CN1341373A - High-concentration composite nutrient additive for phosphorus-saving type environment-protecting feed - Google Patents
High-concentration composite nutrient additive for phosphorus-saving type environment-protecting feed Download PDFInfo
- Publication number
- CN1341373A CN1341373A CN00123767A CN00123767A CN1341373A CN 1341373 A CN1341373 A CN 1341373A CN 00123767 A CN00123767 A CN 00123767A CN 00123767 A CN00123767 A CN 00123767A CN 1341373 A CN1341373 A CN 1341373A
- Authority
- CN
- China
- Prior art keywords
- vitamin
- phosphorus
- feed
- phytase
- calcium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000000996 additive effect Effects 0.000 title claims abstract description 27
- 239000000654 additive Substances 0.000 title claims abstract description 26
- 235000015097 nutrients Nutrition 0.000 title claims abstract description 20
- 239000002131 composite material Substances 0.000 title claims description 13
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 claims abstract description 30
- 108010011619 6-Phytase Proteins 0.000 claims abstract description 29
- 229940085127 phytase Drugs 0.000 claims abstract description 26
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims abstract description 22
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims abstract description 22
- QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 claims abstract description 22
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims abstract description 20
- LXNHXLLTXMVWPM-UHFFFAOYSA-N pyridoxine Chemical compound CC1=NC=C(CO)C(CO)=C1O LXNHXLLTXMVWPM-UHFFFAOYSA-N 0.000 claims abstract description 20
- 239000011647 vitamin D3 Substances 0.000 claims abstract description 20
- 229940021056 vitamin d3 Drugs 0.000 claims abstract description 20
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims abstract description 18
- 235000005282 vitamin D3 Nutrition 0.000 claims abstract description 18
- 229940055726 pantothenic acid Drugs 0.000 claims abstract description 16
- 239000011713 pantothenic acid Substances 0.000 claims abstract description 16
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 claims abstract description 15
- 239000011664 nicotinic acid Substances 0.000 claims abstract description 15
- 235000019161 pantothenic acid Nutrition 0.000 claims abstract description 15
- 235000001968 nicotinic acid Nutrition 0.000 claims abstract description 14
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims abstract description 12
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims abstract description 11
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 claims abstract description 11
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims abstract description 11
- 229930003471 Vitamin B2 Natural products 0.000 claims abstract description 11
- 229930003427 Vitamin E Natural products 0.000 claims abstract description 11
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims abstract description 11
- 229960002685 biotin Drugs 0.000 claims abstract description 11
- 235000020958 biotin Nutrition 0.000 claims abstract description 11
- 239000011616 biotin Substances 0.000 claims abstract description 11
- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims abstract description 11
- 229960002477 riboflavin Drugs 0.000 claims abstract description 11
- 235000019155 vitamin A Nutrition 0.000 claims abstract description 11
- 239000011719 vitamin A Substances 0.000 claims abstract description 11
- 235000019164 vitamin B2 Nutrition 0.000 claims abstract description 11
- 239000011716 vitamin B2 Substances 0.000 claims abstract description 11
- 235000019165 vitamin E Nutrition 0.000 claims abstract description 11
- 229940046009 vitamin E Drugs 0.000 claims abstract description 11
- 239000011709 vitamin E Substances 0.000 claims abstract description 11
- 229940045997 vitamin a Drugs 0.000 claims abstract description 11
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims abstract description 10
- FDJOLVPMNUYSCM-WZHZPDAFSA-L cobalt(3+);[(2r,3s,4r,5s)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2r)-1-[3-[(1r,2r,3r,4z,7s,9z,12s,13s,14z,17s,18s,19r)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-2 Chemical compound [Co+3].N#[C-].N([C@@H]([C@]1(C)[N-]\C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C(\C)/C1=N/C([C@H]([C@@]1(CC(N)=O)C)CCC(N)=O)=C\C1=N\C([C@H](C1(C)C)CCC(N)=O)=C/1C)[C@@H]2CC(N)=O)=C\1[C@]2(C)CCC(=O)NC[C@@H](C)OP([O-])(=O)O[C@H]1[C@@H](O)[C@@H](N2C3=CC(C)=C(C)C=C3N=C2)O[C@@H]1CO FDJOLVPMNUYSCM-WZHZPDAFSA-L 0.000 claims abstract description 10
- 229960000304 folic acid Drugs 0.000 claims abstract description 10
- 235000019152 folic acid Nutrition 0.000 claims abstract description 10
- 239000011724 folic acid Substances 0.000 claims abstract description 10
- RADKZDMFGJYCBB-UHFFFAOYSA-N pyridoxal hydrochloride Natural products CC1=NC=C(CO)C(C=O)=C1O RADKZDMFGJYCBB-UHFFFAOYSA-N 0.000 claims abstract description 10
- 239000011726 vitamin B6 Substances 0.000 claims abstract description 10
- 235000019158 vitamin B6 Nutrition 0.000 claims abstract description 10
- 229940011671 vitamin b6 Drugs 0.000 claims abstract description 10
- -1 amine nicotinate Chemical class 0.000 claims abstract description 3
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims description 28
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 22
- 235000016709 nutrition Nutrition 0.000 claims description 19
- 229960003512 nicotinic acid Drugs 0.000 claims description 15
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 15
- 239000008158 vegetable oil Substances 0.000 claims description 15
- 238000002372 labelling Methods 0.000 claims description 12
- 239000000853 adhesive Substances 0.000 claims description 10
- 229930003451 Vitamin B1 Natural products 0.000 claims description 9
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 claims description 9
- 229960003495 thiamine Drugs 0.000 claims description 9
- DPJRMOMPQZCRJU-UHFFFAOYSA-M thiamine hydrochloride Chemical compound Cl.[Cl-].CC1=C(CCO)SC=[N+]1CC1=CN=C(C)N=C1N DPJRMOMPQZCRJU-UHFFFAOYSA-M 0.000 claims description 9
- 235000010374 vitamin B1 Nutrition 0.000 claims description 9
- 239000011691 vitamin B1 Substances 0.000 claims description 9
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 8
- 235000019700 dicalcium phosphate Nutrition 0.000 claims description 8
- 239000003112 inhibitor Substances 0.000 claims description 7
