CN1288725A - Preparation of serial veterinary injecta products - Google Patents
Preparation of serial veterinary injecta products Download PDFInfo
- Publication number
- CN1288725A CN1288725A CN 00119159 CN00119159A CN1288725A CN 1288725 A CN1288725 A CN 1288725A CN 00119159 CN00119159 CN 00119159 CN 00119159 A CN00119159 A CN 00119159A CN 1288725 A CN1288725 A CN 1288725A
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- CN
- China
- Prior art keywords
- injection
- water
- eota
- preparation
- enrofloxacin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
The persent invention discloses a preparation method of injection for fowl and livestock. It is made up by using ennoxacin, socium hydroxide solution, EOTA-2Na and injection water through a certain preparation process. Said invented injection is unique in mechanism, obvious in effect, extensive in application, high in efficiency and low in toxicity.
Description
The present invention relates to a kind of poultry and use medicine.
All kinds of veterinary drugs of Xiao Shouing are used for the control of poultry in the market, and its protection effect is not good enough, and the curative effect of curing the disease is general, also do not have discovery to have sterilization, disease-resistant special effect medicine to come out.
The objective of the invention is at above-mentioned defective, provide a kind of effect remarkable, of many uses, efficient, low toxicity and good absorbing, instant effect, curative effect time are long, and what have no side effect herds enlightening 988,2000 serial diseases prevention medicines.
The solution of the present invention is formulated by enrofloxacin, sodium hydroxide solution, EOTA-2Na and water for injection processing.
One, prescription: enrofloxacin 25g
40% sodium hydroxide solution 10-40ml
EOTA-2Na0.5-1.5g
Water for injection 1000ml
Two, manufacturing process:
Wash bottle: at first the 12-15ml cillin bottle is slightly washed, fine purifiation, 100 ℃ of oven dry 30 minutes are cooled off stand-by.
1, enrofloxacin 25g being added an amount of water for injection makes it abundant dilution, stirs.
2, add 40% sodium hydroxide solution 10-40ml, make it dissolving.
3, filling water for injection is reconciled PH to 9.5-10.5 to full dose 1000ml.
4, add EOTA-2Na0.5-1.5g again, stir.
5, with 120 ℃ of autoclave cabinet sterilizations, 30 minutes, intermediate is filling-in and closing bottle by applying cap after the assay was approved.
6, lamp inspection, chemical examination, labeling, the packing warehouse-in.
The present invention draws optimum formula through surplus 880 development test successes, has wide spectrum, efficient, low toxicity, has no side effect, and is sterilization, antiviral, moves back the special effect medicine of hyperpyrexia.
Mechanism of action uniqueness of the present invention, effect is remarkable, and is of many uses.Cure mainly: escherichia coli, pneumonia, bronchitis, typhoid fever, paratyphoid fever, pig erysipelas, viral influenza, fowl cholera, septicemia, cattle and sheep Bu Shi bar pathogenic bacteria, diseases of urinary system, skin infections etc. such as poultry acute and chronic respiratory tract disease, a mouthful hoof fester, yellow scours, Hakuri, viral diarrhea, due to illness poison, bacterial all kinds of high febrile illnesses.And atypical swine fever, fowl plague also there is certain control effect.
The scope of application of the present invention is wide, is not subjected to the area and the restriction of weather conditions, and route of administration makes things convenient for, but both direct injection, again can be oral or add water and take.
Three, subject range:
(1) fowl diseases:
1, gallisepticum chicken disease (comprising chronic respiratory tract disease and synovitis)
2, avian colibacillosis (comprising pericarditis, perihepatitis, peritonitis, ophthalmia etc.)
3, white diarrhea disease (comprising the Arizona salmonellosis)
4, fowl cholera (comprising pest of duck, pasteurellosis bacillus etc.)
5, secondary haemophilus disease (infective rhinitis)
6, staphylococcus aureus disease (septicemia)
7, the hyperpyrexia that causes such as viral influenza.
In aviculture, the common mixed infection of above-mentioned eqpidemic disease.As the sick concurrent colibacillosis of mycoplasma gallinarum, the sick concurrent secondary haemophilus disease of mycoplasma gallinarum, some chicken group even three or four kinds of diseases are concurrent popular.
Recommend usage and dosage:
1, drink-service: add 0.5 kilogram of company of water with this product 1ml and drank 1-3 days.
2, intramuscular injection: chicken per kilogram of body weight this product 0.1ml, most condition of disease are once cured.Cured person was not injected once in second day more as yet.
3, prophylactic treatment is made in the combined vaccine inoculation, at mycoplasma gallinarum and Pullorum Disease severe contamination chicken house, for killing the pathogenic bacteria property deactivation substance that each hatching egg brings, during chicken one age in days injection horse Garrick vaccine (virus attenuated Seedling or bacillary inactivated bacteria are suitable for this method), this product 1ml mixed in the good vaccine of dilution inject, use for 100 chickling.Can significantly reduce the Hakuri sickness rate of mycoplasma in the chicken.The immune effect of horse Garrick vaccine can not reduce yet.
