CN1304735A - Medicine for curing chronic colitis - Google Patents
Medicine for curing chronic colitis Download PDFInfo
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- CN1304735A CN1304735A CN 00116023 CN00116023A CN1304735A CN 1304735 A CN1304735 A CN 1304735A CN 00116023 CN00116023 CN 00116023 CN 00116023 A CN00116023 A CN 00116023A CN 1304735 A CN1304735 A CN 1304735A
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Abstract
A Chinese medicine for treating diarrhea, chronic colitis, habitual constipation, etc. is prepared from 18 Chinese-medicinal materials including rhubarb, white atractylodes rhizome, ledebouriella root, cinammon twigs, etc. Its advantaegs include high effective rate up to 100% for diarrhea, and high curative effect for others.
Description
The present invention relates to a kind of medicine, particularly relate to a kind of medicine for the treatment of chronic colitis.
Existing treatment chronic colitis does not also have a kind of comparatively ideal medicine, and adopts berberine usually, but curative effect is relatively poor.
The object of the present invention is to provide a kind ofly has analgesia, spasmolytic, antidiarrheal, antiinflammatory, bacteriostasis, and curative effect is better, the medicine of the treatment chronic colitis that has no side effect.
Purpose of the present invention is achieved through the following technical solutions: prescription of the present invention is:
Rhizoma Drynariae 150-180 Radix Et Rhizoma Rhei 20-40
Rhizoma Atractylodis Macrocephalae 50-80 Radix Saposhnikoviae 30-50
Herba Solidaginis 50-80 Ramulus Cinnamomi 30-50
Acalypha australis Linn. 50-80
Medicine of the present invention has kidney and spleen invigorating, clearing heat and expelling damp, regulating QI to relieve pain, removing food stagnancy blood stasis dispelling, the effect of antiinflammatory bacteriostatic, to six types have loose bowels, chronic colitis, cureless chronic diarrhea all have curative effect preferably, in addition, it also have treatment habitual constipation and gastric abscess etc. to effect, and curative effect is splendid.Medicine of the present invention reaches more than 95% the total effective rate of chronic diarrhea, and after the week of taking medicine, most stomachache, diarrhoea promptly disappear, and it is normal that the feces character is promptly recovered.
In order to make the present invention program clear more complete, be described further below in conjunction with embodiment.
The present invention increases following medicine on the basis of above-mentioned prescription: (unit of weight g)
Radix Codonopsis 50-70 Semen Arecae 50-70
Poria 50-70 Radix Paeoniae Alba 50-70
Semen Coicis 100-130 Radix Linderae 50-70
Pericarpium Citri Reticulatae 50-70 Cortex Magnoliae Officinalis 50-70
Cortex Phellodendri 50-70 Radix Glycyrrhizae 50-70
Rhizoma Alismatis 50-70
The common 18 flavor medicines of forming can improve curative effect of medication of the present invention.
Embodiment 1:
The present invention's prescription is: (unit of weight g)
Rhizoma Drynariae 150 Cortex Phellodendris 50 Radix Paeoniae Alba 50
The Rhizoma Atractylodis Macrocephalae 50 Herba Solidaginiss 50 Radixs Linderae 50
Radix Codonopsis 50 Acalypha australis Linn. 50 Cortex Magnoliae Officinalis 50
Poria 50 Rhizoma Alismatis 50 Radix Saposhnikoviaes 30
Semen Coicis 100 Radix Et Rhizoma Rhei 20 Ramulus Cinnamomi 30
Pericarpium Citri Reticulatae 50 Semen Arecaes 50 Radix Glycyrrhizaes 50
The medicine that is made by the foregoing description 1 prescription is called old intestinal must pacify.
Embodiment 2:
The prescription of this embodiment 2 is: (unit of weight g)
Rhizoma Drynariae 150 Cortex Phellodendris 50 Radix Paeoniae Albas 50
The Rhizoma Atractylodis Macrocephalae 50 Herba Solidaginiss 50 Radixs Linderae 50
Radix Codonopsis 50 Acalypha australis Linn. 50 Cortex Magnoliae Officinalis 50
Poria 5 Rhizoma Alismatis 50 Radix Saposhnikoviaes 30
Semen Coicis 100 Radix Et Rhizoma Rhei 20 Ramulus Cinnamomi 30
Pericarpium Citri Reticulatae 50 Semen Arecaes 50 Radix Glycyrrhizaes 50
Being called new intestinal by the concentrated medicine that makes of the foregoing description 2 prescriptions must pacify.
Below be four parts of clinical reports of Drug therapy chronic diarrhea of the present invention: one, intestinal must be pacified capsule for treating chronic diarrhea 304 routine clinical reports
(1) physical data:
1. sex: in 304 examples, male 218 examples, women 86 examples.Man: woman=3.9: 1.
2. age: minimum 17 years old, maximum 71 years old.Accounted for 66.12% (201/304) in 40～60 years old.
3. the course of disease:＜6 months 101 examples,＞6 months 153 examples,＞1 year 50 example.
(2) case is selected:
1. diagnostic criteria: the standard by " digestive disease " in " International Classification of Diseases " is carried out (1).
2. eliminating study subject: the chronic diarrhea that diseases such as bacillary dysentery, amebic dysentery, tuberculosis of intestine and intestinal canal tumour cause.
3. the case range of choice: 304 routine chronic diarrheal disease kinds distribute and see Table 1.
4. state of an illness weight distributes: according to severe extent, be divided into slightly (long-pending 1 minute), moderate (long-pending 2 minutes), severe (long-pending 3 minutes) in conjunction with cardinal symptom metering integration method.The 304 routine state of an illness distribute as following table 2,3.
(3) Therapeutic Method:
1. capsule composition: the flavor Chinese herbal medicine are refining forms every 0.27 gram with Rhizoma Drynariae, the Rhizoma Atractylodis Macrocephalae etc. 18.
2. medication: each 5, every day 3 times, 6 weeks were a course of treatment.
3. observation index: period in a medicine, fill in cardinal symptom stomachache, diarrhoea, feces character observation table weekly; Check stool for routine, caprophyl cultivation, enteroscopy, barium coloclysis fluoroscopic examination when finishing the course of treatment.
(4) therapeutic outcome:
1. clinical development standard: estimate (2) by " guideline ".
(1) recovery from illness:
1. symptom of diarrhea disappears, and stool every day 1～2 time, is shaped;
2. primary symptom stomachache is most of disappears;
3. relevant with diarrhoea disease objective indicator confirms produce effects;
4. primary symptom stomachache, diarrhoea, feces are shaped three integrations declines more than 80%.
(2) produce effects:
1. times of defecation every day 2～3 times, approximate shaping or loose stool and every day 1 person;
2. primary symptom is improved more than 2 grades;
3. the relevant disease objective determination is near normal;
4. three integrations of primary symptom descend more than 50%.