- 230000035764 nutrition Effects 0.000 claims description 7
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 7
- 229940088417 precipitated calcium carbonate Drugs 0.000 claims description 6
- BCZXFFBUYPCTSJ-UHFFFAOYSA-L Calcium propionate Chemical compound [Ca+2].CCC([O-])=O.CCC([O-])=O BCZXFFBUYPCTSJ-UHFFFAOYSA-L 0.000 claims description 5
- 235000010331 calcium propionate Nutrition 0.000 claims description 5
- 239000004330 calcium propionate Substances 0.000 claims description 5
- 230000008878 coupling Effects 0.000 claims description 5
- 238000010168 coupling process Methods 0.000 claims description 5
- 238000005859 coupling reaction Methods 0.000 claims description 5
- AZJQQNWSSLCLJN-UHFFFAOYSA-N 2-ethoxyquinoline Chemical compound C1=CC=CC2=NC(OCC)=CC=C21 AZJQQNWSSLCLJN-UHFFFAOYSA-N 0.000 claims description 2
- 239000011859 microparticle Substances 0.000 claims description 2
- JXKPEJDQGNYQSM-UHFFFAOYSA-M sodium propionate Chemical compound [Na+].CCC([O-])=O JXKPEJDQGNYQSM-UHFFFAOYSA-M 0.000 claims description 2
- 235000010334 sodium propionate Nutrition 0.000 claims description 2
- 239000004324 sodium propionate Substances 0.000 claims description 2
- 229960003212 sodium propionate Drugs 0.000 claims description 2
- 235000015099 wheat brans Nutrition 0.000 claims description 2
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 abstract description 43
- 239000011574 phosphorus Substances 0.000 abstract description 37
- 229910052698 phosphorus Inorganic materials 0.000 abstract description 37
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 abstract description 15
- 241001465754 Metazoa Species 0.000 abstract description 15
- 239000011575 calcium Substances 0.000 abstract description 15
- 229910052791 calcium Inorganic materials 0.000 abstract description 15
- 244000144972 livestock Species 0.000 abstract description 15
- 244000144977 poultry Species 0.000 abstract description 12
- 229940088594 vitamin Drugs 0.000 abstract description 10
- 229930003231 vitamin Natural products 0.000 abstract description 10
- 235000013343 vitamin Nutrition 0.000 abstract description 10
- 239000011782 vitamin Substances 0.000 abstract description 10
- 238000004519 manufacturing process Methods 0.000 abstract description 9
- 238000005516 engineering process Methods 0.000 abstract description 6
- 230000004060 metabolic process Effects 0.000 abstract description 6
- 108090000790 Enzymes Proteins 0.000 abstract description 4
- 102000004190 Enzymes Human genes 0.000 abstract description 4
- 229940088598 enzyme Drugs 0.000 abstract description 4
- 239000003795 chemical substances by application Substances 0.000 abstract description 3
- DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 abstract description 2
- MJVAVZPDRWSRRC-UHFFFAOYSA-N Menadione Chemical compound C1=CC=C2C(=O)C(C)=CC(=O)C2=C1 MJVAVZPDRWSRRC-UHFFFAOYSA-N 0.000 abstract 2
- 239000012752 auxiliary agent Substances 0.000 abstract 2
- 229930003779 Vitamin B12 Natural products 0.000 abstract 1
- 238000013329 compounding Methods 0.000 abstract 1
- 235000019163 vitamin B12 Nutrition 0.000 abstract 1
- 239000011715 vitamin B12 Substances 0.000 abstract 1
- 235000019160 vitamin B3 Nutrition 0.000 abstract 1
- 239000011708 vitamin B3 Substances 0.000 abstract 1
- 235000012711 vitamin K3 Nutrition 0.000 abstract 1
- 239000011652 vitamin K3 Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 description 14
- 238000013461 design Methods 0.000 description 13
- 239000000463 material Substances 0.000 description 12
- 239000000047 product Substances 0.000 description 11
- 239000002994 raw material Substances 0.000 description 11
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 10
- 238000004128 high performance liquid chromatography Methods 0.000 description 10
- 230000008901 benefit Effects 0.000 description 9
- FAPWYRCQGJNNSJ-UBKPKTQASA-L calcium D-pantothenic acid Chemical compound [Ca+2].OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O.OCC(C)(C)[C@@H](O)C(=O)NCCC([O-])=O FAPWYRCQGJNNSJ-UBKPKTQASA-L 0.000 description 7
- 230000000050 nutritive effect Effects 0.000 description 7
- 239000000126 substance Substances 0.000 description 6
- 150000003722 vitamin derivatives Chemical class 0.000 description 6
- IMQLKJBTEOYOSI-GPIVLXJGSA-N Inositol-hexakisphosphate Chemical compound OP(O)(=O)O[C@H]1[C@H](OP(O)(O)=O)[C@@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@H](OP(O)(O)=O)[C@@H]1OP(O)(O)=O IMQLKJBTEOYOSI-GPIVLXJGSA-N 0.000 description 5
- IMQLKJBTEOYOSI-UHFFFAOYSA-N Phytic acid Natural products OP(O)(=O)OC1C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C(OP(O)(O)=O)C1OP(O)(O)=O IMQLKJBTEOYOSI-UHFFFAOYSA-N 0.000 description 5
- 238000009360 aquaculture Methods 0.000 description 5
- 244000144974 aquaculture Species 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 238000009472 formulation Methods 0.000 description 5
- 229910052757 nitrogen Inorganic materials 0.000 description 5
- 239000000467 phytic acid Substances 0.000 description 5
- 229940068041 phytic acid Drugs 0.000 description 5
- 235000002949 phytic acid Nutrition 0.000 description 5
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 description 4
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 description 4
- 239000004480 active ingredient Substances 0.000 description 4
- 230000003115 biocidal effect Effects 0.000 description 4
- 229960002079 calcium pantothenate Drugs 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 210000003608 fece Anatomy 0.000 description 4
- 108090000623 proteins and genes Proteins 0.000 description 4
- 102000004169 proteins and genes Human genes 0.000 description 4
- 230000002829 reductive effect Effects 0.000 description 4
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 4
- 235000013339 cereals Nutrition 0.000 description 3
- 150000001875 compounds Chemical class 0.000 description 3
- 239000000470 constituent Substances 0.000 description 3
- 238000011161 development Methods 0.000 description 3
- 230000007062 hydrolysis Effects 0.000 description 3
- 238000006460 hydrolysis reaction Methods 0.000 description 3
- FEMOMIGRRWSMCU-UHFFFAOYSA-N ninhydrin Chemical compound C1=CC=C2C(=O)C(O)(O)C(=O)C2=C1 FEMOMIGRRWSMCU-UHFFFAOYSA-N 0.000 description 3
- 238000012545 processing Methods 0.000 description 3
- 239000002699 waste material Substances 0.000 description 3
- 235000019750 Crude protein Nutrition 0.000 description 2
