CN1270694C - Toothpaste containing extract from Chinese traditional medicine as well as preparing method and application - Google Patents
Toothpaste containing extract from Chinese traditional medicine as well as preparing method and application Download PDFInfo
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Abstract
The present invention relates to toothpaste containing extracts from Chinese traditional medicine, particularly toothpaste with extracts from tulip Chinese traditional medicine, a preparation method and application for whitening and cleaning teeth. Addition quantity which can be used as extracts from the Chinese traditional medicine of tulip administration is 0.1% to 10% of the total quantity of the toothpaste. Each extract from the Chinese traditional medicine is especially suitable for removing smoke spots and tea spots. A toothpaste product made by the extract has the advantages of light appearance color, stable production quality and obvious effects on cleaning and whitening the teeth.
Description
Technical field
The present invention relates to a kind of toothpaste that contains Chinese medicine extract, especially contain the toothpaste of Radix Curcumae class Chinese medicine extract, and preparation method thereof and the application of whitening and cleaning the teeth.
Background technology
Tooth is the organ that body weight for humans is wanted, and tooth pure white, health is one of sign of health, smoking, drink coffee, fruit juice easily causes xanthodont, black tooth.Oxalates in tar, theophylline, pigment and the food detritus, the combination of antibacterial secretions, be attached on the dental plaque, slowly pile up and form black, xanchromatic schmutzband at dental surface, and prolong in time, more and more firm, common toothpaste is brushed teeth and is difficult for brushing away, and has had a strong impact on the attractive in appearance and healthy of tooth.The existing method for whitening that cleans the teeth, product is many, but easy to use, good effect, better quality products at good values and method are few.As the chemical bleaching method; utilize the chemical bleaching agent, as concentrated hydrochloric acid, hydrogenperoxide steam generator; urea peroxide; though the energy bleaching teeth needs the strict consumption of grasping when using, action need is conscientiously careful; prevent to corrode; the injury oral mucosa, tissue often uses the protective layer to dental surface to have bigger infringement.And medical institutions' conventional machinery friction toothwash, need professional's operation, time-consuming, valency is expensive, inconvenient, the simplest and commonly used method is to use whitening toothpaste, and great majority clean the teeth whitening toothpaste mainly by adding abrasive, as calcium carbonate, aluminium hydroxide, silicon dioxide etc., utilize the friction between tooth and polishing particles, dispel tartar.Want to remove smoking patch, tea speckle by friction, particle that will zone of preference certain angle structure is as calcium carbonate, can be observed at microscopically has obvious scuffing to dental surface, and the selection round particle, it is better to remove food detritus effect, but removes smoking patch, tea speckle DeGrain.Also there are some products to make up and eliminate smoking patch, tea speckle from chemolysis agent, the dirty agent of dispelling, abrasive, the several aspects of antibacterial.Along with improving constantly of people's living standard, pursue healthy, return natural, natural plant type health promoting product increased popularity, various Chinese herbal toothpastes, dentifrice constantly appears on the market, various Chinese herbal medicine oral preparations are developed out, and at removing smoking patch, the tea speckle, the toothpaste of pigmented spots, dentifrice is also few, even have, as patent publication No. CN1084738A, CN1104481A, CN1146333A, CN1243700A, CN1072841A, CN1181235A, these patented products all are Chinese medicine compound, the extract color is dark, be sepia or pale brown color, in recent years, data has been reported Rhizoma Polygoni Cuspidati, Rhizoma Coptidis, Fructus Schisandrae Chinensis, to streptococcic antibacterial action, to smoking patch, the elimination of tea speckle plays synergism, but the extract color of above-mentioned medical material is dark, technology before, product is often paid attention to curative effect and is ignored the appearance luster of product and the commercial value of product.The toothpaste made of brownish black, brown xanchromatic Chinese medicine extract particularly, the mastic of extruding is ugly, after brushing several times tooth, the fleece Chinese medicine of toothbrush is caught color, consumer throws doubt upon to the whitening effect of the smoking patch of dispelling of product, tea speckle, pigmented spots, seriously restrict the sale of product, influenced image product.And take to remove color technology, and increase cost on the one hand, also often reduce whitening effect on the other hand.
Summary of the invention
The object of the present invention is to provide a kind of toothpaste that contains Chinese medicine extract.
Another object of the present invention provides a kind of preparation method that contains the toothpaste of Chinese medicine extract.
Another object of the present invention provides a kind of toothpaste that contains Chinese medicine extract in the application of whitening aspect cleaning the teeth, and specifically is removing speckle, particularly removing application in the smoking patch tea speckle.
Another object of the present invention is simultaneously also to provide this Chinese medicine extract in the application of whitening aspect cleaning the teeth, and specifically is removing speckle, particularly removing application in the smoking patch tea speckle.
Technical scheme of the present invention is:
A kind of toothpaste that contains Chinese medicine extract, this Chinese medicine extract are RADIX CURCUMAE from Sichuan of China, RADIX CURCUMAE, Guangxi zedoary, in the extract of Rhizoma Curcumae any one or several.
