CN1265579A - Anhydrous gel deodorant compositions containing volatile nonpolar solvents - Google Patents
Anhydrous gel deodorant compositions containing volatile nonpolar solvents Download PDFInfo
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- CN1265579A CN1265579A CN 98807839 CN98807839A CN1265579A CN 1265579 A CN1265579 A CN 1265579A CN 98807839 CN98807839 CN 98807839 CN 98807839 A CN98807839 A CN 98807839A CN 1265579 A CN1265579 A CN 1265579A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q15/00—Anti-perspirants or body deodorants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0216—Solid or semisolid forms
- A61K8/0229—Sticks
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/31—Hydrocarbons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/361—Carboxylic acids having more than seven carbon atoms in an unbroken chain; Salts or anhydrides thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/30—Characterized by the absence of a particular group of ingredients
- A61K2800/31—Anhydrous
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Abstract
Disclosed are anhydrous gel deodorant compositions comprising from about 0.001 % to about 50 % by weight of deodorant active, fragrance, or combination thereof; from about 0.01 % to about 20 % by weight of a fatty acid salt gellant; from about 1 % to about 50 % by weight of a nonpolar volatile solvent having a solubility parameter of less than 8.0 (cal/cm<3>)<0.5>, a vapor pressure of from about 0.01 mmHg to about 6 mmHg at 25 DEG C, and a boiling point at 1 atm of less than about 250 DEG C; from about 1 % to about 10 % by weight of a polar solvent having a solubility parameter of from 12.5 (cal/cm<3>)<0.5> to about 25 (cal/cm<3>)<0.5> and optionally a moderately polar solvent having a solubility parameter of from about 8.0 (cal/cm<3>)<0.5> to less than 12.5 (cal/cm<3>)<0.5>. Also disclosed are anhydrous gel deodorant compositions comprising select combinations of metal salts of fatty acid gellants and glycerin. Also disclosed are anhydrous gel deodorant compositions containing improved combinations of deodorant actives, and gel deodorant compositions containing 1,2-hexanediol as a moderately polar solvent. These compositions provide improved performance, product clarity, and/or skin feel characteristics, and are especially effective at providing deodorant application which is milder to the skin and which causes little or no skin irritation.
Description
Invention field
The present invention relates to a kind of anhydrous gel deodorant compositions, said composition contains nonpolar volatile solvent and the polar solvent that is used in combination with it, gellant and deodorant activities material or spice.These compositionss are gentle and cause minimum skin irritation to skin, and have the advantages of good skin sense quality after coating is used.
Background of invention
It has been generally acknowledged that the human body body odor partly is to be caused by microorganism and the sweat gland secretion thing interaction zest fatty acid compound that produces.Except cleaning, a method controlling this abnormal flavour is at oxter local coating antiperspirant or deodorant compositions.
The deodorant compositions of gel form is the common especially a kind of mode that prevents or shelter the body odor that is produced with perspiring.This type of gel deodorant compositions generally is the form of solid or soft solid rod, and as other antiperspirant or deodorant products, also is that local coating is in the oxter or other skin areas.Yet gel deodorant is more sliding than other many antiperspirant or deodorant products usually on skin, so even there is visible residue to stay after coating, also be seldom.These gel deodorants generally contain gellant, make the polar solvent of gellant solubilising, deodorant activities material (as antibacterial, spice or other abnormal flavour masking materials).Usually used gellant comprises soap in above-mentioned system, for example C
12-C
22The sodium salt of fatty acid and potassium salt.Usually combine the polar solvent that forms the gel structure compositions comprises with soap: monohydric alcohol or dihydroxylic alcohols, and concrete as ethanol; And glycols, as the polypropylene glycol of propylene glycol, dipropylene glycol and other higher molecular weights.But many such gel deodorants are not soft concerning skin, and can cause over-drastic skin irritation.
So, an object of the present invention is to provide a kind of anhydrous gel deodorant compositions, said composition is to the skin gentleness and cause minimum skin irritation; But also the above-mentioned composition that provides during local coating and still had good dermal sensation characteristic afterwards.Another object of the present invention is to provide the gel deodorant compositions that contains the volatile nonpolar solvents that combines with polar solvent, and the above-mentioned composition that wherein randomly contains medium polar solvent is provided.
Summary of the invention
The present invention relates to anhydrous gel deodorant compositions, wherein contain the 0.001%-that has an appointment about 50% (weight) deodorant activities material, spice or its mixture; About 0.01%-about 20% (weight) fatty acid metal salts gellant; The nonpolar volatile solvent of about 50% (weight) of about 1%-, the solubility parameter of this solvent is less than 8.0 (cal/cm3) 0.5, and vapour pressure is about the about 6mmHg of 0.01mm Hg-in the time of 25 ℃, and mean boiling point is lower than about 250 ℃; With about 1%-about 10% (weight) polar solvent, the solubility parameter of this polar solvent is about 25 (cal/cm3) 0.5 of 12.5-.Anhydrous gel deodorant compositions in a preferred embodiment of the present invention contains glycerol as polar solvent, and wherein the part by weight of glycerol and soap is about 0.5: about 3: 1 of 1-.Contain in other preferred embodiments to be useful on and improve 1 of soft property and/or product transparency, 2-hexanediol solvent.Also preferred those contain the triclosan (triclosan) that can improve the deodorization effect and the compositions of triclocarban (triclocarban) deodorant activities mixture of substances.
