CN1270710C - Medicinal solution for treating ulceration and inflammation - Google Patents
Medicinal solution for treating ulceration and inflammation Download PDFInfo
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- CN1270710C CN1270710C CN 200410064571 CN200410064571A CN1270710C CN 1270710 C CN1270710 C CN 1270710C CN 200410064571 CN200410064571 CN 200410064571 CN 200410064571 A CN200410064571 A CN 200410064571A CN 1270710 C CN1270710 C CN 1270710C
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- metronidazole
- medicine solution
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Abstract
The present invention relates to an external medicine for treating dermatosis and oral ulcers. Every 10000 ml of medicine solution is prepared from the following components: 150 to 200g of zinc gluconate, 20 to 30g of metronidazole (fossyol), 61 to 2g of vitamin B, 5 to 10g of tetracaine and 10 to 15g of sodium benzoate. The medicine solution of the present invention relieves inflammation, resists infection, repairs and protects skin mucosa, carries out convergence, relieves pain and itching and promotes wounds to be repaired and healed. The medicine solution of the present invention is suitable for obdurate and recurrent oral ulcers, has obvious effect, prevents relapse and has favorable curative effect on various obstinate skin diseases, such as pruritus, eczema, neurodermatitis, acne, wound, etc.
Description
Technical field
The present invention relates to a kind of external used medicine solution for the treatment of dermatosis and oral ulcer.
Technical background
The oral ulcer and the various dermatosis chronic disease that have intractable, recurrent at present, all kinds of skin infection sexually transmitted disease (STD)s changes have a strong impact on people's physical and mental health as skin pruritus, eczema, urticaria, dermatitis, acne and decubital ulcer etc., people take multiple medicine and medical procedure treatment, but effect is all not very good.
Summary of the invention
Technical problem to be solved by this invention provides a kind of have good and clinical curative effect and nontoxic, side effect and the treatment dermatosis of drug dependence and the external used medicine solution of oral ulcer.
The present invention adopts following technical scheme: contain following composition by weight in the 10000ml drug solution of the present invention:
Zinc gluconate 150-200g metronidazole (metronidazole) 20-30g
Vitamin B6 1-2g tetracaine 5-10g sodium benzoate 10-15g
Surplus is a water.
The preparation method of solution of the present invention is for adopting following composition by weight:
Zinc gluconate 150-200g metronidazole (metronidazole) 20-30g
Vitamin B6 1-2g tetracaine 5-10g sodium benzoate 10-15g
Above-mentioned component is processed into adds water after powder mixes and make 10000ml solution, precipitate after-filtration, sterilization, packing in 24 hours and promptly make.
The present invention is Main Ingredients and Appearance with the zinc gluconate, and pharmacodynamic experiment proves that organic zinc absorbs ideal can bring into play curative effect fast, experiment confirm zinc deficiency oral mucosa hypertrophy parakeratosis, and zinc deficiency blocks taste pore, and the oxygeusia degree is reduced; Zinc deficiency has reduced the vigor of hydroxyl PEPA A, and digestive function is obviously descended.Zinc has the reparation of acceleration, promotes the normal skin cutin to generate, and powerful convergence is arranged, and effect antipruritic, analgesia is arranged, and can promote the healing and the rehabilitation of pathological changes such as skin ulcer, wound, eczema, and the skin drag of enhancing and autoimmune powerful effect are arranged.
Be higher than oral once amount through experiment confirm and clinical observation zinc gluconate, the aqueous solution external safety of one times of content does not have any toxicity, side effect.The zinc gluconate powder that the present invention adopts is that state-run regular pharmaceutical factory produces, the sufficient price lower (about 1000 yuan of every Kg) in medicine source.And this raw material medicine all meets the medicine inspection acceptable quality level.Manufacturing condition of the present invention requires clear and definite, and technological process is simple, and system is joined technical operation and easily grasped, but medicament compartment equal ordinary production in general pharmaceutical factory does not need the sharp equipment of special height.