- LEVWYRKDKASIDU-QWWZWVQMSA-N D-cystine Chemical compound OC(=O)[C@H](N)CSSC[C@@H](N)C(O)=O LEVWYRKDKASIDU-QWWZWVQMSA-N 0.000 description 2
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 description 2
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 2
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 2
- 239000004472 Lysine Substances 0.000 description 2
- AYFVYJQAPQTCCC-UHFFFAOYSA-N Threonine Natural products CC(O)C(N)C(O)=O AYFVYJQAPQTCCC-UHFFFAOYSA-N 0.000 description 2
- 239000004473 Threonine Substances 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 229940036811 bone meal Drugs 0.000 description 2
- 239000002374 bone meal Substances 0.000 description 2
- 229960003067 cystine Drugs 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- XBDQKXXYIPTUBI-UHFFFAOYSA-N dimethylselenoniopropionate Natural products CCC(O)=O XBDQKXXYIPTUBI-UHFFFAOYSA-N 0.000 description 2
- 239000000428 dust Substances 0.000 description 2
- 230000029142 excretion Effects 0.000 description 2
- 230000003054 hormonal effect Effects 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 238000005342 ion exchange Methods 0.000 description 2
- 229960000310 isoleucine Drugs 0.000 description 2
- AGPKZVBTJJNPAG-UHFFFAOYSA-N isoleucine Natural products CCC(C)C(N)C(O)=O AGPKZVBTJJNPAG-UHFFFAOYSA-N 0.000 description 2
- 229930182817 methionine Natural products 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 235000005152 nicotinamide Nutrition 0.000 description 2
- 239000011570 nicotinamide Substances 0.000 description 2
- 239000002689 soil Substances 0.000 description 2
- 230000002195 synergetic effect Effects 0.000 description 2
- 238000012360 testing method Methods 0.000 description 2
- FXAYXAWEKSQBRX-FJXQXJEOSA-N 3-[[(2r)-2,4-dihydroxy-3,3-dimethylbutanoyl]amino]propanoic acid;pyridine-3-carboxylic acid Chemical compound OC(=O)C1=CC=CN=C1.OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O FXAYXAWEKSQBRX-FJXQXJEOSA-N 0.000 description 1
- 201000004569 Blindness Diseases 0.000 description 1
- 208000010711 Cattle disease Diseases 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 235000019739 Dicalciumphosphate Nutrition 0.000 description 1
- YCKRFDGAMUMZLT-UHFFFAOYSA-N Fluorine atom Chemical compound [F] YCKRFDGAMUMZLT-UHFFFAOYSA-N 0.000 description 1
- ZOKXTWBITQBERF-UHFFFAOYSA-N Molybdenum Chemical compound [Mo] ZOKXTWBITQBERF-UHFFFAOYSA-N 0.000 description 1
- 235000019483 Peanut oil Nutrition 0.000 description 1
- XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 description 1
- 235000019484 Rapeseed oil Nutrition 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 229940024606 amino acid Drugs 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000009395 breeding Methods 0.000 description 1
- 230000001488 breeding effect Effects 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 235000012343 cottonseed oil Nutrition 0.000 description 1
- 239000002385 cottonseed oil Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000002498 deadly effect Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000002950 deficient Effects 0.000 description 1
- 229940038472 dicalcium phosphate Drugs 0.000 description 1
- 229910000390 dicalcium phosphate Inorganic materials 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 239000003344 environmental pollutant Substances 0.000 description 1
- 210000003238 esophagus Anatomy 0.000 description 1
- 230000009969 flowable effect Effects 0.000 description 1
- 239000011737 fluorine Substances 0.000 description 1
- 229910052731 fluorine Inorganic materials 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 238000007710 freezing Methods 0.000 description 1
- 239000000383 hazardous chemical Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000000266 injurious effect Effects 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 235000010755 mineral Nutrition 0.000 description 1
- 229940029985 mineral supplement Drugs 0.000 description 1
- 238000005065 mining Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000011733 molybdenum Substances 0.000 description 1
- 229910052750 molybdenum Inorganic materials 0.000 description 1
- 210000000214 mouth Anatomy 0.000 description 1
- 229960003966 nicotinamide Drugs 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 238000005375 photometry Methods 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 231100000719 pollutant Toxicity 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000001902 propagating effect Effects 0.000 description 1
- 235000019260 propionic acid Nutrition 0.000 description 1
- OYSBZLVHMPNJMR-UHFFFAOYSA-N pyridine-3-carboxylic acid Chemical compound OC(=O)C1=CC=CN=C1.OC(=O)C1=CC=CN=C1 OYSBZLVHMPNJMR-UHFFFAOYSA-N 0.000 description 1
- IUVKMZGDUIUOCP-BTNSXGMBSA-N quinbolone Chemical compound O([C@H]1CC[C@H]2[C@H]3[C@@H]([C@]4(C=CC(=O)C=C4CC3)C)CC[C@@]21C)C1=CCCC1 IUVKMZGDUIUOCP-BTNSXGMBSA-N 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- GOLXNESZZPUPJE-UHFFFAOYSA-N spiromesifen Chemical compound CC1=CC(C)=CC(C)=C1C(C(O1)=O)=C(OC(=O)CC(C)(C)C)C11CCCC1 GOLXNESZZPUPJE-UHFFFAOYSA-N 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 239000002352 surface water Substances 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 239000013076 target substance Substances 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 230000001228 trophic effect Effects 0.000 description 1
- 235000013311 vegetables Nutrition 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Landscapes
- Fodder In General (AREA)
Abstract
The high-concentration compoiste nutrient additive for phosphorus-saving environment protecting feed is formed from nutrient component, phytase and auxiliary agent, and the described nutrient component contains vitamin A, vitamin D3, vitamin E, vitamin K3, vitamin BI, vitamin B2, vitamin B6, vitamin B12, vitamin PP or amine nicotinate, pantothenic acid, folic acid and biotin. By utilizing premixing technology and nutrient balance principle and according to the basic metabolism requirements of livestock and poultry and production requirements, it utilizes high-concentration compounding agent and one-step addition of auxiliary agent to meet a demand for 12 vitamins, at the sametime it utilizes the calcium and phosphorus released from natural grain by means of enzyme in animal body and utilizes natural phosphorus to meet demand for 70% or above that of phosphorus instead of isometric inorganic phosphorus in the feed.