Have been found that these anhydrous gel deodorant compositions have improved performance and dermal sensation characteristic, and effective especially when deodorization is used, they are gentle and cause minimum or do not cause skin irritation to skin.
Detailed Description Of The Invention
Anhydrous gel deodorant compositions of the present invention contains gellant, volatile nonpolar solvents, polar solvent and essence or deodorant activities material as solvent.These anhydrous gel deodorant compositions are suitable for local coating in the oxter or other suitable skin areas.The suitable form that adopts solid or soft solid rod of described compositions, but also can adopt the multiple non-bar-shaped preparation that is fit to be coated in oxter or other skin areas.
At this used term " anhydrous " is with regard to gel deodorant compositions of the present invention, and is meant that said composition does not contain water substantially; In gel deodorant, the content of preferred free moisture or additional water is more preferably less than about 1% (weight) less than about 5% (weight), and first-selected content is 0% (weight).
Be meant about 50% relative humidity and the about 25 ℃ ambient conditions that is under about 1 atmospheric pressure at this used term " environmental condition ".
" do not contain aromatic hydrocarbon substantially " and be meant that gel deodorant compositions of the present invention contains is less than about 10% (weight) at this used term, preferably be less than the aromatic hydrocarbon compounds of about 5% (weight), described aromatic hydrocarbon is selected from: australene, nopinene, d-limonene and other terpene compounds.
Anhydrous gel deodorant compositions of the present invention can contain, form from or basic composition from the present invention in this basis of addressing and determinant, and any additional or optional component, composition or determinant.
Except as otherwise noted, all herein percentage ratio, umber or ratios are in composition total weight.Weight for listed component all is based on content of active substance, therefore, except as otherwise noted, does not comprise the solvent or the by-product that may exist in the marketable material.
Deodorant activities material and spice
Anhydrous gel deodorant compositions of the present invention contains deodorant activities material, spice or its mixture, wherein the content of deodorization spice in compositions is about 50% (weight) of about 0.001%-, preferred about 20% (weight) of about 0.01%-, more preferably from about 0.1%-10% (weight).These deodorant activities materials and spice comprise any be fit to be coated in known on the body local skin or deodorizer or spice safely and effectively.
Unless specify in addition, generally be meant deodorant activities material or spice at this used term " active substance ", and term " deodorant activities material " specifically is meant the part material that can prevent or eliminate body odor due to the perspiration.Specifically be meant at this used term " spice " anyly can to hide or shelter body odor due to the perspiration, or make compositions have the part material of required aromatic odor.
A) deodorant activities material
The deodorant activities material that is applicable to anhydrous gel deodorant compositions of the present invention comprises any known or can effectively prevent or eliminate part material with the relevant body odor of perspiring.These deodorant activities materials are antibacterial (for example bactericide, antifungal), body odor absorbing material or its mixture normally.
Preferred deodorant activities material is an antibacterial; its non-limiting example comprises: cetab; cetylpyridinium chloride; benzethonium chloride; diisobutyl phenoxy group ethoxyethyl group dimethyl benzyl ammonium chloride; the N-sarcosyl; N-palmityl (palmethyl) sodium sarcosinate; the lauroyl sarcosine; N-myristoyl glycine; N-lauryl creatine acid potassium; trimethyl ammonium chloride; chlorine hydroxyl sodium lactate aluminum; triethyl citrate; three (cetyl) ammonio methacrylate; 2; 4; 4 '-three chloro-2 '-hydroxy diphenyl ether (triclosan); 3; 4; 4 '-trichlorine phosphinylidyne is for dianil (triclocarban); Diaminoalkyl amides compound (as L-lysine palmitic amide); citric acid; salicylic acid; the heavy metallic salt of Octopirox (piroctose), particularly its zinc salt and its acid; the heavy metallic salt of PTO (concrete) as vancide ZP; phenol zinc sulfate; farnesol and composition thereof.
Preferred deodorant activities material is triclosan, triclocarban and combination thereof, the concentration of triclosan or triclocarban about 1.0% (weight) of about 0.01%-of said composition preferably wherein, about 0.5% (weight) of 0.1%-more preferably from about, especially preferably about 0.1%-0.3% (weight); When compositions adopted triclosan and triclocarban simultaneously, both total concentrations were about 2.0% (weight) of about 0.01%-of compositions, about 1.0% (weight) of 0.2%-more preferably from about, about 0.6% (weight) of especially preferably about 0.2%-.Have found that, share deodorization effect that these two kinds of deodorant activities materials are produced and surpassed two kinds of material lists with deodorization effect sums.
The combination of preferred triclosan and triclocarban can effectively improve the deodoriging properties of described deodorant compositions, or contains any known deodorizer of the combinations thereof that is fit to be coated on the human body skin or the deodoriging properties of topical compositions.Therefore, the invention still further relates to a kind of control perspire by human body due to the method for body odor, this method is the combination with above-mentioned triclosan/triclocarban, or the appropriate combination thing local coating that contains above-mentioned triclosan/triclocarban combination is in the oxter or other skin areas.Contain the deodorant compositions of this combination for the overwhelming majority, need the about 2.0g deodorant compositions of the about 0.1g-of coating under each axillary fossa, suit every day to apply 1 or 2 time, more preferably every day 1 time.
Other deodorant activities materials comprise: the abnormal flavour absorbing material, as carbonate and bicarbonate, comprising alkali-metal carbonate and bicarbonate; Ammonium salt and tetraalkylammonium salt.Preferred sodium salt and the potassium salt that adopts this type of abnormal flavour absorbing material.