Drug solution antiinflammatory infection of the present invention, restoration and protection skin mucosa, restrain, relieve the pain, antipruritic short repair in trauma healing.Drug solution of the present invention is applicable to intractable, recurrent oral ulceration, and produce effects speed, anti-recurrence, to various dermatosis chronic diseases all have curative effect preferably as skin itching disease, eczema, neurodermatitis, acne and wound etc.Drug solution of the present invention contain cough, affected part is embrocated, soak all can.The present invention is an aqua, and every bottle of 100ml seals, puts shady and cool place and preserves, and storage life is 2 years.Because drug solution of the present invention (prove effective fast, late result is high, relapse rate is low) evident in efficacy therapeutic domain is wider, is higher than other like products and nontoxic, side effect through clinical verification curative effect for many years.Colorless and odorless easy to use does not stain medicated clothing.And medicine source abundance, with low cost, preparation does not simply need high investment, can obtain remarkable society and economic benefit.Event is clinical and market prospect is very optimistic.
The clinical observation on the therapeutic effect table:
Subordinate list 1 is treatment recurrent, intractable oral cavity ulcer.
Systematic observation 70 examples, wherein the child accounts for 78%, and all with symptoms such as the different malnutrition of degree, immunologic hypofunction, monophagia, anorexia, different foods.Healing person's 59 examples (accounting for 84.3%) after the week after medication, produce effects 11 example points 15.7%, total effective rate reaches 100%.
Table 1:
Subordinate list 2 is to several dermatosis observation of curative effect
Observe 153 routine skin cases altogether, wherein have acne, skin pruritus, eczema, decubital ulcer evident in efficacy.Curative effect sees Table 2:
Vitiligo, psoriasis then curative effect are not good enough.
Table 2:
| The example number | Take a turn for the better (routine %) | Cure (routine %) | Invalid (routine %) | Total effective rate | |
| Acne | 26 | 3 | 22 | 1 | 96％ |
| Skin itching | 32 | 4 | 28 | 0 | 100％ |
| Eczema | 18 | 4 | 14 | 0 | 100％ |
| Neural dermatitis | 16 | 0 | 16 | 0 | 100％ |
| The spirit measles | 14 | 3 | 10 | 1 | 93％ |
| Decubital ulcer | 24 | 0 | 24 | 0 | 100％ |
| Psoriasis | 9 | 5 | 0 | 4 | 55％ |
| Vitiligo | 14 | 3 | 0 | 11 | 21.4％ |
| Amount to | 153 | 22(14.4％) | 114(74.5％) | 17(11.1％) | 88.8％ |
The specific embodiment
The embodiment of the invention is as shown in table 3, contains following composition by weight in the 10000ml drug solution of the present invention:
Table 3:
| Composition | Content (weight g) | ||
| Zinc gluconate | 150 | 175 | 200 |
| Metronidazole (metronidazole) | 25 | 30 | 20 |
| Vitamin B6 | 1 | 1.5 | 2 |
| Tetracaine | 7.5 | 5 | 10 |
| Sodium benzoate | 10 | 12.5 | 15 |
Claims (1)
1, a kind of external used medicine solution for the treatment of dermatosis and oral ulcer is characterized in that containing in the 10000ml drug solution following composition by weight:
Zinc gluconate 150-200g metronidazole (metronidazole) 20-30g
Vitamin B6 1-2g tetracaine 5-10g sodium benzoate 10-15g
Surplus is a water.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410064571 CN1270710C (en) | 2004-11-30 | 2004-11-30 | Medicinal solution for treating ulceration and inflammation |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 200410064571 CN1270710C (en) | 2004-11-30 | 2004-11-30 | Medicinal solution for treating ulceration and inflammation |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1650861A CN1650861A (en) | 2005-08-10 |
| CN1270710C true CN1270710C (en) | 2006-08-23 |
Family
ID=34868852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 200410064571 Expired - Fee Related CN1270710C (en) | 2004-11-30 | 2004-11-30 | Medicinal solution for treating ulceration and inflammation |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1270710C (en) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4799957B2 (en) * | 2005-08-23 | 2011-10-26 | 興和株式会社 | Pharmaceutical composition for the treatment of stomatitis |
| FR2899475A1 (en) * | 2006-04-10 | 2007-10-12 | Galderma Res & Dev | Composition, useful to prepare a drug to treat and/or the prevent rosacea, preferably vascular disorders caused by rosacea, comprises metronidazole and zinc, in a medium |
| CN105748516A (en) * | 2016-03-30 | 2016-07-13 | 黄宇松 | Pharmaceutical composition for treating repeated oral ulcers |
-
2004
- 2004-11-30 CN CN 200410064571 patent/CN1270710C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1650861A (en) | 2005-08-10 |
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| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C17 | Cessation of patent right | ||
| CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20060823 Termination date: 20091230 |