Description
The present invention relates to additive for farm animal feed, refer to a kind of high-concentration composite nutrient additive of animal and fowl fodder especially.
Existing additive for raising poultry nutritive fodder prescription exists the shortcoming of following 5 aspects:
1, in the additive formulations of auxotype, do not have the function that reduces phosphorus and polluted by nitrogen, do not contain any potential nutritive value.
2, do not possess the function that reduces the feedstuff cost under the constant prerequisite of livestock and poultry economic performance keeping at least.
3, the kind of nutrition effective constituents is few in the prescription, and absolute content is low, causes the addition height, expends the feed formula space in a large number, and the addition of recommending variation greatly, and range factor (maximum addition/minimum addition) is greater than 2.5; The specific aim that prescription uses is poor; Definite difficulty height of optimum addition, the problem that use error is big are difficult to solve.
4, generally contain medicine, antibiotic, even the composition and the material that in feed, are not used by China's approval, as hormone, hormone like substance and other non-nutritional labeling appear in the feed, the safety to down-stream enterprise and livestock products consumer constitutes a threat to, and directly picking between composition often occur and resists and taboo; Non-target components mixes, the content height of impurity.
5, in the prescription design proportion between nucleus with best to need ratio to misfit be the inadequate natural endowment of existing prescription; Theoretical design moisture height, the stability of active ingredient can't meet the demands storing and add man-hour.
Aspect economic benefit and social benefit, existing additive formulations technical merit does not have further to reduce and optimize again the ability of feed cost in addition, does not directly take into consideration with the earth surface water source of protection breeding environment and the social benefit of underground water source yet.
The objective of the invention is provides a kind of phosphorus-saving type environment-protecting feed high-concentration composite nutrient additive at the existing deficiency of existing feed formula, and it can overcome the defective and the deficiency of prior art from above-mentioned several aspects.
At first explain title of the present invention:
Nourishing additive agent refers to that the material that is contained all classifies as nutritional labeling or the material (173 kinds) that allows use in prescription of the present invention.Do not contain any international organization, the country rules that comprise China and forbid material and medicine, hormone, hormone like substance, antibiotic and other any non-nutritional labeling of in comprising various animal and fowl fodders, adding.
Compound finger contains nutritional labeling or the material that surpasses more than the class in prescription of the present invention.
The content ratio of high concentration feeling the pulse with the finger-tip mark material is higher than 99% (dry matter basis).Association accessory substance and impurity are no more than 1%.
Phosphorus-saving type environment-protecting refers to that prescription of the present invention reduces the use amount and the protein level of Phos in the animal and fowl fodder, reduces the phosphorus that livestock and poultry are discharged in environment by excreta, from the prevention and control of pollution source aquaculture phosphorus that environment causes is polluted and polluted by nitrogen.
Core technology of the present invention for this reason is an additive formulations.It is to utilize pre-mixed technology and wait the nutrient balance principle, basic metabolism needs and production needs according to livestock and poultry, by composite dose of requirement that reaches supporting satisfied 12 kinds of vitamins with disposable interpolation of high concentration, utilize enzyme to discharge calcium and phosphorus in the natural grain in animal body simultaneously, utilize natural phosphorus satisfied 70% or above phosphorus requirement, substitute out the Phos of feed moderate.
According to this design, phosphorus-saving type environment-protecting feed high-concentration composite nutrient additive of the present invention is made up of nutrition, phytase and assistant; Described nutritional labeling is vitamin A, cholecalciferol, vitamin E, prokeyvit, vitamin B1, vitamin B2, vitamin B6, cobalamin, nicotinic acid, pantothenic acid, folic acid, biotin.
Wherein the addition of each nutrition is to contain in the per kilogram nourishing additive agent:
Vitamin A 45-55MIU;
Cholecalciferol 9-15MIU;
Vitamin E 100-135g;
Prokeyvit 8-13g (16-26as MSB or MNB);
Vitamin B1 6-13g;
Vitamin B2 23-35g;
Vitamin B6 12-22g;
Cobalamin 70-120mg;
Nicotinic acid or niacinamide 120-180g;
Pantothenic acid 35-80g;
Folic acid 2-5g;
Biotin 120-400mg;
Phytase 1.67-2.67mio.FTU (phytase activity unit is in 1,000,000).
Contained assistant is to be destaticizer/help adhesive agent, drier/mould inhibitor, excipient (Carrier) among the present invention, and their addition is respectively in the per kilogram additive: destaticizer/help adhesive agent 30-100g; Drier/mould inhibitor 1-2g; Excipient 80-300g.
Described destaticizer be for vegetable oil (vegetable oil) and ethoxyquinoline (EQ) coupling as destaticizer; Vegetable oil is the vegetable oil for low-freezing, low saturation, comprise cottonseed oil or rapeseed oil, also can be soybean oil and peanut oil, because moisture contained in the prescription of the present invention is low, the chemical purity height of target composition, the fineness height so must destatic, utilizes above-mentioned destaticizer promptly can reach the effect that destatics.
The described adhesive agent that helps is to be precipitated calcium carbonate (calcium carbonate) and vegetable oil coupling, and vegetable oil is also with vegetable oil used in the destaticizer, because active constituent content height among the present invention, target proportion is big, the physical characteristic difference is big, must take special measure to increase carrier and by the adhesive force between the carrier, and utilize precipitated calcium carbonate and vegetable oil coupling as helping the effect that adhesive agent promptly can reach increases adhesive force.
Excipient is commonly called as carrier, is middle matter calcium carbonate (calcium carbonate), also can use light weight microparticles type calcium monohydrogen phosphate (dicalcium phosphate) and wheat bran.
Drier and mould inhibitor are calcium propionate, provide two kinds of functions with a kind of material, also can be sodium propionate, utilize the strong absorptive of propionate, the effect of performance drier when moisture raises.And utilize the inhibitory action of propionic acid molecule, the effect of performance mould inhibitor when mouldy risk is arranged to microorganism.
Table 1 is the content and the potential nutritive value content of the corresponding nutritional labeling that can realize by unit addition (200 ± 20 gram/ton feed) in the per kilogram feed, vitamin in the feed of the vitamin in the composite nutrient additive prescription and this additive of application is corresponding relation of the same name, and phytase is non-corresponding relation, corresponding is the 9 kinds of material object hydrolysates (wherein phosphorus is expressed in 2 kinds of modes) of phytase and the energy of load with it.
