CN1278596C - Lithium enriched Chineses wolfberry fruit and its producing method - Google Patents
Lithium enriched Chineses wolfberry fruit and its producing method Download PDFInfo
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- CN1278596C CN1278596C CN 200410063062 CN200410063062A CN1278596C CN 1278596 C CN1278596 C CN 1278596C CN 200410063062 CN200410063062 CN 200410063062 CN 200410063062 A CN200410063062 A CN 200410063062A CN 1278596 C CN1278596 C CN 1278596C
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Abstract
The present invention discloses a Lithium-enriched matrimony vine and a producing method thereof. In the present invention, lithium carbonate or lithium chloride solution is sprayed on leaf surfaces of the matrimony vine from the squaring stage to the early bloom stage, and then matrimony vine products containing 8.518 ug/g to 27.200 ug/g of lithium can be obtained through a plant transform function. Thus, people can supply the microelement lithium through daily meals so as to enhance the body immunity and reach the effect on preventing and curing diseases. The method of the present invention is stable, reliable, simple in operation, easy in popularity and high in social benefit and economic benefit.
Description
Technical field
The invention belongs to fruit growing method field, particularly a kind of lithium enriched Chineses wolfberry fruit and production method thereof.
Background technology
Lithium is the nonessential trace element of human body, but but is the trace element (" trace element and human nutrition health " that the World Health Organization published in 1996) that the human life activity has essential function.Lithium is a kind of alkaline element with high activity, is distributed in the body fluid of body, and it can reach balance rapidly in liver, kidney, then needs the complete equilibrium establishment of 1 week ability in muscle and bone.After, Cade in 1949 effective since nineteen twenty-four Weiss reported first lithium salts treatment diabetes is used for the treatment of lithium salts the mental disease achieving success, lithium salts is widely used in clinical as a kind of antipsychotics, after this, along with deepening continuously of research work, people have had more understanding to the effect and the clinical practice of lithium, and the application of lithium is also extensive day by day.
Integrate, the effect of lithium is mainly reflected in following aspect:
1. lithium has regulating action to immune system: lithium can strengthen T emiocytosis IL-2, and monocyte secreting tumor necrosis factor (TNF
a) and the expression of corresponding mRNA, these three kinds of factors are regulatory factors important in the body immune system, it also is the important anti-knurl factor, but the toxic and side effect of the IL-2 of external source is very big, the trend various kinds of cell factor on probation at present, or IL-2 lowering its toxicity, but provides the cell factor of a large amount of reorganization still to have any problem in conjunction with the other therapies complex treatment at present, therefore, it is necessary with the consumption and the toxic and side effect that reduce IL-2 to seek a kind of effective I L-2 reinforcing agent.Lithium is a kind of micromolecular immuno modulating agent, simple in structure, be used for some disease of clinical treatment, if and some other antitumor drug thing or biological respinse modulation agent merging application, be expected to improve curative effect, therefore, lithium salts all has great potentiality in basic research with in clinical practice, can bring into play the effect of its uniqueness undoubtedly.
2. lithium can be regulated central nervous system: with the continuous increase of operating pressure, suffer from mania with the quickening pace of modern life, the people of phrenoblabias such as depression and emotion symptom is more and more, and lithium is used for effectively treating this class phrenoblabia in worldwide.In the 4th the spiritual Neuscience meeting of not long ago holding of China, a WHO is that announce, that 15 centers of 14 countries in global five continents are carried out, comprise that name is to the prescription on individual diagnosis person's of general hospital latest survey demonstration surplus in the of 25000, depression has become one of modal disease of global general hospital, but usually ignored by the clinician or fail to pinpoint a disease in diagnosis, mistaken diagnosis.50% patient is simultaneously with other somatization, for example, and sleep-disorder, headache, gastrointestinal discomfort, tired, body weight reduces, because depression is a mental handicape of outbreak repeatedly, many patients seek medical advice for one time one everywhere, are accepting too much body inspection simultaneously, these patients' economic pressures are huge, simultaneously, for all very limited China of medical treatment input and medical resource, more be unable to undergo such waste.Depression identification in time and treatment not only are to improve patient physiological, and mental functioning be the more important thing is the raising patients ' life quality.The Ministry of Public Health with depression as one of the spirit/psychological illness of main control in China " 2002---2010 mental hygiene development plans ".Lithium influences the inside and outside electrolyte concentration of cell, extracellular lithium can active cell in ATP enzyme and control pump, make that na concn reduces in the cell, and then have influence on release and the picked-up and the cell excitement of monoamine neurotransmitter, and produce the anti-manic effect that removes.