(3) effective:
1. (1)～(3) index all has improvement in various degree in the produce effects;
2. three integrations of primary symptom descend more than 30%.
(4) invalid: primary symptom does not have improvement or increases the weight of objective determination index no change.
2. therapeutic effect:
(1) total effects: see Table 4
(2) objective determination changes situation before and after the treatment: see Table 6
(3) treatment back primary symptom stomachache, diarrhoea, three integrations of feces character change situation: treatment back stomachache integration descends more than 50%, and diarrhoea, feces character integration descend more than 70%, and three integrations of primary symptom obtain significantly to improve (P＜0.001) before and after the treatment.(5) discuss:
1. square medicine is formed: intestinal must have been pacified capsule main separation kidney and spleen invigorating, the antianaphylactic Rhizoma Drynariae of antidiarrheal, the Rhizoma Atractylodis Macrocephalae and 18 flavor medical materials compositions such as warming middle-Jiao and tonifying deficiency Ramulus Cinnamomi, the Radix Linderae all has curative effect preferably to many types of diarrhoea.Must pacify the capsular test of pesticide effectiveness from intestinal and learn that this medicine has splendid analgesic activity, spasmolysis, anti-diarrhea effect, effects of antiinflammation and bacteriostasis, take medicine a week, most stomachache, diarrhoea promptly disappear, and it is normal that the feces character is promptly recovered.
2 treatment doctor trained in Western medicine chronic diarrheas: generally speaking, the total effective rate that intestinal must be pacified the capsule for treating chronic diarrhea reaches 94.41%.Wherein chronic colitis, large intesitine irritation syndrome effective percentage are slightly high, and inflammatory bowel, infectious colitis effective percentage are lower slightly, but there is no remarkable significant difference (P＞0.05) between the two.Therefore, it is a kind of chronic diarrhea good medicine that multiple doctor trained in Western medicine disease causes that is fit to that intestinal must be pacified capsule, only is with a kind of medicine in the way of going on business, and nearly all diarrhoea can both be controlled.
The 3 treatment traditional Chinese medical science, six types are had loose bowels: having loose bowels can be divided into six types according to " guideline "
(2), promptly cold-dampness type, damp-heat type, dyspepsia type, irritability are taken advantage of spleen type, due to weakness of spleen and stomach, kidney-yang deficiency type.Intestinal must be pacified capsule pure lines Chinese medicine, and six types are had loose bowels all better curative effect, and is slightly good with due to weakness of spleen and stomach, kidney-yang deficiency type, cold-dampness type curative effect, and damp-heat type, irritability take advantage of spleen type, dyspepsia type slightly poor, but also do not have remarkable significant difference (P＞0.05) between two groups.Therefore, from traditional Chinese medical science angle, intestinal must pacify the traditional Chinese medical science six types are had loose bowels all curative effect in various degree, is a kind of good medicine that the multiple pattern of syndrome of the traditional Chinese medical science is had loose bowels that adapts to.In addition, intestinal must pacify capsule also have treatment habitual constipation and gastric abscess etc. to effect, and curative effect is splendid.Two, intestinal must be pacified clinical summary () physical data that capsule for treating is had loose bowels
1。Sex: male 384 examples are organized in treatment, women 136 examples, and men and women's ratio is 3.56: 1.Matched group man 76 examples, women 26 examples, men and women's ratio is 3.92: 1.Two groups suitable (P＞0.05).
2. age: minimum 17 years old of treatment group maximum 92 years old, accounted for 63.84% (309/484) in 40～60 years old.Minimum 16 years old of matched group maximum 72 years old, accounted for 65.69% (67/102) in 40～60 years old.Two groups suitable (P＞0.05).
3. the course of disease: treatment group＜6 month 147 example (30.37%),＞6 months 263 examples (54.34%),＞1 year 79 example (15.29%).Matched group＜6 month 35 example (34.31%),＞6 months 56 examples (54.90%),＞1 year 11 example (10.79%).Two groups suitable (P＞0.05).(2) case is selected
1. diagnostic criteria: diagnose by " guideline " (1) typing standard, stomachache, diarrhoea, feces alteration of form are arranged, the course of disease is more than 1 month, and stool for routine, caprophyl cultivation, intestinal fiberscope or barium enema examination have more than 1 unusual.
2. eliminating study subject: what diseases such as bacillary dysentery, amebic dysentery, tuberculosis of intestine and intestinal canal tumour caused has loose bowels.
3. Chinese medical discrimination typing: see Table 6.
4. by stomachache, diarrhoea, feces form level calibration: see Table 7.
Annotate: above two groups of state of an illness calibration are (P＞0.05) quite.(3) Therapeutic Method
1 treatment group: intestinal must be pacified 5 of capsules, and 3 times on the one, 40 days is a course of treatment.
2 matched groups: Berberine Tablet 3 times on the 0.3rd,, 14 days is a course of treatment.
3 observation index:
(1) period in a medicine is filled in cardinal symptom stomachache, diarrhoea, feces character observation table weekly.
When (2) finish the course of treatment, check stool for routine, caprophyl cultivation, enteroscopy, barium coloclysis fluoroscopic examination.(4) therapeutic outcome: curative effect determinate standard is as follows.
1. fully recover: the transference cure of suffering from abdominal pain, have loose bowels, stool is shaped, and every day 1～2 time, Syndrome in TCM marquis's primary symptom, inferior disease disappear, and tongue fur recovers normally substantially, and is approaching normal with its relevant objective indicator of relevant disease of having loose bowels.
2. produce effects: times of defecation every day 2～3 times, the approximate shaping, or loose stool every day only 1 time, Syndrome in TCM marquis's primary symptom, inferior disease are improved degree (+++→+) more than 2 grades, and relevant objective indicator has clear improvement with having loose bowels.
3. effective: times of defecation and matter, Syndrome in TCM marquis's primary symptom, inferior disease are all taken a favorable turn, and relevant objective indicator take a favorable turn with having loose bowels.
4. invalid: symptom does not have improvement or increases the weight of, and does not all have improvement with the relevant objective indicator of having loose bowels.
Therapeutic outcome sees Table 8～11.(5) discuss:
1. square medicine is formed: in July, 1975 excavation is among the people with Rhizoma Drynariae treatment chronic diarrhea folk prescription, and is on probation really effectively through decoct, is applied to clinical so be pressed into 100,000.To 1980, the osteomiosis sticking patch used up.According to clinical experience, find that it is satisfied inadequately to curative effects such as infectious diarrheas, so researched to developed a compound recipe, be used for clinical with the decoct form.Decoct is used 10 years, makes repeatedly plus-minus and revises, and to ripe typing of nineteen ninety, is refined into intestinal in 1991 and must pacifies capsule.Use 3024 examples through the multicenter hospital clinical, total effective rate reaches 94.97% (2872/3024), and generally reflection is good.