Table 1
| Nutritional labeling and potential nutritive value content | |
| Vitamin A (IU) | ????8100-12100 |
| Cholecalciferol (IU) | ????1620-3300 |
| Vitamin E (mg) | ????18-30 |
| Prokeyvit (mg) | ????1.44-2.86 |
| Vitamin B1 (mg) | ????1.08-2.86 |
| Vitamin B2 (mg) | ????4.14-7.70 |
| Vitamin B6 (mg) | ????2.16-4.84 |
| Cobalamin (μ g) | ????12.6-26.40 |
| Nicotinic acid (mg) | ????21.6-39.6 |
| Pantothenic acid (mg) | ????6.3-17.6 |
| Folic acid (mg) | ????0.36-1.10 |
| Biotin (μ g) | ????21.6-88.0 |
| Can utilize phosphorus (g) | ????0.8-1.8 |
| Total phosphorus (g) | ????1.0-2.2 |
| Total calcium (g) | ????0.9-1.1 |
| Crude protein (g) | ????1.15-2.55 |
| Metabolizable energy (Kcal ME) | ????5-36.8 |
| Lysine (mg) | ????52-92 |
| Methionine (mg) | ????4-30 |
| Cystine (mg) | ????14-35 |
| Threonine (mg) | ????40-98 |
| Tryptophan (mg) | ????0-50 |
| Isoleucine (mg) | ????40-92 |
Nutrition in the table 1 and the content of potential value content in feed are to measure by method listed in the table 2 respectively.
Table 2
| External source is added in the feed nutritional labeling and potential nutritive value assay method | |
| Vitamin A (IU) | ????HPLC |
| Cholecalciferol (IU) | ????HPLC |
| Vitamin E (mg) | ????GC |
| Prokeyvit (mg) | ????HPLC |
| Vitamin B1 (mg) | ????HPLC |
| Vitamin B2 (mg) | ????HPLC |
| Vitamin B6 (mg) | ????HPLC |
| Cobalamin (μ g) | ????HPLC |
| Nicotinic acid (mg) | ????HPLC |
| Pantothenic acid (mg) | ????HPLC |
| Folic acid (mg) | ????HPLC |
| Biotin (μ g) | ????UV |
| Can utilize phosphorus (g) | The bio-digestion test |
| Total phosphorus (g) | The yellow photometry of molybdenum |
| Total calcium (g) | Permanganate titration |
| Crude protein (g) | Kjeldahl determination |
| Metabolizable energy (Kcal ME) | The biological metabolism test |
| Lysine (mg) | The ninhydrin colorimetric |
| Methionine (mg) | Ion-exchange |
| Cystine (mg) | Ion-exchange |
| Threonine (mg) | The ninhydrin colorimetric |
| Tryptophan (mg) | ????UV |
| Isoleucine (mg) | The ninhydrin colorimetric |
Operation principle of the present invention: the livestock and poultry of propagating artificially of the commercial use feed of must taking food.Calcium, phosphorus and vitamin earn a bare living with other and produce that necessary nutrient is the same all can't to rely on natural feed to satisfy the demand fully.Cereal accounts for 80-85% in the feed, and wherein containing 0.25-0.3% phosphorus cannot be utilized, and directly excretes with ight soil.The present invention is by the mode of additive; utilize phytase in the alimentary canal of livestock and poultry (oral cavity, esophagus, crop, stomach) with the feed hydrolysis of phytic acid; discharge and to utilize phosphorus and calcium, reached protection environment and the remarkable beneficial effect that reduces feed cost when satisfying the raising poultry nutritive requirement.
Now the Synergistic relation with each nutritional labeling in the prescription of the present invention is described in detail as follows:
(1) conspiracy relation of phytase-nicotinic acid
Phytase reduced the addition of nicotinic acid, and reason is the amount usable that phytase has increased tryptophan, in 1: 60 (tryptophan: ratio saving nicotinic acid nicotinic acid), the amplitude decline that the nicotinic acid additive is increased.
(2) conspiracy relation of phytase-pantothenic acid
Phytase improves the shank incidence of disease of animal, and the clean addition of pantothenic acid is descended.
(3) conspiracy relation of nicotinic acid-pantothenic acid
Because the functional cohesion of the two rises the addition of nicotinic acid, the addition of pantothenic acid descends, the ratio of the two (nicotinic acid: pantothenic acid) raise.
(4) conspiracy relation of calcium-phytase-cholecalciferol
The calcium constituent that the direct support of cholecalciferol is discharged by phytase hydrolysis phytic acid, suitable and sufficient cholecalciferol is the guarantee that phytase substitutes the horizontal calcium in feed Central Plains, do not have corresponding cholecalciferol phytase still can discharge calcium, but calcium can not be absorbed by animal.
(5) conspiracy relation of phosphorus-phytase-cholecalciferol
The P elements that the direct support of cholecalciferol is discharged by phytase hydrolysis phytic acid, suitable and sufficient cholecalciferol is the guarantee that phytase substitutes the horizontal phosphorus in feed Central Plains, do not have corresponding cholecalciferol phytase still can discharge phosphorus, but phosphorus metabolic process in animal body is affected.Owing to have the influence of cholecalciferol simultaneously, and calcium is to the absorption and the further influence of metabolism existence of phosphorus, so exist very special interactive relation between the three to calcium.
The detailed description of technical essential of the present invention
1, the present invention is composite with 12 kinds of vitamins and microbe-derived phytase high concentration first, separately independently on the trophic function basis, utilizes the synergistic function of the two appearance in vitamin and phytase performance;
2, in the additive formulations of auxotype, increase the function that reduces phosphorus and polluted by nitrogen, can directly substitute Phos raw materials such as calcium monohydrogen phosphate and bone meal; Contain the potential nutritive value that is higher than an own wt 1-2 order of magnitude;
3, according to digestion, absorption and the functional part of heterogeneity, take corresponding coordination design and property of raw material is modified, reach and the time synchronized at alimentary canal position and the position purpose of coincideing; Absolute content and ratio according to the 6 big factors that influence vitamin and enzyme require amount (expection production performance, kind, cultivation density, ambient temperature and humidity, feed are formed the processing technology of structure, feed) component design composition;
4, the cost economic performance analysis design that utilizes replaced target substance reduces the function of production of fodder cost under the constant prerequisite of the production performance that keeps livestock and poultry;
5, take the superelevation content concn, trace adds, fixedly addition design (200 ± 20 gram/ton), the purpose that the kind that reaches active ingredient is many, absolute content is high, addition is little.Save the feed formula space, the addition range factor has reduced by 3/4, only is 1.22.Eliminated the blindness that enterprise uses addition aborning;
6, adopt feed safety type and the design of livestock products safety-type environment-friendly products of not having medicineization fully.In prescription of the present invention, all offer keeping of animal and produce and need all be derived from nutriment.Key is that best dosage and ratio (comprise A:D3, nicotinic acid: pantothenic acid, D3: phytase, phytase: can utilize phosphorus, phytase: total calcium); Utilize the mutual work of different nutriments, collaborative additive effect to realize design object;
7, utilize non-drying means to reduce the theory design moisture of prescription significantly.Use the raw material composition (A, D3, phytase) of sensitivity has been taked back safeguard measure, reach under the constant prerequisite of the bioavailability of keeping various active ingredients after compound and improve stability, guarantee minimum active ingredient free of losses in 6 months;
8, utilize the after-processing technology of composition and flowable to keep good flowability;
9, utilize mixture homogeneity after excipient/help adhesive agent (low water lightweight calcium monohydrogen phosphate) guarantees the uniformity of this recipe ingredient and adds feed to;
10, specialization design, the animal applicable object of prescription is with strong points, and the processing applicable object is wide.
