CN1313035A - Herbicidal composition and use thereof - Google Patents
Herbicidal composition and use thereof Download PDFInfo
- Publication number
- CN1313035A CN1313035A CN 01108964 CN01108964A CN1313035A CN 1313035 A CN1313035 A CN 1313035A CN 01108964 CN01108964 CN 01108964 CN 01108964 A CN01108964 A CN 01108964A CN 1313035 A CN1313035 A CN 1313035A
- Authority
- CN
- China
- Prior art keywords
- active ingredient
- water
- compound
- killer herbicide
- weed killer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The combination of herbicide(A)and(B)is capable of providing synergistic herbicide. A is substitutional N-phenoxylsulfonyl-N'-(4,6-disubstitutionalpyrimidine-2-yl)-urea corresponding to the formula(I)in claim 1, B is Quinclorac, Molinate, Butachlor, Propylamine, Dithiopr, Mefenacet, Fenoxaprop-ethyl, Dimepiperate, Pyrazolynate(Pyrazolate), Pyrazoxyfen, Benzofenap, Naproanilid, Bensulfuron-methyl, Pyrazosulfuron-ethyl, Cinosulfuron, Benfuresate, Bromobutide, Daimuron, Dimethametryn, Esprocarb, Pyributicarb, Butenachlor, Piperophos, Anilofos, Cinmethylin, Propanil, Imazosulfuron, NSK-850, HW-SW, JC-940, CH-900, and/or CIA-0051.
Description
The plant protection product of the present invention about in control unifacial leaf and broadleaf weed field, using.
From EP-A-0342569, known heterocyclic substituted phenoxy group sulfonylurea can be used for preventing and treating the unifacial leaf and the broadleaf weed of wide spectrum among the EP-A-0342568.They not only can be used as the Herbicidal agent but also can pass through foliage applying, and to unifacial leaf crops such as cereal, corn, paddy rice and jowar have shown good high selectivity.
As can be known, the mixture of active ingredient those important harmfulness weeds in preventing and treating cereal and paddy rice have shown synergistic effect from EP-A-0494988 and EP-A-480306.
For in cereal, those that exist in corn and paddy rice have the monocotyledon weed such as the amur foxtail of important economic implications in addition, wild oat, and barnyard grass grass or dog tail list are if the mixture of being touched upon above only selecting for use can not be obtained best control efficiency.
Surprisingly in biologic test, can find some weed killer herbicide active ingredients, when they and above mentioned individualized compound when using jointly, control for weeds has tangible synergy characteristics, is dominant so be mixed from the known binary of EP-A-0494988.
Of the present invention to liking Synergistic herbicidal agents, its characteristics are: it is by the effective content of the compd A of general formula (I) or tool salt and is selected from and contains a kind of of this compounds of B1 to B33, the composite preparation of two or more compd Bs, but by the effective content that contains A with only be selected from B1 to B9, except the composite preparation of a kind of compd B among B14 to B16 or the B28.
A) compound shown in the general formula (I) or their salt (compd A)
A in formula
1) R
1Be ethyoxyl, propoxyl group or isopropoxy and
R
2Be halogen, NO
2, CF
3, CN, C
1-C
4-alkyl, C
1-C
4-alkoxyl, C
1-C
4-alkylthio group or (C
1-C
4-alkoxyl)-carbonyl and
N is 1,2 or 3 or a
2) R
1Sometimes be the unsaturated C that halogen replaces
1-C
8-alkoxyl is unsubstituted C sometimes
1-C
6-alkoxyl, or (C
1-C
6-alkyl)-and S-, (C
1-C
6-alkyl)-SO-(C
1-C
6-alkyl)-SO
2, (C
1-C
6Alkyl)-and the base shown in the O-CO-, NO
2, CN or phenyl groups; Can also be C
2-C
8-alkene oxygen base or-alkynyloxy group and
R
2Be saturated or unsaturated C
1-C
8-alkyl, phenyl, phenoxy group, C
1-C
4-alkoxyl, C
1-C
4-alkylthio group, (C
1-C
4-alkoxyl)-and carbonyl, the representative R that the front is all
2Group can be by halogen, C
1-C
4-alkoxyl or C
1-C
4-alkylthio group replaces, or halogen, NO
2, C
1-C
4-alkyl sulphonyl or-sulfinyl and
N is 0,1,2 or 3 or a
3) R
1Be C
1-C
8-alkoxyl and
R
2Be C
2-C
8-alkenyl or-alkynyl, phenyl or phenoxy group are represented R
2Above-mentioned group be unsubstituted or by halogen, C
1-C
4-alkoxyl or-alkylthio group replaces, or C
1-C
4-alkyl sulphonyl or-alkyl sulphinyl and
N is 1,2 or 3 or a
4) R
12 at phenyl is halogen, methoxyl group, and ethyl or propyl group,
R
2On 6 of phenyl is (C
1-C
4-alkoxyl)-carbonyl and
N=1 and at all a
1)-a
4) in
R
3Be hydrogen, saturated or unsaturated C
1-C
8-alkyl or C
1-C
4-alkoxyl,
R
4, R
5Be respectively hydrogen, halogen, C
1-C
4-alkyl, C
1-C
4-alkoxyl, C
1-C
4-alkylthio group, above-mentioned last three groups are unsubstituted or by halogen, C
1-C
4-alkoxyl or C
1-C
4-alkylthio group replaces,
Y be O or S and
E is CH or N, B) is selected to contain a kind of of following compounds two or more compounds (compd B):
