CN1334119A

CN1334119A - Litholysizing bear gall powder

Info

Publication number: CN1334119A
Application number: CN01128739A
Authority: CN
Inventors: 王继平
Original assignee: Individual
Current assignee: Individual
Priority date: 2001-07-26
Filing date: 2001-07-26
Publication date: 2002-02-06
Anticipated expiration: 2021-07-26
Also published as: CN1130219C

Abstract

A Chinese medicine for treating hepatoliary calculus is prepared from 29 Chinese-medicinal materials including bear gall, lysimachia, oriental wormwood, chicken's gizzard-skin, white peony root, etc. Its advantage is high curative effect.

Description

Litholysizing bear gall powder

Technical field

The present invention relates to a kind of with the pharmaceutical product of animals and plants as raw material, especially for the treatment liver and bile stone Litholysizing bear gall powder.

Background technology

Existing is the dissolved stone medicine of main component with the Chinese herbal medicine, as CN1158740, in its prescription with Radix Gentianae as main component because this medical herbs distributes seldom, make cost higher.

Summary of the invention

Litholysizing bear gall powder of the present invention is made up of the raw material of following weight portion: Herba Lysimachiae 6-180, Herba Artemisiae Scopariae 6-15, Endothelium corneum 10-20, the Radix Paeoniae Alba 10-30, Fructus Lycii 3-10, Rhizoma Polygoni Cuspidati 10-25, the Radix Aucklandiae 6-10, Fructus Aurantii 6-10, Pericarpium Citri Reticulatae Viride 6-30, Pericarpium Citri Reticulatae 10-25, Rhizoma Cyperi 6-10, Radix Curcumae 10-30 Natrii Sulfas 10-15, Radix Et Rhizoma Rhei 10-20, Folium Pyrrosiae 10-30, Radix Glycyrrhizae 5-10, Radix Astragali 10-30, Radix Bupleuri 6-10, Radix Scutellariae 6-10, Pumex 6-15 Fructus Crataegi 10-15, Massa Medicata Fermentata 6-15, Fructus Hordei Germinatus 6-15, Radix Clematidis 10-60, Rhizoma Coptidis 3-8, Concha Margaritifera 10-40, the Radix Rehmanniae 10-20, Fel Ursi 5-15, Alumen 6-10.

With above component levigation, 100 orders that sieve, encapsulated or make powder, honeyed pill, the watered pill and all can behind mixing, the disinfection by ultraviolet light.

The present invention has the effect of dispersing the stagnated live-QI to relieve the stagnation of QI, clearing heat secreting bile, the cloudy blood of nourishing the liver gallbladder, the stasis of blood of reducing phlegm, the molten hepatolith that disappears, and is used for liver and bile stone, acute and chronic cholecystitis, again fatty liver, gallbladder hydrops, urinary system calculus is had significant curative effect simultaneously.Have no wound, no pain, take medicine conveniently, have no side effect, calculus dissolving and excreting rate height, treat cholelithiasis 67 examples altogether, male's 24 examples, women's 43 examples, age 25-50 year 39 examples, person's 28 examples more than 50 years old, non-evident sympton or only show general indigestion symptom person 43 examples usually, stomachache arranged, feel sick, symptom's 24 examples such as vomiting, all patients are all through the Abdominal B type ultrasonography inspection more than twice or remake X line, CT, cholangiography inspection and make a definite diagnosis.Cure (the calculus image disappears, and symptom and sign disappear) 36 examples (53.73%), effectively (the calculus image dwindles, symptom and sign obviously alleviate) 22 examples (32.84%), invalid (calculus image no change, sx, sign or deposit) 9 examples (13.43%), total effective rate is 83.57%.