In sum, the present invention has following advantage: 1. pair advantage of protection environment
A. phosphorus and nitrogen are essential by growth of animals or poultry and production, and the phosphorus overwhelming majority of eating excretes again.Because the expansion of the development of aquaculture and intensification scale, phosphorus in the excreta and nitrogen have constituted grave danger that environment is polluted.Utilize enzyme to discharge phosphorus in the natural grain in animal body and satisfy 70% or above phosphorus requirement, therefore substitute out the Phos of feed moderate, make the excretion of phosphorus reduce more than 30%; The excretion of calcium reduces more than 3%; Total excreta amount (dry matter basis) reduces more than 2%; Directly reducing from pollution sources and culture the pollution of fowl industry to water source environment, is the most effective at present improvement method;
B. reduce the mining rate of phosphorus ore significantly, directly reduce the destruction of calcium monohydrogen phosphate enterprise, reduce the dust pollution of phosphorus ore surrounding environment and face of land contaminated water source to the orefield vegetation;
C. owing to reduced the use amount of calcium monohydrogen phosphate significantly, the inside and outside dust pollution of feed factory is reduced;
D. do not contain hazardous substance in the prescription of the present invention, do not produce harmful metabolite yet, in ight soil, do not have enrichment, meet the development trend and the requirement of nuisancelessization of excreta; 2. the advantage to economizing on resources
A. owing to contain the vegetable raw material of vast scale in the animal and fowl fodder, contain a large amount of phytic acid.Being the injurious factor that always can't remove over nearly 50 years, is the difficult problem that nutrient research field and feed aquaculture face.The phytase that utilization of the present invention is added, making turns waste into wealth, and discharges by the phytic acid chelating and mineral matter, amino acid and other nutriment that can't be utilized by livestock and poultry, and pollutant is converted into available resources;
B. phosphorus and protein are constrained resources valuable and the most in short supply in the world.The occupancy volume per person of China is all the more so.Prescription of the present invention is significantly reducing the southwest to when the excessive exploitation of phosphorus ore and saving the protein resource of high-quality, also a large amount of needed electric power of exploitation phosphorus ores and annual by the transport power of 60-70 ten thousand tons of feeds in southwest with calcium monohydrogen phosphate of saving;
C. to the vitamin ratio of prescription and the optimal design of addition addition and requirement are coincide to the full extent, reducing blindly increases the waste that addition causes.3. to improving the advantage of livestock products hygienic quality
A. the quality of improving livestock products is the prerequisite of aquaculture sustainable development.Prescription of the present invention reduces and finally stops using medicine, antibiotic and the material of the growth promotion/production performance of non-nutrition class that a solution is provided for promoting, product and parent all do not have bad material pollution and residual, develop to the direction that meets the livestock products safety requirements comprehensively;
B. provide the hygienic quality guarantee of feed for improving the livestock products quality.As producing the essential additive of feed, there is not the association accessory substance fully and non-object provides this guarantee.All do not produce the harmful substance composition in 6 months operating periods and after the foreseeable super shelf-life subsequently, thereby medicine, antibiotic and the material of growth promotion/production performance of non-nutrition class have been stopped to use from the raw material level and all adverse consequences that may cause, guarantee for Feed Enterprise provides the safe and sanitary of final products, make feed product meet safety requirements;
C. the fluorine poisoning that reduces significantly or thoroughly stopped to cause because of calcium monohydrogen phosphate;
Go mouldy risk and cause the potential risk of similar Britain deadly infectious diseases such as " mad cattle diseases " of the corruption of d. having avoided animality bone meal effectively.4. to improving the advantage of feed industry and aquaculture economic benefit
A. use prescription of the present invention can substitute the corresponding material quantity of an own wt 1-2 order of magnitude, directly reduce the transportation of enterprise's raw material and the volume of the circular flow of storing in a warehouse;
B. quality problems and economic loss that the feed potentially contaminated risk of stopping to cause because of the trace mineral supplement that contains nuisance causes;
C. pre-mixed technology and principle such as nutrient balance such as grade promptly reach supporting basic metabolism needs and the production requirement that satisfies livestock and poultry to 12 kinds of vitamins by composite dose of disposable optimal dose interpolation of high concentration.Also provide needed 70% or above utilized phosphorus and at least 3% utilizable calcium thereof simultaneously at least.Use and simplify, need not complicated calculations.Reduce the wrong probability of artificial metering simultaneously.For having solved, technical merit medium-sized and small enterprises on the low side and professional raising farmer blindly add excessive waste and not enough two hang-ups that lack that cause;
D. the most expensive nutrient at first is a phosphorus in the feed, secondly is protein.Reduce feed cost by substituting these two nutrients, the formulation weight space that discharges simultaneously provides chance for utilizing the least cost optimal design further to reduce cost;
Exemplify several embodiment below and further elaborate the present invention, these embodiment in order to explanation the present invention, are not that the present invention is done any type of restriction only.＜embodiment one 〉
The actual prescription one that feeds intake
| Raw material | ????％ |
| Vitamin A 500P | ????9 |
| Cholecalciferol 500 | ????1.8 |
| Vitamin E 50 | ????20 |
| Prokeyvit (MSB) | ????1.6 |
| Vitamin B1 (98%) | ????0.7 |
| Vitamin B2 80 | ????2.9 |
| Vitamin B6 (98%) | ????1.3 |
| Cobalamin (1%) | ????0.7 |
| Nicotinic acid (98%) | ????12.3 |
| D-calcium pantothenate (98%) | ????3.9 |
| Folic acid (95%) | ????0.3 |
| Biotin (2%) | ????0.6 |
| Phytase (10000G) | ????16.7 |
| Vegetable oil | ????0.5 |
| Precipitated calcium carbonate | ????8 |
| ?EQ(90) | ????0.006 |
| Middle matter calcium carbonate | ????19.6 |
| Calcium propionate | ????0.1 |
| Amount to | ????100 |
(annotate: the calcium pantothenate in the table is a raw material, and ' pantothenic acid ' that relates in the literary composition is nutritional labeling.According to international expression and the domestic general form of presentation of industry standard, when forming, uses the content of expressing a certain compound the content of nutritional labeling " pantothenic acid "; Refer to raw materials used ratio and produce ingredient proportion, use calcium pantothenate to represent.Calcium pantothenate is converted into pantothenic acid and plays a role in the body of taking in animal.The coefficient that the calcium pantothenate of generally acknowledging is converted into pantothenic acid is 0.92.)
