CN1272370A - Eye ointment for curing myopia and its production process - Google Patents

Abstract

An eye ointment for curing myopia is made up by using 16 Chinese medicinal materials of ligusticum root, notoginseng, abalone shell, carthamus flower, dendrobium stem, hocquartia stem, phellodendron bark, chrysanthemum flower and peppermint, etc. as raw materials through the process of pulverizing, decocting, concentrating, then mixing with borneol, benzoin and medical vaseline and stirring them uniformly to obtain the finished product. Said eye ointment possesses the functions of clearing and activating the channels and collaterals, causing resuscitation and improving acuity of vision, regulating diopter, improving microcirculation and promoting metabolism of eye interior, can be applied on the acupoints of eye so as to attain the goal of curing myopia, and its visual improvement rates are 81.82%, 83.53% and 70.73% respectively.

Description

A kind of eye ointment and production technology thereof that is used for the treatment of myopia

The present invention relates to a kind of to all kinds of myopia and have and adjust and the eye ointment of correcting, particularly a kind of eye ointment that is used for the treatment of myopia, its commodity are called many prosperous medicine for treating myopia eye ointment, it is applicable to all kinds of near-sighted ophthalmics.

Myopia is a kind of common disease in the middle of China's teenager, and according to incompletely statistics, the people who suffers from myopia in the student accounts for 50-60%, directly affects their living and studying.Though wear glasses, can temporarily solve visual disorder, can not treat or eradicate myopia.Along with the prolongation of time, the increase at age and the excess eye-using in the learning life, the near-sighted number of degrees can be more and more higher, also will change glasses for the myopia again and not only increase expenditure and bother, also can be more and more heavier to the infringement of eye.

The objective of the invention is to treat myopia and a kind of eye ointment that is used for the treatment of myopia of development with smelting in order to prevent, it is that the multi-flavor rare Chinese medicine is carried out the strictness screening, and to drug dose, compound method, boil the duration and degree of heating and time, through repeatedly compatibility and prescription,, draw the preparation method of this product through actual verification.This product energy dredge the meridian passage, having one's ideas straightened out makes eye bright, and regulates diopter, and microcirculation improvement impels the mediation of eye discharge conduit, improves optic nerve, trifacial excitement levels.The eye ointment of development is smeared by the acupuncture point, and the therapy of drug osmotic is to reach the purpose of inner disease outer treat.

The present invention is achieved in that a kind of eye ointment that is used to be used for the treatment of myopia, and wherein, it is made by following raw materials by weight percent, Rhizoma Chuanxiong 15, Radix Notoginseng 20, Concha Haliotidis 15, Flos Carthami 10, Herba Dendrobii 20, Caulis Aristolochiae Manshuriensis 20, Cortex Phellodendri 15, Flos Chrysanthemi 20, Herba Menthae 20, Pollen Typhae 12, Radix Glycyrrhizae 12,30 parts of Radix Angelicae Sinensis, Fructus Aurantii 15, Semen Plantaginis 15, Poria 20, Radix Codonopsis 15, Borneolum Syntheticum 15, Benzoinum 15, medical ventolin 300.

The production technology of the present invention's eye ointment as previously discussed comprises the following steps:

The first step, with Rhizoma Chuanxiong 15, Radix Notoginseng 20, Concha Haliotidis 15, Flos Carthami 10, Herba Dendrobii 20, Caulis Aristolochiae Manshuriensis 20, Cortex Phellodendri 15, Flos Chrysanthemi 20, Herba Menthae 20, Pollen Typhae 12, Radix Glycyrrhizae 12, Radix Angelicae Sinensis 30, Fructus Aurantii 15, Semen Plantaginis 15, Poria 20, Radix Codonopsis 15 is removed impurity respectively, oven dry is pulverized standby then;

Second step, the Concha Haliotidis 15 after will pulverizing, Herba Dendrobii 20, Caulis Aristolochiae Manshuriensis 20, Cortex Phellodendri 15 is placed in the distilled water of 1500ml, with slow fire boiling 40 minutes, again with Rhizoma Chuanxiong 15, Radix Notoginseng 20, Herba Menthae 20, Flos Carthami 10, decocted again 30 minutes with slow fire in the Flos Chrysanthemi 20 adding decoction liquor, at last with Pollen Typhae 12, Radix Glycyrrhizae 12, Radix Angelicae Sinensis 30, Fructus Aurantii 15, Semen Plantaginis 15, Poria 20, Radix Codonopsis 15 add in the decoction liquor with slow fire and continue to decoct 20 minutes after-filtration, remove slag and be concentrated into 200 grams, are made as the A material;

The 3rd step, when the temperature of A material is reduced to 50-60 ℃, with Borneolum Syntheticum 15, Benzoinum 15, medical ventolin 300 join in the A material and stir.