B1) 3,7-dichloroquinoline-8-carboxylic acid and their salt, (quinclorac)
B2) N-(ethylmercapto group-carbonyl)-azepan (molinate),
B3) N, N-diethyl-carbamic acid-4-chloro benzylthio ester (benthiocarb)
B4) N-(butoxymethyl)-2-chloro-N-(2,6-diethyl phenyl)-acetamide (butachlor)
B5) N-(2-propoxyl group ethyl)-2-chloro-N-(2,6-diethyl phenyl)-acetamide (the third careless amine)
B6) 3,5-two-(methyl mercapto-carbonyl)-2-difluoromethyl-4-(2-methyl-propyl)-6-trifluoromethyl-pyridine, (MON-7200, dithiopyr)
B7) 2-(1,3-benzothiazole-2-base oxygen base)-N-methyl-acetanil, (mefenacet)
B8) 2-(4-(6-chloro-benzoxazole-2-base oxygen base)-phenoxy group)-ethyl propionate, (oxazole diclofop-methyl)
B9) N-(2-phenyl-third-2-base-thiocarbonyl)-piperidines (dimepiperate)
B10) 4-(2,4-dichlorobenzene acyl group)-1,3-dimethyl-pyrazoles-5-base-toluyl-4-sulphonic acid ester (pyrazolate)
B11) 2-(4-(2,4-dichlorobenzene acyl group)-1,3-dimethyl-pyrazoles-5-base oxygen base)-acetophenone (pyrazoxyfen)
B12) 2-(4-(2, between 4-two chloro--toluyl)-1,3-dimethyl-pyrazoles-5-base oxygen base-4 '-methyl acetophenone (benzofenap)
B13) 2-(2-naphthoxy)-propionanilide (naphthalene aniline)
B14) a-(4,6-dimethoxypyridin-2-base-carbamoyl-amino-sulfonyl)-neighbour-methyl benzoate (bensulfuron-methyl)
B15) 5-(4,6-dimethoxypyridin-2-base-carbamoyl amino-sulfonyl)-1-methylpyrazole-4-carboxylic acid-methyl esters (pyrazosulfuron)
B16) 1-(4,6-dimethoxy-1,3,5-triazines-2-yl)-3-(2-(2-methoxyethoxy)-phenyl sulfonyl)-urea (ether is yellow grand)
B17) 2,3-dihydro-3,3-dimethyl benzofuran-5-base-esilate (benfuresate)
B18) the 2-bromo-3,3-dimethyl-N-(1-methyl isophthalic acid-phenylethyl)-butyramide (bromobutide)
B19) 1-(1-methyl isophthalic acid-phenylethyl)-3-P-toluyl-urea (daimuron)
B20) N
2-(1, the 2-dimethyl propyl)-N
4-ethyl-6-methyl mercapto-1,3,5-triazines-2,4-diamines (diformazan third second is clean)
B21) S-benzyl-1,2-dimethyl propyl (ethyl)-thiocarbamate (esprocarb)
B22) O-3-tert-butyl-phenyl-6-methoxyl group-2-pyridine radicals-(methyl)-thiocarbamate (pyributicarb, TSH-888)
B23) (Z)-N-but-2-ene base oxygen ylmethyl-2-chloro-2 ', 6 '-the diethyl acetanil (butenachlor, KH-218)
B24) S-2-methyl piperidine base carbonyl methyl-O, O-dipropyl sulphur substituted phosphate (piperophos)
B25) S-4-chloro-N-isopropyl-carbamyl ylmethyl-O, O-dimethyl-phosphorodithioate (anilofos)
B26) (1RS, 2SR, 4SR)-1,4-epoxy-right--2-base-2-methyl-benzylic ether (cinmethylin)
B27) N-(3, the 4-dichlorophenyl)-propionamide (Stam F-34)
B28)Imazosulfuron(TH-913)
B29) 2-chloro-N-(3-methoxyl group-2-thienyl)-methyl-2 ', 6 '-dimythyl acetanilide (NSK-850),
B30) 4-ethyoxyl benzo-2 ', 3 '-dihydro chloro anilid (HW-52),
B31) 1-diethylamino formoxyl-3-(2,4,6-trimethylbenzene sulfonyl)-1,2,4-triazole (CH-900),
B32) 3-(2-chlorobenzene methyl)-1-(1-methyl isophthalic acid-phenethyl)-urea (JC-940) and
B33) 2-(2-chloro-4-methylsulfonyl benzoyl group)-ring-1,3-diketone (ICIA-0051)
Compd A (compound shown in the formula (I)) is known in the cited Deutsche Bundespatent registration number of beginning.
Compound B-11)-B27) at " The Pesticide Manual " (" agricultural chemicals handbook ") British Crop Protection Council, 9th Ed., on the books in 1991; B1) " quinclorac " sees 749 pages; B2) " molinate " sees 594 pages; B3) " benthiocarb " sees 815 pages; B4) " butachlor " sees 106 pages; B5) " the third careless amine " sees 699 pages; B6) " dithiopyr " sees 321 pages; B7) " mefenacet " sees 544 pages; B8) “ oxazole diclofop-methyl " see 374 pages; B9) " dimepiperate " sees 289 pages; B10) " pyrazolate " sees 733 pages; B11) " pyrazoxyfen " sees 736 pages; B12) " benzofenap " sees 67 pages; B13) " naphthalene aniline " sees 610 pages; B14) " bensulfuron-methyl " sees 62 pages; B15) " pyrazosulfuron " sees 735 pages; B16) " ether is yellow grand " sees 174 pages; B17) " benfuresate " sees 58 pages; B18) " bromobutide " sees 97 pages; B19) " daimuron " sees 221 pages; B20) " diformazan third second is clean " sees 291 pages; B21) " esprocarb " sees 338 pages; B22) " pyributicarb " sees 741 pages; B23) " butenachlor " sees 108 pages; B24) " piperophos " sees 688 pages; B25) " anilofos " sees 36 pages; B26) " cinmethylin " sees 173 pages; B27) " Stam F-34 " (STAM) sees 715 pages.
Compd B 28) " Imazosulfuron " is known in patent registration No. EP-A-0238070 (TH-913).
Compd B 29) promptly be NSK-850, M.Ogasawara etc. are in " WeedResearch " (weeds research), (Tokyo), 1989, made report in the 131-137 page or leaf.
Compd B 30) promptly be HW-52, N.Ichizen etc. in " WeedResearch " (weeds research) (Tokyo), 1990, made report in the 261-267 page or leaf.
Compd B 31) promptly be CH-900, on the books in EP-332133.
Compd B 32) promptly be JC-940, on the books in J-60087254.