It is composed as follows to write out a prescription: Rhizoma Drynariae, the Rhizoma Atractylodis Macrocephalae, Radix Codonopsis, Poria, the Radix Paeoniae Alba, Ramulus Cinnamomi, Semen Coicis, Rhizoma Alismatis, Pericarpium Citri Reticulatae, Radix Saposhnikoviae, Cortex Magnoliae Officinalis, Semen Arecae, Radix Et Rhizoma Rhei, Cortex Phellodendri, the Radix Linderae, Herba Acalyphae, Herba Solidaginis, Radix Glycyrrhizae are refined into intestinal in accordance with the law and must pacify capsule.
2 pharmacological actions: made the experimentation of a large amount of drug effects, pharmacology, medicineization, toxic and side effects through the institute of materia medica, Fujian Province, proved that intestinal must pacify capsule and have good analgesia, spasmolytic, antidiarrheal, antiinflammatory, bacteriostatic effect.It is a reliable new drug that materials such as the pharmacology of providing, medicine inspection report proof intestinal must be pacified capsule.
3 clinical practices: since excavating Rhizoma Drynariae, so far clinical practice 19 years.Osteomiosis sticking patch and decoct are respectively treated more than patient's 1000 examples, are refined into intestinal in 1991 and must pacify seven hospital application 3024 examples behind the capsule.Verify that through the I phase 484 routine data (matched group 102 examples are used berberine) show total effective rate: cold-dampness type 99.37% (matched group 69.70%), due to weakness of spleen and stomach 100.00% (matched group 58.82%), there were significant differences (P＜0.01～0.02) with matched group.The three days remission rates 53.31% (matched group 30.39%) of suffering from abdominal pain, seven days 98.76% (matched group 67.65%); Diarrhoea antidiarrheal rate three days 75.21% (matched group 39.22%), seven days 99.38% (matched group 63.73%); Feces shaping rate three days 74.17% (matched group 37.25%), seven days 99.38% (matched group 60.78%).Through a large amount of patients reflection, intestinal must be pacified capsule and not only be cured their intractable stomachache, diarrhoea and loose stool, and obstipation is also had good effect, illustrates that intestinal must pacify capsule and have certain two-way function.Three, new and old intestinal must be pacified the clinical efficacy controlled observation of capsule for treating ulcerative colitis
The standard that this paper ulcerative colitis is formulated according to the clinical guidance principle of ulcerative colitis " new Chinese medicine treatment " is made a definite diagnosis, and two groups of sexes, age are close.Old intestinal must peace be organized 30 examples, male 19 examples, women 11 examples, 21～60 years old age, average 37.4 ± 4.5 years old, course of disease half a year～10 year, average 3.5 ± 2.1 years.New intestinal must peace be organized 30 examples, male 17 examples, women 13 examples, 20～60 years old age, average 39.5 ± 5.4 years old, course of disease half a year～11 year, average 4.3 ± 2.3 years.Clinical cardinal symptom has stomachache, diarrhoea or replaces with constipation, and it is shapeless to defecate, and mostly is bloody purulent stool, every day 3～5 times, obstinate, enteroscopy upwards has continuous multiple ground pattern ulcer from rectum, hemogram shows that leukocyte raises, hematochrome reduces, and immunocompetence increases, weight loss.The clinical diseases such as dysentery, tuberculosis of intestine, clone disease, malignant tumor of having got rid of.Doctor trained in Western medicine can be divided into rotten to the corn bleeding type, ulcer type.The traditional Chinese medical science is divided into spleen kidney both deficiency type, damp-heat type.(1) Chinese and western medicine typing:
1 old intestinal must the peace group: 30 examples see Table 12.
2 new intestinal must the peace group: 30 examples see Table 13.(2) doctor trained in Western medicine calibration: see Table 14 (three) primary symptom integrations:
According to the clinical guidance principle of ulcerative colitis " new Chinese medicine treatment ", with metering integrations such as stomachache, bloody purulent stool, times of defecation, straight colonic ulcers, does not promptly have (0 minute), light (1 minute), in (2 minutes), heavy (3 minutes), and statistics is converged comprehensive.
1 old intestinal must the peace group: see Table 15
2 new intestinal must the peace group: see Table 16 (four) treatment data
New and old intestinal must be pacified prescription and is 18 flavor Chinese medicines, and the medication total amount is the same.In the 18 flavor medicines, Rhizoma Drynariae, the Rhizoma Atractylodis Macrocephalae are monarch drug, and other 16 flavor is minister, assistant, messenger drug.New intestinal gets peaceful production. art advanced person, and it is more to extract concentrating part.And that old intestinal must be pacified the pulverizing part is more, so medication dose is bigger.
1. Therapeutic Method:
(1) old intestinal must the peace group: obey 4, every day 3 times, 6 weeks were a course of treatment at every turn.
(2) new intestinal must the peace group: obey 2, every day 3 times, 6 weeks were a course of treatment at every turn.
2. curative effect determinate standard:
(1) recovery from illness: stomachache, bloody purulent stool disappear, and feces is shaped, and times of defecation is normal, straight, colonic ulcer recovery from illness, and the primary symptom integration was reduced to 0 fen.
(2) produce effects: stomachache, bloody purulent stool disappear substantially, and feces still is shaped, and every day, times of defecation was 3～4 times, and rectum, colonic ulcer are almost recovered, and the primary symptom integration was reduced to 0～1 fen.
(3) effective: stomachache, bloody purulent stool alleviate to some extent, and feces is shapeless, and every day, times of defecation was 4～5 times, and colonic ulcer is not fully recovered, and the primary symptom integration was reduced to 1～2 fen.
(4) invalid: symptom does not have improvement or increases the weight of, and the primary symptom integration does not descend.
3. therapeutic outcome:
(1) total effective rate: see Table 17
(2) primary symptom integration decline situation: see Table 18
(3) new and old intestinal must be pacified the change of treatment ulcerative colitis traditional Chinese medical science typing: see Table 19
Its result: old intestinal must peace group 46.66% take a turn for the better, and new intestinal must peace group 63.33% take a turn for the better.
(4) new and old intestinal must be pacified the change of treatment ulcerative colitis doctor trained in Western medicine calibration: see Table 20
Its result: old intestinal must peace group 36.62% change, and new intestinal must peace group 50.00% change.(5) discuss
1. efficacy analysis:
It is relatively poor that this paper must pacify treatment ulcerative colitis curative effect with new and old intestinal.Old intestinal must be pacified and be cured 2 examples, invalid 8 examples, and the primary symptom integration is declined by less than 50.00%, and traditional Chinese medical science typing takes a turn for the better and has only 46.66%, and the change of doctor trained in Western medicine calibration has only 36.62%.New intestinal must the peace group be cured 4 examples, invalid 5 examples, and the primary symptom integration is declined by less than 50.00%, and traditional Chinese medical science typing takes a turn for the better and reaches 63.33%, and the doctor trained in Western medicine calibration changes also less than 50.00%.This shows that new and old intestinal must be pacified the principal agent that should not classify the treatment ulcerative colitis as, use but can be used as accessory drugs.
