CN1299650A

CN1299650A - Oral capsule and paster for treating ischemic femur head necrosis and their preparation

Info

Publication number: CN1299650A
Application number: CN 00101262
Authority: CN
Inventors: 吴永福; 吴道峰; 吴春玲
Original assignee: 吴永福
Priority date: 2000-01-25
Filing date: 2000-01-25
Publication date: 2001-06-20

Abstract

The present invention discloses an oral capsule and an adhesive plaster preparation for curing ischemic necrosis of femoral head and their preparation method. The oral capsule is made up by 24 pure Chinese medicinal materials of Chinese angelica root, frankincense, carthamus flower, dragon's blood, ephedra, dipsacus root, chaenomeles fruit and others, and the adhesive plaster is made up by using 33 Chinese medicinal materials of aconite main tuber, wild aconite tuber, dipsaucus root, nototerygium root, peach kernel and others, and adding proper quantity of minium and sesame oil through a certain preparation process. Its effective rate is 100% and curative rate is 85.2%.

Description

Oral capsule and the plaster preparation and the preparation method of treatment ischemic necrosis of femoral head

The present invention is oral capsule and the plaster preparation and the preparation method of treatment ischemic necrosis of femoral head, belongs to field of pharmaceutical technology.

Ischemic necrosis of femoral head is the orthopedics department difficult disease, and its sickness rate day by day increases, and at present, doctor trained in Western medicine overweights operative treatment to this patient-side both at home and abroad, because the selection of operative indication is subjected to certain limitation, late result is also unsatisfactory; Particularly centering, adolescence use the primary disease that hormone brought out, and more feel a delicacy about.

The objective of the invention is: the treatment pure extract oral capsule preparations of ischemic necrosis of femoral head and externally applied plaster and preparation method thereof are provided, this oral capsule preparation, externally applied plaster can be removed the hardship of ischemic necrosis of femoral head patient's operation, good effect, short treating period, healing be fast, do not recur after controlling, have no side effect, easy to use, be beneficial to and apply, special centering adolescence, since the ischemic head necrosis disease of using hormone to bring out, more remarkable treatment effect.

The present invention treats the pure extract oral capsule preparations of ischemic necrosis of femoral head, is formed by 24 kinds of prepared from traditional Chinese medicines, and said preparation Main Ingredients and Appearance and shared this for example descend:

Radix Angelicae Sinensis 12.8%-13.1% Olibanum 5.1%-5.15%

Flos Carthami 1.25%-1.3% Sanguis Draxonis 12.5%-13.0%

Herba Ephedrae 7.65%-7.7% Radix Dipsaci 7.66%-7.7%

Fructus Chaenomelis 1.25%-1.3% Semen Cucumidis sativi 7.6%-7.7%

Catechu 2.5%-2.6% Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 2.5%-2.6%

Radix Saposhnikoviae 1.25%-1.3% Myrrha 3.8%-3.9%

The Radix Stephaniae Tetrandrae 2.5%-2.6% river 2.5%-2.6% of Qiang

Cattle sunset 3.8%-3.9% drynaria baronii 1.2%-1.3%

Radix Aconiti 1.25%-1.3% Radix Aconiti Kusnezoffii 1.2%-1.3%

The yellow 3.8%-3.9% eupolyphage sece steleophaga of Zhu 3.8%-3.9%

Radix Et Rhizoma Rhei 3.8%-3.9% Pyritum 3.8%-3.9%

Fructus Forsythiae 3.8%-3.9% Borneolum Syntheticum 1.2%-1.3%

The preparation method of this oral capsule preparation is:

Each component is dried respectively in ratio separately, and mix metering back respectively, is ground into 120 orders, and being mixed then incapsulates, and dress 0.45g in every capsule is standby by the false proof bottle capping of packing into of a fixing grain number.