The weed killer herbicide of the present invention that especially meaningfully contains compound shown in the formula (I) or their salt, a in formula
1) R
1Be ethyoxyl, propoxyl group or isopropoxy and
R
2Be on 6 and above having given implication and
N is 0 or 1 or a
2) R
1Sometimes be undersaturated, by halogen, C
1-C
4-alkoxyl, C
1-C
4-alkylthio group or-sulfinyl or-sulfonyl, (C
1-C
4-alkoxyl)-and carbonyl, NO
2, the C that CN or phenyl have replaced
1-C
4-alkoxyl; Can also be C
2-C
5-alkenyloxy or C
2-C
4-alkynyloxy group and
R
2Be C
1-C
4-alkyl, C
2-C
5-alkenyl, (C
1-C
4-alkoxyl)-and carbonyl, C
1-C
4-alkoxyl or C
1-C
4-alkylthio group, these groups also replacement recited above can occur, or halogen and
N is 0 or 1 or a
3) R
1Be methoxyl group, ethyl or propyl group and
R
2Be 6-methoxycarbonyl or 6-ethoxy carbonyl and
N is 1 and at all a
1)-a
3) middle R
3Be hydrogen, C
1-C
4-alkyl, particularly hydrogen or methyl, R
4, R
5Be halogen, C
1-C
4-alkyl, C
1-C
4-alkoxyl or C
1-C
4-alkylthio group, wherein last described three groups are unsubstituted or by halogen, C
1-C
4-alkoxyl or C
1-C
4-alkylthio group replaces, and Y is O or S, particularly O, and E is CH or N, particularly CH,
Saturated or unsaturated alkyl and alkoxyl are alkyl corresponding straight chain or side chain or alkoxyl, and halogen refers to F, Cl, Br and I, preferred F and Cl.
Formula (I) compound can form salt, in its molecule-and SO
2The cation that hydrogen in the-NH-group can be suitable for using on agricultural replaces.These salt normally metal, particularly alkali metal, alkaline earth metal, be alkylation ammonium or organic amine salt sometimes.
Chemical formula to compd A noted earlier and B does not provide its stereochemical structure one by one.As long as stereoisomer is arranged, it just comprises all geometric isomers shown in these formulas, enantiomer and diastereoisomer and their mixture.For compd B 8) particularly including D-oxazole diclofop-methyl, and preferably it.
Compd A in the preferred weed killer herbicide contains formula A1, one or more compounds shown in A2 and the A3, and their structural formula is:
Below specific example, enumerate some desired active ingredient mixtures, but be not limited to this:
A1+ pyrazolate+mefenacet
A1+ pyrazolate+mefenacet+daimuron
A1+ pyrazolate+mefenacet+penta grass is clean
A1+ pyrazolate+esprocarb
A1+ pyrazolate+daimuron
A1+ pyrazolate+esprocarb+penta grass is clean
A1+ pyrazolate+benthiocarb
A1+ pyrazolate+benthiocarb+daimuron
A1+ pyrazolate+benthiocarb+penta grass is clean
A1+ pyrazolate+dimepiperate
A1+ pyrazolate+dimepiperate+daimuron
A1+ pyrazolate+dimepiperate+penta grass is clean
A1+ pyrazolate+TSH888
A1+ pyrazolate+TSH888+ daimuron
A1+ pyrazolate+TSH888+ penta grass is clean
A1+ pyrazolate+molinate
A1+ pyrazolate+molinate+daimuron
A1+++A1++A1+++A1+++A1++A1+++A1+++A1++NSK850A1++NSK850+A1++NSK850+A1++KH218A1++KH218+A1++KH218+A1++CH900A1++CH900+A1++CH900+A1++A1+++A1+++A1++A1+++A1+++A1++A1+++A1+++A1++A1+++A1+++A1++A1+++A1+++A1++A1+++A1+++A1++A1+++A1+++A1++TSH888A1++TSH888+A1++TSH888+A1++A1+++A1+++A1++A1+++A1+++A1++A1+++A1+++A1++NSK850A1++NSK850+A1++NSK850+A1++KH218A1++KH218+A1++KH218+A1++GH900A1++GH900+A1++GH900+A1++A1+++A1+++A1++A1+++A1+++A1++A1+++A1+++
Weed killer herbicide of the present invention has demonstrated good broad spectrum weeding function for unifacial leaf with important economic implications and dicotyledonous harmful plants.Those perennial weeds that are difficult to prevent and treat by the strong organ breeding of stem tuber, root or other vitality also can carry out effectively preventing with mixture of the present invention.So to prior to seeding, the dispenser relation is little before the bud or behind the bud.The representative kind of enumerating the unifacial leaf of some available chemical controls of the present invention and broadleaf weed below as an example, but not rising limit in this.
Monocotyledon weed comprises Avena, Lolium, and amur foxtail belongs to, phalaris arundinacea, Echinochloa, knotgrass, setaria and annual Cyperus and perennial Agropgron, the dog wheatgrass belongs to, the Cyperus that cogon and sorghum and lifetime are very long.
The grass that kills of broadleaf weed is composed as Bedstraw Viola, Veronica, lamium, Stellaria, Amaranthus, the Europe sinapsis alba belongs to, Ipomoea, Matricaria, abutilon, these annual weed of chrysanthemum harvest spp and perennial weed such as japanese bearbind belong to, Cirsium, Rumex is with the Li genus.
Weeds such as the arrowhead that occurs under this special growth conditions of paddy field belonged to, Waterplantain, Eleocharis, the sugarcane grass belongs to, and sand-grass belongs to, and active ingredient mixture of the present invention has good preventive effect too.
Compound of the present invention also can be prevented and treated monocotyledon weed with important economic implications such as the amur foxtail under corn and these specific crop growth conditions of paddy rice, wild oat, barnyard grass grass and green foxtail.
If weed killer herbicide of the present invention is imposed on upper soll layer before germination, can suppress the sprouting of weeds so fully, perhaps make it can only grow to leaf period, growth stops then, and is dead fully in 3 to 4 weeks of back of sprouting at last.