2. prescription analysis:
It is monarch drug that intestinal must be pacified with Rhizoma Drynariae, the Rhizoma Atractylodis Macrocephalae, and other 16 flavor has the effect of kidney and spleen invigorating, clearing heat and expelling damp, regulating QI to relieve pain, removing food stagnancy blood stasis dispelling for minister, assistant, messenger drug.This new and old intestinal must be pacified capsule 18 flavor Chinese medicine unanimities, and only new intestinal must be pacified the technology advanced person, and concentrating function is better, lacks half so the older intestinal of dosage must be pacified.It is more suitable to be used for the treatment of chronic colitis, and chronic diarrhea is not more had special effect, relatively poor to the ulcerative colitis curative effect.Four, new and old intestinal must be pacified the clinical efficacy controlled observation of capsule for treating chronic colitis
The standard that this group chronic colitis is formulated according to " clinical research of new Chinese medicine treatment chronic colitis is arranged and led principle " is made a definite diagnosis, and sex, two groups of ages are close.Mainly contain chronic colitis disease pathological changes, stomachache is arranged, diarrhoea, Mucous Stool, stool are shapeless, number of times＞3～5 time.The course of disease is more than 6 months.All become thin, symptom such as anemia.Intestinal mirror and stool are cultivated and have got rid of dysentery, schistosomicide, tuberculosis of intestine, inflammatory bowel, tumor etc.Doctor trained in Western medicine can be divided into spasm type, mucus type, anaphylactic type; The traditional Chinese medical science can be divided into cold-dampness type, damp-heat type, the weakness of the spleen and kidney type.(1) Chinese and western medicine typing
1. old intestinal must the peace group: 179 examples.4 of each clothes, see Table 21 at every day 3 times.
2. new intestinal must the peace group: 30 examples.New intestinal must the peace group be that the intestinal of making of adopting new technology must be pacified capsule, and medication dose reduces half than this medicine of old technology, obeys 2 at every turn, every day 3 times, sees Table 22.(2) doctor trained in Western medicine calibration
According to " guideline " two groups of state of an illness calibration are seen Table 23:(three) the primary symptom integration
According to " guideline ", in conjunction with cardinal symptom stomachache, diarrhoea, feces character (mucus shape, pasty state),
Times of defecation (＞3 times/every day) measures integration, promptly note do not have (0 minute), light (1 minute), in (2
Divide), heavy (3 minutes), and statistics is converged and is combined.
1. old intestinal must the peace group: see Table 24.
2. new intestinal must the peace group: see Table 25.(4) treatment data
It is the same that new intestinal must be pacified prescription medication total amount, all is 18 flavor medical materials, is monarch drug with Rhizoma Drynariae, the Rhizoma Atractylodis Macrocephalae, and other 16 flavor is minister, assistant, messenger drug.Be the production technology difference, it is more that old intestinal must be pacified capsule pulverizing part, and it is more that new intestinal must be pacified capsule extraction concentrating part, and therefore, new and old intestinal must be pacified capsule on the dosage curative effect has more different.
1. Therapeutic Method:
(1) old intestinal must the peace group: obey 4,3 times/day, 6 weeks were a course of treatment at every turn.
(2) new intestinal must the peace group: obey 2,3 times/day, 6 weeks were a course of treatment at every turn.2. curative effect determinate standard:
(1) recovery from illness: stomachache, diarrhoea disease disappear, and feces is shaped, every day times of defecation＜2～3 times,
The primary symptom integration reduces to 0.
(2) produce effects: stomachache, diarrhoea disease disappear substantially, and feces still is shaped, every day times of defecation＜3～4
Inferior, the primary symptom integration was reduced to 0～1 fen.
(3) effective: stomachache, diarrhoea disease alleviate to some extent, and feces is shapeless, every day times of defecation＜4～5
Inferior, the primary symptom integration was reduced to 1～2 fen.
(4) invalid: symptom does not have improvement or increases the weight of, and the primary symptom integration does not have decline.
3. therapeutic outcome:
(1) total effective rate: see Table 26
(2) primary symptom integration decline situation: see Table 27-28 primary symptom total mark decline situation: old intestinal must the peace group be more than 81.87%, and new intestinal must the peace group be more than 89.0%.
(3) objective determination improvement situation: see Table 29
(4) Chinese and western medicine pattern of syndrome situation of change before and after the treatment: see Table 30
(5) doctor trained in Western medicine calibration situation of change before and after the treatment: see Table 31 (five) and discuss
1. efficacy analysis:
This paper must pacify the treatment chronic colitis with new and old intestinal and obtain good effect.Old intestinal must peace group effective percentage be 93.85%, and the primary symptom integration descends 81.87%, and the objective determination improvement rate is 86.96～94.87%, and doctor trained in Western medicine disease type improvement rate is 92.03%, and the TCM Syndrome Type improvement rate is 79.67%, and doctor trained in Western medicine calibration improvement rate is 82.3%; New intestinal must peace group effective percentage be 96.67%, and the main symptom integration descends 89.0%, and the objective determination improvement rate is 90.91～96.55%, and doctor trained in Western medicine disease type improvement rate is 96.67%, and the TCM Syndrome Type improvement rate is 90.0%, and doctor trained in Western medicine calibration improvement rate is 96.67%.Above data show that new and old intestinal must be pacified all good result, and it is slightly good to pacify curative effect with the purified new intestinal of new technology especially.
2. prescription analysis:
The monarch drug that intestinal must be pacified is Rhizoma Drynariae, the Rhizoma Atractylodis Macrocephalae, and other 16 flavor medicine is the minister adjuvant.18 flavor medicines useful kidney and strengthening spleens, clearing away heat method are wet, the effect of regulating QI to relieve pain, removing food stagnancy blood stasis dispelling, be used for the treatment of chronic colitis weakness of the spleen and kidney, cold-damp and damp-heat syndrome patient, have special effect, patient's one clothes of not healing are for many years promptly healed, product is sold inside the country to U.S., day, platform, Southeast Asia and all parts of the country, and reputation is rather good.
