each other, and the panel of casing is provided with liquid crystal display (9), control on and off switch (10), select to show rotating speed button (11), select display driver voltage button (12), button (13) resets/starts, select manual governing button (14), select automatic speed regulation button (15), driving power switch (16), driving voltage adjusting knob (17), rotational speed regulation knob (18), step-out display lamp (19) and supply socket (20); Liquid crystal display (9) drives decoder with liquid crystal display and links to each other; Control on and off switch (10) links to each other with supply socket (20) with driving power switch (16); Select to show rotating speed button (11) and select display driver voltage button (12) and liquid crystal display driving decoder to link to each other; The button (13) that resets/start is selected manual governing button (14), selects automatic speed regulation button (15), and rotational speed regulation knob (18) all links to each other with controller with step-out display lamp (19); Driving voltage adjusting knob (17) links to each other with driving power switch (16); Distance between the iron core of Electromagnetic Drive coil (2) and the miniature turbine pump (1) is 50-170mm.
2. external electromagnetic drive controller of blood pump in artery according to claim 1, the rotor that it is characterized in that described miniature turbine pump (1) is the two poles of the earth Nd-Fe-B permanent magnet.
3. external electromagnetic drive controller of blood pump in artery according to claim 1, the impeller that it is characterized in that described miniature turbine pump (1) are that titanium alloy or polyformaldehyde are made.
4. according to claim 1 or 2 or 3 described external electromagnetic drive controller of blood pump in artery, the electromagnetic core that it is characterized in that described Electromagnetic Drive coil (2) is 0.2 cold-rolled silicon steel tape or permalloy.
5. according to claim 1 or 2 or 3 described external electromagnetic drive controller of blood pump in artery, when it is characterized in that described Electromagnetic Drive coil (2) is two, angle therebetween is 90 degree.
6. external electromagnetic drive controller of blood pump in artery according to claim 4, when it is characterized in that described Electromagnetic Drive coil (2) is two, angle therebetween is 90 degree.
7. external electromagnetic drive controller of blood pump in artery according to claim 1 is characterized in that described control power supply is 3-9V.
8. external electromagnetic drive controller of blood pump in artery according to claim 1 is characterized in that described driving power is 48-150V.
9. external electromagnetic drive controller of blood pump in artery according to claim 1, the rotating speed that it is characterized in that described rotor is 10-170 revolutions per second.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00124718 CN1342497A (en) | 2000-09-14 | 2000-09-14 | External electromagnetic drive controller of blood pump in artery |
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| Application Number | Priority Date | Filing Date | Title |
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| CN 00124718 CN1342497A (en) | 2000-09-14 | 2000-09-14 | External electromagnetic drive controller of blood pump in artery |
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| CN1342497A true CN1342497A (en) | 2002-04-03 |
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Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101056663B (en) * | 2004-11-16 | 2010-10-27 | 心血管微创医疗公司 | Remote data monitor for heart pump system |
| CN105327412A (en) * | 2015-11-26 | 2016-02-17 | 曾宪林 | Heart function assisting device used in operation |
| CN105343951A (en) * | 2015-11-26 | 2016-02-24 | 曾宪林 | Ventricular assist device |
| CN105498001A (en) * | 2015-11-26 | 2016-04-20 | 曾宪林 | Exocardial assisted-circulation artificial heart |
| GB2539643A (en) * | 2015-06-13 | 2016-12-28 | Lister Martin | Artificial heart |
| US10722631B2 (en) | 2018-02-01 | 2020-07-28 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use and manufacture |
| US11185677B2 (en) | 2017-06-07 | 2021-11-30 | Shifamed Holdings, Llc | Intravascular fluid movement devices, systems, and methods of use |
| US11511103B2 (en) | 2017-11-13 | 2022-11-29 | Shifamed Holdings, Llc | Intravascular fluid movement devices, systems, and methods of use |
| US11654275B2 (en) | 2019-07-22 | 2023-05-23 | Shifamed Holdings, Llc | Intravascular blood pumps with struts and methods of use and manufacture |
| US11724089B2 (en) | 2019-09-25 | 2023-08-15 | Shifamed Holdings, Llc | Intravascular blood pump systems and methods of use and control thereof |
| US11964145B2 (en) | 2019-07-12 | 2024-04-23 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of manufacture and use |
-
2000
- 2000-09-14 CN CN 00124718 patent/CN1342497A/en active Pending
Cited By (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101056663B (en) * | 2004-11-16 | 2010-10-27 | 心血管微创医疗公司 | Remote data monitor for heart pump system |
| GB2539643A (en) * | 2015-06-13 | 2016-12-28 | Lister Martin | Artificial heart |
| CN105327412A (en) * | 2015-11-26 | 2016-02-17 | 曾宪林 | Heart function assisting device used in operation |
| CN105343951A (en) * | 2015-11-26 | 2016-02-24 | 曾宪林 | Ventricular assist device |
| CN105498001A (en) * | 2015-11-26 | 2016-04-20 | 曾宪林 | Exocardial assisted-circulation artificial heart |
| US11185677B2 (en) | 2017-06-07 | 2021-11-30 | Shifamed Holdings, Llc | Intravascular fluid movement devices, systems, and methods of use |
| US11717670B2 (en) | 2017-06-07 | 2023-08-08 | Shifamed Holdings, LLP | Intravascular fluid movement devices, systems, and methods of use |
| US11511103B2 (en) | 2017-11-13 | 2022-11-29 | Shifamed Holdings, Llc | Intravascular fluid movement devices, systems, and methods of use |
| US10722631B2 (en) | 2018-02-01 | 2020-07-28 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use and manufacture |
| US11229784B2 (en) | 2018-02-01 | 2022-01-25 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use and manufacture |
| US12076545B2 (en) | 2018-02-01 | 2024-09-03 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of use and manufacture |
| US11964145B2 (en) | 2019-07-12 | 2024-04-23 | Shifamed Holdings, Llc | Intravascular blood pumps and methods of manufacture and use |
| US11654275B2 (en) | 2019-07-22 | 2023-05-23 | Shifamed Holdings, Llc | Intravascular blood pumps with struts and methods of use and manufacture |
| US11724089B2 (en) | 2019-09-25 | 2023-08-15 | Shifamed Holdings, Llc | Intravascular blood pump systems and methods of use and control thereof |
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