Preferred described anhydrous gel deodorant compositions is substantially devoid of convergence hidroschesis active matter matter, as the convergence salt or the complex of aluminum or zirconium.Herein, term " is substantially devoid of " and is meant that described gel deodorant compositions suits to contain to be lower than about 5% (weight), more preferably contains to be lower than 2% (weight), and first-selection contains the convergence hidroschesis active matter matter of 0% (weight).
B) spice
The spice that is applicable to anhydrous gel deodorant compositions of the present invention comprises any known or can effectively shelter body odor due to the perspiration, or makes compositions have the local coating material of required aromatic odor.These spice comprise any essence or essence chemicals that is fit to be coated on the skin.
Concentration of perfume in the anhydrous gel deodorant compositions should be able to effectively provide required aromatic character or shelter body odor, and wherein said body odor and compositions itself exist intrinsic relation, or emits bad smell relevant with the human sweat.In addition, the spice and any carrier reply skin that share with it that exist with above-mentioned contents level do not produce over-drastic sensation of pricking, particularly stave or chafe.Spice is generally water-insoluble essence form, but this essence dissolves in the anhydrous gel deodorant compositions.
One of ordinary skill in the art had produced the numerous species spice different with intensity already.Typical spice is disclosed in: " essence and correctives chemicals (armaticity chemicals) " (Perfume and Flavour Chemicals) that Arctander showed, I and II volume (1969); " essence of natural origin and flavoring material " (1960) with Arctander; In United States Patent (USP) 4322308 and the United States Patent (USP) 4304679 (these two pieces of patent documentations are hereby incorporated by); Disclosed fragrance component generally comprises but is not limited to: Volatile Phenols compounds (for example salicylic acid isopentyl ester, benzyl salicylate and Herba thymi vulgaris oil red); Essential oil (for example Oleum Pelargonii Graveolentis, Herba Pogostemonis oil and petitgrain oil); Tangerine oil; Extract and resin (for example Siam benzoin smectic material and opopanax gum shape material); " synthesize " oil (for example fragrant Bergamot 37 and 430, Geranium 76 and Pomeransol 314); Aldehyde and ketone compounds (for example B-methyl naphthyl ketone, right-tert-butyl group-A-hydrogenated methyl cinnamic aldehyde and right-tertiary pentyl-Ketohexamethylene); Polycyclic compound (for example coumarin and jara jara); Ester (diethyl phthalate for example, the phenylacetic acid phenyl chlorocarbonate, 1,4-encircles ester in the ninth of the ten Heavenly Stems (non-annelid-1: 4)).Spice also comprises: derived from flower class material and fruit, tangerine oil, absolute oil, aldehyde, balsam type material, Moschus and other animal perfume material (for example natural separator of civet, castor and Moschus), face cream etc. and alcohol compound (for example dimyrene alcohol (dimyrcetol), phenethanol and tetrahydrochysene dimethyl-octa three enols (tetrahydromuguol).The example that is suitable for use in this component in the spice of the present invention comprises: capraldehyde, hendecanal, undecenal, dodecanal, amyl cinnamic aldehyde, glycidyl methyl phenyl ethyl ester, methyl nonyl acetaldehyde, myristic aldehyde, n-nonanoic acid lactone, aldehyde C-9, octanal, undecalactone, jasminolene, benzaldehyde, vanillin, heliotropine, Camphora, right-the hydroxyl phenol butanone, 6-acetyl group-1; 1; 3; 4; 4, the mixture of 6-hexamethyl naphthane, Alpha-Methyl ionone, γ-methyl ionone and amyl group Ketohexamethylene or these components.
Other spice that is suitable for is those spice (after this be called abnormal flavour and shelter spice) that can shelter or help to shelter abnormal flavour due to the perspiration, its some non-limiting example is disclosed among United States Patent (USP) 5554588,4278658,5501805 and european patent application 684037 A1, and these documents all are incorporated herein by reference in full at this.It is that those deodorization values of measuring according to the described deodorization pH-value determination pH of european patent application 684037 A1 method are at least about 0.25 that preferred abnormal flavour is sheltered spice, and preferably about 0.25-is about 3.5, more preferably from about the spice of 0.9-about 3.5.
In this used spice, can also contain solubilizing agent well known by persons skilled in the art, diluent or solvent.Arctander discloses this type of material at " essence and flavoring chemicals (aromachemicals) " in I and the II volume (1969).These materials generally include dipropylene glycol, diethylene glycol, C
1-C
6Pure and mild benzylalcohol.
Gellant
Anhydrous gel deodorant compositions of the present invention contains fatty acid metal salts as gellant, is used to compositions that required hardness and coating characteristic is provided.The concentration of gellant is about 20% (weight) of about 0.01%-of gel deodorant compositions, about 10% (weight) of preferably about 0.1%-, about 8% (weight) of 1%-more preferably from about, about 7% (weight) of especially preferably about 3%-.
Can adopt any soap gellant in the anhydrous gel deodorant compositions of the present invention, but condition is selected gellant can be at about 50 ℃-Yue 150 ℃, preferred about 50 ℃-Yue 120 ℃, melt under the more preferably from about 60 ℃-Yue 100 ℃ processing temperature, and form solution or other uniform liquid or liquid dispersion with selected solvent system as herein described.Selected gellant also must be for gel deodorant compositions provides required gel-type vehicle, so that compositions has required hardness or sprawls characteristic after preparation and completion of processing.