The toothpaste that contains Chinese medicine extract, this Chinese medicine extract are single RADIX CURCUMAE from Sichuan of China extract.
The toothpaste that contains Chinese medicine extract, this Chinese medicine extract are RADIX CURCUMAE from Sichuan of China, the mixed extract of Guangxi zedoary.
The toothpaste that contains Chinese medicine extract, this Chinese medicine extract are the mixed extract of RADIX CURCUMAE from Sichuan of China, RADIX CURCUMAE, Guangxi zedoary.
The toothpaste that contains Chinese medicine extract, this Chinese medicine extract are the mixed extract of RADIX CURCUMAE from Sichuan of China, RADIX CURCUMAE, Rhizoma Curcumae.
The toothpaste that contains Chinese medicine extract, the addition of Chinese medicine extract are the 0.1-10% of toothpaste gross weight.
The toothpaste that contains Chinese medicine extract, the addition of Chinese medicine extract are the 1-8% of toothpaste gross weight.
The preparation method that contains the toothpaste of Chinese medicine extract, the preparation method that Chinese medicine extract adopts is: RADIX CURCUMAE from Sichuan of China, RADIX CURCUMAE, Guangxi zedoary, in the Rhizoma Curcumae any one or several raw medicinal material are ground into coarse powder, add 60-75% alcohol reflux secondary, 2 hours for the first time, 8 times of amount ethanol, 1.5 hours for the second time, 6 times of amount ethanol, filtration, filtrate recycling ethanol and to be concentrated into relative density be 1.06-1.08, spray drying gets the Chinese medicine extract of dry powder; The conventional base material mix homogeneously of Chinese medicine extract and toothpaste is made toothpaste.
The toothpaste that contains Chinese medicine extract, this Chinese medicine extract is 3.0 kilograms of single RADIX CURCUMAE from Sichuan of China extracts, and all the other compositions of its toothpaste and prescription are 20 kilograms of sorbitol, 20 kilograms of calcium carbonate, 8.0 kilograms of silicon dioxide, 0.8 kilogram of titanium dioxide, 0.5 kilogram of xanthan gum, 1.5 kilograms of sodium lauryl sulphates, 0.2 kilogram of sodium benzoate, 0.1 kilogram of saccharin sodium, 0.2 kilogram in essence, 45.7 kilograms in water.
Contain the application of whitening and cleaning the teeth of the toothpaste of Chinese medicine extract.
The toothpaste that contains Chinese medicine extract is in the application of whitening aspect cleaning the teeth, and specifically is removing speckle, particularly removing application in the smoking patch tea speckle.The Chinese medicine extract medical material that the present invention uses is zingiberaceous plant, its Chinese and English are specially RADIX CURCUMAE from Sichuan of China Curcuma Chuan Yujinc.k.Hsiehet H.Zhang or Curcuma aromatica salisb, RADIX CURCUMAE Curcuma Wen Yujin Y.H.chenet.Ling, Guangxi zedoary CurcumaKwangsiensiss.g.Leetc.F.Liang or Rhizoma Curcumae Curcuma Phaeocaulis Val.
In order to screen more excellent technical scheme, select for use the multiple medical material of Radix Curcumae to carry out many-sided experiment.
One, selects the be used as medicine functional comparison of method of different medical materials for use
1, different medical materials are gone into the color comparison that medicament extract is made toothpaste
1 kilogram of No. 1 medical material RADIX CURCUMAE from Sichuan of China, 1 kilogram of No. 2 medical material RADIX CURCUMAE, 1 kilogram of No. 3 medical material Guangxi zedoary, 0.5 kilogram of No. 4 medical material RADIX CURCUMAE from Sichuan of China, 0.5 kilogram of RADIX CURCUMAE, 0.5 kilogram of No. 5 medical material RADIX CURCUMAE from Sichuan of China, 0.5 kilogram of Guangxi zedoary, 0.5 kilogram of No. 6 RADIX CURCUMAE from Sichuan of China, 0.5 kilogram of Rhizoma Curcumae, 0.4 kilogram of No. 7 medical material RADIX CURCUMAE from Sichuan of China, 0.3 kilogram of RADIX CURCUMAE, 0.3 kilogram of Guangxi zedoary, 0.4 kilogram of No. 8 medical material RADIX CURCUMAE from Sichuan of China, 0.3 kilogram of RADIX CURCUMAE, 0.3 kilogram of Guangxi zedoary.
Extracting method: per 1 kilogram of medical material, add 65% alcohol reflux secondary, 8 kilograms for the first time, 2 hours, 6 kilograms for the second time, 1.5 hours, filter, filtrate recycling ethanol is concentrated into 1.06-1.08, and spray drying gets dry powder.