3. the treatment chronic colitis is known from experience:
Before address, chronic colitis belongs to the traditional Chinese medical science category of having loose bowels.The main symptom of having loose bowels has that stomachache, diarrhoea, feces are shapeless, times of defecation increases, and the primary symptom of chronic colitis to have loose bowels similarly, also have changes such as stool routine examination, feces character, antibacterial culturing, enteroscopy, pathologic finding.It is that the Rhizoma Drynariae and the Rhizoma Atractylodis Macrocephalae, especially Rhizoma Drynariae come among the people the kidney invigorating anti-diarrhea effect to be arranged that intestinal must be pacified the main formula monarch drug, and Compendium of Material Medica spells out that to control " letting out dysentery forever " real rare.1975, we are pressed into 100,000 with the single Rhizoma Drynariae, find on probation that good pain relieving, antidiarrheal are arranged, fall erythrocyte sedimentation rate, fall effects such as anti-" 0 ", antiallergic, but it is slightly poor to cold-dampness type, muggy type diarrhea, so drawn from ancient prescription, Japanese Chinese prescription are clinical that some treatment chronic colitiss, the dampness removing of ulcerative colitis, method are cold, the medicine of antiinflammatory, heat clearing away, tested nearly 15 years the final effective prescription that forms above 18 flavor Chinese crude drugs compositions repeatedly with decoction.We once wished to reduce a few flavor medicines with the side of tearing open experiment, but the result all fails, and curative effect descends significantly.But central Ministry of Public Health is recommended the Golden Horse liver Thailand of treatment hepatitis B, is that make the Zunyi City, Guizhou Province, 38 flavor Chinese medicines is arranged, and special effect is arranged, and it is popular to rescue hepatitis B in Thailand, and four wheat harvesting periods just are very popular hepatitis B and have subdued.Therefore, how many Chinese patent medicines does not lie in flavour of a drug, should select for use practically.
The sick distribution of planting of table 1 304 examples
| The sick kind distributes | The example number | ????％ | |
| Inflammatory bowel | Crohn ' s disease | ????11 | ????3.61 |
| Ulcerative colitis | ????37 | ????12.17 | |
| Chronic colitis | Mucous colitis | ????72 | ????23.68 |
| Spastic colitis | ????77 | ????25.33 | |
| Allergic colitis | ????30 | ????9.87 | |
| Infectious colitis | ????41 | ????13.50 | |
| Large intesitine irritation syndrome | ????36 | ????11.84 | |
| Add up to | ????304 | ????100.0 | |
The table 2 304 routine chronic diarrhea primary symptom tables of integrals
| Integration | Stomachache | Diarrhoea | The feces character | |||
| The example number | ????％ | The example number | ????％ | The example number | ????％ | |
| 0 minute | ???32 | ??10.53 | ????0 | ????0 | ????0 | ????0 |
| 1 minute | ???71 | ??23.35 | ??103 | ??33.88 | ??147 | ??48.36 |
| 2 minutes | ??157 | ??51.64 | ??142 | ??46.71 | ??121 | ??39.80 |
| 3 minutes | ???44 | ??14.48 | ???59 | ??19.41 | ???36 | ??11.84 |
| Add up to | ??304 | ??100.0 | ??304 | ??100.0 | ??304 | ??100.0 |
The table 3 304 routine state of an illness are divided kilsyth basalt
| State of an illness calibration | The example number | ????％ |
| Slightly | ????103 | ????33.88 |
| Moderate | ????142 | ????46.71 |
| Severe | ????59 | ????19.41 |
| Add up to | ????304 | ????100.0 |
Table 4 304 routine total effectses
| Curative effect | The example number | ????％ |
| Recovery from illness | ????91 | ????29.93 |
| Produce effects | ????117 | ????38.49 |
| Effectively | ????79 | ????25.99 |
| Invalid | ????17 | ????5.59 |
| Total effective rate | ????287 | ????94.41 |
Objective determination changes before and after table 5 treatment
| Inspection item | Before the treatment | After the treatment | The P value | ||
| Positive case | ????％ | The case of turning out cloudy | ????％ | ||
| Stool for routine | ????304 | ??100.0 | ????287 | ????94.41 | ??＜0.001 |
| Caprophyl is cultivated | ????41 | ??13.49 | ????41 | ????100.0 | ??＜0.001 |
| Enteroscopy | ????271 | ??89.14 | ????260 | ????95.94 | ??＜0.001 |
| Barium is irritated and is checked | ????33 | ??10.86 | ????27 | ????81.82 | ??＜0.001 |
Table 6 Chinese medical discrimination typing
| The example number | ????％ | |||
| Traditional Chinese medical science typing | The treatment group | Matched group | The treatment group | Matched group |
| Cold-dampness type | ????161 | ????33 | ????33.26 | ????32.35 |
| Due to weakness of spleen and stomach | ????164 | ????35 | ????33.88 | ????34.31 |
| Kidney-yang deficiency type | ????159 | ????34 | ????32.86 | ????33.34 |
| Add up to | ????484 | ????102 | ????100.00 | ????100.00 |
Table 7 state of an illness weight calibration
| The example number | ????％ | |||
| Calibration | The treatment group | Matched group | The treatment group | Matched group |
| Slightly | ????203 | ????39 | ????41.94 | ????38.24 |
| Moderate | ????247 | ????51 | ????51.03 | ????50.00 |
| Severe | ????34 | ????12 | ????7.03 | ????11.76 |
| Add up to | ????484 | ????102 | ??100.00 | ????100.00 |
Table 8 intestinal must be pacified capsule for treating group total effects
| Cold-dampness type | Due to weakness of spleen and stomach | Kidney-yang deficiency type | ||||
| Curative effect | The example number | ??％ | The example number | ????％ | The example number | ????％ |
| Recovery from illness | ????45 | ??27.95 | ???48 | ????29.26 | ????39 | ??24.53 |
| Produce effects | ????58 | ??36.02 | ???61 | ????37.20 | ????53 | ??33.33 |
| Effectively | ????56 | ??34.78 | ???55 | ????33.54 | ????63 | ??39.62 |
| Invalid | ????1 | ??0.62 | ????0 | ????0 | ????2 | ??1.26 |
| Add up to | ???159 | ??99.37 | ??164 | ???100.00 | ????155 | ??98.74 |
Annotate: above treatment group total effective rate 99.38% (478/481), effective percentage does not have significant difference (P＞0.05) between three types.
Table 9 Berberine Tablet matched group total effects
| Cold-dampness type | Due to weakness of spleen and stomach | Kidney-yang deficiency type | ||||
| Curative effect | The example number | ??％ | The example number | ????％ | The example number | ????％ |
| Recovery from illness | ????5 | ??15.16 | ????4 | ????11.43 | ????3 | ??8.82 |
| Produce effects | ????11 | ??33.33 | ????10 | ????28.57 | ????7 | ??20.59 |
| Effectively | ????7 | ??21.21 | ????10 | ????28.57 | ????10 | ??29.41 |
| Invalid | ????10 | ??30.30 | ????11 | ????31.43 | ????14 | ??41.18 |
| Add up to | ????23 | ??69.70 | ????24 | ????68.57 | ????20 | ??58.82 |
Annotate: above matched group total effective rate 65.69% (67/102), there were significant differences (P＜0.02) with the treatment group, but zero difference (P＞0.05) between the matched group.