By the each component fed batch in the last table, matter calcium carbonate, vitamin A 500P, cholecalciferol 500, vitamin B2 80, vitamin E 50, biotin H2, phytase during first comprises all, the back mixing of weighing was respectively stirred 1 minute, add second batch of all other component that comprise except that vegetable oil, stir and spray into simultaneously vegetable oil, environment temperature is crossed and is started heating apparatus when low and finish, and finished product is that mobile fine powder is granular.
＜embodiment two 〉
The actual prescription two that feeds intake
| Raw material | ????％ |
| Vitamin A 500P | ????10 |
| Cholecalciferol 500 | ????1.8 |
| Vitamin E 50 | ????20 |
| Prokeyvit (MSB) | ????1.6 |
| Vitamin B1 (98%) | ????0.7 |
| Vitamin B2 80 | ????2.9 |
| Vitamin B6 (98%) | ????1.3 |
| Cobalamin (1%) | ????0.7 |
| Nicotinic acid (98%) | ????12.3 |
| D-calcium pantothenate (98%) | ????3.9 |
| Folic acid (95%) | ????0.3 |
| Biotin (2%) | ????0.6 |
| Phytase (10000G) | ????25 |
| Vegetable oil | ????1 |
| Precipitated calcium carbonate | ????3.1 |
| EQ(90) | ????0.006 |
| Middle matter calcium carbonate | ????14.6 |
| Calcium propionate | ????0.17 |
| Amount to | ????100 |
By last table formula rate, all the other are with embodiment one.
＜embodiment three 〉
The actual prescription three that feeds intake
| Raw material | ????％ |
| Vitamin A 500P | ????9 |
| Cholecalciferol 500 | ????1.8 |
| Vitamin E 50 | ????20 |
| Prokeyvit (MSB) | ????1.6 |
| Vitamin B1 (98%) | ????0.6 |
| Vitamin B2 80 | ????2.9 |
| Vitamin B6 (98%) | ????1.2 |
| Cobalamin (1%) | ????0.7 |
| Nicotinic acid (98%) | ????12.3 |
| D-calcium pantothenate (98%) | ????3.9 |
| Folic acid (95%) | ????0.2 |
| Biotin (2%) | ????0.6 |
| Phytase (10000G) | ????25 |
| Vegetable oil | ????0.1 |
| Precipitated calcium carbonate | ????3.1 |
| EQ(90) | ????0.006 |
| Middle matter calcium carbonate | ????17 |
| Calcium propionate | ????0.05 |
| Amount to | ????100 |
By last table formula rate, all the other are with embodiment one.
Claims (4)
1, phosphorus-saving type environment-protecting feed high-concentration composite nutrient additive is characterized in that it is made up of nutrition, phytase and assistant; Described nutritional labeling is vitamin A, cholecalciferol, vitamin E, prokeyvit, vitamin B1, vitamin B2, vitamin B6, cobalamin, nicotinic acid, pantothenic acid, folic acid, biotin.
2, phosphorus-saving type environment-protecting feed high-concentration composite nutrient additive according to claim 1 is characterized in that containing in the per kilogram additive:
Vitamin A 45-55MIU;
Cholecalciferol 9-15MIU;
Vitamin E 100-135g;
Prokeyvit 8-13g;
Vitamin B1 6-13g;
Vitamin B2 23-35g;
Vitamin B6 12-22g;
Cobalamin 70-120mg;
Nicotinic acid 120-180g;
Pantothenic acid 35-80g;
Folic acid 2-5g;
Biotin 120-400mg;
Phytase 1.67-2.67mio.FTU.
3, phosphorus-saving type environment-protecting feed high-concentration composite nutrient additive according to claim 1 and 2, it is characterized in that described assistant is to be destaticizer/help adhesive agent, drier/mould inhibitor, excipient, their addition to be respectively in the per kilogram additive: destaticizer/help adhesive agent 30-100g; Drier/mould inhibitor 1-2g; Excipient 80-300g.