The present invention to the treatment principle of myopia is: cold in nature, the sweet in the mouth of Semen Plantaginis, and the row liver is dredged kidney; Radix Codonopsis is flat, sweet in the mouth, invigorating the spleen and replenishing QI; Flat, the sweet in the mouth of Radix Glycyrrhizae property, spleen invigorating and in, separate hundred poison; Poria is flat, lightly seasoned, the spleen invigorating invigorating middle warmer; Warm in nature, the sweet-bitter flavor of Radix Notoginseng; Removing stasis to stop bleeding; Warm in nature, the bitter in the mouth of Flos Carthami, blood circulation promoting and blood stasis dispelling; Warm in nature, the acrid-sweet flavor of Rhizoma Chuanxiong can nourish blood, invigorates blood circulation, circulation of qi promoting, pain relieving; Warm in nature, the acrid-sweet flavor of Radix Angelicae Sinensis nourishes blood and blood; Cold in nature, the bitter in the mouth of Cortex Phellodendri rushes down the fire of the kidney fire and the part of the body cavity below the umbilicus, housing the bladder, kidneys and bowels; Cold in nature, the bitter in the mouth of Flos Chrysanthemi, makes eye bright at heat-clearing and toxic substances removing; Cool in nature, the bitter in the mouth of Herba Menthae, dispelling wind and heat pathogens; Concha Haliotidis is cold in nature, salty in the mouth is bitter, liver heat removing and eyesight improving; Cold in nature, the bitter in the mouth of Caulis Akebiae leads to heart lung heat clearing, rushes down wet diuresis; Cold in nature, the sweet and slightly bitter taste of Herba Dendrobii, foster lung makes eye bright; Warm in nature, the bitter in the mouth of Pollen Typhae is given birth to promoting the circulation of blood, ripe enrich blood, moisten logical; Warm in nature, the acrid in the mouth of Fructus Aurantii, circulation of qi promoting, remove to expand, the chest stuffiness relieving regulates the flow of vital energy; Warm in nature, the acrid in the mouth of Benzoinum, clear key, eliminating phlegm; Cold, the mildly bitter flavor of Borneolum Syntheticum, clearing away heat-fire.According to the pharmacology of above-mentioned various medicines as can be known, Semen Plantaginis, Cortex Phellodendri, Herba Dendrobii are walked kidney channel, and the eye blood capillary is had expansion mediation effect, meridians are had moist effect, and Concha Haliotidis have the power of opening; Radix Codonopsis, Poria energy spleen invigorating invigorating the spleen and replenishing QI, the capable then blood of gas is capable, the capable then manner of blood and smooth, sunlight is from Sheng; Pollen Typhae, Radix Notoginseng, Flos Carthami, Rhizoma Chuanxiong, warm in nature, the bitter in the mouth of Radix Angelicae Sinensis can nourish blood with blood, blood stasis dispelling, and ocular angiogenesis is abundant, so can be to having the eye meridians to have moist and yang-energy fills the Sheng effect; Radix Glycyrrhizae can be separated hundred poison, can relax the property of medicine; Benzoinum has the effect of having one's ideas straightened out; Fructus Aurantii can spleen invigorating, regulate the flow of vital energy, remove and expand, spleen hemopoietic, liver system blood, and the five internal organs link to each other, and spleen is useful to liver, and the liver being in charge of the eyes; Caulis Akebiae is useful to cardiopulmonary, and logical heart lung heat clearing then has manner sufficient, and sunlight is from the effect of containing; Flos Chrysanthemi, Herba Menthae, Borneolum Syntheticum can heat-clearing and toxic substances removing, make eye bright, and directly act on eye.The acupuncture point of human body circumference of eyes all with the human body twelve regular channels, 365 networks are relevant." Ling Shu Miraculous Pivot or Divine Axis greatly puzzled opinion " said: " the essence of five ZANG-organs and six FU-organs gas; annotate in order all, and smart for it, the eye being the nest of essence; the essence of the kidney manifesting in pupil; the essence of the liver manifesting in the black part of eye, the essence of the heart replenishing in the venules of eye, essence of its nest be the supercilious look; the essence of the spleen manifesting in the eyelids; pick the muscles and bones vim and vigour essence and with arteries and veins also for being, on belong to brain, after in the item " these born of the same parents' eyelid, two corners of the eyes, the supercilious look, black eye, five parts of pupil god of briefly having pointed out are corresponding with the five internal organs respectively.Ling Shu Miraculous Pivot or Divine Axis and for example, a pathogen cacosplanchnia shape piece of writing is said: " twelve regular channels, 365 networks, its vim and vigour all go up in face and walk the sky key, walk order on its vivid YANG QI and are smart ".From the relation that meridians communicate with internal organs, the twelve regular channels directly or indirectly has relation with eye, and this product is exactly by the smearing of circumference of eyes, and makes ion permeable substance, directly acts on eye, and presses down cloudy YANG invigorating, thereby reach the near-sighted purpose of treatment.