Table 10 stomachache, diarrhoea, feces shapeliness rate of rotation are relatively
| The treatment group | Matched group | |||||||
| Three days | Seven days | Three days | Seven days | |||||
| The example number | ????％ | The example number | ????％ | The example number | ????％ | The example number | ????％ | |
| The stomachache remission rate | 258 | ?53.31 | ??478 | 98.76 | ??31 | ?30.39 | ?69 | ?67.65 |
| Diarrhoea antidiarrheal rate | 364 | ?75.21 | ??481 | 99.38 | ??40 | ?39.22 | ?65 | ?63.73 |
| The feces shaping rate | 359 | ?74.17 | ??481 | 99.38 | ??38 | ?37.25 | ?62 | ?60.78 |
| Three average improvement rates of symptom | 327 | ?67.56 | ??480 | 99.17 | ??36 | ?35.29 | ?65 | ?63.37 |
Annotate: there were significant differences (P＜0.01) for the improvement rate of treatment group and three primary symptoms of matched group, and individual event symptom improvement rate also has notable difference (P＜0.010.02).
Check that negative conversion rate relatively for four before and after table 11 treatment
Annotate: there were significant differences (P＜0.01) for the negative conversion rate of treatment group and four inspections of matched group, and the individual check negative conversion rate also has notable difference (P＜0.01～0.02).
| The treatment group | Matched group | |||||||
| Before the treatment | After the treatment | Before the treatment | After the treatment | |||||
| Positive | ????％ | Turn out cloudy | ????％ | Positive | ??％ | Turn out cloudy | ????％ | |
| Stool for routine | ??484 | ?100.00 | ?481 | 99.38 | ??102 | 100.00 | ????74 | ????72.55 |
| Caprophyl is cultivated | ???72 | ??14.88 | ??72 | 100.00 | ???34 | ?33.33 | ????21 | ????61.76 |
| Enteroscopy | ??398 | ??82.23 | ??389 | 97.74 | ???93 | ?91.18 | ????69 | ????74.19 |
| Barium is irritated and is checked | ??143 | ??29.55 | ??131 | 91.61 | ???29 | ?28.43 | ????16 | ????55.17 |
| Average negative conversion rate | ????97.18％ | ?65.92％ | ||||||
The old intestinal of table 12 must peace group Chinese and western medicine typing
| The doctor trained in Western medicine typing | Traditional Chinese medical science typing | ||||
| Rotten to the corn bleeding type | 13 examples | 43.33％ | Spleen kidney both deficiency type | 14 examples | ??46.67％ |
| The ulcer type | 17 examples | 56.67％ | Damp-heat type | 16 examples | ??53.33％ |
| Add up to | 30 examples | 100％ | 30 examples | ??100％ | |
The new intestinal of table 13 must peace group Chinese and western medicine typing
| The doctor trained in Western medicine typing | Traditional Chinese medical science typing | ||||
| Rotten to the corn bleeding type | 16 examples | ??53.33％ | Spleen kidney both deficiency type | 15 examples | ??50.00％ |
| The ulcer type | 14 examples | ??46.67％ | Damp-heat type | 15 examples | ??50.00％ |
| Add up to | 30 examples | ??100％ | 30 examples | ??100％ | |
The new and old intestinal of table 14 must be pacified the ulcerative colitis calibration
| Calibration | Old intestinal must the peace group | New intestinal must the peace group | ||
| Slightly | 10 examples | ??33.33％ | 10 examples | ??33.33％ |
| Moderate | 10 examples | ??33.33％ | 10 examples | ??33.33％ |
| Severe | 10 examples | ??33.34％ | 10 examples | ??33.34％ |
| Add up to | 30 examples | ??100％ | 30 examples | ??100％ |
The old intestinal of table 15 must the remittance of peace group primary symptom integration be combined (%)
| Integration | Stomachache | Bloody purulent stool | Times of defecation | Intestinal ulcer | ||||
| 0 minute | 6 examples | ??20.00 | 9 examples | ??30.00 | 7 examples | ??23.33 | 4 examples | ??13.33 |
| 1 minute | 5 examples | ??16.67 | 4 examples | ??13.33 | 8 examples | ??26.67 | 4 examples | ??13.33 |
| 2 minutes | 8 examples | ??26.66 | 7 examples | ??23.33 | 5 examples | ??16.67 | 5 examples | ??16.67 |
| 3 minutes | 11 examples | ??36.67 | 10 examples | ??33.34 | 10 examples | ??33.33 | 17 examples | ??56.67 |
| Add up to | 30 examples | ??100.0 | 30 examples | ??100.0 | 30 examples | ??100.0 | 30 examples | ??100.0 |
The new intestinal of table 16 must the remittance of peace group primary symptom integration be combined (%)
| Integration | Stomachache | Bloody purulent stool | Times of defecation | Intestinal ulcer | ||||
| 0 minute | 5 examples | ??16.67 | 7 examples | ??23.33 | 6 examples | ??20.00 | 5 examples | ??16.67 |
| 1 minute | 8 examples | ??26.67 | 6 examples | ??20.00 | 7 examples | ??23.33 | 5 examples | ??16.67 |
| 2 minutes | 7 examples | ??23.33 | 6 examples | ??20.00 | 7 examples | ??23.34 | 6 examples | ??20.00 |
| 3 minutes | 10 examples | ??33.33 | 11 examples | ??36.67 | 10 examples | ??33.33 | 14 examples | ??46.66 |
| Add up to | 30 examples | ??100.0 | 30 examples | ??100.0 | 30 examples | ??100.0 | 30 examples | ??100.0 |
The new and old intestinal of table 17 must be pacified treatment ulcerative colitis contrast (%)
| The result | Old intestinal must be pacified | New intestinal must the peace group | ||
| Recovery from illness | 2 examples | ????6.7 | 4 examples | ????13.33 |
| Produce effects | 8 examples | ???26.7 | 10 examples | ????33.33 |
| Effectively | 12 examples | ???40.0 | 11 examples | ????36.67 |
| Invalid | 8 examples | ???26.7 | 5 examples | ????16.67 |
| Add up to | 30 examples | ??100.0 | 30 examples | ???100.0 |
| Total effective rate | ????73.4 | ????83.33 | ||
The new intestinal of table 18 must peace group treatment ulcerative colitis reduce the primary symptom integration
| Integration | Stomachache | Bloody purulent stool | Times of defecation | Intestinal ulcer |
| 0 minute | 5 examples → 9 examples | 7 examples → 13 examples | 6 examples → 15 examples | 5 examples → 12 examples |
| 1 minute | 8 examples → 11 examples | 6 examples → 7 examples | 7 examples → 6 examples | 5 examples → 7 examples |
| 2 minutes | 7 examples → 5 examples | 6 examples → 5 examples | 7 examples → 4 examples | 6 examples → 6 examples |
| 3 minutes | 10 examples → 5 examples | 11 examples → 5 examples | 10 examples → 5 examples | 14 examples → 5 examples |
| Primary symptom decline integration | ????14.29％ | ????37.25％ | ????43.14％ | ????42.37％ |
The new and old intestinal of table 19 must change by peace group treatment ulcerative colitis traditional Chinese medical science typing