If after emerging, the mixture of active ingredient is imposed on the green portion of plant, after processing very fast can occur the growth stop, growth and development stage when weeds rest on dispenser or very fast death after certain hour are so the mode of the new weed killer herbicide of the application of the invention can be than the competition of early and enduringly getting rid of injurious weed and crops.
Though medicament of the present invention has excellent herbicidal for unifacial leaf and broadleaf weed, it is very little or do not have poisoning fully for the crops with important economic implications such as wheat, barley, rye, paddy rice and corn influence.Based on this reason, so medicament of the present invention is particularly suitable for optionally preventing and kill off noxious plant in the useful crops in land for growing field crops.
The herbicidal effect of active ingredient mixture of the present invention has exceeded the addition effect of desired single agent.The result of its synergy can significantly reduce the consumption of single active ingredient.In addition, also can prolong the drug effect of mixture, or accelerate the speed of action of medicament.These advantages of mixture of the present invention are that actual management of weeds has brought a lot of benefits, expenses for prevention and control are reduced or the speed of preventing and treating is faster or drug effect is longer, and the output of crops is improved.
Find that also active ingredient mixture of the present invention has safety and detoxication, promptly used active ingredient is for crops, as phytotoxicity reduction or the elimination fully of paddy rice.Especially meaningfully safener daimuron (compound B-11 9) and JC940 (compd B 32).
The mixed ratio of A and B can in very large range change; for the common mixed ratio of binary built 2: 1-1: between 200, for ternary or its mixed ratio of quaternary built (effective constituents A and 2 kinds or 3 kinds of active ingredient B) at 2: 1 or 2: 1: 1: 1-1: 200: 200 or 1: 200: 200: between 200.The pairing compound is depended in the selection of compound proportion, the growth and development stage of weeds, factors such as weeds spectrum and weather conditions.
The ratio of binary built preferred 1: 1-1: 100, the ratio of ternary built or quaternary built preferred 1: 1: 1 or 1: 1: 1: 1 to 1: 100: 100 or 1: 100: 100: between 100.Between the consumption of weed killer herbicide A preferred 10 and 100 gram/public affairs were inclined in mixture, the consumption of B was between 0.02 and 4.0 kilogram/public affairs are inclined.
Test by system can draw best usage ratio.When using daimuron as safener, its amount ratio is 1: 0.1-1:50, preferred 1: 1-1: 30, preferred especially 1: 10-1: 30.
Active ingredient mixture of the present invention can be the form that two kinds of components are mixed formulation, and common water dilutes it during use.Or the form of so-called canned mixture, be about to two kinds of components that are processed into preparation respectively dilute with water together.Decide according to predetermined biology and/or Chemical Physics parameter, compd A can be processed into different formulations with B or their composition.For example can reference as the formulation possibility: wetting powder (WP), water solube powder (SP), water-soluble concentrate, missible oil (EC), the aqueous solution (SL), emulsion (EN) is as oil-in-water and water-in-oil emulsion, solution that can spray or emulsion, with oil or water is the dispersant of matrix, suspending concentrate (SC), (suspension emulsion), solution that can be mixed with oil phase, capsule suspension (CS), pulvis (DP), impregnating agent, the granule of using in the soil or spreading fertilizer over the fields, miniature, spray-type, coating type granular agent and adsorption particle agent (GR), water-soluble granular formulation (SG), dispersible granules agent (WG) in water, ultralow black formulation, microcapsule formulations or cerate.
These single formulations are known in principle, for example are documented in: Winnacker-Kuchler, " Chemische Technologie " (chemical technology), Band7, C, Hanser Verlag Munchen, 4.A.1986; Van Valkenburg, " Pesticides Formulations " (formulations of pesticide), Marcel Dekker H.Y., 2nd Ed.1972-73; K.Martens, " Spray DryingHandfook " (atomized drying handbook), 3rd Ed, 1979; G.Goodwin Ltd.London.
Necessary formulation auxiliary material such as inert substance, surfactant, solvent and other additive equally also are known, for example be documented in: Watkins, " Handbook ofInsecticide Dust Diluents and Darriers " (agent of insecticide dust dilution agent and carrier handbook), 2nd Ed., Darland Books, Caldwell N.J.; H.V.Olphen, " Introduction to Clay Colloid Chemistry " (clay colloid the rudiments of chemistry), 2nd Ed., J.Wilay Sons, N.Y., Marsden, " Solvents Guide ", 2nd Ed., Intenscience, N.Y., 1950; McCntcheons, " Detergents and Emulsifiers Annual " (washing agent and emulsifier handbook), WC Pnbl.Corp., Ridgewood N.J.; Sieleyand Wood, " Encyclopedia of Surface Active Agents " (surfactant encyclopedia), Chem.Pulb.Co.Lnc.H.Y.1964; Schonfeldt, and " Grenzflachenaktive Athylenoxidaddukte " (surface-active ethylene oxide adduct ", Wiss, Verlagsgesell., Stuttgart 1976; Winnacker-Kuchler, " Chemische Technologie " (chemical technology), Band 7, G.Hauser Verlag Munchen, 4.Auf.1986.
On the basis of these formulations, they can be prepared into mixture with other the material with agricultural chemicals character such as other weed killer herbicide, bactericide or insecticide and fertilizer and/or growth regulator, for example make the finished product preparation form or as the canned mixture form.
Wetting powder is can homodisperse preparation in water; this preparation is compared with active ingredient; except thinner or inert substance; surfactant (the wetting agent that also contains ionic and/or nonionic; dispersant); polyethoxy alkylphenol class for example; polyethoxy aliphatic alcohols or fatty amine, fatty alcohol polyglycol ether sulfuric ester, alkane sulfonate; alkyl benzene sulfonate; sodium lignin sulfonate, 2,2 '-dinaphthyl methane-6; 6-sodium disulfonate, dibutyl naphthalene-sodium sulfonate or oleoyl N-methyltaurine sodium.In order to prepare wetting powder, weed killer herbicide active ingredient is for example used conventional equipment such as hammer mill, the air blast attrition mill with in airslide disintegrating mill, grind and simultaneously or mixing mutually of continuing with the formulation auxiliary material.
