CN1294143C - 能在体内或体外改变卵泡生长的卵母细胞因子的核苷酸序列和氨基酸序列 - Google Patents
能在体内或体外改变卵泡生长的卵母细胞因子的核苷酸序列和氨基酸序列 Download PDFInfo
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
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Abstract
Description
处理组 | 平均排卵率(范围) |
抗-KLH(n=5只动物) | 1.6(1-2) |
抗-GDF-9B肽(5) | 0.2*(0-1) |
处理组 | GDF-9B | GDF-9 |
牛α乳清蛋白 | <0.060 | <0.060 |
GDF-9B | 2.177(±0.163) | 0.590(±0.058) |
处理组 | 卵巢体积(平均范围) | 1-2型卵泡数(平均范围) | 3-4型卵泡数(平均范围) | 囊状卵泡数(平均范围) |
KLH(3) | 486(353-651) | 15180(11623-17433) | 63(61-65) | 28(22-37) |
GDF-9B肽-KLH(5) | 296(149-488) | 8147(3221-13786) | 0 | 0 |
GDF-9肽-KLH(2) | 284(248-303) | 16278(10152-25745) | 0 | 4(0-11) |
处理组 | [3H]胸腺嘧啶掺入量(cpm) |
对照 | 3256±283 |
重组绵羊(o)-GDF-9B | 6291±503*** |
Claims (38)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
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NZ502796 | 2000-06-15 | ||
NZ502796A NZ502796A (en) | 2000-06-15 | 2000-06-15 | Nucleotide and amino acid sequences of oocyte factors related to GDF-9B or GDF-9 |
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CN1636012A CN1636012A (zh) | 2005-07-06 |
CN1294143C true CN1294143C (zh) | 2007-01-10 |
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CNB018112722A Expired - Fee Related CN1294143C (zh) | 2000-06-15 | 2001-06-15 | 能在体内或体外改变卵泡生长的卵母细胞因子的核苷酸序列和氨基酸序列 |
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US (2) | US7098183B2 (zh) |
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NZ (1) | NZ502796A (zh) |
RU (1) | RU2270862C2 (zh) |
WO (1) | WO2001096393A2 (zh) |
ZA (1) | ZA200210122B (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101525662B (zh) * | 2009-04-02 | 2011-08-17 | 西北农林科技大学 | 一种用gdf5基因预示和鉴定秦川牛体尺大小的分子标记方法 |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ519330A (en) * | 2002-05-30 | 2004-12-24 | George Henry Davis | New sequences for altering mammalian ovarian function and ovulation rate |
EP1522311A1 (fr) * | 2003-10-10 | 2005-04-13 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | Utilisation de la somatostine ou d'un de ses analogues pour préparer un médicament destiné à réguler la réserve folliculaire ovarienne chez la femme non ménopausée |
US20060234274A1 (en) * | 2005-03-29 | 2006-10-19 | Auckland Uniservices Limited | Methods of diagnosis |
CN101272804A (zh) * | 2005-07-18 | 2008-09-24 | 阿德莱德研究及创新控股有限公司 | 调节颗粒细胞的凋亡 |
CN108977553B (zh) * | 2018-09-05 | 2021-08-31 | 湖北省农业科学院畜牧兽医研究所 | 蛋鸭环状RNA circ_13267及其检测试剂、方法与应用 |
CN108977554B (zh) * | 2018-09-05 | 2021-08-31 | 湖北省农业科学院畜牧兽医研究所 | 蛋鸭环状RNA circ_13034及其检测试剂、方法与应用 |
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WO1996036710A1 (en) * | 1995-05-18 | 1996-11-21 | Genetics Institute, Inc. | Bmp-15 compositions |
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US5821056A (en) * | 1993-01-12 | 1998-10-13 | The Johns Hopkins University School Of Medicine | Growth differentiation factor-9 |
ES2214743T3 (es) * | 1997-09-19 | 2004-09-16 | Biopharm Gesellschaft Zur Biotechnologischen Entwicklung Von Pharmaka Mbh | Combinacion de citocinas con actividad neurotrofica. |
US6872698B2 (en) * | 1998-07-06 | 2005-03-29 | Scion Pharmaceuticals, Inc. | Methods for treating neurological injuries and disorders |
EP1135154B1 (en) * | 1998-12-01 | 2003-05-07 | Akzo Nobel N.V. | Improvement of folliculogenesis |
NZ500844A (en) * | 2000-05-05 | 2003-06-30 | Agres Ltd | Nucleotide sequences (mutated GDF-9B polypeptides) involved in increasing and decreasing mammalian ovulation rate |
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WO1996036710A1 (en) * | 1995-05-18 | 1996-11-21 | Genetics Institute, Inc. | Bmp-15 compositions |
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CN101525662B (zh) * | 2009-04-02 | 2011-08-17 | 西北农林科技大学 | 一种用gdf5基因预示和鉴定秦川牛体尺大小的分子标记方法 |
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AU784276B2 (en) | 2006-03-02 |
MXPA02012378A (es) | 2004-09-10 |
NZ502796A (en) | 2003-02-28 |
RU2270862C2 (ru) | 2006-02-27 |
RU2003100883A (ru) | 2005-01-20 |
BR0111685A (pt) | 2007-05-29 |
EP1294755A2 (en) | 2003-03-26 |
ZA200210122B (en) | 2003-09-30 |
AU6795001A (en) | 2001-12-24 |
CA2410532A1 (en) | 2001-12-20 |
WO2001096393A2 (en) | 2001-12-20 |
WO2001096393A3 (en) | 2002-08-08 |
WO2001096393A9 (en) | 2002-11-28 |
CN1636012A (zh) | 2005-07-06 |
US20040267003A1 (en) | 2004-12-30 |
AU784276C (en) | 2007-11-15 |
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