| Traditional Chinese medical science typing | Old intestinal must the peace group | New intestinal must the peace group |
| Spleen kidney both deficiency type | ??46.67％→36.67％ | ????50.0％→20.0％ |
| Damp-heat type | ??53.33％→16.67％ | ????50.0％→16.67％ |
The new and old intestinal of table 20 must change by peace group treatment ulcerative colitis doctor trained in Western medicine calibration
| The doctor trained in Western medicine calibration | Old intestinal must the peace group | New intestinal must the peace group |
| Slightly | ??33.33％→16.67％ | ??33.33％→13.33％ |
| Moderate | ??33.33％→20.00％ | ??33.33％→20.00％ |
| Severe | ??33.33％→26.70％ | ??33.33％→16.67％ |
The old intestinal of table 21 must peace group chronic colitis typing
| The doctor trained in Western medicine typing | Traditional Chinese medical science typing | ||||
| Spasm type | 77 examples | ??43.01％ | Cold-dampness type | 34 examples | ??19.00％ |
| The mucus type | 72 examples | ??40.22％ | Damp-heat type | 64 examples | ??35.75％ |
| Anaphylactic type | 30 examples | ??15.77％ | The weakness of the spleen and kidney type | 81 examples | ??45.25％ |
| Amount to | 179 examples | ??100％ | Amount to | 179 examples | ??100％ |
The new intestinal of table 22 must peace group chronic colitis typing
| The doctor trained in Western medicine typing | Traditional Chinese medical science typing | ||||
| Spasm type | 11 examples | ??36.67％ | Cold-dampness type | 6 examples | ??20.00％ |
| The mucus type | 10 examples | ??33.33％ | Damp-heat type | 10 examples | ??33.33％ |
| Anaphylactic type | 9 examples | ??30.00％ | The weakness of the spleen and kidney type | 14 examples | ??46.67％ |
| Amount to | 30 examples | ??100％ | Amount to | 30 examples | ????100％ |
The new intestinal of table 23 must peace group chronic colitis state of an illness calibration
| Old intestinal must the peace group | New intestinal must the peace group | ||||
| Slightly | 68 examples | ??37.99％ | Slightly | 10 examples | ??33.34％ |
| Moderate | 87 examples | ??48.60％ | Moderate | 16 examples | ??53.33％ |
| Severe | 24 examples | ??13.41％ | Severe | 4 examples | ??13.33％ |
| Amount to | 179 examples | ??100％ | Amount to | 30 examples | ????100％ |
The old intestinal of table 24 must the remittance of peace group primary symptom integral distribution be combined (%)
| Calibration | Stomachache | Diarrhoea | The feces character | Times of defecation | ||||
| 0 minute | 41 examples | 22.91 | 18 examples | 10.06 | 23 examples | 12.85 | 33 examples | 18.44 |
| 1 minute | 36 examples | 20.11 | 44 examples | 24.58 | 72 examples | 40.22 | 65 examples | 36.31 |
| 2 minutes | 72 examples | 40.22 | 89 examples | 49.72 | 59 examples | 32.96 | 62 examples | 34.64 |
| 3 minutes | 30 examples | 16.76 | 28 examples | 15.64 | 25 examples | 13.97 | 19 examples | 10.61 |
| Amount to | 179 examples | 100.0 | 179 examples | 100.0 | 179 examples | 100.0 | 179 examples | 100.0 |
The new intestinal of table 25 must the remittance of peace group primary symptom integral distribution be combined (%)
| Calibration | Stomachache | Diarrhoea | The feces character | Times of defecation | ||||
| 0 minute | 2 examples | ??6.67 | 0 example | ????0.0 | 0 example | ????0.0 | 0 example | ??0.0 |
| 1 minute | 10 examples | ??33.33 | 11 examples | ??36.67 | 9 examples | ???30.0 | 10 examples | ??33.33 |
| 2 minutes | 16 examples | ??53.33 | 15 examples | ??50.0 | 18 examples | ???60.0 | 15 examples | ??50.0 |
| 3 minutes | 2 examples | ??6.67 | 4 examples | ??13.33 | 3 examples | ???10.0 | 5 examples | ??16.67 |
| Amount to | 30 examples | ??100.0 | 30 examples | ??100.0 | 30 examples | ??100.0 | 30 examples | ??100.0 |
The new and old intestinal of table 26 must be pacified the contrast of treatment chronic colitis
| Old intestinal must the peace group | New intestinal must the peace group | ||||
| Recovery from illness | 45 examples | 25.14％ | Recovery from illness | 9 examples | ??30.0％ |
| Produce effects | 57 examples | 31.84％ | Produce effects | 12 examples | ??40.0％ |
| Effectively | 66 examples | 36.87％ | Effectively | 8 examples | ??26.67％ |
| Invalid | 11 examples | ?6.15％ | Invalid | 1 example | ???3.33％ |
| Amount to | 179 examples | 100.0％ | Amount to | 30 examples | ??100.0％ |
| Total effective rate | Old intestinal must be pacified | Group is 93.85% | New intestinal must the peace group be 96.67% | ||
The old intestinal of table 27 must peace group treatment chronic colitis reduce the primary symptom integration
| Calibration | Stomachache | Diarrhoea | The feces character | Times of defecation |
| 0 minute | 41 examples → 162 examples | 18 examples → 44 examples | 23 examples → 161 examples | 33 examples → 156 examples |
| 1 minute | 36 examples → 3 examples | 44 examples → 4 examples | 72 examples → 3 examples | 65 examples → 4 examples |
| 2 minutes | 72 examples → 5 examples | 89 examples → 6 examples | 59 examples → 5 examples | 62 examples → 7 examples |
| 3 minutes | 30 examples → 9 examples | 28 examples → 11 examples | 25 examples → 10 examples | 19 examples → 12 examples |
| The primary symptom integration descends | ????87.68％ | ????81.87％ | ????88.46％ | ????84.25％ |
The new intestinal of table 28 must peace group treatment chronic colitis reduce the primary symptom integration
| Calibration | Stomachache | Diarrhoea | The feces character | Times of defecation |
| 0 minute | 2 examples → 28 examples | 0 example → 29 examples | 0 example → 27 examples | 0 example → 28 examples |
| 1 minute | 10 examples → 0 example | 11 examples → 0 example | 9 examples → 3 examples | 10 examples → 2 examples |
| 2 minutes | 16 examples → 1 example | 15 examples → 0 example | 18 examples → 0 example | 15 examples → 0 example |
| 3 minutes | 2 examples → 1 example | 4 examples → 1 example | 3 examples → 0 example | 5 examples → 0 example |
| The primary symptom integration descends | ????92.86％ | ????96.67％ | ????89.0％ | ????93.33％ |
The new and old intestinal of table 29 must be pacified the treatment chronic colitis objective determination situation of turning out cloudy
| Group | Time | Stool for routine | Caprophyl is cultivated | The intestinal mirror | Pathologic finding | ||||
