CN1291723C - 作为肿瘤相关抗原的伸展1型链鞘糖脂 - Google Patents

作为肿瘤相关抗原的伸展1型链鞘糖脂 Download PDF

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Publication number
CN1291723C
CN1291723C CNB008197881A CN00819788A CN1291723C CN 1291723 C CN1291723 C CN 1291723C CN B008197881 A CNB008197881 A CN B008197881A CN 00819788 A CN00819788 A CN 00819788A CN 1291723 C CN1291723 C CN 1291723C
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China
Prior art keywords
cells
tumor
mab
stands
fucose
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Expired - Lifetime
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CNB008197881A
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English (en)
Chinese (zh)
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CN1460022A (zh
Inventor
S·莱弗里
S－I·哈克莫利
M·斯特劳德
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Biomembrane Institute
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Biomembrane Institute
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/006—Heteroglycans, i.e. polysaccharides having more than one sugar residue in the main chain in either alternating or less regular sequence; Gellans; Succinoglycans; Arabinogalactans; Tragacanth or gum tragacanth or traganth from Astragalus; Gum Karaya from Sterculia urens; Gum Ghatti from Anogeissus latifolia; Derivatives thereof
    • C08B37/0063—Glycosaminoglycans or mucopolysaccharides, e.g. keratan sulfate; Derivatives thereof, e.g. fucoidan

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
CNB008197881A 2000-07-03 2000-07-03 作为肿瘤相关抗原的伸展1型链鞘糖脂 Expired - Lifetime CN1291723C (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2000/018219 WO2002002127A1 (en) 2000-07-03 2000-07-03 Extended type 1 chain glycosphingolipids as tumor-associated antigens

Publications (2)

Publication Number Publication Date
CN1460022A CN1460022A (zh) 2003-12-03
CN1291723C true CN1291723C (zh) 2006-12-27

Family

ID=21741553

Family Applications (1)

Application Number Title Priority Date Filing Date
CNB008197881A Expired - Lifetime CN1291723C (zh) 2000-07-03 2000-07-03 作为肿瘤相关抗原的伸展1型链鞘糖脂

Country Status (6)

Country Link
EP (1) EP1307207A4 (enExample)
JP (1) JP2004502025A (enExample)
KR (1) KR100666238B1 (enExample)
CN (1) CN1291723C (enExample)
AU (2) AU2000260652B2 (enExample)
WO (1) WO2002002127A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5331293B2 (ja) * 2006-04-28 2013-10-30 公益財団法人野口研究所 多様性を表現するオリゴ糖またはその誘導体
KR101432474B1 (ko) * 2008-09-07 2014-08-21 글라이코넥스 인코포레이티드 항-연장된 ⅰ형 글라이코스핑고지질 항체, 이의 유도체 및 용도
CN104655859B (zh) * 2013-11-21 2017-10-03 苏州中赢医疗科技有限公司 乳腺癌的诊断标志物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6083929A (en) * 1991-05-06 2000-07-04 The Biomembrane Institute Extended type 1 chain glycosphingolipids as tumor-associated antigens
WO1992019634A1 (en) * 1991-05-06 1992-11-12 The Biomembrane Institute Extended type 1 chain glycosphingolipids as tumor-associated antigens

Also Published As

Publication number Publication date
JP2004502025A (ja) 2004-01-22
AU2000260652B2 (en) 2005-10-27
EP1307207A1 (en) 2003-05-07
CN1460022A (zh) 2003-12-03
KR20030068120A (ko) 2003-08-19
WO2002002127A1 (en) 2002-01-10
EP1307207A4 (en) 2005-12-14
AU6065200A (en) 2002-01-14
KR100666238B1 (ko) 2007-01-09

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C06 Publication
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SE01 Entry into force of request for substantive examination
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CX01 Expiry of patent term

Granted publication date: 20061227