Preferred soap is that those have about 40 carbon atoms of about 12-, about 22 carbon atoms of preferably about 12-, about 20 carbon atoms of 16-more preferably from about, the soap of about 18 carbon atoms of first-selection.The salt-forming cation that is adapted at adopting in the above-mentioned gellant comprises slaine, for example: and alkali metal salt, as sodium salt and potassium salt; And alkali salt, as magnesium salt and aluminum salt.Preferably select sodium salt and potassium salt for use, more preferably sodium stearate, sodium palmitate, sodium laurate, arachidic acid sodium, sodium behenate, potassium stearate, potassium palmitate, Sodium myristate, aluminum monostearate and combination thereof.First-selected sodium stearate.
The non-limiting example that is fit to be used for to prepare the fatty acid of fatty acid gellant comprises: acid, for example myristic acid, Palmic acid, stearic acid, oleic acid, mountain Yu acid, arachidic acid, lauric acid, linolenic acid, linoleic acid, heptadecanoic acid or its combination.Preferred these fatty acid derived are cocos nucifera oil, Adeps Bovis seu Bubali, lanoline, fish oil, Cera Flava, Petiolus Trachycarpi oil, Oleum Arachidis hypogaeae semen, olive oil, Oleum Gossypii semen, Oleum Glycines, Semen Maydis oil, rapeseed oil, rosin acid, tallow and other natural origin freely, or by known synthetic or the fatty acid that semisynthesis is derived and obtained of formulation art technical staff.
Volatile nonpolar solvents
Anhydrous gel deodorant compositions of the present invention contains the volatile nonpolar solvents with selected vapour pressure and solubility parameter.The concentration of volatile nonpolar solvents in gel deodorant compositions is about 50% (weight) of about 1%-of said composition, about 40% (weight) of preferably about 10%-, more preferably about 40% (weight) of 20%-, about 40% (weight) of especially preferably about 30%-.
Be meant the volatile nonpolar solvents of anhydrous gel deodorant compositions of the present invention at this used term " volatility ", and be meant specifically that in this article the vapour pressure of measuring is the about 6mm Hg of about 0.01mm Hg-under 25 ℃, the preferred about 1.5mm Hg of about 0.02mm Hg-, and the mean boiling point under 1 atmospheric pressure (1atm) is lower than about 250 ℃, and preferably the mean boiling point under 1 atmospheric pressure is lower than about 235 ℃ non-polar solven.
Be meant the volatile nonpolar solvents of anhydrous gel deodorant compositions of the present invention at this used term " nonpolar ", and be meant specifically that in this article solubility parameter is less than 8.0 (cal/cm
3)
0.5, preferred about 5.0 (cal/cm
3)
0.5Extremely less than 8.0 (cal/cm
3)
0.5, more preferably 6.0 (cal/cm
3)
0.5To about 7.60 (cal/cm
3)
0.5Volatile solvent.
Can measure volatile nonpolar solvents and other solubility of substances parameter by the known method that is used to obtain the relative polarity feature of solvent or other material of chemical field technical staff.To the description of solubility parameter and assay method thereof be disclosed in C.D.Vaughan " product, packing, infiltration and anticorrosion in the dissolubility effect " 103 " cosmetics and toilet articles " (Cosmetics andToiletries) 47-69,1988.10; And C.D.Vaughan, " the practical solubility parameter in the cosmetic formulations ", 36 " Society of Cosmetic Chemists magazine " (J.Soc.Cosmetic Chemists) 319-333,1988 9/10 month, above-mentioned disclosure was hereby incorporated by.
The volatile nonpolar solvents that is applicable to anhydrous gel deodorant compositions is those solvents with above-mentioned vapour pressure and solubility parameter, wherein can comprise hydro carbons, esters, amide-type and ether compound with regulation vapour pressure and solubility parameter, the preferred solvent that adopts non-polar hydrocarbon, it can be the hydro carbons of ring-type, straight or branched configuration, first-selected branched-chain hydrocarbons compounds.
Most preferred volatile nonpolar solvents is to have regulation vapour pressure and solubility parameter and contain about 30 carbon atoms of the 4-that has an appointment, about 20 carbon atoms of preferably about 4-, the more preferably from about branched-chain hydrocarbons of about 20 carbon atoms of 6-.First-selected gel deodorant compositions contains the combination of two or more above-mentioned branched-chain hydrocarbons, and wherein these two or more branched-chain hydrocarbons have different molecular weight, carbon atom number and/or chain configuration.The concrete non-limiting example of these first-selected hydrocarbon solvent combinations comprises: available from Exxon ChemicalCompany (Baytown, Texas U.S.A) isoparaffin series products, be called Isopar M (C13-C14 isoparaffin), Isopar C (C7-C8 isoparaffin), Isopar E (C8-C9 isoparaffin), Isopar G (C10-11 isoparaffin), Isopar L (C11-C13 isoparaffin) and Isopar H (C11-C12 isoparaffin).Other non-limiting example of the branched-chain hydrocarbons that is suitable for comprises: Permethyl 99A (Fancol ID), Permethyl 102A (Isoeicosane), Permethyl 101A (different hexadecane) and combination thereof.The product of Permethyl series is available from Preperse, Inc., South Plainfield, NewJersey, U.S.A..The non-limiting example of the branched-chain hydrocarbons that other are suitable for comprises petroleum distillate, as those product Soltrol 130, Soltrol 170 available from Phillips Chemical, and those product Shell Sol-70 available from Shell ,-71 and-2033.