Missible oil is that active ingredient is dissolved in a kind of organic solvent, for example be dissolved in butanols, cyclohexanone, dimethyl formamide, in the mixture of dimethylbenzene or high boiling arene or hydro carbons or organic solvent, add one or more nonionics and/or ionic surfactant (emulsifier) again and be prepared from.Can do for example having of emulsifier use: alkyl aryl sulphonic acid calcium salt class and calcium dodecyl benzene sulfonate or nonionic emulsifier such as fatty acid polyethylene glycol ester, alkylaryl polyglycol ether, fatty alcohol polyglycol ether, expoxy propane-oxirane condensation product, alkyl, polyether, sorb alkane fatty acid ester, polyoxyethylene sorb alkane fatty acid ester or polyoxyethylene sorb ester.
Pulvis is with active ingredient and fine grain dispergated solid matter such as the talcum of being, natural clay such as kaolin, and bentonite and leaf wax soil or diatomite make through abrasive dust processing.
Suspending concentrate can be a matrix with water or oil.It can add some and be prepared from as top listed used surfactant in other formulation sometimes by means of commodity ball mill commonly used through wet-milling.
Emulsion, for example oil-in-water emulsion (EW) can be by means of agitator, colloid mill and/or static mixer, use water miscible organic solvent and use surfactant sometimes, the surfactant that has listed in other formulation as described above is prepared from.
The preparation of granule is active ingredient to be sprayed onto particulate inert material surface with absorption property or with the active ingredient polyvinyl alcohol, these adhesives of Sodium Polyacrylate or mineral oil adhere to sand, granule also can the active ingredient that some is suitable be processed into the method for common making granular fertilizer in the surface of carrier mass surfaces such as kaolin or particulate inert material.Also can mix processing when needing with fertilizer.
Conventional method such as atomized drying are used in the dispersible granules agent usually in the water, fluidized bed granulation, and tower granulation mixes and extruding and need not the method preparation of the inert material of solid with super mixer.
The percentage by weight that the preparation that uses on the agricultural contains effective constituents A or B usually is 0.1 to 99%, particularly 2 to 95%.The concentration of effective constituents A and B is different in the preparation.
The concentration that contains effective composition in the wetting powder is approximately 10-95% (weight), and wherein part is made up of formulation auxiliary material commonly used.The about 1-85% of the concentration of active ingredient (weight) in the missible oil, preferred 5-80% (weight).Pulvis contains the about 1-25% of effective composition (weight), mostly is 5-20% (weight) greatly.The solution that can spray contains the about 0.2-25% of effective composition (weight), preferred 2-20% (weight).Whether granule depends in part on that the active ingredient compound is in a liquid state or solid-state and use which type of particle auxiliary material and filler as its active constituent content of dispersible granules agent in the water.But usually in water in the dispersible granule active constituent content between 10 and 90% (weight).
In addition, the material that in above-mentioned active ingredient formulation, respectively also contains binding agent commonly used, wetting agent, dispersant, emulsifier, bleeding agent, preservative, antifreeze and solvent, filler, carrier and dyestuff, defoamer, volatilization inhibitor sometimes and regulate pH value and viscosity.
Use is diluted with conventional method sometimes with the formulation that commercial form provides, such as wetting powder, and missible oil, dispersant and dispersible granules agent dilutable water in water.Powderous preparations, soil-or spread fertilizer over the fields granule and the solution that can spray before use usually needn't be again with other inert substance dilution.
The consumption of formula (I) compound is because of external condition such as temperature, humidity, used weed killer herbicide type etc. and different.
The following examples are in order to make an explanation to the present invention: the A. formulation prepare embodiment a) pulvis be to mix by talcum as inert material with 10 parts heavy active ingredient composition of the present invention and 90 parts of weights, in a hammer mill, pulverize and get.B) in water, easily disperse; wetting powder is by the effective constituents A+B with 25 parts of weights; 64 parts of weights as containing of inert material of kaolinic quartz; mixing of 10 parts heavy lignin sulfonic acid potassium and 1 part of weight, in a rod mill, grind and get as the oleoyl N-methyltaurine sodium of wetting agent and dispersant.C) the dispersion concentrating agents that is easy to disperse in water is by the alkyl phenol polyglycol ether (Triton * 207) with 20 parts of heavy effective constituents A+B and 6 parts of weights, the different tridecanol polyglycol ether (8EO) of 3 parts of weights mixes mutually with 71 parts of scheelite wax mineral oil (more than the about 255-277 of boiling spread ℃), is milled to fineness below 5 microns and make in a ball mill.D) missible oil is the effective constituents A+B from 15 parts of weights, and the 75 parts heavy NONYL PHENOL ETHOXYLATED as emulsifier as the cyclohexanone of solvent and 10 parts of weights is made.E) dispersible granules agent preparation method is as follows in water: will
Effective constituents A+the B of 75 parts of weights,
10 parts heavy calcium lignosulfonates,
5 parts heavy NaLSs,
3 parts of reunion propenyls and
7 parts heavy kaolin mix mutually, grind in a rod mill, make the powder granulating by water is sprayed as granulation liquid in ebullated bed.F) dispersible granules agent preparation method is in water: will
Effective constituents A+the B of 25 parts of weights,
5 parts heavy 2,2 '-dinaphthyl methane-6,6 '-sodium disulfonate,
The oleoyl N-methyltaurine sodium of 2 parts of weights,
The POLYPROPYLENE GLYCOL of 1 part of weight,
The calcium carbonate of 17 parts of weights and,
The water of 50 parts of weights, homogenate grinds in advance in the colloid mill, and that continues further grinds in ball mill, more resulting suspended substance is sprayed and drying with a kind of one pack system shower nozzle in spray tower.G) the wetting powder preparation method is: with the effective constituents A of 3 parts of weights, and the active ingredient B of 30 parts of weights, the sodium lignin sulfonate of 3 parts of weights, the 63 parts heavy dioctyl sodium succinate that contains kaolinic quartz and 1 part of weight mixes mutually and grinds.H) process for producing granula is: will
0.1 part heavy effective constituents A,
1.5 part heavy active ingredient B,
0.5 part Neochol,
35 parts heavy bentonite,
62.9 part heavy talcum mixes mutually, grinds in a rod mill, makes powder granulating in an ebullated bed.Herbicide effect before biologic test embodiment 1. buds
It is in 9 centimetres the plastic basin that the seed of unifacial leaf and dicotyledon or piece root point are sowed at the diameter that contains dauk, topped with soil.Cultivate weeds in paddy field in water saturated soil, the water that adds in the Culture basin will arrive soil surface or surpass several millimeters of soil surfaces.The active ingredient composition of the present invention of wetting powder or missible oil concentrate form be will be mixed with then and, soil surface topped formula sprinkling or injection paddy field irrigation water made with this soup for the active ingredient of each single agent of the corresponding preparation of parallel test is converted into the many water slurries that amount of water is 600-800 liter/public affairs or the emulsion of many water by various dose.