1 to No. 8 medical material obtains dry powder with above-mentioned extracting method respectively, and the addition by 2% adds dry powder and makes toothpaste, and relatively 8 kinds of extracts make the lotion of toothpaste color and luster, with adding Chinese white, the method of titanium dioxide makes the mastic color and luster as far as possible near the color that does not add Chinese medicine, and the result is as follows;
Table 1
| Select medical material for use | No. 1 | No. 2 | No. 3 | No. 4 | No. 5 | No. 6 | No. 7 | No. 8 |
| RADIX CURCUMAE from Sichuan of China | RADIX CURCUMAE | Guangxi zedoary | RADIX CURCUMAE from Sichuan of China+RADIX CURCUMAE | The river is gold+Guangxi zedoary all | RADIX CURCUMAE from Sichuan of China+RADIX CURCUMAE+Guangxi zedoary | The river is gold+Rhizoma Curcumae all | RADIX CURCUMAE from Sichuan of China+Wen Doujin+Rhizoma Curcumae | |
| The titanium dioxide addition | 0.5％ | 1.5％ | 1.0％ | 1.2％ | 0.8％ | 1.1％ | 0.9％ | 1.2％ |
| Color and luster | In white yellow is arranged slightly | Band light brown in white | In white yellow is arranged slightly | Be with shallow sepia in white | Be with light yellow in white | Have shallow sepia in white | Be with light yellow in white | Have shallow sepia in white |
Result: every common turmeric extract, lotion of toothpaste color and luster difficulty is adjusted to white, and the common turmeric extract color is sepia, promptly uses mastic color and luster when relatively large white pigments accent is also inaccessibility not to add Chinese medicine, first-selected scheme is a RADIX CURCUMAE from Sichuan of China list usefulness, and secondly RADIX CURCUMAE from Sichuan of China and Guangxi zedoary or Rhizoma Curcumae are used with.
The present invention simultaneously also provides this Chinese medicine extract in the application of whitening aspect cleaning the teeth, and specifically is removing speckle, particularly removing application in the smoking patch tea speckle.
The invention has the advantages that:
The extract of Chinese medicine Radix Curcumae class plant experimental results demonstrate new function except that smoking patch, tea speckle through the present invention, can be used as the medical material that Radix Curcumae is used as medicine is a kind of or blended RADIX CURCUMAE from Sichuan of China, RADIX CURCUMAE, Guangxi zedoary or Rhizoma Curcumae, this Radix Curcumae class medicinal substances extract adds in the toothpaste as toothpaste additive, the effect that toothpaste is had clean the teeth and whiten, the tooth paste product that Chinese medicine extract of the present invention makes, appearance luster is light, constant product quality, and the whitening effect that cleans the teeth is obvious.The preparation method that contains the toothpaste of Chinese medicine extract of the present invention, technology is simple, and is easy to operate.The present invention considers from the commercial operation of product, with the curative effect of medication is foundation, by a large amount of foliage filter screenings, it is stable to obtain chemical property, the Chinese medicine extract that color and luster is light joins in the toothpaste, color has improved the commercial value of this patent product widely near white, faint yellow, and the product appearance of making is good.
The present invention is thick, big, a black phenomenon of avoiding the medication of Chinese medicine compound recipe, guaranteeing to remove under the prerequisite of smoking patch, tea speckle effect, screen folk prescription and little compound recipe medication, and according to effect, the stability of extract, color and luster, cost are taken all factors into consideration and are filtered out the Radix Curcumae class, in extraction and preparation technique, adopt spray drying process, shorten concentration time, reduce the color and luster of extract color.
Key of the present invention is a screening Chinese medicine medical material kind, extract is added in the toothpaste, the mastic color and luster is adjustable near white or yellowish white, joins in toothpaste, tooth-cleaning powder, the oral cavity cleaning glue, makes the color and luster when product color is approaching does not as far as possible add Chinese medicine extract.According to People's Republic of China's version pharmacopeia in 2000,166 pages of Radix Curcumae medical materials are used as medicine and can be RADIX CURCUMAE, Rhizoma Curcumae Longae, the dried root of Guangxi zedoary or Rhizoma Curcumae, the present invention does not select the Rhizoma Curcumae Longae medical material for use, be because Rhizoma Curcumae Longae contains higher curcumin, this pigment dyeing ability is strong, when Rhizoma Curcumae Longae extract joins in the toothpaste, in using the toothpaste process after continuous three days, pigment can be dyed yellowish-brown to bristles, although can make firm smoking patch, the tea speckle is loosening, with brushing teeth and brush down gradually, but curcumin makes the white tooth that exposes also catch yellow simultaneously, not only reduce whitening effect,, be difficult to obtain the trust of consumer also for the sale of product brings great inconvenience.