(2) swine diseases:
1, piglet pujos blancos, yellow scours, red diarrhea, bowel oedema disease colibacillosis
2, Mycoplasma bronchopneumonia, asthma
3, baby swine paratyphoid
4, pasteurella multocida disease
5, the popular pneumonia of endemicity, pleura pneumonia
6, pig erysipelas
7, brucellosis
8, atrophic rhinitis
9, streptococcicosis
10, epidemic diarrhea
11, mastitis---metritis---agalactia syndrome
Recommend usage and consumption:
Use this product intramuscular injection, once measure every 10kg body weight 1ml.Piglet pujos blancos and baby swine paratyphoid are generally once cured.All the other are secondary every day, by every 10kg body weight 1.5ml intramuscular injection, once a day.
(3) cattle and sheep disease
1, enterobacteria property diarrhoea
2, e. coli septicemia
3, pleuropneumonia (Mycoplasma pneumonia)
4, brucellosis
5, pasteurella multocida disease
6, cattle anthrax
7, Listeria monocytogenes (comprise the nervous symptoms occurs person)
8, breast class---metritis
9, the innominate high fever that causes by antibacterial, virus
Recommend usage and dosage:
Use this product intramuscular injection, once measure every 10kg body weight 1ml, every day, secondary was pressed 7.5kg body weight 1ml, once a day (horse class disease is treated with reference to this method).
(4) dog disease
Digestive tract, respiratory tract, urinary system, reproductive system organ infection, skin infection, wound is suppurated, the gastroenteritis haemorrhagica that external otitis, colibacillosis cause etc.
Recommend usage and dosage:
Use this product intramuscular injection, once measure every 10kg body weight 1ml, every day secondary.
(5) rabbit:
1, staphylodermatitis, endocarditis
2, pseudomonas aeruginosa meningitis
3, pneumonia
4, osteomyelitis
5, the multiclass diarrhoea that causes of escherichia coli, dysentery etc.
Recommend usage and consumption:
Use this product intramuscular injection, every 1kg body weight 0.1ml intramuscular injection, every day secondary or every 1kg body weight 0.2ml, once a day.
Claims (1)
1, a kind of preparation method of veterinary injecta is formulated by enrofloxacin, sodium hydroxide solution, EOTA-2Na and water for injection processing,
One, prescription:
Enrofloxacin 25g
40% sodium hydroxide holds liquid 10-40ml
EOTA-2Na 0.5-1.5g
Water for injection 1000ml
Two, production process:
1., enrofloxacin 25g is added an amount of water for injection make it abundant dilution, stir,
2., add 40% sodium hydroxide solution 10-40ml, make it dissolving,
3., filling water for injection is to full dose 1000ml, reconciles PH to 9.5-10.5,
4., again add EOTA-2Na0.5-1.5g, stir,
5., with 120 ℃ of autoclave cabinet sterilizations, 30 minutes, intermediate is filling-in and closing bottle by applying cap after the assay was approved,
6., lamp inspection, chemical examination, labeling, the packing warehouse-in.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00119159 CN1288725A (en) | 2000-06-30 | 2000-06-30 | Preparation of serial veterinary injecta products |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 00119159 CN1288725A (en) | 2000-06-30 | 2000-06-30 | Preparation of serial veterinary injecta products |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1288725A true CN1288725A (en) | 2001-03-28 |
Family
ID=4587531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 00119159 Pending CN1288725A (en) | 2000-06-30 | 2000-06-30 | Preparation of serial veterinary injecta products |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1288725A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101810569A (en) * | 2010-05-22 | 2010-08-25 | 鼎正动物药业（天津）有限公司 | Enrofloxacin injection liquid and preparation method thereof |
| CN101961335A (en) * | 2010-06-30 | 2011-02-02 | 洛阳惠中兽药有限公司 | Enrofloxacin hexahydrate-containing composition and application thereof in preparing medicament for treating or preventing poultry diseases |
| CN1965834B (en) * | 2005-11-18 | 2012-01-25 | 天津瑞普生物技术股份有限公司 | Enrofolxacn solution containing clustered water used for animal |
-
2000
- 2000-06-30 CN CN 00119159 patent/CN1288725A/en active Pending
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1965834B (en) * | 2005-11-18 | 2012-01-25 | 天津瑞普生物技术股份有限公司 | Enrofolxacn solution containing clustered water used for animal |
| CN101810569A (en) * | 2010-05-22 | 2010-08-25 | 鼎正动物药业（天津）有限公司 | Enrofloxacin injection liquid and preparation method thereof |
| CN101961335A (en) * | 2010-06-30 | 2011-02-02 | 洛阳惠中兽药有限公司 | Enrofloxacin hexahydrate-containing composition and application thereof in preparing medicament for treating or preventing poultry diseases |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| AD01 | Patent right deemed abandoned | ||
| C20 | Patent right or utility model deemed to be abandoned or is abandoned |