Be placed on basin in the greenhouse after medication is handled and maintain the condition that is beneficial to weed growth.The situation of after test plant sprouts, being injured in 3 to 4 weeks by compare with untreated tester visual assessment hazard of plant or germination.Test confirms that weed killer herbicide of the present invention has the good herbicidal effect of wide spectrum for grass family and broad leaved weed.
In all cases, be discrepant between the calculated value of composition herbicidal effect and the measured value.The herbicidal effect calculated value of composition can calculate by the S.R.Colby formula: Calculation of Synegistic and antagonisticresponses of herticide Combination (synergy of weed killer herbicide and antagonism are calculated), Weeds15,20-22 page or leaf (1967).
Following formula is applicable to binary built:
For ternary built corresponding calculated formula be
In the formula
The percentage of being injured that X=is caused by weed killer herbicide A when being x kilogram/hectare at consumption;
The percentage of being injured that Y=is caused by weed killer herbicide B when being y kilogram/hectare at consumption;
The percentage of being injured that Z=is caused by weed killer herbicide B when being z kilogram/hectare at consumption;
The theory that E=is caused by weed killer herbicide A+B (or A+B+C) when being x kilogram/hectare at x+y (or x+y+z) the consumption percentage of being injured.
If the actual percentage of being injured is greater than the calculated value of expection, then the herbicidal effect of composition is greater than the effect of addition, that is demonstrated synergistic effect.
Active ingredient composition of the present invention has herbicide effect, and by the observation to single active ingredient herbicide effect, the herbicidal effect of composition is higher than the desired value that calculates by the Colby formula when using separately separately.So active ingredient composition is synergy.2. herbicide effect behind the bud
The seed or the piece root point of unifacial leaf and broadleaf weed are sowed in the plastic basin that contains dauk, topped with soil.Place the greenhouse that helps growth conditions to cultivate.The weeds dislocation that occurs in the paddy field surpassed in the basin on 2 centimetres on soil surface and at duration of test in water wherein cultivate.
To be mixed with the active ingredient composition of the present invention of wetting powder or missible oil concentrate form and be converted into the soup that amount of water is 300-600 liter/hectare by various dose for the active ingredient of each single agent of the corresponding preparation of parallel test, with the green portion of this medicine liquid spray plant, test plant is cultivated the herbicidal effect of about 3 to 4 all backs by the visual assessment preparation of comparing with untreated check plant down in the greenhouse the best growing condition.For weeds in paddy field, also weed killer herbicide active ingredient directly can be added in the irrigation water.Test confirms that medicament of the present invention has herbicidal effect behind the good bud for the grass family with important economic implications and broad leaved weed.According to the Colby theory analysis, medicament of the present invention has synergistic effect.
Embodiment 1
With paddy rice and barnyard grass grass in plastic basin, under greenhouse experiment, cultivate (temperature: 28/18 ℃, day/night; Relative moisture 60-80%).
Water to 2 centimetres of the depth of waters in basin and keep this water layer during whole test in the back of sprouting.Then at barnyard grass grass 1.5 leaves during the phase,, handle with active ingredient mixture of the present invention by means of the method that is poured onto by the formulated many water slurries of finished product or many aqueous emulsions in the water layer.
In about 3 weeks after processing, compare the evaluation test result by visual method and with untreated tester.
Listed the corresponding data of the mean value of per twice repeated test in the table 1.
Result of the test has clearly proved the synergistic effect of pairing mixture to the barnyard grass grass, compares it with single agent paddy rice is not damaged.
The herbicide effect and the selectivity of table 1 active ingredient mixture of the present invention
Abbreviation: ORSA=paddy rice
| Product (routine number) | Dosage (kg a. i./ha) | Herbicidal effect | |
| ORSA | ?ECCR | ||
| ?A1 | ?0,005 | ?10 | ?15 |
| ?B5 | ?0,025 | ?0 | ?65 |
| ?B32 | ?0,1 | ?0 | ?0 |
| ?B18 | ?0,3 | ?0 | ?0 |
| ?B33 | ?0,006 | ?0 | ?0 |
| ?B17 | ?0,02 | ?0 | ?5 |
| ?B25 | ?0,015 | ?0 | ?40 |
| A1+B32+B5 | ?0,005+0,1+0,025 | ?0 | ?85(70) |
| A1+B18+B5 | ?0,005+0,3+0,025 | ?0 | ?78(70) |
| A1+B33+B5 | ?0,005+0,006+0,025 | ?5 | ?80(70) |
| A1+B17+B25 | ?0,005+0,002+0,015 | ?0 | ?88(52) |
ECCR=barnyard grass grass
()=according to the desired value embodiment 2 of Colby formula
With two main weeds nutgrass flatsedges and the short arrowhead in the method cultivation Japanese water rice field that is similar to example 1.When the 1.5 leaf phases of nutgrass flatsedge, short arrowhead 1 leaf was handled with mixture of the present invention during the phase.
In this test, water layer is adjusted to more than the soil layer surface 3 centimetres high.Handle the 38th day evaluate efficacy in back.
Listed corresponding experiment data in the table 2.