Chinese medicine medical material of the present invention has increased Curcuma aromatica salisb Radix Curcumae kind by name, 2218 pages of 1316 pages of the Chinese medicine voluminous dictionary first volumes and the Chinese herbal first volumes, all put down in writing this medical material kind of RADIX CURCUMAE from Sichuan of China, increase this kind medical material and be because it to contain pigment few, remove smoking patch, tea speckle effect is not obviously distinguished with RADIX CURCUMAE, Guangxi zedoary.Guangxi zedoary, common turmeric extract color are darker, join the titanium dioxide toning that needs in the product with more, just can reach near white, at present on the Chinese Medicinal Materials Markets, when buying the Radix Curcumae medical material, there are two 3 kinds to mix often, the medical material kind that the present invention selectes as the Radix Curcumae use, dispel the not significantly difference of smoking patch, tea speckle effect, so when medical material is selected for use, consider the convenience of production, and the practical situation of medical material market medical material, the medical material that the medical material that mixes can be used as extract preparation of the present invention uses.
Other gets 1 kilogram of medical material of Rhizoma Curcumae Longae
Extracting method: per 1 kilogram of medical material, add water 65% alcohol reflux secondary, 8 kilograms for the first time, 2 hours, 6 kilograms for the second time, 1.5 hours, filter, filtrate recycling ethanol is concentrated into 1.06-1.08, and spray drying gets Rhizoma Curcumae Longae extract dry powder.
Addition by 2% adds Rhizoma Curcumae Longae extract dry powder in the toothpaste to, similarity condition by table 1 is done control experiment, observe the lotion of toothpaste color and luster that extract makes, observation shows with the method for adding white pigment titanium dioxide can't make lotion of toothpaste reach near white, can't make the mastic color and luster as far as possible near the color that does not add Chinese medicine.
Add the result and show the lotion of toothpaste that contains 2% Rhizoma Curcumae Longae extract under the state that adds titanium dioxide 1%, color is brown, add under the state of titanium dioxide 3% still to be light brown, but the toothpaste color still partially deeply, influences attractive in appearancely, and commercial value is low.
2, tea patch test
The tooth hydrogen peroxide bleaching will exsomatize, tooth after the bleaching is dipped in 37 ℃, in the mixed liquor of forming by tea, saliva, to the dental surface flavescence, the tooth of flavescence joins in the solution that contains 2% extract, soaked 1 hour, and observed No. 1 to No. 8 eight kinds of extracts and make the not obviously difference of the thin out effect of color of teeth.
3,8 kinds of extracts remove the experiment of smoking patch effect:
Get eight plate glass pieces, fixedly be placed on the plane of desktop sustained height, 10cm place below every block of glass, respectively light one with the medicated cigarette in the deck, form smoking patch, coat the long mastic that contains 1,2,3,4,5,6,7, No. 8 toothpaste of 1cm respectively, from verso view smoking patch diffusion velocity, the not obviously difference of range size of glass plate.
By removing smoking patch, tea speckle, 8 kinds of medical material selecting methods of toothpaste color and luster description of test do not have significant difference on effect, on product attractive in appearance obvious difference are arranged, and should select color and luster light, to improve the commercial value of product, make things convenient for marketing.
Two, the optimization experiment of method for preparing extractive
Compare five kinds of toothpaste that extracting method makes, the depth of pale brown color relatively wherein is used as medicine with RADIX CURCUMAE from Sichuan of China, each half mixing of RADIX CURCUMAE, and every toothpaste contains crude drug 20g.
1, the medical material water decocts secondary, filters, and filtrate economic benefits and social benefits thin film concentration is to relative density 1.06-1.08, and spray drying gets dry powder.
2, the preparation method of Chinese medicine extract is: medical material decocting in water secondary, filter, and be concentrated into relative density 1.1, add ethanol and make and contain the alcohol amount and reach 60-75%, reclaim ethanol, concentrating under reduced pressure gets extractum.
3, medical material filters with 65% alcohol reflux secondary, reclaims ethanol, and the concentrated solution spray drying gets dry powder.
4, medical material adds water and extracts volatile oil with steam distillation; Medicinal residues slag water decocts twice, filters, and to relative density 1.06-1.08, spray drying gets dry powder to filtrate with the economic benefits and social benefits thin film concentration, and extract is volatile oil and dry powder.
5, medical material adds water and extracts volatile oil with steam distillation; Medicinal residues slag water decocts twice, filters, and filtrate, adds ethanol and makes and contain the alcohol amount and reach 60-75% to relative density 1.08-1.10 with the economic benefits and social benefits thin film concentration, leaves standstill, and filters, reclaims ethanol, and the extractum of solution for vacuum concentration to 1.28, extract are volatile oil, extractum.
Table 2
| Extracting method | No. 1 | No. 2 | No. 3 | No. 4 | No. 5 |
| Pale brown color depth | ++ | ++ | + | +++ | ++++ |
From comparative result as can be seen, No. 4, No. 5 schemes, the color of volatile oil and extract volatile oil after medicinal residues to extract the toothpaste color that the extract that obtains makes again dark partially.No. 2 scheme adopts decoction and alcohol sedimentation technique, because precipitate with ethanol is removed impurity, the time shortens, and the toothpaste color and luster is thin out.No. 3 schemes, further shorten heat time heating time, and the 60-75% ethanol extraction has been removed a part of impurity, and the toothpaste color and luster is lighter, and No. 3 scheme technology is simple, and the medical material heated time is short, and the extract color and luster is good.