The Dressed plaster of treatment ischemic necrosis of femoral head is formed by 33 kinds of Chinese medicines and Plumbum preparatium, Oleum Sesami, the process of preparing Chinese medicine, and the Main Ingredients and Appearance of this plaster and contained ratio are as follows:

Radix Aconiti 2.5%-2.7% Radix Aconiti Kusnezoffii 2.5%-2.7%

Radix Dipsaci 2.5%-2.7% Rhizoma Et Radix Notopterygii 2.5%-2.7%

Semen Persicae 2.5%-2.7% Radix Clematidis 2.5%-2.7%

Sea maple rattan 2.5%-2.7% Bombyx Batryticatus 2.5%-2.7%

Flos Lonicerae 2.5%-2.7% Rhizoma Alpiniae Officinarum 2.5%-2.7%

Radix Glycyrrhizae 2.5%-2.7% cattle sunset 2.5%-2.7%

Fructus Tribuli 2.5%-2.7% Cortex Eucommiae 2.5%-2.7%

Thin He 2.5%-2.7% Rhizoma Cimicifugae 2.5%-2.7%

Radix Saposhnikoviae 2.5%-2.7% Radix Angelicae Sinensis 2.82%-2.85%

Fructus Forsythiae 2.5%-2.7% Radix Angelicae Pubescentis 2.5%-2.7%

Herba Taxilli 1%-1.1% Flos Carthami 5.2%-5.3%

Rhizoma Gastrodiae 5.2%-5.3% Herba Lycopodii 10.4%-5.45%

Herba speranskiae tuberculatae 10.4%-10.45% moxibustion Pyritum 7.8%-7.85%

Moschus 0.3%-0.31% Borneolum Syntheticum 0.5%-0.53%

Cortex Cinnamomi 2.6%-2.62% Flos Caryophylli 2.6%-2.62%

Sanguis Draxonis 0.5%-0.53% Olibanum 0.51%-0.53%

Myrrha 0.5%-0.53%

Plumbum preparatium is an amount of, Oleum Sesami is an amount of.

The preparation method of this plaster is: at first with Moschus, Borneolum Syntheticum, Cortex Cinnamomi, Flos Caryophylli, Sanguis Draxonis, Olibanum, seven kinds of medicines of Myrrha, pulverizing in proportion is that 120 order smalls are deposited; Other 26 kinds of Chinese medicines are dropped in the Oleum Sesami in proportion soaked 36 hours, it serves as an amount of that the ratio of Oleum Sesami and 26 kinds of medicines can be soaked whole Chinese medicines with Oleum Sesami, with slow fire with the medicine that soaks fried be sallow to the medicine complexion changed, can not explode blackly, it is clean to pull filter then out, remaining Oleum Sesami is measured, carry out compatibility in the ratio of every jin, a traditional unit of weight of Oleum Sesami and 250g Plumbum preparatium again and concoct, must under slow fire, slowly concoct during the process of preparing Chinese medicine, and the twist that does not stop, when Plumbum preparatium is twisted in Oleum Sesami mix evenly after, could be from fire.Behind fire,, washed 96 hours, or soaked 120 hours with cold water with running water with the Plumbum preparatium and the Oleum Sesami cream that prepare, changed water once in per 8 hours, and it was reheated seven kinds of medicamental pulverata will pulverizing earlier after the fusing at last again and be blended into, strand is even, spread out on cloth or oilpaper, be plaster, can come into operation.

Advantage of the present invention is: have tangible promotion sequestrum to draw, new osteanagenesis effect increases blood capillary quantity and bone density, its instant effect, and curative effect of medication is reliable, and cure rate is 85.2%, and effective percentage is 100%.

Now lift preferable embodiment and use the process of this treatment by Chinese herbs ischemic necrosis of femoral head disease and usage, consumption to be described in detail as follows:

The preparation method of the oral Chinese medicine of treatment ischemic necrosis of femoral head is:

Following 24 kinds of Chinese medicines are dried respectively, and mix metering back respectively, is ground into 120 orders, and being mixed then incapsulates, dress 0.45g in every capsule, and standby by the capping of packing in the imitative pseudo-bottle of a fixing grain number, the weight of these 24 kinds of Chinese medicines is respectively:

Radix Angelicae Sinensis 130 g Olibanums 51 g

Flos Carthami 12.5 g Sanguis Draxonis 125 g

Herba Ephedrae 76.5 g Radix Dipsaci 76 g

Fructus Chaenomelis 12.5 g Semen Cucumidis sativi 88 g

Catechu 25 g Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 25 g

Radix Saposhnikoviae 13 g Myrrhas 38 g

25 g of Radix Stephaniae Tetrandrae 25 g river Qiang

Cattle sunset 38 g drynaria baroniis, 13 g

Radix Aconiti 12.5 g Radix Aconiti Kusnezoffii 12 g

Yellow 38 g eupolyphage sece steleophagas, 38 g of Zhu

Radix Et Rhizoma Rhei 38 g Pyritums 38 g

Fructus Forsythiae 38 g Borneolum Syntheticums 17 g

Amount to: 1,000g

The preparation method of treatment ischemic necrosis of femoral head Dressed plaster is: following 33 kinds of Chinese medicines and an amount of Plumbum preparatium, Oleum Sesami are concocted and formed: the quantity of these 33 kinds of Chinese medicines is respectively:

Radix Aconiti 26 g Radix Aconiti Kusnezoffii 26 g

Radix Dipsaci 26 g Rhizoma Et Radix Notopterygiis 26 g

Semen Persicae 26 g Radix Clematidis 76 g

Sea maple rattan 26 g Bombyx Batryticatus 26 g

Flos Lonicerae 26 g Rhizoma Alpiniae Officinarum 26 g

26 g cattle sunset 26 of Radix Glycyrrhizae g

The Fructus Tribuli 26 g Cortexs Eucommiae 26 g

Herba Menthae 26 g Rhizoma Cimicifugaes 26 g

Radix Saposhnikoviae 26 g Radix Angelicae Sinensis 30.9g

Fructus Forsythiae 26 g Radix Angelicae Pubescentiss 26 g

Herba Taxilli 10 g spend 52 g

Rhizoma Gastrodiae 52 g Herba Lycopodii 104g

Herba speranskiae tuberculatae 104g processs Pyritum 78g

Moschus 3 g Borneolum Syntheticums 5 g

Cortex Cinnamomi 26g Flos Caryophylli 26g

Sanguis Draxonis 5 g Olibanum 5.1g

Myrrha 5 g

Amount to: 1,000g

The preparation method of this plaster is: at first with Moschus 3g, Borneolum Syntheticum 5g, Cortex Cinnamomi 26g, Flos Caryophylli 26g, Sanguis Draxonis 5g, Olibanum 5.1g, it is that 120 order smalls are deposited that seven kinds of Chinese medicines of Myrrha 5g are pulverized by its metering, other 26 kinds of Chinese medicines are dropped in the Oleum Sesami by weight soaked 36 hours, the ratio of Oleum Sesami and 26 kinds of medicines, it serves as an amount of soaking whole Chinese medicines with Oleum Sesami, all become sallow to the medicine color with slow fire with the medicine that soaks is fried, can not explode blackly, it is clean to pull filter then out, and the Oleum Sesami that is left is measured, carrying out compatibility in the ratio of every jin, a traditional unit of weight of oil and 250g Plumbum preparatium again concocts, one fixes on the slowly process of preparing Chinese medicine under the slow fire during process of preparing Chinese medicine, and the twist that does not stop, when Plumbum preparatium could be from fire after the Oleum Sesami strand is mixed evenly.Behind fire,, washed 96 hours, or soaked 120 hours, changed water once in per 8 hours with cold water with running water with the Plumbum preparatium and the Oleum Sesami cream that prepare, after again it being reheated fusing at last, seven kinds of powder of Chinese herbs pulverizing earlier are blended into, strand is even, spread out on cloth or oilpaper, be plaster, can come into operation.

The usage of oral capsule and consumption: day clothes three times, early, a.p take half an hour, the usefulness that is taken at bed time evening is sent down with eliminating cold for resuscitation water, obeys 9 at every turn.As obey the back stomach discomfort, can be with early, a.p change into after meal.

The usage of plaster: at first the plaster heating is melted, be affixed on sore place behind Ipsilateral groin and the buttocks, changed once in three days, a side patient pastes a side, the bilateral patient pastes bilateral, as find that the patient is red and swollen after forcing on, and get blister, it can be taken off, use the ginger slice wiping, paste after treating again, or do not paste daytime, paste night.

Period in a medicine is avoided tea, Semen phaseoli radiati, wine, hormone medicine.The careful clothes of anemia of pregnant woman.

Claims

1, pure Chinese medicinal preparation of treatment ischemic necrosis of femoral head disease and preparation method thereof, it is characterized in that: this Therapeutic Method has oral capsule and Dressed plaster to use simultaneously.The 24 kinds of Chinese medicinal ingredients and the proportion of oral capsule preparation are as follows:

Radix Angelicae Sinensis 12.8%-13.1% Olibanum 5.1%-5.15%

Flos Carthami 1.25%-1.3% Sanguis Draxonis 12.5%-13%

Herba Ephedrae 7.65%-7.7% Radix Dipsaci 7.6%-7.7%

Fructus Chaenomelis 1.25%-1.3% Semen Cucumidis sativi 7.6%-7.7%

Catechu 2.5%-2.6% Radix Angelicae Dahuricae (Radix Heraclei Scabridi) 2.5%-2.6%

Radix Saposhnikoviae 1.25%-1.3% Myrrha 3.8%-3.8%

The Radix Stephaniae Tetrandrae 2.5%-2.6% river 2.5%-2.6% of Qiang

Cattle sunset 3.8%-3.9% drynaria baronii 1.2%-1.3%

Radix Aconiti 1.25%-1.3% Radix Aconiti Kusnezoffii 1.2%-1.3%

The yellow 3.8%-3.9% eupolyphage sece steleophaga of Zhu 3.8%-3.9%

Radix Et Rhizoma Rhei 3.8%-3.9% Pyritum 3.8%-3.9%

Fructus Forsythiae 3.8%-3.9% Borneolum Syntheticum 1.2%-1.3% its preparation method is with the oven dry respectively in proportion of each component, mix the metering back respectively, and pulverizing is 120 orders, and being mixed then incapsulates, dress 0.45g in every capsule, it is standby after the capping of imitative pseudo-bottle to pack into by a fixing grain number.

Dressed plaster is prepared from by 33 kinds of Chinese medicines and Plumbum preparatium, Oleum Sesami, and its Main Ingredients and Appearance and proportion are as follows:

Radix Aconiti 2.5%-2.7% Radix Aconiti Kusnezoffii 2.5%-2.7%

Radix Dipsaci 2.5%-2.7% Rhizoma Et Radix Notopterygii 2.5%-2.7%

Semen Persicae 2.5%-2.7% Radix Clematidis 2.5%-2.7%

Sea maple rattan 2.5%-2.7% Bombyx Batryticatus 2.5%-2.7%

Flos Lonicerae 2.5%-2.7% Rhizoma Alpiniae Officinarum 2.5%-2.7%

Radix Glycyrrhizae 2.5%-2.7% cattle sunset 2.5%-2.7%

Fructus Tribuli 2.5%-2.7% Cortex Eucommiae 2.5%-2.7%

Thin He 2.5%-2.7% Rhizoma Cimicifugae 2.5%-2.7%

Radix Saposhnikoviae 2.5%-2.7% Radix Angelicae Sinensis 2.8 2%-2.8 5%

Fructus Forsythiae 2.5%-2.7% Radix Angelicae Pubescentis 2.5%-2.7%

Herba Taxilli 1%-1.1% Flos Carthami 5.2%-5.3%

Rhizoma Gastrodiae 5.2%-5.3% Herba Lycopodii 10.4%-5.45%

Herba speranskiae tuberculatae 10.4%-10.45% processs Pyritum 7.8%-7.8 5%

Moschus 0.3%-0.31% Borneolum Syntheticum 0.5%-0.53%

Cortex Cinnamomi 2.6%-2.62% Flos Caryophylli 2.6%-2.62%

Sanguis Draxonis 0.5%-0.53% Olibanum 0.51%-0.53%

Myrrha 0.5%-0.53% Plumbum preparatium is an amount of, and Oleum Sesami is an amount of.

Preparation method is: at first with Moschus, Borneolum Syntheticum, Cortex Cinnamomi, Flos Caryophylli, Sanguis Draxonis, Olibanum, it is that 120 orders are deposited that Myrrha is pulverized in proportion; Other 26 kinds of Chinese medicines are dropped in the Oleum Sesami in proportion soaked 36 hours, the ratio of Oleum Sesami and 26 kinds of Chinese medicines, serves as an amount of with Oleum Sesami to soak whole Chinese medicines, it is sallow with slow fire the medicine that soaks being exploded to the medicine complexion changed, can not explode blackly, it is clean to pull filter then out, and the Oleum Sesami that is left is measured, carrying out compatibility in the ratio of every jin, a traditional unit of weight of oil and 250g Plumbum preparatium again concocts, must be under slow fire during the process of preparing Chinese medicine slowly the process of preparing Chinese medicine, the twist that does not stop, when Plumbum preparatium is twisted in Oleum Sesami mix evenly after, could be from fire, behind fire with the Plumbum preparatium for preparing, Oleum Sesami cream cleaned 96 hours with running water, or soaked 120 hours with cold water, changed water once in per 8 hours, after again it being reheated fusing at last, seven kinds of Chinese medicines pulverizing earlier are blended into, strand is even, be spread out on cloth or the oilpaper, be plaster.