The herbicidal effect of table 2 mixture of the present invention
Abbreviation: CYSE=nutgrass flatsedge
| Product (routine number) | Dosage (kg a.i./ha) | Herbicidal effect | |
| CYSE | ?SAPY | ||
| ?A1 | ?0,010 | ?35 | ?85 |
| ?B5 | ?0,225 | ?35 | ?85 |
| ?B7 | ?0,525 | ?80 | ?0 |
| ?B10 | ?0,600 | ?10 | ?60 |
| ?B18 | ?0,600 | ?70 | ?10 |
| ?B19 | ?0,750 | ?40 | ?0 |
| ?B25 | ?0,150 | ?75 | ?0 |
| ?A1+B19+B5 | ?0,01+0,60+0,225 | ?75(42) | |
| A1+B10+B7 | ?0,01+0,60+0,525 | ?95(88) | |
| A1+B19+B25 | ?0,01+0,75+0,15 | ?90(90) | 90(85) |
| A1+B18+B5 | ?0,01+0,75+0,525 | ?90(92) | 90(85) |
| A1+B17+B25 | ?0,01+0,60+0,225 | ?85(80) | |
The short arrowhead of SAPY=
()=press desired value embodiment 3 of Colby formula
Every basin (0.01m
3) in contain 2 strain paddy rice (2 leaf phase) and in the greenhouse, cultivate.For the mensuration triplicate of each active ingredient or each active ingredient mixture, the value described in the table meets by three independent mean values that obtain of measuring in other words.Active ingredient composition of the present invention and the corresponding single active ingredient that is made into are done to spray processing with the amount of 10 milliliters of flushing liquors two days later at rice transplanting.Plant exceeds at water layer and obtains under 2 centimetres of conditions of upper soll layer cultivating.The actual working concentration of active ingredient is listed in the following table.Measured the weight of root and tender stem on the 25th day after the medication, and compare with untreated contrast weight (100%).
Safe effect (the high 0.5cm of plant) to paddy rice
The heavy 14.8g of the tender stem of untreated tester, the heavy 6.2g of root is equivalent to 100%.
| Compound | Usage amount (g a.i./10a) | Growing state (%) | |
| Tender stem | Root | ||
| ?A1+ | ?6 | ?82 | ?61 |
| ?A1+B19 | ?6+30 | ?98 | ?92 |
| ?A1+B19 | ?6+60 | ?100 | ?100 |
| ?A1+B19 | ?6+120 | ?100 | ?98 |
| ?A1+B19 | ?12 | ?67 | ?52 |
| ?A1+B19 | ?12+30 | ?91 | ?90 |
| ?A1+b19 | ?12+60 | ?98 | ?98 |
| ?A1+B19 | ?12+120 | ?100 | ?98 |
| ?B19 | ?120 | ?100 | ?100 |
| Untreated tester | ?100 | ?100 | |
Safe effect on paddy rice (the high 2.0cm of plant)
The heavy 17.4g of the tender stem of untreated control, the heavy 8.1g of root is equivalent to 100%.The synergistic effect of example 4 Dymuron on paddy rice
| Compound | Usage amount (g a.i./10a) | Growing state | |
| Tender stem | Root | ||
| ?A1 | ?6 | ?99 | ?69 |
| ?A1+B19 | ?6+30 | ?100 | ?92 |
| ?A1+B19 | ?6+60 | ?100 | ?97 |
| ?A1+B19 | ?6+120 | ?100 | ?100 |
| ?A1 | ?12 | ?98 | ?64 |
| ?A1+B19 | ?12+30 | ?100 | ?96 |
| ?A1+B19 | ?12+60 | ?100 | ?98 |
| ?A1+B19 | ?12+120 | ?100 | ?100 |
| ?B19 | ?120 | ?100 | ?100 |
| Untreated tester | 100g | ?100g | |
Seed or the piece root point of barnyard grass grass, firefly Lin, short arrowhead, nutgrass flatsedge and water chestnut are sowed at plastic basin (0.08m
2) in, topped with soil, be put in the greenhouse that helps growing and cultivate.Active ingredient composition of the present invention and the corresponding single active ingredient that is mixed with dosage form are applied to (0 leaf phase) on the still inchoate barnyard grass grass of leaf with 10 milliliters of form of suspension that contain wetting powder.Water in basin layer more than soil layer 3 centimetres.Medication is handled and was measured the plant fresh weight in back 28 days.The plant fresh weight that the data fit of listing in the following table has been handled is to the ratio of untreated check plant.
Abbreviation: the short arrowhead CYPSE=of ECHR=barnyard grass grass SCPJU=firefly Lin SAGPY=nutgrass flatsedge ELOKU=water chestnut is concerning untreated check plant 1) 71.0 its growing states of gram barnyard grasses grass are equivalent to 100%.2) 4.6 its growing states of gram firefly Lin are equivalent to 100%.3) its growing state of the short arrowhead of 5.8 grams is equivalent to 100%.4) 43.0 its growing states of gram nutgrass flatsedge are equivalent to 100%.5) 8.1 its growing states of gram water chestnut are equivalent to 100%.
| Compound | Consumption (g a.i./10a) | The % of untreated contrast (fresh weight) ECHR SCPJU SAGPY CYPSE ELOKU |
| ?A | ?3 | ??28???????3????????6????????15???????0 |
| ?A+B19 | ?3+30 | ??26???????0????????4????????14???????0 |
| ?A+B19 | ?3+60 | ??20???????0????????5????????11???????0 |
| ?A+B19 | ?3+120 | ??25???????0????????6????????10???????0 |
| ?B19 | ?120 | ??47??????15???????100??????100???????45 |
| ?100?????100???????100??????100??????100 |
Claims (5)
1. weed killer herbicide, it comprises following formula: compound (A1) or its salt
And, following formula: compound B8) 2-[4-(6-Lv Bing oxazole-2-base oxygen base)-phenoxy group]-ethyl propionate
Wherein the consumption of compound (A1) is a 10-100 gram/hectare, and the consumption of compd B 8 is the 0.01-4.0 kg/ha.
2. the method for preparing claim 1 weed killer herbicide is characterized in that compound (A1) is mixed with compd B 8.