Five kinds of extract dissolving smoking patch ability comparisons that extracting method makes:
Five kinds of extracts are made 5 kinds of toothpaste respectively, and every toothpaste contains the medical material amount and equates, lights at the place with Linear Leaf Speedwell cigarette 10cm under distance glass respectively on five plate glass pieces, cause smoking patch, coat the long mastic of 1cm, after 5 minutes, move mastic 10 times with toothbrush, the bristle of toothbrush does not directly contact smoking patch.
Table 3
| Extraction scheme | 1 | 2 | 3 | 4 | 5 |
| The smoking patch dissolving relatively | 1/5th | 1/4th | 1/4th | 1/3rd | 1/3rd |
Water washes out mastic, and remaining smoking patch on the glass plate what are observed.
From the experiment of dissolving smoking patch, can know that water-soluble components is an active substance, No. 4, No. 5 schemes have influenced the diffusion of tar because volatile oil is arranged.
The tea patch test of the extract that five kinds of extracting method make.
The tooth hydrogen peroxide bleaching that will exsomatize is dipped in 37 ℃ with the tooth after the bleaching, and in the mixed liquor of being made up of tea, saliva, to the dental surface flavescence, the tooth of flavescence joins in the solution that contains 2% extract, soaks 1 hour.Observe the color ability of removing of 1-5 extraction scheme.
Table 4
| Extraction scheme | 1 | 2 | 3 | 4 | 5 |
| Remove the color ability | ++ | + | ++ | + | + |
The result shows that volatile oil has influenced and removed color, and water-soluble substances is effective.
Streptococcus is tested the tooth adhesiveness:
Streptococcus is the main bacteria seed of bacterial plaque, and it sticks on the tooth, forms bacterial plaque, impels crock, tea stain to form mixed stain, and making is difficult to brush teeth with ordinary toothpaste removes, and reduces the adhesion of streptococcus to tooth, can strengthen except that the speckle effect.
The tooth that will exsomatize cuts into the thin slice bleaching, adds five kinds of extracts of identical crude drug amount in five parts of bacteria culture bottles respectively, adds bacterium liquid behind the medium sterilization, and after taking-up was handled after 48h hour, how much streptococcic electron-microscope scanning was observed.
Table 5
| Extraction scheme | 1 | 2 | 3 | 4 | 5 |
| The electron-microscope scanning streptococcus intermedius how much | +++ | ++ | + | + | + |
The result shows that volatile oil, ethanol extract can significantly reduce streptococcic adhesiveness.
Experimental results show that from above, water-soluble components has certain dissolution to tea stain, crock and fat-soluble composition has stronger effect to bacterial plaque, so extraction process will consider that the two takes into account, ethanol extraction with 60-70%, and consider from product appearance color and luster aspect, reduce heated time as far as possible, adopt alcohol reflux, spray drying can both shorten heated time.And volatile oil has antibiotic property, can reduce the adhesiveness of streptococcus on tooth oral cavity bacterium such as streptococcus, but the color of volatile oil influences the aesthetic property of lotion of toothpaste, and the diffusion velocity of smoking patch in lotion of toothpaste, so do not adopt the technology of extracting volatile oil.
Further specify below in conjunction with embodiment.
The specific embodiment
Embodiment 1:
Use medical material: 100 kilograms of RADIX CURCUMAE from Sichuan of China.
The Chinese medicine extract preparation method: Chinese crude drug is with 65% alcohol reflux secondary, 8 times of amounts, 2 hours for the first time, and 6 times of amounts, 1.5 hours for the second time, filtration, filtrate recycling ethanol is concentrated into relative density 1.06-1.10, and spray drying gets dry powder.
Prescription: feed intake by 100 kilograms of toothpaste:
Get 20 kilograms of sorbitol, 1.2 kilograms of sodium fluoride, 20 kilograms of calcium carbonate, 8.0 kilograms of silicon dioxide, 0.8 kilogram of titanium dioxide, 0.5 kilogram of xanthan gum, 1.5 kilograms of sodium lauryl sulphates, 0.2 kilogram of sodium benzoate, 0.1 kilogram of saccharin sodium, 0.2 kilogram in essence, 44.5 kilograms in water is as the toothpaste base material.Get 3.0 kilograms of Chinese medicine extract and mix with the toothpaste base material, toothpaste technology is made the toothpaste that can clean the teeth and whiten routinely.