Good effect of the present invention is:

1, this eye ointment energy blood circulation promoting and blood stasis dispelling, expansion local vascular, blood flow increasing, microcirculation improvement.

2, this eye ointment energy dredge the meridian passage, having one's ideas straightened out makes eye bright; Regulate diopter, the spoke that strengthens eye muscle gathers power, impels the metabolism of ophthalmic, and by iontophoretic injection, directly replenishes required main nutrition and the trace element of eye.

The present invention is described in further detail below in conjunction with embodiment.

The first step, with 15 parts of Rhizoma Chuanxiongs, 20 parts of Radix Notoginseng, 15 parts of Concha Haliotidis, 10 parts on Flos Carthami, 20 parts of Herba Dendrobiis, 20 parts of Caulis Aristolochiae Manshuriensis, 15 parts of Cortex Phellodendris, 20 parts of Flos Chrysanthemis, 20 parts of Herba Menthaes, 12 parts of Pollen Typhaes, 12 parts in Radix Glycyrrhizae, 30 parts of Radix Angelicae Sinensis, 15 parts of Fructus Aurantiis, 15 parts of Semen Plantaginiss, 20 parts in Poria, 15 parts of Radix Codonopsis are removed impurity respectively, and oven dry is pulverized standby then.

15 parts of second step, the Concha Haliotidis after will pulverizing, 20 parts of Herba Dendrobiis, 20 parts of Caulis Aristolochiae Manshuriensis, 15 parts of Cortex Phellodendris are placed in the distilled water of 1500ml, with slow fire boiling 40 minutes, again with 15 parts of Rhizoma Chuanxiongs, 20 parts of Radix Notoginseng, 20 parts of Herba Menthaes, 10 parts on Flos Carthami decocted 30 minutes with slow fire in 20 parts of addings of Flos Chrysanthemi decoction liquor again, at last with 12 parts of Pollen Typhaes, 12 parts in Radix Glycyrrhizae, 30 parts of Radix Angelicae Sinensis, 15 parts of Fructus Aurantiis, 15 parts of Semen Plantaginiss, 20 parts in Poria, 15 parts of Radix Codonopsis add in the decoction liquor with slow fire and continue to decoct 20 minutes after-filtration, remove slag and be concentrated into 200 grams, are made as the A material.

The 3rd step, when the temperature of A material is reduced to 50-60 ℃, with 15 parts of Borneolum Syntheticums, 15 parts of Benzoinumes, medical ventolin joins in the A material for 300 parts and stirs, the eye ointment that are used for the treatment of myopia of 500 grams.

The effect observed result of this product is:

1, use all backs that 96 students' of experimental group distant vision is checked, the result shows that in 192 eyes observing, vision improves two row and reaches above 101 eyes that have, and accounts for and observes 52.60% of total eye number; Vision is constant has 84 eyes, accounts for to observe 43.75% of total eye number; Visual deterioration two row reach above 7 eyes that have, and account for to observe 3.65% of total eye number.In 92 eyes observing, have 26 eyes vision restoration to 5.0 and more than, account for and observe 13.54% of total eye number.

2, use after one month and 96 students' of experimental group distant vision checked once more the result shows that experimental group student's distant vision is significantly improved, with observe before compare, vision improves two row and above has 154 eyes, accounts for and observes 80.21% of total eye number; Vision is constant has 32 eyes, accounts for to observe 16.67% of total eye number.Visual deterioration two row reach above 6 eyes that have, and account for to observe 3.21% of total eye number.In 192 eyes observing, have 61 eyes vision restoration to 5.0 and more than, account for and observe 31.77% of total eye number.