Other non-limiting example that is applicable to the nonpolar volatile solvent of anhydrous gel deodorant compositions of the present invention comprises: dibutyl adipate, diisopropyl adipate, dodecane, octane, decane and combination thereof.Another example comprises available from Exxon and is called C11-C15 alkane and the cycloalkane of Exxsol D80.
Polar solvent
Anhydrous gel deodorant compositions of the present invention contains one or more polar solvents with selected high solubility parameter.Polar solvent concentration in the anhydrous gel deodorant compositions changes with concrete combination, gellant and other optional solvents of compositions Semi-polarity solvent, but its concentration should not surpass about 10% (weight) of gel deodorant compositions, about 10% (weight) of preferably about 0.5%-, about 8% (weight) of 1%-more preferably from about, about 7% (weight) of especially preferably about 3%-, wherein the solubility parameter that this polar solvent had is 12.5 (cal/cm at least
3)
0.5, preferred about 12.5 (cal/cm
3)
0.5-Yue 25 (cal/cm
3)
0.5, more preferably 12.5 (cal/cm
3)
0.5-Yue 17.0 (cal/cm
3)
0.5
The non-limiting example that is applicable to the polar solvent of anhydrous gel deodorant compositions of the present invention comprises: monohydric alcohol, polyhydric alcohol and combination thereof, the example be as the C1-C20 monohydric alcohol, preferred C2-C8 monohydric alcohol; And Polyethylene Glycol and polypropylene glycol with 2-7 repetition ethyoxyl or propoxyl group; And have 2-16 and repeat glyceryl polyglycereol.
The instantiation that is applicable to the polar solvent of described anhydrous gel deodorant compositions includes but not limited to: glycerol, propylene glycol, dipropylene glycol, ethanol, water, tripropylene glycol, butanediol, propylene glycol monomethyl ether, dipropylene glycol methyl ether and combination thereof.Wherein first-selected glycerol.
The preferred embodiment of gel deodorant compositions of the present invention is that those contain glycerol as polar solvent and contain the compositions of above-mentioned soap as gellant, wherein the part by weight of glycerol and soap is about 0.5: about 3: 1 of 1-, preferred about 0.8: about 1.5: 1 of 1-.Find, this close limit proportionate relationship of glycerol and soap can make fully hard gel stick in the gel deodorant compositions, can also adopt enough low processing temperature to prepare or process thus, thereby farthest reduce or eliminate the thermal degradation of heat-sensitive material in the compositions.The first-selected mixture that adopts sodium stearate and glycerol.
Preferred anhydrous gel deodorant compositions of the present invention is substantially devoid of propylene glycol, dipropylene glycol or its combination.Herein, used term " is substantially devoid of " and is meant that described compositions suits to contain to be less than 20% (weight), and more preferably less than 10% (weight), first-selection contains propylene glycol, dipropylene glycol or its combination of 0% (weight).
Being fit to as used herein, the non-limiting example of other polar solvent is disclosed in: United States Patent (USP) 5429816; " cosmetic conduct and learning, Science and Technology " (Cosmetics, Science and Technology) the 1st volume, 27-104 (Balsam; Sagarin edits) (1972); United States Patent (USP) 4202879; With United States Patent (USP) 4816261; These documents are incorporated herein by reference in full at this.
Medium polar solvent
Gel deodorant compositions of the present invention can also contain one or more medium polar solvents with selected moderate solubility parameter.Except with after this described polar solvent share, can also adopt this optional solvents in the gel deodorant compositions.In the transportation or the process of long term storage, particularly when transportation or to store be when carrying out at warmer weather or under hot condition of storage, medium polar solvent helps to reduce gel deodorant compositions generation syneresis.Medium polar solvent also helps to reduce the spice that can cause in the gel deodorant compositions and the processing temperature of other similar substance generation thermal degradation.
Medium polar solvent comprises that one or more solubility parameters are about 8.0 (cal/cm
3)
0.5Extremely less than 12.5 (cal/cm
3)
0.5, preferred about 9.0 (cal/cm
3)
0.5Extremely less than 12.5 (cal/cm
3)
0.5Solvent, about 40% (weight) of the preferably about 0.1%-of the concentration of medium polar solvent wherein in gel deodorant compositions, more preferably from about about 30% (weight) of 5%-.Should depend on other solvents and gellant selected in the gel deodorant compositions to the selection of the concrete content of medium polar solvent.
The non-limiting example that is applicable to the medium polar solvent in the gel deodorant compositions comprises aliphatic alcohol ethyoxyl ether, polyol ester, fatty acid ester, the Polyethylene Glycol with at least 8 ethyoxyls, the polypropylene glycol with at least 8 propoxyl group with about 30 carbon atoms of about 8-, non-polymerization glycol and the combination thereof with at least 4 carbon atoms.
The concrete non-limiting example that is applicable to the medium polar solvent of gel deodorant compositions comprises: single isostearate propylene glycol ester; The PPG-3-myristyl ether; PEG-8; Hexanediol; 1, the 2-hexanediol; The PPG-14-butyl ether; DIMETHYLISOSORBIDE (isosorbide) and combination thereof.Preferred hexanediol, PPG-3 myristyl ether, single isostearic acid propylene glycol ester, 1,2-hexanediol and combination thereof.Have found that, contain 1, the soft property the when anhydrous gel deodorant compositions of 2-hexanediol can more effectively improve product transparency and local skin coating.