Clinic trial:
The object that tries totally 103 people, the range of age 22-58 year, male 83 people wherein, women 20 people, people's smoking of 68%, 56% people has tea, the trier respectively brushes teeth once every day sooner or later, around using continuously, uses front and back facing pigment exponential sum gingival index situation relative analysis by surgeon dentist inspection user oral hygiene situation, what facing pigment index reflected is dental surface pigmentation situation, index is big more, and the facing pigment is many more, and what gingival index reflected is red swelling of gingiva, hemorrhage, oral hygiene situations such as tartar, gingival index is high more, and the oral hygiene situation is poor more.76% trier thinks that using backteeth complexion element to deposit reduces, and facing bleaches before using, and result on trial is as follows:
Back on probation pigment index variation
Table 6
| Sex | The example number | Index before on probation | Back on probation index |
| The male | 83 | 1.79 | 1.19 |
| The women | 20 | 1.13 | 0.78 |
| Add up to | 103 | 3.29 | 1.97 |
Back on probation gingiva index variation
Table 7
| Sex | The example number | Index before on probation | Back on probation index |
| The male | 83 | 1.81 | 1.52 |
| The women | 20 | 1.36 | 1.13 |
| Add up to | 103 | 2.94 | 2.65 |
Clinic trial result proves that the toothpaste that this extract is made has reduced facing pigment exponential sum gingival index significantly, improves the oral hygiene situation, makes smoking, the pigment that forms of having tea has tangible desalination.
Embodiment 2
Use medical material: 50 kilograms of RADIX CURCUMAE from Sichuan of China, 50 kilograms of RADIX CURCUMAE, Chinese medicine extract preparation method and toothpaste production method are with embodiment 1.
Embodiment 3
The use medical material is formed: 50 kilograms of RADIX CURCUMAE from Sichuan of China, 50 kilograms of Guangxi zedoaries, Chinese medicine extract preparation method and toothpaste production method are with embodiment 1.
Embodiment 4
The use medical material is formed: 50 kilograms of RADIX CURCUMAE from Sichuan of China, and 50 kilograms of Rhizoma Curcumae, Chinese medicine extract preparation method and toothpaste production method are with embodiment 1.
Embodiment 5
The use medical material is formed: 40 kilograms of RADIX CURCUMAE from Sichuan of China, 30 kilograms of RADIX CURCUMAE, 30 kilograms of Guangxi zedoaries.Chinese medicine extract preparation method and toothpaste production method are with embodiment 1.
Embodiment 6
The use medical material is formed: 40 kilograms of RADIX CURCUMAE from Sichuan of China, 30 kilograms of RADIX CURCUMAE, 30 kilograms of Rhizoma Curcumae.The Chinese medicine extract preparation method is with embodiment 1.
Embodiment 7
Whiten to clean the teeth for one group and can remove the toothpaste of smoking patch tea speckle:
Table 8
| (A composite formula) | (B composite formula) | ||
| The precipitated silica grinding agent | 20％ | Silicon dioxide | 20％ |
| Sorbitol | 30％ | Sorbitol | 40％ |
| Glycerol | 18％ | Sodium lauryl sulfate | 1.5％ |
| HANSHENGJIAO | 0.5％ | Dodecylbenzene sodium sulfonate | 0.5％ |
| Polyacrylate (940) | 0.25％ | HANSHENGJIAO | 0.5％ |
| Sodium lauryl sulfate | 1.2％ | Sodium fluoride | 0.2％ |
| Sodium fluoride | 0.3％ | Titanium dioxide | 1.0％ |
| Saccharin sodium | 0.1％ | Saccharin sodium | 0.2％ |
| Biphosphate | 0.6％ | Polyethylene Glycol (1500) | 3％ |
| Titanium dioxide | 0.8％ | Tetrasodium pyrophosphate | 2.5％ |
| Chinese medicine extract | Some | Chinese medical concrete | Some |
| The water of surplus | The water of surplus |
(1) makes 100 kilograms toothpaste by the proportioning of A compositions in the table 8, to the RADIX CURCUMAE from Sichuan of China Chinese medicine extract that wherein adds 0.1%.Chinese medicine extract preparation method and toothpaste production method are with embodiment 1.
(2) select 100 kilograms for use by the proportioning of B compositions in the table 8, to the Guangxi zedoary Chinese medicine extract that wherein adds 10%.Chinese medicine extract preparation method and toothpaste production method are with embodiment 1.
(3) make 100 kilograms toothpaste by the proportioning of B compositions in the table 8, to the Rhizoma Curcumae Chinese medicine Chinese medicine extract that wherein adds 10%.Chinese medicine extract preparation method and toothpaste production method are with embodiment 1.
(4) make 100 kilograms toothpaste by the proportioning of A compositions in the table 8, to the RADIX CURCUMAE Chinese medicine extract that wherein adds 0.1%.Chinese medicine gold method for preparing extractive and toothpaste production method are with embodiment 1.