3, the statistical test result shows, it is obvious different to use effect after one week of this product and January to have, and its difference has remarkable meaning (X ²(1)=34.40, P＜0.01.X ²(2)＝18.20，P＜0.01)。

4, use the effect of this product to be to the basic vision patient of difference, use after one month, its effect with the relation of different class basis vision is: 1. basic vision is 66 eyes that have of 4.9-4.7 (being low myopia), use this product after one month, vision is promoted has 50 eyes, accounts for 75.6%.Vision is constant has 15 eyes, accounts for 22.73%.Visual deterioration have 1 eye, account for 1.51%.Wherein have 38 eyes vision restoration to 5.0 and more than, account for and observe 57.58% of total eye number.2. basic vision is 85 eyes that have of 4.6-4.4 (being medium myopia), and uses this product after one month, and vision is promoted has 75 eyes, accounts for 88.24%.Vision is constant has 7 eyes, accounts for 8.24%.Visual deterioration have 2 eyes, account for 2.35%.Wherein have 23 eyes vision restoration to 5.0 and more than, account for and observe 27.06% of eye number.3. basic vision has 41 eyes for≤4.3 (being laser high myopia), uses this product after one month, and vision is promoted has 29 eyes, accounts for 70.73%.Vision is constant has 10 eyes, accounts for 24.39%.Visual deterioration have 3 eyes, account for 7.32%.Statistical test result shows that the student of different class basis vision uses the effect of this product that obvious difference is arranged, and its difference has remarkable meaning (X ²(1)=10.78, P＜0.05.X ²(2)＝40.24，P＜0.01)。

5, observe after one month, in 162 eyes of matched group, vision is promoted has 13 eyes, accounts for 8.02%.Vision is constant has 114 eyes, accounts for 70.37%.Visual deterioration have 35 eyes, account for 21.60%.Wherein have 10 eyes vision restoration to 5.0 and more than, account for and observe 6.17% of eye number.Compare with experimental group, highly significant difference (X is arranged ²(1)=184.40, X ²(2)=35.91, P＜0.01).

6, observed result shows, uses this product to correct student's pseudomyopia, and the effect in a week and month is all very obvious, and vision enhancement rate is respectively 52.60% and 80.21%.Basis vision difference uses the effect of this product that obvious difference is arranged, light, in, the laser high myopia patient use this product after one month vision enhancement rate be respectively 81.82%, 83.53% and 70.73%.

The using method of this product is to smear outside circumference of eyes skin, first cun of eyebrow to inferior orbit, inner eye corner to temple.Closed after smearing order 15-20 minute, and kept wiping again in 2 hours, every day three times, each 0.5-1.0g.

Claims (2)

1, a kind of eye ointment that is used to be used for the treatment of myopia is characterized in that it is made by following raw materials by weight percent, Rhizoma Chuanxiong 15, Radix Notoginseng 20, Concha Haliotidis 15, Flos Carthami 10, Herba Dendrobii 20, Caulis Aristolochiae Manshuriensis 20, Cortex Phellodendri 15, Flos Chrysanthemi 20, Herba Menthae 20, Pollen Typhae 12, Radix Glycyrrhizae 12,30 parts of Radix Angelicae Sinensis, Fructus Aurantii 15, Semen Plantaginis 15, Poria 20, Radix Codonopsis 15, Borneolum Syntheticum 15, Benzoinum 15, medical ventolin 300.

2, a kind of production technology of eye ointment as claimed in claim 1 is characterized in that, it comprises the following steps: the first step, with Rhizoma Chuanxiong 15, Radix Notoginseng 20, Concha Haliotidis 15, Flos Carthami 10, Herba Dendrobii 20, Caulis Aristolochiae Manshuriensis 20, Cortex Phellodendri 15, Flos Chrysanthemi 20, Herba Menthae 20, Pollen Typhae 12, Radix Glycyrrhizae 12, Radix Angelicae Sinensis 30, Fructus Aurantii 15, Semen Plantaginis 15, Poria 20, Radix Codonopsis 15 is removed impurity respectively, and oven dry is pulverized standby then;

Second step, the Concha Haliotidis 15 after will pulverizing, Herba Dendrobii 20, Caulis Aristolochiae Manshuriensis 20, Cortex Phellodendri 15 is placed in the distilled water of 1500ml, with slow fire boiling 40 minutes, again with Rhizoma Chuanxiong 15, Radix Notoginseng 20, Herba Menthae 20, Flos Carthami 10, decocted again 30 minutes with slow fire in the Flos Chrysanthemi 20 adding decoction liquor, at last with Pollen Typhae 12, Radix Glycyrrhizae 12, Radix Angelicae Sinensis 30, Fructus Aurantii 15, Semen Plantaginis 15, Poria 20, Radix Codonopsis 15 add in the decoction liquor with slow fire and continue to decoct 20 minutes after-filtration, remove slag and be concentrated into 200 grams, are made as the A material;

The 3rd step, when the temperature of A material is reduced to 50-60 ℃, with Borneolum Syntheticum 15, Benzoinum 15, medical ventolin 300 join in the A material and stir.