Optional component
Gel deodorant compositions of the present invention can also contain one or more physics that can change compositions, chemistry, cosmetic conduct and learning or aesthetic characteristic or play the optional member of additional " activity " composition effect when deposition on skin.Compositions also can contain optional inert component.Known many examples of such optional components are applied in deodorizer or other compositions for use in personal care, and the above-mentioned optional components of the also suitable employing of gel deodorant compositions of the present invention, but it is compatible with above-mentioned solvent that condition is these optional, materials, or properties of product are not produced unsuitable infringement.
The non-limiting example that is applicable to the optional components of gel deodorant compositions of the present invention comprises: the pH buffer agent; Additional isostearyl glyceryl pentaerythrityl ether; Wetting agent; Emollient; Dyestuff and pigment; Medicine; Antiseptic; With emollient can for example be Aloe, allantoin, D-panthenol, American Avocado Tree oil and other plant oil, and lichens extract.
Preparation method
Can make compositions of the present invention by the known method that is used to prepare gel deodorant compositions of any one of ordinary skill in the art.Be clear that very that for these those skilled in the art concrete preparation method should depend on the specific selection to the type of used composition and amount.
Usually, compositions of the present invention can be by preparing polar solvent, volatile nonpolar solvents, deodorant activities material and the mutually blended method of other any optional solvents.Under stirring condition, add gellant and, make gellant fusion and formation clarification or transparent liquid basically extremely about 75 ℃-Yue 100 ℃ of mixture heated.With gained solution cooling, add spice (if can use) again, in subsequently that refrigerative compositions impouring is about 70 ℃ appropriate containers or allotter, make the composition cools in container or the allotter solidify, or with composition cools to room temperature.
Using method
Body odor due to can anhydrous gel deodorant compositions local coating of the present invention being perspired with control on skin by any known or effective method.These methods comprise that the gel deodorant compositions of the present invention with safe and effective amount is coated in other zones of oxter or human body skin.At this, term " safe and effective amount " is meant when the part is coated on the skin body odor due to can effectively shelter, reduce or eliminate human body perspires, simultaneously with the gel deodorant compositions consumption of rational danger/when useful ratio is applied to human body safely.At this, the about 2.0g/ of the normally about 0.1g-of a safe and effective amount axillary fossa.Suit compositions is applied 1 or 2 time preferred every day 1 time every day in oxter or other skin areas.
Embodiment
The following example is for example understood the specific embodiments of anhydrous gel deodorant compositions of the present invention, and comprising the method for making and using, but these embodiment do not play the qualification effect.One of ordinary skill in the art can make other improvement according to aim of the present invention and scope.
Each preparation of compositions that exemplifies be by will be except gellant applicatory and spice all list component and mix, and the mixture that under agitation heats these components is to being higher than the gellant fusing point but be lower than 110 ℃ temperature.Continuing to add gellant under the heating and stirring this mixture until being clarified substantially or transparent liquid subsequently, this moment is with liquid cools to 65 ℃-80 ℃.Under agitation in refrigerative liquid, add spice.To contain subsequently in the suitable allotter of liquid spice impouring or other containers, be cooled to room temperature so that its curing.
Table 1
| Component | Embodiment | |||||||
| ???1 | ????2 | ???3 | ???4 | ???5 | ???6 | ???7 | ???8 | |
| ??Isopar?V | ???7 | ????30 | ???- | ???- | ???7 | ???29.75 | ???- | ???- |
| ??Isopar?M | ???40.45 | ????5 | ???- | ???18.1 | ???40.2 | ???5 | ???- | ???18.1 |
| ??Isopar?L | ???- | ????- | ???- | ???18.1 | ???- | ???- | ???- | ???18.1 |
| ??Permethyl?99A | ???- | ????- | ???27.75 | ???- | ???- | ???- | ???27.50 | ???- |
| Butyl stearate | ???- | ????25 | ???14.75 | ???17 | ???- | ???25 | ???14.75 | ???17 |
| Polydimethylsiloxane 50 centistokes (cs) | ???- | ????- | ???12 | ???12 | ???- | ???- | ???12 | ???12 |
| Single isostearic acid propylene glycol ester | ???3.5 | ????16 | ???7 | ???6.5 | ???3.5 | ???16 | ???7 | ???6.5 |
| The PPG-3 myristyl ether | ???3.5 | ????- | ???- | ???0.6 | ???3.5 | ???- | ???- | ???0.6 |
| Mineral oil | ???15 | ????- | ???- | ???- | ???15 | ???- | ???- | ???- |