(5) make 100 kilograms toothpaste by the proportioning of B compositions in the table 8, to the Chinese medicine extract that wherein adds 0.2%.Chinese medicine extract preparation method and toothpaste production method are with embodiment 1.Wherein the parts by weight of each Chinese medicine extract consist of RADIX CURCUMAE from Sichuan of China: Guangxi zedoary: Rhizoma Curcumae=4: 3: 2.
(6) make 100 kilograms toothpaste by the proportioning of A compositions in the table 8, to the Chinese medicine Chinese medicine extract that wherein adds 0.6%.Chinese medicine extract preparation method and toothpaste production method are with embodiment 1.Wherein the parts by weight of each Chinese medicine extract consist of RADIX CURCUMAE from Sichuan of China: RADIX CURCUMAE: Rhizoma Curcumae=3: 2: 1.
(7) make 100 kilograms toothpaste by the proportioning of B compositions in the table 8, to the Chinese medicine extract that wherein adds 1%.Chinese medicine extract preparation method and toothpaste production method are with embodiment 1.Wherein the parts by weight of each Chinese medicine extract consist of RADIX CURCUMAE from Sichuan of China: Rhizoma Curcumae=3: 3.
(8) make 100 kilograms toothpaste by the proportioning of B compositions in the table 8, to the Chinese medicine extract that wherein adds 4%.Chinese medicine extract preparation method and toothpaste production method are with embodiment 1.Wherein the parts by weight of each Chinese medicine extract consist of RADIX CURCUMAE: Guangxi zedoary: Rhizoma Curcumae=3: 2: 2.
(9) make 100 kilograms toothpaste by the proportioning of A compositions in the table 8, to the Chinese medicine extract that wherein adds 6%.Chinese medicine extract preparation method and toothpaste production method are with embodiment 1.Wherein the parts by weight of each Chinese medicine extract consist of RADIX CURCUMAE: Rhizoma Curcumae=3: 2.
(10) make 100 kilograms toothpaste by the proportioning of A compositions in the table 8, to the Chinese medicine extract that wherein adds 8%.Chinese medicine extract preparation method and toothpaste production method are with embodiment 1.Wherein the parts by weight of each Chinese medicine extract consist of RADIX CURCUMAE from Sichuan of China: RADIX CURCUMAE=4: 2.
Embodiment 8
A kind of toothpaste that contains Chinese medicine extract, this Chinese medicine extract are single or blended RADIX CURCUMAE from Sichuan of China, RADIX CURCUMAE, Guangxi zedoary, the extract of Rhizoma Curcumae.All the other are with embodiment 1.
Embodiment 9
The toothpaste that contains Chinese medicine extract, this Chinese medicine extract are single RADIX CURCUMAE from Sichuan of China extract.All the other are with embodiment 1.
Embodiment 10
The toothpaste that contains Chinese medicine extract, this Chinese medicine extract are RADIX CURCUMAE from Sichuan of China, the mixed extract of Guangxi zedoary.All the other are with embodiment 1.
Embodiment 11
The toothpaste that contains Chinese medicine extract, this Chinese medicine extract are the mixed extract of RADIX CURCUMAE from Sichuan of China, RADIX CURCUMAE, Guangxi zedoary.All the other are with embodiment 1.
Embodiment 12
The toothpaste that contains Chinese medicine extract, this Chinese medicine extract are the mixed extract of RADIX CURCUMAE from Sichuan of China, RADIX CURCUMAE, Rhizoma Curcumae.All the other are with embodiment 1.
Embodiment 13
The toothpaste that contains Chinese medicine extract, the addition of Chinese medicine extract are the 0.1-10% of toothpaste gross weight.All the other are with embodiment 1.
Embodiment 14
The preparation method that contains the toothpaste of Chinese medicine extract, the preparation method that Chinese medicine extract adopts is: RADIX CURCUMAE from Sichuan of China, RADIX CURCUMAE, Guangxi zedoary, in the Rhizoma Curcumae any one or several raw medicinal material are ground into coarse powder, add 60-75% alcohol reflux secondary, 2 hours for the first time, 8 times of amount ethanol, 1.5 hours for the second time, 6 times of amount ethanol, filtration, filtrate recycling ethanol and to be concentrated into relative density be 1.06-1.08, spray drying gets the Chinese medicine extract of dry powder; The conventional base material mix homogeneously of Chinese medicine extract and toothpaste is made toothpaste.All the other are with embodiment 1.
Embodiment 15
The toothpaste that contains Chinese medicine extract, this Chinese medicine extract are 3.0 kilograms of single RADIX CURCUMAE from Sichuan of China extracts, and all the other compositions of its toothpaste and prescription are 3.0 kilograms of single RADIX CURCUMAE from Sichuan of China extracts, all the other compositions of its toothpaste and prescription are 20 kilograms of sorbitol, 20 kilograms of calcium carbonate, 8.0 kilograms of silicon dioxide, 0.8 kilogram of titanium dioxide, 0.5 kilogram of xanthan gum, 1.5 kilograms of sodium lauryl sulphates, 0.2 kilogram of sodium benzoate, 0.1 kilogram of saccharin sodium, 0.2 kilogram in essence, 45.7 kilograms in water.All the other are with embodiment 1.