4, phosphorus-saving type environment-protecting feed high-concentration composite nutrient additive according to claim 3, it is characterized in that described destaticizer be for vegetable oil and ethoxyquinoline coupling as destaticizer; The described adhesive agent that helps is to be precipitated calcium carbonate and vegetable oil coupling; Drier and mould inhibitor are calcium propionate or sodium propionate; Excipient is middle matter calcium carbonate or light weight microparticles type calcium monohydrogen phosphate and wheat bran.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001237675A CN1213667C (en) | 2000-09-05 | 2000-09-05 | High-concentration composite nutrient additive for phosphorus-saving type environment-protecting feed |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CNB001237675A CN1213667C (en) | 2000-09-05 | 2000-09-05 | High-concentration composite nutrient additive for phosphorus-saving type environment-protecting feed |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1341373A true CN1341373A (en) | 2002-03-27 |
| CN1213667C CN1213667C (en) | 2005-08-10 |
Family
ID=4590120
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CNB001237675A Expired - Lifetime CN1213667C (en) | 2000-09-05 | 2000-09-05 | High-concentration composite nutrient additive for phosphorus-saving type environment-protecting feed |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1213667C (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101006846B (en) * | 2007-01-23 | 2011-04-27 | 天津生机集团有限公司 | Anti-stress nutrition additives for poultry and its preparation method |
| CN101485398B (en) * | 2009-02-25 | 2011-09-14 | 山东中基牧业发展有限公司 | Processing technique of composite premix feed for laying hen |
| CN101301026B (en) * | 2007-09-21 | 2011-12-07 | 天津生机集团有限公司 | Premixing feed for livestock and poultry containing multivitamins and method for preparing the same |
| CN102326712A (en) * | 2011-09-30 | 2012-01-25 | 南乐县金地饲料有限公司 | Complex vitamin premix for hybridized broiler chicken |
| CN103416596A (en) * | 2012-05-14 | 2013-12-04 | 河北飞龙家禽育种有限公司 | Vitamin premix for livestock and poultry |
-
2000
- 2000-09-05 CN CNB001237675A patent/CN1213667C/en not_active Expired - Lifetime
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101006846B (en) * | 2007-01-23 | 2011-04-27 | 天津生机集团有限公司 | Anti-stress nutrition additives for poultry and its preparation method |
| CN101301026B (en) * | 2007-09-21 | 2011-12-07 | 天津生机集团有限公司 | Premixing feed for livestock and poultry containing multivitamins and method for preparing the same |
| CN101485398B (en) * | 2009-02-25 | 2011-09-14 | 山东中基牧业发展有限公司 | Processing technique of composite premix feed for laying hen |
| CN102326712A (en) * | 2011-09-30 | 2012-01-25 | 南乐县金地饲料有限公司 | Complex vitamin premix for hybridized broiler chicken |
| CN103416596A (en) * | 2012-05-14 | 2013-12-04 | 河北飞龙家禽育种有限公司 | Vitamin premix for livestock and poultry |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1213667C (en) | 2005-08-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102626180B (en) | Amino acid chelating compound organic feed additive and production method thereof | |
| CN101828636B (en) | Feed formula for young meat ducks | |
| CN1709127A (en) | Composite fodder addiive of Chinese herbal medicine for goose fattening and its preparing process | |
| CN1857103A (en) | Compound pig feed additive and its preparing process | |
| CN104782886A (en) | Formula feed for laying hens during egg-laying peak period and preparation method of formula feed | |
| CN100333658C (en) | Tortoise and turtle feedstuff and preparing method | |
| KR101319097B1 (en) | Feed Supplement and method for making Fermented Green Tea Probiotics | |
| CN103734499A (en) | Aquatic organism feed | |
| CN109820092A (en) | A kind of feed addictive for improving sow bone strength, improving sow reproductive performance | |
| CN106578369A (en) | Pig feed recipe and manufacture method thereof | |
| CN108056260A (en) | Feed for beef cattle and preparation method thereof and the application in the special cultivation of Muslim beef | |
| CN1084019A (en) | The Chinese herbal medicine fattening agent | |
| CN1213667C (en) | High-concentration composite nutrient additive for phosphorus-saving type environment-protecting feed | |
| CN104413290A (en) | Special high-efficiency feed for mutton sheep | |
| CN107348214A (en) | A kind of feed for promoting goose growth containing edible fungus bran | |
| CN104161226A (en) | Feed for preventing broilers from feed passage in summer | |
| CN1943389A (en) | Additive of vegetarian feed and its fine material supplementing compound feed and complete feed | |
| RU2284703C1 (en) | Pig feeding method | |
| CN101904447A (en) | Shoat feed | |
| CN101715896B (en) | Low-residue green compound type dorking addition agent, preparation method and application thereof | |
| CN1033136C (en) | Compound Chinese herbs zeolite feed additive | |
| US10085464B2 (en) | Semi-solid animal feed blocks and method of making and using same | |
| CN112690364A (en) | Feed for preventing diarrhea of suckling pigs and preparation process thereof | |
| CN111685237A (en) | Preparation method of composite premixed pellet feed for minks, foxes and raccoon dogs | |
| CN117322515B (en) | Environment-friendly pig feed additive, feed and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| ASS | Succession or assignment of patent right |
Owner name: BEIJING DEJIA ANIMAL HUSBANDRY SCIENCE CO., LTD. Free format text: FORMER OWNER: BASF CHINA CO., LTD. Effective date: 20080718 |
|
| C41 | Transfer of patent application or patent right or utility model | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20080718 Address after: Beijing, Haidian District, North Third Ring Road West, No. 18, Ding Ding building, block B, 5 floor Patentee after: Beijing dejuxe Livestock Technology Co. Ltd. Address before: No. 7, Nanyang center, 75 Mody Avenue, Tsim Sha Tsui, Kowloon, Hongkong Patentee before: BASF China Co. Ltd |
|
| C56 | Change in the name or address of the patentee |
Owner name: TAIGAO NUTRITION TECHNOLOGY (BEIJING) CO., LTD. Free format text: FORMER NAME: BEIJING DEJIA ANIMAL HUSBANDRY SCIENCE AND TECHNOLOGY CO., LTD. |
|
| CP01 | Change in the name or title of a patent holder |
Address after: Beijing, Haidian District, North Third Ring Road West, No. 18, Ding Ding building, block B, 5 floor Patentee after: TAMCO Technology (Beijing) Co., Ltd. nutrition Address before: Beijing, Haidian District, North Third Ring Road West, No. 18, Ding Ding building, block B, 5 floor Patentee before: Beijing dejuxe Livestock Technology Co. Ltd. |
|
| C56 | Change in the name or address of the patentee | ||
| CP02 | Change in the address of a patent holder |
Address after: 100000 Beijing city Haidian District Dazhongsi Road 9, Beijing Science and technology building B block 410 Patentee after: TAMCO Technology (Beijing) Co., Ltd. nutrition Address before: Beijing, Haidian District, North Third Ring Road West, No. 18, Ding Ding building, block B, 5 floor Patentee before: TAMCO Technology (Beijing) Co., Ltd. nutrition |
|
| CP02 | Change in the address of a patent holder |
Address after: 100000 Room 606, block six, block C, 8 North Road, Haidian District, Beijing. Patentee after: TAMCO Technology (Beijing) Co., Ltd. nutrition Address before: 100000 B 410, Beijing Science and technology building, 9 East Road, Dazhong temple, Haidian District, Beijing. Patentee before: TAMCO Technology (Beijing) Co., Ltd. nutrition |
|
| CP02 | Change in the address of a patent holder | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20180706 Address after: 411100 wagun village, pan Tang Township, Yue Tang District, Xiangtan, Hunan Patentee after: Tai Gao nutrition technology (Hunan) Co., Ltd. Address before: 100000 Room 606, block six, block C, 8 North Road, Haidian District, Beijing. Patentee before: TAMCO Technology (Beijing) Co., Ltd. nutrition |
|
| TR01 | Transfer of patent right | ||
| CX01 | Expiry of patent term |
Granted publication date: 20050810 |
|
| CX01 | Expiry of patent term |