| Hexanediol | ???12.75 | ????15 | ???10 | ???16.75 | ???12.75 | ???15 | ???10 | ???16.50 |
| Glycerol | ???2.5 | ????3 | ???3 | ???3.35 | ???2.5 | ???3 | ???3 | ???3.35 |
| Propylene glycol | ???- | ????- | ???- | ???- | ???- | ???- | ???- | ???- |
| Ethanol | ???6 | ????- | ???- | ???- | ???6 | ???- | ???- | ???- |
| Spice | ???5.5 | ????2.5 | ???3.5 | ???3.4 | ???5.5 | ???2.5 | ???3.5 | ???3.4 |
| Triclocarban | ???- | ????- | ???- | ???- | ???0.25 | ???0.25 | ???0.25 | ???0.25 |
| Triclosan | ???0.3 | ????0.3 | ???0.3 | ???0.3 | ???0.3 | ???0.3 | ???0.3 | ???0.3 |
| Sodium stearate | ???3.5 | ????3.2 | ???3.7 | ???3.9 | ???3.5 | ???3.2 | ???3.7 | ???3.9 |
| Diisopropyl adipate | ???- | ????- | ???18 | ???- | ???- | ???- | ???18 | ???- |
Table 2
| Component | Embodiment | ||||||||
| ???9 | ??10 | ???11 | ???12 | ???13 | ??14 | ??15 | ??16 | ??17 | |
| ??Isopar?V | ???7 | ??30 | ???- | ???- | ???7 | ??29.75 | ??- | ??- | ??- |
| ??Isopar?M | ???40.45 | ??5 | ???- | ???18.1 | ???40.2 | ??5 | ??- | ??18.1 | ??11.5 |
| ??Isopar?L | ???- | ??- | ???- | ???18.1 | ???- | ??- | ??- | ??18.1 | ??11.5 |
| ??Permethyl?99A | ???- | ??- | ???27.75 | ???- | ???- | ??- | ??27.50 | ??- | ??- |
| Butyl stearate | ???- | ??25 | ???14.75 | ???17 | ???- | ??25 | ??14.75 | ??17 | ??15.9 |
| Polydimethylsiloxane 50 centistokes (cs) | ???- | ??- | ???12 | ???12 | ???- | ??- | ??12 | ??12 | ??- |
| Single isostearic acid propylene glycol ester | ???3.5 | ??16 | ???7 | ???6.5 | ???3.5 | ??16 | ??7 | ??6.5 | ??22.0 |
| The PPG-3 myristyl ether | ???3.5 | ??- | ???- | ???0.6 | ???3.5 | ??- | ??- | ??0.6 | ??- |
| Mineral oil | ???15 | ??- | ???- | ???- | ???15 | ??- | ??- | ??- | ??- |
| Tripropylene glycol | ???- | ??- | ???- | ???- | ???- | ??- | ??- | ??- | ??25.0 |
| 1, the 2-hexanediol | ???12.75 | ??15 | ???10 | ???16.75 | ???12.75 | ??15 | ??10 | ??16.50 | ??- |
| Glycerol | ???2.5 | ??3 | ???3 | ???3.35 | ???2.5 | ??3 | ??3 | ??3.35 | ??3.8 |
| Ethanol | ???6 | ??- | ???- | ???- | ???6 | ??- | ??- | ??- | ??- |
| Spice | ???5.5 | ??2.5 | ???3.5 | ???3.4 | ???5.5 | ??2.5 | ??3.5 | ??3.4 | ??3.5 |
| Triclocarban | ???- | ??- | ???- | ???- | ???0.25 | ??0.25 | ??0.25 | ??0.25 | ??0.25 |
| Triclosan | ???0.3 | ??0.3 | ???0.3 | ???0.3 | ???0.3 | ??0.3 | ??0.3 | ??0.3 | ??0.3 |
| Sodium stearate | ???3.5 | ??3.2 | ???3.7 | ???3.9 | ???3.5 | ??3.2 | ??3.7 | ??3.9 | ??5.5 |
| Diisopropyl adipate | ???- | ??- | ???18 | ???- | ???- | ??- | ??18 | ??- | ??- |
| Polysorbas20 | ???- | ??- | ???- | ???- | ???- | ??- | ??- | ??- | ??0.75 |
The gained above-mentioned composition is a gel deodorant, after this with this deodorizer local coating in the oxter, consumption is about the about 2g/ of a 0.1g-axillary fossa.The compositions of coating can effectively alleviate, shelters or eliminate the abnormal flavour of perspiration, and during applying and have the advantages of good skin sensation afterwards.The compositions of coating is soft and cause minimum or do not cause skin irritation to skin.The compositions that contains the combination of triclocarban and triclosan can very provide the deodorization effect effectively.Contain 1, the compositions of 2-hexanediol has been improved transparency of products.Except as otherwise noted, all amounts that exemplify all are based on the weight-weight percent of composition total weight.
Claims (10)
1. anhydrous gel deodorant compositions, wherein contain:
(a) the deodorant activities material of 0.001%-50% weight, spice or its combination;
(b) the fatty acid metal salts gellant of 0.01%-20% weight;
(c) the nonpolar volatile solvent of 1%-50% weight, its solubility parameter is less than 8.0 (cal/cm
3)
0.5, and the vapour pressure under 25 ℃ is 0.01mm Hg-6mmHg, mean boiling point is lower than 250 ℃; With
(d) polar solvent of 1%-10% weight, its solubility parameter are 12.5-25 (cal/cm
3)
0.5
2. the described anhydrous gel deodorant compositions of claim 1, wherein said composition contains the water that is less than 1% weight, and wherein said soap is the fatty acid alkali metal salt with 12-22 carbon atom.
3. claim 1 or 2 described anhydrous gel deodorant compositions, wherein said nonpolar volatile solvent is the volatile, branched hydrocurbon with 4-40 carbon atom, its solubility parameter is 5 (cal/cm
3)
0.5Extremely less than 8.0 (cal/cm
3)
0.5, and vapour pressure is 0.01mmHg-1.5mmHg under 25 ℃.
4. the described anhydrous gel deodorant compositions of claim 3, wherein said compositions contains two or more combinations that has different molecular weight and also contain the volatile, branched hydrocurbon of 6-20 carbon atom separately.
5. the described anhydrous gel deodorant compositions of claim 4, wherein said volatile, branched hydrocurbon is selected from C13-C14 isoparaffin, C7-C8 isoparaffin, C8-C9 isoparaffin, C10-C11 isoparaffin, C11-C13 isoparaffin, C11-C12 isoparaffin and combination thereof.