3. lithium can be treated alzheimer's disease: the patient who suffers from alzheimer's disease, the excessive phosphorylation of microtubule bindin, lithium can suppress glycogen and contain kinase enzyme-3 (GSK-3), because GSK-3 regulates tan, lithium reduces the tan phosphorylation by the direct and reversible inhibition to GSK-3, increases tan and is incorporated into microtubule.The result shows that how lithium plays a role provides neodoxy in central nervous system, and proposes to use the possibility that lithium is prevented and treated the excessive phosphorylation of alzheimer's disease tan albumen, in order to the new interference method of exploitation alzheimer's disease.
4. lithium and cardiovascular system: epidemiology survey is found, be negative correlation between the U.S.'s nearly 100 cities drinking-water lithium concentration and the atherosclerotic deaths from heart disease rate, zoopery also shows, lithium can cause the change of not strain of the heart phase of rat, coronary blood flow is increased, decreased heart rate, convergent force strengthens, it is low also to send out Keshan disease area drinking water and patients serum's lithium content existing, obtains certain effect with lithium carbonate treatment Keshan disease.
5. lithium and hemopoietic system: lithium has spread effect to myeloid element, patient's peripheral blood granulocyte and the total white blood cells of accepting the lithium salts treatment increase, leucocyte and macrophage activity strengthen, immunologic function improves, after the aplastic anemia patient takes lithium salts, blood platelet and red blood cell increase, and the green blood spread effect of lithium is relevant with promotion granular leukocyte colony stimulating activity with lithium stimulation neutrophil leucocyte hyperplasia.
6. lithium is to biomembranous protective effect: the radius of lithium is little; and polarizability is big; with the lithium be the center complex its bigger strength and toughness is arranged; add material as biology; lithium can infiltrate in the various membrane structures, to increase the stability of membrane structure, report is arranged once; with the antipsychotic while of lithium salts, cured the canker that does not heal for a long time.
7. lithium and endocrine system: lithium has more significantly effect to thyroid gland, parathyroid gland and adrenal cortex, and lithium salts can suppress thyroid function, and lithium treatment thyroid gland is hyperfunction clinically, thyrotoxicosis and thyroid cancer.Lithium has the para-insulin effect.Lithium all has ILA to liver, adipocyte and skeletal muscle, diaphram, show that these cellular uptake glucose increase, blood sugar concentration reduces, lactic acid generates and reduces, glycogen is synthetic to be increased, glycogen heteroplasia and cholesterol and fatty acid press down synthetic being subjected to of liver, and these effects are rather similar with insulin action, and the effect of lithium-activated glycogen synthetase is stronger than insulin; Lithium under certain condition (when lactic acid and pyruvic acid exist) can activate glycogen phosphorylase, and insulin is suppressed; Insulin can suppress the activation of adrenaline to the phosphorylase activity, can also activate pyruvate dehydrogenase simultaneously, and lithium does not but have effect to these enzymes, and this just points out lithium and insulin that synergy is arranged in vivo, in a word, and important cation (Na in lithium and the body
+, K
+, Ca
2+, Mg
2+) the same, be keep the relevant enzyme of those carbohydrate intermediate supersessions active needed.