Below be the 67 routine clinical research reports of Litholysizing bear gall powder treatment cholelithiasis:

Cholelithiasis is surgical common disease, frequently-occurring disease, it is generally acknowledged and mostly be cholestasis, biliary tract antibacterial and parasitic infection, the cholesterol metabolism imbalance is principal element, the applicant since nineteen ninety-eight, to intend Litholysizing bear gall powder prescription therapeutic cholelithiasis 67 examples certainly, satisfactory effect now is summarized as follows in clinical practice:

1, clinical data

1.1 the patient of 67 routine patients for the special outpatient clinic treatment organized in treatment, male's 24 examples, women's 43 examples, age 25-50 year 39 examples, person's 28 examples more than 50 years old, non-evident sympton or only show general dyspepsia person's 43 examples usually, stomachache arranged, feel sick, symptom's 24 examples such as vomiting, all patients are all through the Abdominal B type ultrasonography inspection more than 2 times or remake X line, CT, gallbladder examination and make a definite diagnosis.

1.2 matched group 42 routine patients compare there was no significant difference from two groups of sexes of patient, age, the course of disease, the state of an illness, cardinal symptom, the professional aspect of treatment through making a definite diagnosis, and have comparability.

2, Therapeutic Method

2.1 the treatment group is made up of 29 pleasant impression Chinese medicines such as Fel Ursi, Natrii Sulfas, Alumen, Herba Artemisiae Scopariae, Radix Astragali, Radix Curcumae, Radix Et Rhizoma Rhei, names to be Litholysizing bear gall powder, drug dose is grasped flexibly according to patient age, body constitution, every day 3 times, and taking medicine after meal, 30 days is 1 course of treatment.

2.2 matched group is obeyed cholagogic and lithagogue tablet 3 times every day, each 5.

3, therapeutic outcome

3.1 criterion of therapeutical effect: adopt the whole nation unified diagnosis and curative effect judging standard, cure: sings and symptoms disappears, and imaging examination (B ultrasonic, PTC, ERCP, biliary tract vein or oral appearance must have wherein 2 kinds of inspection methods) calculus disappears; Produce effects: sings and symptoms alleviates, imaging examination, and calculus has obvious minimizing, reach more than 1/2, or calculus diminishes 1/2 above person; Effectively: sings and symptoms has and alleviates, and the imaging examination calculus reduces or the person of diminishing before the treatment; Invalid: the sings and symptoms no change, the imaging examination calculus does not have the changer.

3.2 two groups of total effectses relatively treatment are organized 67 examples, curing 36 examples (53.73%), produce effects 22 examples (32.84%), invalid 9 examples (13.43%), total effective rate is 86.57%; Matched group 42 examples, curing 3 examples (7.14%), produce effects 16 examples (38.10%), invalid 13 examples (53.76%), 45.24%, two group of cure rate difference of total effective rate has significance (ρ＜0.05).

4, brief summary

Clinical observation result shows, Litholysizing bear gall powder treatment cholelithiasis total effective rate is 86.57%, and cure rate is 53.73%, acts on really, evident in efficacy, obviously is better than the control drug cholagogic and lithagogue tablet.

Litholysizing bear gall powder serves as main the composition with Chinese herbal medicine, mineral medicine and animal drugs, has the effect of dispersing the stagnated live-QI to relieve the stagnation of QI, clearing heat secreting bile, nourishing the liver gallbladder cloudy blood, the stasis of blood of reducing phlegm, the molten hepatolith that disappears, full side's reasonable recipe, and compatibility is proper, thereby cholelithiasis is had the good curing effect.

Litholysizing bear gall powder is dosage form for oral administration, taking convenience, and no wound, no pain, clinical trial has no side effect, calculus dissolving and excreting rate height.