| Old intestinal must the peace group | Before controlling | Positive | 161 examples | Positive | 58 examples | Positive | 156 examples | Positive | 123 examples |
| After controlling | Turn out cloudy | 140 examples | Turn out cloudy | 51 examples | Turn out cloudy | 148 examples | Turn out cloudy | 111 examples | |
| New intestinal must the peace group | Before controlling | Positive | 29 examples | Positive | 11 examples | Positive | 27 examples | Positive | 19 examples |
| After controlling | Turn out cloudy | 28 examples | Turn out cloudy | 10 examples | Turn out cloudy | 26 examples | Turn out cloudy | 18 examples | |
| Negative conversion rate | Old intestinal must the peace group be 86.96%～94.87%, and new intestinal must the peace group be 90.91%～96.55% | ||||||||
The new and old intestinal of table 30 must change by peace group treatment front and back doctor trained in Western medicine typing
| The doctor trained in Western medicine pattern of syndrome | Old intestinal must the peace group | New intestinal must the peace group |
| Spasm type | ????43.01％→3.8％ | ????36.67％→0.0 |
| The mucus type | ????40.22％→4.17％ | ????33.33％→3.33％ |
| Anaphylactic type | ????15.77％→0.0 | ????30.00％→0.0 |
| Old intestinal must peace group 92.03% obtain taking a turn for the better, and new intestinal must peace group 96.0% obtain taking a turn for the better | ||
The new and old intestinal of table 31 must change by peace group treatment front and back traditional Chinese medical science typing
| TCM Syndrome Type | Old intestinal must the peace group | New intestinal must the peace group |
| Cold-dampness type | ????19.00％→8.82％ | ????20.0％→0.0 |
| Damp-heat type | ????35.75％→7.81％ | ????33.33％→10.0％ |
| The weakness of the spleen and kidney type | ????45.25％→3.7％ | ????46.67％→0.0 |
| Old intestinal must peace group 79.67% obtain taking a turn for the better, and new intestinal must peace group 90.0% obtain taking a turn for the better | ||
The new and old intestinal of table 32 must change by peace group treatment front and back doctor trained in Western medicine calibration
| Calibration | Old intestinal must the peace group | New intestinal must the peace group |
| Slightly | ????37.99％→8.82％ | ????33.34％→0.0 |
| Moderate | ????48.60％→3.55％ | ????53.33％→0.0 |
| Severe | ????13.41％→8.33％ | ????13.33％→3.33％ |
| Old intestinal must peace group 82.3% obtain taking a turn for the better, and new intestinal must peace group 96.67% obtain taking a turn for the better | ||
List of references (1) WHO Collaborating Center for Classification of Diseases, Beijing: digestive disease.International Classification of Diseases (first volume), People's Health Publisher, 376～380 pages of front pages, 1984.(2) bureau of drug administration of Ministry of Health of the People's Republic of China: the clinical research guideline (second batch) that new drug (Chinese medicine) treatment is had loose bowels, the 51st～54 page, 1988.
Claims (2)
1. medicine for the treatment of chronic colitis, it is characterized in that: it is made up of following prescription: the g of unit
Rhizoma Drynariae 150-180 Radix Et Rhizoma Rhei 20-40
Rhizoma Atractylodis Macrocephalae 50-80 Radix Saposhnikoviae 30-50
Herba Solidaginis 50-80 Ramulus Cinnamomi 30-50
Acalypha australis Linn. 50-80
2. a kind of medicine for the treatment of chronic colitis according to claim 1 is characterized in that: it also by
Radix Codonopsis 50-70 Semen Arecae 50-70
Poria 50-70 Radix Paeoniae Alba 50-70
Semen Coicis 100-130 Radix Linderae 50-70
Pericarpium Citri Reticulatae 50-70 Cortex Magnoliae Officinalis 50-70
Cortex Phellodendri 50-70 Radix Glycyrrhizae 50-70
Rhizoma Alismatis 50-70
The common 18 flavor medicines of forming.
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| CN 00116023 CN1203872C (en) | 2000-09-06 | 2000-09-06 | Medicine for curing chronic colitis |
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| CN 00116023 CN1203872C (en) | 2000-09-06 | 2000-09-06 | Medicine for curing chronic colitis |
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| CN1203872C CN1203872C (en) | 2005-06-01 |
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| CN1305499C (en) * | 2005-10-26 | 2007-03-21 | 柴伟利 | Medicine for treating chronic constipation |
| CN100339103C (en) * | 2005-08-01 | 2007-09-26 | 颜怀玮 | Medicine, food used article for preventing and curing acute or chronic diarrhoea and method for producing the same |
| CN100339104C (en) * | 2005-08-01 | 2007-09-26 | 颜怀玮 | Medicine, food used article for preventing and curing enteritis and method for producing the same |
| CN100339105C (en) * | 2005-08-01 | 2007-09-26 | 颜怀玮 | Medicine, food used article for preventing and curing acute or chronic enteritis and method for producing the same |
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| CN100339103C (en) * | 2005-08-01 | 2007-09-26 | 颜怀玮 | Medicine, food used article for preventing and curing acute or chronic diarrhoea and method for producing the same |
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| CN100339105C (en) * | 2005-08-01 | 2007-09-26 | 颜怀玮 | Medicine, food used article for preventing and curing acute or chronic enteritis and method for producing the same |
| CN100342893C (en) * | 2005-08-01 | 2007-10-17 | 颜怀玮 | Medicine, food used article for preventing and curing acute diarrhoea and method for producing the same |
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| CN100434100C (en) * | 2005-08-01 | 2008-11-19 | 颜怀玮 | Medicine, food used article for preventing and curing chronic diarrhoea and method for producing the same |
| CN1305499C (en) * | 2005-10-26 | 2007-03-21 | 柴伟利 | Medicine for treating chronic constipation |
| CN101537146B (en) * | 2008-03-19 | 2011-01-12 | 北京绿源求证科技发展有限责任公司 | Chinese medicine for treating carcinoma of colon |
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| CN102258720B (en) * | 2011-07-08 | 2012-07-25 | 韩喜 | Traditional Chinese medicine for treating colitis |
| CN103784848A (en) * | 2014-01-15 | 2014-05-14 | 中国人民解放军第二军医大学 | Traditional Chinese medicinal composition for treating chronic colitis and preparation and application thereof |
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