6. aforesaid right requires each described anhydrous gel deodorant compositions, and wherein said polar solvent is selected from: glycerol, propylene glycol, dipropylene glycol, ethanol, tripropylene glycol, butanediol, methyl proxitol, dipropylene glycol methyl ether and combination thereof.
7. the described anhydrous gel deodorant compositions of claim 6, wherein said polar solvent contains glycerol, and wherein the part by weight of glycerol and fatty acid gellant is 0.5: 1-3: 1.
8. aforesaid right requires each described anhydrous gel deodorant compositions, and wherein said deodorant activities material is selected from: the triclocarban of 0.01%-1.0% weight, the triclosan of 0.01%-1.0% weight and combination in any thereof.
9. aforesaid right requires each described anhydrous gel deodorant compositions, and wherein said composition also contains the medium polar solvent of 0.1%-40% weight, and it has 8.0 (cal/cm
3)
0.5Extremely less than 12.5 (cal/cm
3)
0.5Solubility parameter.
10. the described anhydrous gel deodorant compositions of claim 9, wherein said medium polar solvent contains 1, the 2-hexanediol.
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88093697A | 1997-06-23 | 1997-06-23 | |
| US08/880,936 | 1997-06-23 | ||
| US7124698A | 1998-05-01 | 1998-05-01 | |
| US09/071,246 | 1998-05-01 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN1265579A true CN1265579A (en) | 2000-09-06 |
Family
ID=26752004
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 98807839 Pending CN1265579A (en) | 1997-06-23 | 1998-06-10 | Anhydrous gel deodorant compositions containing volatile nonpolar solvents |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP0989843A1 (en) |
| CN (1) | CN1265579A (en) |
| AU (1) | AU7833198A (en) |
| BR (1) | BR9810296A (en) |
| WO (1) | WO1998058624A1 (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107308481A (en) * | 2017-06-30 | 2017-11-03 | 广东爱车小屋实业发展股份有限公司 | Alcohol-free air freshener and preparation method thereof |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5968489A (en) * | 1998-05-01 | 1999-10-19 | The Procter & Gamble Company | Antiperspirant composition containing 1,2-hexanediol |
| US6013248A (en) * | 1998-05-01 | 2000-01-11 | The Procter & Gamble Company | Deodorant compositions containing 1,2-hexanediol |
| US5976514A (en) * | 1998-11-20 | 1999-11-02 | Procter & Gamble Company | Low-irritation antiperspirant and deodorant compositions containing a volatile, nonpolar hydrocarbon liquid |
| CA2366601C (en) | 1999-03-25 | 2010-06-01 | 3M Innovative Properties Company | Non-stinging coating composition |
| FR2794980B1 (en) * | 1999-06-18 | 2001-09-07 | V Man Fils Ets | ARTICLE FOR CONTROLLED AND SUBSTANTIALLY REGULAR RELEASE OF A VOLATILE ORGANIC SUBSTANCE |
| US6399049B1 (en) | 1999-08-24 | 2002-06-04 | The Procter & Gamble Company | Compositions containing solubilized antiperspirant active |
| US6126928A (en) * | 1999-08-24 | 2000-10-03 | The Procter & Gamble Company | Compositions containing solubilized, acid-enhanced antiperspirant active |
| US6468511B1 (en) | 2000-05-19 | 2002-10-22 | Colgate-Palmolive Company | Emulsions with naphthalate esters |
| DE10205190B4 (en) | 2002-02-08 | 2017-06-08 | Beiersdorf Ag | 2-methyl-1,3-propanediol-containing preparations |
| DE102005051868A1 (en) * | 2005-10-25 | 2007-04-26 | Beiersdorf Ag | Use of 1,2-alkanediols to improve the skin feel of alkaline cleansing preparations |
| CN101677921A (en) * | 2007-06-19 | 2010-03-24 | 考格尼斯知识产权管理有限责任公司 | Cosmetic preparations containing hydrocarbons |
| DE102011002863A1 (en) | 2011-01-19 | 2012-07-19 | Henkel Ag & Co. Kgaa | Antiperspirant sticks with improved long-term stability |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4617185A (en) * | 1984-07-13 | 1986-10-14 | The Procter & Gamble Company | Improved deodorant stick |
| US4724139A (en) * | 1985-05-08 | 1988-02-09 | Victor Palinczar | Antiperspirant stick |
| US4781917A (en) * | 1987-06-26 | 1988-11-01 | The Proctor & Gamble Company | Antiperspirant gel stick |
-
1998
- 1998-06-10 CN CN 98807839 patent/CN1265579A/en active Pending
- 1998-06-10 AU AU78331/98A patent/AU7833198A/en not_active Abandoned
- 1998-06-10 WO PCT/US1998/012016 patent/WO1998058624A1/en not_active Application Discontinuation
- 1998-06-10 BR BR9810296-6A patent/BR9810296A/en not_active Application Discontinuation
- 1998-06-10 EP EP98926511A patent/EP0989843A1/en not_active Withdrawn
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107308481A (en) * | 2017-06-30 | 2017-11-03 | 广东爱车小屋实业发展股份有限公司 | Alcohol-free air freshener and preparation method thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| EP0989843A1 (en) | 2000-04-05 |
| WO1998058624A1 (en) | 1998-12-30 |
| AU7833198A (en) | 1999-01-04 |
| BR9810296A (en) | 2001-12-26 |
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