The specific embodiment 1:

Litholysizing bear gall powder of the present invention is made up of the raw material of following weight portion: Desmodium 6, oriental wormwood 15, interior golden 10, the root of herbaceous peony 30, Matrimony vine 10, giant knotweed 10, the banksia rose 10, Fructus Aurantii 6, Rascal 18, dried orange peel 18, rhizoma cyperi 8, root tuber of aromatic turmeric 20, Saltcake 15, rheum officinale 10, Shi Wei 30, Radix Glycyrrhizae 5, Give birth to the Radix Astragali 10, radix bupleuri 10, Huang Ling 6, bryozoatum 15 Living hawthorn 13, Divine Comedy 10, Fructus Hordei Germinatus 10, spirit be celestial 30, The coptis 5, mother-of-pearl 25, the dried rhizome of rehmannia 15, bear gall 8, Alum 8. With above component levigation, 100 orders that sieve, encapsulatedly behind mixing, the disinfection by ultraviolet light all can.

The specific embodiment 2:

Litholysizing bear gall powder of the present invention is made up of the raw material of following weight portion: Desmodium 180, oriental wormwood 6, interior golden 10, the root of herbaceous peony 30, Matrimony vine 3, giant knotweed 10, the banksia rose 6, Fructus Aurantii 10, Rascal 30, dried orange peel 10, rhizoma cyperi 10, root tuber of aromatic turmeric 10 Saltcake 10, rheum officinale 20, Shi Wei 10, Radix Glycyrrhizae 5, Give birth to the Radix Astragali 10, radix bupleuri 6, Huang Ling 10, bryozoatum 6 Living hawthorn 15, Divine Comedy 6, Fructus Hordei Germinatus 15, spirit be celestial 10, The coptis 8, mother-of-pearl 10, the dried rhizome of rehmannia 20, bear gall 5, Alum 10. With above component levigation, 100 orders that sieve, make powder behind mixing, the disinfection by ultraviolet light.

The specific embodiment 3: Litholysizing bear gall powder of the present invention is made up of the raw material of following weight portion: Desmodium 80, oriental wormwood 9, interior golden 15, the root of herbaceous peony 20, Matrimony vine 6, giant knotweed 18, the banksia rose 6, Fructus Aurantii 8, Rascal 6, dried orange peel 25, rhizoma cyperi 6, root tuber of aromatic turmeric 30g Saltcake 13, rheum officinale 15, Shi Wei 20, Radix Glycyrrhizae 7, Give birth to the Radix Astragali 30, radix bupleuri 10, Huang Ling 6, bryozoatum 15, Living hawthorn 10, Divine Comedy 15, Fructus Hordei Germinatus 6, spirit be celestial 60, The coptis 3, mother-of-pearl 40, the dried rhizome of rehmannia 10, bear gall 15, Alum 6. With above component levigation, 100 orders that sieve, make the water-bindered pill behind mixing, the disinfection by ultraviolet light.

Claims

1, a kind of Litholysizing bear gall powder that is used for the treatment of liver and bile stone is characterized in that being made up of the raw material of following weight portion: Herba Lysimachiae 6-180, Herba Artemisiae Scopariae 6-15, Endothelium corneum 10-20, the Radix Paeoniae Alba 10-30, Fructus Lycii 3-10, Rhizoma Polygoni Cuspidati 10-25, the Radix Aucklandiae 6-10, Fructus Aurantii 6-10, Pericarpium Citri Reticulatae Viride 6-30, Pericarpium Citri Reticulatae 10-25, Rhizoma Cyperi 6-10, Radix Curcumae 10-30 Natrii Sulfas 10-15, Radix Et Rhizoma Rhei 10-20, Folium Pyrrosiae 10-30, Radix Glycyrrhizae 5-10, Radix Astragali 10-30, Radix Bupleuri 6-10, Radix Scutellariae 6-10, Pumex 6-15, Fructus Crataegi 10-15, Massa Medicata Fermentata 6-15, Fructus Hordei Germinatus 6-15, Radix Clematidis 10-60, Rhizoma Coptidis 3-8, Concha Margaritifera 10-40, the Radix Rehmanniae 10-20, Fel Ursi 5-15, Alumen 6-10.