Embodiment 16
The toothpaste that contains Chinese medicine extract among the embodiment 1-15 is used to whiten cleans the teeth.Sooner or later respectively brush one time tooth during use, smoking at ordinary times, the tooth of back brush of having tea, all the other are with embodiment 1.
Embodiment 17
The toothpaste that contains Chinese medicine extract among the embodiment 1-15 is used for removing speckle.Sooner or later respectively brush one time tooth during use, smoking at ordinary times, the tooth of back brush of having tea, all the other are with embodiment 1.
Embodiment 18
The toothpaste that contains Chinese medicine extract among the embodiment 1-15 is used for removing smoking patch tea speckle.Sooner or later respectively brush one time tooth during use, smoking at ordinary times, the tooth of back brush of having tea, all the other are with embodiment 1.
Embodiment 19
The Chinese medicine extract that contains among the embodiment 1-15 is used to whiten and cleans the teeth.Sooner or later respectively brush one time tooth during use, smoking at ordinary times, the tooth of back brush of having tea, all the other are with embodiment 1.
Embodiment 20
The Chinese medicine extract that contains among the embodiment 1-15 is used for removing speckle.Sooner or later respectively brush one time tooth during use, smoking at ordinary times, the tooth of back brush of having tea, all the other are with embodiment 1.
Embodiment 21
The Chinese medicine extract that contains among the embodiment 1-15 is used for removing smoking patch tea speckle.Sooner or later respectively brush one time tooth during use, smoking at ordinary times, the tooth of back brush of having tea, all the other are with embodiment 1.
Claims (7)
1, a kind of toothpaste that contains Chinese medicine extract is characterized in that: this Chinese medicine extract is the RADIX CURCUMAE from Sichuan of China extract.
2, the toothpaste that contains Chinese medicine extract according to claim 1 is characterized in that: the addition of Chinese medicine extract is the 0.1-10% of toothpaste gross weight.
3, a kind of preparation method that contains the toothpaste of Chinese medicine extract as claimed in claim 1 is characterized in that:
The preparation method that Chinese medicine extract adopts is: the RADIX CURCUMAE from Sichuan of China raw medicinal material is ground into coarse powder, add 60-75% alcohol reflux secondary, 2 hours for the first time, 8 times of amount ethanol, 1.5 hours for the second time, 6 times of amount ethanol, filtration, filtrate recycling ethanol and to be concentrated into relative density be 1.06-1.08, spray drying gets the Chinese medicine extract of dry powder; The conventional base material mix homogeneously of Chinese medicine extract and toothpaste is made toothpaste.
4, a kind of application of whitening and cleaning the teeth that contains the toothpaste of Chinese medicine extract as claimed in claim 1.
5, the toothpaste that contains Chinese medicine extract according to claim 1, it is characterized in that: this Chinese medicine extract is 3.0 kilograms of single RADIX CURCUMAE from Sichuan of China extracts, and all the other compositions of its toothpaste and prescription are 20 kilograms of sorbitol, 20 kilograms of calcium carbonate, 8.0 kilograms of silicon dioxide, 0.8 kilogram of titanium dioxide, 0.5 kilogram of xanthan gum, 1.5 kilograms of sodium lauryl sulphates, 0.2 kilogram of sodium benzoate, 0.1 kilogram of saccharin sodium, 0.2 kilogram in essence, 45.7 kilograms in water.
6, a kind of application of toothpaste in removing speckle that contains Chinese medicine extract as claimed in claim 1.
7, a kind of toothpaste that contains Chinese medicine extract as claimed in claim 1 is used in removing smoking patch or tea speckle.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03128352 CN1270694C (en) | 2003-07-11 | 2003-07-11 | Toothpaste containing extract from Chinese traditional medicine as well as preparing method and application |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 03128352 CN1270694C (en) | 2003-07-11 | 2003-07-11 | Toothpaste containing extract from Chinese traditional medicine as well as preparing method and application |
Publications (2)
| Publication Number | Publication Date |
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| CN1480126A CN1480126A (en) | 2004-03-10 |
| CN1270694C true CN1270694C (en) | 2006-08-23 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN 03128352 Expired - Fee Related CN1270694C (en) | 2003-07-11 | 2003-07-11 | Toothpaste containing extract from Chinese traditional medicine as well as preparing method and application |
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Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101161229B (en) * | 2006-10-13 | 2011-03-23 | 广东海洋大学 | Shuck beauty white toothpaste |
| CN107157888A (en) * | 2017-06-18 | 2017-09-15 | 何家平 | A kind of alumen tooth powder technique |
| CN112999109A (en) * | 2021-03-16 | 2021-06-22 | 江苏雪豹日化有限公司 | Modified biological lysozyme composition |
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2003
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| CN1480126A (en) | 2004-03-10 |
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