3. application rights requires 1 weed killer herbicide to prevent and kill off the purposes that does not need plant, it is characterized in that at the surface applied in these unwanted plants or their the growth plot weed killer herbicide according to claim 1.
4. according to the purposes of claim 3, it is characterized in that controlling weeds in useful plant.
5. according to the purposes of claim 4, it is characterized in that useful plant refers to wheat, barley, black rice and corn.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEP4209475.5 | 1992-03-24 | ||
| DE4209475A DE4209475A1 (en) | 1992-03-24 | 1992-03-24 | Synergistic herbicide mixt. - contains substd. N-phenoxy-sulphonyl-N'-(4,6-di:substd. pyrimid-2-yl)urea and another herbicide |
| DEP4241629.9 | 1992-12-10 | ||
| DE19924241629 DE4241629A1 (en) | 1992-12-10 | 1992-12-10 | Synergistic herbicidal compsns. - contg. sulphonyl-urea deriv. and other herbicide |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 93103348 Division CN1076585A (en) | 1992-03-24 | 1993-03-23 | Synergistic herbicidal agents and safener |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1313035A true CN1313035A (en) | 2001-09-19 |
Family
ID=25913142
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 93103348 Pending CN1076585A (en) | 1992-03-24 | 1993-03-23 | Synergistic herbicidal agents and safener |
| CN 01108964 Pending CN1313035A (en) | 1992-03-24 | 2001-02-28 | Herbicidal composition and use thereof |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 93103348 Pending CN1076585A (en) | 1992-03-24 | 1993-03-23 | Synergistic herbicidal agents and safener |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPH0687706A (en) |
| CN (2) | CN1076585A (en) |
| IT (1) | IT1270985B (en) |
| TW (1) | TW296331B (en) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR970061071A (en) * | 1996-02-09 | 1997-09-12 | 가시와기 시로 | Herbicide composition |
| US9247735B2 (en) * | 2011-01-19 | 2016-02-02 | Rotam Agrochem International Company Limited | Crop plant-compatible herbicidal compositions containing herbicides and safeners |
| CN102365964A (en) * | 2011-11-03 | 2012-03-07 | 陕西美邦农药有限公司 | Herbicidal composition containing ethoxysulfuron and quinclorac |
| CN102396481B (en) * | 2011-11-15 | 2014-06-18 | 陕西美邦农药有限公司 | Weeding composition containing ethoxysulfuron and amide compound |
| CN103749503B (en) * | 2013-12-24 | 2016-01-27 | 江苏天容集团股份有限公司 | Expand the Herbicidal composition for paddy fields of weeding scope |
| CN104351235A (en) * | 2014-09-25 | 2015-02-18 | 南京华洲药业有限公司 | Mixed herbicide comprising flazasulfuron, dithiopyr and pyributicarb, as well as preparation method of mixed herbicide |
| CN104396990B (en) * | 2014-11-30 | 2017-02-22 | 南京华洲药业有限公司 | Mixed weedicide containing flazasulfuron, dithiopyr and pyributicarb |
-
1993
- 1993-03-22 IT ITMI930547A patent/IT1270985B/en active IP Right Grant
- 1993-03-23 JP JP6435693A patent/JPH0687706A/en active Pending
- 1993-03-23 CN CN 93103348 patent/CN1076585A/en active Pending
- 1993-04-23 TW TW82103143A patent/TW296331B/zh active
-
2001
- 2001-02-28 CN CN 01108964 patent/CN1313035A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0687706A (en) | 1994-03-29 |
| ITMI930547A1 (en) | 1994-09-22 |
| CN1076585A (en) | 1993-09-29 |
| IT1270985B (en) | 1997-05-26 |
| ITMI930547A0 (en) | 1993-03-22 |
| TW296331B (en) | 1997-01-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN1130122C (en) | Herbicidal mixtures | |
| CN1039277C (en) | Herbicide compositions effect matter | |
| CN1084148C (en) | Synergetic herbicidal mixture | |
| CN1041592C (en) | Synergistic composition and method for selective preventing against growth of and removing of weeds | |
| RU2128437C1 (en) | Synergetic herbicide agent, method of weed demolition | |
| CN1303880C (en) | Synergistic weedicide mixture containing cyclohexene ketoxime ether | |
| CN101080173A (en) | Herbicidal compositions | |
| CN1533243A (en) | Synergistic herbicida agent comprising benzoylcyclo hexanediones for application in rice cultivation | |
| CN101080172A (en) | Herbicidal composition | |
| CN1968604A (en) | Herbicidal composition | |
| EA015804B1 (en) | Synergistically active herbicidal agents that are compatible with cultivated plants and contain herbicides from the group of benzoylpyrazoles | |
| CN105682463B (en) | Synergistic herbicide compositions | |
| CN1078852A (en) | The weed killer herbicide of control weeds in paddy field | |
| RU2266647C2 (en) | Herbicidal agent, method for production the same and method for controlling of adverse plants | |
| CN1274223C (en) | Herbicidal agent | |
| CN1589099A (en) | Synergistic herbicidal compositions containing herbicides from the group of benzoylpyrazoles | |
| CN1099220A (en) | A plant-microbicidal composition having synergistic action, comprising at least two active ingredient components, eherein...... | |
| CN1313035A (en) | Herbicidal composition and use thereof | |
| CN1218637C (en) | Insecticide-disinfectant composition containing zarilamid | |
| CN1038466C (en) | Rice field herbcide composition | |
| CN1527667A (en) | Synergistic herbicide comprising benzoylcyclohexane diones for application in rice cultivation | |
| CN1077449A (en) | 2-benzoyl group cyclohexanedione salt selective herbicide, its method for making and the application in weeding | |
| CN102258024A (en) | Herbicide composition | |
| CN1046183C (en) | Synergistic herbicide | |
| CN1056395A (en) | Comprise 2-chloro-6-nitro-3-phenoxybenzamine and be selected from Brominal or ioxynil or a kind of their Herbicidal combinations of at least a weed killer herbicide of derivative |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C06 | Publication | ||
| PB01 | Publication | ||
| C12 | Rejection of a patent application after its publication | ||
| RJ01 | Rejection of invention patent application after publication |