At present, from reporting in a large number, adopt lithium chloride (LiCl) clinically mostly, lithium carbonate (Li both at home and abroad
2CO
3), lithium hydroxide inorganic matter tablets such as (LiOH) is treated above-mentioned illness, but above-mentioned lithiumation thing conventional tablet toxicity is big, side effect is more, particularly when taking medicine that blood concentration peaked period in back two hours, the digestive tract irritation often occurs, be difficult to make the patient to accept, more be unfavorable for the long term maintenance treatment.Therefore, provide a kind of and can effectively prevent and treat above-mentioned illness, the rich lithium product that has no side effect again is very important.
Summary of the invention
The object of the present invention is to provide a kind of have no side effect rich lithium product---lithium enriched Chineses wolfberry fruit;
Another object of the present invention is to provide the production method of above-mentioned lithium enriched Chineses wolfberry fruit.
A kind of lithium enriched Chineses wolfberry fruit is characterized in that lithium content is 8.518ug/g dry weight～27.200ug/g dry weight in the matrimony vine;
A kind of production method of lithium enriched Chineses wolfberry fruit is characterized in that squaring period matrimony vine to coming into bloom, carrying out foliage-spray one to twice with lithium carbonate or lithium chloride solution, and fruit picking gets final product after 20-30 days;
The concentration of above-mentioned lithium carbonate or lithium chloride is 3-6 mg/litre (3000-6000ppm), is preferably 5-6 mg/litre (5000-6000ppm).
The present invention is a carrier with the natural plants body with enriching lithium, by spray lithium carbonate or lithium chloride solution squaring period to flowering stage plant, plant is transformed by self to be enriched in lithium in the plant corpus, come the microelement-supplementing lithium by daily meals then, thereby the enhancing body immunity reaches the effect of preventing and curing diseases.
The present invention selects for use be the enriching lithium of generally acknowledging in the world plant---lycium barbarum (Lyciumbarbarum..L.) carries out rich lithium, according to surveying and determination, lithium content is 1～2ppm in the lycium barbarum fruit; Lithium content is 104～176ppm in the blade; Carpopodium is 21ppm.I distinguish, and lithium content is 38～58ppm in the soil because the type of kind and plant growing is different, in the plant lithium content variation very big, between 0.4ug/g～1000ug/g, so the ability of lycium barbarum enriching lithium is also very big.
It is that carrier carries out rich lithium that the present invention promptly adopts matrimony vine, the matrimony vine of adopting the present invention to obtain, and its lithium content can reach 8.518ug/g dry weight～27.200ug/g dry weight, is 8-16 times of common matrimony vine (mensuration content is 1.707ug/g).
Method of the present invention is reliable and stable, and is simple and easy to do, easily popularizes, and very high social benefit and economic benefit are arranged.
Embodiment
Embodiment 1:
With lycium barbarum (No. one, peaceful Qi) is carrier, squaring period of matrimony vine to coming into bloom, carry out foliage-spray once with the lithium carbonate solution of 5mg/l (5000ppm), till the dropping liquid of blade face, used spraying machine fogging degree is good, must not use with other agricultural chemicals, chemical fertilizer.Fruit picking after 20-30 days, after testing, lithium content is the 27.200ug/g dry weight in the matrimony vine.
Embodiment 2:
With lycium barbarum (No. one, peaceful Qi) is carrier, squaring period of matrimony vine to coming into bloom, carry out foliage-spray once with the lithium chloride solution of 5.5mg/l (5500ppm), till the dropping liquid of blade face, used spraying machine fogging degree is good, must not use with other agricultural chemicals, chemical fertilizer.Fruit picking after 20-30 days, after testing, lithium content is the 22.5ug/g dry weight in the matrimony vine.
Embodiment 3:
With lycium barbarum (No. one, peaceful Qi) is carrier, squaring period of matrimony vine to coming into bloom, carry out foliage-spray twice with the lithium chloride solution of 6.Omg/l (6000ppm), till the dropping liquid of blade face, used spraying machine fogging degree is good, must not use with other agricultural chemicals, chemical fertilizer.Fruit picking after 20-30 days, after testing, lithium content is the 21.468ug/g dry weight in the matrimony vine.
Embodiment 4:
With lycium barbarum (No. one, peaceful Qi) is carrier, squaring period of matrimony vine to coming into bloom, carry out foliage-spray twice with the lithium carbonate solution of 6mg/l (5500ppm), till the dropping liquid of blade face, used spraying machine fogging degree is good, must not use with other agricultural chemicals, chemical fertilizer.Fruit picking after 20-30 days, after testing, lithium content is the 23.45ug/g dry weight in the matrimony vine.
Embodiment 5:
With lycium barbarum (No. one, peaceful Qi) is carrier, squaring period of matrimony vine to coming into bloom, carry out foliage-spray once with the lithium carbonate solution of 3mg/l (3000ppm), till the dropping liquid of blade face, used spraying machine fogging degree is good, must not use with other agricultural chemicals, chemical fertilizer.Fruit picking after 20-30 days, after testing, lithium content is the 18.822ug/g dry weight in the matrimony vine.
Embodiment 6:
With lycium barbarum (No. one, peaceful Qi) is carrier, squaring period of matrimony vine to coming into bloom, carry out foliage-spray once with the lithium chloride solution of 4mg/l (4000ppm), till the dropping liquid of blade face, used spraying machine fogging degree is good, must not use with other agricultural chemicals, chemical fertilizer.Fruit picking after 20-30 days, after testing, lithium content is the 11.195ug/g dry weight in the matrimony vine.
Claims (4)
1. a lithium enriched Chineses wolfberry fruit is characterized in that lithium content is 8.518ug/g dry weight～27.200ug/g dry weight in the matrimony vine.
2. the production method of a lithium enriched Chineses wolfberry fruit is characterized in that squaring period matrimony vine to coming into bloom, carrying out foliage-spray one to twice with lithium carbonate or lithium chloride solution, and fruit picking gets final product after 20-30 days.
3. according to the production method of the described lithium enriched Chineses wolfberry fruit of claim 2, it is characterized in that: the concentration of above-mentioned lithium carbonate or lithium chloride is the 3-6 mg/litre.
4. according to the production method of claim 2 or 3 described lithium enriched Chineses wolfberry fruits, it is characterized in that: the concentration of above-mentioned lithium carbonate or lithium chloride is the 5-6 mg/litre.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410063062 CN1278596C (en) | 2004-07-13 | 2004-07-13 | Lithium enriched Chineses wolfberry fruit and its producing method |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410063062 CN1278596C (en) | 2004-07-13 | 2004-07-13 | Lithium enriched Chineses wolfberry fruit and its producing method |
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| Publication Number | Publication Date |
|---|---|
| CN1586109A CN1586109A (en) | 2005-03-02 |
| CN1278596C true CN1278596C (en) | 2006-10-11 |
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|---|---|---|---|
| CN 200410063062 Expired - Fee Related CN1278596C (en) | 2004-07-13 | 2004-07-13 | Lithium enriched Chineses wolfberry fruit and its producing method |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI634907B (en) * | 2011-12-27 | 2018-09-11 | 傑拓保護有限公司 | Peritoneal dialysis fluid |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102057848A (en) * | 2010-10-14 | 2011-05-18 | 宁夏农林科学院 | Cultivation method for realizing high yield of male sterile Chinese wolfberry and application |
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2004
- 2004-07-13 CN CN 200410063062 patent/CN1278596C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI634907B (en) * | 2011-12-27 | 2018-09-11 | 傑拓保護有限公司 | Peritoneal dialysis fluid |
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| Publication number | Publication date |
|---|---|
| CN1586109A (en) | 2005-03-02 |
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